Revista Colombiana de Reumatología (English Edition)最新文献

{"title":"Characteristics of rheumatic patients who consult digital information sources","authors":"Maria Pía Izaguirre Germain ,&nbsp;Paola Ávila ,&nbsp;Nauan Fara ,&nbsp;Julia Pretini ,&nbsp;María Elena Gaona ,&nbsp;Pia Pissani ,&nbsp;Maira Arias Saavedra ,&nbsp;Valeria Aquino ,&nbsp;Mariana Espindola Echazu ,&nbsp;Manuela Laffont ,&nbsp;Magdalena Acevedo ,&nbsp;Lucrecia Garcia Faura ,&nbsp;Romina Hassan ,&nbsp;Karen Roberts ,&nbsp;Jorge Alejandro Brigante ,&nbsp;Damaris Álvarez ,&nbsp;Marina Laura Micelli ,&nbsp;Vanesa Laura Cosentino ,&nbsp;Sandra Fabiana Montoya ,&nbsp;Gabriel Sequeira ,&nbsp;Eduardo Mario Kerzberg","doi":"10.1016/j.rcreue.2024.11.003","DOIUrl":"10.1016/j.rcreue.2024.11.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Many patients use the internet as a source of health information and to create and share content of diverse quality of evidence, complementing and even competing with traditional sources of information.</div></div><div><h3>Objectives</h3><div>To evaluate differences between rheumatic patients who consult digital information sources (DISs) and those who do not (Non-DISs), and their perception of the credibility attributed to these sources by both groups.</div></div><div><h3>Materials and Methods</h3><div>An observational cross-sectional study was conducted through an anonymous survey of patients with rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, and spondyloarthritis. Patients were asked about their search for information from different DISs or Non-DISs. Patients rated the credibility they assigned to the different sources on a scale of 0–10, where 0 was no credibility and 10 was the maximum possible credibility.</div></div><div><h3>Results</h3><div>A total of 402 patients (79% female) were surveyed. Two hundred and seven (51%) had consulted at least one DIS during the previous year (DISs group). The DISs group had consulted a total of 5 DISs and Non-DISs (First-Third Quartile: 3–7) vs. 2 (First-Third Quartile: 1–3) in the Non-DISs group (<em>P</em> &lt; .001). The number of searches in DISs was higher at younger ages (OR .97 95% CI .95–.99) and at higher levels of education (secondary vs. primary OR 2.0; 95% CI 1.05–3.85). The DISs group assigned higher credibility to Facebook and YouTube than the other patients (median credibility of 6/10 and 6/10 vs. 2/10 and 1/10 respectively; <em>P</em> &lt; .001). However, they did not assign lower credibility to traditional sources.</div></div><div><h3>Conclusions</h3><div>DISs are more frequently consulted by a younger population with a higher level of education. These patients consult multiple sources, but do not assign lower credibility to traditional information sources.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 43-48"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical convergence: An exceptional case of sarcoidosis and tuberculosis with multiple organic manifestations. Case report","authors":"Néstor Correa-González ,&nbsp;María Claudia Díaz ,&nbsp;Keyla Jemihah Triana Ángel ,&nbsp;María Daniela Polania ,&nbsp;Natalia Remolina Murillo ,&nbsp;Pilar Alarcón Robles","doi":"10.1016/j.rcreue.2024.11.004","DOIUrl":"10.1016/j.rcreue.2024.11.004","url":null,"abstract":"<div><h3>Introduction</h3><div>The diagnosis of sarcoidosis is challenging, especially if the patient has concomitant infectious symptoms. Furthermore, the overlap of immune-mediated and infectious pathologies is not uncommon.</div></div><div><h3>Objective</h3><div>To report a rare case of association between tuberculosis and sarcoidosis</div></div><div><h3>Materials and methods</h3><div>Description of the clinical characteristics of a patient who presented with sarcoidosis superimposed on tuberculosis.</div></div><div><h3>Results</h3><div>The case of a 29-year-old man with ocular, cutaneous, and systemic symptoms is described. Uveitis and chronic non-caseating granulomatous findings were diagnosed in the skin, lungs, and lymph nodes. Suspicion of tuberculosis led to positive molecular biology tests only in the lymph node biopsy. An overlap of sarcoidosis and tuberculosis was determined, and combined treatment with glucocorticoids and anti-tuberculosis agents was initiated, resulting in improvement of the patient.</div></div><div><h3>Conclusions</h3><div>Sarcoidosis and tuberculosis share characteristics from their aetiology to clinical manifestations, posing a challenge in clinical differentiation. Cases have been documented where both diseases overlap in the same patient.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 95-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relative gene expression levels of the gene coding for monocyte chemoattractant protein-1 (MCP-1) as a urinary biomarker in lupus nephropathy","authors":"Esther Casablanca Alarcón ,&nbsp;Mabel de la Cruz Mendoza ,&nbsp;María de los Ángeles Terán de Baudoin ,&nbsp;Rolando Pastén Vargas ,&nbsp;Manuel Montero Jauregui ,&nbsp;Carlos Guachalla Castro ,&nbsp;Luis Fernando Sosa Tordoya","doi":"10.1016/j.rcreue.2024.11.007","DOIUrl":"10.1016/j.rcreue.2024.11.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Lupus nephropathy (LN) is a chronic inflammatory process, characterized by the activation of T cells and high levels of various cytokines, such as MCP-1 at the level of the renal glomerulus and the interstitial tubule. MCP-1 is a chemoattractant of monocytes and lymphocytes, it is responsible for the infiltration of leukocytes in the kidney, which is why MCP-1 levels in urine of patients with LN correlate with the active form of the disease.</div></div><div><h3>Objective</h3><div>The present study aims to evaluate the expression levels of MCP-1 in patients with LN and to correlate their urinary levels with serum autoimmunity markers.</div></div><div><h3>Material and methods</h3><div>Our study is of the case-control type, where the groups were made up of 112 patients diagnosed with SLE or LN, and 28 apparently healthy people with no clinical or family history of autoimmune diseases, respectively. MCP-1 expression levels were estimated using qRT-PCR. In addition, clinical parameters and serum levels were evaluated (anti-ds-DNA, anti-nucleosome, anti-C1q antibodies, β2-microglobulin levels, and C3 and C4 complement fraction). Finally, clinical, and molecular data were correlated.</div></div><div><h3>Results</h3><div>Our study included 39 patients with active SLE (median 36 years), 32 with active LN (median 32.5 years), 28 with inactive SLE (median 41.5 years), 13 with inactive LN (median 38 years), and 28 control patients (median 28.5 years). The comparison of MCP-1 expression levels between patients with active LN and active SLE did not show statistically significant values (<em>p</em> &gt; 0.05). Likewise, a statistically significant correlation was observed between the expression levels of MCP-1 with the levels of anti-C1q (<em>r</em> = 0.255 <em>p</em> &lt; 0.025); however, no correlation was found with the other markers.</div></div><div><h3>Conclusion</h3><div>The use of MCP-1 expression levels in the Bolivian population would not be a useful biomarker to evaluate Lupus Nephropathy. However, the anti-C1q biomarker is suggested as a serological marker for monitoring the disease.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 49-55"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculosis risk in immunosuppressed patients: Revisiting an old acquaintance","authors":"Jorge Alberto Cortés","doi":"10.1016/j.rcreue.2024.12.003","DOIUrl":"10.1016/j.rcreue.2024.12.003","url":null,"abstract":"","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of latent tuberculosis by tuberculin booster in patients with immunosuppressive treatment","authors":"Luis Javier Cajas ,&nbsp;María Carolina Torres ,&nbsp;Mayelin Fernanda Ceballos","doi":"10.1016/j.rcreue.2025.02.001","DOIUrl":"10.1016/j.rcreue.2025.02.001","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>One-third of the world's population has latent tuberculosis. Because it can be reactivated by immunosuppressive treatments, screening is suggested. In Colombia, the tuberculin test with the booster is recommended in this population because of the risk of false negative results and anergy caused by treatments. Currently, the number of patients detected with this second test is unknown, so the primary objective is to determine the percentage of additional positive detections.</div></div><div><h3>Materials and methods</h3><div>From 2017 to 2022, a cross-sectional, analytical study was conducted on a group of patients from a rheumatology service who had a tuberculin test and a booster within a year to check for latent tuberculosis. Over the course of a year and three weeks, we looked at the number of patients whose booster tests showed new findings. A study was conducted to see if there were any differences in treatment based on the first tuberculin result.</div></div><div><h3>Results</h3><div>A tuberculin test was performed on 674 subjects, of whom 496 were immunosuppressed. From the 382 whose test was negative, 191 and 74 booster tests were performed within a year and three weeks; 8 (4.1%) and 3 (3.6%) were positive, respectively. When evaluating the differences in treatments between the groups with a positive and negative first tuberculin test, significant differences were found. Use of prednisolone at 5<!--> <!-->mg or more per day (<em>p</em> <!-->=<!--> <!-->.02) and three immunosuppressants (<em>p</em> <!-->=<!--> <!-->.005) was more frequent in negative tuberculin tests.</div></div><div><h3>Conclusions</h3><div>It can be said that the booster test raises the number of people with latent tuberculosis by 4%. More use of prednisolone at 5<!--> <!-->mg/day or three immunosuppressants in the group with the negative tuberculin test was found to be statistically significant.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 10-15"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of motor skill in patients with juvenile idiopathic arthritis: A cross sectional study","authors":"Sinem Yenil ,&nbsp;Elif Gur Kabul ,&nbsp;Bilge Basakci Calik ,&nbsp;Gulsah Kilbas ,&nbsp;Selcuk Yuksel","doi":"10.1016/j.rcreue.2025.02.003","DOIUrl":"10.1016/j.rcreue.2025.02.003","url":null,"abstract":"<div><h3>Introduction</h3><div>The inflammatory process of Juvenile Idiopathic Arthritis (JIA) is associated comorbidities. The JIA patients can fall behind their healthy peers, and motor and functional skills can reduce.</div></div><div><h3>Objectives</h3><div>The primary aim is to compare the motor skills of JIA patients with healthy controls. The secondary aim is to determine whether disease activity affects patients with JIA.</div></div><div><h3>Materials and methods</h3><div>Fifteen patients with JIA and 15 healthy controls were included in the study. Motor skills were evaluated with Bruininks-Oseretsky Test of Motor Proficiency Second Edition Short Form (BOT-2 SF) in patients with JIA and healthy controls. BOT-2 SF measures four motor area composites with eight subtests. Disease activity was evaluated with Juvenile Arthritis Disease Activity Score-27 (JADAS-27), disability level with Childhood Health Assessment Questionnaire Disability Index (CHAQ-DI), and disease-related quality of life with Pediatric Quality of Life Inventory (PedsQL) 3.0 Arthritis Module for JIA. According to disease activity, patients with JIA were divided into two groups as remission and active.</div></div><div><h3>Results</h3><div>The patients with JIA had significantly lower scores in the total and four motor area of BOT-2 SF compared to healthy controls (<em>p</em> <!-->&lt;<!--> <!-->.05). When the remission and active groups were compared, there was no difference in the total and four motor area of BOT-2 SF, CHAQ-DI, or PedsQL (<em>p</em> <!-->&gt;<!--> <!-->.05).</div></div><div><h3>Conclusion</h3><div>The motor skills of patients with JIA are lower than their healthy peers, and their motor skills, quality of life, and disability did not make a difference between the remission and active period.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 36-42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histological findings and complications in patients with salivary gland biopsy in two institutions of Medellín, Colombia a descriptive study","authors":"Luz Adriana Gómez-Ramírez ,&nbsp;Laura Betancur-Gómez ,&nbsp;Estefanía Tabares-Ramírez ,&nbsp;Sofía Villada-Montoya ,&nbsp;Libia María Rodríguez-Padilla ,&nbsp;María Fernanda Álvarez-Barreneche ,&nbsp;Carlos Jaime Velásquez-Franco ,&nbsp;Miguel Antonio Mesa-Navas ,&nbsp;Marcela Posada-Velásquez","doi":"10.1016/j.rcreue.2024.11.001","DOIUrl":"10.1016/j.rcreue.2024.11.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Salivary gland biopsy is the gold standard for the diagnosis of Sjogren’s syndrome. There are several approaches for the realization of the biopsy, being generally used an approach to the mucosa with the use of various instruments and incisions that vary in length, passing through trucut biopsy to scraping with needle.</div></div><div><h3>Materials and methods</h3><div>We conducted a descriptive study that included adult patients undergoing salivary gland biopsy between 2017 and 2022. Medical records and salivary gland biopsy reports were used to collect information and registered in the Magpi platform. Sociodemographic, clinical, and histopathological variables were recorded. The qualitative variables were expressed in absolute and relative frequencies; the quantitative ones were by median and interquartile range. Seventy-two biopsies were included.</div></div><div><h3>Results</h3><div>Regarding demographic characteristics, 87,5% were women with a median age of 52 years. The biopsy characteristics showed that 70 (97,2%) corresponded to a representative sample. Twenty-seven (38,5%) biopsies showed lymphocytic infiltration and reported a classification system, of which the most used one was the Chisholm Mason used in 18 (66,6%) of such biopsies. Complications were present in four (5,7%) patients.</div></div><div><h3>Conclusions</h3><div>Despite the recommendation of using Focus Score for classification criteria, the Chisholm Mason system is still the most widely used. The present technique is a safe and effective for the realization of minor salivary gland biopsy.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 1","pages":"Pages 3-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growing up with juvenile idiopathic arthritis: Social issues","authors":"Sirine Miri ,&nbsp;Hanene Lassoued Ferjani ,&nbsp;Dorra Ben Nessib ,&nbsp;Fatma Majdoub ,&nbsp;Dhia Kaffel ,&nbsp;Kaouther Maatallah ,&nbsp;Wafa Hamdi","doi":"10.1016/j.rcreue.2023.08.003","DOIUrl":"10.1016/j.rcreue.2023.08.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Juvenile idiopathic arthritis is a chronic inflammatory condition interfering with daily activities, social integration, and school attendance in children because of pain and joint inflammation during disease flares. Online resources might help children with JIA improve their social interactions and enhance their knowledge about their disease and the available therapeutic strategies.</div></div><div><h3>Objective</h3><div>This study aims to reveal the social issues encountered by teenagers prone to JIA and determine their perception of the impact of social media on their daily life.</div></div><div><h3>Material and methods</h3><div>We conducted this study using inductive qualitative methods to describe the sociocultural perception and experience of adolescents with JIA aged between 8 and 16 years.</div></div><div><h3>Results</h3><div>Individual interviews were held with 22 adolescents diagnosed with JIA. Fifty-two percent felt like outcasts and rejected by their peers because of their illness. Most of the participants expressed a need for their friends to be informed about their JIA diagnosis. Twenty-two-point-seven percent stated that they played sports for more than 5<!--> <!-->h a week. A total of 31.8% found their physical performance was not affected by their disease. Ninety-seven of the participants confirmed that they use social media on average 3<!--> <!-->h a day. YouTube and Facebook were ranked respectively as the first and the second preferred platforms. Seventeen percent of the children viewed these platforms as positive and helpful in dealing with JIA, especially by taking their minds off the pain, dealing with the stress resulting from the lack of mobility, and facilitating interactions with others.</div></div><div><h3>Conclusion</h3><div>Social integration in children with JIA is still challenging. Social media is helpful in managing JIA and improving social interactions, and in gaining useful information.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 452-456"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and implementation of clinical care centres for spondyloarthritis. A benchmark care and disease model in chronic pathologies","authors":"Wilson Bautista-Molano ,&nbsp;Paul Méndez-Patarroyo ,&nbsp;Helbert Orlando Arévalo Roa ,&nbsp;Gerardo Quintana-López","doi":"10.1016/j.rcreue.2024.08.003","DOIUrl":"10.1016/j.rcreue.2024.08.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Spondyloarthritis (SpA) is a musculoskeletal disease presenting with phenotypic clinical manifestations, integrating a set of interrelated inflammatory conditions, which share immunogenetic, epidemiological, and therapeutic characteristics.</div></div><div><h3>Objective</h3><div>to do a reflection exercise through the experience of designing and implementing a clinical care center for spondyloarthropathies, from the administrative and clinical perspective to the implications in decision making and impact on the different indicators related to efficiencies and safety of the services included in the model.</div></div><div><h3>Results</h3><div>In clinical practice, the reality of the care process in patients diagnosed with SpA represents an area of ​​opportunity in multiple aspects. The fragmentation of clinical care and the heterogeneous flow of the patient in the care pathway, are associated with suboptimal and undesired clinical outcomes. Several aspects highlight the reality of patients with SpA in the national scenario, which -to a certain extent- could reflect what is observed in other Latin American countries. SpA represents a very significant burden for society and for individuals affected by this condition. Comprehensive assessment of the burden of disease from the perspective of the clinician and the patient is important, in order to support decisions related to treatment and comprehensive management of this condition. The improvement in health outcomes and the reduction in the cost of chronic inflammatory diseases, such as SpA, are the main advantages of implementing a care model in specialized centres integrating a multidisciplinary team.</div></div><div><h3>Conclusion</h3><div>This is an opportunity to include the perspective of individuals affected by this condition, seeking integration between an informed patient and a highly qualified multidisciplinary care team in the comprehensive management of patients with SpA.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 511-516"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadequate sleep as a limiting factor in achieving remission in patients with rheumatoid arthritis","authors":"Amarilis J. Pérez De Jesus ,&nbsp;Nahir S. Pérez Soto ,&nbsp;Miguel A. Vázquez Padua","doi":"10.1016/j.rcreue.2023.05.005","DOIUrl":"10.1016/j.rcreue.2023.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Good sleep has a restorative effect at the cellular level and helps maintain the body's homeostasis.</div></div><div><h3>Objectives</h3><div>Given our clinical experiences, we propose that sleep quality should be evaluated in patients with rheumatoid arthritis. Poor sleep quality should be considered as a factor that may impact clinical outcomes in patients with rheumatoid arthritis.</div></div><div><h3>Materials and methods</h3><div>We researched medical literature on clinical and physiological pathways associated with sleep quality.</div></div><div><h3>Results</h3><div>There is evidence that interleukin-6 and tumor necrosis factor have a role in inflammatory and immune imbalance as well as in sleep disturbance in patients with rheumatoid arthritis, which leads to the chronic inflammatory process seen in these patients. Most patients with rheumatoid arthritis report sleep problems, be it insomnia or other complaints of non-refreshing sleep. Lack of sleep or poor sleep patterns in these patients further compromise their quality of life. In patients with RA, aetiologies such as restless leg syndrome (RLS), sleep apnoea syndrome, and Temporomandibular Joint Dysfunction (TMJ) syndromes might contribute to sleep disturbances. This lack of restful sleep might limit our goal, as treating physicians, to achieve remission states in these patients.</div></div><div><h3>Conclusions</h3><div>It is our opinion that sleep quality evaluation must be addressed, monitored, and treated as part of the management of patients with RA. Bad sleep adds an additional burden to disease activity in patients with RA, besides, it limits patients’ possibility of achieving disease remission.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"31 4","pages":"Pages 517-522"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}