The genus Rickettsia in the order Rickettsiales (Alphaproteobacteria) consists of gram-negative obligate intracellular bacteria that infect a wide range of hosts. Epidemiological studies on the occurrence of Rickettsia spp. and their associated tick vectors are essential to understand their distribution, host range, and transmission mechanisms in nature. This is particularly relevant within the One Health framework, which emphasizes the interconnectedness of animal, human, and environmental health.
Methods
To investigate the presence of Rickettsia spp. in dogs and their ticks in Malawi, a molecular survey was conducted. A total of 209 dog blood and 259 tick samples of the species Haemaphysalis elliptica (n = 16) and Rhipicephalus linnaei (n = 243) were screened using real-time quantitative PCR (qPCR) targeting the citrate synthase (gltA) gene. Positive samples were further characterized via the conventional PCR and Sanger sequencing of gltA and the outer membrane protein A (ompA) genes.
Results
Rickettsia DNA was not detected in any dog samples. However, the detection rates in R. linnaei and H. elliptica were 2.5 % (n = 6) and 6.3 % (n = 1), respectively. The obtained sequences showed 100 % identity with Rickettsia conorii subsp. conorii (n = 4), 99 %–100 % with Rickettsia massiliae (n = 2), and 100 % with Rickettsia rhipicephali (n = 1). Phylogenetic analysis clustered these sequences with the corresponding sequences of R. conorii subsp. conorii, R. massiliae, and R. rhipicephali reported from other countries in both gltA and ompA gene-based phylogenetic trees. The detection of R. massiliae and R. rhipicephali in southern Africa suggests expansion of the geographical distribution of these potentially zoonotic Rickettsia species.
Conclusion
This is the first report of Rickettsia species detection in ticks collected from dogs in Malawi. The findings highlight the need for further surveillance, including humans and other animals, to better assess the public and veterinary health risks. Public engagement is needed to raise awareness on the role of dogs and their ticks in the transmission of Rickettsia within the One Health approach.
{"title":"Investigation of potentially zoonotic Rickettsia species in dogs and their attached ticks in Malawi through the lens of One Health","authors":"Elisha Chatanga , Henson Kainga , John Kothowa , Michael Luwe , Richard Ssuna , Tinotenda Razemba , Laston Chimaliro , Naoki Hayashi , Yuki Ohsugi , Yongjin Qiu , Kyoko Hayashida , Nariaki Nonaka , Ryo Nakao","doi":"10.1016/j.soh.2025.100122","DOIUrl":"10.1016/j.soh.2025.100122","url":null,"abstract":"<div><h3>Background</h3><div>The genus <em>Rickettsia</em> in the order Rickettsiales (Alphaproteobacteria) consists of gram-negative obligate intracellular bacteria that infect a wide range of hosts. Epidemiological studies on the occurrence of <em>Rickettsia</em> spp. and their associated tick vectors are essential to understand their distribution, host range, and transmission mechanisms in nature. This is particularly relevant within the One Health framework, which emphasizes the interconnectedness of animal, human, and environmental health.</div></div><div><h3>Methods</h3><div>To investigate the presence of <em>Rickettsia</em> spp. in dogs and their ticks in Malawi, a molecular survey was conducted. A total of 209 dog blood and 259 tick samples of the species <em>Haemaphysalis elliptica</em> (<em>n</em> = 16) and <em>Rhipicephalus linnaei</em> (<em>n</em> = 243) were screened using real-time quantitative PCR (qPCR) targeting the citrate synthase (<em>gltA</em>) gene. Positive samples were further characterized via the conventional PCR and Sanger sequencing of <em>gltA</em> and the outer membrane protein A (<em>ompA</em>) genes.</div></div><div><h3>Results</h3><div><em>Rickettsia</em> DNA was not detected in any dog samples. However, the detection rates in <em>R</em>. <em>linnaei</em> and <em>H. elliptica</em> were 2.5 % (<em>n</em> = 6) and 6.3 % (<em>n</em> = 1), respectively. The obtained sequences showed 100 % identity with <em>Rickettsia conorii</em> subsp. <em>conorii</em> (<em>n</em> = 4), 99 %–100 % with <em>Rickettsia massiliae</em> (<em>n</em> = 2), and 100 % with <em>Rickettsia rhipicephali</em> (<em>n</em> = 1). Phylogenetic analysis clustered these sequences with the corresponding sequences of <em>R</em>. <em>conorii</em> subsp. <em>conorii</em>, <em>R</em>. <em>massiliae</em>, and <em>R</em>. <em>rhipicephali</em> reported from other countries in both <em>gltA</em> and <em>ompA</em> gene-based phylogenetic trees. The detection of <em>R</em>. <em>massiliae</em> and <em>R</em>. <em>rhipicephali</em> in southern Africa suggests expansion of the geographical distribution of these potentially zoonotic <em>Rickettsia</em> species.</div></div><div><h3>Conclusion</h3><div>This is the first report of <em>Rickettsia</em> species detection in ticks collected from dogs in Malawi. The findings highlight the need for further surveillance, including humans and other animals, to better assess the public and veterinary health risks. Public engagement is needed to raise awareness on the role of dogs and their ticks in the transmission of <em>Rickettsia</em> within the One Health approach.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2024.100100
Amir Hossain , Md. Abdul Monem , Mamunur Rahman , Rashadur Raza
Mpox, formerly referred to as monkeypox, is a viral disease endemic to central Africa, resulting from the monkeypox virus (MPXV). This study provides a current overview of the Mpox epidemic as of 2024, emphasizing significant developments and epidemiological trends. The World Health Organization (WHO) initially designated a clade Ⅱb outbreak as a global health emergency in May 2022, which was subsequently managed through vaccination and public health interventions by May 2023. In September 2023, a resurgence of cladeⅠ in the Democratic Republic of the Congo (DRC) resulted in a 160 % increase in cases by 2024. The WHO declared this increase a public health emergency of international concern (PHEIC) in August 2024. The outbreak timeline indicates substantial rises in cases and fatalities, especially among children under 15 in the DRC. Regional analysis reveals that the European Region initially recorded the highest incidence of cases and fatalities. In contrast, regions including African Region (AFRO), Eastern Mediterranean Region (EMRO), South-East Asia Region (SEARO), and Western Pacific Region (WPRO) exhibited a rise in cases, indicating a potential spread or resurgence of the health event. Gender disparities in transmission pathways were apparent, with males exhibiting higher case numbers, particularly via person-to-person contact. The research highlights the necessity of ongoing surveillance, global collaboration, and focused public health measures. The discourse addresses obstacles in vaccine distribution and the necessity for emergency use authorizations, highlighting the imperativeness for adaptive strategies in public health management. This extensive update offers critical insights into the present condition of the Mpox epidemic and the necessary measures to mitigate its proliferation.
{"title":"Mpox (monkeypox): a comprehensive updated of current epidemic evidence","authors":"Amir Hossain , Md. Abdul Monem , Mamunur Rahman , Rashadur Raza","doi":"10.1016/j.soh.2024.100100","DOIUrl":"10.1016/j.soh.2024.100100","url":null,"abstract":"<div><div>Mpox, formerly referred to as monkeypox, is a viral disease endemic to central Africa, resulting from the monkeypox virus (MPXV). This study provides a current overview of the Mpox epidemic as of 2024, emphasizing significant developments and epidemiological trends. The World Health Organization (WHO) initially designated a clade Ⅱb outbreak as a global health emergency in May 2022, which was subsequently managed through vaccination and public health interventions by May 2023. In September 2023, a resurgence of cladeⅠ in the Democratic Republic of the Congo (DRC) resulted in a 160 % increase in cases by 2024. The WHO declared this increase a public health emergency of international concern (PHEIC) in August 2024. The outbreak timeline indicates substantial rises in cases and fatalities, especially among children under 15 in the DRC. Regional analysis reveals that the European Region initially recorded the highest incidence of cases and fatalities. In contrast, regions including African Region (AFRO), Eastern Mediterranean Region (EMRO), South-East Asia Region (SEARO), and Western Pacific Region (WPRO) exhibited a rise in cases, indicating a potential spread or resurgence of the health event. Gender disparities in transmission pathways were apparent, with males exhibiting higher case numbers, particularly via person-to-person contact. The research highlights the necessity of ongoing surveillance, global collaboration, and focused public health measures. The discourse addresses obstacles in vaccine distribution and the necessity for emergency use authorizations, highlighting the imperativeness for adaptive strategies in public health management. This extensive update offers critical insights into the present condition of the Mpox epidemic and the necessary measures to mitigate its proliferation.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2025.100131
Yue Suo , Kemiao Zhang , Jiaxin Zhao , Jingfei Lyu , Chi Zhang , Zeyu Tan , Gongming Zhao , Yingyao Chen
One Health approaches integrating human, animal, and environmental health are critical for addressing complex public health challenges, yet effective implementation requires robust technological innovation and cross-sectoral collaboration. This paper delves into the implementation and technological innovation of One Health in China, highlighting its significance from a technology assessment perspective. China has made marked progress in applying One Health technologies across domains including emerging infectious disease management, food safety, and antimicrobial resistance control. However, hinderance remains in developing an integrated system for wider technology dissemination. We focus on four main categories of One Health technologies (molecular technologies, geospatial technologies, risk monitoring and surveillance, and artificial intelligence and big data) to offer insights into their benefits, drawbacks, factors for successful implementation, scaling and governance strategies that both facilitate and hinder technology integration. Despite China's accomplishments, challenges remain in cross-sectoral integration, data sharing, and governance. Hence, we propose policy enhancement on the adoption and scaling of One Health technologies in China, aiming to bridge gaps in data integration and collaboration and strengthen governance frameworks.
{"title":"Advancing One Health implementation and technological innovation in China: a technology assessment approach","authors":"Yue Suo , Kemiao Zhang , Jiaxin Zhao , Jingfei Lyu , Chi Zhang , Zeyu Tan , Gongming Zhao , Yingyao Chen","doi":"10.1016/j.soh.2025.100131","DOIUrl":"10.1016/j.soh.2025.100131","url":null,"abstract":"<div><div>One Health approaches integrating human, animal, and environmental health are critical for addressing complex public health challenges, yet effective implementation requires robust technological innovation and cross-sectoral collaboration. This paper delves into the implementation and technological innovation of One Health in China, highlighting its significance from a technology assessment perspective. China has made marked progress in applying One Health technologies across domains including emerging infectious disease management, food safety, and antimicrobial resistance control. However, hinderance remains in developing an integrated system for wider technology dissemination. We focus on four main categories of One Health technologies (molecular technologies, geospatial technologies, risk monitoring and surveillance, and artificial intelligence and big data) to offer insights into their benefits, drawbacks, factors for successful implementation, scaling and governance strategies that both facilitate and hinder technology integration. Despite China's accomplishments, challenges remain in cross-sectoral integration, data sharing, and governance. Hence, we propose policy enhancement on the adoption and scaling of One Health technologies in China, aiming to bridge gaps in data integration and collaboration and strengthen governance frameworks.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145465238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2025.100125
Shijie Yang , Yuancheng Yang , Xuenian Xu , Chenqing Sun , Xiaojuan Zhang , Fan Li , Jianhong Hu , Baolin Zhong , Liying Wang , Ying Wang , Shuai Han , Chuizhao Xue , Xu Wang , Baixue Liu , Chun Fang , Guoxiang Kui , Zonglin Shen , Yu Feng , Shizhu Li , Ning Xiao , Yuhua Li
Background
Echinococcosis constitutes a major zoonotic parasitic disease with profound public health and socioeconomic implications. Dog deworming remains a cornerstone intervention endorsed by World Health Organization. This study comparatively assessed automated vs. manual praziquantel (PZQ) bait delivery systems for dog echinococcosis control.
Methods
A prospective, randomized, double-blinded field trial employing a One Health framework was conducted in Tianzhu Zangzu Zizhixian, China—a cystic echinococcosis endemic region. Township-level cluster randomization allocated dogs to smart collar deworming group (SCDG) with monthly automated PZQ delivery and manual deworming group (MDG) with conventional bait administration. Intervention assignment remained masked between groups. Laboratory personnel were blinded during fecal antigen analysis using enzyme linked immunosorbent assay (ELISA). Generalized Estimating Equations (GEE) evaluated efficacy via odds ratios (ORs) over 24 months, SPSS software (version 27.0) was used for data processing. Metrics included parasitological outcomes, deworming frequency, collar deployment and recovery rates.
Results
From June 2021 to July 2023, 1920 dogs (800 from SCDG, 1120 from MDG) were enrolled with owner consent. Among the 5119 fecal samples analyzed (2320 from SCDG, 2799 from MDG), 33 were antigen-positive (8 from SCDG, 25 from MDG). Baseline positivity showed no intergroup difference (SCDG: 0.8 % [6/792] vs. MDG: 1.2 % [13/1099], P = 0.36). At 24 months, SCDG achieved 0 % positivity (0/661) while MDG's was 0.6 % (5/789). Smart collars conferred significant protection (OR = 0.432, 95 % confidence interval [CI]: 0.194–0.959, P < 0.0001)—equivalent to 56.8 % infection risk reduction. At 12 months, the recycling rate and integrity rate of smart collars were 83.3 % (666/800) and 74.3 % (495/666), respectively; and the proportion of dogs dewormed 6–12 times per year was 86.7 % (577/666). At 24 months, the recycling rate and integrity rate of smart collars were up to 93.6 % (749/800, χ2 = 42.106, P < 0.001) and 94.1 % (705/749, χ2 = 107.269, P < 0.001), respectively. During this period, 91.6 % (1202/1312) of dogs received deworming 6–12 times per year. In 2023, a total of 647 smart collars were distributed, with the recycling rate and integrity rate of 99.8 % (646/647) and 96.4 % (623/646), respectively. The proportion of dogs dewormed 6–12 times per year increased to 96.6 % (625/646, χ2 = 34.969, P < 0.001).
Conclusions
Field deployment of smart collars proves operationally viable, sustainably enhancing deworming frequency while reducing dog infection rates more effectively than manual methods. The 56.8 % protective effect advancement mitigates environmental eg
棘球蚴病是一种主要的人畜共患寄生虫病，具有深远的公共卫生和社会经济影响。为狗驱虫仍然是世界卫生组织认可的一项基础干预措施。本研究比较评估了自动和手动吡喹酮（PZQ）饵剂递送系统对犬棘球蚴病的控制效果。方法采用“一个健康”框架，在中国包虫病流行地区天竺藏祖紫治县进行前瞻性、随机、双盲实地试验。按乡级随机分组，将犬分为智能项圈驱虫组（SCDG）和人工驱虫组（MDG），前者每月自动给药PZQ，后者采用常规给药方式。干预任务在组间仍然被掩盖。使用酶联免疫吸附试验（ELISA）进行粪便抗原分析时，实验室人员采用盲法。广义估计方程（GEE）通过比值比（ORs）评估24个月的疗效，使用SPSS软件（版本27.0）进行数据处理。指标包括寄生虫学结果、驱虫频率、项圈部署和回收率。结果2021年6月至2023年7月，经饲主同意，共入组犬1920只，其中SCDG犬800只，MDG犬1120只。在5119份粪便样本中（SCDG 2320份，MDG 2799份），抗原阳性33份（SCDG 8份，MDG 25份）。基线阳性无组间差异（SCDG: 0.8% [6/792] vs MDG: 1.2% [13/1099], P = 0.36）。在24个月时，SCDG的阳性率为0%(0/661)，而MDG的阳性率为0.6%（5/789）。智能项圈具有显著的保护作用（OR = 0.432, 95%可信区间[CI]: 0.194-0.959, P < 0.0001），相当于降低56.8%的感染风险。12个月时，智能领圈回收率为83.3%(666/800)，完好率为74.3% (495/666)；年脱虫6 ~ 12次占86.7%（577/666）。24个月时，智能项圈回收率为93.6% (749/800,χ2 = 42.106, P < 0.001)，完好率为94.1% （705/749,χ2 = 107.269, P < 0.001）。在此期间，91.6%（1202/1312）的狗每年接受6-12次驱虫。2023年共发放智能项圈647个，回收率为99.8%(646/647)，完好率为96.4%（623/646）。每年脱虫6 ~ 12次的比例增加到96.6% （625/646,χ2 = 34.969, P < 0.001）。结论现场部署智能项圈在操作上是可行的，可持续提高驱虫频率，同时比人工方法更有效地降低狗的感染率。56.8%的保护效果提升减轻了环境鸡蛋污染，从而降低了人畜共患病的传播风险。
{"title":"Dog deworming by smart collar: a 24-month field evaluation from a One Health prospective, randomized, double masked trial","authors":"Shijie Yang , Yuancheng Yang , Xuenian Xu , Chenqing Sun , Xiaojuan Zhang , Fan Li , Jianhong Hu , Baolin Zhong , Liying Wang , Ying Wang , Shuai Han , Chuizhao Xue , Xu Wang , Baixue Liu , Chun Fang , Guoxiang Kui , Zonglin Shen , Yu Feng , Shizhu Li , Ning Xiao , Yuhua Li","doi":"10.1016/j.soh.2025.100125","DOIUrl":"10.1016/j.soh.2025.100125","url":null,"abstract":"<div><h3>Background</h3><div>Echinococcosis constitutes a major zoonotic parasitic disease with profound public health and socioeconomic implications. Dog deworming remains a cornerstone intervention endorsed by World Health Organization. This study comparatively assessed automated vs. manual praziquantel (PZQ) bait delivery systems for dog echinococcosis control.</div></div><div><h3>Methods</h3><div>A prospective, randomized, double-blinded field trial employing a One Health framework was conducted in Tianzhu Zangzu Zizhixian, China—a cystic echinococcosis endemic region. Township-level cluster randomization allocated dogs to smart collar deworming group (SCDG) with monthly automated PZQ delivery and manual deworming group (MDG) with conventional bait administration. Intervention assignment remained masked between groups. Laboratory personnel were blinded during fecal antigen analysis using enzyme linked immunosorbent assay (ELISA). Generalized Estimating Equations (GEE) evaluated efficacy via odds ratios (<em>OR</em>s) over 24 months, <em>SPSS</em> software (version 27.0) was used for data processing. Metrics included parasitological outcomes, deworming frequency, collar deployment and recovery rates.</div></div><div><h3>Results</h3><div>From June 2021 to July 2023, 1920 dogs (800 from SCDG, 1120 from MDG) were enrolled with owner consent. Among the 5119 fecal samples analyzed (2320 from SCDG, 2799 from MDG), 33 were antigen-positive (8 from SCDG, 25 from MDG). Baseline positivity showed no intergroup difference (SCDG: 0.8 % [6/792] vs. MDG: 1.2 % [13/1099], <em>P</em> = 0.36). At 24 months, SCDG achieved 0 % positivity (0/661) while MDG's was 0.6 % (5/789). Smart collars conferred significant protection (<em>OR</em> = 0.432, 95 % confidence interval [<em>CI</em>]: 0.194–0.959, <em>P</em> < 0.0001)—equivalent to 56.8 % infection risk reduction. At 12 months, the recycling rate and integrity rate of smart collars were 83.3 % (666/800) and 74.3 % (495/666), respectively; and the proportion of dogs dewormed 6–12 times per year was 86.7 % (577/666). At 24 months, the recycling rate and integrity rate of smart collars were up to 93.6 % (749/800, <em>χ</em><sup>2</sup> = 42.106, <em>P</em> < 0.001) and 94.1 % (705/749, <em>χ</em><sup>2</sup> = 107.269, <em>P</em> < 0.001), respectively. During this period, 91.6 % (1202/1312) of dogs received deworming 6–12 times per year. In 2023, a total of 647 smart collars were distributed, with the recycling rate and integrity rate of 99.8 % (646/647) and 96.4 % (623/646), respectively. The proportion of dogs dewormed 6–12 times per year increased to 96.6 % (625/646, <em>χ</em><sup>2</sup> = 34.969, <em>P</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>Field deployment of smart collars proves operationally viable, sustainably enhancing deworming frequency while reducing dog infection rates more effectively than manual methods. The 56.8 % protective effect advancement mitigates environmental eg","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2025.100104
Ne Qiang , Tianyun Li , Lijun Jia , Zelin Zhu , Xinyu Feng , Jinjun Ran , Xiaoxi Zhang , Lefei Han
Background
Emerging infectious diseases (EIDs) pose significant public health challenges due to increasing interactions between humans, animals, and the environment. The One Health framework, an interdisciplinary and collaborative approach, plays a critical role in the risk assessment of EIDs. The study aims to systematically review the risk assessment of EIDs in China under the One Health framework, covering policy support, monitoring and assessment systems, and implementation methods.
Methods
Relevant literature and official documents between 1997 and 2024 were retrieved from Web of Science, PubMed, Scopus, China National Knowledge Infrastructure, Wan Fang, China Science and Technology Journal Database, and government websites. Data were synthesized to analyze progress, challenges, and gaps.
Results
There were 43 academic studies and 31 official documents included in this review. The study found that risk assessment systems existed across human, animal, and environmental health sectors in China, and the government was advancing intelligent monitoring and fostering inter-departmental cooperation. However, several challenges remain in risk assessment of EIDs, including inadequate monitoring systems for unknown EIDs, limited capacity building for risk assessment in ecosystems and environmental systems, insufficiently detailed risk assessment guidance at the county level, and barriers to cross-sectoral information sharing at the international and county levels.
Conclusion
The findings highlighted the need to enhance risk assessment of EIDs at the local level, expand the scope of disease surveillance including aquatic and wild animals, and strengthen inter-departmental data sharing to improve early warning capabilities under the One Health framework.
由于人类、动物和环境之间的相互作用日益增加，新兴传染病（eid）构成了重大的公共卫生挑战。“同一个健康”框架是一种跨学科和协作的方法，在评估eid风险方面发挥着关键作用。本研究旨在系统回顾“一个健康”框架下中国eid风险评估，包括政策支持、监测和评估体系以及实施方法。方法检索Web of Science、PubMed、Scopus、中国国家知识基础设施、万方、中国科技期刊库和政府网站1997 ~ 2024年的相关文献和官方文件。综合数据分析进展、挑战和差距。结果共纳入学术研究43篇，官方文献31篇。该研究发现，中国的人类、动物和环境卫生部门存在风险评估系统，政府正在推进智能监测并促进部门间合作。然而，在eid风险评估方面仍存在一些挑战，包括未知eid监测系统不足、生态系统和环境系统风险评估能力建设有限、县级风险评估指导不够详细、以及在国际和县级跨部门信息共享方面存在障碍。结论在“同一个健康”框架下，需要加强地方层面的eid风险评估，扩大包括水生动物和野生动物在内的疾病监测范围，加强部门间数据共享，以提高预警能力。
{"title":"Risk assessment of emerging infectious diseases in China under the One Health framework","authors":"Ne Qiang , Tianyun Li , Lijun Jia , Zelin Zhu , Xinyu Feng , Jinjun Ran , Xiaoxi Zhang , Lefei Han","doi":"10.1016/j.soh.2025.100104","DOIUrl":"10.1016/j.soh.2025.100104","url":null,"abstract":"<div><h3>Background</h3><div>Emerging infectious diseases (EIDs) pose significant public health challenges due to increasing interactions between humans, animals, and the environment. The One Health framework, an interdisciplinary and collaborative approach, plays a critical role in the risk assessment of EIDs. The study aims to systematically review the risk assessment of EIDs in China under the One Health framework, covering policy support, monitoring and assessment systems, and implementation methods.</div></div><div><h3>Methods</h3><div>Relevant literature and official documents between 1997 and 2024 were retrieved from Web of Science, PubMed, Scopus, China National Knowledge Infrastructure, Wan Fang, China Science and Technology Journal Database, and government websites. Data were synthesized to analyze progress, challenges, and gaps.</div></div><div><h3>Results</h3><div>There were 43 academic studies and 31 official documents included in this review. The study found that risk assessment systems existed across human, animal, and environmental health sectors in China, and the government was advancing intelligent monitoring and fostering inter-departmental cooperation. However, several challenges remain in risk assessment of EIDs, including inadequate monitoring systems for unknown EIDs, limited capacity building for risk assessment in ecosystems and environmental systems, insufficiently detailed risk assessment guidance at the county level, and barriers to cross-sectoral information sharing at the international and county levels.</div></div><div><h3>Conclusion</h3><div>The findings highlighted the need to enhance risk assessment of EIDs at the local level, expand the scope of disease surveillance including aquatic and wild animals, and strengthen inter-departmental data sharing to improve early warning capabilities under the One Health framework.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100104"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2025.100109
Mikidadi Muhanga
Globally, human, livestock, and wildlife interactions have been reported to result in innumerable forms of conflict and consequences. The most notable consequences are on the environment and human health, among others. The least developed countries, Tanzania inclusive, due to their bio-geographical and social characteristics, are mostly reported to register such consequences, which have sometimes led to zoonotic diseases due to the existence of risk factors. The factors include the growth of the human population, absence of infrastructural capacity, and skilled manpower to effectively deal with disease outbreaks and livestock keeping associated lifestyles. This article employs a documentary research method to analyse the human-wildlife conflict (HWC) and its consequences in Tanzania. It further assesses the potential of the One Health approach to curb the consequences of HWC following the introduction of One Health Strategic Plan (2015–2020). This article, therefore, analyses the potential for One Health approach to minimize the undesirable impacts of human, livestock, and wildlife interactions on health. This approach underscores the need for collaborative working efforts involving human, livestock, wildlife, and environmental health professionals and the need for a good understanding of the consequences of the interactions towards the realisation of optimum health for people, animals, and our environment.
{"title":"Human-wildlife conflict and its consequences in Tanzania: advocating the use of One Health approach as a mitigation measure","authors":"Mikidadi Muhanga","doi":"10.1016/j.soh.2025.100109","DOIUrl":"10.1016/j.soh.2025.100109","url":null,"abstract":"<div><div>Globally, human, livestock, and wildlife interactions have been reported to result in innumerable forms of conflict and consequences. The most notable consequences are on the environment and human health, among others. The least developed countries, Tanzania inclusive, due to their bio-geographical and social characteristics, are mostly reported to register such consequences, which have sometimes led to zoonotic diseases due to the existence of risk factors. The factors include the growth of the human population, absence of infrastructural capacity, and skilled manpower to effectively deal with disease outbreaks and livestock keeping associated lifestyles. This article employs a documentary research method to analyse the human-wildlife conflict (HWC) and its consequences in Tanzania. It further assesses the potential of the One Health approach to curb the consequences of HWC following the introduction of One Health Strategic Plan (2015–2020). This article, therefore, analyses the potential for One Health approach to minimize the undesirable impacts of human, livestock, and wildlife interactions on health. This approach underscores the need for collaborative working efforts involving human, livestock, wildlife, and environmental health professionals and the need for a good understanding of the consequences of the interactions towards the realisation of optimum health for people, animals, and our environment.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143898533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The journal Science in One Health (SOH) has served as a platform for advancing One Health knowledge and practice since 2022. Guided by the vision of “One World, One Health”, SOH is committed to exploring health issues at the human-animal-environment interface. Over the past three years, SOH has built an ambitious and dynamic editorial board across diverse disciplines, expanding its global influence and establishing itself as a global One Health community of authors and readers. So far, SOH has published 4 volumes, featuring 90 influential articles. Among them, 11 articles have garnered 17–82 citations, and 10 have achieved 2700–12,000 downloads. The third anniversary is considered a significant milestone, which marks a solid foundation for sustained growth. Moving forward, we expect to shape the future of One Health in collaboration with authors, readers, reviewers, and editorial board members of SOH.
{"title":"Celebrating three years of Science in One Health: shaping a transdisciplinary community","authors":"Hanqing Zhao , Lorne Babiuk , Robin Gasser , Yvon Le Maho , Jianguo Xu , Jianzhong Shen , Hualan Chen , Qingming Luo , Jiming Liu , Xiaokui Guo , Junshi Chen , Renhe Zhang , Marcel Tanner , Xiao-Nong Zhou","doi":"10.1016/j.soh.2025.100124","DOIUrl":"10.1016/j.soh.2025.100124","url":null,"abstract":"<div><div>The journal <em>Science in One Health</em> (SOH) has served as a platform for advancing One Health knowledge and practice since 2022. Guided by the vision of “One World, One Health”, SOH is committed to exploring health issues at the human-animal-environment interface. Over the past three years, SOH has built an ambitious and dynamic editorial board across diverse disciplines, expanding its global influence and establishing itself as a global One Health community of authors and readers. So far, SOH has published 4 volumes, featuring 90 influential articles. Among them, 11 articles have garnered 17–82 citations, and 10 have achieved 2700–12,000 downloads. The third anniversary is considered a significant milestone, which marks a solid foundation for sustained growth. Moving forward, we expect to shape the future of One Health in collaboration with authors, readers, reviewers, and editorial board members of SOH.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100124"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2025.100113
Godspower Oke Omokaro
Climate change poses a significant threat to Nigeria's agricultural sector, which is a cornerstone of its economy and food security. The increasing frequency of extreme weather events, erratic rainfall patterns, and rising temperatures have disrupted agricultural productivity, threatening the livelihoods of millions of Nigerians. Through a comprehensive literature review, synthesizing data from peer-reviewed journals, institutional reports, and credible online sources from 2000 to 2023, this study aims to explore the multi-faceted impacts of climate variability on agricultural production, livestock, fisheries, and food security in Nigeria, and to identify effective adaptation strategies to mitigate these impacts. The findings reveal that climate change has significantly disrupted agricultural productivity in Nigeria, with erratic rainfall, rising temperatures, and extreme weather events leading to reduced crop yields, increased pest and disease pressure, and land degradation. Vulnerable crops such as maize, cassava, and rice are particularly affected, while livestock production faces challenges such as heat stress and reduced feed availability. The fisheries sector is also impacted, with shrinking water resources and increasing contamination levels threatening livelihoods. Adaptation strategies, including crop diversification, improved irrigation, and indigenous knowledge practices, offer some resilience but require substantial policy and financial support. The study highlights the urgency of implementing climate-smart agricultural practices, enhancing infrastructure, and promoting public-private partnerships to mitigate climate-induced risks. Recommendations align with the United Nations Sustainable Development Goals (SDGs) 2 (Zero Hunger), 13 (Climate Action), and 15 (Life on Land), emphasizing the need for sustainable agricultural practices, ecosystem preservation, and adaptive policy frameworks to ensure food security and economic stability in Nigeria. This study provides valuable insights into the impacts of climate change on Nigeria's agricultural sector and offers practical recommendations for building resilience and ensuring sustainable food systems. It reveals the importance of collaborative efforts at all levels to address the challenges posed by climate change and safeguard the nation's agricultural heritage for future generations.
{"title":"Multi-impacts of climate change and mitigation strategies in Nigeria: agricultural production and food security","authors":"Godspower Oke Omokaro","doi":"10.1016/j.soh.2025.100113","DOIUrl":"10.1016/j.soh.2025.100113","url":null,"abstract":"<div><div>Climate change poses a significant threat to Nigeria's agricultural sector, which is a cornerstone of its economy and food security. The increasing frequency of extreme weather events, erratic rainfall patterns, and rising temperatures have disrupted agricultural productivity, threatening the livelihoods of millions of Nigerians. Through a comprehensive literature review, synthesizing data from peer-reviewed journals, institutional reports, and credible online sources from 2000 to 2023, this study aims to explore the multi-faceted impacts of climate variability on agricultural production, livestock, fisheries, and food security in Nigeria, and to identify effective adaptation strategies to mitigate these impacts. The findings reveal that climate change has significantly disrupted agricultural productivity in Nigeria, with erratic rainfall, rising temperatures, and extreme weather events leading to reduced crop yields, increased pest and disease pressure, and land degradation. Vulnerable crops such as maize, cassava, and rice are particularly affected, while livestock production faces challenges such as heat stress and reduced feed availability. The fisheries sector is also impacted, with shrinking water resources and increasing contamination levels threatening livelihoods. Adaptation strategies, including crop diversification, improved irrigation, and indigenous knowledge practices, offer some resilience but require substantial policy and financial support. The study highlights the urgency of implementing climate-smart agricultural practices, enhancing infrastructure, and promoting public-private partnerships to mitigate climate-induced risks. Recommendations align with the United Nations Sustainable Development Goals (SDGs) 2 (Zero Hunger), 13 (Climate Action), and 15 (Life on Land), emphasizing the need for sustainable agricultural practices, ecosystem preservation, and adaptive policy frameworks to ensure food security and economic stability in Nigeria. This study provides valuable insights into the impacts of climate change on Nigeria's agricultural sector and offers practical recommendations for building resilience and ensuring sustainable food systems. It reveals the importance of collaborative efforts at all levels to address the challenges posed by climate change and safeguard the nation's agricultural heritage for future generations.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pseudomonas aeruginosa and Acinetobacter baumannii are common nosocomial pathogens in hospital settings. Recently, they have also been found in non-hospital environments, such as poultry farms. While most studies in Ethiopia have focused on these bacteria's antibiotic resistance patterns in hospitals, information regarding their prevalence and resistance in veterinary settings, particularly poultry farms, is limited. This study aimed to assess the prevalence and antibiotic resistance patterns of P. aeruginosa and A. baumannii isolated from chicken droppings on poultry farms.
Methods
A cross-sectional study was conducted from March 2022 to June 2022. A total of 87 poultry farms were included in this study, and pooled chicken dropping samples were collected. The samples were subsequently transferred to buffered peptone water and cultured on MacConkey agar. Species of the isolates were identified via routine biochemical tests, including oxidase, catalase, urease, Simon's citrate, sulfide indole motility medium, triple sugar iron agar and growth at temperatures of 37 °C and 42 °C. The Kirby–Bauer disk diffusion technique was used for antibiotic susceptibility testing. The data were entered into EpiData version 4.6 and then exported to SPSS version 26 for analysis. Fisher's exact test was used to observe an appropriate association between independent variables and the occurrence of isolates. The results are presented in the text, figures and tables.
Results
Among the 87 poultry farms, 41 (47.1 %) were positive for Pseudomonas and Acinetobacter. Among these strains, 24 (27.6 %) P. aeruginosa strains and 13 (14.9 %) A. baumannii strains were recovered. P. aeruginosa showed complete resistance to tetracycline (24, 100.0 %) and trimethoprim-sulfamethoxazole (24, 100.0 %). Additionally, there was a high rate of resistance to ciprofloxacin (13, 54.2 %) and amikacin (12, 50.0 %). Similarly, 13 (100.0 %) A. baumannii isolates were resistant to tetracycline, and 12 (92.3 %) were resistant to trimethoprim-sulfamethoxazole. However, both isolates presented lower resistance rates to piperacillin-tazobactam (4, 9.8 %) and cefepime (7, 17.1 %). Both A. baumannii and P. aeruginosa exhibited multidrug resistance in 10/13 (76.9 %) and 16/24 (66.7 %) of the strains, respectively. The overall prevalence of multidrug resistance in this study was 28/41 (68.3 %).
Conclusion
This study demonstrated that poultry farms may be potential reservoirs for P. aeruginosa and A. baumannii, including antibiotic-resistant strains. This is a significant concern to public health because poultry farmers may be contaminated, increasing their dissemination to the community. Therefore, poultry farmers should improve sanitation and reduc
{"title":"Prevalence and antibiotic resistance patterns of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated from chicken droppings on poultry farms in Gondar city, Northwest Ethiopia","authors":"Mitkie Tigabie , Muluneh Assefa , Yalewayker Gashaw , Azanaw Amare , Aklilu Ambachew , Sirak Biset , Feleke Moges","doi":"10.1016/j.soh.2024.100099","DOIUrl":"10.1016/j.soh.2024.100099","url":null,"abstract":"<div><h3>Background</h3><div><em>Pseudomonas aeruginosa</em> and <em>Acinetobacter baumannii</em> are common nosocomial pathogens in hospital settings. Recently, they have also been found in non-hospital environments, such as poultry farms. While most studies in Ethiopia have focused on these bacteria's antibiotic resistance patterns in hospitals, information regarding their prevalence and resistance in veterinary settings, particularly poultry farms, is limited. This study aimed to assess the prevalence and antibiotic resistance patterns of <em>P. aeruginosa</em> and <em>A. baumannii</em> isolated from chicken droppings on poultry farms.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from March 2022 to June 2022. A total of 87 poultry farms were included in this study, and pooled chicken dropping samples were collected. The samples were subsequently transferred to buffered peptone water and cultured on MacConkey agar. Species of the isolates were identified via routine biochemical tests, including oxidase, catalase, urease, Simon's citrate, sulfide indole motility medium, triple sugar iron agar and growth at temperatures of 37 °C and 42 °C. The Kirby–Bauer disk diffusion technique was used for antibiotic susceptibility testing. The data were entered into <em>EpiData</em> version 4.6 and then exported to <em>SPSS</em> version 26 for analysis. Fisher's exact test was used to observe an appropriate association between independent variables and the occurrence of isolates. The results are presented in the text, figures and tables.</div></div><div><h3>Results</h3><div>Among the 87 poultry farms, 41 (47.1 %) were positive for <em>Pseudomonas</em> and <em>Acinetobacter</em>. Among these strains, 24 (27.6 %) <em>P. aeruginosa</em> strains and 13 (14.9 %) <em>A. baumannii</em> strains were recovered. <em>P. aeruginosa</em> showed complete resistance to tetracycline (24, 100.0 %) and trimethoprim-sulfamethoxazole (24, 100.0 %). Additionally, there was a high rate of resistance to ciprofloxacin (13, 54.2 %) and amikacin (12, 50.0 %). Similarly, 13 (100.0 %) <em>A. baumannii</em> isolates were resistant to tetracycline, and 12 (92.3 %) were resistant to trimethoprim-sulfamethoxazole. However, both isolates presented lower resistance rates to piperacillin-tazobactam (4, 9.8 %) and cefepime (7, 17.1 %). Both <em>A. baumannii</em> and <em>P. aeruginosa</em> exhibited multidrug resistance in 10/13 (76.9 %) and 16/24 (66.7 %) of the strains, respectively. The overall prevalence of multidrug resistance in this study was 28/41 (68.3 %).</div></div><div><h3>Conclusion</h3><div>This study demonstrated that poultry farms may be potential reservoirs for <em>P. aeruginosa</em> and <em>A. baumannii,</em> including antibiotic-resistant strains. This is a significant concern to public health because poultry farmers may be contaminated, increasing their dissemination to the community. Therefore, poultry farmers should improve sanitation and reduc","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143163118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.soh.2024.100102
Chenjia Zhou , Suping Wang , Chenxi Wang , Ne Qiang , Leshan Xiu , Qinqin Hu , Wenyu Wu , Xiaoxi Zhang , Lefei Han , Xinyu Feng , Zelin Zhu , Leilei Shi , Peng Zhang , Kun Yin
Emerging infectious diseases (EIDs) pose a significant threat to public health. Effective surveillance and early warning systems that monitor EIDs in a timely manner are crucial for their control. Given that more than half of EIDs are zoonotic, traditional integrated surveillance systems remain inadequate. Despite recent advances in integrated systems in China, there are few systemic reviews on the integrated surveillance and early warning system of EIDs at community level, particularly under the One Health framework. Here, this systematic review summarizes the current status of surveillance advances in China, including the multi-trigger integrated monitor system. It also highlights the mechanisms for embedding the One Health approach into local policy and practice, while identifying challenges and opportunities for improvement. Additionally, guidelines and recommendations are proposed to optimize the integration of multi-sectoral, multi-level and interdisciplinary cooperation at the human–animal–environment interface.
{"title":"Integrated surveillance and early warning system of emerging infectious diseases in China at community level: current status, gaps and perspectives","authors":"Chenjia Zhou , Suping Wang , Chenxi Wang , Ne Qiang , Leshan Xiu , Qinqin Hu , Wenyu Wu , Xiaoxi Zhang , Lefei Han , Xinyu Feng , Zelin Zhu , Leilei Shi , Peng Zhang , Kun Yin","doi":"10.1016/j.soh.2024.100102","DOIUrl":"10.1016/j.soh.2024.100102","url":null,"abstract":"<div><div>Emerging infectious diseases (EIDs) pose a significant threat to public health. Effective surveillance and early warning systems that monitor EIDs in a timely manner are crucial for their control. Given that more than half of EIDs are zoonotic, traditional integrated surveillance systems remain inadequate. Despite recent advances in integrated systems in China, there are few systemic reviews on the integrated surveillance and early warning system of EIDs at community level, particularly under the One Health framework. Here, this systematic review summarizes the current status of surveillance advances in China, including the multi-trigger integrated monitor system. It also highlights the mechanisms for embedding the One Health approach into local policy and practice, while identifying challenges and opportunities for improvement. Additionally, guidelines and recommendations are proposed to optimize the integration of multi-sectoral, multi-level and interdisciplinary cooperation at the human–animal–environment interface.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143454718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号