Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2020.01.012
Jing Huang, Xiaojian. Shi
{"title":"Glaucoma Secondary to Congenital Ectropion Uveae: A Case Report","authors":"Jing Huang, Xiaojian. Shi","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.012","url":null,"abstract":"","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"13 1","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81998640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2020.01.004
Rui Liu, Ping Zhao, Juan Tan, Yue Peng, Yiping Zheng
Objective: To evaluate the clinical significance of self-monitoring 24-hour intraocular pressure (IOP) in primary open angle glaucoma (POAG) patients with medical treatment. Methods: This was a case series study. Forty-two POAG patients who had acceptable clinic IOP reading controlled by medicine were selected in shenyang Aier Eye Hospital from August 2017 to January 2019, and divided into group A (IOP: 12.86±1.40 mmHg) and group B (IOP: 17.82±1.40 mmHg) based on the baseline IOP. All participants were trained to use the iCare HOME rebound tonometer to measure 24-hour IOP at home by themselves after certification. 24-hour IOP values was obtained every 2 hour starting from 7:30. The IOP was measured immediately in sitting position after waking up during 23:30 to 5:30. The observation indices included mean IOP, peak IOP and IOP fluctuation amplitude in different periods. The timing of peak IOP and the proportion of patients changing treatment were counted. One-way ANOVA, Kruskal-Wallis H test, t-tests and χ2 test were used to analyze the data. Results: There was no significant difference among the mean IOP measured in the period of clinic, office hours and 24-hour (F=1.314, P=0.271). The peak IOP during 24-hour was higher than that during office hours and that during the clinic period (H=-40.979, -51.363, all P<0.001). 83.6% of the patients' peak IOP occurred outside the office hours (86.5% in group A and 80.6% in group B), especially in the night, with a proportion as high as 67.1% (64.9% in group A and 69.4% in group B). The 24-hour IOP fluctuation of all patients, as well as the patients in group A and group B, were higher than that during office hours (t=11.166, 8.110, 7.929, all P<0.001). 63.0% patients' 24-hour IOP fluctuation was greater than or equal to 8 mmHg (51.4% in group A, 75.0% in group B). 49.3% patients' clinical management was changed based on the result of self-monitoring 24-hour IOP, and the changing proportion in group B (63.9%) was higher than that in group A (35.1%) (χ2=6.035, P=0.014). Conclusions: Self-measurement of 24-hour IOP in POAG patients with medical treatment would identify IOP peaks and fluctuations missed in routine clinical practice, which can be used as an important evidence for clinician to evaluate therapeutic effects and adjust clinical management. Key words: primary open angle glaucoma; tonometer; 24-hour intraocular pressure
{"title":"Clinical Effect of Self-Monitoring 24-Hour Intraocular Pressure in Medical Treated Glaucoma Patients","authors":"Rui Liu, Ping Zhao, Juan Tan, Yue Peng, Yiping Zheng","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.004","url":null,"abstract":"Objective: \u0000To evaluate the clinical significance of self-monitoring 24-hour intraocular pressure (IOP) in primary open angle glaucoma (POAG) patients with medical treatment. \u0000 \u0000 \u0000Methods: \u0000This was a case series study. Forty-two POAG patients who had acceptable clinic IOP reading controlled by medicine were selected in shenyang Aier Eye Hospital from August 2017 to January 2019, and divided into group A (IOP: 12.86±1.40 mmHg) and group B (IOP: 17.82±1.40 mmHg) based on the baseline IOP. All participants were trained to use the iCare HOME rebound tonometer to measure 24-hour IOP at home by themselves after certification. 24-hour IOP values was obtained every 2 hour starting from 7:30. The IOP was measured immediately in sitting position after waking up during 23:30 to 5:30. The observation indices included mean IOP, peak IOP and IOP fluctuation amplitude in different periods. The timing of peak IOP and the proportion of patients changing treatment were counted. One-way ANOVA, Kruskal-Wallis H test, t-tests and χ2 test were used to analyze the data. \u0000 \u0000 \u0000Results: \u0000There was no significant difference among the mean IOP measured in the period of clinic, office hours and 24-hour (F=1.314, P=0.271). The peak IOP during 24-hour was higher than that during office hours and that during the clinic period (H=-40.979, -51.363, all P<0.001). 83.6% of the patients' peak IOP occurred outside the office hours (86.5% in group A and 80.6% in group B), especially in the night, with a proportion as high as 67.1% (64.9% in group A and 69.4% in group B). The 24-hour IOP fluctuation of all patients, as well as the patients in group A and group B, were higher than that during office hours (t=11.166, 8.110, 7.929, all P<0.001). 63.0% patients' 24-hour IOP fluctuation was greater than or equal to 8 mmHg (51.4% in group A, 75.0% in group B). 49.3% patients' clinical management was changed based on the result of self-monitoring 24-hour IOP, and the changing proportion in group B (63.9%) was higher than that in group A (35.1%) (χ2=6.035, P=0.014). \u0000 \u0000 \u0000Conclusions: \u0000Self-measurement of 24-hour IOP in POAG patients with medical treatment would identify IOP peaks and fluctuations missed in routine clinical practice, which can be used as an important evidence for clinician to evaluate therapeutic effects and adjust clinical management. \u0000 \u0000 \u0000Key words: \u0000primary open angle glaucoma; tonometer; 24-hour intraocular pressure","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"6 1","pages":"20-26"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88432837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2020.01.010
Ling Chen, Longbo Wen, Weizhong Lan, Xiaoning Li, Zhikuan Yang
Objective: To establish a correlation model between static refraction and the main refractive parameters of children aged 3-12 years. Methods: This cross sectional study was divided into two parts. In part one, in Changsha Aier Eye Hospital from July 2014 to June 2016, 245 children were randomly selected and measurements were taken of their axial length (AL), corneal curvature (Km) and anterior chamber depth, spherical equivalent refractive (SE) and calculated lens power (LP). The correlations between refraction and the refractive parameters were analyzed to establisha correlative mathematical model. In part two, in Changsha Aier Eye Hospital from July to December 2016, 43 children were randomly selected to measure the above refractive parameters and their cycloplegic refraction (SEmeasured). The lens power and static refraction (SEcalculated) were calculated. The consistency between SEmeasured and SEcalculated was compared by Bland-Altman analysis. Results: The correlation model was established as follows: The correlation coefficients between SE and AL, Km and LP were -0.95, -0.83 and -0.62, respectively (all P<0.001). SE=110.56-2.51×AL-0.97×Km-0.44×LP (R2=0.95, F=2534.52, P<0.001). There was a significant correlation between SEmeasured and SEcalculated (r=0.97, P<0.001), the 95% limit of agreement was -1.00-0.63 D, average error was -0.19 D (95% consistency limit: -0.28 to -0.10 D), and 81.40% of the data points were within the clinically acceptable range (-0.55 to 0.55 D). Conclusions: The axial length is the most important factor in refraction besides corneal curvature and lens power. The refraction correlation model can accurately estimate the static refraction of children from 3 to 12 years old. Key words: refraction; axial length; corneal power; lens power; correlation model
{"title":"Establishment of Main Refractive Parametric Regression Models in Schoolchildren Aged 3 to 12 Years","authors":"Ling Chen, Longbo Wen, Weizhong Lan, Xiaoning Li, Zhikuan Yang","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.010","url":null,"abstract":"Objective: To establish a correlation model between static refraction and the main refractive parameters of children aged 3-12 years. Methods: This cross sectional study was divided into two parts. In part one, in Changsha Aier Eye Hospital from July 2014 to June 2016, 245 children were randomly selected and measurements were taken of their axial length (AL), corneal curvature (Km) and anterior chamber depth, spherical equivalent refractive (SE) and calculated lens power (LP). The correlations between refraction and the refractive parameters were analyzed to establisha correlative mathematical model. In part two, in Changsha Aier Eye Hospital from July to December 2016, 43 children were randomly selected to measure the above refractive parameters and their cycloplegic refraction (SEmeasured). The lens power and static refraction (SEcalculated) were calculated. The consistency between SEmeasured and SEcalculated was compared by Bland-Altman analysis. Results: The correlation model was established as follows: The correlation coefficients between SE and AL, Km and LP were -0.95, -0.83 and -0.62, respectively (all P<0.001). SE=110.56-2.51×AL-0.97×Km-0.44×LP (R2=0.95, F=2534.52, P<0.001). There was a significant correlation between SEmeasured and SEcalculated (r=0.97, P<0.001), the 95% limit of agreement was -1.00-0.63 D, average error was -0.19 D (95% consistency limit: -0.28 to -0.10 D), and 81.40% of the data points were within the clinically acceptable range (-0.55 to 0.55 D). Conclusions: The axial length is the most important factor in refraction besides corneal curvature and lens power. The refraction correlation model can accurately estimate the static refraction of children from 3 to 12 years old. Key words: refraction; axial length; corneal power; lens power; correlation model","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"7 1","pages":"58-63"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90855290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2020.01.005
Yue Peng, Ping Zhao, Juan Tan, Rui Liu, Yiping Zheng
Objective: To evaluate the 24-hour efficacy of tafluprost on the reduction of intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and ocular hypertension (OHT). Methods: In this case-series study, a total of 43 eyes of 22 newly diagnosed patients with POAG and OHT from Shengyang Aier Eye Hospital were enrolled. All patients were trained to use an Icare HOME tonometer to measure IOP by themselves. For the certificated patients, aphysician used GAT to measure their IOP three times, and then the patients used Icare HOME to measure 24-hour IOP by themselves. Patients was given tafluprost once a day at 21∶00. Icare HOME was used by the patients themselves to measure 24-hour IOP again one month later. A one-way ANOVA and Bland-Altman analysis were used to compare the consistency of the GAT used by a physician and the Icare HOME used by patients to measure IOP. A paired t test was used to compare IOP at each time point, the mean, the peak, the valley and the fluctuation of 24-hour IOP before and after treatment with tafluprost. Results: The mean IOPs measured with GAT by a physician and Icare HOME by patients were 18.2±3.7 mmHg (1 mmHg=0.133 kPa) and 17.4±4.2 mmHg, respectively, with no statistically significant difference (F=0.837, P=0.363). Bland-Altman analysis showed that there was a good consistency between GAT measured by a physician and Icare HOME measured by patients. IOP decreased at all time points of assessment after 1 month (all P<0.05). The range of IOP reduction at different time points was 1.8 to 5.5 mmHg (all P<0.05). The mean, the peak, the valley, and the fluctuation of IOP at baseline were 19.4±5.0, 25.0±5.8, 14.1±4.5 and 10.9±3.8 mmHg, respectively, and were reduced to 15.6±4.2, 20.4±4.5, 11.3±3.6 and 9.2±2.9 mmHg after treatment (t=9.450, 9.636, 5.939, 3.137, all P<0.05). Conclusions: Tafluprost provides effective 24-hour IOP reduction in newly diagnosed patients with POAG and OHT. Key words: glaucoma, open-angle; ocular hypertension; tonometry, ocular; tafluprost
{"title":"Effect of Tafluprost on 24-Hour Intraocular Pressure in Patients with Primary Open Angle Glaucoma and Ocular Hypertension","authors":"Yue Peng, Ping Zhao, Juan Tan, Rui Liu, Yiping Zheng","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.005","url":null,"abstract":"Objective: \u0000To evaluate the 24-hour efficacy of tafluprost on the reduction of intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) and ocular hypertension (OHT). \u0000 \u0000 \u0000Methods: \u0000In this case-series study, a total of 43 eyes of 22 newly diagnosed patients with POAG and OHT from Shengyang Aier Eye Hospital were enrolled. All patients were trained to use an Icare HOME tonometer to measure IOP by themselves. For the certificated patients, aphysician used GAT to measure their IOP three times, and then the patients used Icare HOME to measure 24-hour IOP by themselves. Patients was given tafluprost once a day at 21∶00. Icare HOME was used by the patients themselves to measure 24-hour IOP again one month later. A one-way ANOVA and Bland-Altman analysis were used to compare the consistency of the GAT used by a physician and the Icare HOME used by patients to measure IOP. A paired t test was used to compare IOP at each time point, the mean, the peak, the valley and the fluctuation of 24-hour IOP before and after treatment with tafluprost. \u0000 \u0000 \u0000Results: \u0000The mean IOPs measured with GAT by a physician and Icare HOME by patients were 18.2±3.7 mmHg (1 mmHg=0.133 kPa) and 17.4±4.2 mmHg, respectively, with no statistically significant difference (F=0.837, P=0.363). Bland-Altman analysis showed that there was a good consistency between GAT measured by a physician and Icare HOME measured by patients. IOP decreased at all time points of assessment after 1 month (all P<0.05). The range of IOP reduction at different time points was 1.8 to 5.5 mmHg (all P<0.05). The mean, the peak, the valley, and the fluctuation of IOP at baseline were 19.4±5.0, 25.0±5.8, 14.1±4.5 and 10.9±3.8 mmHg, respectively, and were reduced to 15.6±4.2, 20.4±4.5, 11.3±3.6 and 9.2±2.9 mmHg after treatment (t=9.450, 9.636, 5.939, 3.137, all P<0.05). \u0000 \u0000 \u0000Conclusions: \u0000Tafluprost provides effective 24-hour IOP reduction in newly diagnosed patients with POAG and OHT. \u0000 \u0000 \u0000Key words: \u0000glaucoma, open-angle; ocular hypertension; tonometry, ocular; tafluprost","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"10 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82358463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2020.01.007
Yifan Liu
Objective: To study the effects of light/dark adaptation times on flash electroretinograms in normal adult cynomolgus monkeys. Methods: In this experimental study, three adult cynomolgus monkeys were selected and stimulated with standard electroretinogram (ERG) parameters after dark adaptation for 20 min, 40 min and 60 min. The scotopic-ERG was recorded using aroutine procedure. After dark adaptation for 40 min, the photopic-ERG was recorded for 1 min, 5 min and 10 min. One-way ANOVA was used to compare the amplitude and latency. Results: There was no significant difference in the latencies of a and b waves and OPs in the scotopic-ERG (F=0.052, P=0.949). When the dark-adaption time was less than 40 min, the amplitudes of the a and b waves and OPs increased significantly as the adaptation time increased (F=50.800, P<0.001). When the dark-adaptation time was more than 40 min, the amplitude reached the maximum and no longer increased with time (F=0.016, P=0.899). For the photopic-ERG, the implicit times of the a and b waves were also unaffected by the length of the light-adaptation time (F=0.980, P=0.381). The amplitudes of the a and b waves reached their maximum after 5 minutes of light adaptation (F=4.789, P=0.036) and tended to be stable over time (F=0.135, P=0.717). Conclusions: In a certain period of time, the results of flash ERG of cynomolgus monkeys are greatly affected by bright/dark time. So, the dark-adaptation time for scotopic-ERG recording in cynomolgus monkeys should be at least 40 minutes, and the photopic-ERG are best recorded after 5 minutes of light adaption. Key words: light-adaptation; dark-adaptation; electroretinogram; cynomolgus monkey
{"title":"Changes in the Electroretinogram in Normal Cynomolgus Monkeys at Different Adaptation Times","authors":"Yifan Liu","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.007","url":null,"abstract":"Objective: \u0000To study the effects of light/dark adaptation times on flash electroretinograms in normal adult cynomolgus monkeys. \u0000 \u0000 \u0000Methods: \u0000In this experimental study, three adult cynomolgus monkeys were selected and stimulated with standard electroretinogram (ERG) parameters after dark adaptation for 20 min, 40 min and 60 min. The scotopic-ERG was recorded using aroutine procedure. After dark adaptation for 40 min, the photopic-ERG was recorded for 1 min, 5 min and 10 min. One-way ANOVA was used to compare the amplitude and latency. \u0000 \u0000 \u0000Results: \u0000There was no significant difference in the latencies of a and b waves and OPs in the scotopic-ERG (F=0.052, P=0.949). When the dark-adaption time was less than 40 min, the amplitudes of the a and b waves and OPs increased significantly as the adaptation time increased (F=50.800, P<0.001). When the dark-adaptation time was more than 40 min, the amplitude reached the maximum and no longer increased with time (F=0.016, P=0.899). For the photopic-ERG, the implicit times of the a and b waves were also unaffected by the length of the light-adaptation time (F=0.980, P=0.381). The amplitudes of the a and b waves reached their maximum after 5 minutes of light adaptation (F=4.789, P=0.036) and tended to be stable over time (F=0.135, P=0.717). \u0000 \u0000 \u0000Conclusions: \u0000In a certain period of time, the results of flash ERG of cynomolgus monkeys are greatly affected by bright/dark time. So, the dark-adaptation time for scotopic-ERG recording in cynomolgus monkeys should be at least 40 minutes, and the photopic-ERG are best recorded after 5 minutes of light adaption. \u0000 \u0000 \u0000Key words: \u0000light-adaptation; dark-adaptation; electroretinogram; cynomolgus monkey","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"10 1","pages":"39-43"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78644680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2020.01.001
C. Ye, Xiaoyan Wang, J. Meng, Yuan Lan, Haixia Wu, Min Li, F. Lu, Y. Liang
Objective: To evaluate and compare the methodological quality of the glaucoma clinical practice guidelines (CPGs) and to provide references and recommendations for glaucoma guidelines. Methods: The Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument was used to assess the seven guidelines, including the AAO's Preferred Practice Pattern (PPP) in Primary Angle Closure (AAO-PAC), the AAO's PPP in Primary Open-Angle Glaucoma (AAO-POAG), the AAO's PPP in Primary Open-Angle Glaucoma Suspect (AAO-POAGS), the EGS's Terminology and Guidelines for Glaucoma (EGS), ICO Guidelines for Glaucoma Eye Care (ICO), and Asia Pacific Glaucoma Guidelines (APGG) and Consensus of Glaucoma: China (CG). Domain scores were compared and intraclass correlation coefficients (ICCs) and 95% confidence intervals (CI) were calculated. Results: The ICCs of the seven guidelines were above 0.9. In general, all the appraised guidelines scored favorably in domain 1 (Scope and Purpose) and domain 4 (Clarity of Presentation), whereas the other domains scored less favorably. The average scores of six domains involved in the included guidelines were 84%±19% (domain 1, Scope and Purpose), 37%±18% (domain 2, Stakeholder Involvement), 25%±25% (domain 3, Rigor of Development), 90%±16% (domain 4, Clarity of Presentation), 34%±10% (domain 5, Application), 40%±34% (domain 6, Editorial). The six domains' respective scores for AAO-POAGS were 99%, 42%, 61%, 97%, 41%, 77%, and for Consensus of Glaucoma: China were 47%, 4%, 8%, 57%, 17%, 0%. Conclusions: AAO-POAGS were strongly recommended among the seven guidelines. There was much room for Chinese glaucoma guidelines to improve in formulating more rigorous guidelines. Key words: practice guideline; quality evaluation; Appraisal of Guidelines for Research and Evaluation II; glaucoma
{"title":"Assessment of the Methodological Quality of Glaucoma Clinical Practice Guidelines Using the AGREE II Instrument","authors":"C. Ye, Xiaoyan Wang, J. Meng, Yuan Lan, Haixia Wu, Min Li, F. Lu, Y. Liang","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.001","url":null,"abstract":"Objective: \u0000To evaluate and compare the methodological quality of the glaucoma clinical practice guidelines (CPGs) and to provide references and recommendations for glaucoma guidelines. \u0000 \u0000 \u0000Methods: \u0000The Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument was used to assess the seven guidelines, including the AAO's Preferred Practice Pattern (PPP) in Primary Angle Closure (AAO-PAC), the AAO's PPP in Primary Open-Angle Glaucoma (AAO-POAG), the AAO's PPP in Primary Open-Angle Glaucoma Suspect (AAO-POAGS), the EGS's Terminology and Guidelines for Glaucoma (EGS), ICO Guidelines for Glaucoma Eye Care (ICO), and Asia Pacific Glaucoma Guidelines (APGG) and Consensus of Glaucoma: China (CG). Domain scores were compared and intraclass correlation coefficients (ICCs) and 95% confidence intervals (CI) were calculated. \u0000 \u0000 \u0000Results: \u0000The ICCs of the seven guidelines were above 0.9. In general, all the appraised guidelines scored favorably in domain 1 (Scope and Purpose) and domain 4 (Clarity of Presentation), whereas the other domains scored less favorably. The average scores of six domains involved in the included guidelines were 84%±19% (domain 1, Scope and Purpose), 37%±18% (domain 2, Stakeholder Involvement), 25%±25% (domain 3, Rigor of Development), 90%±16% (domain 4, Clarity of Presentation), 34%±10% (domain 5, Application), 40%±34% (domain 6, Editorial). The six domains' respective scores for AAO-POAGS were 99%, 42%, 61%, 97%, 41%, 77%, and for Consensus of Glaucoma: China were 47%, 4%, 8%, 57%, 17%, 0%. \u0000 \u0000 \u0000Conclusions: \u0000AAO-POAGS were strongly recommended among the seven guidelines. There was much room for Chinese glaucoma guidelines to improve in formulating more rigorous guidelines. \u0000 \u0000 \u0000Key words: \u0000practice guideline; quality evaluation; Appraisal of Guidelines for Research and Evaluation II; glaucoma","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"63 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88569794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.12.003
You Yuan, Panpan Li, Mengyu Wang, Xiaobo Huang, Yu Song, E. Song
Objective: To compare the correlations and differences between autorefraction measured by OPD-Scan III in light and dark modes with non-cycloplegic subjective refraction. Methods: This was a series of case studies. One hundred and two patients (204 eyes) with refractive errors were selected from the Ideal Ophthalmology Hospital affiliated to Soochow University during July 2018. All patients underwent autorefraction with OPD-Scan III and subjective refraction with a competent optometrist. Statistical analyses and comparisons were made on spherical (S), cylinder (C), spherical equivalent (SE), J0 (Jackson cross-cylindervalues at 180° and 90°) and J45 (Jackson cross-cylindervalues at 135° and 45°). Data were statistically analyzed using a t test, regression test and Pearson correlation. Results: The values of S, C, SE, J0 and J45 measured under OPD-Scan III light mode were positively correlated with those measured by subjective optometry (r=0.797, 0.877, 0.806, 0.918, 0.623, all P<0.001). All the measurements showed statistically significant differences. The values of S, C and SE measured under OPD-Scan III illumination were -0.33 D, -0.08 D, and -0.37 D were higher than those measured under subjective optometry, and the differences were statistically significant between the two measurements (t=4.232, 3.058, 4.741, all P<0.05). There was no statistically significant difference for J0 but J45 showed a statistically significant difference (t=-2.342, P=0.021). The values of S, C, SE, J0, and J45 measured under OPD-Scan III dark light mode were positively correlated with the values measured by subjective optometry (r=0.877, 0.629, 0.894, 0.753, 0.466, all P<0.001). The values of S, C and SE measured by OPD-Scan III under dark light were higher than those measured by subjective optometry, -0.57 D, -0.41 D, and -0.77 D, respectively, and the differences were statistically significant between the two measurements (t=8.864, 8.777, 3.263, all P<0.001). There was no statistically significant difference for J0 and J45. Conclusions: The correlations and differences between the autorefractions measured by OPD-Scan III in light and dark mode with subjective refraction showed statistical significance. But the difference between autorefraction measured by OPD-Scan III in light mode and subjective optometry is small, which is acceptable in the clinic. Key words: OPD-Scan III; refractive errors; autorefraction; subjective refraction
{"title":"Comparison of the Correlations and Differences between the Autorefraction Measured by OPD-Scan III and Non-Cycloplegic Subjective Refraction","authors":"You Yuan, Panpan Li, Mengyu Wang, Xiaobo Huang, Yu Song, E. Song","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.12.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.12.003","url":null,"abstract":"Objective: \u0000To compare the correlations and differences between autorefraction measured by OPD-Scan III in light and dark modes with non-cycloplegic subjective refraction. \u0000 \u0000 \u0000Methods: \u0000This was a series of case studies. One hundred and two patients (204 eyes) with refractive errors were selected from the Ideal Ophthalmology Hospital affiliated to Soochow University during July 2018. All patients underwent autorefraction with OPD-Scan III and subjective refraction with a competent optometrist. Statistical analyses and comparisons were made on spherical (S), cylinder (C), spherical equivalent (SE), J0 (Jackson cross-cylindervalues at 180° and 90°) and J45 (Jackson cross-cylindervalues at 135° and 45°). Data were statistically analyzed using a t test, regression test and Pearson correlation. \u0000 \u0000 \u0000Results: \u0000The values of S, C, SE, J0 and J45 measured under OPD-Scan III light mode were positively correlated with those measured by subjective optometry (r=0.797, 0.877, 0.806, 0.918, 0.623, all P<0.001). All the measurements showed statistically significant differences. The values of S, C and SE measured under OPD-Scan III illumination were -0.33 D, -0.08 D, and -0.37 D were higher than those measured under subjective optometry, and the differences were statistically significant between the two measurements (t=4.232, 3.058, 4.741, all P<0.05). There was no statistically significant difference for J0 but J45 showed a statistically significant difference (t=-2.342, P=0.021). The values of S, C, SE, J0, and J45 measured under OPD-Scan III dark light mode were positively correlated with the values measured by subjective optometry (r=0.877, 0.629, 0.894, 0.753, 0.466, all P<0.001). The values of S, C and SE measured by OPD-Scan III under dark light were higher than those measured by subjective optometry, -0.57 D, -0.41 D, and -0.77 D, respectively, and the differences were statistically significant between the two measurements (t=8.864, 8.777, 3.263, all P<0.001). There was no statistically significant difference for J0 and J45. \u0000 \u0000 \u0000Conclusions: \u0000The correlations and differences between the autorefractions measured by OPD-Scan III in light and dark mode with subjective refraction showed statistical significance. But the difference between autorefraction measured by OPD-Scan III in light mode and subjective optometry is small, which is acceptable in the clinic. \u0000 \u0000 \u0000Key words: \u0000OPD-Scan III; refractive errors; autorefraction; subjective refraction","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"84 1","pages":"895-899"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74934931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.12.002
Zhenghua Lin, Zhao Chen, Wenyu Gao, Can Chen, Weizhong Lan, Zhikuan Yang
Objective: This study aimed to evaluate the accuracy and efficiency of the Visual Adaptive Optics Simulator (VAO, Spain) which is able to measure objective and subjective refraction. Methods: The refractor VAO was an instrument based on the principle of adaptive optics. This was a series case study that included patients in Changsha Aier Eye Hospital from October to November 2017. Subjects with myopia were first measured by experienced optometrists for objective and subjective refraction using an autorefractor (Nidek ARK-1) and phoropter, respectively (designated as the "traditional approach"). Then, these subjects were again measured by a fresh technician with the VAO-based approach. The agreement of the results by these two approaches was compared with an intraclass correlation coefficient (ICC) and a paired-t test analysis. The efficiency of the VAO-based approach was also compared to the traditional approach with a paired-t test. Results: Seventy subjects (140 eyes, 38 males) with a mean age of 13.2±2.2 years participated in the study. The ICC of the objective refraction between the two approaches was 0.897, 0.907, 0.732 for spherical power, J0 and J45, respectively. The ICC of subjective refraction between the two approaches was 0.937, 0.891, 0.543, respectively. Specifically, the mean difference in objective and subjective refraction for spherical power with the two approaches was 0.46 D (95%CI: 0.36, 0.55 D) (t=9.663, P<0.001), and 0.32 D (95%CI: 0.25, 0.39 D) (t=9.087, P<0.001). However, the difference was found to diminish with an increase in the degree of myopia (r=-0.261, P<0.001) and the difference inspherical power dropped by 0.22 D [0.14 D, 0.32 D] for moderate-high myopia (spherical power <-3.00 D; t=4.987, P<0.001). For cylindrical power, there was no significant difference between the two approaches. Never the less, the average measurement time for the VAO-based approach was found to be significantly shorter than the traditional approach (5.9±1.9 min vs. 7.2±0.7 min, t=6.100, P<0.001). Conclusions: VAO produces clinically similar results compared to the traditional approach and the difference between the two approaches tends to be reduced with a greater degree of myopia. In addition, the efficiency of VAO is significantly better than the traditional approach. Key words: adaptive optics; myopia; refraction
目的:评价能够测量客观和主观折射的视觉自适应光学模拟器(VAO，西班牙)的精度和效率。方法:折射式VAO是一种基于自适应光学原理的仪器。这是一个系列案例研究，包括2017年10月至11月在长沙爱尔眼科医院就诊的患者。近视患者首先由经验丰富的验光师分别使用自动折射镜(Nidek ARK-1)和屈光镜(称为“传统方法”)测量客观和主观屈光。然后，这些受试者再次由一名新技术人员使用基于vao的方法进行测量。用类内相关系数(ICC)和配对t检验分析比较两种方法的一致性。通过配对t检验，还比较了基于var的方法与传统方法的效率。结果:共纳入受试者70例(140只眼，男性38例)，平均年龄13.2±2.2岁。两种方法的物镜折射ICC分别为0.897,0.907,J0和J45。两种方法的主观折射ICC分别为0.937、0.891、0.543。具体而言，两种方法的客观折射和主观折射的平均差为0.46 D (95%CI: 0.36, 0.55 D) (t=9.663, P<0.001)和0.32 D (95%CI: 0.25, 0.39 D) (t=9.087, P<0.001)。然而，随着近视程度的增加，这种差异逐渐减小(r=-0.261, P<0.001)，中高度近视(球面度数<-3.00 D;t = 4.987, P < 0.001)。对于圆柱形功率，两种方法之间无显著差异。尽管如此，基于vao的方法的平均测量时间明显短于传统方法(5.9±1.9 min vs. 7.2±0.7 min, t=6.100, P<0.001)。结论:VAO与传统入路的临床效果相似，且随近视程度的增加，两者之间的差异有缩小的趋势。此外，VAO的效率也明显优于传统方法。关键词:自适应光学;近视;折射
{"title":"Accuracy and Efficiency of Refraction for Myopes Based on the Visual Adaptive Optics Simulator","authors":"Zhenghua Lin, Zhao Chen, Wenyu Gao, Can Chen, Weizhong Lan, Zhikuan Yang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.12.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.12.002","url":null,"abstract":"Objective: \u0000This study aimed to evaluate the accuracy and efficiency of the Visual Adaptive Optics Simulator (VAO, Spain) which is able to measure objective and subjective refraction. \u0000 \u0000 \u0000Methods: \u0000The refractor VAO was an instrument based on the principle of adaptive optics. This was a series case study that included patients in Changsha Aier Eye Hospital from October to November 2017. Subjects with myopia were first measured by experienced optometrists for objective and subjective refraction using an autorefractor (Nidek ARK-1) and phoropter, respectively (designated as the \"traditional approach\"). Then, these subjects were again measured by a fresh technician with the VAO-based approach. The agreement of the results by these two approaches was compared with an intraclass correlation coefficient (ICC) and a paired-t test analysis. The efficiency of the VAO-based approach was also compared to the traditional approach with a paired-t test. \u0000 \u0000 \u0000Results: \u0000Seventy subjects (140 eyes, 38 males) with a mean age of 13.2±2.2 years participated in the study. The ICC of the objective refraction between the two approaches was 0.897, 0.907, 0.732 for spherical power, J0 and J45, respectively. The ICC of subjective refraction between the two approaches was 0.937, 0.891, 0.543, respectively. Specifically, the mean difference in objective and subjective refraction for spherical power with the two approaches was 0.46 D (95%CI: 0.36, 0.55 D) (t=9.663, P<0.001), and 0.32 D (95%CI: 0.25, 0.39 D) (t=9.087, P<0.001). However, the difference was found to diminish with an increase in the degree of myopia (r=-0.261, P<0.001) and the difference inspherical power dropped by 0.22 D [0.14 D, 0.32 D] for moderate-high myopia (spherical power <-3.00 D; t=4.987, P<0.001). For cylindrical power, there was no significant difference between the two approaches. Never the less, the average measurement time for the VAO-based approach was found to be significantly shorter than the traditional approach (5.9±1.9 min vs. 7.2±0.7 min, t=6.100, P<0.001). \u0000 \u0000 \u0000Conclusions: \u0000VAO produces clinically similar results compared to the traditional approach and the difference between the two approaches tends to be reduced with a greater degree of myopia. In addition, the efficiency of VAO is significantly better than the traditional approach. \u0000 \u0000 \u0000Key words: \u0000adaptive optics; myopia; refraction","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"9 1","pages":"888-894"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90224767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.12.008
Jue Liu, Jing Zhang, Ying-ying Xu
Objective: To study the relationship between macular pigment optical density, macular thickness and myopia in adults. Methods: One hundred nineteen subjects were divided into two groups according to age: 20 to 33 years and 34 to 45 years. Subjects were then divided into anemmetropia group and amyopia group according to spherical equivalence (SE). The latter were divided into a low myopia group, moderate myopia group and high myopia group. The mean macular pigment optical density (Mean OD) and maximum macular pigment optical density (Max OD) were measured with spectral fundus reflectometry. Central retinal thickness (CRT) and paracentral retinal thickness were measured with optical coherence tomography (OCT). The data were analyzed by a paired t-test and single factor variance. Results: Comparison of Mean OD values and Max OD values between the emmetropia group and myopia groups for the ages 20 to 33 and 34 to 45 showed statistically significant differences (P<0.001). When the emmetropia group and the myopia group were compared to each other as two groups, the differences were statistically significant (P<0.001). When the emmetropia group and the myopia group were compared to each other, the differences were statistically significant (P<0.001). Conclusions: This study shows macular pigment optical density, macular thickness in high myopia is significant different with low to moderate myopia. Key words: macular pigment optical density; central retinal thickness; myopia
{"title":"Relationship between Macular Pigment Optical Density, Macular Thickness and Myopia in Adults","authors":"Jue Liu, Jing Zhang, Ying-ying Xu","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.12.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.12.008","url":null,"abstract":"Objective: \u0000To study the relationship between macular pigment optical density, macular thickness and myopia in adults. \u0000 \u0000 \u0000Methods: \u0000One hundred nineteen subjects were divided into two groups according to age: 20 to 33 years and 34 to 45 years. Subjects were then divided into anemmetropia group and amyopia group according to spherical equivalence (SE). The latter were divided into a low myopia group, moderate myopia group and high myopia group. The mean macular pigment optical density (Mean OD) and maximum macular pigment optical density (Max OD) were measured with spectral fundus reflectometry. Central retinal thickness (CRT) and paracentral retinal thickness were measured with optical coherence tomography (OCT). The data were analyzed by a paired t-test and single factor variance. \u0000 \u0000 \u0000Results: \u0000Comparison of Mean OD values and Max OD values between the emmetropia group and myopia groups for the ages 20 to 33 and 34 to 45 showed statistically significant differences (P<0.001). When the emmetropia group and the myopia group were compared to each other as two groups, the differences were statistically significant (P<0.001). When the emmetropia group and the myopia group were compared to each other, the differences were statistically significant (P<0.001). \u0000 \u0000 \u0000Conclusions: \u0000This study shows macular pigment optical density, macular thickness in high myopia is significant different with low to moderate myopia. \u0000 \u0000 \u0000Key words: \u0000macular pigment optical density; central retinal thickness; myopia","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"62 1","pages":"924-929"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74116819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.12.009
Guo Fengfang, F. Xuejun
Objective: To compare the changes in dry eye parameters and corneal sensation between FS-LASIK (femtosecond laser-assisted in situ keratomileusis) and SMILE (small incision lenticule extraction), and to investigate the effect of the type of surgery on tear film and corneal sensation; to analyze the correlation between the two indicators. Methods: In this prospective non-randomized control study, 48 eyes of 24 patients underwent FS-LASIK and 41 eyes of 21 patients underwent SMILE. The tear meniscus height (TMH) and non-invasive tear film break-up time, including NIF-BUT and NIAvg-BUT, were measured by a Keratograph 5M ocular surface analyzer and were evaluated preoperatively and at 1 and 3 months postoperatively. Central corneal sensation was examined as well. Repeated measures ANOVA was used for preoperative and postoperative comparison within the same group; an independent sample t test was used for comparison of general data and dry eye parameters between the different groups; Spearman correlation analysis was used for the correlation between central corneal sensation and dry eye parameters. Results: The values of all dry eye parameters and central corneal sensation showed no differences before surgery between the two groups. In the FS-LASIK and SMILE groups, the TMH results decreased at both postoperative time points (F=21.213, P<0.001; F=14.648, P<0.001). The TMH results were higher in the SMILE group than that in the FS-LASIK group at both postoperative time points (t=-5.549, P<0.001; t=-3.028, P=0.003). In the FS-LASIK group, the NIF-BUT values decreased within 1 month after surgery (F=4.603, P=0.019). In the SMILE group, the NIF-BUT values presented no significant decrease at both postoperative time points (F=0.599, P=0.516). The NIF-BUT values were higher in the SMILE group than in the FS-LASIK group at 1 month postoperatively (t=-3.430, P=0.001). The NIAvg-BUT values in the FS-LASIK group decreased within 1 month after surgery (F=3.580, P=0.042). The NIAvg-BUT values presented no significant decrease at both postoperative time points in the SMILE group (F=0.274, P=0.761). The NIAvg-BUT values were higher at both postoperative time points in the SMILE group than in the FS-LASIK group (t=-2.395, P=0.019; t=-2.431, P=0.017). The central corneal sensation results had decreased at both postoperative time points in the FS-LASIK group (F=121.919, P<0.001), but had decreased at only 1 month after surgery in the SMILE group (F=54.032, P<0.001). The central corneal sensation results were better in the SMILE group than in the FS-LASIK group at both postoperative time points (t=-5.367, P<0.001; t=-3.242, P=0.002). There was a positive correlation between central corneal sensation and dry eye parameters at both follow-up time points in both groups (P<0.05). Conclusions: There are different degrees of change in dry eye parameters and central corneal sensation at the early postoperative period in the FS-LASIK and SMILE groups. The dr
目的:比较FS-LASIK(飞秒激光辅助原位角膜磨除术)和SMILE(小切口晶状体摘除术)术后干眼参数和角膜感觉的变化，探讨手术方式对泪膜和角膜感觉的影响;分析两个指标之间的相关性。方法:在前瞻性非随机对照研究中，24例患者48眼行FS-LASIK, 21例患者41眼行SMILE。术前、术后1个月、3个月采用角膜镜5M眼表分析仪测定撕裂半月板高度(TMH)和非侵入性撕裂膜破裂时间(NIF-BUT和NIAvg-BUT)。同时检查角膜中央感觉。同一组内术前、术后比较采用重复测量方差分析;各组间一般资料及干眼参数比较采用独立样本t检验;采用Spearman相关分析角膜中央感觉与干眼参数的相关性。结果:两组患者术前各项干眼指标及角膜中央感觉均无差异。FS-LASIK组和SMILE组TMH在术后两个时间点均下降(F=21.213, P<0.001;F = 14.648, P < 0.001)。术后两个时间点，SMILE组TMH均高于FS-LASIK组(t=-5.549, P<0.001;t = -3.028, P = 0.003)。FS-LASIK组NIF-BUT值在术后1个月内下降(F=4.603, P=0.019)。SMILE组术后两个时间点NIF-BUT值均无明显下降(F=0.599, P=0.516)。术后1个月SMILE组NIF-BUT值高于FS-LASIK组(t=-3.430, P=0.001)。FS-LASIK组NIAvg-BUT值在术后1个月内下降(F=3.580, P=0.042)。SMILE组NIAvg-BUT在术后两个时间点均无明显下降(F=0.274, P=0.761)。SMILE组术后两个时间点NIAvg-BUT值均高于FS-LASIK组(t=-2.395, P=0.019;t = -2.431, P = 0.017)。FS-LASIK组术后两个时间点角膜中央感觉均下降(F=121.919, P<0.001)， SMILE组术后仅1个月角膜中央感觉下降(F=54.032, P<0.001)。术后两个时间点，SMILE组角膜中央感觉均优于FS-LASIK组(t=-5.367, P<0.001;t = -3.242, P = 0.002)。两组患者角膜中央感觉与干眼指标在随访时间点均呈正相关(P<0.05)。结论:FS-LASIK组和SMILE组术后早期干眼参数和角膜中央感觉均有不同程度的改变。SMILE组的干眼参数和角膜中央感觉优于FS-LASIK组。两组患者角膜中央感觉与干眼参数呈正相关。关键词:飞秒辅助激光原位角膜磨镶术;小切口晶状体摘除;干眼参数;角膜的感觉;5M眼表分析仪
{"title":"Comparison of Dry Eye Parameters and Corneal Sensation after FS-LASIK and SMILE Surgery","authors":"Guo Fengfang, F. Xuejun","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.12.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.12.009","url":null,"abstract":"Objective: \u0000To compare the changes in dry eye parameters and corneal sensation between FS-LASIK (femtosecond laser-assisted in situ keratomileusis) and SMILE (small incision lenticule extraction), and to investigate the effect of the type of surgery on tear film and corneal sensation; to analyze the correlation between the two indicators. \u0000 \u0000 \u0000Methods: \u0000In this prospective non-randomized control study, 48 eyes of 24 patients underwent FS-LASIK and 41 eyes of 21 patients underwent SMILE. The tear meniscus height (TMH) and non-invasive tear film break-up time, including NIF-BUT and NIAvg-BUT, were measured by a Keratograph 5M ocular surface analyzer and were evaluated preoperatively and at 1 and 3 months postoperatively. Central corneal sensation was examined as well. Repeated measures ANOVA was used for preoperative and postoperative comparison within the same group; an independent sample t test was used for comparison of general data and dry eye parameters between the different groups; Spearman correlation analysis was used for the correlation between central corneal sensation and dry eye parameters. \u0000 \u0000 \u0000Results: \u0000The values of all dry eye parameters and central corneal sensation showed no differences before surgery between the two groups. In the FS-LASIK and SMILE groups, the TMH results decreased at both postoperative time points (F=21.213, P<0.001; F=14.648, P<0.001). The TMH results were higher in the SMILE group than that in the FS-LASIK group at both postoperative time points (t=-5.549, P<0.001; t=-3.028, P=0.003). In the FS-LASIK group, the NIF-BUT values decreased within 1 month after surgery (F=4.603, P=0.019). In the SMILE group, the NIF-BUT values presented no significant decrease at both postoperative time points (F=0.599, P=0.516). The NIF-BUT values were higher in the SMILE group than in the FS-LASIK group at 1 month postoperatively (t=-3.430, P=0.001). The NIAvg-BUT values in the FS-LASIK group decreased within 1 month after surgery (F=3.580, P=0.042). The NIAvg-BUT values presented no significant decrease at both postoperative time points in the SMILE group (F=0.274, P=0.761). The NIAvg-BUT values were higher at both postoperative time points in the SMILE group than in the FS-LASIK group (t=-2.395, P=0.019; t=-2.431, P=0.017). The central corneal sensation results had decreased at both postoperative time points in the FS-LASIK group (F=121.919, P<0.001), but had decreased at only 1 month after surgery in the SMILE group (F=54.032, P<0.001). The central corneal sensation results were better in the SMILE group than in the FS-LASIK group at both postoperative time points (t=-5.367, P<0.001; t=-3.242, P=0.002). There was a positive correlation between central corneal sensation and dry eye parameters at both follow-up time points in both groups (P<0.05). \u0000 \u0000 \u0000Conclusions: \u0000There are different degrees of change in dry eye parameters and central corneal sensation at the early postoperative period in the FS-LASIK and SMILE groups. The dr","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"1 1","pages":"930-936"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83103046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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