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INVESTIGATION ON A DIARRHEA IN YOUNG CHICKS IN JAPAN 日本一种雏鸡腹泻的调查
Pub Date : 1922-06-25 DOI: 10.1292/JVMS1922.1.93
N. Nakamura
Although it was not known precisely when the diarrhea in young chicks and known as "Babatare" first occurred in our country, especially in the middle part of Honshu, its presence has been recognized for many years. It is said that the first -severe outbreak of this disease was observed by poulterers in Aichi Prefecture in 1907, since which time it has spread widely -i n various prefectures. No attempt was made, however, to determine the exact cause of this disease until 1919, when the first investigation was undertaken by me. Since the beginning of 1919 we have had occasion to examine a number of chicks but lately hatched, sent to us from various parts, all of which were found to have had severe diarrhea before death. Symptoms. -The symptoms exhibited were of a more or less different character according to the stage of infection. In one case, in which the first signs of intestinal trouble were recognized in 24 to 36 hours after hatching, the birds were found at first to have a yellowish white diarrhea, subsequently accompanied by frequent paroxysmal tenesmus. After one or two days the appearance of the diarrhea became pituitous, causing the feathers around the opening of the cloaca to be stained and to stick to one another in drying, until a stage of constipation was brought on. Moreover the skin on that part was irritated by the sticking feathers till inflammation set in. Two or three days later, the chicks were very much worse and fell into convulsions indicating the approach of death. In other cases in which the signs of diarrhea were discovered in from four to seven days after hatching, a complete loss of appetite ensued due to their separa_'tion from the flock and to their attitude in squatting, and the chicks developed severe diarrhea with the aspect mentioned in the previous case and appeared extremely dull. Death occurred
虽然目前还不清楚这种被称为“Babatare”的雏鸡腹泻最早在我国,特别是在本州中部地区发生的确切时间,但它的存在已经得到了多年的承认。据说,1907年爱知县的家禽养殖者观察到该病的第一次严重暴发,此后该病在各县广泛传播。然而,直到1919年,当我进行第一次调查时,才试图确定这种疾病的确切原因。自1919年初以来,我们有机会检查了一些最近孵化的小鸡,这些小鸡是从各地寄给我们的,所有这些小鸡都在死前患有严重的腹泻。症状。根据感染阶段的不同,所表现出的症状或多或少具有不同的特征。在一个案例中,在孵化后的24到36小时内发现了肠道疾病的最初迹象,这些鸟最初被发现有黄白色的腹泻,随后伴随着频繁的阵发性下急。一两天后,腹泻的症状变得严重起来,导致泄殖腔开口周围的羽毛被玷污,并在干燥时相互粘在一起,直到出现便秘的阶段。此外,那部分的皮肤被粘在上面的羽毛刺激到发炎。两三天后,小鸡的情况变得非常糟糕,开始抽搐,表明死亡的临近。在其他情况下,在孵化后4至7天内发现腹泻迹象,由于与鸡群分离和蹲姿,导致食欲完全丧失,雏鸡出现严重腹泻,与上述情况相同,表现非常迟钝。死亡发生
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引用次数: 1
ON THE APPLICATION OF PAPAIN IN THE PREPARATION OF CULTURE-MEDIA 木瓜蛋白酶在培养基制备中的应用研究
Pub Date : 1922-06-25 DOI: 10.1292/JVMS1922.1.81
Saburô Suzuki
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引用次数: 0
COMBINED CARBON DIOXIDE CONTENT OF BLOOD PLASMA IN THE HORSE 马血浆中二氧化碳的综合含量
Pub Date : 1922-06-25 DOI: 10.1292/JVMS1922.1.67
N. Ijichi
Studies in acidosis have recently made a remarkable progress and many valuable reports in connection with it have already been published. The subject is, as is widely known, of great interest both from a physiological and pathological point of view. It would be of no benefit, however, to describe here what acidosis is or what kinds of researches have hitherto been made on the subject. For three years I have devoted myself to the study of this subject with the view of finding out its practical value in veterinary science.As a first step in my experiments, I have measured the CO2 content of horse blood plasma by means of VAN SLYKE'S method which was pulished in 1917 and is now generally recommended as the best method for diagnosing acidosis.The blood used for my experiments was obtained from the jugular vein of the horse, care being taken in doing so not to allow the blood to come in contact with the air. According to the studies of STADI and VAN SLYKE, it is not necessary, for the measurement of the CO2 content, to saturate the venous blood with CO2, at the same tension as in alveolar air, if the blood is drawn from a vein without any stasis. The venous blood employed in my experiments, therefore, is not subjected to any process which was to be carried out for the purpose of saturating the blood with CO2.The results obtained from a number of experiments are as follows:(1) CO2, content of blood-plasma in the normal horse.Experiments in 30 horses (military) show that the CO2, content of blood-plasma varies from 72.1 to 52.8 vol %, that is, 62.6 vol % on the average.It must be noticed here that even in one and the same horse there is a difference between the CO2 content measured in the morning and that obtained in the evening.(2) CO2, content of blood-plasma in the horse under abnormal conditions.(a) Fatigue.In horses which have taken a run of about 390km, the CO2, content has fallen below normal, all of them being in a condition of acidosis; the content of CO2, in 8 tired horses averages 47.0 vol % (53.2-38.1). Comparing the condition of some excessively tired horses with that of horses in a state of slight fatigue, I have found that the CO2, content in blood-plasma, that is, the lowered alkaline reserve, decreases according to the degree of fatigue, so the blood-plasma of the most severely tired horse contains the least volume of CO2.(b) Podophyllitis, colic, influenza pectoralis, and morbus maculosus.In podophyllitis caused by severe exercise, the CO2 content of blood plasma decreases considerably. An examination of the blood-plasma obtained from 7 horses suffering from an attack of podophyllitis showed that the CO2 content averages 54.1 vol %, which means that almost all of them were in a condition of acidosis.It is no unusual matter to find acidosis is proved in a case of severe colic. According to my measurements, the CO2 content of the blood-plasma taken from a horse which has been suffering from colic so severely that he died several hours la
近年来,酸中毒的研究取得了显著进展,并发表了许多有价值的报告。众所周知,从生理学和病理学的角度来看,这一主题都引起了极大的兴趣。然而,在这里描述酸中毒是什么,或者迄今为止在这个问题上进行了什么样的研究,都是无益的。三年来,我一直致力于这一学科的研究,以期发现它在兽医科学中的实用价值。作为我实验的第一步,我用VAN SLYKE的方法测量了马血浆中的二氧化碳含量。VAN SLYKE的方法发表于1917年,现在被普遍推荐为诊断酸中毒的最佳方法。我的实验所用的血液是从马的颈静脉中提取的,我们非常小心,不让血液与空气接触。根据STADI和VAN SLYKE的研究,如果血液是从没有任何停滞的静脉中抽取的,那么测量二氧化碳含量就没有必要使静脉血以与肺泡空气相同的张力饱和。因此,在我的实验中使用的静脉血不受任何过程的影响,而这些过程是为了使血液中充满二氧化碳而进行的。通过多次实验得到的结果如下:(1)正常马血浆中CO2含量。对30匹马(军马)的实验表明,其血浆中CO2的含量在72.1 ~ 52.8%之间,即平均为62.6 vol %。这里必须注意的是,即使是同一匹马,在早上和晚上测量的二氧化碳含量也存在差异。(2)二氧化碳,在异常情况下马的血浆含量。跑了约390公里的马,其二氧化碳含量低于正常水平,均处于酸中毒状态;8匹累马的二氧化碳含量平均为47.0 vol %(53.2-38.1)。我比较了一些过度疲劳的马和轻度疲劳的马的情况,发现血浆中CO2的含量,即降低的碱性储备,随着疲劳程度的增加而减少,所以最严重疲劳的马的血浆中CO2的含量最少。(b)足跖炎、绞痛、胸肌流感、黄斑病变。剧烈运动引起的足跖炎,血浆CO2含量明显降低。对7匹患足跖炎的马的血浆进行的检查显示,二氧化碳含量平均为54.1%,这意味着几乎所有的马都处于酸中毒状态。在严重绞痛的病例中发现酸中毒是很常见的。根据我的测量,从一匹严重绞痛几小时后死亡的马身上提取的血浆中,二氧化碳含量为32.7%。在胸肌流感中,我发现重症时血浆的二氧化碳含量为27.1%,轻度时为50.0%。从患斑斑病的马身上提取的血浆中含有45.7%的CO2。(3)氯气和光气中毒。在一个紧闭的房间里,一匹马暴露在浓度为0.2 vol.‰的氯气中10分钟。取动物血浆CO2含量由67.3%降至49.4%,当血氧浓度达到最大值时,肺水肿症状最为显著。
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引用次数: 1
ON THE IMMUNE SERUM AGAINST FOOTAND-MOUTH DISEASE 口蹄疫免疫血清的研究
Pub Date : 1922-06-25 DOI: 10.1292/JVMS1922.1.101
Susumu Kuragano, T. Mogami
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引用次数: 1
ON THE ANTI-RABIC VACCINATION IN THE DOG 犬抗狂犬病疫苗的研究
Pub Date : 1922-03-31 DOI: 10.1292/JVMS1922.1.47
S. Kondo
1. Of various vaccines which were prepared and tested on animals in the laboratory, the one prepared by incubating the emulsion of the brain and cord from animals infected with fixed virus at 37°C. for 3 days or that prepared by keeping the emulsion at room temperature for 10 days is most applicable for the vaccination in the dog.2. The vaccine prepared by incubating the emulsion at 37°C. is better than that prepared by keeping it at room temeprature, because more uniform attenuation of the virus could be expected in the former treatment.3. As the source of the vaccine the brain and cord of the dog is better than those of rabbit, because the yield in the former is six times more than that in the latter.4. In the dog the vaccine is to be once inoculated subcutaneously in dose of 5c.c.5. The immunity produced by the vaccination lasts for about one year.
1. 在实验室用动物制备和试验的各种疫苗中,一种是用感染了固定病毒的动物的脑和脐带的乳剂在37°C下孵育制备的。3天或室温保存10天制备的乳剂最适用于犬的疫苗接种。乳剂在37℃下孵育制备疫苗。比在室温下处理要好,因为前者可以使病毒的衰减更均匀。作为疫苗的来源,狗的脑和脊髓比兔的好,因为前者的产量是后者的6倍。在狗身上,疫苗应一次皮下接种,剂量为5cc .5。疫苗产生的免疫力持续约一年。
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引用次数: 1
ON THE NATURE OF LUMBAR PARALYSIS IN THE GOAT 论山羊腰麻痹的性质
Pub Date : 1922-03-31 DOI: 10.1292/JVMS1922.1.1
O. Emoto
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引用次数: 0
STUDIES OF THE COMPLEMENT FIXATION REACTION IN RABIES 狂犬病补体固定反应的研究
Pub Date : 1900-01-01 DOI: 10.1292/JVMS1922.8.252
S. Kondo, K. Obana
In 1907, Heller and Tomarkin first reported that the complement fixation reaction gave negative result when tested with the sera of rabbits immunized against rabies fixed virus in the presence of antigens prepared from rabic brains. Friedberger (1907), using the sera of immunized and of rabid animals, was unable to demonstrate any specific fixation. The immune serum gave no more fixation than did the normal serum. Regarding the complement fixation reaction, negative observations were also recorded by Centanni (1908), Donati & Satta (1908), Baroni, Ciuca & JonescuMihaiesti (1908), and recently also by Fei-Fang Tang & Castaneda and by Schultz, Bullock & Brewer (1928). Notwithstanding these negative reports some positive results were obtained by a number of other investigators. Nedrigailoff & Sawtschenko (1911) were able to demonstrate specific fixation with the serum of horse immunized against fixed virus in the presence of antigens of salivary gland from a rabid dog or from a man succumbed to rabies. Zell (1913), testing the serum of street virus-infected animals in the presence of salivary
1907年,Heller和Tomarkin首次报道了在狂犬病脑制备的抗原存在的情况下,用免疫狂犬病固定病毒的兔血清进行补体固定反应的阴性结果。Friedberger(1907)使用免疫动物和患狂犬病动物的血清,无法证明任何特异性固定。免疫血清的固定作用并不比正常血清强。关于补体固定反应,Centanni (1908), Donati & Satta (1908), Baroni, Ciuca & JonescuMihaiesti(1908),以及最近的Fei-Fang Tang & Castaneda和Schultz, Bullock & Brewer(1928)也记录了消极的观察结果。尽管有这些负面报告,但其他一些调查人员也取得了一些积极的结果。Nedrigailoff和Sawtschenko(1911)能够证明,在患有狂犬病的狗或患狂犬病的人的唾液腺抗原存在的情况下,对固定病毒免疫的马血清具有特异性固定。Zell(1913),在唾液存在的情况下测试街头病毒感染动物的血清
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引用次数: 1
Spontaneous Encephalitis of Rabbits 兔自发性脑炎
Pub Date : 1900-01-01 DOI: 10.1292/JVMS1922.16.4_EN71
O. Emoto, S. Kondo, M. Watanabe
We have examined bocteriologically and histo-pathologically the materials of rabbits affected with spontaneous encephalitis, but specific bacteria for this disease have not been found and yet nor gross lessions characteristic for the disease were found macroscopically.We are sure that this spontaneous encephalitis is not caused by bacteria, and it is supposed that this disease may be caused by somh unitary causative agent, because in all cases there are some changes with specific granulom in the brains as histological findings. Judging from the histo-pathological changes, it is supposed that the causative agent has the tendency to be neurotropic.The agent may be the Encephalitozoon cuniculi as Levaditi and his collaborators believed, but we have no positive proof it until this time. Anyhow it is sure that the rabbits inoculated with the brain emulsion of the animals affected with spontaneous encephalitis of rabbits were infected with the disease, although it is irregular.
我们对兔自发性脑炎的材料进行了细菌学和病理组织学检查,但尚未发现本病的特异性细菌,也未发现本病的宏观特征。我们确信这种自发性脑炎不是由细菌引起的,我们认为这种疾病可能是由某种单一的病原体引起的,因为在所有病例中,组织学上都有一些特定的脑组织颗粒的变化。从组织病理变化判断,病原体有嗜神经性倾向。正如Levaditi和他的合作者所认为的那样,这种病原体可能是cucuuli脑虫,但直到现在我们还没有确凿的证据。总之,可以肯定的是,用兔自发性脑炎感染动物的脑乳剂接种的家兔感染了该病,尽管没有规律性。
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引用次数: 0
ON THE FILARIA FROM THE FORMOSAN DOMESTICATED BIRDS 台湾家鸟丝虫病的研究
Pub Date : 1900-01-01 DOI: 10.1292/JVMS1922.13.261
M. Sugimoto
In Northern Formosa (Pref. Taihoku, Shinchiku), subcutaneous tumors occur among young ducks, mostly on the chin, thigh, etc. In the connective tissue of these subcutaneous tumors the author observed a nematode parasite, Oshimaia taiwana (SUGIMOTO, 1919). As this species does not agree with any other species belonging to superfamily Filarioidea, therefore Oshimaia was established as a new genus of the family Phailometridae BAYLIS & DAUBNEY.
在北台湾(台北县,新竹县),皮下肿瘤发生在幼鸭,主要在下巴,大腿等。在这些皮下肿瘤的结缔组织中,作者观察到一种线虫寄生虫,Oshimaia台湾(SUGIMOTO, 1919)。由于该种不属于丝虫总科的任何其他种,因此将Oshimaia作为fililometridae BAYLIS & DAUBNEY的新属建立。
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引用次数: 1
Studien über eine in Manchoukuo seuchenhaft auftretende Hühnerseuche. Mitt. I. Beitrag zur Kenntnis der Symptomatologie bei Geflügelpest 我正试图找出两栖感染上的…挂.2 .对家禽病的症状分析的了解
Pub Date : 1900-01-01 DOI: 10.1292/JVMS1922.17.78
S. Yamagiwa, M. Niwa
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引用次数: 1
期刊
Journal of the Japanese Society of Veterinary Science
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