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STUDIEN ÜBER DIE LOKALANÄSTHESIE UND IHRE ANWENDUNG BEI HAUSTIEREN MIT BESONDERER BERÜCKSICHTIGUNG DER TECHNIK DERSELBEN 关于局部麻醉的研究及其在宠物的运用的技术要特别关注
Pub Date : 1922-12-20 DOI: 10.1292/JVMS1922.1.273
S. Matsuba
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引用次数: 1
ON THE COMPARATIVE STUDY OF NOCARD'S BACILLUS WITH GRAWITZ'S ACNEBACILLUS 诺卡氏芽孢杆菌与格拉维茨痤疮杆菌的比较研究
Pub Date : 1922-12-20 DOI: 10.1292/JVMS1922.1.213
K. Tsuge
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引用次数: 0
ON THE RABICIDAL PROPERTY OF ANTI-RABIES SERUM 抗狂犬病血清的杀虫性能研究
Pub Date : 1922-12-20 DOI: 10.1292/JVMS1922.1.279
S. Kondo
The investigations just outlined indicate that1. The anti-rabies serum from animals artificially immunized possesses a specific rabicidal property, while no other antibodies can be found in it.2. The serum from animals immunized by repeated injections with normal nerve material has a non-specific property against rabic virus. 3. The rabicidal property of serum from naturally immune (refractory) animals can be a direct index of resistance against rabies infection.4. The union of rabic virus with anti-rabies serum takes place in multiple proportion as in the case of toxin and antitoxin. This fact indicates that even a slight degree of resistance against rabies in an individual can be detected by titrating the serum of the individual with a small dose of virus. From a practical point of view, it would be very interesting to indirectly standardize the value of a rabies vaccine by titrating the rabicidal property of serum taken from animals inoculated with the vaccine.5. The rabicidal property of the anti-rabies serum vanishes by heating at 80°C. for one-half hour, while no change takes place in rabicidal power of the serum by heating below 70°C. for onehalf hour.6. The optimum temperature and time for the union of rabic virus with anti-rabies serum are 37°C. and two hours respectively. A somewhat similar result is obtained by storing them at a temperature of from 18°-20°C. for twenty hours in a dark room.7. The protective injection of the anti-rabies serum into guinea-pigs inoculated with rabic virus has given satisfactory results. This may throw a light on the problem of utilizing anti-rabies serum for protective or curative purposes.
刚才概述的调查表明。人工免疫动物的抗狂犬病血清具有特异性的杀狂犬病特性,而在其中没有发现其他抗体。用正常神经物质反复注射免疫动物血清对狂犬病病毒具有非特异性。3.自然免疫(难治)动物血清的杀虫性能可作为狂犬病感染抵抗的直接指标。狂犬病病毒与抗狂犬病血清的结合与毒素与抗毒素的结合呈多倍比例。这一事实表明,通过用小剂量病毒滴定个体的血清,可以检测到个体对狂犬病的抵抗力,即使是轻微的程度。从实用的观点来看,通过滴定接种了狂犬病疫苗的动物血清的杀狂犬病性能来间接地标准化狂犬病疫苗的价值将是非常有趣的。在80℃加热后,抗狂犬病血清的杀虫性能消失。加热至70℃以下时,血清的杀虫能力没有变化。半小时。狂犬病病毒与抗狂犬病血清结合的最佳温度和时间为37℃。分别是两个小时。将它们储存在18°-20°C的温度下也会得到类似的结果。在一个黑暗的房间里呆了20个小时。用抗狂犬血清对感染狂犬病病毒的豚鼠进行保护性注射,取得了满意的效果。这可能有助于解决将抗狂犬病血清用于保护或治疗目的的问题。
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引用次数: 2
RECHERCHES SUR LA SPIROCHAETA LAVERANI BREINL
Pub Date : 1922-12-20 DOI: 10.1292/JVMS1922.1.235
Katsuya Kasai
Nous avons etudie trois varietes Spirochaeta laverani; c-a-d: la variete humaine (Spirochaeta morsus muris), celle des souris sauvages et des souris blanches (Spirochaeta laverani s. muris). En resume, les consequences qui resultent de nos recherches en morphologie, transmissibilite, voies d'elimination et mode d'infection sont les suivants:1°. Spirochaeta laverani est un des plus petits et, a l'ultramicroscope, il apparait sous l'aspect d'une spirale nonflexible, dont la section transversale est, selon toute probabilite, l'ellipse aplatie. Les. tours de spire sont reguliers et serres, et leur nombre varie de II/2 a 7. La longueur du corps spiral est de 1, 6 a 7, 0μ et son epaisseur 0, 6 environ.La microbe possede a chacune de ses extremites un filament long et epais, montrant l'apparence d'une spirale peu serree, dont la longueur est plus longue que celle de son corps (Fig. 1 et 2).2°. Sa dimension diftere un peu selon le genre de variete et la variete des souris blanches la plus grande est 3, 3μ en la longueur moyenne, celle des souris sauvages 3, 1μ et la variete humaine la plus petite n'a seulement que 2, 9μ.3°. Spirochaeta laverani se colore aisement par les colorants usuels, et en particulier tres nettement, par le bleu de Manson, par le Giemsa et par l'hematoxyline ferree de Heidenhain. II ne prend pas le Gram.Pour la constatation de cils de Spirochaeta laverani, la coloration de Giemsa, apres la fixation dans les vapeurs d'acide osmique, et les procede de Fontana-Tribondeau et de Benians sont recommandees. La coloration vitale par le bleu de Manson presente le spirochete colore en mouvement actif, mais elle ne montre pas la construction speciale de son corps.4°. Spirochaeta laverani presente des mouvements de progression tres rapides dus a la rotation active des cils.5°. Ce spirochete parait se reproduire seulement par division transversale.6°. La variete humaine et celle des souris sauvages sont facilement transmissibles a la souris, le rat et le cobaye. La premiere aussi se transmet au jeune chat. Au contraire, la variete des souris blanches he peut pas apparemment infecter le rat adulte et le cobaye, tandis que cette variete est tres virulente pour la souris es le rat jeune. Cependant les animaux, qui resistent a l'inoculation de la derniere variete, peuvent aisement contaminer la souris par l'introduction de leur sang.7°. Passant par le corps des rats jeunes pour dix generations, la variete des souris blanches s'augmente en virulence pour le rat et peut aisement infecter le rat adulte meme. Apres deux passages par les cobayes, la meme variete pouvait aussi se montrer microscopiquement dans le sang circulant de celui de la troisieme generation.8°. La splenectomie fait le rat adulte completement susceptible a la variete des souris blanches et aussi beaucoup plus sensible a celle des souris sauvages.9°. Spirochaeta laverani ne semble pas etre elimine par des crachats, des contenus intestinaux et des urines de l'animal infecte.10°. Nous n
我们研究了三种螺旋藻品种;c-a-d:人类(Spirochaeta morsus muris)、野生老鼠和白老鼠(Spirochaeta laverani s. muris)。综上所述,我们在形态学、传染性、消除途径和感染方式方面的研究结果如下:Spirochaeta laverani是最小的螺旋之一,在超微显微镜下,它看起来像一个不可弯曲的螺旋,其横截面很可能是扁平的椭圆。对于。塔尖是常规的温室,数量从II/2到7不等。螺旋体长度为1.6 ~ 7.0 μ,厚度约为0.6 μ。被附的微生物的每一端都有一根长而厚的细丝,呈松散的螺旋状,比身体的长度长(图1和2)。其大小因品种类型而略有不同,白色小鼠品种平均长度最大为3.3 μ,野生小鼠品种为3.1 μ,最小的人类品种仅为2.9 μ。Spirochaeta laverani可以很容易地用通常的染料着色,特别是用Manson blue, Giemsa和Heidenhain hematoxyline ferree染色。他不收克。对于螺旋藻的睫毛,建议在渗透酸蒸汽中固定后使用Giemsa染色,以及fonana - tribondeau和Benians工艺。曼森蓝色的生命力色彩呈现出活跃运动的螺旋色,但它并没有显示出他身体的特殊结构。由于细胞的主动旋转,Spirochaeta laverani表现出非常快速的前进运动。这种螺旋虫似乎只通过横向分裂繁殖。人类和野生小鼠的品种很容易传播给小鼠、大鼠和豚鼠。第一个也传给了小猫。相比之下,白鼠品种he显然不能感染成年大鼠和豚鼠,而该品种对小鼠和幼大鼠有很强的毒性。然而,对后一种品种的接种有抵抗力的动物很容易通过引入它们的血液污染小鼠。白鼠通过幼龄大鼠体内10代,对大鼠的毒性增加,甚至可以很容易地感染成年大鼠。经过两次实验后,同样的品种也可以在第三代人的血液循环中显微显示出来。脾切除术使成年大鼠对白色小鼠品种完全敏感,对野生小鼠品种更敏感。laverani螺旋体似乎不能通过受感染动物的痰液、肠道内容物和尿液排出。我们无法通过显微镜检查在健康小鼠(45只野生小鼠和9只白小鼠)和自然感染小鼠(2只野生小鼠和6只白小鼠)的粪便中发现类似的螺旋体。
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引用次数: 2
ON A SOLUBLE TOXIN PRODUCED BY BACILLUS CHAUVOEI 一种由芽孢杆菌产生的可溶性毒素
Pub Date : 1922-10-20 DOI: 10.1292/JVMS1922.1.157
K. Okuda
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引用次数: 3
A STUDY IN ACTIVE IMMUNIZATION AGAINST FOWL CHOLERA 禽霍乱主动免疫的研究
Pub Date : 1922-10-20 DOI: 10.1292/JVMS1922.1.151
K. Sakamoto
1. The drying of fowl cholera attenuated, or killed by shaking, drying or heating proved to be of no value as vaccines.2. The organism killed with disinfectants, fowl cholera aggressine and condensed broth culture of the organism, both mono- and polyvalent, gave better results; the production of an abscess at the site of inoculation was, however, a common defect of these vaccines.3. Nucleoproteids, both mono- and polyvalent, gave very satisfactory results, conferring a solid immunity to animals treated with no ill effects.Finally I wish to express my best thanks to Prof. N. NITTA for his valuable suggestions in this work.
1. 干燥的家禽霍乱减毒,或通过摇晃,干燥或加热被证明是没有价值的疫苗。用杀菌剂、禽霍乱侵袭剂和浓缩肉汤培养的病原菌单价和多价杀灭效果较好;然而,在接种部位产生脓肿是这些疫苗的一个共同缺陷。单价和多价核蛋白均产生了非常令人满意的结果,使接受治疗的动物具有坚实的免疫力,没有任何不良反应。最后,我要感谢N. NITTA教授在这项工作中提出的宝贵建议。
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引用次数: 1
EXPERIMENTAL STUDIES ON AVIAN DIPHTHERIA 禽白喉的实验研究
Pub Date : 1922-10-20 DOI: 10.1292/JVMS1922.1.123
N. Nakamura
Although avian diphtheria has long been recognized as an epizootic disease among chickens, and several investigations made by numerous workers in foreign countries since 1873 have been reported, our knowledge of the causal agent is still far from complete. This disease has also become yearly more widespread in this conntry and attention has been directed to it chiefly through the work of investigators rather than by the losses it has occasioned. In 1907, Carnwath concluded from his experimental work that the causal agent of this disease was identical with the virus of chicken pox, since which we have had no other noteworthy information concerning this disease. I have studied, in the first
虽然禽白喉早已被认为是鸡的一种动物传染病,而且自1873年以来在国外许多工作者所作的几次调查也有报道,但我们对致病因子的认识仍然很不完整。这种疾病在这个国家也变得越来越普遍,人们对它的关注主要是通过调查人员的工作,而不是它所造成的损失。1907年,卡纳沃斯从他的实验工作中得出结论,这种疾病的致病因子与水痘病毒相同,此后我们没有关于这种疾病的其他值得注意的信息。我学习过,在第一
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引用次数: 0
STUDIES ON BOVINE INFLUENZA 牛流感的研究
Pub Date : 1922-10-20 DOI: 10.1292/JVMS1922.1.133
H. Futamura
In this Journal, Vol. 1, No. 3, I reported on the occurrence, symptoms and necropsy of some cases of bovine influenza, confirming that in the saliva, nasal discharge, lungs and other organs of an infected anmal a bipolar bacillus is always found, which is highly vilurent against mice, rabbits, sheep and cattle. The serological experiments carried out with the bacilli and the blood serum from infected cattle gave always positive results, consequently rendering it possible to distinguish the normal blood serum from the infected. As regards the treatment, I found that a serum taken from cattle highly immunized against the bacillus has a curative power for the disease. From the facts above mentioned I concluded that the bacillus is closely related with the disease.Fortunately an opportunity has come to me to make further investigations on this subject towards the end of March, last year, occurred among calves and cows in a dairy herd near the city of Tokyo an infectious disease which attacked 14 calves and 23 cows within a course of one month. By reasonable treatments and the application of an immune serum against the bacillus all the infected cows recovered from the disease but these measures were not effective in the calves; thus the number of cases among them increased continually till it reached 22, of which 13 have fallen victims to the. disease.
在本刊第1卷第3期,我报道了一些牛流感病例的发生、症状和尸检,证实在被感染动物的唾液、鼻分泌物、肺和其他器官中总能发现一种双极芽孢杆菌,这种芽孢杆菌对小鼠、兔子、羊和牛有很强的毒性。用杆菌和感染牛的血清进行血清学实验,结果均为阳性,从而使区分正常血清和感染血清成为可能。至于治疗方法,我发现从对这种芽孢杆菌有高度免疫的牛身上提取的血清对这种疾病有疗效。根据上述事实,我得出结论,这种芽孢杆菌与这种疾病密切相关。幸运的是,去年3月底,我有机会对这个问题进行进一步的调查,在东京市附近的一个奶牛场的小牛和奶牛中发生了一种传染病,在一个月内袭击了14头小牛和23头奶牛。通过合理的处理和应用抗菌免疫血清,所有感染的奶牛均痊愈,但这些措施对犊牛无效;因此,其中的病例数不断增加,直至达到22例,其中13例是霍乱的受害者。疾病。
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引用次数: 1
ON THE SPIROCHETES IN SWINE 关于猪的螺旋体
Pub Date : 1922-10-20 DOI: 10.1292/JVMS1922.1.149
Sueichi Nomi, T. Matsuo
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引用次数: 3
ON THE DISINFECTION OF ANIMAL-HAIRS 关于动物毛发的消毒
Pub Date : 1922-06-25 DOI: 10.1292/JVMS1922.1.85
A. Iizuka
(1) Vacu-form apparatus (S. K. Type disinfection apparatus) is good for the disinfection of animal-hairs.(2) The hairs disinfected with this apparatus are comparatively uninjured.(3) I believe that the practice of disinfecting animal-hairs. at the quarantine stations will be attended with good results.
(1)真空式消毒装置(S. K.型消毒装置)对动物毛发的消毒效果较好(2)用这种装置消毒后的毛发相对不受损伤(3)我认为对动物毛发进行消毒的做法是可行的。在检疫站将得到良好的结果。
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引用次数: 0
期刊
Journal of the Japanese Society of Veterinary Science
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