The author carried out bacteriological examination of the vaginal secretion of 200 normal mares, and isolated the following bacteria: the hay bacilli, coli, streptococci and staphylococci. Of these, hay bacilli did not always occur in the standing mare. The percentages of the occurrence of these bacteria as they had been isolated on the common agar were: 84.5% with the coli, 71.5% with the streptococci, 62.0% with the hay balilli and 28.0% with the staphylococci. The streptococci occurred less frequently in the young mares. Both the hemolytic and the nonhemolytic groups of them were isolated, the former was still further identified to belong to either one or the other of the βm, βg and β+ types. The staphlococci consisted of three species, i. e. aureus, albus and orangeus. By saccharolytic test with the 30 strains, isolated, 15 were pathogenic. From 3 cases out of the total 200 mares examined, B. pyocyaneus was isolated.
{"title":"ON THE BACTERIAL FLORA OF THE VAGINAL SECRETION OF THE NORMAL MARE","authors":"S. Umeno","doi":"10.1292/JVMS1922.3.311","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.311","url":null,"abstract":"The author carried out bacteriological examination of the vaginal secretion of 200 normal mares, and isolated the following bacteria: the hay bacilli, coli, streptococci and staphylococci. Of these, hay bacilli did not always occur in the standing mare. The percentages of the occurrence of these bacteria as they had been isolated on the common agar were: 84.5% with the coli, 71.5% with the streptococci, 62.0% with the hay balilli and 28.0% with the staphylococci. The streptococci occurred less frequently in the young mares. Both the hemolytic and the nonhemolytic groups of them were isolated, the former was still further identified to belong to either one or the other of the βm, βg and β+ types. The staphlococci consisted of three species, i. e. aureus, albus and orangeus. By saccharolytic test with the 30 strains, isolated, 15 were pathogenic. From 3 cases out of the total 200 mares examined, B. pyocyaneus was isolated.","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127399393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
1. Eine Autolysin, die bei einem Fall (latent Form) von infektiosen Blutarmut gepruften ist (1918), steht in keiner Bedeutung zur Pathologic der Anamie.2. Der hamolytische Titer der Autolysin fur eigene Blutkorperchen betrug 1:1600 und sie bedurft eines Komplements.3. Die Reaktion tritt bei 37.0°C, 41.0°C oder bei Zimmertemperatur ein, aber im Eiskammer (0-2.0°C) erst nach 20 Stunden.4. Die Autolysin reagiert als Isolysin gegen anderen Pferdeblutkorperchen in etwa 60% der Falle, unabhangig von den Befinden der Tiere und der Titer bezifferte sich 1:80-2000, grosstenteils 1:200-1000.5. Die Autolysin bleibt unverandert durch Erhitzung bei 56.0°C in 30 Minuten, verschwachert sich etwas bei 60.0°C in 30 Minuten und verliert nicht ihre Tatigkeit bei 65.0°C in 15 Minuten.6. Durch intravenose Injektion der von mir nachgewiesenen Hamolysin in den Pferdekorper, in welchem hamolysierbare Blutkorperchen vorhanden sind, konnen die Blutkorperchen nicht zerfallen werden, also tritt keine Anamie auf. Diese Tatsache wurde vielleicht durch Mangelhaft von Komplement im Pferdekorper verursacht.7. Die Resistenz der Blutkorperchen gegen Hamolysin ist ganz unabhangig von der gegen hypotonischen Kochsalzlosung.8. Die Hamolysin steht in keiner Ubereinstimmung mit der Isolysin (Kii) bezuglich ihrer Eigenschaft insbesonders ihrer Widerstandfahigkeit gegen Erhitzung.
{"title":"ÜBER EINE AUTOLYSIN BEIM PFERDE","authors":"Masanori Nagao","doi":"10.1292/JVMS1922.3.261","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.261","url":null,"abstract":"1. Eine Autolysin, die bei einem Fall (latent Form) von infektiosen Blutarmut gepruften ist (1918), steht in keiner Bedeutung zur Pathologic der Anamie.2. Der hamolytische Titer der Autolysin fur eigene Blutkorperchen betrug 1:1600 und sie bedurft eines Komplements.3. Die Reaktion tritt bei 37.0°C, 41.0°C oder bei Zimmertemperatur ein, aber im Eiskammer (0-2.0°C) erst nach 20 Stunden.4. Die Autolysin reagiert als Isolysin gegen anderen Pferdeblutkorperchen in etwa 60% der Falle, unabhangig von den Befinden der Tiere und der Titer bezifferte sich 1:80-2000, grosstenteils 1:200-1000.5. Die Autolysin bleibt unverandert durch Erhitzung bei 56.0°C in 30 Minuten, verschwachert sich etwas bei 60.0°C in 30 Minuten und verliert nicht ihre Tatigkeit bei 65.0°C in 15 Minuten.6. Durch intravenose Injektion der von mir nachgewiesenen Hamolysin in den Pferdekorper, in welchem hamolysierbare Blutkorperchen vorhanden sind, konnen die Blutkorperchen nicht zerfallen werden, also tritt keine Anamie auf. Diese Tatsache wurde vielleicht durch Mangelhaft von Komplement im Pferdekorper verursacht.7. Die Resistenz der Blutkorperchen gegen Hamolysin ist ganz unabhangig von der gegen hypotonischen Kochsalzlosung.8. Die Hamolysin steht in keiner Ubereinstimmung mit der Isolysin (Kii) bezuglich ihrer Eigenschaft insbesonders ihrer Widerstandfahigkeit gegen Erhitzung.","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114846678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ON THE EFFECTS OF CASTRATION UPON THE THYROID GLAND, HYPOPHYSIS, THYMUS AND ADRENALS IN THE ALBINO RAT","authors":"S. Matsuba","doi":"10.1292/JVMS1922.3.169","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.169","url":null,"abstract":"","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124934780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ON THE SEROLOGICAL DIFFERENTIATION OF B. ABORTUS AND B. MELITENSIS","authors":"H. Futamura","doi":"10.1292/JVMS1922.3.127","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.127","url":null,"abstract":"","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"127 23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123586938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There are, as is known, several methods for preparing serum to be used for therapeutic and diagnostic purposes, but the clotting process and the defibrination followed by centrifugation have widely been employed with noticeable efficiency in practical work. While by the former method clear and sterile serum is obtainable, simply allowing the blood to clot, the latter gives higher percentages in the gain of serum. It often occurs, however, by employing the latter method that the material is accidentally contaminated during the process of centrifugation and the serum obtained becomes quite unfit for use. In order to prevent the accidental contamination and to obtain a large possible amount of sterile seerum, several kinds of apparatus have atreacly been designed. As it will be of great interest to know which is the best method, which is the best apparatus and in what condition the serum gain is largest, I have made some experiments, employing the known methods and apparatuses, to determine, as a first step, the relation between the yield of serum and the amount of bleeding, slight starvation, atmospheric pressure, temperature, size and shape of glass jar, etc. The apparatuses used in my experiments are:1) The apparatus used in the Pasteur Institute, Paris.2) The bucket for blood clotting designed by the Laboratory of the Indian Civil Veterinary Department.3) Latapie's apparatus.The results obtained are as follows:1) The yield of serum depends upon the individuality of animals and the total sum of the serum which is obtained from the usual clot at 2-day-intervals during 9 days amounts to 41-64% of the whole blood drawn.2) The percentage of serum from the first bleeding (4000c.c.) was lower by 6.5% than that from the second which, being same in the quantity of blood, took place 2 days later.No influence of an atmospheric pressure and slight starvation upon the yield of serum has been observed.4) The adequate temperature for separation of serum is about 20°C.5) The amount of serum obtained is proportional to the height of glass jar.6) The compressive method employed in the Veterinary Laboratory at Buitenzorg (Java) is most applicable in horse and swine blood. According to the experiments, this method requires no complicated apparatus, shortens the time necessary for collec-ting serum, gives serum 4-13% more than that obtained from the usual clot, and the serum is guite free from hemoglobin. As for the bucket of Indian Civil Veterinary Laboratory, it seems to be more favourable to use it for the preparation of serum from cattle blood, though the serum is often found in an impure state, slightly mixed with red blood corpuscles.
{"title":"COMPARATIVE STUDIES ON THE METHODS FOR PREPARING SERUM","authors":"H. Oguni","doi":"10.1292/JVMS1922.3.81","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.81","url":null,"abstract":"There are, as is known, several methods for preparing serum to be used for therapeutic and diagnostic purposes, but the clotting process and the defibrination followed by centrifugation have widely been employed with noticeable efficiency in practical work. While by the former method clear and sterile serum is obtainable, simply allowing the blood to clot, the latter gives higher percentages in the gain of serum. It often occurs, however, by employing the latter method that the material is accidentally contaminated during the process of centrifugation and the serum obtained becomes quite unfit for use. In order to prevent the accidental contamination and to obtain a large possible amount of sterile seerum, several kinds of apparatus have atreacly been designed. As it will be of great interest to know which is the best method, which is the best apparatus and in what condition the serum gain is largest, I have made some experiments, employing the known methods and apparatuses, to determine, as a first step, the relation between the yield of serum and the amount of bleeding, slight starvation, atmospheric pressure, temperature, size and shape of glass jar, etc. The apparatuses used in my experiments are:1) The apparatus used in the Pasteur Institute, Paris.2) The bucket for blood clotting designed by the Laboratory of the Indian Civil Veterinary Department.3) Latapie's apparatus.The results obtained are as follows:1) The yield of serum depends upon the individuality of animals and the total sum of the serum which is obtained from the usual clot at 2-day-intervals during 9 days amounts to 41-64% of the whole blood drawn.2) The percentage of serum from the first bleeding (4000c.c.) was lower by 6.5% than that from the second which, being same in the quantity of blood, took place 2 days later.No influence of an atmospheric pressure and slight starvation upon the yield of serum has been observed.4) The adequate temperature for separation of serum is about 20°C.5) The amount of serum obtained is proportional to the height of glass jar.6) The compressive method employed in the Veterinary Laboratory at Buitenzorg (Java) is most applicable in horse and swine blood. According to the experiments, this method requires no complicated apparatus, shortens the time necessary for collec-ting serum, gives serum 4-13% more than that obtained from the usual clot, and the serum is guite free from hemoglobin. As for the bucket of Indian Civil Veterinary Laboratory, it seems to be more favourable to use it for the preparation of serum from cattle blood, though the serum is often found in an impure state, slightly mixed with red blood corpuscles.","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"252 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117295014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aus den obigen Resultaten, konnen die Veranderungen der roten Blutkorperchen zufolge von Schwankung der Korpertemperatur wahrend des Krankheitsverlaufes wie folgt erklart und zusammengefasst werden.1. Fieberform.Die 10 Versuchspferde erkrankten nach verschiedenen Inkubationsstadien d. h. von 6 bis 21 Tagen nach Impfung des virsushaltigen Blutes und zeigten die alle eigentliche Korpertemperaturerhohung. Wenngleich die Temperaturerhohungen in ersten Anfallen meist so hoch wie 40.0°C oder daruber erreichen, doch sind in einigen Fallen (Nr. 4, Nr. 5 und Nr. 7) ganz niedrig geblieben. Der erste Anfall dauert meistens 4 bis 7 Tage lang, aber bisweilen 10 Tage lang bei einer geringeren wie in Nr. 5 und 3 Wochen lang bei einer heftigen Korpertemperaturerhohung wie in Nr. 3. Das Auftreten des Zwischenstadiums nach dem ersten Anfall war verschiedenartig. In den meisten Fallen kehrte die Temperatur einmal zu normaler zuruck und dann trat der zweite Anfall ein. Ganz interessant war es aber noch solche Fallen zu beobachten, wo sich die Temperatur, wie in Nr. 1, 2 Wochen lang um 38.0° bis 39.0°C anhielte oder ganz plotzlich auftretende auffallende Steigerung zeigte. Die Dauer des Zwischenstadium ist ganz verschieden. In Nr. 3, Nr. 4 und Nr. 6 ist das zweite Anfall jeden 2 Tage, und in Nr. 5 und 8 jeden 5 Tage wiederholt aufgetreten. In Nr. 7 ist aber die Dauer 7 Tage und in Nr. 2 17 Tage lang gewesen. Der zweite Anfall erscheint sich immer deutlich, und steigt Korpertemperatur haufig auf etwa 41.0°C und dauert von 5 bis 6 Tage lang. Aber kann man auch die Falle beobachten, wo eine hohere Temperatur nur halben Tag wie am 16. in Nr. 5 dauerte oder sich ein unregelmassiges geringeres Fieber sich anhielte. Wahrend einerseits z. B. in Nr. 4 und 8 der Anfall im Laufe des zweiten Zwischenstadiums einem vollkommenen fieberiosen Zustand zukam, beobachtete man anderseits die Falle, wo sich Fieber in geringerem Grade anhielten und haufig zu dritten Anfallen ubergegangen sind. Gunstige Prognosen andeutend, sind die Anfalle grosstenteils aber allmahlich undeutlicher und die Kranken ganz fieberlos geworden.2. Die Zahlen-Veranderung der roten Blutkorperchen.Im allgenimen fangen die rote Blutkorperchen an zu vermindern Wahrend des Anfangsstadiums der Erkrankung und zwar meistens in den ersten 4 Tagen, bisweilen aber in den 9. bis 13. Krankheitstagen. Im Falle, wo sich eine tuchtige Korpertemperatursteigerung im Anfangsstadium erscheint, ist die Veranderung bemerkbar deutlich. Aber in anderen Fallen sind so geringe, ja sogar keine Veranderungen beobachtet worden. In Nr. 7 ist z. B. eine geringere Temperaturerhohung wahrend der ersten 3 Krankheitstage beobachtet worden, liess sich fast keine Veranderung an der Blutkorperchenzahl erwiesen und erst am 15. Krankheitstage d. h. am 2 Tage des zweiten Anfalls richtete sich die Rotenzahlkurve nach unten. Wie aus obigen ersichtlich, steht der Verminderungsgrad des roten Blutkorperchens immer im Verhaltnis zu der Hohe der Korpertemperat
{"title":"BEITRÄGE ZUR KENNTNIS VON DER PATHOLOGISCHEN VERÄNDERUNG DER ROTEN BLUTKÖRPERCHEN BEI DER INFEKTIÖSEN BLUTARMUT DER PFERDE","authors":"Masanori Nagao","doi":"10.1292/JVMS1922.3.99","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.99","url":null,"abstract":"Aus den obigen Resultaten, konnen die Veranderungen der roten Blutkorperchen zufolge von Schwankung der Korpertemperatur wahrend des Krankheitsverlaufes wie folgt erklart und zusammengefasst werden.1. Fieberform.Die 10 Versuchspferde erkrankten nach verschiedenen Inkubationsstadien d. h. von 6 bis 21 Tagen nach Impfung des virsushaltigen Blutes und zeigten die alle eigentliche Korpertemperaturerhohung. Wenngleich die Temperaturerhohungen in ersten Anfallen meist so hoch wie 40.0°C oder daruber erreichen, doch sind in einigen Fallen (Nr. 4, Nr. 5 und Nr. 7) ganz niedrig geblieben. Der erste Anfall dauert meistens 4 bis 7 Tage lang, aber bisweilen 10 Tage lang bei einer geringeren wie in Nr. 5 und 3 Wochen lang bei einer heftigen Korpertemperaturerhohung wie in Nr. 3. Das Auftreten des Zwischenstadiums nach dem ersten Anfall war verschiedenartig. In den meisten Fallen kehrte die Temperatur einmal zu normaler zuruck und dann trat der zweite Anfall ein. Ganz interessant war es aber noch solche Fallen zu beobachten, wo sich die Temperatur, wie in Nr. 1, 2 Wochen lang um 38.0° bis 39.0°C anhielte oder ganz plotzlich auftretende auffallende Steigerung zeigte. Die Dauer des Zwischenstadium ist ganz verschieden. In Nr. 3, Nr. 4 und Nr. 6 ist das zweite Anfall jeden 2 Tage, und in Nr. 5 und 8 jeden 5 Tage wiederholt aufgetreten. In Nr. 7 ist aber die Dauer 7 Tage und in Nr. 2 17 Tage lang gewesen. Der zweite Anfall erscheint sich immer deutlich, und steigt Korpertemperatur haufig auf etwa 41.0°C und dauert von 5 bis 6 Tage lang. Aber kann man auch die Falle beobachten, wo eine hohere Temperatur nur halben Tag wie am 16. in Nr. 5 dauerte oder sich ein unregelmassiges geringeres Fieber sich anhielte. Wahrend einerseits z. B. in Nr. 4 und 8 der Anfall im Laufe des zweiten Zwischenstadiums einem vollkommenen fieberiosen Zustand zukam, beobachtete man anderseits die Falle, wo sich Fieber in geringerem Grade anhielten und haufig zu dritten Anfallen ubergegangen sind. Gunstige Prognosen andeutend, sind die Anfalle grosstenteils aber allmahlich undeutlicher und die Kranken ganz fieberlos geworden.2. Die Zahlen-Veranderung der roten Blutkorperchen.Im allgenimen fangen die rote Blutkorperchen an zu vermindern Wahrend des Anfangsstadiums der Erkrankung und zwar meistens in den ersten 4 Tagen, bisweilen aber in den 9. bis 13. Krankheitstagen. Im Falle, wo sich eine tuchtige Korpertemperatursteigerung im Anfangsstadium erscheint, ist die Veranderung bemerkbar deutlich. Aber in anderen Fallen sind so geringe, ja sogar keine Veranderungen beobachtet worden. In Nr. 7 ist z. B. eine geringere Temperaturerhohung wahrend der ersten 3 Krankheitstage beobachtet worden, liess sich fast keine Veranderung an der Blutkorperchenzahl erwiesen und erst am 15. Krankheitstage d. h. am 2 Tage des zweiten Anfalls richtete sich die Rotenzahlkurve nach unten. Wie aus obigen ersichtlich, steht der Verminderungsgrad des roten Blutkorperchens immer im Verhaltnis zu der Hohe der Korpertemperat","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124772823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CONTRIBUTIONS TO THE EXPERIMENTAL STUDY ON THE PREPARATION OF THE BLACKLEG PRECIPITIN SERUM","authors":"Yutaka Kawamura","doi":"10.1292/JVMS1922.3.113","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.113","url":null,"abstract":"","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133725506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ON THE DISINFECTION OF ANIMAL BONES","authors":"A. Iizuka, T. Watanuki","doi":"10.1292/JVMS1922.3.1","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.1","url":null,"abstract":"","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124257738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ON THE IODIZED SWINE ERYSIPELAS VACCINE","authors":"S. Fujimura","doi":"10.1292/jvms1922.3.17","DOIUrl":"https://doi.org/10.1292/jvms1922.3.17","url":null,"abstract":"","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"2 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120814165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In an earlier report (see this journal Vol. I, No. 1) the writer referred to the results of his experiments carried out to investigate the nature of lumbar paralysis occurring among the noble races of goat imported here from Switzerland and their offsprings, and arrived at the conclusion that this disease is an infectious disease anatomically characterized by meningitis spinalis and sclerosis spinalis, its causal organism being a streptococcus.In the present paper details are given of further experiments on this disease. The lesions observed by him consist chiefly of infarnmation of the spinal cord, namely-leptomeningitis serosa et lymphocytica and myelitis circumscripta ventralis with myelomalacia periarterialis in the white matter in earlier stages, while in chronic cases leptomeningitis fibroplastica and gliosis sclerotica spinalis with periarteriitis fibrosa are found. He demonstrated often in the brain leptomeningitis basilaris serosa et lymphocytica, and encephalitis lymphocytica or encephalomalacia perlarterlalrs in the white matter near the ventricles.The streptococcus mentioned in the previous paper was isolated from the cerebro-spinal fluid in all twenty-four cases bacteriologically examined. The organism is a coccus about 0.6-0.8μ in diameter, occurring in pairs or in short chains, Gram-positive, and does not grow well on the artificial media; gelatin is not liquefied, milk not coagulated, and no indol produced. The organism causes hemolysis when grown on blood agar plates, tiny colonies being surrounded by clear zones. The following carbohydrates are fermented: arabinose, dextrin, galactose, glucose, glycerin, inulin, lactose, levulose, maltose, mannite, mannose, raffinose, rhamnose, saccharose, salicin, soluble starch, and sorbite.Twenty healthy goats inoculated intraspinally with cultures of this organism showed symptoms, and anatomical and histological changes similar to those of the natural cases, especially so when the resistance of animals is lessened before the inoculation by bleeding, administration of cresin, or intravenous injection of the serum obtained by immunizing the rabbit with central nervous system of the goat.Results of experiments regarding the reactions of immunity, such as agglutination, precipitation, and complement-fixation, were also satisfactory.In conclusion, the writer emphasizes the streptoccus to be the causal organism of this disease from a bacteriological and immunological point of view, giving to this organism the name Streptococcus caprinus, owing to some differences existing between this and other pathogenic streptococci.
{"title":"FURTHER STUDIES ON THE NATURE OF LUMBAR PARALYSIS IN THE GOAT","authors":"O. Emoto","doi":"10.1292/JVMS1922.3.37","DOIUrl":"https://doi.org/10.1292/JVMS1922.3.37","url":null,"abstract":"In an earlier report (see this journal Vol. I, No. 1) the writer referred to the results of his experiments carried out to investigate the nature of lumbar paralysis occurring among the noble races of goat imported here from Switzerland and their offsprings, and arrived at the conclusion that this disease is an infectious disease anatomically characterized by meningitis spinalis and sclerosis spinalis, its causal organism being a streptococcus.In the present paper details are given of further experiments on this disease. The lesions observed by him consist chiefly of infarnmation of the spinal cord, namely-leptomeningitis serosa et lymphocytica and myelitis circumscripta ventralis with myelomalacia periarterialis in the white matter in earlier stages, while in chronic cases leptomeningitis fibroplastica and gliosis sclerotica spinalis with periarteriitis fibrosa are found. He demonstrated often in the brain leptomeningitis basilaris serosa et lymphocytica, and encephalitis lymphocytica or encephalomalacia perlarterlalrs in the white matter near the ventricles.The streptococcus mentioned in the previous paper was isolated from the cerebro-spinal fluid in all twenty-four cases bacteriologically examined. The organism is a coccus about 0.6-0.8μ in diameter, occurring in pairs or in short chains, Gram-positive, and does not grow well on the artificial media; gelatin is not liquefied, milk not coagulated, and no indol produced. The organism causes hemolysis when grown on blood agar plates, tiny colonies being surrounded by clear zones. The following carbohydrates are fermented: arabinose, dextrin, galactose, glucose, glycerin, inulin, lactose, levulose, maltose, mannite, mannose, raffinose, rhamnose, saccharose, salicin, soluble starch, and sorbite.Twenty healthy goats inoculated intraspinally with cultures of this organism showed symptoms, and anatomical and histological changes similar to those of the natural cases, especially so when the resistance of animals is lessened before the inoculation by bleeding, administration of cresin, or intravenous injection of the serum obtained by immunizing the rabbit with central nervous system of the goat.Results of experiments regarding the reactions of immunity, such as agglutination, precipitation, and complement-fixation, were also satisfactory.In conclusion, the writer emphasizes the streptoccus to be the causal organism of this disease from a bacteriological and immunological point of view, giving to this organism the name Streptococcus caprinus, owing to some differences existing between this and other pathogenic streptococci.","PeriodicalId":101505,"journal":{"name":"Journal of the Japanese Society of Veterinary Science","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1924-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128856122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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