Pub Date : 2023-10-04DOI: 10.33808/clinexphealthsci.1347081
Ömer AYDINER, Hüseyin Kemal RAŞA
Objective: The best option for treating high-risk patients with acute cholecystitis is still being determined. We evaluated our high-risk acute cholecystitis patients in whom we preferred percutaneous cholecystostomy and aimed to determine whether this approach was safe and feasible.
Methods: We retrospectively reviewed our 71 patients in whom we performed percutaneous cholecystostomy between May 2019 and July 2023. All procedures were performed with local anaesthesia under ultrasonographic guidance via the transhepatic route. The catheters were removed when the signs of acute cholecystitis were significantly regressed or when the catheters were found to be ineffective. The catheters of those eligible for surgery were removed during the operations.
Results: All procedures were successful without failure, and no significant complications developed in the post-intervention period. Pain at the catheter insertion site (20 patients) was the leading minor complication, and in one patient, bilioma was detected and percutaneously drained. The procedure was ineffective in 7 patients (9.85%), and the catheters were removed. In 22 patients (31%), interval cholecystectomy surgery was performed. In the subgroup of patients whose catheters were adequate and were not operated (5 patients), the catheters were removed after an average of 27.2 days. The mean length of stay was 9.6 days, and four patients died (5.6%) during the index hospitalization.
Conclusion: Our findings suggest that percutaneous cholecystostomy is a feasible, safe and highly effective treatment option for acute cholecystitis in high-risk patients.
{"title":"Percutaneous Cholecystostomy is a Feasible and Safe Option for High-Risk Acute Cholecystitis Patients","authors":"Ömer AYDINER, Hüseyin Kemal RAŞA","doi":"10.33808/clinexphealthsci.1347081","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1347081","url":null,"abstract":"Objective: The best option for treating high-risk patients with acute cholecystitis is still being determined. We evaluated our high-risk acute cholecystitis patients in whom we preferred percutaneous cholecystostomy and aimed to determine whether this approach was safe and feasible. 
 Methods: We retrospectively reviewed our 71 patients in whom we performed percutaneous cholecystostomy between May 2019 and July 2023. All procedures were performed with local anaesthesia under ultrasonographic guidance via the transhepatic route. The catheters were removed when the signs of acute cholecystitis were significantly regressed or when the catheters were found to be ineffective. The catheters of those eligible for surgery were removed during the operations. 
 Results: All procedures were successful without failure, and no significant complications developed in the post-intervention period. Pain at the catheter insertion site (20 patients) was the leading minor complication, and in one patient, bilioma was detected and percutaneously drained. The procedure was ineffective in 7 patients (9.85%), and the catheters were removed. In 22 patients (31%), interval cholecystectomy surgery was performed. In the subgroup of patients whose catheters were adequate and were not operated (5 patients), the catheters were removed after an average of 27.2 days. The mean length of stay was 9.6 days, and four patients died (5.6%) during the index hospitalization. 
 Conclusion: Our findings suggest that percutaneous cholecystostomy is a feasible, safe and highly effective treatment option for acute cholecystitis in high-risk patients.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-26DOI: 10.33808/clinexphealthsci.1345763
Alev BAKIR KAYI, Benan MÜSELLİM
Objective: Mortality studies are interpreted by considering comorbid diseases related to the main disease. Existence, number, and type of comorbid diseases can have an important effect on prognosis. There are various comorbidity indices to include the effects of comorbid diseases in the model. With a new perspective, we aimed to emphasize the importance of evaluating the combination of comorbid diseases in cancer survival.
Methods: Retrospective cohort, data were collected from cases with Non-Small Cell Lung Cancer treated in Department of Chest Diseases. Initially, the effects of their comorbid diseases on the duration of survival were calculated with univariate analysis, then examined according to number of comorbidities, lastly their specific combinations' Hazar Ratio were calculated with Cox multivariate analysis. The most used comorbid indices in the literature were also included.
Results: Out of 247 non-small cell lung cancer (NSCLC) cases analysis, 220 (89%) were men. Median duration of follow-up was 277 days, at the end of the follow-up 197 cases had died. HR of two comorbid diseases in cases was 1.80, but 59.52 for the combination of “diabetes and interstitial lung disease” and 3.76 for “diabetes and previously cancer”. Existing comorbid indices had no significant effect on survival time (p:0.684; 0.101; 0.273; 0.567, respectively).
Conclusion: We have offered a new perspective which takes into comorbid diseases related to main disease and specially their combinations when the risk is estimated in survival research. Accurate assessments of the list of comorbid diseases related to main disease hold significant importance in advancing this field.
{"title":"A New Perspective on the Evaluation of Comorbidity Indices on Survival in Non-Small Cell Lung Cancer","authors":"Alev BAKIR KAYI, Benan MÜSELLİM","doi":"10.33808/clinexphealthsci.1345763","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1345763","url":null,"abstract":"Objective: Mortality studies are interpreted by considering comorbid diseases related to the main disease. Existence, number, and type of comorbid diseases can have an important effect on prognosis. There are various comorbidity indices to include the effects of comorbid diseases in the model. With a new perspective, we aimed to emphasize the importance of evaluating the combination of comorbid diseases in cancer survival.
 Methods: Retrospective cohort, data were collected from cases with Non-Small Cell Lung Cancer treated in Department of Chest Diseases. Initially, the effects of their comorbid diseases on the duration of survival were calculated with univariate analysis, then examined according to number of comorbidities, lastly their specific combinations' Hazar Ratio were calculated with Cox multivariate analysis. The most used comorbid indices in the literature were also included.
 Results: Out of 247 non-small cell lung cancer (NSCLC) cases analysis, 220 (89%) were men. Median duration of follow-up was 277 days, at the end of the follow-up 197 cases had died. HR of two comorbid diseases in cases was 1.80, but 59.52 for the combination of “diabetes and interstitial lung disease” and 3.76 for “diabetes and previously cancer”. Existing comorbid indices had no significant effect on survival time (p:0.684; 0.101; 0.273; 0.567, respectively).
 Conclusion: We have offered a new perspective which takes into comorbid diseases related to main disease and specially their combinations when the risk is estimated in survival research. Accurate assessments of the list of comorbid diseases related to main disease hold significant importance in advancing this field.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135721389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The present study was aimed to evaluate radiographically the effect of orally administered vitamin D3 on guided bone regeneration in calvarial critical size defects (CSD) in rats.
Methods: Two calvarial CSD were created in 12 male Sprague-Dawley rats. One of the defects was left empty (E defect), while the other one was treated with deproteinized bovine bone graft and collagen-based resorbable membrane (GM-filled defect). Following surgical intervention, rats were randomly assigned into two groups; the control group was administered distilled water, and the test group was treated with 2 µg /kg vitamin D3 by gavage once a day for 8 weeks. Radiological images were obtained from rats on 4th and 8th weeks. The area fraction of newly formed osteoid was determined using Image Fiji Analysis Software.
Results: The percentages of area fraction in the GM-filled defects were statistically higher than the E defects in both study groups at 4th and 8th weeks (p
{"title":"Radiographic Evaluation of the Effect of Vitamin D3 Supplementation on Regeneration of Calvarial Bone Defects in Rats","authors":"Gülce Nil VARLIHAN, Ömer Birkan AĞRALI, Hatice Selin YILDIRIM, Sibel DEMİRCİ DELİPINAR, Leyla KURU, Hafize ÖZTÜRK ÖZENER","doi":"10.33808/clinexphealthsci.1262852","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1262852","url":null,"abstract":"Aim: The present study was aimed to evaluate radiographically the effect of orally administered vitamin D3 on guided bone regeneration in calvarial critical size defects (CSD) in rats.
 Methods: Two calvarial CSD were created in 12 male Sprague-Dawley rats. One of the defects was left empty (E defect), while the other one was treated with deproteinized bovine bone graft and collagen-based resorbable membrane (GM-filled defect). Following surgical intervention, rats were randomly assigned into two groups; the control group was administered distilled water, and the test group was treated with 2 µg /kg vitamin D3 by gavage once a day for 8 weeks. Radiological images were obtained from rats on 4th and 8th weeks. The area fraction of newly formed osteoid was determined using Image Fiji Analysis Software. 
 Results: The percentages of area fraction in the GM-filled defects were statistically higher than the E defects in both study groups at 4th and 8th weeks (p","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135721401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-18DOI: 10.33808/clinexphealthsci.1195447
Y. Kasımoğlu, S. C. İlisulu, C. Baysan, M. Koruyucu, F. Seymen
Objective: The COVID-19 pandemic has deeply affected the entire world. This study aims to evaluate Turkish dentists’ awareness of and protective measures against COVID-19 infection. Methods: A web-based questionnaire consisting of 35 closed-ended and multiple-choice questions was prepared according to Turkish Dental Association guidelines. The questionnaire was divided into three domains: demographic data, precautionary measures, and attitude. Ethical clearance was obtained from the Istanbul University institutional review board. questionnaire was sent to the dentists registered with the Turkish Dental Association. The minimum sample size was calculated as 756 individuals. The Chi-Square test was used to evaluate the difference for categorical variables. Statistical significance was accepted as p< .05. Results: A total of nine hundred and ninety-seven questionnaires was analyzed. Five hundred and sixty-three respondents (56.5%) were general dentists, and 434 (43.5%) were specialists. Seven hundred and thirty-five (73.7%) dentists were found to wear disposable gowns, N95/FFP2 masks, and face shields. About half (48.1%) were confident of avoiding infection. Twenty-one (2.1%) subjects were SARS-Cov-2 positive. A majority of both dentists who had COVID-19 (71.4%) and dentists who did not have it (92.7%) agreed that COVID-19 is an occupational risk (p< .001). Conclusion: Although nearly two-thirds of the respondents reported using personal protective equipment, greater precautionary measures should be taken by dental staff to protect the patients from COVID-19 and other contagious diseases.
{"title":"Awareness of the Protective Measures Against Covid-19 among Turkish Dentists: A Questionnaire Survey","authors":"Y. Kasımoğlu, S. C. İlisulu, C. Baysan, M. Koruyucu, F. Seymen","doi":"10.33808/clinexphealthsci.1195447","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1195447","url":null,"abstract":"Objective: The COVID-19 pandemic has deeply affected the entire world. This study aims to evaluate Turkish dentists’ awareness of and protective measures against COVID-19 infection. Methods: A web-based questionnaire consisting of 35 closed-ended and multiple-choice questions was prepared according to Turkish Dental Association guidelines. The questionnaire was divided into three domains: demographic data, precautionary measures, and attitude. Ethical clearance was obtained from the Istanbul University institutional review board. questionnaire was sent to the dentists registered with the Turkish Dental Association. The minimum sample size was calculated as 756 individuals. The Chi-Square test was used to evaluate the difference for categorical variables. Statistical significance was accepted as p< .05. Results: A total of nine hundred and ninety-seven questionnaires was analyzed. Five hundred and sixty-three respondents (56.5%) were general dentists, and 434 (43.5%) were specialists. Seven hundred and thirty-five (73.7%) dentists were found to wear disposable gowns, N95/FFP2 masks, and face shields. About half (48.1%) were confident of avoiding infection. Twenty-one (2.1%) subjects were SARS-Cov-2 positive. A majority of both dentists who had COVID-19 (71.4%) and dentists who did not have it (92.7%) agreed that COVID-19 is an occupational risk (p< .001). Conclusion: Although nearly two-thirds of the respondents reported using personal protective equipment, greater precautionary measures should be taken by dental staff to protect the patients from COVID-19 and other contagious diseases.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139339223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-14DOI: 10.33808/clinexphealthsci.1130449
Büşra DİNCER, Fatma ATALAY, Arzu TATAR
Objective: Ototoxicity is cellular damage caused by the use of solid treatments as chemotherapeutics in critical illnesses like cancer. The generation of free radicals is linked to fluctuating hearing loss caused by chemotherapeutics. Antioxidants can help to prevent ototoxicity-related oxidative damage. Carvone (CVN) is a monoterpene with excellent antioxidant properties that protect against oxidative damage. This study investigates the biochemical and functional aspects of CVN’s putative otoprotective mechanisms against paclitaxel (PCX)-induced ototoxicity.
Methods: 24 Wistar albino rats were assigned into four different groups: Control, CVN, PCX, and PCX+CVN. Once a week, the control group received saline. The PCX group received 5 mg/kg PCX intraperitoneally once a week (4 times). Once a week, the CVN group received 50 mg/kg intraperitoneally. The PCX+ CVN group received 5 mg/kg PCX followed by 5 mg/kg CVN once a week. All animals were subjected to deterioration product otoacoustic emission testing before (day 0) and after drug administration (day 23).
Results: PCX showed an ototoxic effect by weakening otoacoustic emission values. PCX leads to significant otoacoustic emission value shifts ameliorated by CVN co-treatment (for 2000Hz p< .001, for 4000 levels p< .01, for 6000Hz p< .001, and for 8000 Hz p< .01 in PCX+CVN group). Furthermore, the PCX group had significantly greater malondialdehyde levels and significantly lower glutathione levels in the cochlear tissues, compared to the other groups. Co-administered CVN with PCX reversed these effects, making oxidative stress parameters close to those of the control group (for GSH levels p< .001, for MDA levels p< .01 in the PCX+CVN group).
Conclusion: According to the findings, CVN appears to preserve cochlear function in rats against the disruptive effects of PCX.
{"title":"Otoprotective Mechanisms of Carvone As An Antioxidant Agent Against Ototoxic Damage Caused By Paclitaxel","authors":"Büşra DİNCER, Fatma ATALAY, Arzu TATAR","doi":"10.33808/clinexphealthsci.1130449","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1130449","url":null,"abstract":"Objective: Ototoxicity is cellular damage caused by the use of solid treatments as chemotherapeutics in critical illnesses like cancer. The generation of free radicals is linked to fluctuating hearing loss caused by chemotherapeutics. Antioxidants can help to prevent ototoxicity-related oxidative damage. Carvone (CVN) is a monoterpene with excellent antioxidant properties that protect against oxidative damage. This study investigates the biochemical and functional aspects of CVN’s putative otoprotective mechanisms against paclitaxel (PCX)-induced ototoxicity.
 Methods: 24 Wistar albino rats were assigned into four different groups: Control, CVN, PCX, and PCX+CVN. Once a week, the control group received saline. The PCX group received 5 mg/kg PCX intraperitoneally once a week (4 times). Once a week, the CVN group received 50 mg/kg intraperitoneally. The PCX+ CVN group received 5 mg/kg PCX followed by 5 mg/kg CVN once a week. All animals were subjected to deterioration product otoacoustic emission testing before (day 0) and after drug administration (day 23).
 Results: PCX showed an ototoxic effect by weakening otoacoustic emission values. PCX leads to significant otoacoustic emission value shifts ameliorated by CVN co-treatment (for 2000Hz p< .001, for 4000 levels p< .01, for 6000Hz p< .001, and for 8000 Hz p< .01 in PCX+CVN group). Furthermore, the PCX group had significantly greater malondialdehyde levels and significantly lower glutathione levels in the cochlear tissues, compared to the other groups. Co-administered CVN with PCX reversed these effects, making oxidative stress parameters close to those of the control group (for GSH levels p< .001, for MDA levels p< .01 in the PCX+CVN group).
 Conclusion: According to the findings, CVN appears to preserve cochlear function in rats against the disruptive effects of PCX.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134912212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The objective of this study was to investigate clinical effect of topically administered hyaluronic acid (HA) mouthwash on healing of secondary palatal wound in diabetic (D) rats.
Methods: 60 Wistar albino male rats were divided into D and non-diabetic (ND) groups. Diabetes was induced to 30 randomly selected rats by initially administering 110 mg/kg of nicotinamide intraperitoneally, followed by 15 min of intraperitoneal injection of 65 mg/kg of streptozotocin solution. 5 mm excisional wounds were made in the centre of the palate. After that, 6 animals from each group were sacrificed. Then, both groups were subdivided into two groups: 0.12% HA mouthwash and saline (S) (n=12 per group), depending on the agent to be administered to the wound area (WA). On days 7 and 14, six rats from each group were sacrificed, and the WAs were measured through photographic measurements utilizing Image J software.
Results: The WA decreased with time in each group (p
{"title":"Evaluation of the Clinical Effect of Hyaluronic Acid Mouthwash on Palatal Secondary Wound Healing in Diabetic Rats","authors":"Ezgi AKÇE, Sibel DEMİRCİ DELİPINAR, Leyla KURU, Hatice Selin YILDIRIM","doi":"10.33808/clinexphealthsci.1258371","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1258371","url":null,"abstract":"Objective: The objective of this study was to investigate clinical effect of topically administered hyaluronic acid (HA) mouthwash on healing of secondary palatal wound in diabetic (D) rats. 
 Methods: 60 Wistar albino male rats were divided into D and non-diabetic (ND) groups. Diabetes was induced to 30 randomly selected rats by initially administering 110 mg/kg of nicotinamide intraperitoneally, followed by 15 min of intraperitoneal injection of 65 mg/kg of streptozotocin solution. 5 mm excisional wounds were made in the centre of the palate. After that, 6 animals from each group were sacrificed. Then, both groups were subdivided into two groups: 0.12% HA mouthwash and saline (S) (n=12 per group), depending on the agent to be administered to the wound area (WA). On days 7 and 14, six rats from each group were sacrificed, and the WAs were measured through photographic measurements utilizing Image J software.
 Results: The WA decreased with time in each group (p","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135887198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.33808/clinexphealthsci.1033882
Tülin BAYRAK, Gülsen ŞENER, Emel SAĞLAM GÖKMEN, Ahmet BAYRAK
Objective: Abnormal immune inflammatory response and cytokine storm play an important role on the aspect of increasing mortality in Covid-19. We aimed to investigate whether the Platelet Activating Factor Acetylhydrolase activity (PAF-AH) and hematological parameters have prognostic and predictive value in determining the disease severity.
Methods: A total of 84 Covid-19 patients, 52 of whom were hospitalized in the ward and 32 in the intensive care unit (ICU), and 38 control patients were included in this study.
Results: Lymphocyte and serum albumin levels were significantly lower (p < .001) and age, neutrophils, CRP, procalcitonin, LDH, INR, D-dimer levels were significantly higher (p < .001) in Covid-19 patients compared to the control group. ICU patients had significantly lower (p < .001) lymphocyte, albumin values and significantly higher (p < .001) age, leukocyte, neutrophils, CRP, INR, aPTT, D-dimer levels compared to ward patients. PAF-AH activity was significantly increased in ICU patients compared to the control group (p < .05). A positive correlation was found between PAF-AH and D-Dimer in the ICU group.
Conclusion: We found increased PAF-AH activity in patients with Covid-19. It’s important to spot the PAF-AH activity in cardiovascular events that develop due to coagulation problems, which are likely to be seen on these patients in the future.
{"title":"Platelet Activating Factor Acetylhydrolase (PAF-AH) activity : could it have a role on coagulation in covid-19 patients?","authors":"Tülin BAYRAK, Gülsen ŞENER, Emel SAĞLAM GÖKMEN, Ahmet BAYRAK","doi":"10.33808/clinexphealthsci.1033882","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1033882","url":null,"abstract":"Objective: Abnormal immune inflammatory response and cytokine storm play an important role on the aspect of increasing mortality in Covid-19. We aimed to investigate whether the Platelet Activating Factor Acetylhydrolase activity (PAF-AH) and hematological parameters have prognostic and predictive value in determining the disease severity.
 Methods: A total of 84 Covid-19 patients, 52 of whom were hospitalized in the ward and 32 in the intensive care unit (ICU), and 38 control patients were included in this study. 
 Results: Lymphocyte and serum albumin levels were significantly lower (p < .001) and age, neutrophils, CRP, procalcitonin, LDH, INR, D-dimer levels were significantly higher (p < .001) in Covid-19 patients compared to the control group. ICU patients had significantly lower (p < .001) lymphocyte, albumin values and significantly higher (p < .001) age, leukocyte, neutrophils, CRP, INR, aPTT, D-dimer levels compared to ward patients. PAF-AH activity was significantly increased in ICU patients compared to the control group (p < .05). A positive correlation was found between PAF-AH and D-Dimer in the ICU group.
 Conclusion: We found increased PAF-AH activity in patients with Covid-19. It’s important to spot the PAF-AH activity in cardiovascular events that develop due to coagulation problems, which are likely to be seen on these patients in the future.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135937969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.33808/clinexphealthsci.888309
Kezban KORAŞ SÖZEN, Neziha KARABULUT
Objective: The present study was conducted to determine of the relationship between family and social support and anxiety-depression levels in liver transplant patients.
Methods: The Introductory Characteristics Determination Form, Hospital Anxiety and Depression Scale (HADS), Multidimensional Perceived Social Support Scale (MPSSS) and Perceived Family Support Scale (PFSS) were used to question the socio-demographic characteristics of the patients.
Results: When the distribution of the mean anxiety and depression scores according to their introductory characteristics of the patients was examined, it was determined that the mean score of HADS was found to be high (HAD-A=19.71±3.29, HAD-D=15.90±1.99). The mean MPSSS of the patients was found to be at moderate level as 54.56±17.40; and the mean total score of the PFSS of the patients was found to be at high level as 35.77± 7.16. It was determined that family and social support was effective in reducing the depression levels after liver transplantation.
Conclusions: It was found that family and social support was influential in reducing the depression levels after liver transplantation.
{"title":"Determination of the Relationship Between Family and Social Support and Anxiety-Depression Levels in Liver Transplant Patients","authors":"Kezban KORAŞ SÖZEN, Neziha KARABULUT","doi":"10.33808/clinexphealthsci.888309","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.888309","url":null,"abstract":"Objective: The present study was conducted to determine of the relationship between family and social support and anxiety-depression levels in liver transplant patients.
 Methods: The Introductory Characteristics Determination Form, Hospital Anxiety and Depression Scale (HADS), Multidimensional Perceived Social Support Scale (MPSSS) and Perceived Family Support Scale (PFSS) were used to question the socio-demographic characteristics of the patients.
 Results: When the distribution of the mean anxiety and depression scores according to their introductory characteristics of the patients was examined, it was determined that the mean score of HADS was found to be high (HAD-A=19.71±3.29, HAD-D=15.90±1.99). The mean MPSSS of the patients was found to be at moderate level as 54.56±17.40; and the mean total score of the PFSS of the patients was found to be at high level as 35.77± 7.16. It was determined that family and social support was effective in reducing the depression levels after liver transplantation.
 Conclusions: It was found that family and social support was influential in reducing the depression levels after liver transplantation.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135937967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-05DOI: 10.33808/clinexphealthsci.1216743
Gülay Çakir, Zeliha ŞANIVAR ABBASGHOLIZADEH, Yılmaz Umut Aslan
Objective: To evaluate the shear bond strength (SBS) of yttrium-stabilized tetragonal zirconia polycrystals bonded to titanium alloys via different surface treatment methods using four different cements. Methods: Eighty titanium and monolithic zirconia discs were prepared with computer-aided design/manufacturing (CAD/CAM) technology. All titanium discs and 40 of monolithic zirconia discs were polished by using silicon carbide paper and sandblasted with 50 μm aluminum oxide (Al2O3). Tribochemical silica coating was applied to remaining 40 monolithic zirconia discs. The monolithic zirconia discs were divided into eight groups after surface treatment (n=10). Titanium discs were cemented using conventional glass ionomer cement (GIC), resin-modified GIC, self- adhesive resin cement, and dual-cure resin cement. The SBS test was performed using a universal testing machine. The failure patterns were examined by using a scanning electron microscope (SEM). Data were statistically analyzed with one-way analysis of variance (ANOVA), two-way ANOVA and Tukey’s test (α
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Pub Date : 2023-08-14DOI: 10.33808/clinexphealthsci.1171072
Sevda Emi̇r, S. Gözüm
Objective: The migration movement from Russia to Antalya is predominantly women and children. The aim of this research was to compare the healthy lifestyle behaviors of Russian women residing in Antalya and their primary school children with their Turkish peers. Methods: This is descriptive comparative research. The study with a purposive sample method included students in grades 1-8 of one private Russian primary school and their mothers, as well as students from three private Turkish schools in the same region and their mothers to ensure similarity. 122 Turkish and 76 Russian mothers and child couples participated in the study. Russian women and Turkish peers completed Healthy Lifestyle Behaviors Scale and the International Physical Activity Questionnaire. The Nutritional Behavior Scale and the Child Physical Activity Questionnaire (CPAQ) were fulfilled by children. Results: Russian women were better healthy lifestyle behaviors than Turkish peers in health responsibility (z=-3,91; p
目的：从俄罗斯移民到安塔利亚的主要是妇女和儿童。本研究旨在比较居住在安塔利亚的俄罗斯妇女及其小学生与土耳其同龄人的健康生活方式行为。 研究方法：这是一项描述性比较研究。研究采用目的性抽样方法，包括一所俄罗斯私立小学 1-8 年级的学生及其母亲，以及同一地区三所土耳其私立学校的学生及其母亲，以确保相似性。122 对土耳其母亲和 76 对俄罗斯母亲及其子女参加了研究。俄罗斯妇女和土耳其同龄人填写了健康生活方式行为量表和国际体育活动问卷。儿童填写了营养行为量表和儿童体育活动问卷（CPAQ）。 结果显示在健康责任方面，俄罗斯妇女的健康生活方式行为优于土耳其同龄人（z=-3,91; p
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