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The effect of different implant-abutment types and heights on screw loosening in cases with increased crown height space 在牙冠高度空间增大的情况下,不同的种植体基台类型和高度对螺钉松动的影响。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.894
Amirreza Hendi, Sobhan Mirzaee, Mehran Falahchai

Objectives

The stability of the abutment screw is pivotal for successful implant-supported restorations, yet screw loosening remains a common complication, leading to compromised function and potential implant failure. This study aims to evaluate the effect of different implant-abutment types and heights on screw loosening in cases with increased crown height space (CHS).

Materials and Methods

In this in vitro study, a total of 64 abutments in eight distinct groups based on their type and height were evaluated. These groups included stock, cast, and milled abutments with heights of 4 mm (groups S4, C4, and M4), 7 mm (groups S7, C7, and M7), and 10 mm (groups C10 and M10). Removal torque loss (RTL) was assessed both before and after subjecting the abutments to dynamic cyclic loading. Additionally, the differences between initial RTL and RTL following cyclic loading were analyzed for each group (p < .05).

Results

The C10 group demonstrated the highest RTL, whereas the S4 group exhibited the lowest initial RTL percentage (p < .05). Furthermore, the study established significant variations in RTL percentages and the discrepancies between initial and postcyclic loading RTL across different abutment groups (p < .05). Additionally, both abutment types and heights were found to significantly influence the RTL percentage (p < .05).

Conclusion

The type and height of the implant abutment affected screw loosening, and in an increased CHS of 12 mm, using a stock abutment with a postheight of 4 mm can be effective in minimizing screw loosening.

目的:基台螺丝的稳定性是种植体支持修复成功的关键,但螺丝松动仍然是常见的并发症,会导致功能受损和潜在的种植体失败。本研究旨在评估在牙冠高度空间(CHS)增大的情况下,不同种植体基台类型和高度对螺丝松动的影响:在这项体外研究中,根据基台的类型和高度,共对 8 个不同组别中的 64 个基台进行了评估。这些组包括高度为 4 毫米(S4、C4 和 M4 组)、7 毫米(S7、C7 和 M7 组)和 10 毫米(C10 和 M10 组)的库存基台、铸造基台和研磨基台。在基台承受动态循环加载之前和之后,都对移除扭矩损失(RTL)进行了评估。此外,还分析了各组初始 RTL 与循环加载后 RTL 之间的差异(p 结果:C10 组的 RTL 最高,而 S4 组的初始 RTL 百分比最低(p 结论:C10 组和 S4 组的初始 RTL 百分比最高,而 S4 组的初始 RTL 百分比最低:种植体基台的类型和高度对螺钉松动有影响,在 CHS 增加到 12 mm 的情况下,使用后高度为 4 mm 的库存基台可以有效地减少螺钉松动。
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引用次数: 0
Prevalence of Histopathologic Types of Gingival Lesions in the Iranian Population: A 22-Year Retrospective Study 伊朗人口牙龈病变组织病理学类型的流行率:一项为期 22 年的回顾性研究
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.911
Nafiseh Shamloo, Mostafa Alam, Armin Khaleghi

Objectives

Gingiva is one of the supporting tissues around the teeth that can be affected by various neoplastic or nonneoplastic lesions. Previous studies have examined several types of gingival lesions, but the lack of a standardized classification system has hindered meaningful comparisons. Additionally, many studies focused primarily on reactive lesions. Our study aims to contribute to the understanding of gingival lesions by investigating their prevalence across age groups, genders, sites, and by their clinical presentation. This research could lead to improved diagnostic accuracy and treatment strategies.

Materials and Methods

This retrospective study explores the prevalence of gingival lesions based on biopsies during a 22-year span. The patient's demographic details, including age, gender, and lesion's clinical presentation were systematically collected. These lesions were categorized into six groups. Descriptive statistics, χ2 test of independence, and one-way ANOVA were used for data analysis.

Results

Among the 7668 biopsied lesions, 684 (8.9%) lesions were located in the gingiva, with a greater occurrence in women (63.5%). Soft tissue tumors represented the most prevalent group in the gingival lesions (72.1%), and peripheral giant cell granuloma (PGCG) was the most frequent lesion (21.2%), followed by, pyogenic granuloma (19.3%), peripheral ossifying fibroma (17.8%) and focal fibrous hyperplasia (7.6%); all of which predominantly affected women, with mean ages falling in the fourth decade of life. Squamous cell carcinoma was recognized as the most common malignancy.

Conclusion

In this study, PGCG was found to be the most common lesion in the gingiva in Iranian population. Further analysis using a unanimous categorization is required to confirm these results.

目的:牙龈是牙齿周围的支持组织之一,可能受到各种肿瘤性或非肿瘤性病变的影响。以往的研究已对几种类型的牙龈病变进行了研究,但由于缺乏标准化的分类系统,因此无法进行有意义的比较。此外,许多研究主要关注反应性病变。我们的研究旨在通过调查不同年龄组、不同性别、不同部位以及不同临床表现的牙龈病变发生率,加深对牙龈病变的了解。这项研究可提高诊断准确性并改进治疗策略:这项回顾性研究根据 22 年间的活组织切片探讨了牙龈病变的患病率。研究系统地收集了患者的人口统计学资料,包括年龄、性别和病变的临床表现。这些病变被分为六组。数据分析采用了描述性统计、χ2独立性检验和单因素方差分析:结果:在 7668 例活检病变中,有 684 例(8.9%)位于牙龈,其中女性病例较多(63.5%)。软组织肿瘤是牙龈病变中最常见的一类(72.1%),外周巨细胞肉芽肿(PGCG)是最常见的病变(21.2%),其次是化脓性肉芽肿(19.3%)、外周骨化性纤维瘤(17.8%)和局灶性纤维增生症(7.6%);所有这些病变都以女性为主,平均年龄在 40 岁左右。鳞状细胞癌是最常见的恶性肿瘤:本研究发现,PGCG 是伊朗人群中最常见的牙龈病变。需要使用一致的分类方法进行进一步分析,以确认这些结果。
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引用次数: 0
Investigating the effect of depression on clinical symptoms of temporomandibular disorder in young stressful men 研究抑郁症对年轻压力男性颞下颌关节紊乱临床症状的影响。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.909
Maryam Sadrzadeh Afshar, Behzad Salari, Sina Varasteh Nejad

Objectives

The objective of this study was to investigate the relationship of the depression level with temporomandibular disorders (TMDs) in young conscripts as a population with chronic stresses.

Material and Methods

A total number of 144 male conscripts with chronic stress and different levels of depression were assigned to four groups according to the Beck's Depression Inventory (BDI). The control group consisted of age-matched male conscripts without chronic stress. The diagnosis of TMD was made according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Data were analyzed using Mann–Whitney and chi-square tests.

Results

The participants with severe depression were significantly more susceptible to have TMD (p = .001) followed by the moderate depression, borderline clinical depression, mild mood disturbance, and control groups. The TMD diagnoses were more prevalent within depression groups compared with the control population (p = .01).

Conclusions

The level of depression is directly associated with the presence of TMD in young men with chronic stress.

研究目的本研究的目的是调查作为长期压力人群的应征青年的抑郁程度与颞下颌关节紊乱症(TMDs)之间的关系:根据贝克抑郁量表(BDI)将患有慢性压力和不同抑郁程度的 144 名男性应征者分为四组。对照组由年龄匹配、无慢性压力的男性应征者组成。TMD 的诊断依据是颞下颌关节紊乱诊断标准(DC/TMD)。数据采用曼-惠特尼检验和卡方检验进行分析:结果:重度抑郁症患者更易患 TMD(p = .001),其次是中度抑郁症组、边缘临床抑郁症组、轻度情绪障碍组和对照组。与对照组相比,抑郁组的 TMD 诊断率更高(p = .01):结论:抑郁程度与患有慢性压力的年轻男性是否患有 TMD 直接相关。
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引用次数: 0
Diagnostic value of aMMP-8 and azurocidin in peri-implant sulcular fluid as biomarkers of peri-implant health or disease 作为种植体周围健康或疾病的生物标志物,种植体周围龈沟液中的 aMMP-8 和 azurocidin 具有诊断价值。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-09 DOI: 10.1002/cre2.883
Vithleem Xanthopoulou, Ismo T. Räisänen, Timo Sorsa, Dimitrios Tortopidis, Dimitra Sakellari

Objective

The objective of this study was to investigate the effectiveness of testing for active matrix metalloproteinase-8 (aMMP-8) by a quantitative point-of-care (PoC), chairside lateral flow immunotest and azurocidin, in the peri-implant sulcular fluid (PISF), as biomarkers for the presence or absence of peri-implant diseases.

Background

Current research indicates that proinflammatory cytokines and extracellular matrix-degrading enzymes may be of value to diagnose and predict peri-implant disease initiation and progression, but more data are needed.

Methods

Eighty patients with implants were recruited. PISF samples were collected and quantitatively analyzed for aMMP-8 (chairside) and azurocidin with ELISA. Radiographic assessments and clinical indices (probing depth, probing attachment level, bleeding on probing, and plaque) were recorded after sampling. Kruskal-Wallis test and pairwise post hoc Dunn-Bonferroni test were used to relate aMMP-8 levels and azurocidin levels to clinical parameters. The diagnostic ability of aMMP-8 (ng/mL) and azurocidin was analyzed by receiver operator curve analysis. Area under the curve (AUC) was calculated and the Spearman's rho, and the coefficient of determination (R2) were used to calculate the correlations between aMMP-8, azurocidin, and periodontal parameters.

Results

Statistically significant differences were observed for aMMP-8 levels but not for azurocidin between healthy implants, implants with mucositis, and those with peri-implantitis (13.65 ± 7.18, 32.33 ± 21.20, and 73.07 ± 43.93 ng/mL, respectively), (Kruskall–Wallis test p < .05). The aMMP-8 test with a threshold of 20 ng/mL has a sensitivity of 71.7% and a specificity of 77.8% to identify peri-implantitis and healthy implants, respectively. AUC was found to be 0.814, and the accuracy of the method reaches 73.8%. Above a cutoff value of 33.7 ng/mL of aMMP-8, the accuracy of the test to detect peri-implantitis reaches 77.5% in relation to 62.5% of BoP from the same site.

Conclusion

Taken collectively, present data indicate that the aMMP-8 PoC lateral flow immunotest can be a beneficial, adjunctive diagnostic quantitative tool for real-time screening for peri-implant diseases.

研究目的本研究的目的是探讨通过定量床旁侧流免疫测定(PoC)检测种植体周围龈沟液(PISF)中的活性基质金属蛋白酶-8(aMMP-8)和氮芥作为生物标志物检测种植体周围疾病存在与否的有效性:背景:目前的研究表明,促炎细胞因子和细胞外基质降解酶可能对诊断和预测种植体周围疾病的发生和发展有价值,但还需要更多的数据:方法:招募了 80 名种植体患者。收集 PISF 样本,并用 ELISA 对 aMMP-8(椅旁)和azurocidin 进行定量分析。取样后记录放射学评估和临床指标(探诊深度、探诊附着水平、探诊出血和牙菌斑)。采用 Kruskal-Wallis 检验和配对后 Dunn-Bonferroni 检验将 aMMP-8 和 Azurocidin 水平与临床指标联系起来。通过接收者运算曲线分析法分析了aMMP-8(纳克/毫升)和氮芥苷的诊断能力。计算了曲线下面积(AUC),并使用斯皮尔曼rho和判定系数(R2)计算了aMMP-8、氮芥和牙周参数之间的相关性:结果:在健康种植体、粘膜炎种植体和种植体周围炎种植体之间,aMMP-8 水平有统计学意义的差异(分别为 13.65 ± 7.18、32.33 ± 21.20 和 73.07 ± 43.93 ng/mL),而氮杂络氨酸水平无统计学意义的差异(Kruskall-Wallis 检验 p 结论:综上所述,本数据表明 aMMP-8 PoC 侧流免疫测定是一种有益的辅助诊断定量工具,可用于实时筛查种植体周围疾病。
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引用次数: 0
Un “boxing” the reality: Knowledge, attitude, and perception of orthodontists, dental practitioners, and orthodontic patients toward mouthguards' wear during contact sports—A cross-sectional study 不 "拳击 "现实:正畸医生、牙科医生和正畸患者对接触性运动中佩戴护齿的认识、态度和看法--横断面研究
IF 1.8 Q3 Dentistry Pub Date : 2024-06-04 DOI: 10.1002/cre2.904
Shailaja Raghavan, Elham S. Abu Alhaija, Yousef Nasrawi, Susan Al- Khateeb, Samer Sunna

Introduction

Mouthguards (MGs) have the potential to prevent contact sport-related dental injuries. However, varying perceptions of their effectiveness persist, influencing recommendations by dental professionals.

Aim

To assess the attitudes, knowledge, and perceptions of orthodontists, other dental practitioners (general dentists and other dental specialists), and orthodontic patients involved in contact sports regarding the use of MGs.

Methodology

A cross-sectional survey was designed to collect information from dental clinicians (orthodontists and other dental practitioners) and their orthodontic patients about using MGs during sports participation. A convenience sampling technique was used to recruit the participants for an online survey. A total of 107 (32 males/75 females) dental clinicians and 147 (75 males/72 females) orthodontic patients (mean age 17.5 ± 5.84 years) participated in the study. Pre-validated questionnaires, specifically designed for dental clinicians and orthodontic patients, were used. Data were analyzed using SPSS software (version 28.0; SPSS).

Results

Nearly 50% of dental clinicians have recently recommended MGs to their patients in their clinical practice out of which 59% preferred the stock type; 33% of dental clinicians enquired their patients about involvement in contact sports during initial visits. The majority of orthodontic patients acquired knowledge about MGs through the Internet. More than half of orthodontic patients expressed unwillingness to pay for MGs, and 89% of orthodontic patients found using MGs during contact sports uncomfortable.

Conclusion

The findings provide valuable insights into the practices and attitudes of dental clinicians and orthodontic patients regarding MGs, their recommendations, and the comfort levels associated with using them during contact sports.

导言 护齿器(MGs)具有预防与接触性运动相关的牙科损伤的潜力。然而,人们对其有效性的不同认识一直影响着牙科专业人员的建议。 目的 评估正畸医师、其他牙科从业人员(普通牙医和其他牙科专家)以及参与接触性运动的正畸患者对使用护齿的态度、知识和看法。 方法 设计了一项横断面调查,以收集牙科临床医生(正畸医生和其他牙科从业人员)及其正畸患者关于在参加体育运动时使用制动喷雾器的信息。调查采用方便抽样技术,招募参与者参与在线调查。共有 107 名(32 名男性/75 名女性)牙科临床医师和 147 名(75 名男性/72 名女性)正畸患者(平均年龄为 17.5 ± 5.84 岁)参与了研究。研究采用了专门为牙科临床医生和正畸患者设计的、经过预先验证的问卷。数据使用 SPSS 软件(28.0 版;SPSS)进行分析。 结果 近 50%的牙科临床医生最近在临床实践中向患者推荐了MGs,其中59%的人更喜欢股票型MGs;33%的牙科临床医生在初次就诊时询问了患者参与接触性运动的情况。大多数正畸患者都是通过互联网获得有关制粒剂的知识的。超过半数的正畸患者表示不愿意支付制粒剂的费用,89%的正畸患者认为在接触性运动中使用制粒剂不舒服。 结论 这些研究结果为了解牙科临床医生和正畸患者对制导喷雾剂的做法和态度、对制导喷雾剂的建议以及在接触性运动中使用制导喷雾剂的舒适度提供了宝贵的见解。
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引用次数: 0
Comparative assessment of flexural strength of monolithic zirconia with different thicknesses and two sintering techniques 不同厚度和两种烧结技术的整体氧化锆抗弯强度比较评估
IF 1.8 Q3 Dentistry Pub Date : 2024-05-31 DOI: 10.1002/cre2.856
Nilofar Karbasian, Amirhossein Fathi, Pirooz Givehchian, Saeed Nosouhian, Mohammad Jamshidian, Farhad Almassi, Ali Fazeli

Objectives

This study aimed to compare the flexural strength of monolithic zirconia with different thicknesses and two sintering techniques.

Materials and Methods

This in vitro, experimental study was conducted on 28 monolithic zirconia discs with 10 mm diameter and 0.5 (n = 14) and 1.2 mm (n = 14) thickness. Each group was divided into two subgroups (n = 7) for fast (60 min) and conventional (120 min) sintering at 1450°C. After sintering, the specimens were thermocycled and their flexural strength was measured by piston-on-3-balls technique in a universal testing machine (0.5 mm/min, 1.2 mm pin diameter). Data were analyzed by the Weibull test, one-way analysis of variance, and Tukey's test (α = .05).

Results

The flexural strength of specimens with 1.2 mm thickness was significantly higher than that of specimens with 0.5 mm thickness (p < .05). The flexural strength of 1.2 mm/120-min group was slightly, but not significantly, higher than that of 1.2 mm/60-min group (p > .05). The flexural strength of 0.5 mm/120-min group was slightly, but not significantly, higher than that of 0.5 mm/60-min group (p > .05).

Conclusion

The increase in thickness of monolithic zirconia increases its flexural strength; however, increasing the sintering time appears to have no significant effect on the flexural strength of monolithic zirconia.

研究目的本研究旨在比较不同厚度和两种烧结技术的整体氧化锆的抗弯强度:这项体外实验研究的对象是 28 个直径为 10 毫米、厚度为 0.5 毫米(n = 14)和 1.2 毫米(n = 14)的整体氧化锆盘。每组分为两个子组(n = 7),分别在 1450°C 下进行快速(60 分钟)和传统(120 分钟)烧结。烧结后,对试样进行热循环,并在万能试验机(0.5 毫米/分钟,针直径 1.2 毫米)上采用活塞对 3 球技术测量其抗弯强度。数据分析采用 Weibull 检验、单因素方差分析和 Tukey 检验(α = .05):结果:厚度为 1.2 毫米的试样的抗弯强度明显高于厚度为 0.5 毫米的试样(p .05)。0.5 毫米/120 分钟组的抗折强度略高于 0.5 毫米/60 分钟组,但不明显(p > .05):结论:增加整体氧化锆的厚度可提高其抗弯强度;但增加烧结时间似乎对整体氧化锆的抗弯强度没有明显影响。
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引用次数: 0
The relationship between oral frailty and oral dysbiosis among hospitalized patients aged older than 50 years 50 岁以上住院病人口腔虚弱与口腔菌群失调之间的关系。
IF 1.8 Q3 Dentistry Pub Date : 2024-05-30 DOI: 10.1002/cre2.890
Yen-Chin Chen, En-Ni Ku, Pei-Fang Tsai, Che-Wei Lin, Nai-Ying Ko, Shun-Te Huang, Jiun-Ling Wang, Yi-Ching Yang

Objective

This study aimed to clarify the relationship between oral frailty and oral dysbiosis among hospitalized patients aged ≥ 50 years.

Methods

A prospective observational study was conducted. Number of teeth, masticatory ability, articulatory oral motor skill, tongue pressure, swallowing pressure, and choking were used to assess oral frailty. Saliva samples were collected from the oral cavity for bacterial culture.

Results

A total 103 in patients enrolled and 53.4% suffered from oral frailty. Oral frailty was found to have a 3.07-fold correlation with the presence of Enterobacterales in the oral cavity (p = 0.037), especially in poor articulatory oral motor skill, which showed at greater risk of Enterobacterales isolated from the oral cavity by 5.58-fold (p = 0.01).

Conclusion

Half of hospitalized patients was found to have oral frailty that was related to more Enterobacterales in the oral cavity. This evidence suggests that the enhancement of articulatory oral motor skills may serve as a potential strategy for mitigating the presence of Enterobacterales within the oral cavity.

研究目的本研究旨在阐明年龄≥50 岁的住院患者口腔虚弱与口腔菌群失调之间的关系:方法:进行前瞻性观察研究。采用牙齿数量、咀嚼能力、发音口腔运动技能、舌压、吞咽压力和呛咳来评估口腔虚弱程度。从口腔采集唾液样本进行细菌培养:结果:共有 103 名患者入选,其中 53.4% 患有口腔虚弱症。发现口腔虚弱与口腔中肠杆菌的存在有 3.07 倍的相关性(p = 0.037),尤其是发音口腔运动技能差的患者,从口腔中分离出肠杆菌的风险更高,达到 5.58 倍(p = 0.01):结论:半数住院病人的口腔功能虚弱与口腔中更多的肠杆菌有关。这些证据表明,提高口腔运动技能可能是减少口腔中肠杆菌的潜在策略。
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引用次数: 0
Assessing the suitability of fused deposition modeling to produce acrylic removable denture bases 评估熔融沉积模型是否适用于制作丙烯酸活动义齿基托。
IF 1.8 Q3 Dentistry Pub Date : 2024-05-27 DOI: 10.1002/cre2.880
Khalid K. Alanazi, Duncan Wood, Joanna Shepherd, Christopher W. Stokes, Ilida Ortega Asencio

Objective

To study the feasibility of using poly methyl methacrylate (PMMA) filament and fused deposition modeling (FDM) to manufacture denture bases via the development of a study that considers both conventional and additive-based manufacturing techniques.

Materials and Methods

Five sample groups were compared: heat and cold cured acrylic resins, CAD/CAM milled PMMA, 3D-printed PMMA (via FDM), and 3D-printed methacrylate resin (via stereolithography, SLA). All groups were subjected to mechanical testing (flexural strength, impact strength, and hardness), water sorption and solubility tests, a tooth bonding test, microbiological assessment, and accuracy of fit measurements. The performance of sample groups was referred to ISO 20795-1 and ISO/TS 19736. The data was analyzed using one-way ANOVA.

Results

Samples manufactured using FDM performed within ISO specifications for mechanical testing, water sorption, and solubility tests. However, the FDM group failed to achieve the ISO requirements for the tooth bonding test. FDM samples presented a rough surface finish which could ultimately encourage an undesirable high level of microbial adhesion. For accuracy of fit, FDM samples showed a lower degree of accuracy than existing materials.

Conclusions

Although FDM samples were a cost-effective option and were able to be quickly manufactured in a reproducible manner, the results demonstrated that current recommended testing regimes for conventionally manufactured denture-based polymers are not directly applicable to additive-manufactured denture base polymers. Therefore, new standards should be developed to ensure the correct implementation of additive manufacturing techniques within denture-based fabrication workflow.

目的:研究使用聚甲基丙烯酸甲酯(PMMA)长丝和熔融沉积建模(FDM)制造义齿基托的可行性,同时考虑传统制造技术和增材制造技术:比较了五组样品:热固化和冷固化丙烯酸树脂、CAD/CAM 铣削 PMMA、3D 打印 PMMA(通过 FDM)和 3D 打印甲基丙烯酸酯树脂(通过立体光刻,SLA)。所有样品组都接受了机械测试(抗弯强度、冲击强度和硬度)、吸水性和溶解性测试、牙齿粘合测试、微生物评估和配合精度测量。样品组的性能参照了 ISO 20795-1 和 ISO/TS 19736 标准。数据采用单因素方差分析:结果:使用 FDM 制造的样品在机械测试、吸水性和溶解性测试中均符合 ISO 规范。但是,FDM 组在牙齿粘合测试中未能达到 ISO 的要求。FDM 制成的样品表面粗糙,最终可能会助长微生物的大量附着。在贴合精度方面,FDM 样品的精度低于现有材料:尽管 FDM 样品是一种具有成本效益的选择,而且能够以可重复的方式快速制造,但结果表明,目前针对传统制造的义齿基底聚合物所推荐的测试制度并不能直接适用于添加剂制造的义齿基底聚合物。因此,应制定新的标准,以确保在义齿基托制造工作流程中正确使用添加剂制造技术。
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引用次数: 0
Frequency of apical periodontitis in root-filled teeth restored with post and core: A 5-year retrospective study 使用桩核修复根充牙的根尖牙周炎发病率:一项为期 5 年的回顾性研究。
IF 1.8 Q3 Dentistry Pub Date : 2024-05-26 DOI: 10.1002/cre2.881
Louise Johansson, Jakob Jonsson Sjögren, Anders Wirén, Alf Eliasson, Fredrik Frisk

Background

In conjunction with post placement in root-filled teeth with periapical healthy conditions, root canal retreatment may be performed to improve the seal of the root canal. Whether root canal retreatment for technical reasons (retreatments in teeth without apical periodontitis (AP)) results in lower frequency of AP is unknown.

Objective

To examine whether there is a difference in frequency of AP between roots with root canals retreated for technical reasons, and roots with root canals not retreated before post placement, with a minimum follow-up of 5 years. Also, to examine changes in root filling quality following root canal retreatment for technical reasons.

Methods

This retrospective study included radiographs of 441 root-filled roots without periapical radiolucencies at baseline, scheduled for post and core treatment. Follow-up data for a minimum of 5 years were available for 305 roots (loss to follow-up 30.8%), 46 of which were retreated for technical reasons. Two calibrated observers assessed root filling sealing quality and length, respectively, and periapical status according to the Periapical Index. The main outcome of the study, AP, was used as the dependent variable and all analyses were performed at root level.

Results

The overall frequency of AP at follow-up was 13.8%. The difference in frequency of AP between retreated (4.3%) and nonretreated (15.4%) root canals was not statistically significant, p = .061. Analyses including only roots with preoperatively inadequate root filling quality showed a statistically significant difference (p = .017) between the two treatment groups (2.4% vs. 22.9%).

Conclusions

Root canal retreatment for technical reasons before post and core placement significantly reduces the frequency of AP in roots with inadequate root filling quality.

背景:在根尖周健康的根充盈牙齿上放置根管柱的同时,可以进行根管再治疗以改善根管的密封性。由于技术原因进行根管再治疗(在没有根尖牙周炎(AP)的牙齿上进行根管再治疗)是否会降低 AP 的发生频率,目前尚不清楚:目的:在至少 5 年的随访中,研究因技术原因进行根管再治疗的牙根与在植入支架前未进行根管再治疗的牙根之间发生 AP 的频率是否存在差异。同时,研究因技术原因进行根管再治疗后根管充填质量的变化:这项回顾性研究包括对 441 个基线时无根尖周放射状突起、计划进行根管治疗和核心治疗的根充根进行放射摄影。对 305 根牙根进行了至少 5 年的随访(随访损失率为 30.8%),其中 46 根因技术原因进行了根管治疗。两名经过校准的观察员分别评估了牙根充填密封的质量和长度,并根据根尖周指数评估了根尖周状况。研究的主要结果 AP 为因变量,所有分析均在牙根水平上进行:随访中出现 AP 的总频率为 13.8%。经修复的根管(4.3%)和未经修复的根管(15.4%)之间的 AP 频率差异无统计学意义,P = 0.061。仅对术前根充质量不合格的根进行分析,结果显示两组根管治疗之间的差异有统计学意义(p = .017)(2.4% 对 22.9%):结论:在桩核置入前因技术原因进行根管再治疗可显著降低根充质量不合格的牙根发生 AP 的频率。
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引用次数: 0
Green synthesis of silver nanoparticles and evaluation of their effects on the Porphyromonas gingivalis bacterial biofilm formation 银纳米粒子的绿色合成及其对牙龈卟啉单胞菌生物膜形成影响的评估。
IF 1.8 Q3 Dentistry Pub Date : 2024-05-26 DOI: 10.1002/cre2.887
Morad Hedayatipanah, Leila Gholami, Abbas Farmany, Mohammad Yusef Alikhani, Amirarsalan Hooshyarfard, Fahime Sadat Hashemiyan

Objective

This study aimed to evaluate the impact of silver nanoparticles (AgNPs) synthesized from propolis on the formation of Porphyromonas gingivalis biofilms.

Material and Methods

AgNPs were synthesized from propolis, and their inhibitory effect on P. gingivalis biofilm formation was assessed. Different concentrations of AgNPs (0.1%, 0.3%, and 0.5%) were tested to determine the dose-dependent antibacterial activity.

Results

The results of this study indicated that AgNPs exhibited an inhibitory effect on P. gingivalis biofilm formation. The antibacterial activity of AgNPs was dose-dependent, with concentrations of 0.1%, 0.3%, and 0.5% showing effectiveness. Notably, the concentration of 0.5% demonstrated the most significant anti-biofilm formation activity.

Conclusion

The results of this study suggest that AgNPs synthesized from propolis have potential as an effective option for enhancing periodontal treatment outcomes. The inhibitory effect of AgNPs on P. gingivalis biofilm formation highlights their potential as alternative antimicrobial agents in the management of periodontal diseases.

研究目的本研究旨在评估由蜂胶合成的银纳米粒子(AgNPs)对牙龈卟啉单胞菌生物膜形成的影响:从蜂胶中合成 AgNPs,并评估其对牙龈卟啉单胞菌生物膜形成的抑制作用。测试了不同浓度的 AgNPs(0.1%、0.3% 和 0.5%),以确定其抗菌活性的剂量依赖性:研究结果表明,AgNPs 对牙龈脓胞生物膜的形成具有抑制作用。AgNPs 的抗菌活性呈剂量依赖性,浓度为 0.1%、0.3% 和 0.5% 时均有效。值得注意的是,0.5% 的浓度具有最显著的抗生物膜形成活性:本研究结果表明,由蜂胶合成的 AgNPs 有潜力成为提高牙周治疗效果的有效选择。AgNPs对牙龈脓胞生物膜形成的抑制作用凸显了其作为替代抗菌剂治疗牙周疾病的潜力。
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引用次数: 0
期刊
Clinical and Experimental Dental Research
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