Clinical and Experimental Dental Research最新文献_第2页

Impact of Dental Anxiety on the Dental Health Status of Nepali Adult Patients 牙科焦虑症对尼泊尔成年患者牙齿健康状况的影响。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-11 DOI: 10.1002/cre2.70034

Tanuja Singh, Tika R. Ghimire, Manoj Dhungana

Background

Patients with high dental anxiety are found to visit dental offices less frequently and have a higher number of severely diseased teeth so they are at a greater need for intensive oral care and rehabilitation.

Objectives

The aim of this study was to assess the prevalence of dental anxiety and its impact on the dental status of Nepali adult patients.

Material and Methods

A semi-structured questionnaire of the Modified Dental Anxiety Scale (MDAS) in the Nepali version was used for data collection. The data analysis was done using Statistical Package for Social Sciences (SPSS IBM, Chicago, IL, USA, version 24). Variables were calculated as frequency and percentage, while the comparisons of different factors were done using the ANOVA and t-test. A difference with p < 0.05 was considered statistically significant.

Results

The study population consisted of 446 subjects, among them 205 were male (45.96%), 241 were female (54.04%), 357 (80.04%) were married, and 222 (49.78%) were employed. The mean age of the patients was 41.24 years (ranging between 18 and 79 years). Only 41 subjects (9.19%) showed high dental anxiety (MDAS ≥ 19). The mean MDAS for the total study population was 10.81. The highest mean MDAS was seen in the age group 30–39 (11.78) and the lowest mean MDAS was seen in the age group 40–49 (9.64). While comparing dental anxiety among genders, dental anxiety was higher in females (mean MDAS = 11.78) compared to males (mean MDAS = 9.67). Patients having high dental anxiety had a significantly higher number of decayed teeth (p-value = 0.001, t-test).

Conclusion

Oral health and dental status both are negatively affected by dental anxiety. It interferes with dental attendance, service delivery, prevention of dental diseases, and early diagnosis. Thus, dental practitioners have a major role to play in the management of dental anxiety.

背景：高度牙科焦虑的患者到牙科诊所就诊的频率较低，严重病变牙齿的数量较多，因此他们更需要强化口腔护理和康复：本研究旨在评估牙科焦虑症的普遍程度及其对尼泊尔成年患者牙齿状况的影响：采用尼泊尔语版的改良牙科焦虑量表（MDAS）半结构式问卷进行数据收集。数据分析采用社会科学统计软件包（SPSS IBM，美国伊利诺斯州芝加哥，第 24 版）。变量以频率和百分比计算，不同因素之间的比较采用方差分析和 t 检验。结果与 p 存在差异：研究对象共 446 人，其中男性 205 人（45.96%），女性 241 人（54.04%），已婚 357 人（80.04%），在职 222 人（49.78%）。患者的平均年龄为 41.24 岁（18 至 79 岁不等）。只有 41 名受试者（9.19%）表现出高度牙科焦虑（MDAS ≥ 19）。研究总人数的平均 MDAS 为 10.81。30-39 岁年龄组的平均 MDAS 值最高（11.78），40-49 岁年龄组的平均 MDAS 值最低（9.64）。在比较不同性别的牙科焦虑时，女性的牙科焦虑（平均 MDAS = 11.78）高于男性（平均 MDAS = 9.67）。高度牙齿焦虑的患者蛀牙数量明显较多（p 值 = 0.001，t 检验）：结论：口腔健康和牙齿状况都会受到牙科焦虑的负面影响。结论：口腔健康和牙齿状况都会受到牙科焦虑的负面影响，牙科焦虑会影响牙科就诊、服务提供、牙科疾病预防和早期诊断。因此，牙科医生在牙科焦虑症的管理中扮演着重要角色。

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引用次数: 0

Impact of the COVID-19 Pandemic on Oral Health Behaviors Among Children in Iran COVID-19 大流行对伊朗儿童口腔健康行为的影响。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-11 DOI: 10.1002/cre2.70010

Mahtab Memarpour, Faranak Razmjouei, Fatemesadat Fayazi, Azade Rafiee, Mehrdad Vossoughi

Objectives

Parents are responsible for their children's oral health. This study evaluated parents' knowledge, attitudes, and performance on their children's oral health before and after an educational intervention and the impact of COVID-19 on these variables.

Material and Methods

This quasi-experimental study included 227 children aged 6–8 years who were referred to 11 Shiraz medical centers from July to December 2021. Data were collected from questionnaires and interviews. After completing the questionnaire, oral health education was provided immediately and then monthly thereafter using dental models and pamphlets. After 3 months, a questionnaire assessed the education's effectiveness. Data were analyzed using independent t-tests, one-way analysis of variance (ANOVA), paired t-tests, and Pearson's correlation.

Results

A total of 163 participants (71.80%) completed all phases, including the second questionnaire. Participants showed moderate knowledge (77.30%), attitude (89.00%), and performance (80.40%). Neither knowledge nor attitude before the intervention had a significant association with demographic characteristics. Parents' education, number of children, and maternal employment were significantly associated with performance (p = 0.002, p = 0.040, p < 0.001, respectively). The intervention significantly enhanced these variables (p < 0.001). In terms of COVID-19, 72.40% of participants expressed good knowledge about transmission, 52.80% showed moderate concern, and 54% had poor performance. Parental knowledge, attitude, and performance changed significantly following the intervention (p = 0.030, p < 0.001, p < 0.001, respectively).

Conclusions

Educational intervention significantly improved parents' knowledge, attitudes, and performance toward children's oral health. Because of the poor performance of parents during the COVID-19 pandemic, we recommend the implementation of continuing education and preventive oral health programs.

目标：父母对子女的口腔健康负有责任。本研究评估了教育干预前后家长对子女口腔健康的知识、态度和表现，以及 COVID-19 对这些变量的影响：这项准实验研究包括 2021 年 7 月至 12 月期间转诊至设拉子 11 家医疗中心的 227 名 6-8 岁儿童。数据通过问卷和访谈收集。填写问卷后，立即进行口腔健康教育，之后每月使用牙科模型和小册子进行口腔健康教育。3 个月后，对教育效果进行问卷评估。数据分析采用独立 t 检验、单因素方差分析（ANOVA）、配对 t 检验和皮尔逊相关分析：共有 163 名参与者（71.80%）完成了包括第二次问卷调查在内的所有阶段。参与者的知识（77.30%）、态度（89.00%）和表现（80.40%）均处于中等水平。干预前的知识和态度与人口统计学特征均无明显关联。父母的教育程度、子女数量和母亲的就业情况与表现有明显的相关性（P = 0.002，P = 0.040，P 结论：父母的教育程度、子女数量和母亲的就业情况与表现有明显的相关性（P = 0.002，P = 0.040）：教育干预明显改善了家长对儿童口腔健康的认识、态度和表现。由于在 COVID-19 大流行期间家长的表现不佳，我们建议实施持续教育和预防性口腔健康计划。

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引用次数: 0

Prosthetic Soft Tissue Management in Esthetic Implant Restorations, Part I: Presurgical Planning, Implant Placement, and Restoration Timing. A Narrative Review 美容种植修复中的修复软组织管理，第一部分：手术前规划、种植体植入和修复时机。叙述性综述。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-08 DOI: 10.1002/cre2.900

Faezeh Atri, Kimia Nokar

Objectives

This two-part review article delineates various techniques to enhance esthetic outcomes in anterior implant treatments. Part I concentrates on presurgical measures, case selection, implant placement, and restoration timing. Part II discusses post-surgical steps, the temporary restoration phase, the emergence profile contour, abutment types, and impression techniques.

Material and Methods

A comprehensive search was conducted using Medline/PubMed, Embase, Scopus, and the Cochrane Library. The primary keywords included were “Dental Implants,” “Dental Prosthesis, Implant-Supported,” “Esthetics, Dental,” “Dental Impression Techniques,” and “Tissue Management.”

Results

Initially, 1472 studies were identified, from which 187 were selected based on publication year and title relevance. After removing duplicates, 84 abstracts were reviewed in full text, culminating in 59 studies being thoroughly analyzed.

Conclusions

Optimal esthetics in implant restorations are attainable through meticulous treatment planning, precise surgical execution, and systematic restorative steps, ensuring predictable outcomes. Factors such as a thick gingival biotype, an intact facial bone wall, and atraumatic extraction significantly contribute to superior esthetic results. Immediate implant placement combined with immediate provisionalization provides the most predictable outcomes by supporting and maintaining soft tissue architecture. Conversely, delayed implant placement and provisionalization often require extensive manipulation of collapsed soft tissues to achieve desired esthetics.

目的：这篇评论文章由两部分组成，阐述了在前牙种植治疗中提高美学效果的各种技术。第一部分集中讨论手术前措施、病例选择、种植体植入和修复时机。第二部分讨论了手术后步骤、临时修复阶段、外形轮廓的出现、基台类型和印模技术：使用 Medline/PubMed、Embase、Scopus 和 Cochrane 图书馆进行了全面搜索。主要关键词包括 "牙科植入物"、"牙科假体、植入物支持"、"美学、牙科"、"牙科印模技术 "和 "组织管理"：初步确定了 1472 项研究，并根据发表年份和标题相关性从中筛选出 187 项。去除重复内容后，对 84 篇摘要进行了全文审阅，最终对 59 篇研究进行了深入分析：通过细致的治疗规划、精确的手术执行和系统的修复步骤，种植体修复可以达到最佳的美学效果，从而确保可预测的结果。牙龈生物型厚实、面部骨壁完整、无创伤拔牙等因素都能显著提高美学效果。即刻种植体植入与即刻临时修复相结合，通过支持和维护软组织结构来实现最可预测的效果。相反，延迟种植体植入和临时修复通常需要对塌陷的软组织进行大量操作，才能达到理想的美学效果。

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引用次数: 0

A Pilot Investigation Into the Use of Teledentistry and Artificial Intelligence to Assess Dental Erosion in Competitive Swimmers 使用远程牙科和人工智能评估竞技游泳运动员牙齿腐蚀情况的试点调查。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-07 DOI: 10.1002/cre2.70018

Jacopo Lanzetti, Federica Ferrati, Lorenzo Pavone, Federico Mussano

Objective

The aim of the study was to assess the prevalence of dental erosion in competitive swimmers using teledentistry and artificial intelligence.

Materials and Methods

An opportunistic sample of 20 competitive swimmers was recruited. The participants reported that they carried out an average of 2.40 h of training per day, 4.45 days per week. Data gathering was carried out remotely. The subjects completed a digital questionnaire and uploaded three photos of their mouth. Intraoral photographs were analyzed using the “Intact-Tooth” application to assess dental erosion. A statistical analysis was carried out to verify a possible correlation between the collected data.

Results

The average calculated Basic Erosive Wear Examination (BEWE) index was 13.95, and 11 subjects (55%) had a severe BEWE (≥ 14). More than 40% of the participants disagreed about having social issues related to tooth hypersensitivity. Considering only subjects with a severe total BEWE value, we have observed an indirect correlation between the degree of dental erosion and diet (Pearson coefficient r = −0.57), whereas a direct correlation was observed between dental erosion and age (r = 0.493) and between BEWE and weekly training hours (r = 0.217).

Conclusions

Because of their lifestyle, competitive swimmers can be considered at a higher risk of developing dental erosion. In this context, teledentistry and AI tools can be effectively used to intercept those at the highest risk and prevent the occurrence of conditions.

Summary

Dental erosion assessment in competitive swimmers using teledentistry and AI.

研究目的研究旨在利用远程齿科技术和人工智能评估竞技游泳运动员牙蚀症的患病率：研究对象为 20 名游泳运动员。据参与者称，他们平均每天进行 2.40 小时的训练，每周训练 4.45 天。数据收集以远程方式进行。受试者填写了一份数字问卷，并上传了三张口腔照片。使用 "Intact-Tooth "应用程序对口内照片进行分析，以评估牙蚀情况。为了验证收集到的数据之间可能存在的相关性，我们进行了统计分析：计算得出的基本侵蚀磨损检查（BEWE）平均指数为 13.95，11 名受试者（55%）的基本侵蚀磨损检查指数严重（≥ 14）。超过 40% 的受试者不同意存在与牙齿过敏有关的社会问题。仅考虑到总 BEWE 值严重的受试者，我们观察到牙齿腐蚀程度与饮食之间存在间接相关性（皮尔逊系数 r = -0.57），而牙齿腐蚀与年龄之间存在直接相关性（r = 0.493），BEWE 与每周训练时间之间存在直接相关性（r = 0.217）：结论：由于生活方式的原因，竞技游泳运动员患牙蚀症的风险较高。结论：由于竞技游泳运动员的生活方式，可以认为他们患牙蚀症的风险较高。在这种情况下，可以有效利用远程牙科检查和人工智能工具来拦截高风险人群，并预防牙蚀症的发生。

{"title":"A Pilot Investigation Into the Use of Teledentistry and Artificial Intelligence to Assess Dental Erosion in Competitive Swimmers","authors":"Jacopo Lanzetti, Federica Ferrati, Lorenzo Pavone, Federico Mussano","doi":"10.1002/cre2.70018","DOIUrl":"10.1002/cre2.70018","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The aim of the study was to assess the prevalence of dental erosion in competitive swimmers using teledentistry and artificial intelligence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>An opportunistic sample of 20 competitive swimmers was recruited. The participants reported that they carried out an average of 2.40 h of training per day, 4.45 days per week. Data gathering was carried out remotely. The subjects completed a digital questionnaire and uploaded three photos of their mouth. Intraoral photographs were analyzed using the “Intact-Tooth” application to assess dental erosion. A statistical analysis was carried out to verify a possible correlation between the collected data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The average calculated Basic Erosive Wear Examination (BEWE) index was 13.95, and 11 subjects (55%) had a severe BEWE (≥ 14). More than 40% of the participants disagreed about having social issues related to tooth hypersensitivity. Considering only subjects with a severe total BEWE value, we have observed an indirect correlation between the degree of dental erosion and diet (Pearson coefficient <i>r</i> = −0.57), whereas a direct correlation was observed between dental erosion and age (<i>r</i> = 0.493) and between BEWE and weekly training hours (<i>r</i> = 0.217).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Because of their lifestyle, competitive swimmers can be considered at a higher risk of developing dental erosion. In this context, teledentistry and AI tools can be effectively used to intercept those at the highest risk and prevent the occurrence of conditions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Summary</h3>\u0000 \u0000 <p>Dental erosion assessment in competitive swimmers using teledentistry and AI.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anticholinergic Burden and Dry Mouth Problems Among Older Adults (≥ 50 Years) Receiving Dental Care—A Retrospective, Cross-Sectional Analysis 接受牙科治疗的老年人（≥ 50 岁）的抗胆碱能负担和口干问题--一项回顾性横断面分析。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-05 DOI: 10.1002/cre2.70009

Christoph Matthias Schoppmeier, Isabel Deeg, Michael Jochen Wicht, Anna Greta Barbe

<div> <section> <h3> Objectives</h3> <p>Anticholinergics cause dry mouth and are highly relevant for dentists, but little is known about the relationships between intake and the occurrence of subjective and objective dry mouth with age. The German anticholinergic burden score (GACB) is a novel anticholinergic score that re-evaluates medications, particularly, those with classification discrepancies.</p> </section> <section> <h3> Material and Methods</h3> <p>We retrospectively investigated the GACB in older patients receiving dental care, evaluated whether GACB is related to xerostomia and unstimulated salivary secretion, and determined the influence of increasing age (beginning at 50 years of age). The GACB score quantified cumulative anticholinergic effects: 0 for no effect, 1 for possible, 2 for moderate, and 3 for strong. Cross-sectional data in patients ≥ 50 years were collected, including xerostomia with the visual analog scale, unstimulated salivary flow rates, and the GACB scores.</p> </section> <section> <h3> Results</h3> <p>Among 172 patients (mean age 65.67 ± 9.51 years), 23.8% had a GACB score ≥ 1. A moderate negative correlation was observed between GACB and unstimulated salivary flow rates (<span></span><math> <semantics> <mrow> <mover> <mi>r</mi> <mo>̅</mo> </mover> </mrow> <annotation> $mathop{r}limits^{̅}$</annotation> </semantics></math> = −0.51). Patients with GACB ≥ 1 had fewer teeth (mean 21.76 ± 5.41) than those with GACB = 0 (24.07 ± 5.57). Moreover, unstimulated hyposalivation was observed in 61.0% with GACB ≥ 1 versus 6.8% with GACB = 0 (<i>p</i> < 0.001). Escalating chronic systemic conditions and prescribed medications were recorded with increasing age; those aged 76–80 years had the highest burden.</p> </section> <section> <h3> Conclusions</h3> <p>The GACB quickly and reliably assesses anticholinergic exposure and risks for oral health in older patients. Routine use in those aged ≥ 50 years could enable early identification of risks and initiation of preventive dental measures.</p> </section> <section> <h3> Trial Registration</h3> <p>German Registry for Clinical Trials: DRKS00032877 (https://www.germanctr.de; date of registration: 17.10.2023).</p> </section> <

目的：抗胆碱能药物会导致口干，与牙科医生密切相关，但人们对其摄入量与随着年龄增长而出现的主观和客观口干之间的关系知之甚少。德国抗胆碱能药物负担评分（GACB）是一种新型抗胆碱能药物评分方法，可重新评估药物，尤其是那些分类不一致的药物：我们对接受牙科治疗的老年患者的 GACB 进行了回顾性调查，评估了 GACB 是否与口腔干燥症和非刺激性唾液分泌有关，并确定了年龄增长（从 50 岁开始）的影响。GACB 评分量化了累积的抗胆碱能效应：0 表示无影响，1 表示可能有影响，2 表示中度影响，3 表示强烈影响。收集了年龄≥50 岁患者的横断面数据，包括口干症视觉模拟量表、非刺激性唾液流量和 GACB 评分：在 172 名患者（平均年龄为 65.67 ± 9.51 岁）中，23.8% 的患者 GACB 评分≥1。GACB 与非刺激唾液流速之间呈中度负相关（r ̅ $mathop{r}limits^{̅}$ =-0.51）。与 GACB = 0（24.07 ± 5.57）的患者相比，GACB ≥ 1 的患者的牙齿数量较少（平均 21.76 ± 5.41）。此外，61.0% 的 GACB ≥ 1 患者与 6.8% 的 GACB = 0 患者相比，出现了非刺激性唾液分泌过少（p 结论：GACB ≥ 1 患者的唾液分泌过少率低于 GACB = 0 患者：GACB 可以快速、可靠地评估老年患者的抗胆碱能暴露和口腔健康风险。在年龄≥50 岁的人群中常规使用该方法，可及早识别风险并启动牙科预防措施：试验注册：德国临床试验注册中心：DRKS00032877 (https://www.germanctr.de; 注册日期：17.10.2023)。

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引用次数: 0

Occlusal and Cephalometric Outcomes of Cleft Orthognathic Surgery: A Retrospective Cohort Study 唇裂正颌手术的咬合和头颅测量结果：回顾性队列研究

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-04 DOI: 10.1002/cre2.70019

Daniel Stonehouse-Smith, Aida N.A. Abd Rahman, Victoria Beale, Haydn Bellardie

Objectives

Aberrant facial growth in individuals affected by orofacial clefts can result in maxillary retrusion and class III malocclusion, with a proportion requiring surgical correction at cessation of growth. This study aimed to evaluate occlusal and cephalometric outcomes of combined orthodontic-orthognathic treatment.

Material and Methods

Retrospective cohort study in a United Kingdom cleft center. Participants included twenty-seven patients (20 males, 7 females) with cleft (n = 16 UCLP :7 BCLP :4 ICP) who consecutively underwent combined surgical treatment for Class III malocclusion between January 2013 and December 2017. Records were collected pre-treatment (T0), pre-surgery (T1) and at debond (T2). Models were scored using the Peer Assessment Rating (PAR) index and cephalometric radiographs were traced and analyzed. Outcomes were assessed by an independent rater.

Results

Mean age at surgery was 21.4 years (SD 4.9). Le Fort 1 advancement (mean 6.1 mm, SD 4.0) was performed in all cases. Additional procedures included mandibular setback (n = 2), cortico-cancellous bone grafting (n = 6) and genioplasty (n = 1). Mean T0 PAR score was 44.8 (SD 11.7), reducing to 3.6 (SD 2.0) at T2, indicating a mean % PAR score reduction of 91.6% (SD 4.7). Class III skeletal profiles improved from a mean T0 ANB of −2.1º (SD 2.2), to 2.8º (SD 1.6) at T2. Mean T0 overjet was −3.3 mm (SD 2.3), increasing to 2.6 mm (SD 1.3) at T2.

Conclusion

Cleft orthognathic surgery differs in complexity and approach to routine orthognathics, however, these results demonstrate that occlusal outcomes can still be comparable with non-cleft populations. Outcome data can be used for comparison with other centers providing cleft orthognathic treatment.

目的：口面裂患者面部发育异常可导致上颌后缩和III度错颌畸形，其中一部分患者在停止发育时需要进行手术矫正。本研究旨在评估正畸-正颌联合治疗的咬合和头型测量结果：在英国一家裂隙中心进行的回顾性队列研究。参与者包括二十七名患者（20 名男性，7 名女性），他们都是在 2013 年 1 月至 2017 年 12 月期间连续接受了 III 类错牙合畸形联合手术治疗的唇裂患者（n = 16 UCLP :7 BCLP :4 ICP）。收集了治疗前（T0）、手术前（T1）和脱颌时（T2）的记录。使用同行评估等级（PAR）指数对模型进行评分，并对头颅X光片进行追踪和分析。结果由一名独立评分员进行评估：手术时的平均年龄为 21.4 岁（标清 4.9）。所有病例都进行了 Le Fort 1 前移（平均 6.1 毫米，标准差 4.0）。其他手术包括下颌后移（2 例）、皮质冠状骨移植（6 例）和咬肌成形术（1 例）。T0的平均PAR评分为44.8（标准差11.7），T2时降至3.6（标准差2.0），表明平均PAR评分降低了91.6%（标准差4.7）。III 类骨骼轮廓的平均 T0 ANB 从 -2.1º (SD 2.2) 下降到 T2 时的 2.8º (SD 1.6)。T0过咬合平均值为-3.3毫米（标准差2.3），T2时增加到2.6毫米（标准差1.3）：结论：裂隙正颌手术的复杂程度和方法与常规正颌手术不同，但这些结果表明，咬合结果仍可与非裂隙人群进行比较。结果数据可用于与其他提供唇裂正颌治疗的中心进行比较。

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引用次数: 0

Effects of Toothpaste Containing 2% Zinc Citrate on Gingival Health and Three Related Bacteria—A Randomized Double-Blind Study 含 2% 柠檬酸锌的牙膏对牙龈健康和三种相关细菌的影响--随机双盲研究

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-04 DOI: 10.1002/cre2.70020

Yujie Zhou, Yi Zhou, Binyou Liao, Xiaobin Chen, Yulong Niu, Biao Ren

Objectives

Gingivitis is the initial stage of periodontitis, one of the most common oral diseases and the primary cause of tooth loss. This study aims to evaluate the effect of toothpaste containing 2% zinc citrate on gingival health and the abundance of three bacteria related to gingivitis and periodontitis.

Methods and Materials

Eleven volunteers with the same oral health status were randomly assigned to the treatment (n = 5) and control (n = 6) groups. The control group used fluoride toothpaste, while the treatment group used fluoride toothpaste supplemented with 2% zinc citrate for 3 months. The plaque index, gingival index, and bleeding index were measured at baseline (0 day), 3 weeks, and 3 months. Dental plaque from four areas of the mouth (FDI criteria) was collected at the same timepoints. A total of 132 dental plaque samples were analyzed using quantitative PCR (qPCR) to monitor the abundance of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythia.

Results

Toothpaste containing 2% zinc citrate significantly lowered the gingival index and reduced gum bleeding but did not affect the plaque index. It also reduced the total abundance of the three bacteria related to gingivitis and periodontitis in dental plaque over a long-term period.

Conclusions

Toothpaste with 2% zinc citrate persistently improves gingival health and reduces the presence of gingivitis-associated bacteria in dental plaque.

Trial Registration

Chinese Clinical Trial Registry (Clinical trial registration no.: ChiCTR1900020592) (09/01/2019).

目的：牙龈炎是牙周炎的初期阶段，牙周炎是最常见的口腔疾病之一，也是导致牙齿脱落的主要原因。本研究旨在评估含 2% 柠檬酸锌的牙膏对牙龈健康以及与牙龈炎和牙周炎有关的三种细菌数量的影响：将 11 名口腔健康状况相同的志愿者随机分配到治疗组（5 人）和对照组（6 人）。对照组使用含氟牙膏，治疗组使用含氟牙膏并添加 2% 柠檬酸锌，为期 3 个月。分别在基线（0 天）、3 周和 3 个月时测量牙菌斑指数、牙龈指数和出血指数。在相同的时间点收集口腔四个部位的牙菌斑（FDI 标准）。共对 132 份牙菌斑样本进行了定量 PCR（qPCR）分析，以监测放线杆菌、牙龈卟啉单胞菌和连翘丹那菌的数量：结果：含 2% 柠檬酸锌的牙膏能明显降低牙龈指数，减少牙龈出血，但不影响牙菌斑指数。它还能长期降低牙菌斑中与牙龈炎和牙周炎有关的三种细菌的总含量：结论：含2%柠檬酸锌的牙膏可持续改善牙龈健康，减少牙菌斑中牙龈炎相关细菌的数量：中国临床试验注册中心（临床试验注册号：ChiCTR1900020592）（09/01/2019）。

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引用次数: 0

Low-Dose Cone-Beam Computed Tomography in Swedish Pediatric Patients With Alveolar Clefts Following Alveolar Bone Grafting—A Clinical Study 瑞典牙槽骨移植术后牙槽骨裂隙儿科患者的低剂量锥形束计算机断层扫描--临床研究

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-04 DOI: 10.1002/cre2.70021

António Vicente, Josefine Cederhag, Nilofar Rashidi, Anna-Paulina Wiedel, Magnus Becker, Susanne Brogårdh-Roth, Xie-Qi Shi, Kristina Hellén-Halme

Objectives

The aim of this study was to investigate whether a low-dose cone-beam computed tomography (CBCT) protocol provides diagnostically acceptable image quality for assessing bone healing after alveolar bone grafting.

Material and Methods

The study cohort comprised 11 patients (aged 7–14 years) with orofacial clefts who had undergone alveolar bone grafting at Skåne University Hospital in Malmö, Sweden. During the postsurgical follow-up at 6 months, each patient was assessed twice: once with a standard-dose CBCT protocol and once with a low-dose CBCT protocol, which in total corresponds to one CBCT examination made with the exposure settings recommended by the manufacturer. Among others, the assessed parameters included subjective image quality, as well as bone graft height, thickness, and integration.

Results

No significant differences were found between the standard- and low-dose protocols for most parameters (p > 0.05). Exceptions included subjective image quality (one observer, p = 0.05) and confidence levels during the assessment (three observers, p = 0.01, 0.01, 0.02).

Conclusions

The low-dose protocol yielded adequate image quality for postoperative CBCT healing assessment in patients who have undergone alveolar bone grafting. However, the confidence level of observers during the assessment with the low-dose protocol was reduced. This study is registered on ClinicalTrials.gov (NCT06395077).

Clinical Trial Registration

This study is registered on ClinicalTrials.gov (NCT06395077).

研究目的本研究旨在探讨低剂量锥束计算机断层扫描（CBCT）方案能否为评估牙槽骨移植术后的骨愈合提供诊断上可接受的图像质量：研究对象包括在瑞典马尔默斯科纳大学医院接受牙槽骨移植手术的11名口面部裂患者（7-14岁）。在手术后 6 个月的随访期间，每位患者都接受了两次评估：一次是标准剂量 CBCT 方案，另一次是低剂量 CBCT 方案。评估参数包括主观图像质量以及植骨高度、厚度和整合度：结果：标准剂量和低剂量方案在大多数参数上无明显差异（P>0.05）。例外情况包括主观图像质量（一名观察者，p = 0.05）和评估过程中的信心水平（三名观察者，p = 0.01、0.01、0.02）：低剂量方案为接受牙槽骨移植术的患者术后 CBCT 愈合评估提供了足够的图像质量。结论：低剂量方案可为接受牙槽骨移植术的患者术后 CBCT 愈合评估提供足够的图像质量，但在使用低剂量方案进行评估时，观察者的信心水平有所下降。本研究已在 ClinicalTrials.gov (NCT06395077).Clinical trial registration 上注册：本研究已在 ClinicalTrials.gov (NCT06395077) 上注册。

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引用次数: 0

Management of Soft Tissue Defects Around Single Implants: A Systematic Review of the Literature 单体植入物周围软组织缺损的处理：文献系统性综述。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-04 DOI: 10.1002/cre2.70003

Haithem Moussa, Wafa Nasri, Rania Gargouri, Afif Bouslema

Objectives

The aim of this systematic review was to assess the effectiveness of the available techniques for the management of peri-implant soft tissue defects around single implants in the anterior region.

Material and Methods

A comprehensive search was conducted in PubMed (MEDLINE), Web of Science (all databases), and Cochrane, using keywords and MeSH terms related to the topic. This systematic review included prospective interventional studies with a minimum of 10 patients and at least 6 months of follow-up.

Results

A total of 13 articles were included, with eight focusing on outcomes related to buccal soft tissue dehiscence coverage procedures and the remaining five investigating interventions aimed at augmenting soft tissue thickness. Coronally advanced flap in combination with connective tissue graft was the most effective technique for buccal soft tissue dehiscence coverage in the medium and long term. In terms of increasing soft tissue thickness, both connective tissue graft and acellular dermal matrix demonstrated satisfactory short-term outcomes; however, their long-term efficacy remains unclear.

Conclusions

Soft tissue augmentation procedures resulted in satisfactory outcomes, in terms of buccal soft tissue dehiscence coverage and soft tissue thickness increase, around single implants in the esthetic area. Peri-implant plastic surgery has improved both the esthetic appearance and quality of life of patients.

PROSPERO Registration Code

CRD42023398424

目的本系统综述旨在评估现有技术对前牙区单颗种植体周围软组织缺损治疗的有效性：使用与该主题相关的关键词和 MeSH 术语在 PubMed（MEDLINE）、Web of Science（所有数据库）和 Cochrane 中进行了全面检索。该系统性综述包括至少有 10 名患者和至少 6 个月随访的前瞻性干预研究：结果：共纳入了 13 篇文章，其中 8 篇侧重于与颊软组织开裂覆盖程序相关的结果，其余 5 篇调查了旨在增加软组织厚度的干预措施。从中长期来看，冠状突起皮瓣结合结缔组织移植是最有效的颊软组织开裂覆盖技术。在增加软组织厚度方面，结缔组织移植和非细胞真皮基质都取得了令人满意的短期效果，但其长期疗效仍不明确：软组织增量手术在口腔软组织开裂覆盖率和软组织厚度增加方面都取得了令人满意的效果。种植体周围整形手术改善了患者的美学外观和生活质量：CRD42023398424。

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引用次数: 0

Experimental Periodontitis Increases Anxious Behavior and Worsens Cognitive Aspects and Systemic Oxidative Stress in Wistar Rats 实验性牙周炎会增加 Wistar 大鼠的焦虑行为并恶化其认知能力和全身氧化应激。

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research

Pub Date : 2024-11-04 DOI: 10.1002/cre2.70017

Giselle B. de Castro, Ramona R. S. Pereira, Caíque O. Diniz e Magalhães, Karine B. Costa, Etel R. Vieira, Ricardo C. Cassilhas, Kinulpe H. Sampaio, Alan R. T. Machado, Jaqueline do Carmo L. Carvalho, Ramiro M. Murata, Luciano J. Pereira, Marco F. Dias-Peixoto, Eric F. Andrade, Vanessa Pardi

Objectives

Periodontitis (PD) has the potential to induce systemic changes that affect both physical and behavioral aspects. These alterations may be associated with changes in both the inflammatory profile and the oxidative stress status of individuals with PD. Therefore, we aimed to evaluate the effects of PD on oxidative stress, as well as on behavioral parameters and cognitive impairment, in a preclinical model.

Material and Methods

Twenty-four male Wistar rats were randomly assigned to PD and sham groups. PD was induced by the ligature protocol for 14 days. Behavioral tests were initiated on the 9th day of the experiment to evaluate anxious behavior and cognition (learning and memory). After euthanasia, oxidative stress was evaluated in the gums, blood, hippocampus, and amygdala. Alveolar bone loss, bone microstructure, and elemental compositions of the mandibular bone were also assessed.

Results

PD increased alveolar bone loss, reduced the calcium and phosphorus content in the mandibular bone, and increased anxiety-like behavior and cognitive decline (p < 0.05). Furthermore, PD significantly affected the redox balance, as evidenced by increased total antioxidant capacity (TAC) in the gingiva and hippocampus (p < 0.05). It also led to increased lipid peroxidation in the gingiva and erythrocytes (p < 0.05), decreased antioxidant defenses in erythrocytes (superoxide dismutase) and the hippocampus (catalase), and increased antioxidant activity (catalase) in the amygdala (p < 0.05).

Conclusion

PD resulted in cognitive alterations, including impairments in spatial learning and memory, as well as increased anxious behavior, likely due to redox imbalance in rats.

目的：牙周炎（PD）有可能诱发影响身体和行为的全身性变化。这些变化可能与牙周炎患者的炎症特征和氧化应激状态的变化有关。因此，我们的目的是在临床前模型中评估帕金森病对氧化应激以及行为参数和认知障碍的影响：24只雄性Wistar大鼠被随机分配到PD组和假组中。通过结扎方案诱导腹膜透析 14 天。实验第 9 天开始进行行为测试，以评估大鼠的焦虑行为和认知能力（学习和记忆）。安乐死后，对牙龈、血液、海马和杏仁核中的氧化应激进行评估。此外，还对下颌骨的牙槽骨损失、骨微结构和元素组成进行了评估：结果：PD 增加了牙槽骨损失，降低了下颌骨中的钙和磷含量，并增加了焦虑样行为和认知能力下降（p 结论：PD 导致认知能力改变，包括认知障碍和认知缺陷：白内障导致认知改变，包括空间学习和记忆障碍，以及焦虑行为增加，这可能是由于大鼠体内氧化还原失衡所致。

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引用次数: 0