Clinical and Experimental Dental Research最新文献_第6页

Comparing the effects of Bone+B® xenograft and InterOss® xenograft bone material on rabbit calvaria bone defect regeneration 比较 Bone+B® 异种移植骨材料和 InterOss® 异种移植骨材料对兔小腿骨缺损再生的影响。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-26 DOI: 10.1002/cre2.875

Afshin Yadegari Naini, Sepehr Kobravi, Aida Jafari, Mohammadhassan Lotfalizadeh, Narges Lotfalizadeh, Sareh Farhadi

Background

The bone regeneration therapy is often used in patients with inadequate bone support for implants, particularly following tooth extractions. Xenografts derived from animal tissues are effective bone reconstructive options that resist resorption and pose a low risk of transmitting disease. Therefore, these implants may be a good option for enhancing and stabilizing maxillary sinuses. The purpose of this study was to compare two xenografts, Bone⁺B® and InterOss®, for the reconstruction of rabbit calvaria defects.

Methods and Materials

The study involved seven male New Zealand white rabbits. In the surgical procedure, 21 spots were created on both sides of the midline calvarium by creating three 8-millimeter defects. A control group was used, as well as two treatment groups utilizing Bone⁺B® Grafts and InterOss® Grafts. After 3 months, the rabbits were euthanized, followed by pathological evaluation. Analysis of these samples focused on bone formation, xenograft remaining material, and inflammation levels, using Adobe Photoshop CS 8.0 and SPSS version 24.

Results

With the application of Bone⁺B® graft, bone formation ranged from 32% to 45%, with a mean of 37.80% (±5.63), and the remaining material ranged from 28% to 37%, with a mean of 32.60% (±3.65). Using InterOss® grafts, bone formation was 61% to 75%, the mean was 65.83% (±4.75), and the remaining material was 9% to 18%, with a mean of 13.17% (±3.06). The bone formation in the control group ranged from 10% to 25%, with a mean of 17.17% (±6.11). InterOss® had lower inflammation levels than other groups, but the difference was not statistically significant (p > .05).

Conclusion

InterOss® bone powder is the best option for maxillofacial surgery and bone reconstruction. This is due to more bone formation, less remaining material, and a lower inflammation level. Compared to the control group, Bone⁺B® improves healing and bone quality, thus making it an alternative to InterOss®.

背景：骨再生疗法常用于种植体骨支持不足的患者，尤其是拔牙后的患者。从动物组织中提取的异种移植物是一种有效的骨重建选择，它能抵抗吸收，传播疾病的风险也很低。因此，这些种植体可能是增强和稳定上颌窦的良好选择。本研究的目的是比较 Bone+B® 和 InterOss® 两种异种移植物在兔腭窦缺损重建中的应用：这项研究涉及七只雄性新西兰白兔。在手术过程中，通过在小腿中线两侧创建三个 8 毫米的缺损，共创建了 21 个点。分为对照组以及使用 Bone+B® 人工骨和 InterOss® 人工骨的两个治疗组。3 个月后，兔子被安乐死，然后进行病理评估。使用 Adobe Photoshop CS 8.0 和 SPSS 24.0 版对这些样本进行分析，重点关注骨形成、异种移植剩余材料和炎症水平：使用 Bone+B® 移植物时，骨形成率为 32% 至 45%，平均值为 37.80%（±5.63），剩余材料率为 28% 至 37%，平均值为 32.60%（±3.65）。使用 InterOss® 移植物时，骨形成率为 61% 至 75%，平均为 65.83%（±4.75），剩余材料为 9% 至 18%，平均为 13.17%（±3.06）。对照组的骨形成率为 10%-25%，平均为 17.17%（±6.11）。InterOss®骨粉的炎症水平低于其他组，但差异无统计学意义（P > .05）：结论：InterOss® 骨粉是颌面手术和骨重建的最佳选择。结论：InterOss® 骨粉是颌面手术和骨重建的最佳选择，因为它能形成更多的骨，减少剩余材料，降低炎症水平。与对照组相比，Bone+B® 可改善愈合和骨质，因此可作为 InterOss® 的替代品。

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引用次数: 0

A preliminary study on calcifying nanoparticles in dental plaque: Isolation, characterization, and potential mineralization mechanism 牙菌斑中钙化纳米粒子的初步研究：牙菌斑中钙化纳米粒子的初步研究：分离、表征和潜在矿化机制。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-26 DOI: 10.1002/cre2.885

Siwei Wang, Lan Yang, Guohui Bai, Yu Gu, Qin Fan, Xiaoyan Guan, Jie Yuan, Jianguo Liu

Objectives

Calcifying nanoparticles (CNPs), referred to as nanobacteria (NB), are recognized to be associated with ectopic calcification. This study aims to isolate and culture CNPs from the dental plaque of patients with periodontal disease and investigate their possible role in unravelling the aetiology of periodontal disease.

Material and Methods

Supragingival and subgingival plaques were sampled from 30 periodontitis patients for CNPs isolation and culture. Alkaline phosphatase (ALP) content changes were tracked over time. Positive samples underwent thorough morphological identification via hematoxylin and eosin (HE) staining, Alizarin red S (ARS), and transmission electron microscopy (TEM). The chemical composition of CNPs analysis involved calcium (Ca) and phosphorus (P) content determination, Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD).

Results

The subgingival plaque dental group exhibited a higher CNPs isolation rate at 36.67% (11/30) compared to the supragingival dental plaque group at 66.67% (20/30). ALP activity varied among the positive, negative and control groups. Morphological observation characterized the CNPs as round, oval, and ellipsoid particles with Ca deposits. Chemical analysis revealed the Ca/P ratio was 0.6753. Hydroxyl, methyl, carbonate, phosphate, hydrogen phosphate, and dihydrogen phosphate were detected by FTIR; the main chemical components detected by XRD were hydroxyapatite and tricalcium phosphate.

Conclusion

CNPs were found in periodontitis-related dental plaque and exhibited the potential to develop calcified structures resembling dental calculus. However, the potential involvement of ALP in CNPs formation requires deeper exploration, as does the precise nature of its role and the interrelation with periodontitis demand a further comprehensive investigation.

目的：钙化纳米颗粒（CNPs）被称为纳米细菌（NB），公认与异位钙化有关。本研究旨在从牙周病患者的牙菌斑中分离和培养 CNPs，并研究它们在揭示牙周病病因方面可能发挥的作用：材料和方法：从30名牙周炎患者的龈上和龈下牙菌斑中取样，进行CNPs的分离和培养。跟踪碱性磷酸酶（ALP）含量随时间的变化。通过苏木精和伊红（HE）染色、茜素红 S（ARS）和透射电子显微镜（TEM）对阳性样本进行彻底的形态鉴定。CNPs 的化学成分分析包括钙（Ca）和磷（P）含量测定、傅立叶变换红外光谱（FTIR）和 X 射线衍射（XRD）：龈下牙菌斑组的 CNPs 分离率为 36.67%（11/30），而龈上牙菌斑组为 66.67%（20/30）。阳性组、阴性组和对照组的 ALP 活性各不相同。形态观察显示，CNPs 有圆形、椭圆形和椭圆形颗粒，并有钙沉积。化学分析显示，钙/磷比率为 0.6753。傅立叶变换红外光谱检测到羟基、甲基、碳酸盐、磷酸盐、磷酸氢盐和磷酸二氢盐；X射线衍射检测到的主要化学成分是羟基磷灰石和磷酸三钙：结论：在牙周炎相关牙菌斑中发现了 CNPs，并有可能形成类似牙结石的钙化结构。然而，ALP 可能参与了 CNPs 的形成，这需要更深入的探讨，其作用的确切性质以及与牙周炎的相互关系也需要进一步的全面研究。

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引用次数: 0

Comparing the efficacy of a novel mucoadhesive patch containing Nigella sativa 10% with triamcinolone 0.1% in patients with erosive-atrophic oral lichen planus: A pilot study 在侵蚀性-萎缩性口腔扁平苔藓患者中比较含有 10%黑升麻的新型粘液贴片与 0.1% 曲安奈德的疗效：试点研究。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-26 DOI: 10.1002/cre2.886

Atessa Pakfetrat, Zahra Delavarian, Mahshid Malakooti, Hossein Bagheri, Habibollah Esmaily, Mahsa Ghorbani, Pooya Saeedi

Objective

This study evaluates the efficacy of a novel mucoadhesive patch containing Nigella sativa 10% extract compared to triamcinolone 0.1% in alleviating symptoms and reducing lesion severity in patients with erosive-atrophic oral lichen planus.

Methods and Materials

A pilot study comprising two groups, each with 10 patients, was conducted. The intervention group received mucoadhesive patches containing N. sativa 10% extract, while the control group received triamcinolone acetonide 0.1% patches. Pain and burning intensity, measured through visual analog scale, and lesion severity based on the Thongprasom scale were assessed weekly for 4 weeks. Descriptive records were kept for side effects and patient satisfaction.

Results

Pain and burning intensity decreased in both groups throughout the sessions, with the N. sativa group showing a greater reduction than the triamcinolone group. The reduction in burning intensity within each group was significant (p < .001), and there was a significant difference between groups only in the second session (p = .045). The overall difference between groups was not significant (p > .05). Lesion severity also decreased significantly in both groups (p < .001), with a significant difference between groups observed in the third session (p = .043) and overall throughout the study (p = .006).

Conclusion

The use of N. sativa extract in mucoadhesive patches was as effective as corticosteroids in reducing pain, burning, and lesion severity in patients with oral lichen planus, with N. sativa showing superior results in some sessions. Notably, no significant complications were observed with N. sativa use, making it a promising treatment option for lichen planus.

研究目的本研究评估了含有 10%黑升麻提取物的新型粘液贴片与 0.1% 曲安奈德相比，在缓解侵蚀性-萎缩性口腔扁平苔藓患者症状和降低皮损严重程度方面的疗效：试验研究包括两组，每组 10 名患者。干预组使用含 10%荠菜提取物的粘液贴片，对照组使用 0.1% 曲安奈德贴片。通过视觉模拟量表测量疼痛和烧灼感的强度，并根据 Thongprasom 量表评估病变的严重程度，每周评估一次，持续 4 周。对副作用和患者满意度进行描述性记录：结果：在整个疗程中，两组患者的疼痛和灼烧感都有所减轻，其中藜芦组的减轻幅度大于曲安奈德组。各组的灼烧强度均有显著降低（P .05）。两组的皮损严重程度也都明显减轻（p 结论：N.Sativa 提取物和三苯氧胺组的皮损严重程度都明显减轻：在减轻口腔扁平苔藓患者的疼痛、灼烧感和皮损严重程度方面，粘贴贴片中的荠菜提取物与皮质类固醇同样有效，而且在某些疗程中荠菜提取物的效果更好。值得注意的是，使用 N. sativa 没有观察到明显的并发症，使其成为治疗扁平苔藓的一种很有前景的选择。

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引用次数: 0

Optimizing esthetic zone periodontal regeneration in a 1–2-wall infrabony defect using recombinant human platelet-derived growth factor BB and β-tricalcium phosphate: A case report 使用重组人血小板衍生生长因子 BB 和 β-磷酸三钙优化 1-2 壁牙周缺损中的美学区牙周再生：病例报告。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-26 DOI: 10.1002/cre2.908

Kantapon Rattanaprukskul, Rodrigo Neiva, Jonathan Korostoff

Objective

Periodontitis is an inflammatory condition induced by subgingival bacterial dysbiosis, resulting in inflammatory-mediated destruction of tooth-supporting structures, potentially leading to the formation of infrabony defects. This case report describes the treatment of a patient who presented with a combination 1–2-wall defect on tooth 21. To maintain the residual periodontal attachment and minimize esthetic consequences, a regenerative approach was performed using recombinant human platelet-derived growth factor-BB (rh-PDGF-BB) and β-tricalcium phosphate (β-TCP).

Materials and Methods

At the time of postscaling/root planing reevaluation, a 34-year-old Asian male initially diagnosed with molar/incisor pattern stage III grade C periodontitis exhibited a 6-mm residual probing depth on the mesiopalatal aspect of tooth 21. Periodontal regenerative surgery was performed using rh-PDGF-BB with β-TCP, without the use of a membrane.

Results

At the 1-year follow-up, a significant reduction in probing depth and radiographic evidence of bone fill were observed. Additionally, re-entry surgery for implant placement at site tooth 23 confirmed bone fill in the defect on tooth 21.

Conclusion

These results demonstrate the efficacy of rh-PDGF-BB with β-TCP in enhancing periodontal regeneration and support its use as a treatment option when treating poorly contained infrabony defects in the esthetic zone.

目的：牙周炎是由龈下细菌菌群失调引起的炎症，导致炎症介导的牙齿支持结构破坏，并可能形成牙槽骨下缺损。本病例报告描述了对一名 21 号牙 1-2 壁联合缺损患者的治疗。为了维持残余的牙周附着并尽量减少美观后果，我们使用重组人血小板衍生生长因子-BB（rh-PDGF-BB）和β-磷酸三钙（β-TCP）进行了再生治疗：一名 34 岁的亚裔男性在进行洗牙/根面平整术后复查时，初步诊断为臼齿/incisor 模式 III 期 C 级牙周炎，其第 21 号牙齿中腭侧的探诊深度残留 6 毫米。在不使用牙膜的情况下，使用 rh-PDGF-BB 和 β-TCP进行了牙周再生手术：随访 1 年后，探诊深度明显降低，X 光片显示骨填充。此外，在第 23 颗牙齿部位再次进行种植手术时，证实了第 21 颗牙齿缺损处的骨填充情况：这些结果表明，rh-PDGF-BB 和 β-TCP 能有效促进牙周再生，并支持将其作为治疗美观区内骨缺损的一种治疗方法。

{"title":"Optimizing esthetic zone periodontal regeneration in a 1–2-wall infrabony defect using recombinant human platelet-derived growth factor BB and β-tricalcium phosphate: A case report","authors":"Kantapon Rattanaprukskul, Rodrigo Neiva, Jonathan Korostoff","doi":"10.1002/cre2.908","DOIUrl":"10.1002/cre2.908","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Periodontitis is an inflammatory condition induced by subgingival bacterial dysbiosis, resulting in inflammatory-mediated destruction of tooth-supporting structures, potentially leading to the formation of infrabony defects. This case report describes the treatment of a patient who presented with a combination 1–2-wall defect on tooth 21. To maintain the residual periodontal attachment and minimize esthetic consequences, a regenerative approach was performed using recombinant human platelet-derived growth factor-BB (rh-PDGF-BB) and β-tricalcium phosphate (β-TCP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>At the time of postscaling/root planing reevaluation, a 34-year-old Asian male initially diagnosed with molar/incisor pattern stage III grade C periodontitis exhibited a 6-mm residual probing depth on the mesiopalatal aspect of tooth 21. Periodontal regenerative surgery was performed using rh-PDGF-BB with β-TCP, without the use of a membrane.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At the 1-year follow-up, a significant reduction in probing depth and radiographic evidence of bone fill were observed. Additionally, re-entry surgery for implant placement at site tooth 23 confirmed bone fill in the defect on tooth 21.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These results demonstrate the efficacy of rh-PDGF-BB with β-TCP in enhancing periodontal regeneration and support its use as a treatment option when treating poorly contained infrabony defects in the esthetic zone.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.908","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative effects of glazing versus polishing on mechanical, optical, and surface properties of zirconia ceramics with different translucencies 上釉与抛光对不同透光度氧化锆陶瓷的机械、光学和表面特性的比较效果。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-26 DOI: 10.1002/cre2.884

Dr Maryam Jamali DDS,MSc, Dr Fariba Ezoji DDS,MSc, Dr Behnaz Esmaeili DDS,MSc, Soraya Khafri Phd

Objectives

This study compared the effects of glazing versus polishing on mechanical, optical, and surface properties of zirconia ceramics with different translucencies.

Materials and Methods

In this in vitro study, 120 bar-shaped specimens (25 × 4 × 1.2 mm) were fabricated from three different types of zirconia with different translucencies (n = 40, DD Bio ZW, ZX2, and Cube X2). After sintering, each zirconia group was randomly divided into five subgroups of control (glazing), glazing + bur abrasion, glazing + bur abrasion + polishing with EVE Diacera® kit, glazing + bur abrasion + reglazing, and glazing + bur abrasion + polishing with EVE Diacera® kit + reglazing. The specimens underwent surface roughness, hardness, flexural strength, and translucency tests, as well as X-ray diffraction (XRD) and scanning electron microscopy (SEM) for assessment of surface topography. Data were analyzed by one-way analysis of variance, Tukey test, and Pearson test (α = .05).

Results

Flexural strength, surface hardness, and translucency were significantly correlated with zirconia type. ZW zirconia had significantly higher flexural strength and surface hardness and significantly lower translucency than Cube X2 and ZX2 (p < .001). Surface roughness had no significant correlation with zirconia type (p = .274). Polishing created the smoothest, and bur abrasion created the roughest surface (p < .001). Flexural strength and hardness in most experimental groups were significantly lower than in the control group (p < .001). Translucency was not significantly different in bur abrasion and polishing groups, compared with the control group; however, reglazing significantly increased the translucency (p < .001). SEM micrographs confirmed the surface roughness results. XRD showed monoclinic phase only in reglazed groups.

Conclusion

Of different surface treatments, polishing improved the surface properties and caused the smallest change in mechanical properties of zirconia with different translucencies.

目的：比较上釉和抛光对不同透光度氧化锆陶瓷的机械、光学和表面特性的影响：本研究比较了施釉与抛光对不同透光度氧化锆陶瓷的机械、光学和表面特性的影响：在这项体外研究中，我们用三种不同透光度的氧化锆（n = 40，DD Bio ZW、ZX2 和 Cube X2）制作了 120 个棒状试样（25 × 4 × 1.2 毫米）。烧结后，每组氧化锆被随机分为五个子组：对照组（上釉）、上釉 + 毛刺磨损组、上釉 + 毛刺磨损 + 使用 EVE Diacera® 套件抛光组、上釉 + 毛刺磨损 + 再上釉组和上釉 + 毛刺磨损 + 使用 EVE Diacera® 套件抛光 + 再上釉组。试样进行了表面粗糙度、硬度、抗弯强度和透光度测试，并使用 X 射线衍射 (XRD) 和扫描电子显微镜 (SEM) 评估表面形貌。数据分析采用单因素方差分析、Tukey 检验和 Pearson 检验（α = .05）：结果：抗弯强度、表面硬度和半透明度与氧化锆类型显著相关。与 Cube X2 和 ZX2 相比，ZW 型氧化锆的抗弯强度和表面硬度明显更高，而透光度则明显更低（p）：在不同的表面处理方法中，抛光能改善氧化锆的表面性能，对不同半透明氧化锆的机械性能造成的变化最小。

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引用次数: 0

The influence of Zircos-E® etchant, silica coating, and alumina air-particle abrasion on the debonding resistance of endocrowns with three different preparation designs Zircos-E®蚀刻剂、二氧化硅涂层和氧化铝气粒磨损对三种不同制备设计的内冠的抗脱落性的影响。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-21 DOI: 10.1002/cre2.901

Ahmed Yaseen Alqutaibi, Mohammed Ahmed Alghauli, Karim Dewedar, Mohammed H. AbdElaziz, Samah Saker

Objectives

The study aimed to evaluate the debonding resistance of three different endocrown designs on molar teeth, using three different zirconia surface pretreatments.

Material and Method

Ninety human mandibular first molars were divided into three main groups: endocrowns without ferrule, with 1 mm ferrule, and with 2 mm ferrule. The subgroups were defined by their surface pretreatment method used (n = 15): 50 μm alumina air-particle abrasion, silica coating using 30 μm Cojet™ particles, and Zircos-E® etching. The endocrowns were fabricated using multilayer zirconia ceramic, cemented with self-adhesive resin cement, and subjected to 5000 thermocycles (5–55°C) before debonding. The data obtained were analyzed using a two-way ANOVA.

Results

All test specimens survived the thermocyclic aging. The results indicated that both the preparation design and the surface treatment had a significant impact on the resistance to debonding of the endocrowns (p < .001). The 2 mm ferrule followed by the 1 mm ferrule designs exhibited the highest debonding resistance, both were superior to the endocrown without ferrule. Zircos-E® etching and silica coating yielded comparable debonding resistance, which were significantly higher than alumina air-particle abrasion. All endocrowns demonstrated a favorable failure mode.

Conclusions

All designs and surface treatments showed high debonding resistance for a single restoration. However, ferrule designs with Zircos-E® etching or silica coating may represent better clinical options compared to the nonferrule design or alumina airborne-particle abrasion. Nonetheless, further research, including fatigue testing and evaluations with different luting agents is recommended.

研究目的该研究旨在评估三种不同氧化锆表面预处理的磨牙内冠设计的抗脱落性：将 90 颗人类下颌第一磨牙分为三大组：无套圈内冠、带 1 毫米套圈内冠和带 2 毫米套圈内冠。根据所使用的表面预处理方法（n = 15）来确定分组：50 μm 氧化铝空气颗粒研磨、使用 30 μm Cojet™ 颗粒的二氧化硅涂层和 Zircos-E® 蚀刻。使用多层氧化锆陶瓷制作内冠，用自粘树脂粘结剂粘结，并在脱粘前进行 5000 次热循环（5-55°C）。所得数据采用双向方差分析：结果：所有试样都经受住了热循环老化。结果表明，制备设计和表面处理对内冠的抗脱落性都有显著影响（p 结论：所有设计和表面处理都显示出较高的抗脱落性：对于单个修复体而言，所有的设计和表面处理都显示出较高的抗脱落性。不过，与非卡环设计或氧化铝空气颗粒磨蚀相比，带有 Zircos-E® 蚀刻或二氧化硅涂层的卡环设计可能是更好的临床选择。尽管如此，还是建议进行进一步的研究，包括疲劳测试和使用不同粘结剂的评估。

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引用次数: 0

The extended finite element method in endodontics: A scoping review and future directions for cyclic fatigue testing of nickel–titanium instruments 牙髓学中的扩展有限元法：镍钛器械循环疲劳测试的范围综述和未来方向。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-21 DOI: 10.1002/cre2.893

Philip Yuan-Ho Chien, Laurence James Walsh, Ove Andreas Peters

Objectives

The present study reviews the current literature regarding the utilization of the extended finite element method (XFEM) in clinical and experimental endodontic studies and the suitability of XFEM in the assessment of cyclic fatigue in rotary endodontic nickel–titanium (NiTi) instruments.

Material and Methods

An electronic literature search was conducted using the appropriate search terms, and the titles and abstracts were screened for relevance. The search yielded 13 hits after duplicates were removed, and four studies met the inclusion criteria for review.

Results

No studies to date have utilized XFEM to study cyclic fatigue or crack propagation in rotary endodontic NiTi instruments. Challenges such as modelling material inputs and fatigue criteria could explain the lack of utilization of XFEM in the analysis of mechanical behavior in NiTi instruments.

Conclusions

The review showed that XFEM was seldom employed in endodontic literature. Recent work suggests potential promise in using XFEM for modelling NiTi structures.

研究目的本研究回顾了有关在临床和实验性牙髓研究中使用扩展有限元法（XFEM）的现有文献，以及 XFEM 在评估旋转式牙髓镍钛（NiTi）器械的循环疲劳方面的适用性：使用适当的检索词进行了电子文献检索，并对标题和摘要进行了相关性筛选。去除重复内容后，共搜索到 13 篇文章，其中 4 篇符合纳入审查标准：迄今为止，还没有研究利用 XFEM 来研究旋转式根管治疗镍钛器械的循环疲劳或裂纹扩展。材料输入建模和疲劳标准等挑战可能是 XFEM 在镍钛器械机械行为分析中缺乏应用的原因：综述显示，牙髓文献中很少使用 XFEM。最近的研究表明，使用 XFEM 对镍钛结构建模具有潜在的前景。

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引用次数: 0

Evaluation of the effect of different core substrates on the accuracy of intraoral scanners 评估不同牙芯基底对口内扫描仪精度的影响。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-16 DOI: 10.1002/cre2.899

Maryam Khoshkhahesh, Shabnam Enteghad, Kiana Aghasadeghi, Mitra Farzin, Masumeh Taghva, Seyed Ali Mosadad

Background

The aim of this study was to determine if different types of core substrates have any effect on the trueness and precision of digital intraoral impressions.

Material and Methods

A customized typodont with four similar cores of natural dentine, composite, metal (Ni-Cr), and zirconia in the position of premolars was fabricated. The study model was scanned five times with two types of intraoral scanners (Carestream 3600 and 3Shape Trios 3), and a reference standard scan was obtained using a laboratory scanner (3shape D1000). A metrology software (Geomagic X) was used to align the data of experimental scans and the reference scan to determine deviation values (trueness). Precision values were calculated with random superimposition in each intraoral scanner group. The Kruskal–Wallis test was used to compare differences between different substrates, and the Mann–Whitney test was used to compare the average values between the two scanners.

Results

Trios 3 was found to be significantly truer and more precise than Carestream 3600 (p value = .005, <0.001). There were no significant differences in the trueness of different substrates when they were scanned by Trios 3, while different materials showed significantly different trueness values in the Carestream 3600 group (p value = .003). Dentin showed the best trueness, and zirconia performed worse than other substrates. Regarding the precision of the scanners, neither of the scanners was affected by the type of scanning substrate.

Conclusion

For Carestream 3600, substrate type did impact the trueness of intraoral scans, with dentin and zirconia showing the highest and lowest accuracy, respectively, while Trios 3 was similarly accurate across all substrates. Trios 3 had both higher trueness and precision than Carestream 3600.

背景：本研究的目的是确定不同类型的牙髓基底是否会对数字化口内印模的真实性和精确性产生影响：在前臼齿的位置上制作了一个定制的类型牙，有天然牙本质、复合材料、金属（镍铬合金）和氧化锆四种类似的牙髓。使用两种口内扫描仪（Carestream 3600 和 3Shape Trios 3）对研究模型进行了五次扫描，并使用实验室扫描仪（3shape D1000）进行了参考标准扫描。使用计量软件（Geomagic X）对实验扫描数据和参考扫描数据进行对齐，以确定偏差值（真实度）。每个口内扫描仪组的精确度值都是通过随机叠加计算得出的。Kruskal-Wallis 检验用于比较不同基底之间的差异，Mann-Whitney 检验用于比较两种扫描仪之间的平均值：结果：Trios 3 的真实度和精确度明显高于 Carestream 3600（P 值 = .005，结论：对于 Carestream 3600，基质类型、基质类型、基质类型、基质类型、基质类型、基质类型、基质类型、基质类型、基质类型、基质类型、基质类型、基质类型）：对于 Carestream 3600，基质类型确实会影响口内扫描的真实度，牙本质和氧化锆的准确度分别最高和最低，而 Trios 3 对所有基质的准确度都差不多。Trios 3 的真实度和精确度均高于 Carestream 3600。

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引用次数: 0

Unique dietary and oral hygiene behaviors in a cohort with clinically severe obesity: A cross sectional study 临床重度肥胖人群独特的饮食和口腔卫生行为：一项横断面研究。

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-10 DOI: 10.1002/cre2.895

Zanab Malik, Woosung Sohn, Shanika Nanayakkara, Kathryn Williams

Background

An association between increased risk of dental caries with increased levels of clinically severe obesity has been reported. Data linking body mass index (BMI) and dietary behaviors, including at-risk dietary factors and oral hygiene habits, are lacking in a cohort with clinically severe obesity. This study aimed to explore the dietary and oral hygiene behaviors in individuals with clinically severe obesity attending a hospital-based obesity service.

Methods

Adult patients attending a hospital-based obesity service in Greater Western Sydney with clinically severe obesity were invited to participate in a self-administered survey, which collected data on their nutritional and oral hygiene behaviors. Demographic data (age, gender) and BMI were extracted from the participants' medical records. The primary outcome was the relationship between BMI and frequency of ^{toothbrushing.}

Results

Of the 82 individuals who consented to participate, 81 (98.8%) completed the study questionnaire. The median BMI of the cohort was 49.1 kg/m² (interquartile range [IQR]: 43.2–57.3 kg/m²) and median age 51 (IQR: 39–63) years. BMI was not significantly correlated with individual oral health behaviors (p > .05). Many participants reported dietary risk behaviors, which have the potential to influence their oral health.

Conclusions

While oral health behaviors were not associated with increasing BMI, patients with clinically severe obesity in this study reported unique dietary behaviors and mixed oral hygiene habits that may complicate nutritional and dental management. Awareness of these behaviors among clinicians including dental professionals is required in this cohort.

背景：据报道，龋齿风险的增加与临床重度肥胖程度的增加有关。在临床重度肥胖人群中，缺乏将体重指数（BMI）和饮食行为（包括高危饮食因素和口腔卫生习惯）联系起来的数据。本研究旨在探讨在医院肥胖症服务机构就诊的临床重度肥胖症患者的饮食和口腔卫生行为：方法：邀请到大悉尼西区一家医院肥胖症服务机构就诊的临床重度肥胖症成人患者参加一项自填式调查，收集他们的营养和口腔卫生行为数据。人口统计学数据（年龄、性别）和体重指数均从参与者的医疗记录中提取。主要结果是 BMI 与刷牙频率之间的关系。结果：在同意参与研究的 82 人中，81 人（98.8%）完成了研究问卷。人群的体重指数中位数为 49.1 kg/m2（四分位距 [IQR]：43.2-57.3 kg/m2），年龄中位数为 51（IQR：39-63）岁。体重指数与个人口腔健康行为无明显相关性（P > .05）。许多参与者报告了饮食风险行为，这有可能影响他们的口腔健康：虽然口腔健康行为与体重指数的增加无关，但本研究中的临床重度肥胖患者报告了独特的饮食行为和混合口腔卫生习惯，这可能会使营养和牙科管理复杂化。临床医生（包括牙科专业人员）需要对这些行为有所了解。

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引用次数: 0

Evaluation of the effects of postprocessing settings in digital bitewing radiographs on proximal caries detection 评估数字咬翼X光片后处理设置对近端龋齿检测的影响

IF 1.8 Q3 Dentistry

Clinical and Experimental Dental Research

Pub Date : 2024-05-07 DOI: 10.1002/cre2.889

Mehrdad Abdinian, Forooz Keshani, Fateme Sadeghi, Parisa Soltani, Gianrico Spagnuolo, Carlo Rengo

Objective

Radiographs are an integral part of detecting proximal caries. The aim of this study was to evaluate the effect of contrast, brightness, noise, sharpness, and γ adjustment of digital intraoral radiographs on the diagnosis of proximal caries.

Materials and methods

In this in vitro study, 40 extracted teeth including 20 premolars and 20 molars with enamel lesions (white spot or dentin discoloration seen through the enamel) were mounted together in groups of eight inside the skull. Bitewing radiographic images of each dental group were obtained by a photostimulable phosphor plate sensor with exposure conditions of 8 mA, 70 kV, and 0.2 s. The images were reconstructed by the built-in software and examined by two oral and maxillofacial radiologists in various settings of contrast, brightness, sharpness, noise, and γ. The teeth were then cut mesiodistally and the presence or absence of caries was confirmed by an oral and maxillofacial pathologist using a stereomicroscope. The data were then analyzed using the κ agreement coefficient, sensitivity, specificity, and accuracy (α = .05).

Results

Adjustment of brightness and contrast led to higher diagnostic performance with an accuracy of 82.5% and 83.8 (for observers 1 and 2, respectively) and 82.5% (for both observers), respectively. Noise adjustment was the least helpful approach for diagnosis of proximal dental caries among other adjustments, with an accuracy of 78.8% and 77.5% for observers 1 and 2, respectively.

Conclusion

Brightness and contrast setting was more efficient in improving the diagnostic potential of bitewing radiographs compared to other adjustments.

目的 X 光片是检测近端龋不可或缺的一部分。本研究旨在评估数字口内X光片的对比度、亮度、噪声、锐度和γ调整对诊断近端龋的影响。材料和方法在这项体外研究中，将 40 颗有釉质病变（透过釉质看到白斑或牙本质变色）的拔牙（包括 20 颗前臼齿和 20 颗臼齿）以 8 颗为一组装在头骨内。每组牙齿的咬翼射线图像都是通过光刺激荧光板传感器获得的，曝光条件为 8 mA、70 kV 和 0.2 秒。图像由内置软件重建，并由两名口腔颌面部放射科医生在不同的对比度、亮度、清晰度、噪声和 γ 设置下进行检查。然后在中线切开牙齿，由口腔颌面部病理学家使用体视显微镜确认是否存在龋齿。然后使用κ一致系数、灵敏度、特异性和准确性（α = .05）对数据进行分析。结果调整亮度和对比度可提高诊断性能，准确率分别为 82.5%、83.8%（观察者 1 和观察者 2）和 82.5%（两位观察者）。在其他调整中，噪声调整对诊断近端龋齿的帮助最小，观察者 1 和观察者 2 的准确率分别为 78.8% 和 77.5%。结论与其他调整相比，亮度和对比度设置能更有效地提高咬翼X光片的诊断潜力。

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引用次数: 0