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Long term changes in biometric parameters of eye with primary angle closure suspect after laser peripheral iridotomy 激光虹膜周围切开术后原发性闭角眼生物特征参数的长期变化
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.006
Li-xia Guo, Y. Liang, Da-peng Mu, Aiguo Lv, Si-zhen Li, Xin-jie Zang
Objective To quantitatively evaluate the long-term changes in biometric characteristics parameters after laser peripheral iridotomy (LPI) in primary angle closure suspect (PACS). Methods A prospective case series study. 40 PACS patients in Handan Eye Hospital, Hebei were enrolled in five years. LPI was performed in one eye selected randomly of every case (LPI group) , the other was as naturally control eye. Routine ophthalmic tests and A-scan examination were performed on both eyes at presentation、1 year and 5 year after LPI, including central anterior chamber depth (CACD),lens thickness (LT) and axial length (AL). Results Compared to before LPI, CACD was significantly deeper at 1 year, but more shallow at 5 year (all P<0.05). CACD in LPI group was more deeper than that in control group at 1 year, 5 year (P<0.05) . Within 5 years, CACD was grad-ually decreased, but the CACD at 5 year in the laser group was still bigger than that in the control group (P<0.05). LT in both team were thick gradually within 5 years (P<0.05) . Conclusions LPI can significantly deepen the central anterior chamber and delay the central anterior chamber shallow in PACS. Key words: primary angle closure suspect; laser peripheral iridotomy; lens
目的定量评价原发性闭角疑似患者激光虹膜周围切开术(LPI)术后生物特征参数的长期变化。方法前瞻性病例系列研究。选取河北省邯郸市眼科医院5年内PACS患者40例。每个病例随机选择一只眼(LPI组)进行LPI,另一只眼作为自然对照眼。就诊时、LPI术后1年和5年分别对双眼进行常规眼科检查和a扫描检查,包括中央前房深度(CACD)、晶状体厚度(LT)和眼轴长度(AL)。结果与LPI前比较,1年时CACD更深,5年时CACD更浅(均P<0.05)。LPI组在1年、5年的ccd深度高于对照组(P<0.05)。5年内,CACD逐渐下降,但激光组第5年的CACD仍大于对照组(P<0.05)。两组肝组织在5年内逐渐变厚(P<0.05)。结论LPI可使PACS中央前房明显加深,中央前房明显变浅。关键词:初级角闭合嫌疑;激光周围虹膜切开术;镜头
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引用次数: 0
The clinical features and curative effects of vasoproliferative retinal tumor 血管增生性视网膜肿瘤的临床特点及疗效分析
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.019
J. Qin, Yong Cheng
Objective To visualize the clinical features and investigate the major treatments and clinical cu-rative effects of vasoproliferative retinal tumor. Methods In these retrospective case series, 21 patients (22 eyes) were selected who were diagnosed as vasoproliferative retinal tumor between October 2005 and February 2015. The patients manifested as hemorrhage before or in the retinal. The patients were treated by different surgeries on the bases of ocular examinations such as B ultra-scan and fundus fluorescein angiography. Results Patients who were treated by intravitreal injection, radiation application, retinal freezing, laser photocoagu-lation or vitrectomy gained less fundus exudation and contraction tumors, with efficiencies of 50.00%, 50.00%, 66.67%, 83.33% and 77.78% respectively. Among which the effective rate of laser photocoagulation and vitrectomy were apparently higher than other therapies. Conclusions Photocoagulation and vitrectomy are good for the regression of vasoproliferative retinal tumor and can be applied clinically. Key words: Vasoproliferative retinal tumor; Clinical features; Therapeutic methods; Clinical effects
目的观察血管增殖性视网膜肿瘤的临床特点,探讨其主要治疗方法及临床疗效。方法回顾性分析2005年10月至2015年2月诊断为血管增殖性视网膜肿瘤的患者21例(22眼)。患者表现为视网膜前或视网膜内出血。根据B超扫描、眼底荧光素血管造影等眼部检查,对患者进行不同手术治疗。结果玻璃体内注射、放射应用、视网膜冷冻、激光光凝或玻璃体切除治疗的患者眼底渗出和收缩性肿瘤较少,有效率分别为50.00%、50.00%、66.67%、83.33%和77.78%。其中激光光凝和玻璃体切除术的有效率明显高于其他治疗方法。结论光凝联合玻璃体切除术治疗血管增殖性视网膜肿瘤效果良好,可在临床上应用。关键词:血管增殖性视网膜肿瘤;临床特征;治疗方法;临床疗效
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引用次数: 0
The influence of inferior oblique muscle surgery for eye rotate status 下斜肌手术对眼旋转状态的影响
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.012
Lin Pang, De-Jun Zhu
Objective To investigate the influence of excyclotorsion by inferior oblique (IO) recession versus anterior transposition. Methods A total of 31 cases (48 eyes) with paralysis of superior oblique (SOP) were reported. Recession of IO was performed in 36 eyes with SOP (group A) and anterior transposition of IO was performed in 12 eyes with SOP associated with dissociated vertical deviation (group B). Objective cycloposition was assessed by fundus photograph before and after surgery in all cases. The mean time of follow-up was 6.67 months. Results The fovea-disc angle (FAD) of pre-or post-operation were (14.57°±6.26°) and (9.50°±5.45°), respectively. In group A and group B, that were (10.25°±6.09°) and (5.75°±4.73°) respectively. The excyclotorsion was improved (5.07°±3.92°) and (4.50°±3.67°), respectively in two groups. Conclusions The effect to improve excyclotorsion by inferior oblique recession or anterior transposition is similar. Key words: Recession of IO; Anterior transposition of IO; Cycloduction
目的探讨下斜肌(IO)后退对前转位外旋的影响。方法对31例(48眼)上斜眼麻痹患者进行回顾性分析。A组36只眼行眼内移位术,B组12只眼行眼内移位术,并伴有游离性垂直偏移。所有病例术前、术后均通过眼底照片评估眼内睫状体位置。平均随访时间6.67个月。结果手术前后中央窝-椎间盘角(FAD)分别为(14.57°±6.26°)和(9.50°±5.45°)。A组为(10.25°±6.09°),B组为(5.75°±4.73°)。两组患者的外扭转度分别为(5.07°±3.92°)和(4.50°±3.67°)。结论下斜位后退和前转位对扭转外旋的改善效果相似。关键词:IO衰退;IO前移位;Cycloduction
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引用次数: 0
Observation of superior rectus transposition with posterior intermuscular suture for abducent paralytic strabismus 上直肌转位肌间后缝治疗外展麻痹性斜视的疗效观察
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.013
Jun Yang, Qian Li
Objective To observe the effective of superior rectus transposition with posterior rectus transposition with posterior intermuscular suture for treatment of abducent paralytic strabismus. Methods A retrospection study. Totally 21 cases (21 eyes) of severe esotropia caused by abducent paralysis were treated by superior rectus transposition with posterior intermuscular suture. The cases were collected from April 2014 to December 2015 in our hospital. The position of eye in preoperation, during operation and postoperation were analyzed. Results Treated by superior rectus transposition with posterior intermuscular suture and medial rectus recession, during operation, superior rectus transposition corrected internal oblique 12±3.2o, posterior intermuscular suture of superior rectus and external rectus corrected internal oblique 4.2±1.6o, medial rectus recession 6-8mm, corrected internal oblique 14±4.2o. Esotropia of 21 cases were corrected significantly. Apparent improvement was obtained in paralytic eye. No significant vertical and rotational strabismus was induced. After 6 months to 2 years follow-up, the eye position kept stable and no obvious change occurred. Conclusions Superior rectus transposition with posterior intermuscular suture in treating abducent paralytic strabismus is feasible and its outcome is stable. Key words: Superior rectus transposition; Posterior intermuscular suture; Abducent paralytic strabismus
目的观察上直肌转位联合后直肌转位肌间后缝治疗外展麻痹性斜视的疗效。方法回顾性研究。对21例(21眼)外展麻痹所致严重内斜视采用上直肌转位肌间后缝术治疗。病例于2014年4月至2015年12月在我院收集。分析术前、术中、术后眼的位置。结果采用上直肌转位加后肌间缝合加内直肌后退术治疗,术中上直肌转位矫正内斜12±3.2°,上直肌与外直肌后肌间缝合矫正内斜4.2±1.60°,内直肌后退6 ~ 8mm,矫正内斜14±4.2°。21例内斜视矫正明显。麻痹眼有明显改善。无明显的垂直和旋转斜视。随访6个月~ 2年,眼位保持稳定,无明显变化。结论上直肌转位加肌间后缝治疗外展麻痹性斜视是可行的,疗效稳定。关键词:上直肌移位;后肌间缝合;外展麻痹性斜视
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引用次数: 0
Application of vivo confocal microscopy after Corneal collagen cross link in Keratoconus 角膜胶原交联后体内共聚焦显微镜在圆锥角膜中的应用
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.023
Yuan-jue Zhu, Ming Li
Objective To study the characteristics of vivo confocal microscopy after corneal collagen cross link, and to evaluate the efficacy of corneal collagen cross-linking for keratoconus therapy. Methods A total of 23 keratoconus patients (23 eyes) with corneal thickness no less than 400 μm were recruited in this study. Corneal epithelium of central 9 mm was removed mechanically under topical anesthesia, 0.1% riboflavin was applied. Then standard UVA/riboflavin corneal crosslinking was applied. VA, Slit lamp, anterior segment optical coherence tomography (AS-OCT), vivo confocal microscopy was examined and recorded. Results Imaging characteristics in AS-OCT: Preoperative corneal stroma was relatively uniform yellowish green and reflective, postoperative anterior corneal storma emerges relatively dense yellow and green high reflectance, posterior stroma was relatively loose green-based low reflection. Imaging characteristics in vivo confocal microscopy: Preoperative corneal stroma fibers wrinkles showed low reflective stripes, postoperative corneal storma showed high reflective stripes along the dark stripes, and it was more obvious in the anterior storm than the posterior stroma. Conclusions Vivo confocal microscopy shows clear morphological evidence in CXL. UVA/0.1% riboflavin corneal crosslinking achieve conductive riboflavin penetration, and it is safe and effective in the treatment of keratoconus. Key words: Vivo confocal microscopy; UVA/riboflavin corneal crosslinking; Riboflavin; Corneal thickness; Keratoconus
目的研究角膜胶原交联后体内共聚焦显微镜的特点,评价角膜胶原交联治疗圆锥角膜的疗效。方法选取角膜厚度不小于400 μm的圆锥角膜患者23例(23只眼)。表面麻醉下机械切除角膜中央9 mm上皮,应用0.1%核黄素。然后应用标准UVA/核黄素角膜交联。检查并记录VA、裂隙灯、前段光学相干断层扫描(AS-OCT)、体内共聚焦显微镜。结果AS-OCT影像学特征:术前角膜基质呈相对均匀的黄绿色反射,术后角膜前基质呈相对致密的黄绿色高反射,后基质呈相对疏松的绿色低反射。活体共聚焦显微镜成像特征:术前角膜间质纤维褶皱呈低反射条纹,术后角膜风暴沿暗条纹呈高反射条纹,且风暴前较后间质明显。结论体内共聚焦显微镜显示出明显的CXL形态学证据。UVA/0.1%核黄素角膜交联可实现核黄素导电渗透,治疗圆锥角膜安全有效。关键词:体内共聚焦显微镜;UVA/核黄素角膜交联;核黄素;角膜厚度;圆锥形角膜
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引用次数: 0
Evaluation of the damage of optic nerve after acute primary angle closure glaucoma 急性原发性闭角型青光眼视神经损伤的评价
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.005
Qing Zhang, Hengli Zhang, Guangxian Tang, Min Wang, Dandan Liu, Fan Li, Hua Yu, Li Li
Objective To investigate the changes in thickness of retinal nerve fiber layer (RNFL) and visual fields following the initial acute attack of acute primary angle closure glaucoma (APACG) within 1 year. Methods A prospective cohort study. 30 consecutively recruited patients with APACG were observed (the attacked eye was as the observed eye while the fellow eye as control). At 6 time points (after intraocular pressure controlled for 24 hour, 1 week, 1 month, 3 month, 6 month, 12 month), intraocular pressure (IOP), RNFL thickness and Humphrey perimeter were analyzed. Results Compared with the control group, the average RNFL thickness in the observed group were thicker at 24 hour and 1 week (P 0.05). The thickness of averaged RNFL was positively correlated with the MD (P <0.05). Conclusions The thickness of the RNFL in patients with APACG is diffusely increasing after the acute attack for the first time, which is gradually thinner with the time going. However,it is stable after IOP con-trolled for 6 months; Perimetric damaged is reversible at the 1 month after IOP controlled and there is no deterioration until the 1 year; For the optic nerve, the injury of morphology is consistent with the function. Key words: Acute primary angle-closure glaucoma; Retinal nerve fiber layer; Mean defect; Pattern standard deviation
目的探讨急性原发性闭角型青光眼(APACG)急性发作后1年内视网膜神经纤维层(RNFL)厚度及视野的变化。方法前瞻性队列研究。连续招募30例APACG患者进行观察(发病眼为观察眼,同侧眼为对照)。在眼压控制24小时、1周、1个月、3个月、6个月、12个月后的6个时间点,分析眼压(IOP)、RNFL厚度和Humphrey周长。结果观察组术后24 h、1周RNFL平均厚度较对照组增厚(P < 0.05)。RNFL平均厚度与MD呈正相关(P <0.05)。结论APACG患者首次急性发作后RNFL厚度呈弥漫性增加,随时间延长逐渐变薄。IOP控制6个月后稳定;眼周损伤在IOP控制后1个月是可逆的,直到1年才出现恶化;视神经形态学损伤与功能损伤一致。关键词:急性原发性闭角型青光眼;视网膜神经纤维层;意味着缺陷;模式标准差
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引用次数: 0
Positive relative accommodation increase produced in response to overnight orthokeratology 夜间角膜塑形术产生的正的相对调节增加
Pub Date : 2017-06-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.06.015
Yanchun Xu, F. Gu, Fu-sheng Zhang, Huan-yun Yu, Chun-lei Liu
Objective To observe the changes of accommodation with myopia adolescents after wearing orthokeratology, and to investigate the mechanism of orthokeratology controlling myopia progression. Methods A total of 110 adolescents with myopia, 43 adolescents were emmetropia, 48 patients wore orthokeratology. Phoria at distance and near, positive relative accommodation and negative relative accommodation (PRA/NRA) were measured with phoropter, and compared with the patients wearing frame glasses. The PRA and NRA before and after wearing orthokeratology in 19 patients were compared. Results The PRA after 3 months wearing orthokeratology group (-4.32±1.59)D were much higher than the patients wearing frame glasses (-2.27±1.19)D. There was significant difference in PRA (P<0.05). There was no significant difference in NRA. The PRA after wearing orthokeratology (-4.22±1.67)D were higher than the PRA before wearing orthokeratology (-2.49±1.05) D, there was significant difference (P <0.05). Conclusions The PRA is increased after wearing orthokeratology, the accommodation is increased, and it may be the reasonable mechanism of orthokeratology controlling myopia progression. Key words: Myopia; Orthokeratology; Positive relative accommodation
目的观察青少年近视患者配戴角膜塑形镜后适应能力的变化,探讨角膜塑形镜控制近视进展的机制。方法选取青少年近视110例,远视43例,配戴角膜塑形镜48例。用光镜测量远、近视距、正相对调节和负相对调节(PRA/NRA),并与配戴框架眼镜的患者进行比较。比较19例患者佩戴角膜塑形镜前后的PRA和NRA。结果角膜塑形镜配戴组3个月后PRA(-4.32±1.59)D显著高于框架镜配戴组(-2.27±1.19)D。两组间PRA差异有统计学意义(P<0.05)。两组NRA差异无统计学意义。佩戴角膜塑形镜后PRA(-4.22±1.67)D高于佩戴角膜塑形镜前PRA(-2.49±1.05)D,差异有统计学意义(P <0.05)。结论佩戴角膜塑形镜后PRA增加,调节能力增强,可能是角膜塑形镜控制近视进展的合理机制。关键词:近视;角膜矫正术;正相对调节
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引用次数: 0
Short-term effect of orthokeratology lens to correct myopia in school-age children 角膜塑形镜矫正学龄儿童近视的近期效果
Pub Date : 2017-05-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.05.007
Zhenzhen Tong, Yi Li, Jianmei Feng, Fang Wang, Yan-peng Chen
Objective To observe the effect of OK lens correct and prevent myopia in school-age children. Methods A retrospective case-cohort study of 206 eyes ofschool-age children with myopia received treatment,which were divided into OK lens group 106 eyes and frame lens group of 100 eyes. The changes of UCVA,AL,SE and corneal curvature were analyzed. Results UCVA of OK lens group began to improve after 1day, improved obviously after 1month (P <0.05),1-6months UCVA tended to be stable;SE and corneal curvature decreased after 1day, decreased obviously after 1month (P <0.05). Compared with the frame lens group, the AL and SE increased after 1 day, but the growth rate was slow and the difference was statistically significant(P <0.01). Conclusions The OK lens is effective in correcting the myopia of school-age children, and it has a certain delay effect on the progression of myopia. Key words: Orthokeratology lens; School-age children; Spherical equivalent; Ocular axial length; Corneal curvature
目的观察OK晶状体矫正和预防学龄儿童近视的效果。方法对206例接受治疗的学龄近视儿童进行回顾性病例队列研究,分为OK晶状体组106眼和框架晶状体组100眼。分析UCVA、AL、SE和角膜曲率的变化。结果OK晶状体组UCVA在1天后开始改善,1个月后明显改善(P <0.05),1-6个月UCVA趋于稳定;SE和角膜曲率在1天后下降,1个月后明显下降(P <0.05)。与框架透镜组相比,AL和SE在1 d后升高,但增长速度较慢,差异有统计学意义(P <0.01)。结论OK晶状体矫正学龄儿童近视效果显著,对近视的发展有一定的延缓作用。关键词:角膜塑形镜;学龄儿童;球形等效;眼轴长;角膜曲率
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引用次数: 0
A follow-up study of macular structure and visual function after idiopathic epiretinal membrane surgery 特发性视网膜前膜手术后黄斑结构和视觉功能的随访研究
Pub Date : 2017-05-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.05.010
Zirui Peng, Yong Liu
Objective To investigate the relationship between macularstructure and visual acuity in patients with idiopathic macular membrane surgery. Methods A retrospective trail analyzed the data of 38 patients (38eyes). The best corrected visual acuity(BCVA), central foveal thickness(CFT), average macular thickness were measured and the correlations between BCVA, CFT and average macular thickness were investigated using Pearson correlation analysis. Patients were divided into two groups based on whether the Ellipsoid Zone (EZ) was irregular. The BCVA, CFT and average macular thickness of each group were also analyzed. Results The mean BCVA was improved to0.45 (SD 0.26) and the mean CFT regressed to 334.5um (SD 69.5).The preoperative BCVA was significantly correlated with preoperative average macular thickness and the final BCVA was correlated with final CFT. A linear relationship between the reduction of central foveal thickness and improvement of visual acuity was confirmed. The final BCVA of EZ intact group was better than EZ disrupted group. Conclusions CFT could be a useful prognostic factor after ERM surgery. It might be better to schedule surgery while the EZ remain intact. Key words: Idiopathic epiretinalmembrane; Optical coherence tomography; Visual acuity; Central foveal thickness; Ellipsoid zone
目的探讨特发性黄斑膜手术患者黄斑结构与视力的关系。方法回顾性分析38例患者(38眼)的资料。测定最佳矫正视力(BCVA)、中央凹厚度(CFT)、平均黄斑厚度,采用Pearson相关分析探讨BCVA、CFT与平均黄斑厚度的相关性。根据椭球区(EZ)是否不规则分为两组。分析各组的BCVA、CFT及平均黄斑厚度。结果平均BCVA改善至0.45 (SD 0.26),平均CFT回归至334.5um (SD 69.5)。术前BCVA与术前平均黄斑厚度显著相关,最终BCVA与最终CFT相关。中央中央凹厚度的减少与视力的改善之间存在线性关系。EZ完整组最终BCVA优于EZ破坏组。结论CFT可能是ERM术后一个有用的预后因素。在EZ完好无损的情况下进行手术可能会更好。关键词:特发性视网膜上膜;光学相干层析;视力;中央凹厚度;椭球体区
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引用次数: 0
Structure and function of the visual area forms of idiopathic macular epiretinal membrane surgery 特发性黄斑视网膜前膜手术的视区结构与功能
Pub Date : 2017-05-10 DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.05.011
Li Xu, L. Chang, Cong-hui Li
Objective To compare the structure morphologyand visual function changes of surgery for idiopathic epimacular membrane(IEMM)withand without internal limiting membrane(ILM)peeling,in idiopathic macular membrane patients. Methods Aretrospective analysis wasmade for83 patients (84 eyes)with IEMM,according to different treatments divided into two groups,observation group: EMM peeling combined withILMpeeling;control group:single EMM peeling.Followed up for 2 to 12 months to observe the epimacular membranepeeling,macular edema,visual changes,and changes in visual acuity and foveal thickness for linear correlation analysis. Results Postoperative visual acuity improved significantly on both groups(P <0.05),epiretinal membrane were successfully stripped.Observation group:40 eyes of 40 cases of macular edema had a recurrent(2.5%);control group:43 cases 44 eyes of 5 recurrent macular edema(11.4%).Edema recurrent rate compared to the two groups was statistically significant(P <0.05),postoperative visual acuity improved margin and margin improvement in foveal thickness correlated positively(observation group,r=0.616,P=0.00;control group,r=0.462,P=0.01). Conclusions Vitrectomy combined internal limitingmembrane peeling cansignificantly improve the success rate and reduce the recurrence of edema and improve visual function,improve visual acuity better,changes in vision and central macular thickness with a positive correlation. Key words: Idiopathic macular epiretinal membranes; 23-gaugevitrectomy; Internal limiting membrane peeling; Edema recurrence
目的比较特发性黄斑外膜(IEMM)剥脱和未剥脱的患者手术后的结构形态和视觉功能变化。方法回顾性分析83例(84眼)IEMM患者,根据治疗方法的不同分为两组,观察组:EMM剥离联合ilm剥离;对照组:单一EMM剥离。随访2 ~ 12个月,观察黄斑外膜剥离、黄斑水肿、视力变化,以及视力与中央凹厚度的变化进行线性相关分析。结果两组术后视力明显改善(P <0.05),视网膜前膜剥离成功。观察组:40眼40例黄斑水肿复发一次(2.5%);对照组:43眼44眼5例黄斑水肿复发一次(11.4%)。两组水肿复发率比较,差异均有统计学意义(P <0.05),术后边缘视力改善与边缘中央凹厚度改善呈正相关(观察组,r=0.616,P=0.00;对照组,r=0.462,P=0.01)。结论玻璃体切除术联合内限制膜剥离可显著提高手术成功率,减少水肿复发率,改善视功能,改善视力较好,视力的改变与中央黄斑厚度呈正相关。关键词:特发性黄斑视网膜前膜;23-gaugevitrectomy;内限膜剥离;水肿复发
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引用次数: 0
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