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Antibody-Drug Conjugates and Ocular Toxicity: Nursing, Patient, and Organizational Implications for Care. 抗体药物共轭物与眼部毒性:护理、患者和组织对护理的影响。
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.188-196
Caroline Clark, Ikuko Komo

Background: Antibody-drug conjugates (ADCs) are a novel class of drugs with rapidly expanding oncology indications across solid and hematologic malignancies.

Objectives: This article provides an overview of ADCs with a high risk of ocular reactions and guidance for oncology nurses to help mitigate risk and identify toxicities for prompt management.

Methods: This review presents updated evidence, manufacturer recommendations, and clinical guidance about three ADCs with a risk of overall ocular reactions exceeding 40%, as well as strategies to prepare patients for treatment, prevent reactions, and respond to presenting ocular toxicities.

Findings: ADCs can cause a range of ocular reactions from mild dry eye to severe and dose- limiting corneal adverse reactions and vision loss. Oncology nurses and other members of the interprofessional team can perform focused clinical assessment, provide patient education about self-management and prevention, and coordinate surrounding eye care for patients receiving treatment with ADCs.

背景:抗体药物共轭物(ADCs)是一类新型药物,其肿瘤适应症在实体肿瘤和血液系统恶性肿瘤中迅速扩大:本文概述了眼部反应风险较高的 ADC,并为肿瘤科护士提供指导,帮助她们降低风险并识别毒性,以便及时处理:这篇综述介绍了三种眼部反应总体风险超过40%的ADC的最新证据、制造商建议和临床指导,以及让患者做好治疗准备、预防眼部反应和应对眼部毒性反应的策略:ADC可引起一系列眼部反应,从轻度干眼症到严重的剂量限制性角膜不良反应和视力丧失。肿瘤科护士和跨专业团队的其他成员可以为接受 ADCs 治疗的患者进行重点临床评估,提供自我管理和预防方面的患者教育,并协调周围的眼科护理。
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引用次数: 0
Perianal Injury Prevention in Patients With Leukemia. 预防白血病患者的肛周损伤
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.149-156
Cindy Paredes, Katie Reed, LaTarvia Moore, Jeannine M Brant

Background: Perianal injuries in adults with hematologic malignancies can result in sepsis or death. Patients on a 36-bed acute care oncology unit experienced increased perianal injuries from 2018 to 2021 based on a chart review, which revealed that 24 patients with leukemia, all of whom had received cytarabine, developed perianal injuries.

Objectives: This study examined whether a nurse-led educational intervention would decrease perianal injuries.

Methods: A survey examined baseline nurse knowledge on perianal injuries. Nurses received a 10-minute in-service education session about perianal injuries, their predisposing factors, and prevention strategies followed by a survey to test their knowledge. Twenty nurses completed the pre- and postintervention surveys.

Findings: After the intervention, staff knowledge increased by 33%. One year postintervention, perianal injuries had decreased by more than 50%. Nurse and patient education are vital to decrease perianal injuries in patients with leukemia.

背景:成人血液系统恶性肿瘤患者的肛周损伤可导致败血症或死亡。2018年至2021年,一个拥有36张病床的急诊肿瘤科的患者肛周损伤增加,根据病历回顾,24名白血病患者出现了肛周损伤,这些患者均接受过阿糖胞苷治疗:本研究探讨了护士主导的教育干预能否减少肛周损伤:方法:通过调查了解护士对肛周损伤的基本认识。护士们接受了 10 分钟的在职教育课程,内容涉及肛周损伤、其诱发因素和预防策略,随后进行了一项调查以测试她们的知识水平。20 名护士完成了干预前后的调查:干预后,员工的知识水平提高了 33%。干预一年后,肛周损伤减少了 50%以上。护士和患者教育对减少白血病患者肛周损伤至关重要。
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引用次数: 0
Systematic Review of Malnutrition Risk Factors to Identify Nutritionally At-Risk Patients With Head and Neck Cancer. 系统回顾营养不良风险因素,识别营养高危的头颈癌患者。
IF 1.3 4区 医学 Q3 NURSING Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.197-208
Pengpeng Wang, Kim Lam Soh, Kim Geok Soh, Li Xue, Chuanyi Ning, Yanmei Tan, Xueling Huang

Background: Patients with head and neck cancer are prone to malnutrition, which can lead to adverse health outcomes. A review of the literature revealed a lack of systematic reviews addressing risk factors for malnutrition in this population.

Objectives: This study aimed to fill the knowledge gap by identifying risk factors for malnutrition in patients with head and neck cancer.

Methods: A comprehensive search was conducted in PubMed®, Web of Science, Embase®, and Cochrane Library databases, spanning from their inception until June 2023. Three researchers critically evaluated the inclusion and exclusion criteria. Two investigators independently screened the literature and extracted data, resolving any discrepancies through consensus.

Findings: This systematic review includes 18 studies. The results indicated that risk factors for malnutrition in patients with head and neck cancer encompass disease-related, genetic, lifestyle, nutritional health, physiologic, psychological, and treatment-related factors.

背景:头颈部癌症患者容易出现营养不良,从而导致不良的健康后果。文献综述显示,缺乏针对该人群营养不良风险因素的系统性综述:本研究旨在通过确定头颈部癌症患者营养不良的风险因素来填补知识空白:在 PubMed®、Web of Science、Embase® 和 Cochrane Library 数据库中进行了全面检索,时间跨度从开始到 2023 年 6 月。三名研究人员严格评估了纳入和排除标准。两名研究人员独立筛选文献并提取数据,通过共识解决任何差异:本系统综述包括 18 项研究。结果表明,头颈部癌症患者营养不良的风险因素包括疾病相关因素、遗传因素、生活方式因素、营养健康因素、生理因素、心理因素和治疗相关因素。
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引用次数: 0
Prevention, Surveillance, and Treatment of Breast Cancer-Related Lymphedema: The Role of the Advanced Practice Provider. 乳腺癌相关淋巴水肿的预防、监测和治疗:高级医疗服务提供者的作用》。
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.122-127
Leslie A McGrath, Emily Bloomfield

Breast cancer-related lymphedema is a lifelong disease associated with decreased quality of life and increased healthcare costs. Evidence supports early detection and prompt treatment through prospective surveillance models.

乳腺癌相关淋巴水肿是一种终身性疾病,与生活质量下降和医疗费用增加有关。有证据支持通过前瞻性监测模型进行早期检测和及时治疗。
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引用次数: 0
Two Case Reports on Financial Toxicity and Healthcare Transitions in Adolescent and Young Adult Cancer Survivors. 关于青少年和年轻成人癌症幸存者的经济毒性和医疗过渡的两个案例报告。
IF 1.3 4区 医学 Q3 NURSING Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.227-231
Jean Edward, Katie Anne Brown, Mackenzie Caldwell, Elizabeth Ann Ruschman, Haafsah Fariduddin, Kimberly D Northrip, John A D'Orazio

A team conducted semistructured interviews and developed case reports about financial toxicity (FT) and healthcare transitions (HCTs) with two adolescent and young adult (AYA) cancer survivors. These reports found poor HCTs f.

一个研究小组对两名青少年癌症幸存者进行了半结构化访谈,并编写了有关财务毒性(FT)和医疗保健过渡(HCT)的案例报告。这些报告发现 HCTs 的效果不佳。
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引用次数: 0
Targeted Drug Therapies: Beyond Blood Counts and Chemistries. 靶向药物疗法:超越血细胞计数和化学指标。
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.215-219
Solomea Asfaw, Samantha Matys, Benyam Muluneh

Although the field of oncology pharmacotherapy has progressed rapidly with the introduction of novel targeted therapies, there are many unintended side effects that require knowledge of laboratory monitoring for appropriate m.

尽管随着新型靶向疗法的推出,肿瘤药物治疗领域取得了飞速发展,但仍存在许多意外副作用,需要掌握实验室监测知识,才能对症下药。
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引用次数: 0
Oncology Nursing Society's Genomics and Precision Oncology Learning Library Resources for Nursing Practice. 肿瘤护理学会基因组学和精准肿瘤学学习图书馆护理实践资源。
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.133-141
Erin Dickman, Mary L Schmitt, Kerensa Marty, Suzanne M Mahon

Oncology nurses need an understanding of genomic science to provide optimal care, yet they may have limited background in how this science guides treatment. The Oncology Nursing Society (ONS) responded to this identified need.

肿瘤科护士需要了解基因组科学以提供最佳护理,但她们对这一科学如何指导治疗的背景知识可能有限。肿瘤护理学会(ONS)对这一需求做出了回应。
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引用次数: 0
Prelicensure Nursing Students' Attitudes Toward Patients With Cancer Revisited. 重新审视执业前护理专业学生对癌症患者的态度。
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.220-226
Tracy A Ruegg, Kawther Hamash, Sherry A Burrell

Recruiting graduate nurses into oncology practice postgraduation continues to be challenging. Graduate nurses tend to prefer clinical settings that they consider high-tech or challenging, with oncology ranking low. In additio.

招聘毕业护士在毕业后从事肿瘤工作仍然是一项挑战。毕业护士倾向于选择他们认为高科技或具有挑战性的临床环境,而肿瘤学则排名靠后。此外
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引用次数: 0
Using Acuity to Predict Oncology Infusion Center Daily Nurse Staffing and Outcomes. 利用急性期预测肿瘤输液中心的日常护士配备和结果。
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.181-187
Pamela F Tobias, Zachary Oliver, Yue Huang, Christopher Bayne, Lisa Fidyk

Background: Outpatient oncology infusion centers (OICs) use acuity to quantify the complexity and intensity of care to improve staffing levels and equitable patient assignments. OIC interviews revealed inconsistent measurement of acuity and a mixture of use cases. No publications measured objective operational benefits beyond surveyed nurse satisfaction or compared different models of acuity.

Objectives: This study assessed three acuity models across multiple centers to determine whether acuity was superior to patient volumes or patient hours in predicting the number of nurses needed to care for scheduled patients in an OIC, as well as the effect on objective metrics of missed nurse lunch breaks and patient wait times. A secondary end point was used to identify a superior model.

Methods: Classification machine learning models were built to assess the predictive value of three acuity models compared to patient hours and patient visits.

Findings: None of the tested acuity models were found to have statistically significant improvement to the prediction of needed OIC nurse staffing, patient wait times, or missed nurse lunch breaks.

背景:门诊肿瘤输液中心(OICs)使用急性程度来量化护理的复杂性和强度,以提高人员配备水平和病人分配的公平性。对门诊肿瘤输液中心的访谈显示,对严重程度的测量并不一致,使用情况也多种多样。除调查护士满意度外,没有出版物对客观的运营效益进行衡量,也没有对不同的敏锐度模型进行比较:本研究评估了多个中心的三种严重程度模型,以确定严重程度是否优于病人数量或病人小时数,从而预测在 OIC 中护理排班病人所需的护士人数,以及对护士错过午休时间和病人等待时间等客观指标的影响。方法:建立分类机器学习模型来评估护士对病人的护理情况:方法:建立分类机器学习模型,以评估三种敏锐度模型与患者就诊时间和就诊人次相比的预测价值:结果:没有发现任何一个经过测试的严重程度模型在预测所需的 OIC 护士人员配备、病人等待时间或错过的护士午休时间方面有明显的统计学改进。
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引用次数: 0
How Can a Global Experience Enkindle a Passion for Oncology Nursing? 全球体验如何激发对肿瘤护理的热情?
IF 1.1 4区 医学 Q3 Nursing Pub Date : 2024-03-15 DOI: 10.1188/24.CJON.232
Jingwen Zhang

I have had a broad global life experience. I was born in China and at the age of 11 years, my family decided that going to live with relatives in the United States was the best thing for me. I had to learn a new culture and l.

我拥有广泛的全球生活经历。我出生在中国,11 岁那年,家人决定让我到美国的亲戚家生活,这对我来说是最好的选择。我必须学习新的文化和生活方式。
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期刊
Clinical journal of oncology nursing
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