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Effects and safety of the traditional Chinese exercise baduanjin on depression and anxiety in COVID-19 patients: A systematic review and meta-analysis 中国传统运动八段锦对 COVID-19 患者抑郁和焦虑的影响及安全性:系统回顾与荟萃分析
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-30 DOI: 10.1016/j.ctim.2024.103094
Yan Huang , Xiao Xu , Bishal Kumar Chaurasiya , Prudence Bizimana , Mei-Juan Qian , Epipode Ntawuyamara
<div><h3>Aim</h3><div>This systematic review and meta-analysis aimed to assess the safety and efficacy of Baduanjin, a traditional Chinese exercise (TCM), for reducing depression and anxiety in individuals suffering from coronavirus disease 2019 (COVID-19).</div></div><div><h3>Methods</h3><div>Nineteen databases were searched from their inception through August 2024 to gather data for this study. The focus of this study was randomized controlled trials (RCTs) in which Baduanjin was administered for the treatment of COVID-19 patients with depression and anxiety. The study included various types of Baduanjin exercise, whether used alone or in conjunction with other treatment modalities, for the control group. The comparators included a waitlist control, usual care, health education and supportive counseling, psychosocial support therapy, pharmacotherapies, and other common exercises. The exclusion criteria for trials were trials comparing different treatment durations, different treatment frequencies, and different types of Baduanjin exercise. Moreover, other traditional Chinese medicine (TCM) therapeutic methods applied in either the intervention or control group were also excluded. Throughout the entire study, the selection process, data extraction and quantitative analysis were carried out in strict adherence to all relevant guidelines. The Cochrane criteria for risk of bias were used to assess the methodological quality of the trials. In our review, a meta-analysis was performed using the software STATA MP14.</div></div><div><h3>Results</h3><div>After conducting a meta-analysis, eight RCTs were found to have satisfied the inclusion criteria. The effects of Baduanjin exercise on self-rating anxiety scale (SAS) scores were investigated in five RCTs comprising a total of 228 patients. Analysis of the results revealed that the combination of Baduanjin exercises and conventional therapies led to a statistically significant reduction in SAS scores [MD=-3.21 (95 % CI= −3.64, −2.79), <em>P</em>< 0.001] compared to conventional therapies alone. Moreover, this systematic review explored the effect of Baduanjin exercise on self-rating depression scale (SDS) scores (three RCTs involving 83 participants), Hamilton Anxiety Rating Scale (HAM-A) scores (one RCT involving 103 participants), Patient Health Questionnaire (PHQ-9) scores (one RCT involving 70 participants) and Generalized Anxiety Disorder-7 (GAD-7) scores (one RCT involving 59 participants) for patients with COVID-19. The results showed that, in addition to conventional therapies, Baduanjin exercise had a more favorable impact on reducing the SDS score [mean difference (MD) =-2.86 (95 % CI=4.11, −1.61), <em>P</em>=0.025], <em>P</em>HQ-9 score [MD=-5.31, 95 % CI=-8.73, −1.89), <em>P</em>=0.002] and HAM-A score [MD=-3.00, 95 % CI=-5.33, −0.67], <em>P</em>=0.010] in patients with COVID-19 than did the use of conventional therapies alone. Furthermore, the combination of Baduanjin exercise and conven
目的本系统综述和荟萃分析旨在评估八段锦(一种传统中药)对减轻2019年冠状病毒病(COVID-19)患者抑郁和焦虑的安全性和有效性。方法为了收集本研究的数据,检索了19个从开始到2024年8月的数据库。本研究的重点是使用巴杜安金治疗 COVID-19 抑郁症和焦虑症患者的随机对照试验(RCT)。研究包括各种类型的八段锦锻炼,无论是单独使用还是与其他治疗方式结合使用,对照组均为八段锦锻炼。比较组包括候补对照组、常规护理组、健康教育和支持性咨询组、社会心理支持疗法组、药物疗法组和其他常见运动组。排除试验的标准是比较不同的治疗时间、不同的治疗频率和不同类型的八段锦运动。此外,在干预组或对照组中应用的其他传统中医治疗方法也被排除在外。在整个研究过程中,选择过程、数据提取和定量分析都严格遵守了所有相关准则。在评估试验的方法学质量时,采用了 Cochrane 的偏倚风险标准。在我们的综述中,使用 STATA MP14 软件进行了荟萃分析。结果在进行荟萃分析后,发现有 8 项研究符合纳入标准。五项研究共纳入 228 名患者,研究了八段锦运动对焦虑自评量表(SAS)评分的影响。结果分析表明,与单独使用传统疗法相比,八段锦运动与传统疗法相结合可使 SAS 评分显著降低[MD=-3.21 (95 % CI= -3.64, -2.79),P< 0.001]。此外,本系统综述还探讨了八段锦运动对 COVID-19 患者的抑郁自评量表(SDS)评分(3 项研究,83 人参与)、汉密尔顿焦虑评分量表(HAM-A)评分(1 项研究,103 人参与)、患者健康问卷(PHQ-9)评分(1 项研究,70 人参与)和广泛性焦虑症-7(GAD-7)评分(1 项研究,59 人参与)的影响。结果显示,除常规疗法外,八段锦运动对降低 SDS 评分[平均差(MD)=-2.86(95 % CI=4.11,-1.61),P=0.025]、PHQ-9 评分[MD=-5.31,95 % CI=-8.73,-1.89),P=0.002]和 HAM-A 评分[MD=-3.00,95 % CI=-5.33,-0.67],P=0.010]。此外,与单独使用常规疗法相比,将八段锦运动与常规疗法相结合可有效减少根据 GAD-7 评分出现严重或中度焦虑的患者人数[相对风险(RR)=0.03,95 % CI=0.00,0.51];P=0.020]。然而,所纳入的临床试验缺乏对随机化过程的详细描述,只有一小部分研究报告了适当的分配隐藏程序,这可能会带来选择偏倚。此外,由于八段锦运动的性质,很难对参与者和练习者进行盲法操作,这可能会导致表现偏差。此外,缺乏盲法可能导致评估者主观影响结果,从而造成检测偏差。结论 由于现有的 RCT 存在较高的偏倚风险,因此很难就八段锦运动是否是减少 COVID-19 患者抑郁和焦虑的有效干预措施得出确切结论。有必要进一步开展严格的 RCT 研究,但需要克服现有证据在方法上的不足。
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引用次数: 0
Music therapy in hemodialysis patients: Systematic review and meta-analysis 血液透析患者的音乐治疗:系统回顾与元分析》。
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-28 DOI: 10.1016/j.ctim.2024.103090
Feng Lin , Long Chen , Yin Gao

Background

Patients undergoing hemodialysis (HD) face significant challenges; however, non-pharmaceutical interventions hold potential for enhancing their quality of life. This paper evaluates the effects of music therapy on various mental and physiological outcomes in patients undergoing HD.

Methods

This systematic review and meta-analysis followed the PRISMA 2020 guidelines. A comprehensive database search conducted up to May 21, 2024, identified studies for inclusion based on PICOS criteria. The methodological quality of these studies was assessed using the Cochrane risk-of-bias tool and Review Manager 5.4. For the meta-analysis, R and Stata/SE 15.1 were used, applying a random-effects model in cases of significant heterogeneity, and a fixed-effects model when heterogeneity was minimal.

Results

Twenty-four studies involving 1703 participants were analyzed. Music therapy significantly decreased anxiety (SMD: −0.72, 95 % CI: −0.97 to −0.46, I²: 83 %), pain (SMD: −1.22, 95 % CI: −1.68 to −0.75, I²: 93 %), depression (SMD: −0.85, 95 % CI: −1.31 to −0.39, I²: 77 %), stress (SMD: −0.93, 95 % CI: −1.17 to −0.68, I²: 41 %), and adverse reactions associated with HD (SMD: −0.67, 95 % CI: −0.88 to −0.46, I²: 0 %), all showing strong effect sizes (p < 0.001 for all). However, no significant changes were observed in sleep quality, fatigue, satisfaction with HD, systolic or diastolic blood pressure, heart rate, or finger temperature. A slight reduction in respiration rate (p = 0.0072) and an increase in oxygen saturation (p = 0.0056) were noted. While music therapy showed promising results, the notable heterogeneity in pain and anxiety outcomes suggests careful interpretation, although no significant publication bias was detected.

Conclusion

Music therapy has demonstrated encouraging outcomes in improving the well-being of patients undergoing HD, particularly in reducing anxiety, pain, and stress. However, due to notable heterogeneity and methodological issues such as small sample sizes and inconsistent blinding, further high-quality research is needed to confirm these findings and establish more robust evidence.
背景:接受血液透析(HD)的患者面临着巨大的挑战;然而,非药物干预措施有可能提高他们的生活质量。本文评估了音乐疗法对血液透析患者各种心理和生理结果的影响:本系统综述和荟萃分析遵循 PRISMA 2020 指南。截至 2024 年 5 月 21 日的全面数据库检索根据 PICOS 标准确定了纳入的研究。使用 Cochrane 偏倚风险工具和 Review Manager 5.4 对这些研究的方法学质量进行了评估。荟萃分析使用 R 和 Stata/SE 15.1,在异质性显著的情况下使用随机效应模型,在异质性极小的情况下使用固定效应模型:共分析了 24 项研究,涉及 1 703 名参与者。音乐疗法明显减轻了焦虑(SMD:-0.72,95% CI:-0.97 至 -0.46,I²:83%)、疼痛(SMD:-1.22,95% CI:-1.68 至 -0.75,I²:93%)、抑郁(SMD:-0.85,95% CI:-1.31 至 -0.39,I²:77%)。39,I²:77%)、压力(SMD:-0.93,95% CI:-1.17 至 -0.68,I²:41%)和与 HD 相关的不良反应(SMD:-0.67,95% CI:-0.88 至 -0.46,I²:0%),均显示出很强的效应大小(所有效应大小的 p <0.001)。然而,在睡眠质量、疲劳程度、对 HD 的满意度、收缩压或舒张压、心率或指温方面均未观察到明显变化。呼吸频率略有降低(p = 0.0072),血氧饱和度有所提高(p = 0.0056)。虽然音乐疗法显示出了令人鼓舞的结果,但疼痛和焦虑结果的显著异质性表明,尽管没有发现明显的出版偏倚,但仍需谨慎解释:音乐疗法在改善接受 HD 治疗的患者的身心健康方面取得了令人鼓舞的成果,尤其是在减轻焦虑、疼痛和压力方面。然而,由于存在明显的异质性以及小样本量和盲法不一致等方法学问题,需要进一步开展高质量的研究来证实这些发现,并建立更有力的证据。
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引用次数: 0
Research trends and hotspots of acupuncture therapy for obesity from 2004 to 2023: A bibliometric analysis 2004 至 2023 年针灸治疗肥胖症的研究趋势和热点:文献计量分析
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-26 DOI: 10.1016/j.ctim.2024.103092
Jinkun Wang , Kangdi Cao , Zhaoyi Chen , Tianli Lyu , Qiuyu Xia , Lu Liu , Bin Li

Background

Acupuncture has been increasingly used in obese people, yet no bibliometric analysis of acupuncture studies for obesity exists. This bibliometric study analyzed research trends, cooperation, and knowledge dissemination on acupuncture for obesity over the past 20 years to inform future directions.

Objectives

To investigate the characteristics, hotspots, and frontiers of global scientific output in acupuncture research for obesity over the past two decades.

Methods

We retrieved publications on acupuncture for obesity published from 2004 to 2023 from the Web of Science Core Collection. Using Citespace, VOSviewer, and Bibliometrix, we analyzed and visualized the publications, countries, institutions, authors, journals, and keywords from various angles.

Results

A total of 357 articles were retrieved. The results showed that the number of annual publications on acupuncture for obesity has increased over time. China had the most publications (217 articles, 60.87 %), with Chengdu University of Traditional Chinese Medicine (24 articles, 6.72 %) as the most prolific institution. Ergene Neyhan, Huang Wei, and Zhou Zhongyu were the most productive authors (9 articles), and the article published by Cho SH in 2009 was the most cited article (60 citations). The most published journal was Evidence-based Complementary and Alternative Medicine, while the Journal of American Journal of Chinese Medicine was the most frequently cited. Recently, “electroacupuncture” “insulin resistance” and “systematic review” appeared frequently. The research hotspots and trends of acupuncture for obesity mainly focus on interventions, hotspot diseases, and mechanism exploration. According to keyword analysis, randomized controlled trials of catgut embedding and mechanistic studies of gut flora are the trends for future research.

Conclusion

Although China is the leading producer, multinational co-operation still needs to be strengthened. Currently, the main interventions for obesity were acupuncture and electroacupuncture, and the hot diseases were obesity combined with polycystic ovary syndrome and metabolic syndrome. In addition, randomised controlled trials of catgut embedding and mechanistic studies of gut flora may be potential directions for future research in the field of acupuncture for obesity.
背景针灸在肥胖症患者中的应用越来越广泛,但目前还没有针灸治疗肥胖症研究的文献计量分析。这项文献计量学研究分析了过去20年针灸治疗肥胖症的研究趋势、合作和知识传播情况,为未来的研究方向提供了参考。方法我们从科学网核心数据库中检索了2004年至2023年发表的有关针灸治疗肥胖症的论文。结果共检索到 357 篇文章。结果表明,随着时间的推移,针灸治疗肥胖症的年度出版物数量有所增加。中国发表的文章最多(217 篇,占 60.87%),其中成都中医药大学发表的文章最多(24 篇,占 6.72%)。Ergene Neyhan、Huang Wei 和 Zhou Zhongyu 是发表文章最多的作者(9 篇文章),Cho SH 于 2009 年发表的文章是被引用次数最多的文章(60 次引用)。发表文章最多的期刊是《循证补充与替代医学》,而《美国中医药杂志》则是被引用次数最多的期刊。最近,"电针"、"胰岛素抵抗 "和 "系统综述 "频繁出现。针灸治疗肥胖的研究热点和趋势主要集中在干预措施、热点疾病、机制探索等方面。根据关键词分析,猫肠埋线的随机对照试验和肠道菌群的机理研究是未来研究的趋势。目前,肥胖症的主要干预手段是针灸和电针,热点疾病是肥胖合并多囊卵巢综合征和代谢综合征。此外,猫肠埋线的随机对照试验和肠道菌群的机理研究可能是针灸治疗肥胖症领域未来研究的潜在方向。
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引用次数: 0
Effects of acupuncture combined with five-element music for people with mild/moderate post-stroke depression: A randomized controlled trial 针灸结合五行音乐对轻度/中度卒中后抑郁症患者的疗效:随机对照试验
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-25 DOI: 10.1016/j.ctim.2024.103088
Jinglong Sun , Xia Zhou , Binbin Ren , Youhua Guo , Qifeng Xu , Qin Wang , Ziyun Feng , Qingqing Jia , Wenwen Li , Li Li , Shouqiang Chen

Objectives

To evaluate the efficacy and safety of acupuncture combined with five-element music (FEM) as an therapeutic strategy for the physical and mental state of Post-stroke depression patients.

Design and setting

Multicenter, randomized clinical trial conducted at 3 hospitals in China and enrolling 237 patients with PSD between June 2019 and April 2021. Participants mild/moderate PSD (17-item GRID Hamilton Depression Scale (HAMD) score 7–24) were randomly assigned (1:1) to acupuncture combined with FEM (AFEM) group or cognitive behavioral therapy (CBT) group.

Main outcome measures

The primary outcome was change and differences between the groups in HAMD-17 from baseline to week 12. Secondary outcomes included Fugl-Meyer Assessment Scale score and Stroke-Specific Quality of Life Scale (SS-QOL) score.

Results

The 237 patients in this intention-to-treat analysis were randomized into either the AFEM group (n=119) or the cognitive behavioral therapy (CBT) group (n=118). Of these 237 participants, 225 (94.9 %) completed all outcome measurements at week 12. The AFEM and CBT groups both showed significant improvement in HAMD-17 from baseline to week 12. Patients in the AFEM group had significantly lower HAMD-17 scores of −3.56 at week 8 (95 % CI,-4.59 to −2.53; p <.001) and −3.50 at week 12 (95 % CI,-4.53 to −2.46; p<.001) than patients in the CBT group. The SS-QOL score improved significantly at week 12. The Fugl-Meyer score was significantly lower in the AFEM group than in the CBT group at week 4, but this difference was not statistically significant upon follow-up at weeks 8 and 12. The incidence of treatment-related adverse events was 2.1 % in the AFEM group, with no serious adverse events reported.

Conclusions

The results suggest that acupuncture and five-element music significantly improve the depressive symptoms in this cohort of Chinese PSD patients, and the toxicities were similar with CBP group.

Registration

This study registered with the ClinicalTrials.gov Identifier: ChiCTR1900023741.
目的评估针灸结合五行音乐(FEM)作为中风后抑郁症患者身心状态治疗策略的有效性和安全性:2019年6月至2021年4月期间,在中国3家医院开展多中心随机临床试验,共招募237名PSD患者。轻度/中度PSD患者(17项GRID汉密尔顿抑郁量表(HAMD)评分7-24分)被随机分配(1:1)至针灸联合FEM(AFEM)组或认知行为疗法(CBT)组:主要结果:HAMD-17从基线到第12周的变化和组间差异为主要结果。次要结果包括Fugl-Meyer评估量表评分和卒中生活质量量表(SS-QOL)评分:在这项意向治疗分析中,237 名患者被随机分配到 AFEM 组(119 人)或认知行为疗法 (CBT) 组(118 人)。在这237名参与者中,有225人(94.9%)在第12周时完成了所有结果测量。从基线到第 12 周,AFEM 组和 CBT 组的 HAMD-17 均有显著改善。在第8周时,AFEM组患者的HAMD-17得分明显降低,为-3.56(95% CI,-4.59至-2.53;P 结论:结果表明,针灸和五行疗法能有效改善患者的HAMD-17得分:结果表明,针灸和五行音乐能明显改善中国PSD患者的抑郁症状,其毒性反应与CBP组相似:本研究已在ClinicalTrials.gov注册:ChiCTR1900023741。
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引用次数: 0
Beyond the spice: The multifaceted role of curcumin in multiple sclerosis management 香料之外:姜黄素在多发性硬化症治疗中的多方面作用
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-25 DOI: 10.1016/j.ctim.2024.103091
Amirhossein Sahebkar, Sepideh Salehabadi, Tannaz Jamialahmadi
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引用次数: 0
Letter to Editor regarding: "The influence of traditional Thai massage on recovery from gastrocnemius muscle fatigue: A single-blind randomised controlled trial". 致编辑的信,内容涉及"传统泰式按摩对腓肠肌疲劳恢复的影响:单盲随机对照试验"。
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-25 DOI: 10.1016/j.ctim.2024.103082
T Triwiyanto, I Putu Alit Pawana, Sari Luthfiyah
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引用次数: 0
Tai Chi for balance and postural control in people with peripheral neuropathy: A scoping review 太极促进周围神经病变患者的平衡和姿势控制:范围综述
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-24 DOI: 10.1016/j.ctim.2024.103089
Mingxiao Yang , Carrie Shao , Cassie Shao , Kirin Saint , Peter M. Wayne , Ting Bao

Background

Peripheral neuropathy can affect balance and increase fall risk. Tai Chi is known to activate neuromuscular systems and may help improve balance and postural control. We conducted a scoping review of clinical studies that evaluated the impact of Tai Chi on balance and related neurobiological outcomes among individuals with peripheral neuropathy.

Methods

We systematically searched three databases from inception to December 19, 2023 and identified 11 eligible clinical studies. We extracted trial information from each study and performed a qualitative study features analysis to summarize the clinical evidence and neurobiological mechanisms of Tai Chi in regulating balance among people with peripheral neuropathy.

Results

We found that among 508 participants with clinical peripheral neuropathy, Tai Chi significantly improved single leg stance, 6-min walk, timed up-and-go tests, and gait speed when measured pre- and post-exercise. However, the differences between Tai Chi and sham exercise control that involved active calisthenics and stretching exercises were not statistically significant. Studies that used quantitative sensory testing showed that Tai Chi was associated with significant increases in plantar vibration and tactile sensitivity. The effect of Tai Chi on postural control varied depending on plantar sensory loss status, and results on muscle strength remained mixed. Other neurobiological effects involve strengthening muscle performance and proprioception and consolidating cognitive awareness of walking strategy and practical behavioral techniques.

Conclusions

The findings indicated that Tai Chi may enhance balance, postural control, and gait speed in patients with peripheral neuropathy, possibly through sensory restoration, although further research is needed to confirm this. Whether Tai Chi improves muscle strength or other gait health parameters is inconclusive. Rigorous randomized clinical trials should be conducted to determine the effect of Tai Chi on balance in this population by measuring functional balance and quantitative sensory outcomes.
背景周围神经病变会影响平衡并增加跌倒风险。太极拳可激活神经肌肉系统,有助于改善平衡和姿势控制。我们对评估太极拳对周围神经病变患者的平衡能力和相关神经生物学结果的影响的临床研究进行了一次范围界定综述。结果我们发现,在 508 名患有临床周围神经病变的参与者中,太极拳能显著改善运动前后的单腿站立、6 分钟步行、定时上下楼测试和步速。然而,太极拳与假运动对照组(包括主动健身操和伸展运动)之间的差异在统计学上并不明显。使用定量感觉测试的研究表明,太极拳与足底振动和触觉灵敏度的显著提高有关。太极拳对姿势控制的影响因足底感觉缺失状况而异,对肌肉力量的影响结果不一。结论研究结果表明,太极拳可增强周围神经病变患者的平衡能力、姿势控制能力和步速,这可能是通过感觉恢复实现的,但还需要进一步的研究来证实。太极拳是否能改善肌肉力量或其他步态健康参数尚无定论。应进行严格的随机临床试验,通过测量功能性平衡和定量感官结果来确定太极拳对这一人群平衡能力的影响。
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引用次数: 0
Effects of chia (Salvia hispanica. L) on anthropometric measures and other cardiometabolic risk factors: A systematic review and dose-response meta-analysis 奇异果(salvia hispanica. L)对人体测量指标和其他心脏代谢风险因素的影响:系统综述和剂量反应荟萃分析。
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-17 DOI: 10.1016/j.ctim.2024.103086
Sevil Kiani , Sina Naghshi , Maryam Saghafi-Asl

Background

Findings of available randomized controlled trials (RCTs) on the effects of chia are inconsistent. Although previous meta-analyses summarized available findings in this regard, some limitations may distort their findings. Moreover, none of these meta-analyses examined the dose-response association of chia on cardiometabolic risk factors (CMRFs). Therefore, the present study aimed to evaluate the effect of chia consumption on CMRFs.

Methods

Relevant RCTs were included by searching the ISI Web of Science, PubMed, and Scopus databases up to June 2, 2023. Mean differences (MD) and 95 % confidence intervals (CI) were pooled using random-effects model.

Results

Ten publications were included in this systematic review and the meta-analysis. The results showed a significant reduction in systolic blood pressure (SBP) (MD = -7.87 mmHg; 95 % CI: − 12.92 to − 2.82; I2 = 71.3 %, P heterogeneity = 0.004), diastolic blood pressure (MD = -6.33 mmHg; 95 %CI: − 7.33 to − 5.34, I2 = 0 %, P heterogeneity = 0.42) and high-density lipoprotein cholesterol (HDL-c) (MD = -4.09 mg/dl; 95 %CI: − 6.76 to − 1.43, I2 = 12.4 %, P heterogeneity = 0.33). However, the effects of chia on the other risk factors were not significant. Based on the dose-response analysis, a 10-g/d increase in chia consumption significantly reduced SBP (MD = -2.20 mmHg; 95 %CI: − 3.75 to − 0.66, I2 = 78.9 %, P heterogeneity < 0.001) and HDL-c (MD = -1.10 mg/dl; 95 %CI: − 1.72 to − 0.49, I2 = 0 %, P heterogeneity = 0.52).

Conclusion

Chia consumption might have a beneficial effect on lowering blood pressure. Chia consumption can also lead to a slight reduction in HDL-c levels. As the quality of the included studies was mostly low, the findings should be interpreted with caution. Well-designed trials with larger sample sizes and longer duration of follow-up are needed to provide additional insight into the dose-dependent effects of chia consumption.
背景:现有的随机对照试验(RCT)对奇异果功效的研究结果并不一致。尽管以前的荟萃分析总结了这方面的现有研究结果,但一些局限性可能会扭曲研究结果。此外,这些荟萃分析都没有研究奇异果对心脏代谢风险因素(CMRFs)的剂量反应关系。因此,本研究旨在评估食用奇异果对 CMRFs 的影响:方法:通过检索 ISI Web of Science、PubMed 和 Scopus 数据库,纳入截至 2023 年 6 月 2 日的相关 RCT。采用随机效应模型对平均差(MD)和95%置信区间(CI)进行汇总:本系统综述和荟萃分析共纳入了 10 篇文献。结果显示,收缩压(SBP)(MD=-7.87mmHg;95% CI:-12.92 至-2.82;I2 =71.3%,P 异质性 =0.004)、舒张压(MD=-6.33mmHg;95%CI:-7.33至-5.34,I2=0%,P异质性=0.42)和高密度脂蛋白胆固醇(HDL-c)(MD=-4.09mg/dl;95%CI:-6.76至-1.43,I2=12.4%,P异质性=0.33)。然而,奇异果对其他风险因素的影响并不显著。根据剂量-反应分析,每增加10克/天的奇异果摄入量可显著降低SBP(MD=-2.20毫米汞柱;95%CI:-3.75至-0.66,I2=78.9%,P异质性2=0%,P异质性=0.52):结论:食用奇异果可能对降低血压有益。结论:食用奇异果可能对降低血压有益,也会导致高密度脂蛋白-c水平略有下降。由于纳入研究的质量大多较低,因此应谨慎解释研究结果。要进一步了解食用奇异果的剂量依赖效应,还需要进行设计合理、样本量更大、随访时间更长的试验。
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引用次数: 0
Efficacy and safety of acupuncture for the treatment of insomnia in breast cancer patients: A systematic review and meta-analysis 针灸治疗乳腺癌患者失眠症的有效性和安全性:系统回顾和荟萃分析。
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-17 DOI: 10.1016/j.ctim.2024.103087
Yupeng Weng , Xuanrong Ren , Zheyan Zu , Lu Xiao , Min Chen

Background

Breast cancer-related insomnia is one of the most common symptoms in patients with breast cancer, and acupuncture has been increasingly used in the treatment. However, there has been no meta-analysis that specifically explores the efficacy and safety of acupuncture in treating insomnia related to breast cancer.

Objective

The aim of this review was to systematically analyze the existing literature through a meta-analysis to evaluate the effectiveness and safety of acupuncture for breast cancer-related insomnia.

Methods

Six medical databases were comprehensively searched for previous randomized controlled trials (RCTs) up to April 2024. The Pittsburgh Sleep Quality Index (PSQI) score was the primary outcome. The secondary outcomes include the Insomnia Severity Index (ISI), Sleep Onset Latency (SOL), Wake After Sleep Onset (WASO), Total Sleep Time (TST), and Sleep Efficiency (SE), and the later four outcomes were measured by Actiwatch and sleep diary, respectively.

Results

A total of seven articles with 434 participants were included. The meta-analysis revealed that acupuncture produced a significant improvement in the total PSQI score (MD 95 %CI = -2.16[-2.88, − 1.45], P < 0.001), but had no statistical significance on ISI scores compared with controls (MD 95 %CI = -1.53[-3.97, 0.91], P = 0.22). From the Actiwatch, there was no substantial disparity observed in the enhancement of Sleep Onset Latency (SOL) (MD 95 %CI = -6.40[-13.19, 0.39], P = 0.06), Wake After Sleep Onset (WASO) (MD 95 %CI = -1.45[-7.09, 4.20], P = 0.62), or Total Sleep Time (TST) (MD 95 %CI = 3.54 [-4.71, 11.79], P = 0.40) between the experimental group and the control group. However, a significant distinction was observed in Sleep Efficiency (SE) improvement (MD 95 %CI = 2.43 [0.14, 4.72], P = 0.04). From the sleep diary, there was a significant difference in the amelioration of SOL (MD 95 %CI = -9.15[-16.48, − 1.81], P = 0.01), TST (MD 95 %CI = 29.92 [16.74, 43.10], P < 0.001), and SE (MD 95 %CI = 4.57 [1.92, 7.23], P = 0.0007) between the experimental group and the control group. However, no significant divergence was observed in the improvement of WASO (MD 95 %CI = 4.53[-4.81, 13.87], P = 0.34). All reported acupuncture-related adverse events were mild in severity.

Conclusions

Acupuncture can partially alleviate insomnia symptoms in breast cancer patients. Moreover, acupuncture is safe and may serve as a dependable alternative therapy in clinical settings. Owing to the limited number of studies included, potential biases of heterogeneous interventions, and methodological weaknesses of long-term follow-up, more high-quality RCTs with large sample sizes should be conducted to evaluate acupuncture treatment.
背景:乳腺癌相关失眠是乳腺癌患者最常见的症状之一,针灸已越来越多地被用于治疗。然而,目前还没有专门探讨针灸治疗乳腺癌相关失眠症的有效性和安全性的荟萃分析:本综述旨在通过荟萃分析对现有文献进行系统分析,以评估针灸治疗乳腺癌相关失眠症的有效性和安全性:方法:在六个医学数据库中全面检索了截至 2024 年 4 月的既往随机对照试验(RCT)。主要结果为匹兹堡睡眠质量指数(PSQI)得分。次要结果包括失眠严重程度指数(ISI)、睡眠起始延迟(SOL)、睡眠起始后唤醒(WASO)、总睡眠时间(TST)和睡眠效率(SE),后四项结果分别通过Actiwatch和睡眠日记进行测量:结果:共纳入了 7 篇文章,434 名参与者。荟萃分析显示,针灸可显著改善 PSQI 总分(MD 95%CI=-2.16[-2.88, -1.45], PC结论:针灸可部分缓解失眠:针灸可部分缓解乳腺癌患者的失眠症状。此外,针灸是安全的,在临床上可作为一种可靠的替代疗法。由于纳入的研究数量有限、异质性干预的潜在偏倚以及长期随访的方法学缺陷,应开展更多高质量、大样本量的研究来评估针灸治疗。
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引用次数: 0
Dry needling techniques as a treatment for improving disability and pain in patients with different types of headache: A systematic review and meta-analysis 干针技术可改善不同类型头痛患者的残疾和疼痛:系统回顾与元分析》。
IF 3.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-09-15 DOI: 10.1016/j.ctim.2024.103085
Mahmoud Kandeel , Mohamed A. Morsy , Khalid M. Al Khodair , Sameer Alhojaily

Background

Headaches, a widespread neuromuscular ailment, pose a significant burden on individuals and society, necessitating both pharmacological and non-pharmacological interventions. Dry needling (DN) has surfaced as a notable non-pharmacological alternative for addressing headaches. We aim to compare DN intervention with the control group in the management of different types of headaches.

Methods

A comprehensive meta-analysis was conducted, encompassing a systematic exploration of five electronic databases up to May 2023, with studies assessed for validity using the Cochrane risk of bias tool. Eligible studies included those with a control group, which could consist of sham interventions, physiotherapy, or pharmacological treatments. Outcomes related to disability, headache intensity, and frequency were extracted and analyzed.

Results

Out of 4304 studies screened, 13 randomized controlled trials (RCTs) were included in this systematic review, of them 10 RCTs were included in the meta-analysis. A significant decline in the disability score and headache intensity was evident in the DN group compared to the control group, one and three-month follow-ups. Specifically, substantial reductions in headache frequency were prominent after one and three months post-intervention.

Conclusion

Dry needling manifests as a potent intervention, diminishing headache intensity and frequency, albeit with lower impact on disability scores. The observed benefits were especially pronounced after one and three months, though the heterogeneous nature of some data analyses mandates further detailed studies to gain a clearer understanding of DN's efficacy on the assessed outcomes.
背景:头痛是一种广泛存在的神经肌肉疾病,给个人和社会带来了沉重负担,需要药物和非药物干预。干针疗法(DN)已成为治疗头痛的一种显著的非药物疗法。我们旨在比较干针疗法与对照组对不同类型头痛的治疗效果:我们进行了一项全面的荟萃分析,对截至 2023 年 5 月的五个电子数据库进行了系统性探索,并使用 Cochrane 偏倚风险工具对研究的有效性进行了评估。符合条件的研究包括有对照组的研究,对照组可以是假干预、物理治疗或药物治疗。研究人员提取并分析了与残疾、头痛强度和频率相关的结果:在筛选出的 4304 项研究中,有 13 项随机对照试验(RCT)被纳入本系统综述,其中有 10 项 RCT 被纳入荟萃分析。与对照组相比,DN组的残疾评分和头痛强度在一个月和三个月的随访中明显下降。特别是在干预后的一个月和三个月,头痛频率明显降低:结论:干针疗法是一种有效的干预方法,可减轻头痛的强度和频率,但对残疾评分的影响较小。观察到的益处在一个月和三个月后尤为明显,但由于某些数据分析的不一致性,需要进一步开展详细研究,以便更清楚地了解干针疗法对评估结果的疗效。
{"title":"Dry needling techniques as a treatment for improving disability and pain in patients with different types of headache: A systematic review and meta-analysis","authors":"Mahmoud Kandeel ,&nbsp;Mohamed A. Morsy ,&nbsp;Khalid M. Al Khodair ,&nbsp;Sameer Alhojaily","doi":"10.1016/j.ctim.2024.103085","DOIUrl":"10.1016/j.ctim.2024.103085","url":null,"abstract":"<div><h3>Background</h3><div>Headaches, a widespread neuromuscular ailment, pose a significant burden on individuals and society, necessitating both pharmacological and non-pharmacological interventions. Dry needling (DN) has surfaced as a notable non-pharmacological alternative for addressing headaches. We aim to compare DN intervention with the control group in the management of different types of headaches.</div></div><div><h3>Methods</h3><div>A comprehensive meta-analysis was conducted, encompassing a systematic exploration of five electronic databases up to May 2023, with studies assessed for validity using the Cochrane risk of bias tool. Eligible studies included those with a control group, which could consist of sham interventions, physiotherapy, or pharmacological treatments. Outcomes related to disability, headache intensity, and frequency were extracted and analyzed.</div></div><div><h3>Results</h3><div>Out of 4304 studies screened, 13 randomized controlled trials (RCTs) were included in this systematic review, of them 10 RCTs were included in the meta-analysis. A significant decline in the disability score and headache intensity was evident in the DN group compared to the control group, one and three-month follow-ups. Specifically, substantial reductions in headache frequency were prominent after one and three months post-intervention.</div></div><div><h3>Conclusion</h3><div>Dry needling manifests as a potent intervention, diminishing headache intensity and frequency, albeit with lower impact on disability scores. The observed benefits were especially pronounced after one and three months, though the heterogeneous nature of some data analyses mandates further detailed studies to gain a clearer understanding of DN's efficacy on the assessed outcomes.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103085"},"PeriodicalIF":3.3,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Complementary therapies in medicine
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