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Profiling of Oral Squamous Cell Carcinoma of Lower Assam Region - A Hospital-Based Retrospective Study. 下阿萨姆邦地区口腔鳞状细胞癌的概况-一项基于医院的回顾性研究
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_90_24
Debojyoti Roy, Thamizholi Selvaraju, Bharadwaj Bordoloi, BahniSikha Pathak, Divjot Ahluwalia

Background: Oral cancer is one of the ten most common cancers worldwide and the sixth most common type of all cancer in India. Among the oral malignancies, oral squamous cell carcinoma (OSCC) is the most common, accounting for more than 90% of oral cancer and hence a significant public health concern.

Aim: The aim of this study was to evaluate clinicopathological and demographic profiling of OSCC in a district and adjacent area of lower Assam.

Settings and design: This was a retrospective observational study.

Materials and methods: A total of 140 histologically confirmed OSCC patients diagnosed at the Regional Cancer Centre in the district between the period 2022 April and 2023 October constitute our study sample size in this study. The duration of the study was 1½ years.

Statistical analysis: The clinical and histopathological features were analyzed using descriptive statistics. Statistical Package for the Social Science (SPSS) version 23.0 was used.

Results: OSCC constitutes 23.97% of head-and-neck cancer. The incidence of OSCC was higher in males. The highest number of patients was in the age group of 50-59. The most common site of OSCC was the buccal mucosa followed by the tongue. Most of the cases were well differentiated, the number being 82 (58.57%). Most of the patients were in Stage III and Stage IV.

Conclusions: The present study highlights that in the lower Assam region, the majority of the OSCC patients are middle-aged male patients with advanced stages of OSCC. The findings from the present study can be used to compare the scenario of OSCC in other parts of Assam and North East India and also can be used for a follow-up study.

背景:口腔癌是世界上十大最常见的癌症之一,在印度所有癌症中排名第六。在口腔恶性肿瘤中,口腔鳞状细胞癌(OSCC)最为常见,占口腔癌的90%以上,因此是一个重大的公共卫生问题。目的:本研究的目的是评估下阿萨姆邦一个地区和邻近地区OSCC的临床病理和人口统计学特征。背景和设计:这是一项回顾性观察性研究。材料和方法:在2022年4月至2023年10月期间,在该地区的区域癌症中心诊断的140例组织学证实的OSCC患者构成了本研究的研究样本量。研究的持续时间为1年半。统计学分析:采用描述性统计分析临床和组织病理学特征。使用SPSS 23.0版本的社会科学统计软件包。结果:OSCC占头颈癌的23.97%。男性的OSCC发病率较高。患者以50-59岁年龄组最多。口腔鳞状细胞癌最常见的部位是颊粘膜,其次是舌头。多数病例分化良好,为82例(58.57%)。结论:本研究强调,在下阿萨姆地区,大多数OSCC患者为中晚期的中年男性OSCC患者。本研究的结果可用于比较阿萨姆邦和印度东北部其他地区的OSCC情况,也可用于后续研究。
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引用次数: 0
The Minamata Convention - The Road to Safer Practices. 《水俣公约-通往更安全做法之路》。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_570_24
Girish Malleshappa Sogi
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引用次数: 0
Exploring the Role of Health-care Professionals and Impact of Precision Medicine on Health Outcomes and Efficiency. 探索医疗保健专业人员的作用和精准医学对健康结果和效率的影响。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_323_24
Saurabh RamBihariLal Shrivastava, Anup Mukund Marar, Prateek Sudhakar Bobhate, Ankit Badge

The inclusion of precision medicine in medical education represents a paradigm shift, as it is expected to transform the way in which health care will be delivered to patients in future. This shift is predominantly reported as precision medicine strongly advocates for the delivery of personalized care to patients after giving due consideration to the genetic makeup, biomarker level, etc., of the individual patient. Medical professionals are expected to discharge a wide range of roles since the introduction of precision medicine in the health-care industry. Training of medical students and health professionals in the domain of precision medicine is expected to significantly influence patient outcomes and enhance the efficiency of the health-care sector. In conclusion, precision medicine is expected to have a huge impact on medical professionals and the health sector, it is the need of the hour to strengthen its implementation process across medical colleges and health-care facilities.

将精准医学纳入医学教育代表着一种范式转变,因为它有望改变未来向患者提供医疗保健的方式。这一转变主要是由于精准医学强烈主张在考虑到个体患者的基因组成、生物标志物水平等因素后,为患者提供个性化护理。自从在医疗保健行业引入精准医疗以来,医疗专业人员有望发挥广泛的作用。在精准医疗领域对医科学生和卫生专业人员进行培训,预计将对患者的治疗结果产生重大影响,并提高卫生保健部门的效率。总之,精准医疗预计将对医疗专业人员和卫生部门产生巨大影响,当务之急是加强其在医学院和卫生保健机构的实施过程。
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引用次数: 0
Roadmap for the Development and Implementation of Entrustable Professional Activities to Enable Effective Clinical Training. 开发和实施可信赖的专业活动以实现有效临床培训的路线图。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_148_24
Saurabh RamBihariLal Shrivastava, Shubhada Gade, Sunita Vagha

In the field of clinical training, entrustable professional activities (EPAs) generally deal with those activities that health-care professionals will be encountering in their routine practice, and thus exposure to these activities prepares them for their future clinical practice. Workplace-based assessment tools have been used to assess the progress of medical students across these defined EPAs. The act of development of EPAs essentially requires the adoption of a systematic process to identify and define the core tasks and responsibilities that medical students must be able to perform independently in a specific specialty. The process of integration of EPAs into the medical school curriculum essentially requires systematic planning and implementation to ensure that students get an adequate number of opportunities to develop and demonstrate the desired competencies. In conclusion, EPAs provide an excellent framework for transforming medical education by preparing medical students to be ready for the complexities of health-care delivery.

在临床培训领域,可信赖的专业活动(EPAs)通常涉及保健专业人员在日常实践中遇到的那些活动,因此,接触这些活动可以为他们将来的临床实践做好准备。基于工作场所的评估工具已被用于评估医学生在这些已定义的环境评估中的进展。发展专业技能的行为本质上要求采用一个系统的过程来确定和定义医学生在特定专业中必须能够独立执行的核心任务和责任。将EPAs纳入医学院课程的过程基本上需要系统的规划和实施,以确保学生有足够的机会发展和展示所需的能力。总而言之,环境保护方案提供了一个极好的框架,通过使医学生为提供保健服务的复杂性做好准备,从而转变医学教育。
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引用次数: 0
Extrafollicular Adenomatoid Odontogenic Tumors: A Series of Five Rare Cases with an Insight into Its Clinicopathological Aspects. 滤泡外腺瘤样牙源性肿瘤:5例罕见病例的临床病理分析。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_230_24
Debarati Ray, Snehanjan Sarangi, Tathagata Bhattacharjee, Jay Gopal Ray

Adenomatoid odontogenic tumors (AOT), first described by Steensland in 1905, are benign, slowly enlarging, nonaggressive, odontogenic epithelial neoplasms comprising 3%-7% of all odontogenic tumors. They tend to originate from the dental lamina remnants or the reduced enamel epithelium. Mutation at codon 12 of KRAS oncogene (Kirsten rat sarcoma viral oncogene homolog) plays a pivotal role in the pathogenesis. AOTs demonstrate three clinicopathological spectrums, namely follicular, extrafollicular, and peripheral. The extrafollicular AOTs are hypothesized to originate from a stimulus triggering the dental lamina remnants. While intraosseous follicular AOTs are fairly common (70.8%), the extrafollicular counterparts are infrequent (24%), and novel entities that may mimic other lesions due to the absence of tooth inside. Herein, we elucidate a series of five unique extrafollicular AOT cases with a relevant emphasis on its pathogenesis and clinico-radiological aspects. This report aims to add another significant record to the literature pertaining to the compilation of extrafollicular AOTs.

腺瘤样牙源性肿瘤(AOT)由Steensland于1905年首次描述,是一种良性的、缓慢增大的、非侵袭性的牙源性上皮肿瘤,占所有牙源性肿瘤的3%-7%。它们往往起源于牙板残余物或减少的牙釉质上皮。KRAS癌基因(Kirsten大鼠肉瘤病毒癌基因同源物)密码子12突变在其发病中起关键作用。aot表现出三种临床病理特征,即滤泡性、滤泡外性和外周性。滤泡外aot被认为是由刺激触发牙板残余引起的。虽然骨内滤泡aot相当常见(70.8%),但滤泡外aot并不常见(24%),由于内部没有牙齿,可能会出现类似其他病变的新实体。在此,我们阐述了一系列的五个独特的滤泡外AOT病例,并强调了其发病机制和临床放射学方面。本报告的目的是增加另一个重要的记录,以文献有关的汇编滤泡外aot。
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引用次数: 0
Orthodontic Treatment of Anterior Open Bite Caused by a Car Accident. 车祸致前牙开咬的正畸治疗。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_537_23
Naoto Hirose, Makoto Yanoshita, Sayuri Nishiyama, Naoki Kubo, Daiki Kita, Eri Tsuboi, Kotaro Tanimoto

This article outlines the orthodontic treatment of a 21-year-old female patient with an open bite and temporomandibular joint disorders (TMDs) that developed after a severe car accident. The treatment plan utilized temporary anchorage devices (TADs) for upper molar intrusion to correct the open bite without resorting to orthognathic surgery. Over a period of 3 years, the treatment achieved a stable occlusion, normalized molar relationships, and improved esthetics. Despite the persistent of TMD symptoms, the patient experienced enhanced jaw movement and a reduction in abnormal chewing cycles. The combination of orthodontic treatment with TADs and splint therapy contributed to successfully restoring both esthetic and functional aspects. This case underscores the efficacy of TADs in addressing trauma-induced malocclusions, highlighting the potential for minimal intervention to achieve comprehensive treatment outcomes.

本文概述了一名21岁女性患者在严重车祸后发生的开放性咬伤和颞下颌关节紊乱(TMDs)的正畸治疗。治疗方案采用临时支抗装置(TADs)矫正上磨牙内嵌,不需要进行正颌手术。在3年的时间里,治疗取得了稳定的咬合,正常化的磨牙关系,并改善了美观。尽管TMD症状持续存在,但患者的下颌运动增强,异常咀嚼周期减少。正畸治疗与TADs和夹板治疗的结合有助于成功地恢复审美和功能方面。本病例强调了TADs在解决创伤性错颌的疗效,强调了最小干预实现综合治疗结果的潜力。
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引用次数: 0
A Critical Review of YouTube Videos on the Socket-shield Technique: A Content-quality Analysis. 对socket屏蔽技术的YouTube视频的评论:内容质量分析。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_317_24
Urvi Echhpal, Subhabrata Maiti, Rajendra Prabhu Abhinav

Dental students often prefer social media for its accessibility and low cost but must critically evaluate the content before applying it in practice. This study analyzed YouTube content on socket shielding. A new Google account was created to search for "Socket Shield Technique" and "Partial Extraction Therapy." Eligible videos were assessed for quality using the Global Quality (GQ) tool and the DISCERN tool. Statistical analysis was performed using the Statistical Package for the Social Sciences software. Results showed an average of 28.35 likes per video, no dislikes, and substandard content indicated by a DISCERN score of 25.25 ± 2.4 and a GQ score of 1.82 ± 0.38. The study concludes that video content on socket shielding is not reliable, emphasizing the importance of clinical observation and hands-on practice.

牙科专业的学生通常更喜欢社交媒体,因为它的可访问性和低成本,但在应用于实践之前必须对内容进行批判性评估。本研究分析了YouTube上关于插座屏蔽的内容。创建了一个新的谷歌帐户,用于搜索“Socket Shield technology”和“Partial Extraction Therapy”。使用全球质量(GQ)工具和DISCERN工具评估合格视频的质量。使用社会科学软件的统计软件包进行统计分析。结果显示,每个视频平均有28.35个赞,没有不喜欢,不合格内容,辨别评分为25.25±2.4,GQ评分为1.82±0.38。本研究认为,关于插座屏蔽的视频内容不可靠,强调临床观察和动手实践的重要性。
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引用次数: 0
Evaluation of the Changes in the Alveolar Bone and Root Length after Maxillary Anterior Tooth Retraction and the Factors Influencing Them. 上颌前牙后牙槽骨和牙根长度变化及其影响因素的评价。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-12-24 DOI: 10.4103/ccd.ccd_325_24
S Harinarayanan, Sanju Somaiah, B Goutham, Sunil Muddaiah

Introduction: There is a scarcity of studies in which both alveolar bone remodeling and root resorption are simultaneously assessed and compared against possible influencing factors such as rate of retraction and change in inclination. The aim of our study was to assess the changes in the alveolar bone thickness and root length of the maxillary anterior teeth after retraction and correlate it to the potential influencing factors, namely rate of retraction and change in inclination.

Subjects and methods: Ten patients requiring upper premolar extraction as part of their treatment were included in the study. Alveolar bone and root length changes were measured using cone beam computed tomography and the rate of retraction and change in inclination were assessed using lateral cephalograms. Two readings: Preretraction and postretraction were taken. Statistical analysis was done using Paired rank t-test and Spearman's rank correlation tests. Significance level was set at P < 0.05.

Results and conclusions: The labial alveolar bone thickness showed an increase, whereas the palatal and total alveolar bone thickness showed a decrease. Root resorption was observed in all teeth. Alveolar bone changes showed a positive correlation to the rate of retraction and a negative correlation to the change in inclination. The root length change showed a positive correlation to the change in inclination.

对牙槽骨重塑和牙根吸收同时进行评估和比较可能的影响因素(如牙槽骨内缩回率和牙槽骨倾斜度变化)的研究很少。我们的研究目的是评估上颌前牙内缩后牙槽骨厚度和根长度的变化,并将其与潜在的影响因素,即内缩率和倾斜度的变化联系起来。研究对象和方法:选取10例需要拔除上前磨牙的患者作为治疗的一部分。使用锥形束计算机断层扫描测量牙槽骨和牙根长度的变化,使用侧位脑电图评估牙槽骨的内缩率和倾斜变化。两个读数:牵拉前和牵拉后。统计学分析采用配对秩t检验和Spearman秩相关检验。P < 0.05为显著性水平。结果与结论:唇牙槽骨厚度增加,腭牙槽骨和全牙槽骨厚度减少。所有牙根均有吸收。牙槽骨变化与牙槽内收放率呈正相关,与牙槽内倾角变化呈负相关。根长变化与倾角变化呈显著正相关。
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引用次数: 0
Benign Fibrous Histiocytoma of Gingiva: A Rare Case Report. 牙龈良性纤维组织细胞瘤:罕见病例报告
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-09-25 DOI: 10.4103/ccd.ccd_535_23
Bhavani Nagendra Sangala, Ashwin Jawdekar, Sheetal S Choudhari, Urvashi R Tank, Kirti Balkrishna Buva, Sneha Masne Deshpande

Fibrous histiocytoma is a benign soft-tissue neoplasm that commonly involves the dermis. It is rare in the oral cavity. This lesion creates a diagnostic dilemma due to its nonspecific clinical appearance and microscopic similarities with other benign fibrous tissue lesions. Microscopically, it shows the proliferation of both spindle-shaped fibroblasts and histiocytes. Surgical excision is the treatment of choice with a good prognosis. The purpose of this paper is to report a rare case of gingival benign fibrous histiocytoma occurring in an 11-year-old female patient. The diagnosis of this lesion is based on combined clinical, histopathological, and immunohistochemical features.

纤维组织细胞瘤是一种良性软组织肿瘤,通常累及真皮层。口腔中很少见。由于这种病变的临床表现无特异性,且在显微镜下与其他良性纤维组织病变相似,因此造成了诊断上的难题。显微镜下可看到纺锤形成纤维细胞和组织细胞增生。手术切除是预后良好的首选治疗方法。本文旨在报告一例罕见的牙龈良性纤维组织细胞瘤病例,该病例发生在一名 11 岁的女性患者身上。该病变的诊断基于临床、组织病理学和免疫组化的综合特征。
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引用次数: 0
Comparative Evaluation of Hard- and Soft-tissue Changes in Immediate Implant Placement Using Flapless Approach with and without Demineralized Freeze-dried Bone Allograft Clinically and Radiographically Using Cone-beam Computed Tomography. 利用锥形束计算机断层扫描技术,对采用无瓣法即刻植入种植体时使用和不使用去矿化冻干骨异植体的硬组织和软组织变化进行临床和影像学比较评估。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-09-25 DOI: 10.4103/ccd.ccd_246_23
Mukesh Purohit, Abhay P Kolte, Rajashri A Kolte, Divya S Trivedi

Objectives: The present study evaluated hard- and soft-tissue changes in immediate implants using flapless approach with and without demineralized freeze-dried bone allograft (DFDBA) clinically and radiographically using cone-beam computed tomography (CBCT).

Materials and methods: Thirty-two sites in patients requiring immediate implants in the maxillary anterior region including the premolars were grouped according to the treatment provided with (test group) or without (control group) DFDBA. Plaque index, probing depth, soft-tissue assessment using Testori Esthetic Score (TS), and ridge width were recorded at baseline and postoperatively at 6 and 12 months, while crestal bone height (CBH), buccal bone thickness (BBT), jump space (JS), and gingival thickness were evaluated using CBCT at baseline and 12 months.

Results: Considerable differences among the different time lines and the groups in favor of the test group were prominently seen on the midfacial aspects at 12 months, with CBH values of -0.28 ± 0.17 mm in the test group as compared to -0.78 ± 0.34 in the control group (P < 0.0001). The JS was maximum on the buccal aspects being 1.42 ± 0.87 mm in the test group and 1.12 ± 0.81 mm in the control group which reduced at 12 months to 0.13 ± 0.35 mm and 0.73 ± 0.79 mm, respectively.

Conclusion: Immediate implants with DFDBA augmentation using a flapless protocol demonstrated reduced CBH with resolution of JS and increased BBT, especially at the coronal aspects which influence the tissue stability and overall esthetics.

研究目的本研究使用锥形束计算机断层扫描(CBCT),通过临床和影像学方法,评估了采用无瓣法、使用或不使用去矿化冻干骨异体移植(DFDBA)即刻种植体的硬组织和软组织变化:根据使用(试验组)或未使用(对照组)DFDBA进行治疗的情况,对上颌前牙区包括前磨牙在内的32个需要即刻种植的部位进行分组。在基线和术后 6 个月和 12 个月时记录牙菌斑指数、探诊深度、使用 Testori 美学评分(TS)进行的软组织评估以及牙脊宽度,在基线和 12 个月时使用 CBCT 评估牙槽骨高度(CBH)、颊骨厚度(BBT)、跳空隙(JS)和牙龈厚度:在 12 个月时,不同时间线和不同组别之间存在显著差异,测试组在颌面中部表现突出,CBH 值为 -0.28 ± 0.17 mm,而对照组为 -0.78 ± 0.34 mm(P < 0.0001)。颊侧的 JS 最大,试验组为 1.42 ± 0.87 mm,对照组为 1.12 ± 0.81 mm,12 个月后分别降至 0.13 ± 0.35 mm 和 0.73 ± 0.79 mm:采用无翻瓣方案进行 DFDBA 增量的即刻种植体显示出 CBH 的降低、JS 的消退和 BBT 的增加,尤其是在影响组织稳定性和整体美观的冠状面。
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引用次数: 0
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Contemporary Clinical Dentistry
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