Pub Date : 2017-11-10DOI: 10.15406/JNSK.2017.07.00261
S. Ray
Submit Manuscript | http://medcraveonline.com findings affecting the visual, behavioral and oculomotor abnormalities without prominent motor dysfunction [1]. Segarra coined the term ‘mesencephalic artery syndrome’ and used the term ‘somnolent mutism’ to describe it [2]. Overall, occlusion of the basilar artery comprises 1% to 4% of all ischemic strokes [3]. But symptoms of top of basilar are a distinct subdivision of the former and need to be properly categorized.
{"title":"Basilar Artery Ischemic Syndromes- A Brief Discussion of Current Concepts","authors":"S. Ray","doi":"10.15406/JNSK.2017.07.00261","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00261","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com findings affecting the visual, behavioral and oculomotor abnormalities without prominent motor dysfunction [1]. Segarra coined the term ‘mesencephalic artery syndrome’ and used the term ‘somnolent mutism’ to describe it [2]. Overall, occlusion of the basilar artery comprises 1% to 4% of all ischemic strokes [3]. But symptoms of top of basilar are a distinct subdivision of the former and need to be properly categorized.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131934025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-07DOI: 10.15406/jnsk.2017.07.00260
M. Elsebaey, M. Elgohary
56 year old male from Rosetta complained of acute onset of neck pain for about 2 months with progressive course of upper limbs weakness with no sphincter affection. No previous dental nor neck nor back surgery nor acupuncture. History of renal impairment and on medical treatment for about 4 years. Body temperature was about 38.2 C. Physical examination showed marked mid neck tenderness, no palpable masses were felt, no lymph nodes were felt. Neurological examination revealed grade 3 paraparesis in the upper limbs while grade zero in both lower limbs on Medical Research Council (MRC) scale. Preservation of the deep sensation while loss of the superficial sensation, positive Hoffman sign and positive planter reflex. Magnetic Resonance imaging of the cervical spine showing ventral cervical spinal cord compression by an epidural abscess extending from the apex of dens to the level of C5. Decreased spinal canal diameter and mild spinal cord compression were present (Figure 1).
{"title":"Extensive Cervical Epidural Abscess: Case Report","authors":"M. Elsebaey, M. Elgohary","doi":"10.15406/jnsk.2017.07.00260","DOIUrl":"https://doi.org/10.15406/jnsk.2017.07.00260","url":null,"abstract":"56 year old male from Rosetta complained of acute onset of neck pain for about 2 months with progressive course of upper limbs weakness with no sphincter affection. No previous dental nor neck nor back surgery nor acupuncture. History of renal impairment and on medical treatment for about 4 years. Body temperature was about 38.2 C. Physical examination showed marked mid neck tenderness, no palpable masses were felt, no lymph nodes were felt. Neurological examination revealed grade 3 paraparesis in the upper limbs while grade zero in both lower limbs on Medical Research Council (MRC) scale. Preservation of the deep sensation while loss of the superficial sensation, positive Hoffman sign and positive planter reflex. Magnetic Resonance imaging of the cervical spine showing ventral cervical spinal cord compression by an epidural abscess extending from the apex of dens to the level of C5. Decreased spinal canal diameter and mild spinal cord compression were present (Figure 1).","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114990668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-30DOI: 10.15406/JNSK.2017.07.00259
Amina Daude, S. Chowdhury
Motor neuron disease (MND) is a group of neurodegenerative disorders related to selective degeneration of motor neurons in the brain and spinal cord. Studies of the incidence, prevalence and demographic characteristics of patients with MND have mostly been done in the industrialized countries. We know petite about the disease in Africa in general and southern Africa in particular. Our anecdotal evidence from the neurology and geriatric medicine clinics suggests that the disease is not uncommonly seen in younger patients.
{"title":"Review of 48 Cases of Motor Neuron Disease seen at Groote Schuur Hospital: A Pilot Study","authors":"Amina Daude, S. Chowdhury","doi":"10.15406/JNSK.2017.07.00259","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00259","url":null,"abstract":"Motor neuron disease (MND) is a group of neurodegenerative disorders related to selective degeneration of motor neurons in the brain and spinal cord. Studies of the incidence, prevalence and demographic characteristics of patients with MND have mostly been done in the industrialized countries. We know petite about the disease in Africa in general and southern Africa in particular. Our anecdotal evidence from the neurology and geriatric medicine clinics suggests that the disease is not uncommonly seen in younger patients.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128568299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-28DOI: 10.15406/JNSK.2017.07.00258
Stavros J. Baloyannis
Franz Gerstenbrand graduated from Vienna University, “Cum Laude”, in 1950, and immediately, he started postgraduate training in Neurology and Psychiatry at the same University, under the directorship of Prof. Hans Hoff. In 1976, he was elected Professor of Neurology and appointed head of the University Department of Neurology at Innsbruck University, where he stayed til his retirement in 1994. Under his directorship the department of Neurology became one of the best organized and functioned university departments in Europe.
{"title":"Franz Gerstenbrand (1924-2017) The world ambassador of Neurosciences In Memoriam Aeternam","authors":"Stavros J. Baloyannis","doi":"10.15406/JNSK.2017.07.00258","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00258","url":null,"abstract":"Franz Gerstenbrand graduated from Vienna University, “Cum Laude”, in 1950, and immediately, he started postgraduate training in Neurology and Psychiatry at the same University, under the directorship of Prof. Hans Hoff. In 1976, he was elected Professor of Neurology and appointed head of the University Department of Neurology at Innsbruck University, where he stayed til his retirement in 1994. Under his directorship the department of Neurology became one of the best organized and functioned university departments in Europe.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131629085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-25DOI: 10.15406/JNSK.2017.07.00257
Ikram Asad, Berti Aldo, Calder Christopher, A. QuadriSyed, Zafar Atif
Submit Manuscript | http://medcraveonline.com stroke due to vasculitis of cerebral blood vessels [2]. At least three cases of stroke in the setting of WNE have been reported: a young girl with MCA stroke, elderly women with cerebellar stroke, and an elderly man with a nonspecific periventricular stroke [2-4]. We report the first case of West Nile Meningitis/Encephalitis complicated by Pontine Stroke.
{"title":"A Case of West Nile Meningitis Complicated by Pontine Stroke","authors":"Ikram Asad, Berti Aldo, Calder Christopher, A. QuadriSyed, Zafar Atif","doi":"10.15406/JNSK.2017.07.00257","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00257","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com stroke due to vasculitis of cerebral blood vessels [2]. At least three cases of stroke in the setting of WNE have been reported: a young girl with MCA stroke, elderly women with cerebellar stroke, and an elderly man with a nonspecific periventricular stroke [2-4]. We report the first case of West Nile Meningitis/Encephalitis complicated by Pontine Stroke.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126584254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-23DOI: 10.15406/jnsk.2017.07.00256
Bah Ab, S. I. Sory, B. Daniel, K. Béavogui
Submit Manuscript | http://medcraveonline.com been described in the literature [2]. A nail is rarely used as a weapon and can forcefully penetrate the skull bone and cause intracerebral lesions due to the rigid structure and narrow tip of the object. Penetrating intracranial injuries by a nail with infectious complications followed by positive recovery as the present case have not yet been reported in the literature.
{"title":"Penetrating Intracranial Injury by a Nail: Case Report","authors":"Bah Ab, S. I. Sory, B. Daniel, K. Béavogui","doi":"10.15406/jnsk.2017.07.00256","DOIUrl":"https://doi.org/10.15406/jnsk.2017.07.00256","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com been described in the literature [2]. A nail is rarely used as a weapon and can forcefully penetrate the skull bone and cause intracerebral lesions due to the rigid structure and narrow tip of the object. Penetrating intracranial injuries by a nail with infectious complications followed by positive recovery as the present case have not yet been reported in the literature.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129525535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-23DOI: 10.15406/jnsk.2017.07.00255
Xin Wang, A. Hubbard, G. Tan
Myelitis, Neuromylitis Optica (NMO) and Multiple Sclerosis (MS) are clinic common infectious diseases in spinal cord that are costly, progressive and often cause life-time disabilities. Methylprednisolone Sodium Succinate, a corticosteroid hormone, is a routine effective therapeutic drug for center nerve system (CNS) inflammation, especially applied for MS attacks [1]. However, long term and/or high dose use of corticosteroid hormone has serious side effects such as osteonecrosis of femoral head, cerebral hemorrhage, unstable blood pressure and blood sugar, disorder of kidney [2]. Therefore, corticosteroid hormone therapy is limited on clinical application.
{"title":"Alpha Lipoic Acid (Ala) Combining with Corticosteroid Hormone Improves the Outcome of Infectious Diseases in Spinal Cord (10 Cases Study)","authors":"Xin Wang, A. Hubbard, G. Tan","doi":"10.15406/jnsk.2017.07.00255","DOIUrl":"https://doi.org/10.15406/jnsk.2017.07.00255","url":null,"abstract":"Myelitis, Neuromylitis Optica (NMO) and Multiple Sclerosis (MS) are clinic common infectious diseases in spinal cord that are costly, progressive and often cause life-time disabilities. Methylprednisolone Sodium Succinate, a corticosteroid hormone, is a routine effective therapeutic drug for center nerve system (CNS) inflammation, especially applied for MS attacks [1]. However, long term and/or high dose use of corticosteroid hormone has serious side effects such as osteonecrosis of femoral head, cerebral hemorrhage, unstable blood pressure and blood sugar, disorder of kidney [2]. Therefore, corticosteroid hormone therapy is limited on clinical application.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124204815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-12DOI: 10.15406/JNSK.2017.07.00254
Tamajit Chakraborty, D. Sharma, A. Goyal, V. Madan
Ossification of the ligamentum flavum (OLF) was discovered by Polgar and further described by Yamaguchi and Isuruni [1]. Among the thoracic myelopathies, its incidence is less than that of ossification of the posterior longitudinal ligament (OPLL) and higher than that of herniated nucleus pulposus (HNP) [1]. It is mostly prevalent in Japan and other East Asian countries such as Korea and China [2]. Achondroplasia is a genetic disorder of bone growth with congenital spinal stenosis being a well known complication [3]. Degenerative changes of the spine, such as disc herniation, degenerative spondylosis and arthrosis result in worsening of stenosis [4]. However, symptomatic spinal stenosis due by ossification of the ligamentum flavum (OLF) in achondroplasia is extremely rare [5,6]. We present a rare case of spinal stenosis due to ossified ligamentum flavum in a 30 year old Indian female of achondroplasia presenting as dorsal myelopathy.
{"title":"A Rare Case of Ossification of Ligamentum Flavum presenting as Dorsal Myelopathy in Achondroplasia","authors":"Tamajit Chakraborty, D. Sharma, A. Goyal, V. Madan","doi":"10.15406/JNSK.2017.07.00254","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00254","url":null,"abstract":"Ossification of the ligamentum flavum (OLF) was discovered by Polgar and further described by Yamaguchi and Isuruni [1]. Among the thoracic myelopathies, its incidence is less than that of ossification of the posterior longitudinal ligament (OPLL) and higher than that of herniated nucleus pulposus (HNP) [1]. It is mostly prevalent in Japan and other East Asian countries such as Korea and China [2]. Achondroplasia is a genetic disorder of bone growth with congenital spinal stenosis being a well known complication [3]. Degenerative changes of the spine, such as disc herniation, degenerative spondylosis and arthrosis result in worsening of stenosis [4]. However, symptomatic spinal stenosis due by ossification of the ligamentum flavum (OLF) in achondroplasia is extremely rare [5,6]. We present a rare case of spinal stenosis due to ossified ligamentum flavum in a 30 year old Indian female of achondroplasia presenting as dorsal myelopathy.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128195044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-11DOI: 10.15406/JNSK.2017.07.00252
S. N. Bernardino, Fern, O. H. M. Souza, R. Silva-Néto, H. A. Martins, Luiz Ataíde Júnior, R. Martins, Isabel Nery Bernardino de Souza, Regina Nery Bernardino de Souza
There is a technique to measure the physiology of the nociceptive system, known as pressure algometry. It has a direct action on the responsive peripheral nociceptors to the pressure stimuli, making possible the study of the nociceptive integrity in normal individuals or with different pain syndromes [6]. Our aim was to determine the pain threshold in migraine and tensiontype headache patients by pressure algometry in craniocervical muscles as in nerves peripheral in both genders. Patients and Methods
{"title":"Pain Threshold in Migraine and Tension-Type Headache by Pressure Algometry in Craniocervical Muscles and Peripheral Nerves in Both Genders","authors":"S. N. Bernardino, Fern, O. H. M. Souza, R. Silva-Néto, H. A. Martins, Luiz Ataíde Júnior, R. Martins, Isabel Nery Bernardino de Souza, Regina Nery Bernardino de Souza","doi":"10.15406/JNSK.2017.07.00252","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00252","url":null,"abstract":"There is a technique to measure the physiology of the nociceptive system, known as pressure algometry. It has a direct action on the responsive peripheral nociceptors to the pressure stimuli, making possible the study of the nociceptive integrity in normal individuals or with different pain syndromes [6]. Our aim was to determine the pain threshold in migraine and tensiontype headache patients by pressure algometry in craniocervical muscles as in nerves peripheral in both genders. Patients and Methods","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122592701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-11DOI: 10.15406/JNSK.2017.07.00253
Tseng Ky
Air pollutant gases include ground-level ozone, carbon monoxide, sulfur dioxides and nitrogen oxides, particulate matter, organic compounds, including polycyclic aromatic hydrocarbons and endotoxins, and metals [1]. Nitrogen is released during fuel combustion and combines with oxygen atoms in the atmosphere to produce nitric oxide and other nitrogen oxides, which can be inhaled by the upper respiratoy tract. Nitrogen oxides are a source of neurotoxin; thus, minimizing exposure and detecting its levels in the brain is pertinent. Nitrogen oxides have been shown to be associated with dementia, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). NO2 inhalation by C57BL/6J mice with amyloid precursor protein and presenilin 1 mutations aggravated β-amyloid accumulation, caused deterioration of spatial learning and memory and induced pathological abnormalities and cognitive defects related to AD compared to naïve control mice [2]. Furthermore, nitrogen oxides were associated with increased dementia risk in two clinical cohort studies [3]. One was a 15-year study of 1806 healthy men and women in Sweden [4], and another was a 10-year study of nearly 30,000 individuals in Taiwan [5].
{"title":"Nitrogen Oxides Induced Neurodegeneration as Examined by Nuclear Magnetic Resonance","authors":"Tseng Ky","doi":"10.15406/JNSK.2017.07.00253","DOIUrl":"https://doi.org/10.15406/JNSK.2017.07.00253","url":null,"abstract":"Air pollutant gases include ground-level ozone, carbon monoxide, sulfur dioxides and nitrogen oxides, particulate matter, organic compounds, including polycyclic aromatic hydrocarbons and endotoxins, and metals [1]. Nitrogen is released during fuel combustion and combines with oxygen atoms in the atmosphere to produce nitric oxide and other nitrogen oxides, which can be inhaled by the upper respiratoy tract. Nitrogen oxides are a source of neurotoxin; thus, minimizing exposure and detecting its levels in the brain is pertinent. Nitrogen oxides have been shown to be associated with dementia, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). NO2 inhalation by C57BL/6J mice with amyloid precursor protein and presenilin 1 mutations aggravated β-amyloid accumulation, caused deterioration of spatial learning and memory and induced pathological abnormalities and cognitive defects related to AD compared to naïve control mice [2]. Furthermore, nitrogen oxides were associated with increased dementia risk in two clinical cohort studies [3]. One was a 15-year study of 1806 healthy men and women in Sweden [4], and another was a 10-year study of nearly 30,000 individuals in Taiwan [5].","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121029135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：