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Herbal medicine for cancer patients: An evidence based review 癌症患者的草药:基于证据的回顾
Pub Date : 2007-12-31 DOI: 10.5580/502
Janelle Wheat, G. Currie
Complementary and alternative medicine (CAM) is widely embraced by cancer patients due to largely patient driven demands for integration of herbal therapies into cancer treatment. The value of herbal medicine in cancer patients can only be fully realised when prescription is integrated into conventional cancer management models; a medico rather than patient driven strategy. Integrated medicine is a holistic approach to cancer care, with some herbal medicines showing proven effectiveness as adjuvants to conventional medical treatments. At the present time there is little evidence of a systematic process of evaluation or dialogue between mainstream medicine and herbal medicine practitioners. This review offers an evidence-based perspective of herbal medicine for cancer prevention, cancer treatment, managing cancer survival and palliation.
补充和替代医学(CAM)被癌症患者广泛接受,主要是由于患者对将草药疗法整合到癌症治疗中的需求。只有将处方纳入传统的癌症管理模式,草药对癌症患者的价值才能充分实现;这是一种以医生而不是病人为导向的策略。综合医学是癌症治疗的一种整体方法,一些草药作为传统医学治疗的辅助药物已被证明有效。目前,几乎没有证据表明主流医学和草药医生之间有系统的评估过程或对话。本文综述了以证据为基础的草药在癌症预防、癌症治疗、癌症生存管理和姑息治疗中的应用。
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引用次数: 42
Unani Medicine: Introduction and Present Status in India 乌纳尼医学:在印度的介绍和现状
Pub Date : 2007-12-31 DOI: 10.5580/2d0
Shoaib Ahmad
INTRODUCTION The Unani system of medicine; sometimes referred to as Greeco-Arab medicine or Unani Tibb; is based on Greek philosophy. As per this traditional system, the human body is composed of four basic elements: earth, air, water and fire having cold, hot, wet and dry temperaments respectively. The body fluids are composed of four humors: blood, phlegm, yellow bile and black bile. These humors have their own temperament:
乌纳尼医学体系;有时被称为希腊-阿拉伯医学或Unani Tibb;都是以希腊哲学为基础的。根据这一传统系统,人体由四种基本元素组成:土、气、水和火,分别具有冷、热、湿和干的气质。体液由四种体液组成:血、痰、黄胆汁和黑胆汁。这些幽默都有自己的气质:
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引用次数: 21
Effects Of Annona Muricata (Linn) On The Morphology Of Pancreatic Islet Cells Of Experimentally-Induced Diabetic Wistar Rats 野牡丹对实验性糖尿病大鼠胰岛细胞形态的影响
Pub Date : 2007-12-31 DOI: 10.5580/229c
D. Adeyemi, O. Komolafe, S. O. Adewole, E. Obuotor, T. Adenowo
The study was designed to evaluate the effects of methanolic extract of Annona muricata leaves on the pancreatic islet cells of streptozotocin induceddiabetic rats. Thirty adult Wistar rats were randomly assigned into three groups (A, B and C) of ten rats each. Group A was the control, Group B was untreated diabetic group and group C was A. muricata-treated group. Diabetes mellitus was experimentally induced in groups B and C by a single intra-peritoneal injection of 80mg/kg streptozotocin dissolved in 0.1M citrate buffer. Group A rats were intraperitoneally injected with equivalent volume of citrate buffer. Daily intra peritoneal injection of 100mg/kg A. muricata was administered to group C rats for two weeks. The rats were sacrificed and the pancreas were removed and fixed in Bouins fluid. The tissues were processed for paraffin embedding and sections of 5μm thickness were produced and stained. Histopathological examination of the stained sections showed regeneration β-cells of islets of pancreas of A. muricata-treated rats when compared to untreated diabetic group of rats.
本研究旨在探讨番荔枝叶甲醇提取物对链脲佐菌素诱导的糖尿病大鼠胰岛细胞的影响。将30只成年Wistar大鼠随机分为A、B、C三组,每组10只。A组为对照组,B组为糖尿病未治疗组,C组为木田治疗组。B、C组小鼠腹腔单次注射溶于0.1M柠檬酸缓冲液中的链脲佐菌素80mg/kg诱导糖尿病。A组大鼠腹腔注射等体积的柠檬酸缓冲液。C组大鼠每日腹腔注射村田青100mg/kg,连续2周。处死大鼠,切除胰腺,用Bouins液固定。组织进行石蜡包埋处理,制作厚度为5μm的切片并染色。染色切片的组织病理学检查显示,与未治疗的糖尿病组大鼠相比,木参治疗组大鼠胰腺胰岛有再生β细胞。
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引用次数: 16
How Complementary and Alternative Medicine (CAM) is promoted in Bangladesh?: A Critical Evaluation of the Advertisements Published in Local Newspapers 孟加拉国如何推广补充和替代医学?地方报纸广告的批判性评价
Pub Date : 2007-12-31 DOI: 10.5580/16ff
Mohammad Saidul Islam, S. Farah
Majority of population are still using complementary and alternative medicine (CAM) in Bangladesh. Many of the CAM providers are engaged in the advertising of various remedial methods for numerous diseases in the local newspapers of the country. This exploratory study investigated such advertisements collected from some renowned newspapers of Bangladesh. Most of the advertisements in those newspapers were found to focus mainly on the conditions related to sex and sexuality. Other major manifestations reported were related to psychological, cancers related and gynecological issues. Exaggerated and incongruent treatment claims were very common with 100% money-back treatment guarantee in some advertisements. Homeopathy system claimed to treat all possible cancers of human being. Advertisements of CAM in the newspapers of Bangladesh appear to be misleading, which may have potentials to misdirect patients from seeking better treatment options for their ailments.
孟加拉国大多数人口仍在使用补充和替代医学(CAM)。许多CAM提供者在该国的地方报纸上为许多疾病的各种治疗方法做广告。本探索性研究调查了从孟加拉国一些著名报纸收集的此类广告。这些报纸上的大多数广告主要集中在与性和性有关的情况上。报告的其他主要表现与心理、癌症相关和妇科问题有关。夸大和不一致的治疗主张在一些广告中非常普遍,100%退款保证治疗。顺势疗法声称能治疗人类所有可能的癌症。孟加拉国报纸上CAM的广告似乎具有误导性,这可能会误导患者寻求更好的治疗方案。
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引用次数: 8
Oxidative stress and endogenous antioxidants in normolipidemic Acute Myocardial Infarction patients 正常血脂急性心肌梗死患者的氧化应激和内源性抗氧化剂
Pub Date : 2007-12-31 DOI: 10.5580/1894
Arun Kumar, R. Sivakanesan
Background: Although studies have demonstrated the role of endogenous antioxidants in the protection from the deleterious effects of oxygen free radicals in ischemia and reperfusion, there are controversial data on the correlation between endogenous antioxidants and ischemia process. Aim: The present study was planned to evaluate endogenous antioxidants in normolipidemic acute myocardial infarct (AMI) patients. Setting & Design: The serum lipid profile, albumin, uric acid, total bilirubin, malondialdehyde and conjugated dienes were determined in 165 normolipidemic patients diagnosed of AMI and 165 age-sexes matched healthy volunteers served as control. Material & Methods: Serum albumin was measured by Bromo cresol green (BCG) dye binding method, uric acid was measured by phosphotungstic acid reduction method and serum total bilirubin by Jendrassik and Grof method, serum MDA was measure by MDA method estimating TBARS and conjugated dienes by Recknagel and Glende method (with little modifications) in AMI patients and controls. Also lipid profile was analyzed enzymatically in these subjects. Statistics: The values were expressed as means ± standard deviation (SD) and data from patients and control was compared using student's't'-test. Results And Conclusion: The endogenous antioxidants were significantly decreased (p<0.001) in AMI patients compared to controls. Serum malondialdehyde and conjugated dienes were significantly (p<0.001) increased in AMI patients compared to controls. Also total cholesterol, TC: HDL-C ratio, triglycerides, LDL-cholesterol, LDL-C: HDL-C ratio and TG: HDL-C ratio were higher in AMI subjects (p<0.001) and HDL-cholesterol were lower in AMI subjects (p<0.001).
背景:虽然研究表明内源性抗氧化剂在缺血和再灌注过程中对氧自由基的有害影响具有保护作用,但内源性抗氧化剂与缺血过程的相关性存在争议。目的:本研究旨在评价正常血脂急性心肌梗死(AMI)患者体内的内源性抗氧化剂。背景与设计:测定165例诊断为AMI的正常血脂患者的血脂、白蛋白、尿酸、总胆红素、丙二醛和偶联二烯,165例年龄性别匹配的健康志愿者作为对照。材料与方法:AMI患者和对照组用溴甲酚绿(BCG)染料结合法测定血清白蛋白,用磷钨酸还原法测定尿酸,用Jendrassik和Grof法测定血清总胆红素,用MDA法测定血清中TBARS和偶联二烯(reknagel和Glende法,修改较少)。同时用酶法分析了这些受试者的脂质谱。统计学:数值以均数±标准差(SD)表示,患者与对照组数据采用student's'检验进行比较。结果与结论:AMI患者体内抗氧化剂水平明显低于对照组(p<0.001)。与对照组相比,AMI患者血清丙二醛和共轭二烯显著升高(p<0.001)。AMI组总胆固醇、TC: HDL-C比值、甘油三酯、ldl -胆固醇、LDL-C: HDL-C比值和TG: HDL-C比值较高(p<0.001), hdl -胆固醇较低(p<0.001)。
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引用次数: 3
Gold Seed Implants: An Alternative Acupuncture Treatment 金种子植入:另一种针灸疗法
Pub Date : 2007-12-31 DOI: 10.5580/aeb
Breion Mailloux, J. Feldman
A 43 year old female with multiple sclerosis was treated for approximately ten years, utilizing a specific type of acupuncture therapy. Noted incidentally on hospital admission for pneumonia and urinary tract infection, the gold-seed needle tips were permanently implanted, with the intent of long-term symptom relief. In this case, the patient attributed resolution of her right foot drop to the treatments. CASE REPORT A 43 year old female with multiple sclerosis was treated for approximately ten years, utilizing a specific type of acupuncture therapy. Noted incidentally on hospital admission for pneumonia and urinary tract infection, the gold-seed needle tips were permanently implanted, with the intent of long-term symptom relief. In this case, the patient attributed resolution of her right foot drop to the treatments. Little is written in Western medicine regarding efficacy and possible side effects of such implants. Some Eastern cultures use the technique to treat inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and lupus erythematosus. However, gold compounds are being explored as an alternative option in the management of various other conditions. References 1. Barratt, J., Steer, H., and Onyirioha, T. (2007). Pneumothorax Following Acupuncture. British Journal of Hospital Medicine. 68:667. 2. Qin, W., Tian, J., Pan, X., Yang, L., and Zhen, Z. (2006). The Correlated Network of Acupuncture Effect: A Functional connectivity study. Engineering in Medicine and Biology Society. 28th Annual International Conference of the IEEE. 1:480-483. Gold Seed Implants: An Alternative Acupuncture Treatment 2 of 2 Author Information Breion Mailloux, D.O., MGH Internal Medicine Resident, St. Joseph's Hospital and Medical Center Jeremy Feldman, MD Arizona Pulmonary Specialists, LTD, Pulmonary and Critical Care Medicine, Director, Pulmonary Hypertension Program, Medical Director, Clinical Research
一位患有多发性硬化症的43岁女性接受了大约10年的治疗,使用了一种特定类型的针灸疗法。在住院治疗肺炎和尿路感染时,顺便注意到,金籽针尖被永久植入,目的是长期缓解症状。在本例中,患者将右脚下垂的解决归功于治疗。病例报告一名43岁女性多发性硬化症患者接受了大约10年的治疗,采用了一种特定类型的针灸疗法。在住院治疗肺炎和尿路感染时,顺便注意到,金籽针尖被永久植入,目的是长期缓解症状。在本例中,患者将右脚下垂的解决归功于治疗。西医很少有关于这种植入物的疗效和可能的副作用的记载。一些东方文化使用这种技术来治疗炎症,如类风湿关节炎、炎症性肠病和红斑狼疮。然而,人们正在探索金化合物作为管理各种其他条件的替代选择。引用1。Barratt, J., Steer, H.和Onyirioha, T.(2007)。针刺后气胸。英国医院医学杂志。68:667。2. 秦伟,田军,潘晓燕,杨磊,甄震(2006)。针刺效应的相关网络:功能连通性研究。医学与生物工程学会。第28届IEEE国际年会。1:480 - 483。金种子植入物:替代针灸治疗2 / 2作者信息Breion Mailloux,医学博士,MGH内科住院医师,圣约瑟夫医院和医疗中心杰里米·费尔德曼,医学博士亚利桑那肺部专家,有限公司,肺部和重症监护医学,主任,肺动脉高压项目,医学主任,临床研究
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引用次数: 0
Effects of Naringenin on Lipogenesis, Lipolysis and Glucose Uptake in Rat Adipocyte Primary Culture: A natural antidiabetic agent 柚皮素对大鼠脂肪细胞原代培养脂肪生成、脂肪分解和葡萄糖摄取的影响:一种天然降糖剂
Pub Date : 2007-12-31 DOI: 10.5580/22f3
Siang-Ling Lim, K. Soh, U. Kuppusamy
The flavonoid naringenin is commonly found in citrus fruits and tomato. The main aim of this study was to assess the in vitro insulin-like effects of naringenin using rat adipocyte primary culture. The adipogenic, lipolytic and glucose uptake activities of naringenin in primary rat adipocytes were assessed using Oil Red O, glycerol, and 2-deoxy-D-2,6-3Hglucose uptake quantitative assays respectively. Naringenin exhibited significant increase of lipogenesis in the presence and absence of insulin in primary rat preadipocytes. At the concentration range of 0.01 - 100 µM, naringenin inhibited 50 % of epinephrine induced lipolysis in rat adipocytes and enhanced insulin's antilipolytic activity. Naringenin (100 µM) stimulated 163 % glucose uptake in rat adipocytes (compared to untreated cells) and this was significantly higher than the insulin mediated glucose uptake at similar concentration. Thus, naringenin may play an important role as an adjuvant and/or alternative to insulin therapy for the management of diabetes mellitus. ABSTRACT FROM AUTHOR Copyright of Internet Journal of Alternative Medicine is the property of Internet Scientific Publications LLC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
类黄酮柚皮素通常存在于柑橘类水果和番茄中。本研究的主要目的是利用大鼠脂肪细胞原代培养,评估柚皮素的体外胰岛素样作用。分别采用油红O、甘油和2-脱氧-d -2,6- 3h葡萄糖摄取定量测定法测定柚皮素在大鼠原代脂肪细胞中的成脂、溶脂和葡萄糖摄取活性。柚皮素在大鼠原代前脂肪细胞中表现出胰岛素存在和不存在时脂肪生成的显著增加。在0.01 ~ 100 µM浓度范围内,柚皮素可抑制50%的肾上腺素诱导的大鼠脂肪细胞的脂溶,并增强胰岛素的抗脂溶活性。柚皮素(100 µM)刺激大鼠脂肪细胞163%的葡萄糖摄取(与未处理的细胞相比),显著高于相同浓度下胰岛素介导的葡萄糖摄取。因此,柚皮素可能在糖尿病的治疗中起到辅助和/或替代胰岛素治疗的重要作用。Internet Journal of Alternative Medicine的版权是Internet Scientific Publications LLC的财产,未经版权所有者的书面许可,其内容不得被复制或通过电子邮件发送到多个网站或发布到listserv。但是,用户可以打印、下载或通过电子邮件发送文章供个人使用。这篇摘要可以删节。对副本的准确性不作任何保证。用户应参考资料的原始出版版本以获取完整摘要。(版权适用于所有摘要。)
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引用次数: 9
Role of Homoeopathy in the Management of Autism: Study of Effects of Homoeopathic Treatment on the Autism Triad 顺势疗法在自闭症治疗中的作用:顺势疗法治疗自闭症三联征的效果研究
Pub Date : 2007-12-31 DOI: 10.5580/1008
M. Rajalakshmi
Autism is a disorder with a wide range of severities. The major issues that come up while dealing with autism are in the following areas: Firstly there are the behavioural issues such as hyperactivity, temper tantrums, poor attention span, decreased concentration and poor focusing. Secondly there are the speech, language and communication issues that are a major concern for parents. Thirdly there are the social skills impairment such as poor eye contact and poor interaction with peers. It has been seen that it is not possible to manage the above mentioned problems with just training alone. Learning is not possible when the child is hyperactive or is not able to focus or concentrate. Also the behavioural and communication problems may stem from an internal rather than an external cause that needs to be rectified. In such a situation it has been observed that with homoeopathic treatment the child's understanding, eye contact and in the long run, communication also improve. For example: In one case, a parent mentioned that she was trying to train her son in self care activities that was very tedious, as she had to make him do it step by step and he would forget it immediately. She would then have to repeat the whole process everyday. But after homoeopathic treatment, she just had to ask him to do that activity and he would comply without making any mistakes as his understanding and receptive language skills had improved.
自闭症是一种严重程度很广的疾病。在处理自闭症时出现的主要问题有以下几个方面:首先是行为问题,如多动症、脾气暴躁、注意力持续时间短、注意力不集中和注意力不集中。其次是言语、语言和交流问题,这是父母主要关心的问题。第三是社交技能障碍,如眼神交流和与同龄人互动不良。人们已经看到,仅仅通过训练是不可能解决上述问题的。当孩子过度活跃或不能集中注意力时,学习是不可能的。此外,行为和沟通问题可能源于内部原因,而不是需要纠正的外部原因。在这种情况下,通过顺势疗法治疗,儿童的理解力、眼神接触以及长期的沟通能力也得到了改善。例如:在一个案例中,一位家长提到,她试图训练她的儿子自理活动,这是非常繁琐的,因为她必须让他一步一步地做,他会立即忘记。然后她每天都要重复整个过程。但经过顺势疗法治疗后,她只需要让他做那个活动,他就会听从,不会犯任何错误,因为他的理解和接受语言能力得到了提高。
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引用次数: 6
Estimation of phenolic acids in different preparations of seeds of finger millet (Eleusine coracana):: Their possible implications in human health 五谷籽不同制剂中酚酸的估计:*它们对人体健康的可能影响
Pub Date : 2007-12-31 DOI: 10.5580/d5b
U. P. Singh, S. Maurya, Amitabh Singh, Mandavi Singh
HPLC analysis for phenolic acids of seeds of six varieties (Gaza, KM-252, PES-400, Ranichauri, VL-146, VL-149) and a local variety and their different preparations, i. e., dry, water soaked, cooked seeds, flour and bread of E. coracana indicated that dry seeds of some cultivars are rich in phenolic acids. Variety Ranichauri (Local varieties) and KM-252 had five and four phenolic acids respectively, in which GA was maximum. Gaza, Vl-146 and VL-149 had three phenolic acids in which gallic acid was maximum Water soaked seeds of the above mentioned cultivars gave similar results in which GA was maximum in most of them followed by TA, VA, Chl-A and Caf-A. Water extract of seeds showed several water-soluble phenolic acids such as TA, GA, PCat-A, FA, Chl-A, CA. Among them, P-Cat-A (592.05 μg/g) and FA (147.52 μg/g) were present in good amount. Dry and cooked seeds, extract of boiled seeds, flour and bread also had several phenolic acids in good amount.
HPLC分析了加萨、KM-252、PES-400、Ranichauri、VL-146、VL-149 6个品种和1个地方品种及其不同制剂(干制、水浸、煮熟种子、面粉和面包)种子中的酚酸含量,结果表明,部分品种干制种子中酚酸含量较高。品种Ranichauri(地方品种)和KM-252分别含有5种和4种酚酸,其中GA含量最高。加萨、Vl-146和VL-149的3种酚酸含量最高,其中没食子酸含量最高,上述品种的水浸结果相似,多数品种的GA含量最高,其次是TA、VA、Chl-A和ca - a。种子水提液中含有TA、GA、PCat-A、FA、Chl-A、CA等水溶性酚酸,其中P-Cat-A (592.05 μg/g)和FA (147.52 μg/g)含量较高。干的和煮熟的种子、煮熟的种子提取物、面粉和面包中也含有大量的酚酸。
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引用次数: 2
Evaluation of relationship between the Centella asiatica (Linn) fresh leaf extract induced spatial learning and memory enhancement and increased body weight gain in neonatal and adult rats 积雪草鲜叶提取物诱导新生大鼠和成年大鼠空间学习记忆能力增强与体重增加的关系
Pub Date : 2007-12-31 DOI: 10.5580/1d05
K. Rao, S. Rao, S. Rao
Centella asiatica (CeA) is a plant which grows in damp places in India and other Asian Countries. In Ayurvedic system of medicine, an alternative system of medicine practised mainly in India, leaves of CeA are used along with some other herbs as medhya drugs for memory enhancement and as promoter of strength and digestive power. In the present study, we have tried to establish the relation ship between the two of the properties of this plant. That is, spatial learning and memory enhancing property and its effect on overall body weight growth in neonatal and adult rats. The present study was conducted in neonatal (7day old) and adult (2.5 month old) rats. Both the groups of rats were fed with 2, 4 and 6ml/kg body of fresh leaf extract of CeA for 2, 4 and 6 weeks. During the treatment period the body weight of rats were noted at the end of every week. The body weight gained by the rats was compared with the spatial learning and memory enhancing effects of CeA on these rats reported earlier. The results showed a dose and duration dependent significance increase in the body weight gain in rats treated with CeA. This increase in the body weight was seen only in those groups were there was significant increase in spatial learning performance and enhanced memory retention power. This indicates that, there is a relationship between the spatial learning and memory enhancing effect of CeA and the body weight gain in rats.
积雪草(Centella asiatica, CeA)是一种生长在印度和其他亚洲国家潮湿地区的植物。在阿育吠陀医学体系中,一种主要在印度实践的替代医学体系,CeA的叶子与其他一些草药一起被用作增强记忆和促进力量和消化能力的中草药。在本研究中,我们试图建立这种植物的两种性质之间的关系。即空间学习记忆增强特性及其对新生大鼠和成年大鼠整体体重增长的影响。本研究以新生大鼠(7日龄)和成年大鼠(2.5个月龄)为实验对象。两组大鼠分别以2、4、6ml/kg体重的CeA鲜叶提取物喂养2、4、6周。在给药期间,每周末记录大鼠体重。将大鼠体重增加与CeA对空间学习记忆的增强作用进行比较。结果显示,CeA对大鼠体重增加有剂量依赖性和持续时间依赖性。体重的增加只出现在那些空间学习能力显著提高和记忆力增强的小组中。这说明,CeA对空间学习记忆的增强作用与大鼠体重增加之间存在一定的关系。
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引用次数: 1
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The Internet Journal of Alternative Medicine
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