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Potential Beneficial Effects of Mineral Sunscreens on Acne-Prone Skin 矿物防晒霜对痤疮皮肤的潜在益处
Pub Date : 2024-03-18 DOI: 10.2174/0126667797285930240306190539
Marina Gomes, Fabiana Vieira Lima, Catarina Rosado, B. R. Pezzini
Sunscreens are critical products used against harmful ultraviolet (UV)radiation. However, beyond the effect of sun protection, the inorganic UV filters zinc oxide andtitanium dioxide have shown antimicrobial activity.This study aimed to evaluate the potential additional beneficial effects of mineral sunscreens containing zinc oxide and titanium dioxide as antimicrobial agents on acne-prone skin.Transepidermal water loss, skin hydration, and skin pH of twelve volunteers weremeasured before and 2 h after the application of three mineral sunscreens. The antimicrobial activity of the mineral sunscreens was determined against Cutibacterium acnes, Staphylococcusaureus, and Staphylococcus epidermidis in a time-kill test.The studied mineral sunscreens did not affect either the stratum corneumhydration or its integrity, but they increased the skin pH from 4 to 6, which could impact the skinmicrobiota balance. At the same time, the tested mineral sunscreens inhibited Cutibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus.This study suggests that the two UV filters can have positive effects on acne-proneskin and, thus, extend the benefits of photoprotective formulations. Nevertheless, further researchis currently being conducted.
防晒霜是抵御有害紫外线(UV)辐射的重要产品。本研究旨在评估含有氧化锌和二氧化钛的矿物防晒霜作为抗菌剂对痤疮皮肤可能产生的额外有益影响。研究人员在使用三种矿物防晒霜之前和之后 2 小时测量了 12 名志愿者的经表皮失水率、皮肤水合作用和皮肤 pH 值。在时间致死试验中测定了矿物防晒霜对痤疮杆菌、金黄色葡萄球菌和表皮葡萄球菌的抗菌活性。这项研究表明,这两种紫外线过滤剂可以对痤疮皮肤产生积极影响,从而扩大光防护配方的功效。不过,目前还在进行进一步的研究。
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引用次数: 0
Exploring the Application of Artificial Intelligence in Cosmetics andBeauty Industry 探索人工智能在化妆品和美容业中的应用
Pub Date : 2024-02-28 DOI: 10.2174/0126667797280144240221055142
Harshita Mathur, Anurag Chaudhary, Devkant Sharma, Alok Sharma
The present work highlights how AI can enhance the personalized cosmetic experiencebased on the digitalization of make-up by consumers, the selection of perfect product characteristicsand optimization of new cosmetic products on the basis of big data. Moreover, the differentAI technologies applied in cosmetics have also been presented in a concise manner. Cosmeticcompanies are advancing and are expected to be even more advanced in the future. The presentwork could provide a new direction in the development of an AI algorithm approach for cosmeticcompanies’ development and for building a database for cosmetic applications.
本作品重点介绍了人工智能如何在消费者化妆数字化、选择完美产品特性和基于大数据优化新化妆品的基础上,提升个性化化妆品体验。此外,本文还简明扼要地介绍了应用于化妆品的各种人工智能技术。化妆品公司正在不断进步,预计未来会更加先进。本研究可为化妆品公司开发人工智能算法方法和建立化妆品应用数据库提供新的方向。
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引用次数: 0
Cosmetic Science Applied to Dentistry and Teeth: An Analytical Appraisal 应用于牙科和牙齿的美容科学:分析评估
Pub Date : 2024-01-12 DOI: 10.2174/0126667797278318240110110645
Louis Z.G. Touyz
The term cosmetics conventionally encompasses the application of beautifyingproducts and processes for skin and may also be applied to teeth. Although cosmetic dentistrystrives to produce immediate amelioration of appearance, it is not durable, can invoke undesirabletissue reactions, may be gratuitously decorative, may not be ideally functional andcould have compromising results. There are differences between cosmetic and esthetic dentistry.This appraisal re-affirms differences between them and provides examples to illustratedifferences.
化妆品一词通常包括用于美化皮肤的产品和工艺,也可用于牙齿。虽然美容牙科致力于立即改善外观,但它并不持久,可能会引起不良的组织反应,可能是无偿的装饰,可能不是理想的功能,并可能产生损害的结果。美容牙科和美学牙科之间是有区别的,本评估重申了两者之间的区别,并举例说明了两者之间的区别。
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引用次数: 0
Determining Anti-acne Potential of Azadirachta Indica Leaf Powder, Herbal Hydrogel using s. Aureus Growth Inhibition Model, by Agar Well Diffusion Technique 利用琼脂阱扩散技术,采用金黄色葡萄球菌生长抑制模型测定印度杜鹃叶粉和草本水凝胶的抗痤疮潜力
Pub Date : 2023-12-20 DOI: 10.2174/0126667797276773231215053914
Harish Kumar, Madhu Verma, Harshit Garg, Ishu Garg, Ishika Sharma
Neem (Azadirachta indica) can be considered as a boon to mankind as it possesses innumerable medicinal benefits despite being cost effective. Its use as an anti-acne agent is widely anticipated. A topical formulation of neem leaf powder as hydrogel was prepared recognizing the use of its phytoconstituents in many skin therapies. The primary goal of topical formulations is to provide drug contact with the skin while reducing overall absorption. The aim of this study was to evaluate the anti-acne potential of Neem leaves powder hydrogel. Neem powder was tested for its organoleptic and physical characteristics. Neem hydrogel was prepared in a 1% w/v carbopol gel and evaluated by agar disk diffusion. A 3% w/w (F1) and 2% w/w (F2) hydrogel prepared by adding 3g and 2g, respectively, to the prepared carbopol gel making a volume of 100 ml, was evaluated for various parameters. A comparative evaluation tests were conducted for F1, F2 and 1% w/v carbopol gel (blank). After the test results, F1 was optimized for pH and viscosity by adding triethanolamine. Optimized F1 was tested against 1% w/w salicylic acid gel, and Zitcare-S (Standard) for anti-acne activity. Agar plates were prepared and a well was dug using a borer. The wells were filled with the F1, standard and blank, inoculated by the Staphylococcus aureus using the spread culture technique. The plates were incubated for 24 hours at standard conditions. F1, F2, blank and standard were tested for their viscosity, spreadability, pH and some organoleptic parameters. The test results from F1 and F2 suggested F1 to be a more efficient hydrogel. Standard, blank and F1 were tested using agar well diffusion technique. After the incubation period, the plates were taken out and kept on a white sheet. Using a meter scale, the radius of the zone of inhibition was determined. It was found that F1 gave 1.7cm, standard gave 1.3cm and blank gave 0cm radius size zone of inhibition. Test results suggest that F1 has better spreadability and viscosity in comparison to F2. This study concludes that F1 is a more stable and efficient formulation as a hydrogel with efficient spreadability and optimum viscosity. F1 has better anti-bacterial activity than the standard and has better anti-acne potential.
印度楝树(Azadirachta indica)可以说是人类的福音,因为它具有无数的药用价值,而且成本低廉。人们普遍期待它能用作抗痤疮剂。考虑到楝树叶粉末的植物成分可用于多种皮肤疗法,我们制备了一种楝树叶粉末水凝胶外用配方。外用制剂的主要目的是让药物与皮肤接触,同时减少整体吸收。 本研究旨在评估印度楝树叶粉水凝胶的抗痤疮潜力。 测试了楝树叶粉末的感官和物理特性。在含水量为 1%/v 的 carbopol 凝胶中制备了楝树叶水凝胶,并通过琼脂盘扩散法进行了评估。在配制好的体积为 100 毫升的 carbopol 凝胶中分别加入 3 克和 2 克配制成的 3% w/w 水凝胶(F1)和 2% w/w 水凝胶(F2)进行了各种参数评估。对 F1、F2 和 1% w/v carbopol 凝胶(空白)进行了比较评估试验。测试结果出来后,通过添加三乙醇胺对 F1 的 pH 值和粘度进行了优化。优化后的 F1 与 1% w/w 水杨酸凝胶和 Zitcare-S(标准)进行了抗痤疮活性测试。制备琼脂平板,用钻孔器挖孔。在孔中分别填入 F1、标准和空白,用扩散培养技术接种金黄色葡萄球菌。平板在标准条件下培养 24 小时。 对 F1、F2、空白和标准进行粘度、铺展性、pH 值和一些感官参数的测试。F1 和 F2 的测试结果表明 F1 是一种更有效的水凝胶。标准品、空白品和 F1 采用琼脂井扩散技术进行测试。培养期结束后,取出平板放在白纸上。用刻度尺测定抑制区的半径。结果发现,F1 的抑菌半径为 1.7 厘米,标准抑菌半径为 1.3 厘米,空白抑菌半径为 0 厘米。 试验结果表明,与 F2 相比,F1 具有更好的铺展性和粘度。本研究得出结论:F1 是一种更稳定、更有效的水凝胶配方,具有高效的铺展性和最佳粘度。F1 的抗菌活性优于标准配方,而且具有更好的抗痤疮潜力。
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引用次数: 0
Facial Exercises: Enhancing Facial Structure and Reducing Signs of Aging:A Comprehensive Review 面部运动:面部运动:改善面部结构,减少衰老迹象:全面回顾
Pub Date : 2023-12-18 DOI: 10.2174/0126667797268583231213112215
Andreza Sonego Furlan, Mariane Massufero Vergilio, C. Vendruscolo, G. Leonardi
The effectiveness of facial muscle exercises (FMEs) for facial rejuvenation is still quitecontroversial in the scientific literature. In general, published studies use non-quantitative parametersto assess the real benefit of FMEs. In this study, we reviewed the scientific evidence relatedto the efficacy of FMEs for facial rejuvenation, as well as to describe the most used FMEs inscientific studies. To achieve the objective of this review, research was performed through severaldatabases. Thus far, there are very few scientific studies with appropriate methodologies that assesswhether FMEs are effective for facial rejuvenation. It was found that the exercises for themuscles of the cheeks, the region around the mouth and around the eyes, and the region under thechin are the most indicated for the maintenance of the youthful appearance of the face. However,it is still necessary to carry out controlled and randomized studies to draw some conclusions.
在科学文献中,面部肌肉锻炼(FMEs)对面部年轻化的有效性仍存在争议。一般来说,已发表的研究使用非定量参数来评估面部肌肉运动的实际效果。在这项研究中,我们回顾了与面部年轻化效果相关的科学证据,并描述了科学研究中使用最多的面部年轻化设备。为了达到本综述的目的,我们通过多个数据库进行了研究。到目前为止,很少有科学研究采用适当的方法来评估 FMEs 对面部年轻化是否有效。研究发现,脸颊肌肉、嘴角和眼睛周围区域以及下巴区域的锻炼对保持面部年轻外观最有效。不过,仍有必要进行对照和随机研究,以得出一些结论。
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引用次数: 0
Development of Aged Skin Equivalent Model 老化皮肤等效模型的开发
Pub Date : 2023-12-04 DOI: 10.2174/0126667797269907231118130449
L. M. Brand, M. Lamers, Bibiana Franzen
Skin aging is a result of the aging process and also intrinsic and extrinsicfactors. In order to better understand this process and evaluate anti-aging products, it is necessaryto develop in vitro models that can recapitulate the biological process of aged skin. Therefore, theaim of this study was to develop an aged skin equivalent model to evaluate these properties.Human fibroblasts were incorporated into the collagen matrix and keratinocytes wereadded and cultured in an air-liquid interface for 21 days. During this period, the matrices wereexposed to UV or EX527 to trigger biological aging processes.The two protocols evaluated demonstrated reduced expression of genes related to longevity and regulation of cellular redox homeostasis, and it was confirmed with histological analysis. Also, the model demonstrated the anti-aging potential of resveratrol.The model developed is a promising platform for reproducing aged skin and evaluating rejuvenating agents.
皮肤老化是衰老过程的结果,也是内在和外在因素共同作用的结果。为了更好地了解这一过程并评估抗衰老产品,有必要开发能够概括皮肤衰老生物过程的体外模型。因此,本研究的目的是建立一个老化皮肤等效模型来评估这些特性。将人成纤维细胞掺入胶原基质中,加入角质形成细胞,在气液界面培养21天。在此期间,将基质暴露于UV或EX527中以触发生物老化过程。评估的两种方案表明,与寿命和细胞氧化还原稳态调节相关的基因表达减少,并通过组织学分析得到证实。此外,该模型还显示了白藜芦醇的抗衰老潜力。所建立的模型是一个很有前途的平台,用于再生老化皮肤和评估恢复活力的药物。
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引用次数: 0
Herbs as Hair Care Cosmetic Agents: Mini Review 草药作为头发护理化妆品剂:迷你评论
Pub Date : 2023-11-10 DOI: 10.2174/0126667797260283231004080654
Sanket Vakte, Yash Mahajan, Neeraj Lohagaonkar, Ramdas Dolas, Abhijeet Kulkarni, Subodh Gangurde, Pravin Jha, Vivek Byahatti, Makarand Gambhire
Abstract: Healthy hair is an important part of a beautiful body. Thus, new developments in hair science and hair care have been reported in the literature, and innovations and ideas in hair care and cosmetics are required. Hair care products are used to keep the scalp clean and moisturize the hair. Hair care products also help control hair structure and behavior, keeping hair in a controlled environment if necessary. Natural cosmetics are safer to use when compared with other synthetic products. They are hypoallergenic, dermatologist-tested and proven to be safe to use anytime, anywhere. Hair cosmetics consist of different agents such as hair oil, hair tonic, anti-dandruff, hair dye, etc. This review focuses on different types of herbs that can be used cosmetically for hair care.
摘要:健康的头发是美丽身体的重要组成部分。因此,文献报道了头发科学和头发护理的新发展,并且需要头发护理和化妆品的创新和想法。护发产品用于保持头皮清洁和滋润头发。护发产品也有助于控制头发的结构和行为,在必要时将头发保持在可控的环境中。与其他合成产品相比,天然化妆品更安全。他们是低过敏性,皮肤科医生测试,并证明是安全的,随时随地使用。头发化妆品由发油、护发液、去屑剂、染发剂等不同的药剂组成。这篇综述的重点是不同类型的草药,可以用于美容头发护理。
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引用次数: 0
How to Choose the Best Fragrance for Your Cosmetics 如何为你的化妆品选择最好的香水
Pub Date : 2023-11-09 DOI: 10.2174/0126667797268443231102065235
Sakshi Minocha
Background: Some people may experience allergic responses like skin irritation and rashes due to the seductive aroma of your attractive cosmetic products. The fragrance in your cosmetic items can also lead to serious allergies like asthma and headaches, which may deter customers from purchasing your cosmetics. The development of fragrances is a crucial component of cosmetic formulation because it blends an aesthetic vision with knowledge of the chemistries and dynamics of the scent materials. Objective: When launching a cosmetics company and having a product ready to sell, it is crucial to take into account a number of elements, including the potency of the scent, the product's stability in the presence of heat and light, the compatibility of the ingredients, and the effects of the packaging. While certain compounds used in fragrances quickly disappear from the skin, others cling to it for longer. In order to accomplish the intended outcome and produce a product that is attractive to the eye, it is crucial for these qualities to interact over time. Buyer psychology is impacted by fragrance in cosmetic products, which may influence whether or not a consumer decides to purchase it. Methods: The study utilized a comprehensive review of existing literature, market research, and industry insights to gather information on fragrance selection for cosmetics. Results: The results of the study indicate that choosing the best fragrance for cosmetics involves considering several key factors. Firstly, understanding the specific product type is crucial, as different cosmetics require different types of fragrances to match their purpose and intended use. Secondly, considering the target audience's preferences is essential, as different demographics have varying fragrance preferences. Thirdly, aligning the fragrance with the brand identity is important to create a cohesive and consistent product experience. Conclusion: In conclusion, selecting the best fragrance for cosmetics requires a thoughtful and strategic approach. By considering the product type, target audience, brand identity, and market trends, cosmetics manufacturers can make informed decisions that enhance the overall product experience and customer satisfaction.
背景:有些人可能会经历过敏反应,如皮肤刺激和皮疹,由于你的诱人的化妆品的诱人的香气。化妆品中的香味也会导致严重的过敏,比如哮喘和头痛,这可能会阻止顾客购买你的化妆品。香水的开发是化妆品配方的一个重要组成部分,因为它将美学视觉与气味材料的化学和动力学知识结合在一起。目标:当成立一家化妆品公司并准备销售产品时,考虑到许多因素是至关重要的,包括气味的效力,产品在热和光存在下的稳定性,成分的相容性以及包装的效果。虽然香水中使用的某些化合物会很快从皮肤上消失,但其他化合物会附着在皮肤上更长时间。为了达到预期的效果,生产出吸引眼球的产品,这些品质随着时间的推移相互作用是至关重要的。化妆品中的香味会影响购买者的心理,从而影响消费者是否购买化妆品。方法:该研究利用现有文献,市场调查和行业见解的综合审查,以收集信息的香水选择化妆品。结果:研究结果表明,为化妆品选择最佳香水需要考虑几个关键因素。首先,了解具体的产品类型是至关重要的,因为不同的化妆品需要不同类型的香水来匹配它们的用途和预期用途。其次,考虑目标受众的偏好是必不可少的,因为不同的人口统计数据有不同的香水偏好。第三,将香水与品牌标识结合起来对于创造一种有凝聚力和一致性的产品体验很重要。结论:总之,为化妆品选择最好的香水需要深思熟虑和策略。通过考虑产品类型、目标受众、品牌标识和市场趋势,化妆品制造商可以做出明智的决定,提高整体产品体验和客户满意度。
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引用次数: 0
Validation of Bioprinting Technique for Skin Equivalent Models 皮肤等效模型生物打印技术的验证
Pub Date : 2023-10-26 DOI: 10.2174/0126667797250440231001193020
Luiza Meurer Brand, Marcelo Lazzaron Lamers, Bibiana Franzen Matte
Background: Skin pigmentation is a complex process; thus, skin equivalent methodologies that can reproduce the main skin structures and pigmentation have been studied. To improve the skin equivalent model, bioprinting technology has emerged, allowing for the reproduction of the complex, functional, and personalized three-dimensional architecture of the skin. Objective: Our aim was to develop a skin equivalent model and a pigmented skin equivalent model and compare the manually produced models with the bioprinted models. Methods: The study was conducted using fibroblasts, keratinocytes, and melanocytes cell lines with a 3D cell culture technique, either through bioprinting or manual production. Additionally, the bleaching potential of the model was evaluated by applying kojic acid. Results: It was observed that the bioprinted skin equivalent model demonstrated similar cell architecture and gene expression compared to the manually produced model. A pigmented skin equivalent model was developed and also bioprinted. The pigmented bioprinted skin equivalent model exhibited similar pigmentation behavior and lightening potential as the manual model. Conclusion: We have validated the use of bioprinting for reproducing skin equivalent model and cost-effective scaling of skin production.
背景:皮肤色素沉着是一个复杂的过程;因此,可以重现主要皮肤结构和色素沉着的皮肤等效方法已经被研究。为了改进皮肤等效模型,生物打印技术已经出现,允许复制皮肤的复杂,功能和个性化的三维结构。目的:建立皮肤等效模型和色素皮肤等效模型,并将人工制作的模型与生物打印的模型进行比较。方法:采用生物打印或手工制作的3D细胞培养技术,使用成纤维细胞、角化细胞和黑素细胞细胞系进行研究。此外,用曲酸对模型的漂白电位进行了评价。结果:观察到生物打印的皮肤等效模型与手工制作的模型具有相似的细胞结构和基因表达。开发了色素皮肤等效模型并进行了生物打印。色素生物打印皮肤等效模型表现出与手工模型相似的色素沉着行为和浅化潜力。结论:我们已经验证了使用生物打印技术复制皮肤等效模型和具有成本效益的皮肤生产规模。
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引用次数: 0
Empowering Consumers: The Evolving Paradigm of Customization in Personal Care Products 赋予消费者权力:个人护理产品定制的演变范式
Pub Date : 2023-10-20 DOI: 10.2174/0126667797265268231011103859
Uday Bhosale, Sridevi Gaddam, Harish Koutam, Prajkta Sapre, Chaitanya Nallan, Shoaeb M Syed
Abstract: Personal care products available in the market are typically designed for the general population, assuming they will be suitable for the majority of consumers. However, customization challenges this notion by focusing on developing products tailored to individual needs, preferences, and unique factors, such as seasonal variations and geographical demands. It acknowledges that people may respond diversely to the same product. Customization in personal care products entails the ability to tailor products to an individual's specific requirements, such as their skin type, hair type, fragrance preferences, etc. Other preferences include geographical requirements like climate, UV exposure, and cultural preferences, along with seasonal changes like winter, monsoon, summer, spring, and fall. The entire experience, including packaging, is personalized. Currently, personal care products represent a relatively small portion, accounting for approximately 10-15% of the overall market, with non-customized products comprising 85-90%. However, recent data suggests that customization is growing at an annual rate of 15.3%, and it is projected to surpass non-customized products by 2031. Customization offers several advantages, including a better fit for consumers' physical and mental health, targeted solutions for specific issues, and increased efficacy. Leading brands in customized personal care products have span different regions worldwide. For instance, SkinCeuticals, an American brand, offers customized skincare products tailored to address individual skin concerns and needs. In India, Vedix and SkinKraft from IncNut Life Style are pioneering brands that provide customized personal care products based on an individual's skin and hair type, along with a Prakriti analysis. These brands offer direct-to-consumer services and are headquartered in Hyderabad, India. The demand for customized personal care products is rapidly increasing worldwide. Beyond individual needs and preferences, further development is required to cater to seasonal and geographical requirements, enabling the creation of more effective products.
摘要:市场上的个人护理产品通常是为一般人群设计的,假设它们适合大多数消费者。然而,定制挑战了这一概念,专注于开发针对个人需求、偏好和独特因素(如季节变化和地理需求)量身定制的产品。它承认人们对同一种产品的反应可能不同。个人护理产品的定制需要根据个人的具体要求定制产品,比如他们的皮肤类型、头发类型、香水偏好等。其他偏好包括地理要求,如气候、紫外线照射和文化偏好,以及季节变化,如冬季、季风、夏季、春季和秋季。整个体验,包括包装,都是个性化的。目前,个人护理产品所占比例相对较小,约占整体市场的10-15%,非定制产品占85% -90%。然而,最近的数据显示,定制产品正以每年15.3%的速度增长,预计到2031年,它将超过非定制产品。定制提供了几个优势,包括更适合消费者的身心健康,针对特定问题的有针对性的解决方案,以及提高功效。定制个人护理产品的领先品牌遍布全球不同地区。例如,美国品牌SkinCeuticals提供针对个人皮肤问题和需求量身定制的护肤产品。在印度,来自IncNut Life Style的Vedix和SkinKraft是基于个人皮肤和头发类型以及Prakriti分析提供定制个人护理产品的先驱品牌。这些品牌提供直接面向消费者的服务,总部设在印度海得拉巴。在全球范围内,对定制个人护理产品的需求正在迅速增长。除了个人需求和偏好之外,还需要进一步发展以满足季节和地理要求,从而能够创造更有效的产品。
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引用次数: 0
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Current Cosmetic Science
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