Pub Date : 2023-08-04DOI: 10.2174/2405461508666230804102333
M. Alam, Aditya Sharma, Awaneet Kaur
There are several safeguards in place to protect the brain from injury because of its vulnerability. Two major barriers prevent harmful substances from entering the brain: the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). Although there has been some success in devising ways for transporting medicines to the brain, the great majority of the nanoparticles (NPs) used in these procedures are destroyed in the process. An awareness of the whole scope of the delivery process and the numerous obstacles it may offer is necessary for the sensible design of brain-targeted pharmaceutical delivery systems. The blood-brain barrier (BBB) is the best-known physiological barrier affecting both brain access and the efficacy of various pharmacological therapies. Accordingly, the development of a promising therapy for the treatment of brain disorders requires drug targeting of the brain, specifically damaged cells. Researchers are looking into nano-carrier systems, also called surface-modified target-specific novel carrier systems, to determine if they can be used to boost the effectiveness of brain drugs while minimizing their side effects. These strategies have the potential to bypass BBB function, leading to increased drug levels in the brain. Numerous physiological parameters, such as active efflux transport, the brain's protein corona, nanocarrier stability and toxicity, physicochemical features, patient-related factors, and others, determine whether or not a novel carrier system is functional.
{"title":"Implementation of Nanocarriers for Brain-Specific Drug Delivery System","authors":"M. Alam, Aditya Sharma, Awaneet Kaur","doi":"10.2174/2405461508666230804102333","DOIUrl":"https://doi.org/10.2174/2405461508666230804102333","url":null,"abstract":"\u0000\u0000There are several safeguards in place to protect the brain from injury because of its vulnerability. Two major barriers prevent harmful substances from entering the brain: the blood-brain barrier\u0000(BBB) and the blood-cerebrospinal fluid barrier (BCSFB). Although there has been some success in\u0000devising ways for transporting medicines to the brain, the great majority of the nanoparticles (NPs)\u0000used in these procedures are destroyed in the process. An awareness of the whole scope of the delivery\u0000process and the numerous obstacles it may offer is necessary for the sensible design of brain-targeted\u0000pharmaceutical delivery systems. The blood-brain barrier (BBB) is the best-known physiological barrier affecting both brain access and the efficacy of various pharmacological therapies. Accordingly,\u0000the development of a promising therapy for the treatment of brain disorders requires drug targeting of\u0000the brain, specifically damaged cells. Researchers are looking into nano-carrier systems, also called\u0000surface-modified target-specific novel carrier systems, to determine if they can be used to boost the\u0000effectiveness of brain drugs while minimizing their side effects. These strategies have the potential to\u0000bypass BBB function, leading to increased drug levels in the brain. Numerous physiological parameters, such as active efflux transport, the brain's protein corona, nanocarrier stability and toxicity, physicochemical features, patient-related factors, and others, determine whether or not a novel carrier system is functional.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44436063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.2174/240546150802221213095311
Khalil Abdelrazek K. Abdelmawgoud
{"title":"Meet the Section Editor","authors":"Khalil Abdelrazek K. Abdelmawgoud","doi":"10.2174/240546150802221213095311","DOIUrl":"https://doi.org/10.2174/240546150802221213095311","url":null,"abstract":"","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134983109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.2174/2405461508666230801095201
Sumbul Shadab, M. Alam, P. Sharma, D. Paliwal
One of the difficult areas of pharmaceutical research is the controlled delivery of drugs to the eye. The drainage of the solution, the quick turnover of the tears, and the diluting effects of lacrimation all contribute to a short drug contact time and poor ocular bioavailability with conventional systems. Drug delivery system design is also governed by the eye's anatomical barriers and its physiological conditions. To prevent retinal uptake of drugs given systemically, the blood-retinal barrier (BRB) has tight junctions that block drug entry. It has been discovered that conventional ophthalmic dosage forms can be avoided along with the problems they cause by using nanocarriers. There are a variety of nanosized carriers available for this purpose, including liposomes, niosomes, polymeric micelles, Nanocarrier-loaded gels, Solid Lipid Nanoparticles (SLNs), polymeric nanoparticles, and dendrimers. This review gives a resume of the different parts of ocular delivery, with a focus on nanocarrier-based strategies, such as delivery routes and the challenges and limits of making new nanocarriers.
{"title":"Overcoming The Therapeutic Limitation of Ocular Drug Delivery with The Help of Novel Drug Carriers","authors":"Sumbul Shadab, M. Alam, P. Sharma, D. Paliwal","doi":"10.2174/2405461508666230801095201","DOIUrl":"https://doi.org/10.2174/2405461508666230801095201","url":null,"abstract":"\u0000\u0000One of the difficult areas of pharmaceutical research is the controlled delivery of drugs to the eye. The drainage of the solution, the quick turnover of the tears, and the diluting effects of lacrimation all contribute to a short drug contact time and poor ocular bioavailability with conventional systems. Drug delivery system design is also governed by the eye's anatomical barriers and its physiological conditions. To prevent retinal uptake of drugs given systemically, the blood-retinal barrier (BRB) has tight junctions that block drug entry. It has been discovered that conventional ophthalmic dosage forms can be avoided along with the problems they cause by using nanocarriers. There are a variety of nanosized carriers available for this purpose, including liposomes, niosomes, polymeric micelles, Nanocarrier-loaded gels, Solid Lipid Nanoparticles (SLNs), polymeric nanoparticles, and dendrimers. This review gives a resume of the different parts of ocular delivery, with a focus on nanocarrier-based strategies, such as delivery routes and the challenges and limits of making new nanocarriers.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48638887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-26DOI: 10.2174/2405461508666230726163944
N. Minocha, Meenakshi Attri, A. Raghav, K. Rao, P. Pandey
A lot of work has been done by many researchers to develop a system that is targeted at a specific site. Nanosponges are one of the systems that serve this purpose and have several advantages over other methods. The article’s strategy is to provide access to data regarding the nanosponges system, including its preparation, evaluation, and advantages in various fields, such as the transportation of proteins, vaccines, biocatalysts, and drugs with enhanced bioavailability. Nanosponges also contribute significantly to the treatment of breast cancer, lung cancer, fungal infection, water treatment, and topical application than other approaches. Nanosponges contain a solid, porous system in which hydrophilic or lipophilic drugs are loaded at their core in the nanocavity. All the information provided in this article was collected after analysing various reports on nanosponges available on Google Scholar, PubMed, Scopus, Web of Science, and Science Direct. It is concluded that the nanosponges have excellent aqueous solubility properties. Therefore, they can be used as carriers for drugs with poor water solubility. Moreover, greater bioavailability can be achieved by using the nanosponge approach. Nanosponges possess various outstanding properties that form the unique system of this approach. Nanosponges provide an effective carrier system for enzymes, proteins, vaccines, and therapeutic fields. This review provides a broad overview of the development of nanosponges, their evaluation, and the uses of nanosponges based on cyclodextrin for drug delivery.
许多研究人员已经做了大量的工作来开发一个针对特定地点的系统。纳米海绵是实现这一目的的系统之一，与其他方法相比具有几个优势。这篇文章的策略是提供有关纳米池系统的数据，包括其制备、评估和在各个领域的优势，如蛋白质、疫苗、生物催化剂和生物利用度提高的药物的运输。与其他方法相比，纳米海绵对乳腺癌症、癌症、真菌感染、水处理和局部应用的治疗也有显著贡献。纳米海绵包含一个固体多孔系统，在该系统中，亲水或亲脂性药物被装载在纳米腔的核心。本文中提供的所有信息都是在分析了Google Scholar、PubMed、Scopus、Web of Science和Science Direct上关于纳米池的各种报告后收集的。结果表明，纳米池具有良好的水溶性。因此，它们可以用作水溶性差的药物的载体。此外，使用纳米池方法可以获得更大的生物利用度。纳米海绵具有各种突出的特性，形成了这种方法的独特系统。纳米海绵为酶、蛋白质、疫苗和治疗领域提供了有效的载体系统。这篇综述对纳米囊的开发、评估以及基于环糊精的纳米囊在药物递送中的应用进行了广泛的综述。
{"title":"A Review on Nanosponges: An Idiosyncratic Approach for Delivery of Proactive Molecules","authors":"N. Minocha, Meenakshi Attri, A. Raghav, K. Rao, P. Pandey","doi":"10.2174/2405461508666230726163944","DOIUrl":"https://doi.org/10.2174/2405461508666230726163944","url":null,"abstract":"\u0000\u0000A lot of work has been done by many researchers to develop a system that is targeted at a specific site. Nanosponges are one of the systems that serve this purpose and have several advantages over other methods.\u0000\u0000\u0000\u0000The article’s strategy is to provide access to data regarding the nanosponges system, including its preparation, evaluation, and advantages in various fields, such as the transportation of proteins, vaccines, biocatalysts, and drugs with enhanced bioavailability. Nanosponges also contribute significantly to the treatment of breast cancer, lung cancer, fungal infection, water treatment, and topical application than other approaches.\u0000\u0000\u0000\u0000Nanosponges contain a solid, porous system in which hydrophilic or lipophilic drugs are loaded at their core in the nanocavity. All the information provided in this article was collected after analysing various reports on nanosponges available on Google Scholar, PubMed, Scopus, Web of Science, and Science Direct. It is concluded that the nanosponges have excellent aqueous solubility properties. Therefore, they can be used as carriers for drugs with poor water solubility. Moreover, greater bioavailability can be achieved by using the nanosponge approach.\u0000\u0000\u0000\u0000Nanosponges possess various outstanding properties that form the unique system of this approach. Nanosponges provide an effective carrier system for enzymes, proteins, vaccines, and therapeutic fields. This review provides a broad overview of the development of nanosponges, their evaluation, and the uses of nanosponges based on cyclodextrin for drug delivery.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49647228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-17DOI: 10.2174/2405461508666230717100734
H. Aldosari, N. Madkhali, Saja Algasser, M. Khairy
The attached oxygen functional group in graphene oxide (GO) with layers that are about 1.1 ± 0.2 nm thick, has hindered the performance of electrical characteristics. Diminution of the oxygen functional group, and increasing the carbon/oxygen (C/O) ratio can enhance electrical conductivity. This study investigated the effect of graphene derivatives (C/O) ratios on the dielectric properties of low-density polyethylene (PE) made of metallocene, as well as polypropylene (PP) and mixtures of them. The oxygen functional groups were reduced by utilizing graphene oxide (GO) and reduced graphene oxide (rGO). The effect of GO and rGO-based polyolefin produced by solution blending while lowering the oxygen functional group is explored. The surface morphology and chemical structure were examined by using a scanning electron microscope (SEM) and Fourier Transformed Infrared Spectroscopy (FTIR). The electrical characteristics of the composite films, such as their loss factor (tan δ) and dielectric constant, permittivity and conductivity, and imaginary permittivity were examined. At room temperature, measurements were performed at frequencies ranging from 300 Hz to 8 MHz. ε^'; the dielectric permittivity and imaginary permittivity (ε^'') of polymer/ reduced graphene oxidehowever, these values rapidly decreased with increasing frequency. The alternating current conductivity of the composites was likewise shown to increase with increasing frequency.
{"title":"Progress on Polyolefin/Graphene Nanocomposites with high dielectric constant and low dielectric loss for electrical applications","authors":"H. Aldosari, N. Madkhali, Saja Algasser, M. Khairy","doi":"10.2174/2405461508666230717100734","DOIUrl":"https://doi.org/10.2174/2405461508666230717100734","url":null,"abstract":"\u0000\u0000The attached oxygen functional group in graphene oxide (GO) with layers that are about 1.1 ± 0.2 nm thick, has hindered the performance of electrical characteristics. Diminution of the oxygen functional group, and increasing the carbon/oxygen (C/O) ratio can enhance electrical conductivity.\u0000\u0000\u0000\u0000This study investigated the effect of graphene derivatives (C/O) ratios on the dielectric properties of low-density polyethylene (PE) made of metallocene, as well as polypropylene (PP) and mixtures of them. The oxygen functional groups were reduced by utilizing graphene oxide (GO) and reduced graphene oxide (rGO). The effect of GO and rGO-based polyolefin produced by solution blending while lowering the oxygen functional group is explored.\u0000\u0000\u0000\u0000The surface morphology and chemical structure were examined by using a scanning electron microscope (SEM) and Fourier Transformed Infrared Spectroscopy (FTIR). The electrical characteristics of the composite films, such as their loss factor (tan δ) and dielectric constant, permittivity and conductivity, and imaginary permittivity were examined. At room temperature, measurements were performed at frequencies ranging from 300 Hz to 8 MHz. ε^'; the dielectric permittivity and imaginary permittivity (ε^'') of polymer/ reduced graphene oxidehowever, these values rapidly decreased with increasing frequency.\u0000\u0000\u0000\u0000The alternating current conductivity of the composites was likewise shown to increase with increasing frequency.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43233263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-06DOI: 10.2174/2405461508666230606124615
Hadir Ebraheem, Heba Kahil, Ismail Abd El-Rahim Ali
Magnetite is the most recognized iron oxide candidate used for various biological applications. This work is a complete study that addresses the synthesis of magnetic nanoparticles and investigates the feasibility of using green tea and ascorbic acid as capping agents. Synthesis of magnetite by two wet chemical methods namely: coprecipitation and solvothermal methods. The samples were characterized using X-ray diffraction (XRD), transmission electron microscope (TEM), and vibrating sample magnetometer (VSM). The results reveal the impact of coating on the size and morphology of the particles. The study also proves that autoclaving the samples prepared by coprecipitation results in smaller particle size and narrower size distribution due to digestive ripening. In addition, a novel and facile methodology for coating magnetite with polyethylene glycol is presented. The potential of the particles to be used for magnetic fluid hyperthermia is assessed by measuring the specific absorption rate (SAR) of the samples. The results show that all the prepared magnetite samples showed a promising capacity to be used as magnetic fluid hyperthermia agents.
{"title":"Green Capping Agents and Digestive Ripening for Size Control of Magnetite for Magnetic Fluid Hyperthermia","authors":"Hadir Ebraheem, Heba Kahil, Ismail Abd El-Rahim Ali","doi":"10.2174/2405461508666230606124615","DOIUrl":"https://doi.org/10.2174/2405461508666230606124615","url":null,"abstract":"\u0000\u0000Magnetite is the most recognized iron oxide candidate used for various biological applications.\u0000\u0000\u0000\u0000This work is a complete study that addresses the synthesis of magnetic nanoparticles and investigates the feasibility of using green tea and ascorbic acid as capping agents.\u0000\u0000\u0000\u0000Synthesis of magnetite by two wet chemical methods namely: coprecipitation and solvothermal methods. The samples were characterized using X-ray diffraction (XRD), transmission electron microscope (TEM), and vibrating sample magnetometer (VSM).\u0000\u0000\u0000\u0000The results reveal the impact of coating on the size and morphology of the particles. The study also proves that autoclaving the samples prepared by coprecipitation results in smaller particle size and narrower size distribution due to digestive ripening. In addition, a novel and facile methodology for coating magnetite with polyethylene glycol is presented. The potential of the particles to be used for magnetic fluid hyperthermia is assessed by measuring the specific absorption rate (SAR) of the samples.\u0000\u0000\u0000\u0000The results show that all the prepared magnetite samples showed a promising capacity to be used as magnetic fluid hyperthermia agents.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47332860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-06DOI: 10.2174/2405461508666230606123103
Asmaa A. Mahdi, T. Salaheldin, M. Hendawey, Nahla S Hassan
This study aimed to examine the effect of magnetite coating of salicylic acid and Cu metal nanoparticles on yield, cellular contents, and some biochemical constituents of wheat subjected to heat stress. An applied experiment was conducted over two seasons at the Agricultural Experimental Station of Desert Research Center (DRC), which was supervised by the El Wadi El Gadeed Governorate in Egypt. The grains of wheat cultivars Sids1 (tolerant) and Gimmeza7 (sensitive) were treated with copper metal as NPs (Cu NPs) (0.25, 0.50, 0.75, 1.0, and 10ppm) and magnetite NPs (0.25, 0.50, 0.75, 1.0 and 10ppm) coated with salicylic acid at 100ppm (Fe NPs+SA). The objective of this study was to examine wheat tolerance to heat stress and subsequently yield by comparing two wheat cultivars under the same conditions. The chemically formulated nanoparticles were well characterized and applied in two wheat cultivars subjected to heat stress. The results showed that all NPs treatments had a positive impact on all physiological parameters and grain yield. Sids1 surpassed Gemmeiza7 in the quality of wheat grains (essential, non-essential amino acids). However, Gimmeza7 exceeded Sids1 in yield quantity, especially with the application of SA+Fe NPs at 0.50 ppm. These effects were associated with heat tolerance and the best survival in wheat cultivars. There was an increase in glutathione content, antioxidant enzymes (Glutathione -S- Transferase), and/or a decline in malondialdehyde content. Conclusion: Fe NPs+SA (0.5ppm) helped the Gimmeza7 cultivar to mitigate the effects of heat stress through activating growth, glutathione, and glutathione S transferase, enhancing yield quantity in two wheat cultivars (Misr1 and Gimmeza11), and decreasing their MDA content.
本研究旨在研究水杨酸和铜金属纳米颗粒的磁铁矿涂层对热胁迫下小麦产量、细胞含量和一些生化成分的影响。在埃及El Wadi El Gadeed省的监督下，在沙漠研究中心（DRC）的农业实验站进行了为期两个季节的应用实验。用金属铜NPs（0.25、0.50、0.75、1.0和10ppm）和水杨酸100ppm（Fe NPs+SA）处理小麦品种Sids1（耐）和Gimmeza7（敏感）的籽粒条件化学配制的纳米颗粒得到了很好的表征，并应用于两个遭受热胁迫的小麦品种。结果表明，所有NPs处理对所有生理参数和籽粒产量都有积极影响。Sids1在小麦籽粒质量（必需氨基酸和非必需氨基酸）方面超过了Gemmeiza7。然而，Gimmeza7在产量上超过了Sids1，特别是在施用0.50ppm的SA+Fe NP的情况下。这些效应与小麦品种的耐热性和最佳存活率有关。谷胱甘肽含量、抗氧化酶（谷胱甘肽-S-转移酶）增加，和/或丙二醛含量下降。结论：Fe-NPs+SA（0.5ppm）通过激活生长、谷胱甘肽和谷胱甘肽S转移酶，提高两个小麦品种（Misr1和Gimmeza11）的产量，降低MDA含量，有助于Gimmeza7减轻热胁迫的影响。
{"title":"The copper metal and magnetite nanoparticles conjugated with salicylic acid composite stimulated wheat defense mechanism and affected cellular components under heat stress","authors":"Asmaa A. Mahdi, T. Salaheldin, M. Hendawey, Nahla S Hassan","doi":"10.2174/2405461508666230606123103","DOIUrl":"https://doi.org/10.2174/2405461508666230606123103","url":null,"abstract":"\u0000\u0000This study aimed to examine the effect of magnetite coating of salicylic acid and Cu metal nanoparticles on yield, cellular contents, and some biochemical constituents of wheat subjected to heat stress.\u0000\u0000\u0000\u0000An applied experiment was conducted over two seasons at the Agricultural Experimental Station of Desert Research Center (DRC), which was supervised by the El Wadi El Gadeed Governorate in Egypt. The grains of wheat cultivars Sids1 (tolerant) and Gimmeza7 (sensitive) were treated with copper metal as NPs (Cu NPs) (0.25, 0.50, 0.75, 1.0, and 10ppm) and magnetite NPs (0.25, 0.50, 0.75, 1.0 and 10ppm) coated with salicylic acid at 100ppm (Fe NPs+SA).\u0000\u0000\u0000\u0000The objective of this study was to examine wheat tolerance to heat stress and subsequently yield by comparing two wheat cultivars under the same conditions.\u0000\u0000\u0000\u0000The chemically formulated nanoparticles were well characterized and applied in two wheat cultivars subjected to heat stress.\u0000\u0000\u0000\u0000The results showed that all NPs treatments had a positive impact on all physiological parameters and grain yield. Sids1 surpassed Gemmeiza7 in the quality of wheat grains (essential, non-essential amino acids). However, Gimmeza7 exceeded Sids1 in yield quantity, especially with the application of SA+Fe NPs at 0.50 ppm. These effects were associated with heat tolerance and the best survival in wheat cultivars. There was an increase in glutathione content, antioxidant enzymes (Glutathione -S- Transferase), and/or a decline in malondialdehyde content.\u0000\u0000\u0000\u0000Conclusion: Fe NPs+SA (0.5ppm) helped the Gimmeza7 cultivar to mitigate the effects of heat stress through activating growth, glutathione, and glutathione S transferase, enhancing yield quantity in two wheat cultivars (Misr1 and Gimmeza11), and decreasing their MDA content.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41795201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.2174/2405461508666230525124138
F. G. de Souza, Jonas Farias Santos, Leydi del R. Silva-Calpa, Krishnendu Pal
Nanotechnology is a cornerstone of the scientific advances witnessed over the past few years. Nanotechnology applications are extensively broad, and an overview of the main trends worldwide can give an insight into the most researched areas and gaps to be covered. This document presents an overview of the trend topics of the three leading countries studying in this area, as well as Brazil for comparison. The data mining was made from the Scopus database and analyzed using the VOSviewer and Voyant Tools software. More than 44.000 indexed articles published from 2010 to 2020 revealed that the countries responsible for the highest number of published articles are The United States, China, and India, while Brazil is in the fifteenth position. Thematic global networks revealed that the standing-out research topics are health science, energy, wastewater treatment, and electronics. In a temporal observation, the primary topics of research are: India (2020), which was devoted to facing SARS-COV 2; Brazil (2019), which is developing promising strategies to combat cancer; China (2018), whit research on nanomedicine and triboelectric nanogenerators; the United States (2017) and the Global tendencies (2018) are also related to the development of triboelectric nanogenerators. The collected data are available on GitHub. This study demonstrates the innovative use of data-mining technologies to gain a comprehensive understanding of nanotechnology's contributions and trends and highlights the diverse priorities of nations in this cutting-edge field.
{"title":"Central Countries' And Brazil's Contributions To Nanotechnology","authors":"F. G. de Souza, Jonas Farias Santos, Leydi del R. Silva-Calpa, Krishnendu Pal","doi":"10.2174/2405461508666230525124138","DOIUrl":"https://doi.org/10.2174/2405461508666230525124138","url":null,"abstract":"\u0000\u0000Nanotechnology is a cornerstone of the scientific advances witnessed over the past few years. Nanotechnology applications are extensively broad, and an overview of the main trends worldwide can give an insight into the most researched areas and gaps to be covered.\u0000\u0000\u0000\u0000This document presents an overview of the trend topics of the three leading countries studying in this area, as well as Brazil for comparison.\u0000\u0000\u0000\u0000The data mining was made from the Scopus database and analyzed using the VOSviewer and Voyant Tools software.\u0000\u0000\u0000\u0000More than 44.000 indexed articles published from 2010 to 2020 revealed that the countries responsible for the highest number of published articles are The United States, China, and India, while Brazil is in the fifteenth position. Thematic global networks revealed that the standing-out research topics are health science, energy, wastewater treatment, and electronics. In a temporal observation, the primary topics of research are: India (2020), which was devoted to facing SARS-COV 2; Brazil (2019), which is developing promising strategies to combat cancer; China (2018), whit research on nanomedicine and triboelectric nanogenerators; the United States (2017) and the Global tendencies (2018) are also related to the development of triboelectric nanogenerators. The collected data are available on GitHub.\u0000\u0000\u0000\u0000This study demonstrates the innovative use of data-mining technologies to gain a comprehensive understanding of nanotechnology's contributions and trends and highlights the diverse priorities of nations in this cutting-edge field.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42778590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-16DOI: 10.2174/2405461508666230502161945
K. Kayed, G. Mansour, Esaaf Alsoki
The utilization of nanoparticles (NPs) as an alternative to conventional methods to protect surfaces from bacteria is becoming increasingly popular. Nanotechnology has shown promise in providing long-lasting protection. This study focused on synthesizing Cu/CuxO composites on copper surfaces through thermal oxidation at varying temperatures. Optical reflectivity spectra of the composites were measured, and the plasma edges were observed in the range of 526-600 nm. To test the antibacterial properties of the composites, inhibition zone tests were conducted for Staphylococcus aureus. Results showed that the largest zone of inhibition was found in the sample treated at 100ο C. Furthermore, it was discovered that thermal oxidation decreased the ability of copper nanoparticles to inhibit bacteria.
{"title":"The Antimicrobial Activity of Cu/CuxO Composites Synthesized by\u0000Thermal Oxidation of Copper Tablets","authors":"K. Kayed, G. Mansour, Esaaf Alsoki","doi":"10.2174/2405461508666230502161945","DOIUrl":"https://doi.org/10.2174/2405461508666230502161945","url":null,"abstract":"\u0000\u0000The utilization of nanoparticles (NPs) as an alternative to conventional methods to protect\u0000surfaces from bacteria is becoming increasingly popular. Nanotechnology has shown promise in\u0000providing long-lasting protection. This study focused on synthesizing Cu/CuxO composites on copper\u0000surfaces through thermal oxidation at varying temperatures. Optical reflectivity spectra of the composites were measured, and the plasma edges were observed in the range of 526-600 nm. To test the antibacterial properties of the composites, inhibition zone tests were conducted for Staphylococcus aureus.\u0000Results showed that the largest zone of inhibition was found in the sample treated at 100ο\u0000C. Furthermore, it was discovered that thermal oxidation decreased the ability of copper nanoparticles to inhibit\u0000bacteria.\u0000","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42461073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-12DOI: 10.2174/2405461508666230512160837
Özgür Arar
Background: Because of its numerous advantages, biochar has been widely used to remove contaminants from aqueous media for several years. However, unmodified biochar often exhibits low sorption capacity. Therefore, various nano-sized metal oxides have been developed to modify biochar and improve its ability to remove impurities. Objective: This review aims to provide information on preparing and applying biochar loaded with nano-sized metal oxides to treat pollutants in water samples. Results: Raw biochar has limited applicability/capacity for certain pollutants, such as inorganic anions. However, modification with metal oxides improved removal performance, sorption capacity, and selectivity Conclusion: Biochar loaded with metal oxides is believed to be an environmentally friendly alternative for treating polluted water. Selective sorbents with high capacity and fast kinetics towards undesirable solutes can be produced using suitable metal oxides. The sorbent can remove pollutants from solutions with a high removal rate.
{"title":"Preparation of Nano-Metal-Oxide Incorporated Biochar for Remediation of Water Pollution","authors":"Özgür Arar","doi":"10.2174/2405461508666230512160837","DOIUrl":"https://doi.org/10.2174/2405461508666230512160837","url":null,"abstract":"Background: Because of its numerous advantages, biochar has been widely used to remove contaminants from aqueous media for several years. However, unmodified biochar often exhibits low sorption capacity. Therefore, various nano-sized metal oxides have been developed to modify biochar and improve its ability to remove impurities. Objective: This review aims to provide information on preparing and applying biochar loaded with nano-sized metal oxides to treat pollutants in water samples. Results: Raw biochar has limited applicability/capacity for certain pollutants, such as inorganic anions. However, modification with metal oxides improved removal performance, sorption capacity, and selectivity Conclusion: Biochar loaded with metal oxides is believed to be an environmentally friendly alternative for treating polluted water. Selective sorbents with high capacity and fast kinetics towards undesirable solutes can be produced using suitable metal oxides. The sorbent can remove pollutants from solutions with a high removal rate.","PeriodicalId":10924,"journal":{"name":"Current Nanomaterials","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135337236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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