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Efficient Fluoride removal from aqueous solution using Graphene/Ce composite supported on activated carbon 活性炭负载石墨烯/Ce复合材料高效去除水溶液中的氟化物
Q3 Materials Science Pub Date : 2023-01-10 DOI: 10.2174/2405461508666230110164054
R. Patel, C. P. Bhasin
More than 260 million people worldwide are affected by excess fluoride (F- > 1.5 mg/L) in their drinking water. Fluorosis of the teeth and skeleton, among other health issues, is caused by it.The aim of this study is to evaluate the fluoride removal from contaminated water using graphene-based new adsorbent material.Graphene (G) was prepared by a facile liquid-phase exfoliation method. CeO2 nanoparticles (NPs) were synthesized by the co-precipitation method. G was treated with CeO2 NPs in a probe sonicator to generate G/Ce material in solution. Finally, the impregnation evaporation process synthesized the G/Ce supported on activated carbon composite (G/Ce/AC).FE-SEM analysis shows that the crumpling and scrolling sheets of G, the nanosized spherical shape of CeO2 NPs and a thick layer of nano-sized spherical particles has built up on the surface of graphene in G/Ce/AC composite. After conversion to G/Ce/AC Composite, the specific surface area of graphene was increased from 3.08 to 485.3621 m2/g. The adsorption of fluoride on G/Ce/AC was investigated using batch systems (effects of pH, contact time, adsorbent dosage and the initial fluoride concentration), adsorption isotherm and kinetic studies. The pseudo-second order was the one that best described the kinetic data, while the Langmuir isotherm best described the equilibrium data with a maximum adsorption capacity equal to 27.9 mg/g.Therefore, the results show that the G/Ce/AC composite was well synthesized and has excellent fluoride adsorption capacity compared to other materials already evaluated for this purpose.
全世界有超过2.6亿人受到饮用水中过量氟化物(F->1.5 mg/L)的影响。除其他健康问题外,牙齿和骨骼的氟中毒也是由其引起的。本研究的目的是评估使用石墨烯基新型吸附材料从污染水中去除氟的效果。采用液相剥离法制备了石墨烯(G)。采用共沉淀法合成了CeO2纳米粒子。在探针超声仪中用CeO2 NP处理G以在溶液中产生G/Ce材料。最后,采用浸渍蒸发法合成了活性炭负载G/Ce复合材料(G/Ce/AC)。FE-SEM分析表明,在G/Ce/AC复合材料中,石墨烯表面形成了G的褶皱和滚动片、CeO2纳米颗粒的纳米球形和一层厚厚的纳米球形颗粒。转化为G/Ce/AC复合材料后,石墨烯的比表面积从3.08增加到485.3621 m2/G。采用间歇体系(pH、接触时间、吸附剂用量和氟化物初始浓度的影响)、吸附等温线和动力学研究了G/Ce/AC对氟化物的吸附。伪二阶是最能描述动力学数据的一阶,而Langmuir等温线最能描述最大吸附量为27.9mg/g的平衡数据。因此,结果表明,与已经为此目的评估的其他材料相比,G/Ce/AC复合材料合成良好,并且具有优异的氟化物吸附能力。
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引用次数: 0
ZnO nanostructure based Gas Sensors: Critical review based on their synthesis and morphology towards various oxidizing and reducing gases 基于ZnO纳米结构的气体传感器:基于各种氧化还原性气体的合成和形貌的综述
Q3 Materials Science Pub Date : 2022-12-29 DOI: 10.2174/2405461508666221229103713
Shilpa Jain, T. Shaikh
Nanotechnology has enabled sensors to detect and sense a very small amount of chemical vapors. Sensors play a major role in our daily life. The use of sensors has made human life easy. One such type of sensor is the Gas sensor made up of Semiconducting metal oxides. These sensors have their own unique features which help in the easy monitoring of toxic gases. Out of all the metal oxide present, the gas sensors made up of ZnO nanostructures are mostly used in the gas sensing industry. ZnO has become a research hotspot of gas-sensing material because of the variation in resistance observed on the surface. These resistance changes are observed due to the adsorption & desorption of gases. In this review, we will be discussing the ZnO nanostructures, their preparation and their applications in the sensing of various toxic and flammable gases.
纳米技术使传感器能够检测和感应极少量的化学蒸汽。传感器在我们的日常生活中发挥着重要作用。传感器的使用使人类的生活变得简单。一种这样类型的传感器是由半导体金属氧化物制成的气体传感器。这些传感器有自己独特的功能,有助于轻松监测有毒气体。在所有存在的金属氧化物中,由ZnO纳米结构组成的气体传感器主要用于气体传感行业。ZnO由于其表面电阻的变化而成为气敏材料的研究热点。这些电阻变化是由于气体的吸附和解吸引起的。在这篇综述中,我们将讨论ZnO纳米结构、它们的制备及其在各种有毒和易燃气体传感中的应用。
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引用次数: 0
Nanomaterials: Potential Broad Spectrum Antimicrobial Agents 纳米材料:潜在的广谱抗菌剂
Q3 Materials Science Pub Date : 2022-12-14 DOI: 10.2174/2405461508666221214120304
Prabhurajeshwar Chidre, Ashajyothi Chavan, Navya Hulikunte Mallikarjunaiah, C. Kelmani
Nanotechnology is a promising science with new aspects to fight and prevent various diseases using nanomaterials. The capability to expose the structure and functions of biosystems at the nanoscale level supports research leading to development in biology, biotechnology, medicine and healthcare. This is predominantly advantageous in treating microbial infections as an alternative to antibiotics. However, widespread production, and use and misuse of antibiotics have led to the emergence of multiple-drug resistant (MDR) pathogenic bacteria. Due to infectious diseases from these drug-resistant pathogenic strains, human mortality rates have consistently increased and are becoming an epidemic in our society. Consequently, there is a strong demand for developing novel strategies and new materials that can cope with these problems. The emergence of nanotechnology has created many new antimicrobial options. The small size of these nanomaterials is suitable for carrying out biological operations. Several metals and metal oxides, such as silver, copper, gold, zinc oxide and iron oxide nanoparticle types, have shown toxicity toward several pathogenic microbes. Metal-based nanoparticles have been broadly examined for a set of biomedical applications. According to the World Health Organization, the reduced size and selectivity of metal-based nanoparticles for bacteria have established them to be effective against pathogens, causing concern. Metal-based nanoparticles are known to have non-specific bacterial toxicity mechanisms, which not only make the development of resistance by bacteria difficult, but also widen the spectrum of antibacterial activity. Metal-based nanoparticle efficiency studies achieved so far have revealed promising results against both Gram-positive and Gram-negative bacteria. Here we discuss the potential nanomaterials to either treat microbial resistance or induce the development of resistance. However, fundamental research is required to focus on the molecular mechanism causing the antimicrobial activity of nanomaterials.
纳米技术是一门很有前途的科学,具有利用纳米材料对抗和预防各种疾病的新方面。在纳米尺度上揭示生物系统结构和功能的能力支持了生物学、生物技术、医学和医疗保健领域的研究发展。这在作为抗生素的替代品治疗微生物感染方面是主要有利的。然而,抗生素的广泛生产、使用和滥用导致了多药耐药(MDR)病原菌的出现。由于这些耐药致病菌株的传染病,人类死亡率持续上升,并正在成为我们社会的流行病。因此,对开发能够应对这些问题的新策略和新材料有着强烈的需求。纳米技术的出现创造了许多新的抗菌选择。这些纳米材料体积小,适合进行生物操作。几种金属和金属氧化物,如银、铜、金、氧化锌和氧化铁纳米颗粒类型,已显示出对几种致病微生物的毒性。基于金属的纳米颗粒已被广泛用于一系列生物医学应用。根据世界卫生组织的说法,金属基纳米颗粒对细菌的尺寸和选择性降低,使其对病原体有效,这引起了人们的担忧。众所周知,金属基纳米颗粒具有非特异性的细菌毒性机制,这不仅使细菌难以产生耐药性,而且拓宽了抗菌活性的范围。到目前为止,基于金属的纳米颗粒效率研究已经揭示了对抗革兰氏阳性菌和革兰氏阴性菌的有希望的结果。在这里,我们讨论了处理微生物耐药性或诱导耐药性发展的潜在纳米材料。然而,基础研究需要集中在引起纳米材料抗菌活性的分子机制上。
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引用次数: 4
Fabrication of zein/PVA fibre blends: Optimizing concentration and applied voltage 玉米醇溶蛋白/PVA纤维共混物的制备:优化浓度和施加电压
Q3 Materials Science Pub Date : 2022-12-05 DOI: 10.2174/2405461508666221205091152
M. Moloto, Nompumelelo S. M. Kubheka, Nolutho Mkhumbeni
The fabrication of polymer fibre blends has gained much attention for the development of innovative nanomaterials. Polymer fibre blends are nanomaterials with different functionalities and properties such as a sizeable surface-to-area ratio, high porosity, flexibility, and stability. The focus of this study was to produce zein/PVA fibre blends using the electrospinning technique and varying parameters such as concentration and applied voltage. The two parameters are key driving factors for the production of fibres. Zein as a natural polymer has challenges in developing fibre materials which require artificial polymers like PVA to create a good blending mixture for electrospinning.The zein/PVA nanofibre blends were fabricated using the electrospinning technique. The FE-SEM (Leo, Zeiss) was used to study the surface morphologies of the zein/PVA nanofibers blends. The optical properties of the nanofibre blends were determined using the UV-vis spectrophotometer and the chemical structure and composition of zein/PVA nanofibers blends were studied using Thermo Scientific Nicolet iS50-FTIR spectrometer, universal ATR with the diamond detector.The SEM images showed smooth zein/PVA ribbon-like nanofibre blends of 90/10, 80/20, 70/30, 60/40, and 50/50. SEM images of zein/PVA (80/20) electrospun at 25 kV were obtained to be the maximum fibre yield due to zein/PVA compatibility, increased conductivity, and enhanced fibre formation. The optical properties (absorption spectroscopy) suggested that the zein/PVA (80/20) fibre blend was miscible, and the FTIR spectra confirmed their functional groups. Therefore, the characterization results showed that the polymer blended solutions concentration and applied voltage increment affected fibre size distribution and morphology.Optimizing concentration and applied voltage successfully produced smooth, uniform bead-free zein/PVA fibre blends as parameters are increased.
聚合物纤维共混物的制备因创新纳米材料的开发而备受关注。聚合物纤维混合物是具有不同功能和性能的纳米材料,如相当大的表面积比、高孔隙率、柔韧性和稳定性。本研究的重点是使用静电纺丝技术和不同的参数(如浓度和施加电压)生产玉米醇溶蛋白/PVA纤维混合物。这两个参数是纤维生产的关键驱动因素。Zein作为一种天然聚合物,在开发纤维材料方面面临挑战,因为纤维材料需要PVA等人造聚合物来制造用于静电纺丝的良好混合混合物。采用静电纺丝技术制备了玉米醇溶蛋白/PVA纳米纤维共混物。采用FE-SEM(Leo,Zeiss)研究了玉米醇溶蛋白/PVA纳米纤维共混物的表面形貌。用紫外-可见分光光度计测定了纳米纤维共混物的光学性能,并用Thermo Scientific Nicolet iS50 FTIR光谱仪、带金刚石检测器的通用ATR研究了玉米醇溶蛋白/PVA纳米纤维共混体的化学结构和组成。SEM图像显示90/10、80/20、70/30、60/40和50/50的光滑玉米醇溶蛋白/PVA带状纳米纤维共混物。由于玉米醇溶蛋白/PVA的相容性、增加的导电性和增强的纤维形成,获得了在25kV下电纺的玉米醇溶素/PVA(80/20)的SEM图像,这是最大的纤维产率。光学性质(吸收光谱)表明玉米醇溶蛋白/PVA(80/20)纤维共混物是可混溶的,FTIR光谱证实了它们的官能团。因此,表征结果表明,聚合物共混溶液的浓度和施加的电压增量影响纤维的尺寸分布和形态。随着参数的增加,优化浓度和施加电压成功地制备了光滑、均匀的无珠玉米醇溶蛋白/PVA纤维共混物。
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引用次数: 0
Meet the Editorial Board Member 与编辑委员会成员见面
Q3 Materials Science Pub Date : 2022-12-01 DOI: 10.2174/240546150703220831113414
S. Harikrishnan
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引用次数: 0
Structure, Composition, and Morphology of self-Assembled 2D Nanostructures Based on SnO2 Nanoparticles Observed in Unannealed Mn Doped Hydrated Form of Tin Oxide (II) or (IV) Synthesized by Co-precipitation Method 基于SnO2纳米粒子的自组装2D纳米结构的结构、组成和形态,在通过共沉淀法合成的未退火的掺Mn水合形式的氧化锡(II)或(IV)中观察到
Q3 Materials Science Pub Date : 2022-11-28 DOI: 10.2174/2405461508666221128111706
D. García-Gutiérrez, J. E. Reyes-González, D. F. Garcia-Gutierrez, M. A. Garza-Navarro
2D nanostructures are greatly interested in different technological applications, particularly optoelectronics. Tin oxide 2D nanostructures have shown great transparency and ideal charge carrier transport properties.The current study aims to evaluate the main characteristics of 2D-nanostructures observed during the synthesis of hydrated forms of tin oxide (II) or (IV) doped with Mn.A chemical co-precipitation method was used for the synthesis of the hydrated forms of tin oxide (II) or (IV) with different conditions on time (1 and 1.5 h) and temperature (60ºC and 90ºC), using MnCl2 as the manganese source.X-ray diffraction and XPS results revealed the formation of the hydroromarchite phase (Sn6O4(OH)4) as the main product of the synthesis reaction. Scanning electron microscopy images were used to identify and measure, in a first approach, the 2D nanostructures observed as a result of the synthesis. Morphological characterization using different transmission electron microscopy techniques revealed the presence of nanoparticles that were observed to self-assemble to form the 2D nanostructures observed (nanorods and nanosheets). Nonetheless, selected-area electron diffraction suggested the presence of the cassiterite phase (SnO2) in the nanoparticles forming the 2D nanostructures. Furthermore, chemical analyses using energy-dispersive X-ray spectroscopy supported the observations made by the diffraction studies regarding the presence of cassiterite phase (SnO2) in the 2D nanostructures. The number of 2D nanostructures observed in the analyzed samples increased as the Mn concentration increased in the synthesis reaction.The addition of Mn as an intended doping element increased the crystallite size and the polycrystallinity of the synthesized hydrated forms of tin oxide (II) or (IV). Additionally, it also promoted the formation of 2D nanostructures made of SnO2 nanoparticles.
2D纳米结构对不同的技术应用非常感兴趣,尤其是光电子。氧化锡2D纳米结构显示出良好的透明度和理想的电荷载流子传输特性。目前的研究旨在评估在合成水合形式的氧化锡(II)或掺有Mn的(IV)过程中观察到的2D纳米结构的主要特征。使用化学共沉淀法在不同的时间(1和1.5小时)和温度(60ºC和90ºC)条件下合成水合形式氧化锡(Ⅱ)或(IV),使用MnCl2作为锰源。X射线衍射和XPS结果显示形成了作为合成反应的主要产物的水铝石相(Sn6O4(OH)4)。在第一种方法中,使用扫描电子显微镜图像来识别和测量作为合成结果观察到的2D纳米结构。使用不同透射电子显微镜技术的形态表征揭示了纳米颗粒的存在,这些纳米颗粒被观察到自组装以形成所观察到的2D纳米结构(纳米棒和纳米片)。尽管如此,选区电子衍射表明在形成2D纳米结构的纳米颗粒中存在锡石相(SnO2)。此外,使用能量色散X射线光谱的化学分析支持了衍射研究对2D纳米结构中锡石相(SnO2)存在的观察结果。在分析的样品中观察到的2D纳米结构的数量随着合成反应中Mn浓度的增加而增加。添加Mn作为预期的掺杂元素增加了合成的水合形式的氧化锡(II)或(IV)的微晶尺寸和多晶性。此外,它还促进了由SnO2纳米颗粒制成的2D纳米结构的形成。
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引用次数: 0
Adsorption of Chromium (VI) from Aqueous Solution Using Nano TiO2 Doped Strong Base Anion Exchange Resin 纳米TiO2掺杂强碱阴离子交换树脂对水溶液中铬(VI)的吸附研究
Q3 Materials Science Pub Date : 2022-11-24 DOI: 10.2174/2405461508666221124161113
R. Kulkarni, P. Koujalagi, Harish N. Revankar, Vijayendra R Gurjar
The evolution of environmentally-safe methods for treating hazardous chemicals in wastewater, particularly urban and industrial wastewater, has increased interest over recent years. The chromium-containing wastewater is produced by industries from steel, metallurgical, electroplating, chemical, refractory, leather tanning, dye manufacturing, mining, cementing, textiles, etc. Consequently, advanced techniques are essential for treating chromium-polluted water.The prime objective of this effort was to assess the adsorption performance of nanoTiO2 (nanoparticles of average crystallite size 19.15 nm) doped strong base anion exchange resin (TD-Tulsion) for Cr(VI)to that of the host Tulsion A-62 (MP).The tests were carried out in batches in the temperature-controlled water bath shaking unit, with 30 ml of the aqueous solution containing Cr(VI) and a certain amount of resin being stirred for 6 hours at 303 K. Using a standard diphenylcarbazide (DPC) procedure at 540 nm, the solution was spectrophotometrically analyzed for Cr(VI).The majority of the Cr(VI) ions are adsorbed by the anion exchange resins Tulsion A-62(MP), and TD-Tulsion is in the pH range of 4.0 to 5.0. The maximal sorption capacity of Cr (VI) was established to be 181.5 and 204.8 mg/g for Tulsion A-62(MP) and TD-Tulsion, respectively.The TD-Tulsion has a substantially better adsorption capacity than Tulsion A-62(MP) under similar conditions. The outcomes show that modifying anion-exchange resin with nano titanium dioxide improves adsorption performance in Cr(VI) removal from drinking water and contaminated water.
近年来,人们对处理废水,特别是城市和工业废水中危险化学品的环境安全方法的发展越来越感兴趣。含铬废水来源于钢铁、冶金、电镀、化工、耐火材料、皮革制革、染料制造、采矿、水泥、纺织等行业。因此,先进的技术是处理铬污染水的必要条件。这项工作的主要目的是评估掺杂纳米TiO2(平均晶粒尺寸19.15nm的纳米颗粒)的强碱阴离子交换树脂(TD Tulsion)对Cr(VI)的吸附性能与宿主Tulsion A-62(MP)的吸附能力,将含有Cr(VI)的30ml水溶液和一定量的树脂在303K下搅拌6小时。使用标准二苯基碳酰肼(DPC)程序在540nm下对溶液进行Cr(Ⅵ)的分光光度分析。大多数Cr(VI)离子被阴离子交换树脂Tulsion a-62(MP)吸附,TD Tulsion的pH范围为4.0至5.0。Tulsion A-62(MP)和TD Tulsion对Cr(VI)的最大吸附能力分别为181.5和204.8 mg/g。在类似条件下,TD Tulsion比Tulsion a-62(MP)具有更好的吸附能力。结果表明,用纳米二氧化钛改性阴离子交换树脂可以提高饮用水和污水中Cr(VI)的吸附性能。
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引用次数: 0
Nanotechnology In Smart Contact Lenses: Highlights On Sensor Technologies And Future Prospects 智能隐形眼镜中的纳米技术:传感器技术的亮点和未来展望
Q3 Materials Science Pub Date : 2022-11-18 DOI: 10.2174/2405461508666221118153823
J. R
The eye is a complex organ in the body containing a repertoire of metabolite indicators such as glucose, peptides, specialized ions, and many critical biological data such as intraocular pressure (IOP), corneal temperature, and pH. Contact lens research and patient care have progressed substantially throughout the last three decades; hence smart contact lenses were developed with significant advancements in material biocompatibility, better lens layouts, the healthcare system, and more flexible and efficient modalities. Smart contact lenses are adjustable sophisticated visual prosthesis devices that monitor various significant physical and biochemical changes in ocular disorders, which are noninvasive and continuous. Wearable systems that utilize bodily fluids like sweat tears, saliva, and electrochemical interactions with steady physiological state and illness monitoring are currently developing. Because of its ease of access, fabrication, and noninvasiveness, tear fluid is commonly used to assess ocular disorders, blood glucose, and even cancers. Furthermore, the integration of nanotechnology into contact lenses has emerged as a promising platform for noninvasive point-of-care diagnostics. Utilizing nano-based contact lenses for ocular drug delivery is a new study area in bioengineering and innovative medical techniques. Despite all of the research done in this area, new technologies are still in their early stages of development, and more work in terms of clinical trials is required to commercialize nanotechnology-based contact lenses. This article encompasses nanotechnology-based smart contact lens technology, including materials, advancements, applications, sensor technologies, and prospects.
眼睛是人体中一个复杂的器官,包含一系列代谢物指标,如葡萄糖、多肽、特殊离子和许多关键的生物学数据,如眼压(IOP)、角膜温度和ph。在过去的三十年中,隐形眼镜的研究和患者护理取得了实质性进展;因此,智能隐形眼镜的开发在材料生物相容性、更好的镜片布局、医疗保健系统和更灵活有效的模式方面取得了重大进展。智能隐形眼镜是一种可调节的精密视觉假体设备,用于监测眼部疾病中各种显著的物理和生化变化,具有非侵入性和连续性。目前正在开发利用体液(如汗液、唾液)和电化学相互作用来稳定生理状态和疾病监测的可穿戴系统。由于泪液易于获取、制作和非侵入性,通常用于评估眼部疾病、血糖甚至癌症。此外,将纳米技术集成到隐形眼镜中已经成为一种有前途的无创即时诊断平台。利用纳米隐形眼镜进行眼部给药是生物工程和创新医学技术的一个新的研究领域。尽管在这一领域进行了所有的研究,但新技术仍处于发展的早期阶段,要使基于纳米技术的隐形眼镜商业化,还需要进行更多的临床试验。本文介绍了基于纳米技术的智能隐形眼镜技术,包括材料、进展、应用、传感器技术和前景。
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引用次数: 2
Agro-waste Mediated Biosynthesis of Zinc Oxide Nanoparticles and their Antibacterial Properties: Waste to Treat 农业废弃物介导的氧化锌纳米粒子的生物合成及其抗菌性能:待处理废弃物
Q3 Materials Science Pub Date : 2022-11-18 DOI: 10.2174/2405461508666221118155210
Laxman Singh, D. Singh, D. Rawat, Amar Kumar, Preeti Rawat, R. Singhal
Biogenic fabrication of metal oxide nanoparticles has been gaining interest over conventional methods. Biological methods make use of plant materials and microbial agents as reducing as well as capping agents. The present work reports the biosynthesis of ZnO NPs from agricultural wastes produced in every household.A significant portion of municipal solid organic waste (MSOW) consists of agricultural waste. Utilization of this agricultural waste towards cleaning water of pathogens through the synthesis of nanoparticles has far-reaching implications, such as curbing soil pollution and water pollution.Preliminary confirmation was done by the visual formation of a pale yellow/dirty white precipitate of ZnO NPs. These were further characterized by different spectroscopic techniques, such as FT-IR, SEM, EDAX, and HRTEM.The HRTEM study revealed that NPs obtained had sizes between 30-52 nm. Fabricated ZnO NPs were analyzed for their antibacterial activity by disk diffusion method, and they exhibited striking antibacterial activity against E. coli and bacillus subtilis.Exploring the potential of waste and its conversion into a value-added product is a novel step. ZnO nanoparticles were successfully synthesized from agricultural wastes through an environmentally friendly synthetic route, and the synthesized ZnO NPs were found to be potent in inhibiting the growth of bacteria.
生物制备金属氧化物纳米颗粒的研究已经超过了传统的方法。生物方法利用植物材料和微生物剂作为还原剂和封盖剂。本文报道了从每个家庭产生的农业废弃物中生物合成氧化锌NPs的情况。城市固体有机废物(MSOW)中有很大一部分是农业废物。利用这种农业废弃物通过合成纳米颗粒来净化水中的病原体具有深远的意义,如抑制土壤污染和水污染。氧化锌纳米粒子的淡黄色/脏白色沉淀物的视觉形成初步证实了这一点。通过不同的光谱技术,如FT-IR, SEM, EDAX和HRTEM进一步表征。HRTEM研究表明,所获得的NPs的尺寸在30-52 nm之间。采用圆盘扩散法对制备的ZnO NPs进行了抑菌活性分析,结果表明ZnO NPs对大肠杆菌和枯草芽孢杆菌具有明显的抑菌活性。探索废物的潜力并将其转化为增值产品是一个新颖的步骤。通过环境友好的合成途径,成功地从农业废弃物中合成了氧化锌纳米粒子,并发现合成的氧化锌纳米粒子具有抑制细菌生长的有效作用。
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引用次数: 0
A Comprehensive Review of Nanoemulsion applications & their recent advancements 纳米乳液的应用及其最新进展
Q3 Materials Science Pub Date : 2022-11-03 DOI: 10.2174/2405461508666221103121439
Prativa Das, Jnyana Ranjan Panda, C. Patro, Baby Sahu, Soumya Stuti Patnaik
Nanoemulsions are submicron-sized suspensions that are being studied extensively as pharmacological vehicles for enhancing the outcomes of drug delivery. Nanoemulsions are isotropic thermodynamic systems in which two immiscible liquids [water and oil] are combined to form a single phase using pertinent surfactants. Nano-emulsions are resilient to sedimentation or creaming due to their nano-droplet size. Ostwald ripening represents the principal process accountable for the disintegration of nanoemulsion. Droplet diameters in nanoemulsions typically range from 20 to 500 nanometers. The diameter and surface parameters of nanoemulsion droplets play are of paramount significance in determining the bioactivity of the formulation. Nanoemulsion offers a promising future in various industries like cosmetology, diagnosis, pharmacological regimens, and biomedicine in the future.Pharmaceutical surfactants are utilized to synthesize nanoemulsions, which are generally regarded as safe [GRAS]. The stability of the NEs against coalescence mainly depends on the type and concentration of the surfactant employed. Nanoemulsions are formulated from a variety of oils, notably natural, semi-synthetic, and synthetic oils.Over the past decade, various patents and clinical research have exemplified the applications of the NE system. Their application as a drug delivery entity in the ophthalmic, topical, transdermal, intranasal, intravenous, and oral routes is widely appreciated. Also, they have gained remarkable importance in the cosmetic industry.This review presents the importance of various components of NE and their importance in droplet formation and provides a brief insight into various drug administration routes of NE.
纳米乳剂是一种亚微米大小的悬浮液,作为增强药物传递效果的药理学载体被广泛研究。纳米乳液是各向同性的热力学系统,其中两种不混溶的液体(水和油)使用相关的表面活性剂结合形成单相。纳米乳剂由于其纳米液滴大小而具有抗沉降或成乳的弹性。奥斯特瓦尔德成熟是纳米乳分解的主要过程。纳米乳剂中的液滴直径通常在20到500纳米之间。纳米乳液滴的直径和表面参数是决定制剂生物活性的重要因素。纳米乳液在美容、诊断、药物治疗、生物医学等领域有着广阔的应用前景。药物表面活性剂被用于合成纳米乳液,通常被认为是安全的[GRAS]。NEs抗聚结的稳定性主要取决于所使用的表面活性剂的类型和浓度。纳米乳液由多种油配制而成,尤其是天然油、半合成油和合成油。在过去的十年中,各种专利和临床研究都证明了NE系统的应用。它们作为药物递送实体在眼科、外用、透皮、鼻内、静脉和口服途径中的应用受到广泛赞赏。此外,它们在化妆品行业也获得了显著的重要性。本文综述了NE的各种成分及其在微滴形成中的重要性,并简要介绍了NE的各种给药途径。
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Current Nanomaterials
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