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Computational Tool for Calculation of Tissue Air Ratio and Tissue Maximum Ratio in Radiation Dosimetry 辐射剂量学中组织空气比和组织最大比的计算工具
Pub Date : 2019-01-03 DOI: 10.19080/ctbeb.2019.17.555966
Atia Atiq
In radiation therapy, it is essential to calculate the dosimetric quantities such as Percentage Depth Dose (PDD), Tissue Air Ratio (TAR), and Tissue Maximum Ratio (TMR). The basic depth dose data was determined by dosimetric measurements taken in dummy patients (phantoms), which have density nearly equal to human body tissues, with ionization chamber placed in them [1]. A system for absorbed dose calculations has been developed to foresee the depth dose distribution in patients going to be treated. The radiation dose deposited by ionizing radiations within the patient or medium varies with the varying depth. This variation is due to different parameters like depth, beam energy, field size, Source to Surface Distance (SSD). While calculating absorbed doses, greater considerations must be given to these parameters as they cause changes to depth dose distributions [2]. Plenty of radiotherapy units, such as linac and cobalt-60 units, accomplish the treatment of cancerous parts. To treat cancerous tissues, cobalt 60 gamma ray beam is used for more than fifty years in radiotherapy [3].
在放射治疗中,必须计算剂量学量,如百分比深度剂量(PDD)、组织空气比(TAR)和组织最大比(TMR)。基本的深度剂量数据是通过在假病人(幻影)中进行的剂量学测量来确定的,假病人的密度几乎等于人体组织,并在其中放置电离室。一种计算吸收剂量的系统已被开发出来,以预测将要治疗的病人体内的深度剂量分布。电离辐射在病人或介质内沉积的辐射剂量随深度的变化而变化。这种变化是由于不同的参数,如深度,光束能量,场大小,源到表面距离(SSD)。在计算吸收剂量时,必须更多地考虑这些参数,因为它们会引起深度剂量分布的变化。许多放射治疗装置,如直线加速器和钴-60装置,可以完成癌变部位的治疗。为了治疗癌变组织,钴60伽马射线束在放射治疗中使用了50多年。
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引用次数: 2
Study on Stress among Male Resident Medical Students: A Cause of Concern 男住院医学生的压力研究:一个值得关注的问题
Pub Date : 2018-12-18 DOI: 10.19080/CTBEB.2019.17.555967
Mohammad Sarwar Mir
Introduction : Stress is an inevitable part of medical education and is especially common in Resident medical scholars. Objective: To study causes of stress among Resident medical students. Material and methods: A cross-sectional study was carried in May 2015. A 140 male resident scholars were included and gave consent. A predesigned, semi structured questionnaire was used. Result: Analysis shows that 71.4% of the respondents experienced stress. Being way from the family, large syllabus, and lack of time to revise were the major causes of stress among the students. Conclusion: A good proportion of resident medical students were found to be stressed, with academic stressors being the major cause of stress among the subjects.
压力是医学教育不可避免的一部分,在住院医师中尤为普遍。目的:探讨住院医学生压力产生的原因。材料与方法:于2015年5月进行横断面研究。调查对象为140名男性常驻学者,均表示同意。采用预先设计的半结构化问卷。结果:分析显示,71.4%的受访者经历过压力。远离家庭、大的教学大纲以及没有时间复习是学生们压力的主要原因。结论:住院医学生有一定比例的压力,学业压力源是造成住院医学生压力的主要原因。
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引用次数: 0
Detection of the Viral Infectious Diseases in Blood by Surface-Enhanced Raman Spectroscopy: Mini Review 表面增强拉曼光谱检测血液中病毒性传染病的研究进展
Pub Date : 2018-12-17 DOI: 10.19080/ctbeb.2018.17.555965
Y. Yeh
Raman spectroscopy is an optical spectroscopic technique that is commonly used to identify the vibrational modes of a substance. However, the efficiency of exciting Raman scattering is very weak—approximately 1 out of 106 phonons are absorbed and emitted through Raman scattering. This weak efficiency dramatically limits the signal intensity of Raman spectroscopy. Studies have shown that metal nanoparticles can dramatically enhance Raman scattering via a nanoparticles-based localized plasmon resonance (LSPR). This enhancement of the Raman signal enables detection down to the single molecule level (~picomolar) [1,2]. Surface-enhanced Raman spectroscopy (SERS) is a technique which induces local surface plasmons at the vicinity of a metal or dielectric material by laser excitation to enhance the Raman signal. This surface-based detection technique can enhance the Raman signal up to 1010 by molecular adsorption on a rough metal surface and makes single biomolecular detection possible if the target molecule is near the metal surface [3,4]. When detecting viruses there are two conventional approaches to bringing the target virus close to the rough metal, one is through antibody-conjugated nanoparticles, and the other is through surface engineered metal nanostructures. In the following, we will focus on reviewing SERS based detection for different infectious diseases.
拉曼光谱是一种光学光谱技术,通常用于识别物质的振动模式。然而,激发拉曼散射的效率非常低,大约每106个声子中有1个通过拉曼散射被吸收和发射。这种微弱的效率极大地限制了拉曼光谱的信号强度。研究表明,金属纳米粒子可以通过基于纳米粒子的局部等离子体共振(LSPR)显著增强拉曼散射。这种拉曼信号的增强使得检测可以降低到单分子水平(~皮摩尔)[1,2]。表面增强拉曼光谱(SERS)是一种利用激光激发在金属或介质材料附近诱导局部表面等离子体以增强拉曼信号的技术。这种基于表面的检测技术可以通过分子吸附在粗糙的金属表面上将拉曼信号增强到1010,并且如果目标分子靠近金属表面,则可以检测单个生物分子[3,4]。在检测病毒时,有两种常规方法使目标病毒接近粗金属,一种是通过抗体结合的纳米颗粒,另一种是通过表面工程金属纳米结构。下面,我们将重点综述基于SERS的不同传染病检测方法。
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引用次数: 0
Can Bacteriocins Curb the Emergence of Antibiotic Resistant Pathogenic Bacteria in the Globe? 细菌素能抑制全球抗生素耐药致病菌的出现吗?
Pub Date : 2018-12-17 DOI: 10.19080/ctbeb.2018.17.555964
S. Mandal
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引用次数: 1
Self‐Medication Patterns among Medical Students in North India 印度北部医科学生的自我用药模式
Pub Date : 2018-12-13 DOI: 10.19080/CTBEB.2019.17.555968
Mohammad Sarwar Mir
Introduction Self-medication results in wastage of resources, increases resistance of pathogens and generally causes serious health hazards such as adverse drug reactions, prolonged suffering and drug dependence.  Method A cross‐sectional descriptive study was conducted. The participants were medical students from first to final year. The data was collected using a questionnaire. The data was analyzed using SPSS version 2.0.  Results   A total of 100 students, 61 (61.00%) male and 39 (39.00%) female were included in the study. Of the medical students surveyed, self-medication was reported among 88%. The most common ailments for which self-medication were used were: the common cold and headache. The students consulted their textbooks and peers for the medications. Antipyretics and analgesics were the most common self‐ medicated drugs.  Conclusions the prevalence of self‐medication among medical students is high, facilitated by the easy availability of drugs and information from textbooks or seniors. The potential problems of self‐medication should be emphasized to the students.
自我药疗造成资源浪费,增加病原体的抵抗力,并通常造成严重的健康危害,如药物不良反应、长期痛苦和药物依赖。方法采用横断面描述性研究。参与者是一年级到最后一年级的医学院学生。数据是通过问卷调查收集的。采用SPSS 2.0对数据进行分析。结果共纳入100名学生,其中男性61人(61.00%),女性39人(39.00%)。在接受调查的医学生中,88%的人报告自我药疗。使用自我药物治疗的最常见疾病是:普通感冒和头痛。学生们查阅了课本和同龄人的用药情况。退烧药和镇痛药是最常见的自用药。结论医学生自我药疗的比例较高,这是由于药物容易获得以及从课本或学长那里获得的信息。应向学生强调自我用药的潜在问题。
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引用次数: 189
Role of Stem Cells in Treatment of Acanthamoebic Corneal Ulcer 干细胞在棘阿米巴性角膜溃疡治疗中的作用
Pub Date : 2018-12-11 DOI: 10.19080/ctbeb.2018.17.555963
Khadiga Ahmed Ismail
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引用次数: 1
Book Review ‘Dadah: Apa Anda Perlu Tahu’ (Malay Version)
Pub Date : 2018-12-10 DOI: 10.19080/ctbeb.2019.18.555996
U. Iqbal
Maintained by the Anti-Drug Task Force from the National Security Council, Prime Minister’s Department, this book is provided as a resource for identifying and understanding the drug problem in depth. It explains the aspects of the problem of drug problems, types and ways of detecting drugs, the effects and consequences of drug addiction, how to identify drug addicts, drug addiction problems, mistakes and penalties, how to get help and community involvement in drug prevention. The first chapter explains the problem of drug problems faced by the country, from the start of the drug being introduced to Malaysia to the widespread spread of drugs, from the use of opiates to heroin, from the old society to the young. Chapter Two introduces readers to various types of drugs and hazards including drug designer drugs derived from artificial chemicals, which are no less harmful than opiate drugs. Chapter Three affects drug use on addicts, consequences to self, society and nation. This chapter provides guidance on how to identify and identify individuals taking drugs. Chapter Four presents the steps taken by the Government to control drug problems. It covers Malaysia’s overall policy and strategy from prevention, recovery to international strategies. This chapter emphasizes that Government’s efforts alone will not be effective in combating drug problems. It requires total commitment from all parties.
这本书是由首相署国家安全委员会禁毒工作小组维护的,是一种深入识别和了解毒品问题的资源。它解释了毒品问题的各个方面,毒品的类型和检测毒品的方法,吸毒成瘾的影响和后果,如何识别吸毒成瘾者,吸毒成瘾问题,错误和惩罚,如何获得帮助和社区参与毒品预防。第一章解释了我国面临的毒品问题,从毒品被引入马来西亚的开始到毒品的广泛传播,从使用鸦片剂到海洛因,从旧社会到年轻人。第二章向读者介绍了各种类型的药物和危害,包括从人造化学品中提取的药物设计药物,其危害不亚于鸦片类药物。第三章吸毒对吸毒者的影响、对个人、社会和国家的后果。本章提供了如何识别和识别吸毒人员的指导。第四章介绍政府为管制毒品问题所采取的步骤。它涵盖了马来西亚从预防、恢复到国际战略的总体政策和战略。本章强调,仅靠政府的努力并不能有效地解决毒品问题。它需要各方作出全面承诺。
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引用次数: 1
Directing Regenerative Medicine through Precise Gene-editing Technology 通过精确的基因编辑技术指导再生医学
Pub Date : 2018-11-27 DOI: 10.19080/ctbeb.2018.17.555962
Diaz-Martinez Emmanuel
Regenerative medicine, an emerging area of health, is currently being explored in depth and could have a tremendous impact on improving the quality of life of the world’s population. The study of molecular mechanisms of Stem Cells has evidenced its regenerative properties, at the same time, the maturation of the precise gene-editing technology (CRISPR/Cas9), has made it possible to manipulate key regenerative properties such as self-renewal and the controlled release of trophic factors, allowing to improve the natural regenerative process in situ, among mammalian organisms.
再生医学是一个新兴的保健领域,目前正在深入探索,可能对改善世界人口的生活质量产生巨大影响。干细胞分子机制的研究已经证明了其再生特性,同时,精确基因编辑技术(CRISPR/Cas9)的成熟,使得操纵关键的再生特性,如自我更新和营养因子的控制释放成为可能,从而可以改善哺乳动物生物的原位自然再生过程。
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引用次数: 0
When Ward Stock Impacts NCHD Productivity. Assessing the Stock Issues that Impact Interns on a daily Basis in University Hospital Limerick 当沃德股票影响NCHD生产力。评估对利默里克大学医院实习生日常影响的股票问题
Pub Date : 2018-11-21 DOI: 10.19080/ctbeb.2018.17.555961
C. M.
of
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引用次数: 1
Aberrancy in CNS Signals and other Factors Related to Altered Homeostasis, Obesity and Metabolic Syndrome 中枢神经系统信号异常及与体内平衡改变、肥胖和代谢综合征相关的其他因素
Pub Date : 2018-11-20 DOI: 10.19080/CTBEB.2018.17.555960
Vinod Nikhra
‘The Obese-Obese World’: The obesity and metabolic syndrome (MetS) are a global epidemic of such magnitude that the today’s health scenario can be also influence sympathetic outflow to BAT. Conclusion - Fallouts of Neurosignal Aberrancy: The obese subjects with BMI > 30 show atrophy in the frontal lobes, anterior cingulate gyrus, hippocampus, and thalamus. MetS affects various cognitive domains including executive functioning, processing speed, and overall intellectual functioning. There is impaired vascular reactivity, endothelial dysfunction, neuro-inflammation, oxidative stress and altered brain metabolism.
“肥胖-肥胖世界”:肥胖和代谢综合征(MetS)是一种全球性流行病,其规模如此之大,以至于当今的健康状况也可能影响到交感神经向BAT的流出。结论-神经信号异常的影响:BMI为bbbb30的肥胖受试者在额叶、前扣带回、海马和丘脑中表现出萎缩。MetS影响各种认知领域,包括执行功能、处理速度和整体智力功能。血管反应性受损,内皮功能障碍,神经炎症,氧化应激和脑代谢改变。
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引用次数: 1
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Current Trends in Biomedical Engineering & Biosciences
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