Abstract:: Psoriasis is a persistent skin illness that causes dense, shimmering flakes, irritable, dry, and red patches as a result of the fast buildup of skin cells. It is an autoimmune skin condition that is incurable, non-contagious, and relapsing-remitting. Typically, a remission phase lasts one to twelve months. Psoriasis is caused by a number of cellular mechanisms, and it has been hypothesised that T lymphocytes, keratinocytes, allergen cells, Langerhans cells, natural killer cells, phagocytes, a number of Th1-type chemokines, in addition to growth factors like endothelial proliferation factor and keratinocytes growth factor, among others, are key players in the development of psoriasis. Numerous synthetic medicinal drugs have been documented to have the side effects of psoriasis. Due to the safety and accessibility, herbal medications may hold promise as possible anti-psoriatic molecules. Before creating a potential herbal drug, it is important to thoroughly examine the key players in the evolution of psoriasis, such as T-cell stimulation, transportation, and cytokinase inhibition. The purpose of this review is to investigate how psoriasis spreads and becomes activated, as well as how certain medications might exacerbate the condition and how certain plant resources may be used to treat psoriasis. To create a potent, secure, and dependable treatment, more scientific research on these herbal resources is required.
{"title":"A Critical Study on the Synthetic and Herbal Medication Pattern in the Management of Psoriasis","authors":"Shobhini Chandel, Saumya Das, Neha Neha, Vijayant Singh Chauhan","doi":"10.2174/0122150838251874231011093514","DOIUrl":"https://doi.org/10.2174/0122150838251874231011093514","url":null,"abstract":"Abstract:: Psoriasis is a persistent skin illness that causes dense, shimmering flakes, irritable, dry, and red patches as a result of the fast buildup of skin cells. It is an autoimmune skin condition that is incurable, non-contagious, and relapsing-remitting. Typically, a remission phase lasts one to twelve months. Psoriasis is caused by a number of cellular mechanisms, and it has been hypothesised that T lymphocytes, keratinocytes, allergen cells, Langerhans cells, natural killer cells, phagocytes, a number of Th1-type chemokines, in addition to growth factors like endothelial proliferation factor and keratinocytes growth factor, among others, are key players in the development of psoriasis. Numerous synthetic medicinal drugs have been documented to have the side effects of psoriasis. Due to the safety and accessibility, herbal medications may hold promise as possible anti-psoriatic molecules. Before creating a potential herbal drug, it is important to thoroughly examine the key players in the evolution of psoriasis, such as T-cell stimulation, transportation, and cytokinase inhibition. The purpose of this review is to investigate how psoriasis spreads and becomes activated, as well as how certain medications might exacerbate the condition and how certain plant resources may be used to treat psoriasis. To create a potent, secure, and dependable treatment, more scientific research on these herbal resources is required.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"2023 109","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136132888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-24DOI: 10.2174/0122150838268714231013072103
Aamir Tariq Malla, Zahid Ahmad Paul, Mohammad Akbar Dar, Mubashir Hussain Masoodi
Abstract: Plants have been used since the earliest times to manage various diseases, and many of these plants are being used as conventional remedies for various disorders today. Biologically active ingredients isolated from medicinal plants and extracts are receiving a lot of attention these days, partly because modern-day medication has a lot of side effects and somewhat because pathogenic microorganisms are becoming more resistant to antibiotics and many other treatments. Artemisia is the broadly dispersed genus of the family Asteraceae and encompasses almost five hundred species. Amongst these species, Artemisia absinthium L. is a familiar herb called Wormwood in English and Urdu, generally known as Afsanteen. In history, this species was recognized as important, and in old Europe, it was called “the most important master against all exhaustion”. A. absinthium has various benefits in treating pathological conditions such as gastric problems, fever, inflammation, and urinary disorders. The official European medicine uses A. absinthium in both allopathy and homeopathy. The herb was used to treat bladder diseases, anemia, helminthiasis, insomnia, fever, and trouble healing wounds and to treat gastrointestinal disorders in Asian and European traditional medicine. Mono and sesquiterpenes are the major pharmacologically active constituents of A. absinthium. Wormwood is a valuable resource of chemically new constituents and requires comprehensive screening approaches to emphasize the phytoconstituents and pharmacological actions at the molecular level. The core focus of this review is to provide complete information about the scientific evidence-based pharmacological activities, traditional uses, and phytoconstituents from A. absinthium. The collation of literature has been done by using references from main databases such as PubMed, Research gate, Scopes, Science Direct, Google Scholar, Chemical Abstracts, Phytochemical and Ethnobotanical Databases, Medicinal and Aromatic Plants Abstracts, classical books, and pharmacopeias.
摘要:植物最早被用来治疗各种疾病，今天许多植物被用作治疗各种疾病的常规药物。从药用植物和提取物中分离出来的生物活性成分最近受到了很多关注，部分原因是现代药物有很多副作用，部分原因是病原微生物对抗生素和许多其他治疗的耐药性越来越强。蒿属是菊科中分布广泛的属，包括近500种植物。在这些物种中，艾草(Artemisia absinthium L.)是一种在英语和乌尔都语中被称为Wormwood的常见草药，通常被称为Afsanteen。在历史上，这个物种被认为是重要的，在旧欧洲，它被称为“对抗所有疲惫的最重要的主人”。苦艾草在治疗胃病、发烧、炎症和泌尿系统疾病等病理疾病方面有多种益处。官方的欧洲医学使用苦艾草在对抗疗法和顺势疗法。在亚洲和欧洲的传统医学中，这种草药被用来治疗膀胱疾病、贫血、寄生虫病、失眠、发烧和伤口愈合困难，以及治疗胃肠道疾病。苦艾草的主要药理活性成分是单萜类和倍半萜类。艾草是一种宝贵的化学新成分资源，需要综合筛选方法来强调植物成分和分子水平上的药理作用。本文综述的核心重点是提供有关苦艾草的药理活性、传统用途和植物成分的完整信息。文献整理参考了PubMed、Research gate、Scopes、Science Direct、Google Scholar、Chemical Abstracts、Phytochemical and ethno植物学数据库、Medicinal and Aromatic Plants Abstracts、经典书籍、药典等主要数据库。
{"title":"An Update on the Pharmacological Activity and Phytochemistry of Artemisia Absinthium L.","authors":"Aamir Tariq Malla, Zahid Ahmad Paul, Mohammad Akbar Dar, Mubashir Hussain Masoodi","doi":"10.2174/0122150838268714231013072103","DOIUrl":"https://doi.org/10.2174/0122150838268714231013072103","url":null,"abstract":"Abstract: Plants have been used since the earliest times to manage various diseases, and many of these plants are being used as conventional remedies for various disorders today. Biologically active ingredients isolated from medicinal plants and extracts are receiving a lot of attention these days, partly because modern-day medication has a lot of side effects and somewhat because pathogenic microorganisms are becoming more resistant to antibiotics and many other treatments. Artemisia is the broadly dispersed genus of the family Asteraceae and encompasses almost five hundred species. Amongst these species, Artemisia absinthium L. is a familiar herb called Wormwood in English and Urdu, generally known as Afsanteen. In history, this species was recognized as important, and in old Europe, it was called “the most important master against all exhaustion”. A. absinthium has various benefits in treating pathological conditions such as gastric problems, fever, inflammation, and urinary disorders. The official European medicine uses A. absinthium in both allopathy and homeopathy. The herb was used to treat bladder diseases, anemia, helminthiasis, insomnia, fever, and trouble healing wounds and to treat gastrointestinal disorders in Asian and European traditional medicine. Mono and sesquiterpenes are the major pharmacologically active constituents of A. absinthium. Wormwood is a valuable resource of chemically new constituents and requires comprehensive screening approaches to emphasize the phytoconstituents and pharmacological actions at the molecular level. The core focus of this review is to provide complete information about the scientific evidence-based pharmacological activities, traditional uses, and phytoconstituents from A. absinthium. The collation of literature has been done by using references from main databases such as PubMed, Research gate, Scopes, Science Direct, Google Scholar, Chemical Abstracts, Phytochemical and Ethnobotanical Databases, Medicinal and Aromatic Plants Abstracts, classical books, and pharmacopeias.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"11 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135315922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Clausena indica (Dalzell) Oliv. belongs to Rutaceae family and it is native to South and South-East Asia. The plant is used in the traditional medicine to treat malaria, rheumatism, bone fracture etc. Objective: In the present review, the previous reports on C. indica concerning its ethnobotanical uses, morphological description, eco-geographical features, phytochemistry and pharmacological effects are summarized Methods: Science-Direct, PubMed, Springer, Scopus and Google-Scholar were used to find potentially relevant literature. The collected literature was analyzed and potential titles were included for screening the abstracts and checking the full texts. After screening 90 potentially interesting articles and other related literature, a reference list of about 39 articles were selected. The reviews, dissertations and other literature without any original research were excluded. Conclusion: The present review describes the ethnomedicinal uses, reported phytochemical compounds isolated from the plant species and various pharmacological properties of C. indica. Ethnomedicinal studies indicated the use of C. indica for the treatment of various diseases. Pharmacological reports showed that C. indica exhibited significant antidiabetic, antioxidant, antimicrobial, free radical scavenging, anti-gout and anticancer effects. Detailed phytochemical studies and molecular gene expression studies are required to explain the exact mechanism of action of active phytocompounds.
{"title":"A Mini Review on Ethnomedicinal uses, Phytochemistry and Pharmacological Properties of Indian Wampi Plant: Clausena indica (Dalzell) Oliv","authors":"Neenthamadathil Mohandas Krishnakumar, Stanislaus Antony Ceasar","doi":"10.2174/0122150838258642230920054729","DOIUrl":"https://doi.org/10.2174/0122150838258642230920054729","url":null,"abstract":"Background: Clausena indica (Dalzell) Oliv. belongs to Rutaceae family and it is native to South and South-East Asia. The plant is used in the traditional medicine to treat malaria, rheumatism, bone fracture etc. Objective: In the present review, the previous reports on C. indica concerning its ethnobotanical uses, morphological description, eco-geographical features, phytochemistry and pharmacological effects are summarized Methods: Science-Direct, PubMed, Springer, Scopus and Google-Scholar were used to find potentially relevant literature. The collected literature was analyzed and potential titles were included for screening the abstracts and checking the full texts. After screening 90 potentially interesting articles and other related literature, a reference list of about 39 articles were selected. The reviews, dissertations and other literature without any original research were excluded. Conclusion: The present review describes the ethnomedicinal uses, reported phytochemical compounds isolated from the plant species and various pharmacological properties of C. indica. Ethnomedicinal studies indicated the use of C. indica for the treatment of various diseases. Pharmacological reports showed that C. indica exhibited significant antidiabetic, antioxidant, antimicrobial, free radical scavenging, anti-gout and anticancer effects. Detailed phytochemical studies and molecular gene expression studies are required to explain the exact mechanism of action of active phytocompounds.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135414872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-22DOI: 10.2174/0122150838267094231002173019
Pranay Wal, Dr. Himansu Bhusan Samal, Riya Khare, Dr.Kunal Arora Arora, Mohit Soni, Shruti Rathore, Dr. Ankita Wal
Background:: The Aloe Vera plant has been used in India for several decades for the treatment of periodontal disease. The plant has been considered to have antimicrobial and antiinflammatory properties, but it is still used for the treatment of periodontitis inflammation. Objective:: The study's goal was to assess the function of Aloe vera in the treatment of periodontitis. The article summarized numerous clinical research studies, clinical trials reports, patent reports, and safety data in addition to the mechanism of action to provide an overview of Aloe Vera’s usefulness in the treatment of periodontitis. Methods:: The information for their review articles was acquired by using Google Scholar and PubMed as search engines, as well as a number of publishers, including Springer Nature, Bentham Science, Taylor & Francis, and Elsevier. ClinicalTrials.gov.in was referred to study the clinical trials data, and Google Patents was used as a search engine for collecting patent reports. Results:: Aloe Vera is useful for Periodontitis prevention and treatment due to its antiinflammatory, antibacterial, and antioxidant features. Aloe Vera can be used as an alternative to treat periodontitis and its related physiological effects such as gingivitis and mucositis, and various pre-clinical and clinical studies have been summarized that have demonstrated that using Aloe Vera significantly improved the mentioned parameters. Conclusion:: Aloe Vera is an herb that may be used to treat periodontitis and its associated negative effects. However, more preclinical and clinical research, might contribute to raising awareness and managing periodontitis.
背景:芦荟植物在印度用于治疗牙周病已有几十年的历史。该植物被认为具有抗菌和抗炎的特性，但它仍然用于治疗牙周炎炎症。目的:本研究的目的是评估芦荟在治疗牙周炎中的作用。本文总结了大量的临床研究、临床试验报告、专利报告和安全性数据以及作用机制，概述了芦荟在治疗牙周炎方面的有效性。方法:使用Google Scholar和PubMed作为搜索引擎，以及一些出版商，包括Springer Nature, Bentham Science, Taylor &弗朗西斯和爱思唯尔。ClinicalTrials.gov.in查阅临床试验数据，Google Patents作为检索引擎收集专利报告。结果:芦荟具有抗炎、抗菌和抗氧化的特点，对预防和治疗牙周炎很有用。芦荟可作为治疗牙周炎及其相关的牙龈炎、粘膜炎等生理效应的替代药物，各种临床前和临床研究已经总结表明，使用芦荟可显著改善上述参数。结论:芦荟是一种可用于治疗牙周炎及其相关负面影响的草药。然而，更多的临床前和临床研究，可能有助于提高认识和管理牙周炎。
{"title":"Aloe Vera: A Potential Herb for Periodontitis Management","authors":"Pranay Wal, Dr. Himansu Bhusan Samal, Riya Khare, Dr.Kunal Arora Arora, Mohit Soni, Shruti Rathore, Dr. Ankita Wal","doi":"10.2174/0122150838267094231002173019","DOIUrl":"https://doi.org/10.2174/0122150838267094231002173019","url":null,"abstract":"Background:: The Aloe Vera plant has been used in India for several decades for the treatment of periodontal disease. The plant has been considered to have antimicrobial and antiinflammatory properties, but it is still used for the treatment of periodontitis inflammation. Objective:: The study's goal was to assess the function of Aloe vera in the treatment of periodontitis. The article summarized numerous clinical research studies, clinical trials reports, patent reports, and safety data in addition to the mechanism of action to provide an overview of Aloe Vera’s usefulness in the treatment of periodontitis. Methods:: The information for their review articles was acquired by using Google Scholar and PubMed as search engines, as well as a number of publishers, including Springer Nature, Bentham Science, Taylor & Francis, and Elsevier. ClinicalTrials.gov.in was referred to study the clinical trials data, and Google Patents was used as a search engine for collecting patent reports. Results:: Aloe Vera is useful for Periodontitis prevention and treatment due to its antiinflammatory, antibacterial, and antioxidant features. Aloe Vera can be used as an alternative to treat periodontitis and its related physiological effects such as gingivitis and mucositis, and various pre-clinical and clinical studies have been summarized that have demonstrated that using Aloe Vera significantly improved the mentioned parameters. Conclusion:: Aloe Vera is an herb that may be used to treat periodontitis and its associated negative effects. However, more preclinical and clinical research, might contribute to raising awareness and managing periodontitis.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135462755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-20DOI: 10.2174/0122150838239182231009060653
Mohammad Hossain Mehrolhassani, Rahil Ghorbani Nia, Leila Vali, Yousef Shaabani
Introduction: Traditional medicine is based on knowledge, skills, and practices relying on the theories, beliefs, and indigenous experiences of different cultures that has a healthoriented and holistic view. With a holistic and health-oriented approach, quaternary prevention also seeks to prevent harm to the patient.Patient harm can be prevented by using efficient methods of traditional medicine and limiting the use of ineffective and harmful methods. Methods: The quantitative design of the study was conducted using a phenomenological approach among the faculty members of the Faculty of Traditional Medicine of Kerman University of Medical Sciences. Semi-structured interviews were conducted with the participation of 12 individuals selected using purposeful sampling. Content analysis was used to analyze the data. The codes were categorized based on their differences or similarities. Results: Six main themes were identified: prevention, patient benefit, quality of service, patient harm, rules and regulations, and financial burden. 18 sub-themes were extracted. Conclusion: Healthcare providers must protect their patients from the harms and costs of unnecessary diagnostic, therapeutic, and preventative measures. It is likely that adopting effective executive mechanisms, rules, and regulations focusing on the principle of patient benefit can lead to the implementation of a combination of traditional medicine and modern medicine on an extensive scale, aiming to reduce patient harm.
{"title":"Reviewing Expert Attitudes Toward Quaternary Prevention using Traditional Medicine: A Qualitative Study","authors":"Mohammad Hossain Mehrolhassani, Rahil Ghorbani Nia, Leila Vali, Yousef Shaabani","doi":"10.2174/0122150838239182231009060653","DOIUrl":"https://doi.org/10.2174/0122150838239182231009060653","url":null,"abstract":"Introduction: Traditional medicine is based on knowledge, skills, and practices relying on the theories, beliefs, and indigenous experiences of different cultures that has a healthoriented and holistic view. With a holistic and health-oriented approach, quaternary prevention also seeks to prevent harm to the patient.Patient harm can be prevented by using efficient methods of traditional medicine and limiting the use of ineffective and harmful methods. Methods: The quantitative design of the study was conducted using a phenomenological approach among the faculty members of the Faculty of Traditional Medicine of Kerman University of Medical Sciences. Semi-structured interviews were conducted with the participation of 12 individuals selected using purposeful sampling. Content analysis was used to analyze the data. The codes were categorized based on their differences or similarities. Results: Six main themes were identified: prevention, patient benefit, quality of service, patient harm, rules and regulations, and financial burden. 18 sub-themes were extracted. Conclusion: Healthcare providers must protect their patients from the harms and costs of unnecessary diagnostic, therapeutic, and preventative measures. It is likely that adopting effective executive mechanisms, rules, and regulations focusing on the principle of patient benefit can lead to the implementation of a combination of traditional medicine and modern medicine on an extensive scale, aiming to reduce patient harm.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135620251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-20DOI: 10.2174/0122150838274570231012052116
Preet Amol Singh
Background: Some of the most well-known ancient medical systems in India include Ayurveda, Yoga, Unani, Siddha, and Homoeopathy (AYUSH), whose medications are made primarily from medicinal plants gathered from forests. The Biological Diversity Act, of 2002 was created in India to carry out the 1992 United Nations Convention on Biological Diversity (CBD). The CBD aims for a sustainable, equitable, and shared distribution of benefits resulting from the use of biological resources and traditional knowledge. With one of its goals being to encourage the cultivation of medicinal plants, the Biological Diversity (Amendment) Bill, 2021, which proposes to amend the Biological Diversity Act of 2002, has been adopted by the lower house (Lok Sabha) of the Indian parliament. Objective: The goal of the study is to examine how the amendment will affect the AYUSH sector, which also happens to be the source of India's traditional medicines. Results: A distinction between cultivated and wild medicinal plants has been made, with cultivated medicinal plants being excluded from the access and benefit-sharing (ABS) mechanism upon acquiring the certificate of origin. This can give rise to false claims by the traders and manufacturers that their medicinal plants are cultivated. According to the most recent modification, the majority of traditional knowledge employed in the AYUSH systems of medicine is codified. There's a potential that the majority of people who have traditional knowledge will not be eligible for the benefits. The other argument is that eliminating AYUSH practitioners, growing medicinal plants, and codifying traditional knowledge from access and benefit sharing, would promote foreign investment in the AYUSH sector. Conclusion: This amendment must, in practice, ensure that tribes and vulnerable people profit from the sale of medicinal forest products, and decriminalising certain clauses actually advances AYUSH, and simplifies business operations. Striking a balance between encouraging economic growth and maintaining the long-term preservation of India's biodiversity is necessary.
{"title":"Effects of the Biological Diversity (Amendment) Bill, 2021 on India's AYUSH Industry","authors":"Preet Amol Singh","doi":"10.2174/0122150838274570231012052116","DOIUrl":"https://doi.org/10.2174/0122150838274570231012052116","url":null,"abstract":"Background: Some of the most well-known ancient medical systems in India include Ayurveda, Yoga, Unani, Siddha, and Homoeopathy (AYUSH), whose medications are made primarily from medicinal plants gathered from forests. The Biological Diversity Act, of 2002 was created in India to carry out the 1992 United Nations Convention on Biological Diversity (CBD). The CBD aims for a sustainable, equitable, and shared distribution of benefits resulting from the use of biological resources and traditional knowledge. With one of its goals being to encourage the cultivation of medicinal plants, the Biological Diversity (Amendment) Bill, 2021, which proposes to amend the Biological Diversity Act of 2002, has been adopted by the lower house (Lok Sabha) of the Indian parliament. Objective: The goal of the study is to examine how the amendment will affect the AYUSH sector, which also happens to be the source of India's traditional medicines. Results: A distinction between cultivated and wild medicinal plants has been made, with cultivated medicinal plants being excluded from the access and benefit-sharing (ABS) mechanism upon acquiring the certificate of origin. This can give rise to false claims by the traders and manufacturers that their medicinal plants are cultivated. According to the most recent modification, the majority of traditional knowledge employed in the AYUSH systems of medicine is codified. There's a potential that the majority of people who have traditional knowledge will not be eligible for the benefits. The other argument is that eliminating AYUSH practitioners, growing medicinal plants, and codifying traditional knowledge from access and benefit sharing, would promote foreign investment in the AYUSH sector. Conclusion: This amendment must, in practice, ensure that tribes and vulnerable people profit from the sale of medicinal forest products, and decriminalising certain clauses actually advances AYUSH, and simplifies business operations. Striking a balance between encouraging economic growth and maintaining the long-term preservation of India's biodiversity is necessary.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Ayurvedic cosmeceuticals are alluded to as products of various passable magnificence substances to shape the base in which one or more ayurvedic parts are utilized to give benefits and various ailments. The Drugs and Cosmetics Act of 1940 controls the approaches concerning the making, dealing, amassing, allotment, and importing of drugs in essentially a comparable manner to radiance care things in India. Quality control and assessment of Ayurvedic drugs must ensure the effectiveness of the drug. Given their crucial role, it involves evaluating their physical, chemical, and physiochemical qualities, as well as conducting in-vitro and in-vivo tests. Natural ingredients have consistently been our primary source of medicines, and dosage forms determine how drug molecules or plant components are delivered to the site of action within the body. Good agricultural and collection practices (GACP) rules have been given by the WHO (World Health Organization) for the differentiation and planning of regular items. There are primarily two legal regulatory bodies within the AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) sector i.e., Central Council of Indian Medicine (CCIM) and the Central Council of Homeopathy.
{"title":"Important Regulatory Guidelines on Natural Products","authors":"Abhisar Sahu, Nimisha srivastava, Devashish Jena, Aayushee Singh, Satya Kumar, Iti Chauhan","doi":"10.2174/0122150838226206230922043839","DOIUrl":"https://doi.org/10.2174/0122150838226206230922043839","url":null,"abstract":"Abstract: Ayurvedic cosmeceuticals are alluded to as products of various passable magnificence substances to shape the base in which one or more ayurvedic parts are utilized to give benefits and various ailments. The Drugs and Cosmetics Act of 1940 controls the approaches concerning the making, dealing, amassing, allotment, and importing of drugs in essentially a comparable manner to radiance care things in India. Quality control and assessment of Ayurvedic drugs must ensure the effectiveness of the drug. Given their crucial role, it involves evaluating their physical, chemical, and physiochemical qualities, as well as conducting in-vitro and in-vivo tests. Natural ingredients have consistently been our primary source of medicines, and dosage forms determine how drug molecules or plant components are delivered to the site of action within the body. Good agricultural and collection practices (GACP) rules have been given by the WHO (World Health Organization) for the differentiation and planning of regular items. There are primarily two legal regulatory bodies within the AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) sector i.e., Central Council of Indian Medicine (CCIM) and the Central Council of Homeopathy.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Woodfordia fruticosa (L.) Kurz, a member of the 'Lythraceae' family, has been used in traditional medicine to cure common diseases since ancient times. It is traditionally used to treat a variety of maladies such as the common cold, toothache, blood infection, leprosy, dysentery, wounds, rheumatic pain, fever, urinary issues, inflammation, antifertility, and menstrual problems. The huge potential and impacts of this plant have been thoroughly confirmed in in vitro and in vivo studies. The most current research on the plant Woodfordia fruticosa is critical for identifying the bioactive components responsible for its medicinal efficacy. Phytochemical studies reveal the existence of several chemicals extracted from various components of the plant, including glycosides, terpenes, flavonoids, tannins, sterols, phenolics, and essential oils. According to pharmacological studies, the plant has many medicinal properties, such as hypoglycemic, antioxidant, analgesic, hepatoprotective, antibacterial, gastric protective, and wound healing. Most of the pharmacological effects of raw extracts of this plant have been described. Only a few researchers have reported the activity of chemicals isolated from this plant. Therefore, this research will help to discover the many different medicinal properties of the plant as well as its pharmacological effects on various diseases and will show that further research is needed to explore its practical applications.
{"title":"Woodfordia fruticosa (L. Kurz): An Evidence-based Study of Its Phytochemical and Pharmacological Activity","authors":"Kuldeep Singh, Jeetendra Kumar Gupta, Devender Pathak, Shivendra Kumar, Ateet Srivastava, Avinash Kumar Mishra, Aman Patel, Harshit Prajapati","doi":"10.2174/0122150838258736231007045743","DOIUrl":"https://doi.org/10.2174/0122150838258736231007045743","url":null,"abstract":"Abstract: Woodfordia fruticosa (L.) Kurz, a member of the 'Lythraceae' family, has been used in traditional medicine to cure common diseases since ancient times. It is traditionally used to treat a variety of maladies such as the common cold, toothache, blood infection, leprosy, dysentery, wounds, rheumatic pain, fever, urinary issues, inflammation, antifertility, and menstrual problems. The huge potential and impacts of this plant have been thoroughly confirmed in in vitro and in vivo studies. The most current research on the plant Woodfordia fruticosa is critical for identifying the bioactive components responsible for its medicinal efficacy. Phytochemical studies reveal the existence of several chemicals extracted from various components of the plant, including glycosides, terpenes, flavonoids, tannins, sterols, phenolics, and essential oils. According to pharmacological studies, the plant has many medicinal properties, such as hypoglycemic, antioxidant, analgesic, hepatoprotective, antibacterial, gastric protective, and wound healing. Most of the pharmacological effects of raw extracts of this plant have been described. Only a few researchers have reported the activity of chemicals isolated from this plant. Therefore, this research will help to discover the many different medicinal properties of the plant as well as its pharmacological effects on various diseases and will show that further research is needed to explore its practical applications.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: The nature's signature in Āyurveda i.e. Doctrine of Signatures (DOS), which calls for utilizing natural substances that resemble a particular body part or organ, is consistent with the ethnopharmacological practice of choosing therapeutic plants based on their visible physical qualities. In order to promote health and treat ailments, the ancient Indian medical system known as Āyurveda employs natural ingredients including plants, minerals, and animal products. The study of conventional medicine and the application of natural products for therapeutic reasons are known as ethno-pharmacology. This review explores various research on ayurvedic herbs, their doctrinal signature, and the status of our understanding of ethno-pharmacology. However, by integrating Āyurveda plants' doctrinal signatures with ethnopharmacological methods, it might be better to comprehend the therapeutic potential of plants and create novel treatments for a range of ailments. Combining these two perspectives might assist in understanding how nature may heal and how natural medicines could improve health and wellness. It was believed that a plant containing parts that resembled portions of human bodies, animals, or other items had practical use for those parts, animals, or objects. This philosophy was shown in some of the Indian medicinal plants that are discussed in this article.
{"title":"Nature’s Signature in Ayurveda with an Ethnopharmacological Approach: A Narrative Review","authors":"Acharya Balkrishna, Shalini Mishra, Rajesh Kumar Mishra, Maneesha Rana, Shalini Singh, Vedpriya Arya","doi":"10.2174/0122150838270781231006184609","DOIUrl":"https://doi.org/10.2174/0122150838270781231006184609","url":null,"abstract":"Abstract: The nature's signature in Āyurveda i.e. Doctrine of Signatures (DOS), which calls for utilizing natural substances that resemble a particular body part or organ, is consistent with the ethnopharmacological practice of choosing therapeutic plants based on their visible physical qualities. In order to promote health and treat ailments, the ancient Indian medical system known as Āyurveda employs natural ingredients including plants, minerals, and animal products. The study of conventional medicine and the application of natural products for therapeutic reasons are known as ethno-pharmacology. This review explores various research on ayurvedic herbs, their doctrinal signature, and the status of our understanding of ethno-pharmacology. However, by integrating Āyurveda plants' doctrinal signatures with ethnopharmacological methods, it might be better to comprehend the therapeutic potential of plants and create novel treatments for a range of ailments. Combining these two perspectives might assist in understanding how nature may heal and how natural medicines could improve health and wellness. It was believed that a plant containing parts that resembled portions of human bodies, animals, or other items had practical use for those parts, animals, or objects. This philosophy was shown in some of the Indian medicinal plants that are discussed in this article.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135619999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.2174/0122150838266828231005055236
Anmol saini, Vishakha D. Saini, Renu Saharan, Suresh Kumar
Abstract: GA (Gallic acid) belongs to the phenolic molecule that is naturally present in plants, and has an assortment of medicinal benefits on inflammation, obesity, cancer, the heart, neurological system, and the proliferation of cells. In more recent research, the anti-cancer effects via biological mechanisms such as angiogenesis, migration, metastasis, cell cycle arrest, and apoptosis have been demonstrated. Anti-cancer activities of gallic acid are affected through the biological methods which involve reluctance of tumor migration, inflammation, etc. Numerous degenerative diseases, namely blood-vascular, ageing, inflammatory contagion and malignancy are brought on owing to the free radical damage because of the excess amount of free radicals produced and accretion. We carried out a comprehensive examination of the literature employing the expression of gallic acid. To review the most current advancements and clinical investigations for the pharmacological effects of gallic acid, recognized research from various reputable organizations and sites including Scopus, ClinicalTrails.gov, Science Direct, and PubMed were analyzed. This review, which offers a succinct description of gallic acid, updates the contents of clinical research and patent data, it brings forth the elaborate attainment regarding the various abundant therapeutic efficacies along with the extraction methodology of the drug that is used to obtain it, including microwave-assisted extraction and maceration extraction, among others, as well as non-chromatographic and chromatographic techniques for its isolation and quantification. Antifungal, antiulcer, antiviral, anticancer, and antibacterial properties are just a few of the pharmacological effects of naturally occurring gallic acid.
{"title":"Gallic Acid: A Wonderful Remedy in Medicinal Field","authors":"Anmol saini, Vishakha D. Saini, Renu Saharan, Suresh Kumar","doi":"10.2174/0122150838266828231005055236","DOIUrl":"https://doi.org/10.2174/0122150838266828231005055236","url":null,"abstract":"Abstract: GA (Gallic acid) belongs to the phenolic molecule that is naturally present in plants, and has an assortment of medicinal benefits on inflammation, obesity, cancer, the heart, neurological system, and the proliferation of cells. In more recent research, the anti-cancer effects via biological mechanisms such as angiogenesis, migration, metastasis, cell cycle arrest, and apoptosis have been demonstrated. Anti-cancer activities of gallic acid are affected through the biological methods which involve reluctance of tumor migration, inflammation, etc. Numerous degenerative diseases, namely blood-vascular, ageing, inflammatory contagion and malignancy are brought on owing to the free radical damage because of the excess amount of free radicals produced and accretion. We carried out a comprehensive examination of the literature employing the expression of gallic acid. To review the most current advancements and clinical investigations for the pharmacological effects of gallic acid, recognized research from various reputable organizations and sites including Scopus, ClinicalTrails.gov, Science Direct, and PubMed were analyzed. This review, which offers a succinct description of gallic acid, updates the contents of clinical research and patent data, it brings forth the elaborate attainment regarding the various abundant therapeutic efficacies along with the extraction methodology of the drug that is used to obtain it, including microwave-assisted extraction and maceration extraction, among others, as well as non-chromatographic and chromatographic techniques for its isolation and quantification. Antifungal, antiulcer, antiviral, anticancer, and antibacterial properties are just a few of the pharmacological effects of naturally occurring gallic acid.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136213247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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