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Effects of Covid-19 pandemic on the mental health of women and treatment of mental disorders in the Unani System of Medicine: An Overview 2019冠状病毒病大流行对妇女心理健康的影响和Unani医学系统中精神障碍的治疗:概述
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-05-15 DOI: 10.2174/2215083810666230515164141
Sidra, Sana Kauser Ateeque Ahmed, Sheema, N. Jahan, A. Ansari
The world miserably collapsed when the Covid-19 (Coronavirus disease) pandemic was going out of control. The ongoing crisis has damaging effects on the mental health of individuals, predominantly women, in both developed and developing countries. Women in developing countries, both as frontline workers and at home, are at increased risk of mental health problems (specifically mental disorders). A few observational studies related to the Covid-19 pandemic have reported a higher prevalence of mental health problems like stress, anxiety, depression, insomnia, fear, delirium, hysteria etc. among women compared to men. Thus, understanding the effects of the Covid-19 pandemic on women's mental health are as important to discuss as their physical health effects.The Unani System of Medicine (USM) has a holistic approach to preventing, treating, and curing mental disorders. The present article aimed to provide an overview of the effects of the Covid-19 pandemic on women's mental health and its containment measures described in classical Unani texts besides their relevance in the current outbreak.A manual literature survey of classical Unani literature such as Firdaus al hikmat, Al Qanoon fit tib, Zakheera Khwarzam Shahi, and Kamilus Sana was conducted to collect the information available on the strategic approaches of health promotion and disease prevention in Unani Medicine. To obtain the appropriate English equivalent words for Unani terms and the scientific name of the drugs, “Standard Unani Medical Terminology” and “Classification of Unani Drugs” were consulted, respectively. Many pharmacological books and papers were considered from PubMed, Google Scholar etc.According to the literature review results, Unani doctors have pushed the adoption of personalised and predictive methods for preserving health and preventing diseases. The main focus is to treat the fragile population, i.e., women affected by mental illnesses.The present article emphasizes the mental health problems among women provoked by the Covid-19 pandemic, their possible etiopathogenesis, prevention, and psychological, regimental and pharmacological management of the USM.
当Covid-19(冠状病毒病)大流行失控时,世界悲惨地崩溃了。目前的危机对发达国家和发展中国家的个人,主要是妇女的心理健康产生了破坏性影响。发展中国家的妇女,无论是作为一线工作人员还是在家中,都面临着更大的精神健康问题(特别是精神障碍)风险。一些与Covid-19大流行相关的观察性研究报告称,与男性相比,女性患压力、焦虑、抑郁、失眠、恐惧、精神错乱、歇斯底里等心理健康问题的比例更高。因此,了解Covid-19大流行对女性心理健康的影响与其对身体健康的影响一样重要。Unani医学系统(USM)采用整体方法预防、治疗和治愈精神障碍。本文旨在概述2019冠状病毒病大流行对妇女心理健康的影响,以及经典Unani文本中描述的遏制措施,以及它们与当前疫情的相关性。对《Firdaus al hikmat》、《al Qanoon fit tib》、《Zakheera Khwarzam Shahi》和《Kamilus Sana》等乌纳尼经典文献进行了手工文献调查,以收集有关乌纳尼医学促进健康和预防疾病战略方法的现有信息。为了获得乌纳尼术语的适当英文对等词和药物的学名,分别查阅了《乌纳尼标准医学术语》和《乌纳尼药物分类》。许多药理学书籍和论文被参考了PubMed,谷歌Scholar等。根据文献综述结果,Unani医生已经推动采用个性化和预测性的方法来保持健康和预防疾病。主要重点是治疗脆弱人群,即受精神疾病影响的妇女。本文重点介绍新冠肺炎大流行引发的女性心理健康问题、可能的发病机制、预防措施以及USM的心理、治疗和药理学管理。
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引用次数: 0
Role of Bioactive Compounds in the Regulation of Hemostasis: Lessons from Nature 生物活性化合物在止血调节中的作用:来自自然界的教训
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-05-08 DOI: 10.2174/2215083810666230508150817
J. Affrald. R
The maintenance of hemostasis is a crucial component of the healing process for wounds. Hemostasis may be disrupted when there is a genetic abnormality in the process of platelet production or blood coagulation. The use of herbal remedies derived from plants native to India that exhibit a broad range of physicochemical qualities is becoming more common. This study uses an electronic database to investigate the hemostatic action of commonly accessible medicinal herbs, as well as the bioactive components and potential mechanisms behind this activity. It is possible that the transformation of traditional medicine into pharmaceuticals might be facilitated by taking into account the therapeutic characteristics of spices, garden plants, and wild plants. This review discusses a variety of topics related to plants, including their bioactivities, clinical uses, Indian traditional medicinal approaches, and modern developments. It includes several herbs and spices that have therapeutic and hemostatic properties. Extensive study is required prior to the use of herbal treatments within the context of the present healthcare system. This study deals with making a strategy to discover new medical plant-based therapeutic compounds and keeping track of the ones you already have.
止血的维持是伤口愈合过程中至关重要的组成部分。当血小板产生或凝血过程中存在遗传异常时,止血可能会中断。从印度本土植物中提取的草药的使用越来越普遍,这些植物表现出广泛的物理化学特性。本研究使用一个电子数据库来研究常见草药的止血作用,以及这种作用背后的生物活性成分和潜在机制。考虑到香料、园林植物和野生植物的治疗特性,有可能促进传统医学向药物的转化。本文从植物的生物活性、临床应用、印度传统医学方法和现代发展等方面进行了综述。它包括几种具有治疗和止血特性的草药和香料。在目前医疗保健系统的背景下,在使用草药治疗之前需要进行广泛的研究。这项研究涉及制定一项策略,以发现新的药用植物性治疗化合物,并跟踪你已经拥有的化合物。
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引用次数: 0
Concept of Fasting Therapy in the Traditional Indian Medicine of Ayurveda 印度传统阿育吠陀医学中禁食疗法的概念
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-05-05 DOI: 10.2174/2215083810666230505104229
Syal Kumar, T. Rampp
Ayurveda is a traditional Indian medical practice, which has at its heart a subcontinent filled with diverse customs and ethos. Since ancient times, as considered in the Vedas, fasting has been considered to aid a man’s spiritual life as a means of purification. The body and mind constitute the substrata of diseases, and the imbalance of Vata, Pitta, Kapha, somatic Doshas, and Rajas and Tamas (mental doshas) results in various diseases. Derangement of metabolism (Agni) is a major cause of the imbalance in the abovementioned doshas. In Ayurveda, Agni refers to the complete process of metabolic activities, both at the levels of the gastrointestinal tract (GIT) and the tissues. Digestion, metabolism, and assimilation, that is, the entire process of biological conversion and utilisation, is symbolised by ‘Agni’. The concept of channels and microchannels (srotus) plays a major role in metabolic processes as particles are transported for various bodily functions through these channels.The concept of metabolic toxins (Ama) is very relevant in modern times, particularly in the treatment of many diseases including irritable bowel syndrome, ulcerative colitis, adiposity, hypercholesterolaemia, obesity, diabetes, rheumatoid arthritis, fibromyalgia, oedema, migraine, chronic fatigue syndrome, burnout syndrome, various skin diseases and psychiatric and psychosomatic diseases that occur due to weak digestion and tissue metabolism. The vitiated doshas in the body, particularly in the stomach, reduce the intensity of or impair digestive activity to cause digestive impairment and the production of metabolic toxins. They together block the channels in the body which result in various diseases. Fasting is the absence of food in the viscera or ensuring a controlled food intake and aids the digestion of metabolic toxins, kindles digestive enzymes, activates tissue metabolism, and removes the blockage in the channels.
阿育吠陀是印度的一种传统医学,其核心是一个充满多样习俗和精神的次大陆。自古以来,正如吠陀经所认为的那样,禁食被认为是帮助一个人的精神生活的一种净化手段。身体和精神构成了疾病的基础,Vata、Pitta、Kapha、躯体Doshas以及Rajas和Tamas(精神Doshas)的失衡导致了各种疾病。代谢紊乱(Agni)是上述剂量失衡的主要原因。在阿育吠陀中,Agni指的是胃肠道(GIT)和组织层面的代谢活动的完整过程。消化、代谢和同化,即生物转化和利用的整个过程,以“Agni”为象征。通道和微通道(srotus)的概念在代谢过程中发挥着重要作用,因为颗粒通过这些通道运输以实现各种身体功能。代谢毒素(Ama)的概念在现代非常相关,特别是在治疗许多疾病中,包括肠易激综合征、溃疡性结肠炎、肥胖、高胆固醇血症、肥胖、糖尿病、类风湿性关节炎、纤维肌痛、水肿、偏头痛、慢性疲劳综合征、倦怠综合征,由于消化和组织代谢较弱而发生的各种皮肤病以及精神和心身疾病。体内,特别是胃中的葡萄球菌,会降低或损害消化活动的强度,从而导致消化障碍和代谢毒素的产生。它们一起阻断了体内的通道,从而导致各种疾病。禁食是指内脏中没有食物或确保有控制的食物摄入,有助于消化代谢毒素,点燃消化酶,激活组织代谢,消除通道堵塞。
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引用次数: 0
Review on Diabetes mellitus: An insight into the current scenarios, the challenges of therapy, and application of traditional drugs 糖尿病综述:对当前情况、治疗挑战和传统药物应用的见解
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-05-01 DOI: 10.2174/2215083810666230501212125
P. Sahoo, A. Mishra, Mukesh Pandey, A. Pannu, H. K. Dewangan
Diabetes mellitus, an epidemic of the 21st century, is listed as one of the top ten causes of death around the world by the World Health Organization and is a complicated disease to deal with. Medically, a metabolic disorder characterized by elevated blood glucose levels and altered metabolism of biological macromolecules, mainly carbohydrates. Diabetes mellitus has a worldwide prevalence, and populations of all high, middle, as well as low-income countries, are affected by it. More than 400 million persons are currently living with diabetes. Many risk factors, such as lack of exercise, irregular diet, drinking, and smoking habits, as well as genetic factors, also contribute to the increased incidence of diabetes mellitus in the modern era. The conventional therapies for diabetes are based on insulin, insulin analogues, peptides, and oral hypoglycemics. The primary objective is to lower the elevated blood glucose levels and manage the distress to enhance the quality of life of the patient. The management of diabetes is very crucial to avoid complications having serious consequences such as the extra economic burden due to these complications. Conventional drug therapy has its own adverse effects, and its timely availability and cost are still an issue in many low and middle-income countries. Diabetes mellitus has been reported in various ancient kinds of literature along with various natural remedies (plants/herbals) useful in it. These plant-based remedies offer the benefits of lesser or no adverse effects, easy availability due to natural abundance, and low cost. Therefore, extensive research work is carried out in the past few decades to identify and understand the underlying principles of plant-based/herbal medicines to develop new potential lead molecules and a relatively safer, easily available and more economical alternative treatment therapy for diabetes mellitus.
糖尿病是21世纪的流行病,被世界卫生组织列为全球十大死亡原因之一,是一种复杂的疾病。医学上,一种以血糖水平升高和生物大分子(主要是碳水化合物)代谢改变为特征的代谢紊乱。糖尿病在世界范围内流行,所有高、中、低收入国家的人口都受到它的影响。目前有4亿多人患有糖尿病。许多危险因素,如缺乏运动、饮食不规律、饮酒、吸烟习惯,以及遗传因素,也导致现代糖尿病发病率增加。传统的糖尿病治疗是基于胰岛素、胰岛素类似物、多肽和口服降糖药。主要目的是降低升高的血糖水平和控制痛苦,以提高患者的生活质量。糖尿病的管理是非常重要的,以避免并发症的严重后果,如额外的经济负担,由于这些并发症。常规药物治疗本身也有副作用,而且在许多低收入和中等收入国家,及时获得药物和费用仍然是一个问题。糖尿病在各种古代文献中都有报道,并有各种自然疗法(植物/草药)对糖尿病有用。这些以植物为基础的疗法具有副作用较小或没有副作用的优点,由于天然丰富而容易获得,而且成本低。因此,在过去的几十年里,人们进行了大量的研究工作,以识别和了解植物/草药的潜在原理,以开发新的潜在的先导分子和相对更安全、更容易获得和更经济的替代糖尿病治疗方法。
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引用次数: 0
Medicinal Properties of Crotalaria burhia: A Review 牛蒡的药用特性研究进展
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-04-28 DOI: 10.2174/2215083810666230428095559
A. Wal, P. Wal, Vibha Shukla, Mohd Masih Uzzaman Khan, Khusboo Gaur, Nem Kumar Jain
Natural products have a crucial role in the discovery and development ofdrug molecules. The secondary metabolites derived from the plant have potential therapeutic valueand reveal many pharmacological effects. Crotalaria burhia Buchham, a Leguminaceae herb, ismostly present in arid parts of India, Pakistan, China, and Afghanistan. Shinio, Bhip, Bhata, Ghugato, and Ban Sutra are just a few of the names it goes by. It is used to cure gout, eczema, hydrophobia, and inflammation. Plant root porridge is used for typhoid, wounds and cuts, rheumatism,flatulence, earaches, nasal bleeding, and stone problems. The powder form of the plant is used fordigestive disorders. The plant has potent pharmacological activity and is also carcinogenic and anticarcinogenic in nature. Various phytoconstituents are present, like tannins, amino acids, alkaloids,steroids, triterpenoids, mucilage, flavonoids, gum, polyphenols, anthraquinones, carbohydrates, glycosides, and saponins. Croburhine is a novel pyrrolizidine alkaloid obtained from it. This review focuses on the existing knowledge of the phytochemistry and pharmacological action of C. burhia,which will provide broad information for a proper assessment of the plant as a medicinal agent.The experimental analysis and data reported on the species of Crotalaria were reviewedfrom 2005 to 2022. Various databases were used as article sources, like Medline and Pubmed, and aliterature review was done using the keywords Crotalaria burhia, habitat, species, pharmacologicalaction, and traditional uses.On the basis of our perception, we have stated that the species Crotalaria burhia is a goldenherb that possesses potent pharmacological activities. It is widely used as a conventional drug forthe cure of various diseases, but its active constituents need to be evaluated more for future drugdevelopment and pharmacological action.There were a total of 21 research articles about the phytochemical screening of herbs,which showed the presence of different active constituents like alkaloids, tannins, flavonoids, steroids, glycosides, mucilage, gum, polyphenols, carbohydrates, terpenoids, etc., which are responsiblefor different pharmacological activities like antioxidant, antimicrobial, anti-inflammatory, antinociceptive, antihypertensive, antitumor, and analgesic activity.
天然产物在药物分子的发现和开发中起着至关重要的作用。该植物的次生代谢产物具有潜在的治疗价值,并显示出许多药理作用。牛蒡是豆科草本植物,主要分布在印度、巴基斯坦、中国和阿富汗的干旱地区。Shinio、Bhip、Bhata、Ghugato和Ban Sutra只是它的几个名字。它用于治疗痛风、湿疹、狂犬病和炎症。植物根粥用于治疗伤寒、伤口和割伤、风湿病、胀气、耳痛、鼻出血和结石。这种植物的粉末状物用于消化障碍。该植物具有强大的药理活性,在自然界中也具有致癌和抗癌作用。存在各种植物成分,如单宁、氨基酸、生物碱、类固醇、三萜类、粘液、类黄酮、树胶、多酚、蒽醌、碳水化合物、糖苷和皂苷。Croburhine是从中提取的一种新的吡咯里嗪生物碱。本文综述了对C.burhia的植物化学和药理作用的现有知识,为正确评价该植物的药用价值提供了广泛的信息。综述了2005年至2022年对该属植物的实验分析和资料。各种数据库被用作文章来源,如Medline和Pubmed,并使用关键词Crotalaria burhia、栖息地、物种、药理作用和传统用途进行了文献综述。根据我们的认识,我们已经表明,禾谷属植物是一种具有强大药理活性的金黄色葡萄。它作为一种治疗各种疾病的常规药物被广泛使用,但其活性成分有待于进一步的药物开发和药理作用评估。共有21篇关于草药植物化学筛选的研究文章,显示了生物碱、单宁、黄酮类化合物、类固醇、糖苷、粘液、树胶、多酚、碳水化合物、萜类化合物等不同的活性成分的存在,这些成分对抗氧化、抗菌、抗炎、镇痛等不同的药理活性有反应,抗高血压、抗肿瘤和镇痛活性。
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引用次数: 0
The Effect of Date Palm (Phoenix dactylifera L.) Pollen on the Serum Levels of Testosterone, Luteinizing, and Follicle Stimulating Hormones in Men 枣棕(Phoenix dactylifera L.)的药效花粉对男性血清睾酮、黄体生成素和促卵泡激素水平的影响
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-04-28 DOI: 10.2174/2215083810666230428100103
Majid Mirzaei, Azizeh Farshbaf Khalili, M. Karimi, Firoozeh Akbari Asbagh, Majid Safavi, M. Yekaninejad, R. Rahimi, G. Pourmand
Date Palm Pollen (DPP) has traditionally been used to increase sexualability and fertility. In several animal studies, the effects of this herbal medicine on testosterone,luteinizing hormone (LH), and follicle-stimulating hormone (FSH) have been shown.This study was conducted to evaluate the effects of this drug on the serum levels oftestosterone, LH, and FSH in men.In this semi-experimental study, a daily dose of 6 g dry powder of DPP in two separatedoses (3 g every 12 hours) was administered orally to 30 eligible men for three months. Thechanges in mean serum levels of hormones were statistically evaluated after the interventioncompared to the baseline. The serum concentration of the hormones was assayed through theenzyme-linked immunosorbent assay method. Data were analyzed using paired t-tests.After recruitment, among 30 participants, 24 men received the intervention and finallywere analyzed. The mean (SD) age and body mass index of participants were 32.85 (0.43) years and26.5 (0.5) kg/m2. DPP significantly increased the serum levels of testosterone (from 5.31±0.40ng/mlto 6.88±0.71 ng/ml; p=0.019) but did not affect the serum levels of FSH (from 4.31±0.50 IU/L to4.70±0.61 IU/L; p=0.511). It also significantly decreased the serum levels of LH (from 5.65±0.81IU/L to 4.52±0.90 IU/L; p= 0.033). There were no reported side effects.The results indicated an increasing effect of DPP on serum testosterone and decreasingeffect on serum LH. However, DPP had no significant effect on FSH serum levels.
椰枣花粉(DPP)传统上被用来提高性能力和生育能力。在一些动物研究中,这种草药对睾丸激素、黄体生成素(LH)和卵泡刺激素(FSH)的影响已经被证明。本研究旨在评估该药对男性血清睾酮、黄体生成素和卵泡刺激素水平的影响。在这项半实验研究中,30名符合条件的男性每天口服6克DPP干粉,分两剂(每12小时3克),为期3个月。与基线相比,干预后平均血清激素水平的变化进行统计学评估。采用酶联免疫吸附法测定血清激素浓度。数据分析采用配对t检验。招募后,在30名参与者中,有24名男性接受了干预,并最终进行了分析。参与者的平均(SD)年龄和体重指数分别为32.85(0.43)岁和26.5 (0.5)kg/m2。DPP显著提高血清睾酮水平(由5.31±0.40ng/ml提高至6.88±0.71 ng/ml;p=0.019),但不影响血清FSH水平(从4.31±0.50 IU/L到4.70±0.61 IU/L;p = 0.511)。血清LH水平由5.65±0.81IU/L降至4.52±0.90 IU/L;p = 0.033)。没有副作用的报道。结果表明,DPP对血清睾酮的影响增加,对血清LH的影响降低。DPP对血清FSH水平无显著影响。
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引用次数: 0
Heat Therapy: Concept, Mechanism and Application in Unani Medicine 热疗法:概念、机制及在乌纳尼医学中的应用
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-04-27 DOI: 10.2174/2215083810666230427113538
Amanullah, Shamim, A. Sayeed, Merajul Haque, Asim Ali Khan
Application of heat either generalised or localised is among various means employed in Unani medicine for promoting health, preventing as well as treating diseases. The concept of hotness (Ḥarārat) and application of physical heat have been in vogue during different periods of human civilization and it exists even today with certain modifications.Unani medicine offers various methods for the application of mild to moderate heat that includes Turkish bath (Ḥammām), massage (Dalk), cupping (Ḥijāma), sitz bath (Ābzan), inducing diaphoresis (Ta‘rīq), douche (Naṭūl), vapour bath (Inkibāb) and footbath (Pāshoya).Heating modalities are commonly used by Unani physicians for relieving pain and stiffness, relaxing muscles, increasing blood circulation, liquefying the sticky and adherent humours lodged in the peripheral tissues and reducing inflammation. Application of severe heat also finds a place among various modes of treatment mentioned in Unani medicine. Cauterisation (Kayy) is the mode that is employed for the stoppage of bleeding, removing putrefactive matter and destroying lesions.Unani medicine offers classical methods and instruments for heat therapy used for centuries for the promotion of health, prevention and management of diseases. Heat therapy has been found considerably effective in managing certain health problems and diseases.
在Unani医学中,广泛或局部应用热量是促进健康、预防和治疗疾病的各种手段之一。热的概念(Ḥarārat)和物理热的应用在人类文明的不同时期都很流行,即使在今天也有一些变化。Unani medicine提供了各种轻度至中度高温的应用方法,包括土耳其浴(Ḥammām)、按摩(Dalk)、拔罐(Ḥijāma),坐浴(Ābzan),诱导发汗(Ta'rīq),浇(Naṭ蒸汽浴(Inkibāb)和足浴(Pāshoya)。Unani医生通常使用加热方式来缓解疼痛和僵硬,放松肌肉,增加血液循环,液化周围组织中的粘性和粘附性体液,减少炎症。在Unani医学中提到的各种治疗模式中,严重高温的应用也占有一席之地。烧灼(Kayy)是一种用于止血、清除腐败物质和破坏病变的模式。Unani医学提供了几个世纪以来用于促进健康、预防和管理疾病的经典热疗方法和仪器。已经发现热疗在治疗某些健康问题和疾病方面相当有效。
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引用次数: 0
The effect of the seed of Descurainia Sophia on functional constipation in Iranian women aged 50-70 years: a randomized controlled trial Descurania Sophia种子对50-70岁伊朗妇女功能性便秘的影响:一项随机对照试验
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-04-19 DOI: 10.2174/2215083810666230419091747
Peiman Alesheikh, M. Tabatabaeichehr, H. Mortazavi, Seyed-Javad Pournaghi, J. Kasaian, Barmak Yaaghoobian, H. Akbari, Neda Kheivegi
Constipation in older adults is a common issue and is more prevalent in women. The current study aimed to assess the effectiveness of the seed of Descurainia Sophia as an herbal medicine on the severity of constipation in older women.Totally, sixty-four women aged between 50 to 70 participated in the study. The study used a randomized controlled trial to investigate the effectiveness of the seed of Descurainia Sophia on constipation. Data were collected using a constipation assessment scale and analyzed using independent samples t-test and gain score procedure.Results showed that taking a mixture of water and seeds of Descurainia Sophia significantly reduces constipation severity in older women. It was concluded that the seed of Descurainia Sophia is a safe and effective alternative for treating constipation in older women.
老年人便秘是一个常见问题,在女性中更为普遍。目前的研究旨在评估Descurania Sophia种子作为一种草药对老年女性便秘严重程度的有效性。共有64名年龄在50至70岁之间的女性参与了这项研究。该研究采用了一项随机对照试验来研究Descurania Sophia种子治疗便秘的有效性。使用便秘评估量表收集数据,并使用独立样本t检验和增益评分程序进行分析。结果表明,服用水和Descurania Sophia种子的混合物可以显著降低老年女性便秘的严重程度。结论表明,Descurania Sophia种子是治疗老年女性便秘的安全有效的替代品。
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引用次数: 0
A Review of Current Research on Traditional Medicines for the Treatment of Gastrointestinal and Biliary Disorders 传统药物治疗胃肠及胆道疾病的研究进展
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-04-18 DOI: 10.2174/2215083810666230418114504
Dharmendra Jain, Monika Vishwakarma, Akash Patel
Gastrointestinal (GI) and biliary disorders are the most commonly known health issues for people in the present time as a consequence of modern lifestyle, eating habits, stress, and many other conditions. The usage of traditional substances has been phased out over time, resulting in an increase in the occurrence of numerous diseases and a decrease in immunity. Therefore, in the current scenario, traditional medicine is increasingly being used to treat and manage diseases worldwide. Traditional medical systems of India, China, and Africa are the most frequently used today. Indian medicinal system includes the Ayurveda, Siddha, and Unani systems of medicine. Ayurveda is the most antique system of medicine, which relies on the usage of plant-based formulations. Herbal medicines are used nowadays by up to half of the world's population. Phytomedicines isolated from plants contain a wide variety of bioactive components that can have both negative and positive effects. Many herbal plants, such as Acacia, Aloe, Carum, Rose, Funnel, etc., are proven to be effective as phytomedicines that are effective for the cure of gastrointestinal and biliary problems. The available pharmacological therapeutic drugs often have efficacy but are associated with many adverse effects. To minimize the adverse effects, the use of phytomedicines can be the best possible alternative. In this study, a review of some of the most frequently used traditional herbal medicine isolates with their proven pharmacological activity and novel drug delivery systems for the proper delivery of isolates is presented. Moreover, currently available herbal-marketed formulations are also highlighted.
由于现代生活方式、饮食习惯、压力和许多其他条件的影响,胃肠道和胆道疾病是当今人们最常见的健康问题。随着时间的推移,传统物质的使用已被逐步淘汰,导致许多疾病的发病率增加,免疫力下降。因此,在目前的情况下,传统医学越来越多地被用于治疗和管理世界各地的疾病。印度、中国和非洲的传统医疗系统是当今最常用的。印度的医学体系包括阿育吠陀、悉达陀和乌纳尼医学体系。阿育吠陀是最古老的医学体系,它依赖于植物配方的使用。如今,世界上多达一半的人口都在使用草药。从植物中分离出来的植物药含有各种各样的生物活性成分,可以有负面和积极的影响。许多草本植物,如金合欢、芦荟、卡鲁姆、玫瑰、漏斗等,被证明是有效的植物药,对治疗胃肠道和胆道问题有效。现有的药理学治疗药物往往有疗效,但有许多不良反应。为了尽量减少副作用,使用植物药可能是最好的选择。在本研究中,回顾了一些最常用的传统草药分离物及其已证实的药理活性和用于适当递送分离物的新型药物递送系统。此外,还强调了目前可获得的草药销售配方。
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引用次数: 0
A Comprehensive Review on Biological and Chemical Diversity in Aesculus L. Genus (Sapindaceae) 七叶树属(无患子科)生物化学多样性研究综述
IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2023-04-17 DOI: 10.2174/2215083810666230417115041
Mamta B. Shah, Rutvi Shah, Dhyey Salot, D. Shah, Dhruvil Shah, Rajvi K Shah, Preeti D. Verma
Aesculus L. is a genus of 12 to 19 woody species, representing one of the most acclaimed examples of inter-continental incoherence of the plants native to temperate regions of the Northern Hemisphere. It is traditionally valued in Ayurveda and the Chinese system of medicine for its various species that possess antitumor, cardioprotective, anti-inflammatory and neuroprotective activities. Current studies on this genus have revealed the presence of specific saponins with a multi-spectrum of pharmacological actions and therapeutic applications. A repertoire of literature related to the biological, taxonomical, phytochemical and ethnopharmacological aspects of Aesculus genus and its uses in different indigenous populations was explored. An inventory of all the species of this genus that were found to be useful as per ethnopharmacological literature was prepared. The ethnobotany, phytochemistry and pharmacology of the individual species are outlined in this review. The extensive information cited here has adduced the likely areas where the important species of this genus can illustrate significant therapeutic intervention in the management of chronic disorders including diabetes, hypercholesterolemia and cancer. The wide range of its pharmacological actions is attributed to the distinct phytochemicals occurring in the species, especially the triterpenoidal saponins like aescin. This review amplifies the recent studies on phytochemical and pharmacological aspects, which alludes that these species have noteworthy therapeutic potential.
七叶树属(Aesculus L.)是一个由12至19种木本植物组成的属,是北半球温带植物在大陆间不连贯的最著名例子之一。传统上,它在阿育吠陀和中国医学体系中受到重视,因为它的种类繁多,具有抗肿瘤、心脏保护、抗炎和神经保护活性。目前对该属的研究已经揭示了具有多种药理作用和治疗应用的特异性皂苷的存在。探索了一系列与七叶树属的生物学、分类学、植物化学和民族药理学方面及其在不同土著群体中的应用有关的文献。根据民族药理学文献,编制了该属所有有用物种的清单。本文概述了该物种的民族植物学、植物化学和药理学。本文引用的大量信息列举了本属重要物种可能在糖尿病、高胆固醇血症和癌症等慢性疾病管理中发挥重要治疗作用的领域。其广泛的药理作用归因于该物种中存在的不同植物化学物质,尤其是七叶皂苷等三萜皂苷。这篇综述放大了最近在植物化学和药理学方面的研究,暗示这些物种具有值得注意的治疗潜力。
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Current Traditional Medicine
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