Pub Date : 2023-05-15DOI: 10.2174/2215083810666230515164141
Sidra, Sana Kauser Ateeque Ahmed, Sheema, N. Jahan, A. Ansari
The world miserably collapsed when the Covid-19 (Coronavirus disease) pandemic was going out of control. The ongoing crisis has damaging effects on the mental health of individuals, predominantly women, in both developed and developing countries. Women in developing countries, both as frontline workers and at home, are at increased risk of mental health problems (specifically mental disorders). A few observational studies related to the Covid-19 pandemic have reported a higher prevalence of mental health problems like stress, anxiety, depression, insomnia, fear, delirium, hysteria etc. among women compared to men. Thus, understanding the effects of the Covid-19 pandemic on women's mental health are as important to discuss as their physical health effects. The Unani System of Medicine (USM) has a holistic approach to preventing, treating, and curing mental disorders. The present article aimed to provide an overview of the effects of the Covid-19 pandemic on women's mental health and its containment measures described in classical Unani texts besides their relevance in the current outbreak. A manual literature survey of classical Unani literature such as Firdaus al hikmat, Al Qanoon fit tib, Zakheera Khwarzam Shahi, and Kamilus Sana was conducted to collect the information available on the strategic approaches of health promotion and disease prevention in Unani Medicine. To obtain the appropriate English equivalent words for Unani terms and the scientific name of the drugs, “Standard Unani Medical Terminology” and “Classification of Unani Drugs” were consulted, respectively. Many pharmacological books and papers were considered from PubMed, Google Scholar etc. According to the literature review results, Unani doctors have pushed the adoption of personalised and predictive methods for preserving health and preventing diseases. The main focus is to treat the fragile population, i.e., women affected by mental illnesses. The present article emphasizes the mental health problems among women provoked by the Covid-19 pandemic, their possible etiopathogenesis, prevention, and psychological, regimental and pharmacological management of the USM.
当Covid-19(冠状病毒病)大流行失控时,世界悲惨地崩溃了。目前的危机对发达国家和发展中国家的个人,主要是妇女的心理健康产生了破坏性影响。发展中国家的妇女,无论是作为一线工作人员还是在家中,都面临着更大的精神健康问题(特别是精神障碍)风险。一些与Covid-19大流行相关的观察性研究报告称,与男性相比,女性患压力、焦虑、抑郁、失眠、恐惧、精神错乱、歇斯底里等心理健康问题的比例更高。因此,了解Covid-19大流行对女性心理健康的影响与其对身体健康的影响一样重要。Unani医学系统(USM)采用整体方法预防、治疗和治愈精神障碍。本文旨在概述2019冠状病毒病大流行对妇女心理健康的影响,以及经典Unani文本中描述的遏制措施,以及它们与当前疫情的相关性。对《Firdaus al hikmat》、《al Qanoon fit tib》、《Zakheera Khwarzam Shahi》和《Kamilus Sana》等乌纳尼经典文献进行了手工文献调查,以收集有关乌纳尼医学促进健康和预防疾病战略方法的现有信息。为了获得乌纳尼术语的适当英文对等词和药物的学名,分别查阅了《乌纳尼标准医学术语》和《乌纳尼药物分类》。许多药理学书籍和论文被参考了PubMed,谷歌Scholar等。根据文献综述结果,Unani医生已经推动采用个性化和预测性的方法来保持健康和预防疾病。主要重点是治疗脆弱人群,即受精神疾病影响的妇女。本文重点介绍新冠肺炎大流行引发的女性心理健康问题、可能的发病机制、预防措施以及USM的心理、治疗和药理学管理。
{"title":"Effects of Covid-19 pandemic on the mental health of women and treatment of mental disorders in the Unani System of Medicine: An Overview","authors":"Sidra, Sana Kauser Ateeque Ahmed, Sheema, N. Jahan, A. Ansari","doi":"10.2174/2215083810666230515164141","DOIUrl":"https://doi.org/10.2174/2215083810666230515164141","url":null,"abstract":"\u0000\u0000The world miserably collapsed when the Covid-19 (Coronavirus disease) pandemic was going out of control. The ongoing crisis has damaging effects on the mental health of individuals, predominantly women, in both developed and developing countries. Women in developing countries, both as frontline workers and at home, are at increased risk of mental health problems (specifically mental disorders). A few observational studies related to the Covid-19 pandemic have reported a higher prevalence of mental health problems like stress, anxiety, depression, insomnia, fear, delirium, hysteria etc. among women compared to men. Thus, understanding the effects of the Covid-19 pandemic on women's mental health are as important to discuss as their physical health effects.\u0000\u0000\u0000\u0000The Unani System of Medicine (USM) has a holistic approach to preventing, treating, and curing mental disorders. The present article aimed to provide an overview of the effects of the Covid-19 pandemic on women's mental health and its containment measures described in classical Unani texts besides their relevance in the current outbreak.\u0000\u0000\u0000\u0000A manual literature survey of classical Unani literature such as Firdaus al hikmat, Al Qanoon fit tib, Zakheera Khwarzam Shahi, and Kamilus Sana was conducted to collect the information available on the strategic approaches of health promotion and disease prevention in Unani Medicine. To obtain the appropriate English equivalent words for Unani terms and the scientific name of the drugs, “Standard Unani Medical Terminology” and “Classification of Unani Drugs” were consulted, respectively. Many pharmacological books and papers were considered from PubMed, Google Scholar etc.\u0000\u0000\u0000\u0000According to the literature review results, Unani doctors have pushed the adoption of personalised and predictive methods for preserving health and preventing diseases. The main focus is to treat the fragile population, i.e., women affected by mental illnesses.\u0000\u0000\u0000\u0000The present article emphasizes the mental health problems among women provoked by the Covid-19 pandemic, their possible etiopathogenesis, prevention, and psychological, regimental and pharmacological management of the USM.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46778959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-08DOI: 10.2174/2215083810666230508150817
J. Affrald. R
The maintenance of hemostasis is a crucial component of the healing process for wounds. Hemostasis may be disrupted when there is a genetic abnormality in the process of platelet production or blood coagulation. The use of herbal remedies derived from plants native to India that exhibit a broad range of physicochemical qualities is becoming more common. This study uses an electronic database to investigate the hemostatic action of commonly accessible medicinal herbs, as well as the bioactive components and potential mechanisms behind this activity. It is possible that the transformation of traditional medicine into pharmaceuticals might be facilitated by taking into account the therapeutic characteristics of spices, garden plants, and wild plants. This review discusses a variety of topics related to plants, including their bioactivities, clinical uses, Indian traditional medicinal approaches, and modern developments. It includes several herbs and spices that have therapeutic and hemostatic properties. Extensive study is required prior to the use of herbal treatments within the context of the present healthcare system. This study deals with making a strategy to discover new medical plant-based therapeutic compounds and keeping track of the ones you already have.
{"title":"Role of Bioactive Compounds in the Regulation of Hemostasis: Lessons from Nature","authors":"J. Affrald. R","doi":"10.2174/2215083810666230508150817","DOIUrl":"https://doi.org/10.2174/2215083810666230508150817","url":null,"abstract":"\u0000\u0000The maintenance of hemostasis is a crucial component of the healing process for wounds. Hemostasis may be disrupted when there is a genetic abnormality in the process of platelet production or blood coagulation. The use of herbal remedies derived from plants native to India that exhibit a broad range of physicochemical qualities is becoming more common. This study uses an electronic database to investigate the hemostatic action of commonly accessible medicinal herbs, as well as the bioactive components and potential mechanisms behind this activity. It is possible that the transformation of traditional medicine into pharmaceuticals might be facilitated by taking into account the therapeutic characteristics of spices, garden plants, and wild plants. This review discusses a variety of topics related to plants, including their bioactivities, clinical uses, Indian traditional medicinal approaches, and modern developments. It includes several herbs and spices that have therapeutic and hemostatic properties. Extensive study is required prior to the use of herbal treatments within the context of the present healthcare system. This study deals with making a strategy to discover new medical plant-based therapeutic compounds and keeping track of the ones you already have.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46223988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-05DOI: 10.2174/2215083810666230505104229
Syal Kumar, T. Rampp
Ayurveda is a traditional Indian medical practice, which has at its heart a subcontinent filled with diverse customs and ethos. Since ancient times, as considered in the Vedas, fasting has been considered to aid a man’s spiritual life as a means of purification. The body and mind constitute the substrata of diseases, and the imbalance of Vata, Pitta, Kapha, somatic Doshas, and Rajas and Tamas (mental doshas) results in various diseases. Derangement of metabolism (Agni) is a major cause of the imbalance in the abovementioned doshas. In Ayurveda, Agni refers to the complete process of metabolic activities, both at the levels of the gastrointestinal tract (GIT) and the tissues. Digestion, metabolism, and assimilation, that is, the entire process of biological conversion and utilisation, is symbolised by ‘Agni’. The concept of channels and microchannels (srotus) plays a major role in metabolic processes as particles are transported for various bodily functions through these channels. The concept of metabolic toxins (Ama) is very relevant in modern times, particularly in the treatment of many diseases including irritable bowel syndrome, ulcerative colitis, adiposity, hypercholesterolaemia, obesity, diabetes, rheumatoid arthritis, fibromyalgia, oedema, migraine, chronic fatigue syndrome, burnout syndrome, various skin diseases and psychiatric and psychosomatic diseases that occur due to weak digestion and tissue metabolism. The vitiated doshas in the body, particularly in the stomach, reduce the intensity of or impair digestive activity to cause digestive impairment and the production of metabolic toxins. They together block the channels in the body which result in various diseases. Fasting is the absence of food in the viscera or ensuring a controlled food intake and aids the digestion of metabolic toxins, kindles digestive enzymes, activates tissue metabolism, and removes the blockage in the channels.
{"title":"Concept of Fasting Therapy in the Traditional Indian Medicine of Ayurveda","authors":"Syal Kumar, T. Rampp","doi":"10.2174/2215083810666230505104229","DOIUrl":"https://doi.org/10.2174/2215083810666230505104229","url":null,"abstract":"\u0000\u0000Ayurveda is a traditional Indian medical practice, which has at its heart a subcontinent filled with diverse customs and ethos. Since ancient times, as considered in the Vedas, fasting has been considered to aid a man’s spiritual life as a means of purification. The body and mind constitute the substrata of diseases, and the imbalance of Vata, Pitta, Kapha, somatic Doshas, and Rajas and Tamas (mental doshas) results in various diseases. Derangement of metabolism (Agni) is a major cause of the imbalance in the abovementioned doshas. In Ayurveda, Agni refers to the complete process of metabolic activities, both at the levels of the gastrointestinal tract (GIT) and the tissues. Digestion, metabolism, and assimilation, that is, the entire process of biological conversion and utilisation, is symbolised by ‘Agni’. The concept of channels and microchannels (srotus) plays a major role in metabolic processes as particles are transported for various bodily functions through these channels.\u0000The concept of metabolic toxins (Ama) is very relevant in modern times, particularly in the treatment of many diseases including irritable bowel syndrome, ulcerative colitis, adiposity, hypercholesterolaemia, obesity, diabetes, rheumatoid arthritis, fibromyalgia, oedema, migraine, chronic fatigue syndrome, burnout syndrome, various skin diseases and psychiatric and psychosomatic diseases that occur due to weak digestion and tissue metabolism. The vitiated doshas in the body, particularly in the stomach, reduce the intensity of or impair digestive activity to cause digestive impairment and the production of metabolic toxins. They together block the channels in the body which result in various diseases. Fasting is the absence of food in the viscera or ensuring a controlled food intake and aids the digestion of metabolic toxins, kindles digestive enzymes, activates tissue metabolism, and removes the blockage in the channels.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47580504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.2174/2215083810666230501212125
P. Sahoo, A. Mishra, Mukesh Pandey, A. Pannu, H. K. Dewangan
Diabetes mellitus, an epidemic of the 21st century, is listed as one of the top ten causes of death around the world by the World Health Organization and is a complicated disease to deal with. Medically, a metabolic disorder characterized by elevated blood glucose levels and altered metabolism of biological macromolecules, mainly carbohydrates. Diabetes mellitus has a worldwide prevalence, and populations of all high, middle, as well as low-income countries, are affected by it. More than 400 million persons are currently living with diabetes. Many risk factors, such as lack of exercise, irregular diet, drinking, and smoking habits, as well as genetic factors, also contribute to the increased incidence of diabetes mellitus in the modern era. The conventional therapies for diabetes are based on insulin, insulin analogues, peptides, and oral hypoglycemics. The primary objective is to lower the elevated blood glucose levels and manage the distress to enhance the quality of life of the patient. The management of diabetes is very crucial to avoid complications having serious consequences such as the extra economic burden due to these complications. Conventional drug therapy has its own adverse effects, and its timely availability and cost are still an issue in many low and middle-income countries. Diabetes mellitus has been reported in various ancient kinds of literature along with various natural remedies (plants/herbals) useful in it. These plant-based remedies offer the benefits of lesser or no adverse effects, easy availability due to natural abundance, and low cost. Therefore, extensive research work is carried out in the past few decades to identify and understand the underlying principles of plant-based/herbal medicines to develop new potential lead molecules and a relatively safer, easily available and more economical alternative treatment therapy for diabetes mellitus.
{"title":"Review on Diabetes mellitus: An insight into the current scenarios, the challenges of therapy, and application of traditional drugs","authors":"P. Sahoo, A. Mishra, Mukesh Pandey, A. Pannu, H. K. Dewangan","doi":"10.2174/2215083810666230501212125","DOIUrl":"https://doi.org/10.2174/2215083810666230501212125","url":null,"abstract":"\u0000\u0000Diabetes mellitus, an epidemic of the 21st century, is listed as one of the top ten causes of death around the world by the World Health Organization and is a complicated disease to deal with. Medically, a metabolic disorder characterized by elevated blood glucose levels and altered metabolism of biological macromolecules, mainly carbohydrates. Diabetes mellitus has a worldwide prevalence, and populations of all high, middle, as well as low-income countries, are affected by it. More than 400 million persons are currently living with diabetes. Many risk factors, such as lack of exercise, irregular diet, drinking, and smoking habits, as well as genetic factors, also contribute to the increased incidence of diabetes mellitus in the modern era. The conventional therapies for diabetes are based on insulin, insulin analogues, peptides, and oral hypoglycemics. The primary objective is to lower the elevated blood glucose levels and manage the distress to enhance the quality of life of the patient. The management of diabetes is very crucial to avoid complications having serious consequences such as the extra economic burden due to these complications. Conventional drug therapy has its own adverse effects, and its timely availability and cost are still an issue in many low and middle-income countries. Diabetes mellitus has been reported in various ancient kinds of literature along with various natural remedies (plants/herbals) useful in it. These plant-based remedies offer the benefits of lesser or no adverse effects, easy availability due to natural abundance, and low cost. Therefore, extensive research work is carried out in the past few decades to identify and understand the underlying principles of plant-based/herbal medicines to develop new potential lead molecules and a relatively safer, easily available and more economical alternative treatment therapy for diabetes mellitus.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45434908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-28DOI: 10.2174/2215083810666230428095559
A. Wal, P. Wal, Vibha Shukla, Mohd Masih Uzzaman Khan, Khusboo Gaur, Nem Kumar Jain
Natural products have a crucial role in the discovery and development of drug molecules. The secondary metabolites derived from the plant have potential therapeutic value and reveal many pharmacological effects. Crotalaria burhia Buchham, a Leguminaceae herb, is mostly present in arid parts of India, Pakistan, China, and Afghanistan. Shinio, Bhip, Bhata, Ghugato, and Ban Sutra are just a few of the names it goes by. It is used to cure gout, eczema, hydrophobia, and inflammation. Plant root porridge is used for typhoid, wounds and cuts, rheumatism, flatulence, earaches, nasal bleeding, and stone problems. The powder form of the plant is used for digestive disorders. The plant has potent pharmacological activity and is also carcinogenic and anticarcinogenic in nature. Various phytoconstituents are present, like tannins, amino acids, alkaloids, steroids, triterpenoids, mucilage, flavonoids, gum, polyphenols, anthraquinones, carbohydrates, glycosides, and saponins. Croburhine is a novel pyrrolizidine alkaloid obtained from it. This review focuses on the existing knowledge of the phytochemistry and pharmacological action of C. burhia, which will provide broad information for a proper assessment of the plant as a medicinal agent. The experimental analysis and data reported on the species of Crotalaria were reviewed from 2005 to 2022. Various databases were used as article sources, like Medline and Pubmed, and a literature review was done using the keywords Crotalaria burhia, habitat, species, pharmacological action, and traditional uses. On the basis of our perception, we have stated that the species Crotalaria burhia is a golden herb that possesses potent pharmacological activities. It is widely used as a conventional drug for the cure of various diseases, but its active constituents need to be evaluated more for future drug development and pharmacological action. There were a total of 21 research articles about the phytochemical screening of herbs, which showed the presence of different active constituents like alkaloids, tannins, flavonoids, steroids, glycosides, mucilage, gum, polyphenols, carbohydrates, terpenoids, etc., which are responsible for different pharmacological activities like antioxidant, antimicrobial, anti-inflammatory, antinociceptive, antihypertensive, antitumor, and analgesic activity.
{"title":"Medicinal Properties of Crotalaria burhia: A Review","authors":"A. Wal, P. Wal, Vibha Shukla, Mohd Masih Uzzaman Khan, Khusboo Gaur, Nem Kumar Jain","doi":"10.2174/2215083810666230428095559","DOIUrl":"https://doi.org/10.2174/2215083810666230428095559","url":null,"abstract":"\u0000\u0000Natural products have a crucial role in the discovery and development of\u0000drug molecules. The secondary metabolites derived from the plant have potential therapeutic value\u0000and reveal many pharmacological effects. Crotalaria burhia Buchham, a Leguminaceae herb, is\u0000mostly present in arid parts of India, Pakistan, China, and Afghanistan. Shinio, Bhip, Bhata, Ghugato, and Ban Sutra are just a few of the names it goes by. It is used to cure gout, eczema, hydrophobia, and inflammation. Plant root porridge is used for typhoid, wounds and cuts, rheumatism,\u0000flatulence, earaches, nasal bleeding, and stone problems. The powder form of the plant is used for\u0000digestive disorders. The plant has potent pharmacological activity and is also carcinogenic and anticarcinogenic in nature. Various phytoconstituents are present, like tannins, amino acids, alkaloids,\u0000steroids, triterpenoids, mucilage, flavonoids, gum, polyphenols, anthraquinones, carbohydrates, glycosides, and saponins. Croburhine is a novel pyrrolizidine alkaloid obtained from it. This review focuses on the existing knowledge of the phytochemistry and pharmacological action of C. burhia,\u0000which will provide broad information for a proper assessment of the plant as a medicinal agent.\u0000\u0000\u0000\u0000The experimental analysis and data reported on the species of Crotalaria were reviewed\u0000from 2005 to 2022. Various databases were used as article sources, like Medline and Pubmed, and a\u0000literature review was done using the keywords Crotalaria burhia, habitat, species, pharmacological\u0000action, and traditional uses.\u0000\u0000\u0000\u0000On the basis of our perception, we have stated that the species Crotalaria burhia is a golden\u0000herb that possesses potent pharmacological activities. It is widely used as a conventional drug for\u0000the cure of various diseases, but its active constituents need to be evaluated more for future drug\u0000development and pharmacological action.\u0000\u0000\u0000\u0000There were a total of 21 research articles about the phytochemical screening of herbs,\u0000which showed the presence of different active constituents like alkaloids, tannins, flavonoids, steroids, glycosides, mucilage, gum, polyphenols, carbohydrates, terpenoids, etc., which are responsible\u0000for different pharmacological activities like antioxidant, antimicrobial, anti-inflammatory, antinociceptive, antihypertensive, antitumor, and analgesic activity.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47666242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-28DOI: 10.2174/2215083810666230428100103
Majid Mirzaei, Azizeh Farshbaf Khalili, M. Karimi, Firoozeh Akbari Asbagh, Majid Safavi, M. Yekaninejad, R. Rahimi, G. Pourmand
Date Palm Pollen (DPP) has traditionally been used to increase sexual ability and fertility. In several animal studies, the effects of this herbal medicine on testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) have been shown. This study was conducted to evaluate the effects of this drug on the serum levels of testosterone, LH, and FSH in men. In this semi-experimental study, a daily dose of 6 g dry powder of DPP in two separate doses (3 g every 12 hours) was administered orally to 30 eligible men for three months. The changes in mean serum levels of hormones were statistically evaluated after the intervention compared to the baseline. The serum concentration of the hormones was assayed through the enzyme-linked immunosorbent assay method. Data were analyzed using paired t-tests. After recruitment, among 30 participants, 24 men received the intervention and finally were analyzed. The mean (SD) age and body mass index of participants were 32.85 (0.43) years and 26.5 (0.5) kg/m2 . DPP significantly increased the serum levels of testosterone (from 5.31±0.40ng/ml to 6.88±0.71 ng/ml; p=0.019) but did not affect the serum levels of FSH (from 4.31±0.50 IU/L to 4.70±0.61 IU/L; p=0.511). It also significantly decreased the serum levels of LH (from 5.65±0.81 IU/L to 4.52±0.90 IU/L; p= 0.033). There were no reported side effects. The results indicated an increasing effect of DPP on serum testosterone and decreasing effect on serum LH. However, DPP had no significant effect on FSH serum levels.
{"title":"The Effect of Date Palm (Phoenix dactylifera L.) Pollen on the Serum Levels of Testosterone, Luteinizing, and Follicle Stimulating Hormones in Men","authors":"Majid Mirzaei, Azizeh Farshbaf Khalili, M. Karimi, Firoozeh Akbari Asbagh, Majid Safavi, M. Yekaninejad, R. Rahimi, G. Pourmand","doi":"10.2174/2215083810666230428100103","DOIUrl":"https://doi.org/10.2174/2215083810666230428100103","url":null,"abstract":"\u0000\u0000Date Palm Pollen (DPP) has traditionally been used to increase sexual\u0000ability and fertility. In several animal studies, the effects of this herbal medicine on testosterone,\u0000luteinizing hormone (LH), and follicle-stimulating hormone (FSH) have been shown.\u0000\u0000\u0000\u0000This study was conducted to evaluate the effects of this drug on the serum levels of\u0000testosterone, LH, and FSH in men.\u0000\u0000\u0000\u0000In this semi-experimental study, a daily dose of 6 g dry powder of DPP in two separate\u0000doses (3 g every 12 hours) was administered orally to 30 eligible men for three months. The\u0000changes in mean serum levels of hormones were statistically evaluated after the intervention\u0000compared to the baseline. The serum concentration of the hormones was assayed through the\u0000enzyme-linked immunosorbent assay method. Data were analyzed using paired t-tests.\u0000\u0000\u0000\u0000After recruitment, among 30 participants, 24 men received the intervention and finally\u0000were analyzed. The mean (SD) age and body mass index of participants were 32.85 (0.43) years and\u000026.5 (0.5) kg/m2\u0000. DPP significantly increased the serum levels of testosterone (from 5.31±0.40ng/ml\u0000to 6.88±0.71 ng/ml; p=0.019) but did not affect the serum levels of FSH (from 4.31±0.50 IU/L to\u00004.70±0.61 IU/L; p=0.511). It also significantly decreased the serum levels of LH (from 5.65±0.81\u0000IU/L to 4.52±0.90 IU/L; p= 0.033). There were no reported side effects.\u0000\u0000\u0000\u0000The results indicated an increasing effect of DPP on serum testosterone and decreasing\u0000effect on serum LH. However, DPP had no significant effect on FSH serum levels.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-27DOI: 10.2174/2215083810666230427113538
Amanullah, Shamim, A. Sayeed, Merajul Haque, Asim Ali Khan
Application of heat either generalised or localised is among various means employed in Unani medicine for promoting health, preventing as well as treating diseases. The concept of hotness (Ḥarārat) and application of physical heat have been in vogue during different periods of human civilization and it exists even today with certain modifications. Unani medicine offers various methods for the application of mild to moderate heat that includes Turkish bath (Ḥammām), massage (Dalk), cupping (Ḥijāma), sitz bath (Ābzan), inducing diaphoresis (Ta‘rīq), douche (Naṭūl), vapour bath (Inkibāb) and footbath (Pāshoya). Heating modalities are commonly used by Unani physicians for relieving pain and stiffness, relaxing muscles, increasing blood circulation, liquefying the sticky and adherent humours lodged in the peripheral tissues and reducing inflammation. Application of severe heat also finds a place among various modes of treatment mentioned in Unani medicine. Cauterisation (Kayy) is the mode that is employed for the stoppage of bleeding, removing putrefactive matter and destroying lesions. Unani medicine offers classical methods and instruments for heat therapy used for centuries for the promotion of health, prevention and management of diseases. Heat therapy has been found considerably effective in managing certain health problems and diseases.
{"title":"Heat Therapy: Concept, Mechanism and Application in Unani Medicine","authors":"Amanullah, Shamim, A. Sayeed, Merajul Haque, Asim Ali Khan","doi":"10.2174/2215083810666230427113538","DOIUrl":"https://doi.org/10.2174/2215083810666230427113538","url":null,"abstract":"\u0000\u0000Application of heat either generalised or localised is among various means employed in Unani medicine for promoting health, preventing as well as treating diseases. The concept of hotness (Ḥarārat) and application of physical heat have been in vogue during different periods of human civilization and it exists even today with certain modifications.\u0000\u0000\u0000\u0000Unani medicine offers various methods for the application of mild to moderate heat that includes Turkish bath (Ḥammām), massage (Dalk), cupping (Ḥijāma), sitz bath (Ābzan), inducing diaphoresis (Ta‘rīq), douche (Naṭūl), vapour bath (Inkibāb) and footbath (Pāshoya).\u0000\u0000\u0000\u0000Heating modalities are commonly used by Unani physicians for relieving pain and stiffness, relaxing muscles, increasing blood circulation, liquefying the sticky and adherent humours lodged in the peripheral tissues and reducing inflammation. Application of severe heat also finds a place among various modes of treatment mentioned in Unani medicine. Cauterisation (Kayy) is the mode that is employed for the stoppage of bleeding, removing putrefactive matter and destroying lesions.\u0000\u0000\u0000\u0000Unani medicine offers classical methods and instruments for heat therapy used for centuries for the promotion of health, prevention and management of diseases. Heat therapy has been found considerably effective in managing certain health problems and diseases.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43613817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.2174/2215083810666230419091747
Peiman Alesheikh, M. Tabatabaeichehr, H. Mortazavi, Seyed-Javad Pournaghi, J. Kasaian, Barmak Yaaghoobian, H. Akbari, Neda Kheivegi
Constipation in older adults is a common issue and is more prevalent in women. The current study aimed to assess the effectiveness of the seed of Descurainia Sophia as an herbal medicine on the severity of constipation in older women. Totally, sixty-four women aged between 50 to 70 participated in the study. The study used a randomized controlled trial to investigate the effectiveness of the seed of Descurainia Sophia on constipation. Data were collected using a constipation assessment scale and analyzed using independent samples t-test and gain score procedure. Results showed that taking a mixture of water and seeds of Descurainia Sophia significantly reduces constipation severity in older women. It was concluded that the seed of Descurainia Sophia is a safe and effective alternative for treating constipation in older women.
{"title":"The effect of the seed of Descurainia Sophia on functional constipation in Iranian women aged 50-70 years: a randomized controlled trial","authors":"Peiman Alesheikh, M. Tabatabaeichehr, H. Mortazavi, Seyed-Javad Pournaghi, J. Kasaian, Barmak Yaaghoobian, H. Akbari, Neda Kheivegi","doi":"10.2174/2215083810666230419091747","DOIUrl":"https://doi.org/10.2174/2215083810666230419091747","url":null,"abstract":"\u0000\u0000Constipation in older adults is a common issue and is more prevalent in women. The current study aimed to assess the effectiveness of the seed of Descurainia Sophia as an herbal medicine on the severity of constipation in older women.\u0000\u0000\u0000\u0000Totally, sixty-four women aged between 50 to 70 participated in the study. The study used a randomized controlled trial to investigate the effectiveness of the seed of Descurainia Sophia on constipation. Data were collected using a constipation assessment scale and analyzed using independent samples t-test and gain score procedure.\u0000\u0000\u0000\u0000Results showed that taking a mixture of water and seeds of Descurainia Sophia significantly reduces constipation severity in older women. It was concluded that the seed of Descurainia Sophia is a safe and effective alternative for treating constipation in older women.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44896316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.2174/2215083810666230418114504
Dharmendra Jain, Monika Vishwakarma, Akash Patel
Gastrointestinal (GI) and biliary disorders are the most commonly known health issues for people in the present time as a consequence of modern lifestyle, eating habits, stress, and many other conditions. The usage of traditional substances has been phased out over time, resulting in an increase in the occurrence of numerous diseases and a decrease in immunity. Therefore, in the current scenario, traditional medicine is increasingly being used to treat and manage diseases worldwide. Traditional medical systems of India, China, and Africa are the most frequently used today. Indian medicinal system includes the Ayurveda, Siddha, and Unani systems of medicine. Ayurveda is the most antique system of medicine, which relies on the usage of plant-based formulations. Herbal medicines are used nowadays by up to half of the world's population. Phytomedicines isolated from plants contain a wide variety of bioactive components that can have both negative and positive effects. Many herbal plants, such as Acacia, Aloe, Carum, Rose, Funnel, etc., are proven to be effective as phytomedicines that are effective for the cure of gastrointestinal and biliary problems. The available pharmacological therapeutic drugs often have efficacy but are associated with many adverse effects. To minimize the adverse effects, the use of phytomedicines can be the best possible alternative. In this study, a review of some of the most frequently used traditional herbal medicine isolates with their proven pharmacological activity and novel drug delivery systems for the proper delivery of isolates is presented. Moreover, currently available herbal-marketed formulations are also highlighted.
{"title":"A Review of Current Research on Traditional Medicines for the Treatment of Gastrointestinal and Biliary Disorders","authors":"Dharmendra Jain, Monika Vishwakarma, Akash Patel","doi":"10.2174/2215083810666230418114504","DOIUrl":"https://doi.org/10.2174/2215083810666230418114504","url":null,"abstract":"\u0000\u0000Gastrointestinal (GI) and biliary disorders are the most commonly known health issues for people in the present time as a consequence of modern lifestyle, eating habits, stress, and many other conditions. The usage of traditional substances has been phased out over time, resulting in an increase in the occurrence of numerous diseases and a decrease in immunity. Therefore, in the current scenario, traditional medicine is increasingly being used to treat and manage diseases worldwide. Traditional medical systems of India, China, and Africa are the most frequently used today. Indian medicinal system includes the Ayurveda, Siddha, and Unani systems of medicine. Ayurveda is the most antique system of medicine, which relies on the usage of plant-based formulations. Herbal medicines are used nowadays by up to half of the world's population. Phytomedicines isolated from plants contain a wide variety of bioactive components that can have both negative and positive effects. Many herbal plants, such as Acacia, Aloe, Carum, Rose, Funnel, etc., are proven to be effective as phytomedicines that are effective for the cure of gastrointestinal and biliary problems. The available pharmacological therapeutic drugs often have efficacy but are associated with many adverse effects. To minimize the adverse effects, the use of phytomedicines can be the best possible alternative. In this study, a review of some of the most frequently used traditional herbal medicine isolates with their proven pharmacological activity and novel drug delivery systems for the proper delivery of isolates is presented. Moreover, currently available herbal-marketed formulations are also highlighted.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45839966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-17DOI: 10.2174/2215083810666230417115041
Mamta B. Shah, Rutvi Shah, Dhyey Salot, D. Shah, Dhruvil Shah, Rajvi K Shah, Preeti D. Verma
Aesculus L. is a genus of 12 to 19 woody species, representing one of the most acclaimed examples of inter-continental incoherence of the plants native to temperate regions of the Northern Hemisphere. It is traditionally valued in Ayurveda and the Chinese system of medicine for its various species that possess antitumor, cardioprotective, anti-inflammatory and neuroprotective activities. Current studies on this genus have revealed the presence of specific saponins with a multi-spectrum of pharmacological actions and therapeutic applications. A repertoire of literature related to the biological, taxonomical, phytochemical and ethnopharmacological aspects of Aesculus genus and its uses in different indigenous populations was explored. An inventory of all the species of this genus that were found to be useful as per ethnopharmacological literature was prepared. The ethnobotany, phytochemistry and pharmacology of the individual species are outlined in this review. The extensive information cited here has adduced the likely areas where the important species of this genus can illustrate significant therapeutic intervention in the management of chronic disorders including diabetes, hypercholesterolemia and cancer. The wide range of its pharmacological actions is attributed to the distinct phytochemicals occurring in the species, especially the triterpenoidal saponins like aescin. This review amplifies the recent studies on phytochemical and pharmacological aspects, which alludes that these species have noteworthy therapeutic potential.
{"title":"A Comprehensive Review on Biological and Chemical Diversity in Aesculus L. Genus (Sapindaceae)","authors":"Mamta B. Shah, Rutvi Shah, Dhyey Salot, D. Shah, Dhruvil Shah, Rajvi K Shah, Preeti D. Verma","doi":"10.2174/2215083810666230417115041","DOIUrl":"https://doi.org/10.2174/2215083810666230417115041","url":null,"abstract":"\u0000\u0000Aesculus L. is a genus of 12 to 19 woody species, representing one of the most acclaimed examples of inter-continental incoherence of the plants native to temperate regions of the Northern Hemisphere. It is traditionally valued in Ayurveda and the Chinese system of medicine for its various species that possess antitumor, cardioprotective, anti-inflammatory and neuroprotective activities. Current studies on this genus have revealed the presence of specific saponins with a multi-spectrum of pharmacological actions and therapeutic applications. A repertoire of literature related to the biological, taxonomical, phytochemical and ethnopharmacological aspects of Aesculus genus and its uses in different indigenous populations was explored. An inventory of all the species of this genus that were found to be useful as per ethnopharmacological literature was prepared. The ethnobotany, phytochemistry and pharmacology of the individual species are outlined in this review. The extensive information cited here has adduced the likely areas where the important species of this genus can illustrate significant therapeutic intervention in the management of chronic disorders including diabetes, hypercholesterolemia and cancer. The wide range of its pharmacological actions is attributed to the distinct phytochemicals occurring in the species, especially the triterpenoidal saponins like aescin. This review amplifies the recent studies on phytochemical and pharmacological aspects, which alludes that these species have noteworthy therapeutic potential.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41428019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}