Tho Thi Thanh Nguyen, Anh Nguyen Ngoc Hoang, Thu Nguyen Anh Luu, Thuy Thi Phan Nguyen, Em Van Loi Doan, Tu Nguyen Anh Chan, H. Nguyen
Acquired vulvar lymphangioma (AVL) is a rare but important condition that requires prompt diagnosis and appropriate management to alleviate symptoms and prevent complications. AVL can erupt locally as isolated or clustered lesions which range from translucent, fluid-filled vesicles to smooth, flesh-colored papules or nodules that exude serous or crystalline liquid spontaneously or after trauma. Clinically, it can also be asymptomatic. However, symptoms are commonly accompanied by vulvar itching, burning, soreness, or unpleasant discharge. Here, we report a case series of five Vietnamese patients with AVL with diverse clinical features.
{"title":"Diverse clinical manifestations of acquired vulvar lymphangioma: a report of five cases in Vietnamese women","authors":"Tho Thi Thanh Nguyen, Anh Nguyen Ngoc Hoang, Thu Nguyen Anh Luu, Thuy Thi Phan Nguyen, Em Van Loi Doan, Tu Nguyen Anh Chan, H. Nguyen","doi":"10.4081/dr.2024.9888","DOIUrl":"https://doi.org/10.4081/dr.2024.9888","url":null,"abstract":"Acquired vulvar lymphangioma (AVL) is a rare but important condition that requires prompt diagnosis and appropriate management to alleviate symptoms and prevent complications. AVL can erupt locally as isolated or clustered lesions which range from translucent, fluid-filled vesicles to smooth, flesh-colored papules or nodules that exude serous or crystalline liquid spontaneously or after trauma. Clinically, it can also be asymptomatic. However, symptoms are commonly accompanied by vulvar itching, burning, soreness, or unpleasant discharge. Here, we report a case series of five Vietnamese patients with AVL with diverse clinical features.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140489488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carla Rosero, L. Baldeón, Valeria Alulema, Adriana Rueda, Lorena Vaca, Daniela Galarza, Cesar Prócel
Antecedents. This report presents three cases of Cutaneous tuberculosis CTB that were diagnosed at Calderon Hospital, Quito, Ecuador. The first case was Tuberculosis verrucosa cutis (TVC) in a 44-year-old man with circinated erythematous areas with ulcerated nodules and verruciform plaques from the right lower limb to the hip. The second case was Lupus Vulgaris (LV) in a 50- year-old female with one-year history of pruritic dermatosis in the left ciliary area. The third case was Scrofuloderma in a 23-year-old man with erythematous nodules that drain caseous material at neck, thorax and axillary region. Almost all laboratory tests that were available turned out to have limitations as a diagnostic tool. Conclusion. In immunocompromised and high-risk individuals with atypical lesions, it is important to correlate clinical and epidemiological characteristics with the pretest probability in order to optimize indicators and determine or exclude out the diagnosis.
{"title":"Cutaneous tuberculosis, different clinical spectrum of the same disease: the importance of pre-test probability","authors":"Carla Rosero, L. Baldeón, Valeria Alulema, Adriana Rueda, Lorena Vaca, Daniela Galarza, Cesar Prócel","doi":"10.4081/dr.2024.9770","DOIUrl":"https://doi.org/10.4081/dr.2024.9770","url":null,"abstract":"Antecedents. This report presents three cases of Cutaneous tuberculosis CTB that were diagnosed at Calderon Hospital, Quito, Ecuador. The first case was Tuberculosis verrucosa cutis (TVC) in a 44-year-old man with circinated erythematous areas with ulcerated nodules and verruciform plaques from the right lower limb to the hip. The second case was Lupus Vulgaris (LV) in a 50- year-old female with one-year history of pruritic dermatosis in the left ciliary area. The third case was Scrofuloderma in a 23-year-old man with erythematous nodules that drain caseous material at neck, thorax and axillary region. Almost all laboratory tests that were available turned out to have limitations as a diagnostic tool. Conclusion. In immunocompromised and high-risk individuals with atypical lesions, it is important to correlate clinical and epidemiological characteristics with the pretest probability in order to optimize indicators and determine or exclude out the diagnosis.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139601801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katia Sofía Palomino Aguilar, Jhonny De La Cruz Vargas, Alan Latorre Zúñiga, María del Pilar Quiñones Ávila, Laura Madeleine Urbano Rosales, E. P. Palomino Portilla
The skin covers our body and exhibits a complex structure that is adapted to the different body areas. The scalp skin is distinctive, and the histopathological alterations in its diseases also present distinctive features. We present the clinical case of a 28 year old female patient, with no significant medical history. She reported a nodular tumor on the left parietal region of the scalp, which had been present for 10 years and showed slow growth. The patient had no major discomfort other than an occasional discharge of scant whitish material upon applying pressure. Intralesional corticosteroids were administered but had no effect. Over the following year, the discomfort increased, leading to the decision to remove it. The anatomopathological study found dilated follicular hairy structures in the dermis filled with keratin and debris, surrounded by multiple sebaceous glands that flow there, all surrounded by a characteristic mesenchymal cells population, diagnosing a folliculosebaceous cystic hamartoma.
{"title":"Cystic folliculosebaceous hamartoma: an unusual histopathological entity: a case report","authors":"Katia Sofía Palomino Aguilar, Jhonny De La Cruz Vargas, Alan Latorre Zúñiga, María del Pilar Quiñones Ávila, Laura Madeleine Urbano Rosales, E. P. Palomino Portilla","doi":"10.4081/dr.2024.9825","DOIUrl":"https://doi.org/10.4081/dr.2024.9825","url":null,"abstract":"The skin covers our body and exhibits a complex structure that is adapted to the different body areas. The scalp skin is distinctive, and the histopathological alterations in its diseases also present distinctive features. We present the clinical case of a 28 year old female patient, with no significant medical history. She reported a nodular tumor on the left parietal region of the scalp, which had been present for 10 years and showed slow growth. The patient had no major discomfort other than an occasional discharge of scant whitish material upon applying pressure. Intralesional corticosteroids were administered but had no effect. Over the following year, the discomfort increased, leading to the decision to remove it. The anatomopathological study found dilated follicular hairy structures in the dermis filled with keratin and debris, surrounded by multiple sebaceous glands that flow there, all surrounded by a characteristic mesenchymal cells population, diagnosing a folliculosebaceous cystic hamartoma.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139599332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. A. Halim, S. Yusharyahya, L. Legiawati, R. Astriningrum, Sondang P. Sirait
Porokeratosis is a group of chronic dermatoses characterized by the presence of cornoid lamellae. Disseminated superficial actinic porokeratosis (DSAP) is a common subtype, presenting as multiple small annular scaly lesions primarily in sun-exposed areas. While previous studies have documented DSAP in prostate cancer patients, the association with androgen deprivation therapy (ADT) has not been reported. In this report, we describe an elderly patient with advanced prostate cancer, who developed DSAP subsequent to undergoing ADT. We present the clinical, dermoscopic, and histopathological evaluations, and discuss the potential role of ADT in the pathogenesis of DSAP.
{"title":"Disseminated superficial actinic porokeratosis in an elderly patient undergoing androgen deprivation therapy for advanced prostate cancer: exploring the potential association","authors":"P. A. Halim, S. Yusharyahya, L. Legiawati, R. Astriningrum, Sondang P. Sirait","doi":"10.4081/dr.2024.9850","DOIUrl":"https://doi.org/10.4081/dr.2024.9850","url":null,"abstract":"Porokeratosis is a group of chronic dermatoses characterized by the presence of cornoid lamellae. Disseminated superficial actinic porokeratosis (DSAP) is a common subtype, presenting as multiple small annular scaly lesions primarily in sun-exposed areas. While previous studies have documented DSAP in prostate cancer patients, the association with androgen deprivation therapy (ADT) has not been reported. In this report, we describe an elderly patient with advanced prostate cancer, who developed DSAP subsequent to undergoing ADT. We present the clinical, dermoscopic, and histopathological evaluations, and discuss the potential role of ADT in the pathogenesis of DSAP.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139600323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The philosopher of science, Telmo Pievani, in his beautiful and passionate presentation on 30 September 2023, at the conclusion of the 60th National Congress of the Italian Association of Hospital Dermatologists (ADOI) held in Vicenza, reminded us with simple words and concrete examples of the devastating impact of human behavior on the environment and biodiversity, highlighting the growing deterioration of the delicate natural balances that preserve terrestrial ecosystems and with them life on our planet [...]
{"title":"Choosing Wisely Italy, and the role of doctors in containing the climate emergency","authors":"Antonio Bonaldi","doi":"10.4081/dr.2023.9881","DOIUrl":"https://doi.org/10.4081/dr.2023.9881","url":null,"abstract":"The philosopher of science, Telmo Pievani, in his beautiful and passionate presentation on 30 September 2023, at the conclusion of the 60th National Congress of the Italian Association of Hospital Dermatologists (ADOI) held in Vicenza, reminded us with simple words and concrete examples of the devastating impact of human behavior on the environment and biodiversity, highlighting the growing deterioration of the delicate natural balances that preserve terrestrial ecosystems and with them life on our planet [...]","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138958968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The nose is a vital organ and an important aesthetic unit, being placed in the middle of the face. It is also one of the most frequently site involved by skin cancer, and surgical reconstruction can be sometimes challenging. We present two cases of full thickness nasal ala defect, managed with turnover flap with and without earlobe cartilage graft.
{"title":"Turnover flap variations in the reconstruction of full-thickness nasal ala defects","authors":"Paola Monari, Alessandra Petruzzellis, Sara Mezzana, Simone Soglia, Pier Giacomo Calzavara-Pinton, Luca Bianchi, Giulio Gualdi","doi":"10.4081/dr.2023.9848","DOIUrl":"https://doi.org/10.4081/dr.2023.9848","url":null,"abstract":"The nose is a vital organ and an important aesthetic unit, being placed in the middle of the face. It is also one of the most frequently site involved by skin cancer, and surgical reconstruction can be sometimes challenging. We present two cases of full thickness nasal ala defect, managed with turnover flap with and without earlobe cartilage graft.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136261593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danny Surya, Melani Marissa, Windy Keumala Budianti, Rahadi Rihatmadja, Inge Ade Krisanti, Dewi Friska, Sandra Widaty
Background. Hand eczema (HE) commonly occurs in healthcare services, especially during COVID-19 pandemic era. Vitamin D shows various effects on skin inflammation. This study aims to analyze the correlation between HE severity and vitamin D levels as measured by serum 25(OH)D in healthcare workers. Method. This is an analytic descriptive study with a cross-sectional design conducted in Indonesia between September-October 2022. HE severity was assessed using Hand Eczema Severity Index (HECSI). Results. Among 44 healthcare workers with HE, 29 people had mild HE, 11 had moderate HE, and 4 had severe HE. The mean serum 25(OH)D level in subjects with mild, moderate, and severe HE was 17.85 ng/mL, 16.45 ng/mL, and 17.87 ng/mL, respectively, which belonged to vitamin D deficiency category. There was no statistically significant correlation between serum 25(OH)D levels and HE severity (r = -0.056; p = 0.359). Conclusions. There was no significant difference in serum 25(OH)D levels between subjects with mild, moderate, and severe HE. Serum 25(OH)D level was not inversely correlated with HE severity.
{"title":"Correlation between serum 25(OH)D levels with severity of work-related hand eczema among healthcare workers: a cross-sectional study","authors":"Danny Surya, Melani Marissa, Windy Keumala Budianti, Rahadi Rihatmadja, Inge Ade Krisanti, Dewi Friska, Sandra Widaty","doi":"10.4081/dr.2023.9861","DOIUrl":"https://doi.org/10.4081/dr.2023.9861","url":null,"abstract":"Background. Hand eczema (HE) commonly occurs in healthcare services, especially during COVID-19 pandemic era. Vitamin D shows various effects on skin inflammation. This study aims to analyze the correlation between HE severity and vitamin D levels as measured by serum 25(OH)D in healthcare workers. Method. This is an analytic descriptive study with a cross-sectional design conducted in Indonesia between September-October 2022. HE severity was assessed using Hand Eczema Severity Index (HECSI). Results. Among 44 healthcare workers with HE, 29 people had mild HE, 11 had moderate HE, and 4 had severe HE. The mean serum 25(OH)D level in subjects with mild, moderate, and severe HE was 17.85 ng/mL, 16.45 ng/mL, and 17.87 ng/mL, respectively, which belonged to vitamin D deficiency category. There was no statistically significant correlation between serum 25(OH)D levels and HE severity (r = -0.056; p = 0.359). Conclusions. There was no significant difference in serum 25(OH)D levels between subjects with mild, moderate, and severe HE. Serum 25(OH)D level was not inversely correlated with HE severity.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paolo Iacovelli, Alessia Pacifico, Maria Mariano, Diego Orsini, Andrea D'Arino, Flavia Pigliacelli
Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma, clinically characterized by erythematous-scaly patches and erythematous-violaceous nodules. Phototherapy plays an important role in MF, currently used as first line treatment in the early stages. The aim of this study is to analyze and review the different options of phototherapy on cutaneous lymphoma.
{"title":"Phototherapy and mycosis fungoides: what’s new?","authors":"Paolo Iacovelli, Alessia Pacifico, Maria Mariano, Diego Orsini, Andrea D'Arino, Flavia Pigliacelli","doi":"10.4081/dr.2023.9830","DOIUrl":"https://doi.org/10.4081/dr.2023.9830","url":null,"abstract":"Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma, clinically characterized by erythematous-scaly patches and erythematous-violaceous nodules. Phototherapy plays an important role in MF, currently used as first line treatment in the early stages. The aim of this study is to analyze and review the different options of phototherapy on cutaneous lymphoma.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135995023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michela Curzio, Vittorio Macchini, Giovanni Di Lella, Antonio Massaro, Giulio Sonego
We present the case of a 55 years old male patient who came to our attention because of a basal cell carcinoma of the right retroauricolar area, near the mastoid-auricle border. The tumour had a size of about 1,5 cm. Repairing retroauricolar surgical defects may be actually very challenging, firstly because an incorrect reconstruction may result in severe deformities which are extremely hard to conceal; so we decided to employ the "jigsaw puzzle" advancement flap, a versatile flap, firstly successfully used in the reconstruction of a nasal ala defect.
{"title":"Reconstruction of retroauricolar surgical defect using the \"Jigsaw puzzle\" advancement flap","authors":"Michela Curzio, Vittorio Macchini, Giovanni Di Lella, Antonio Massaro, Giulio Sonego","doi":"10.4081/dr.2023.9724","DOIUrl":"https://doi.org/10.4081/dr.2023.9724","url":null,"abstract":"We present the case of a 55 years old male patient who came to our attention because of a basal cell carcinoma of the right retroauricolar area, near the mastoid-auricle border. The tumour had a size of about 1,5 cm. Repairing retroauricolar surgical defects may be actually very challenging, firstly because an incorrect reconstruction may result in severe deformities which are extremely hard to conceal; so we decided to employ the \"jigsaw puzzle\" advancement flap, a versatile flap, firstly successfully used in the reconstruction of a nasal ala defect.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135996078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alice Verdelli, Daniela Massi, Vincenza Maio, Gabriele Cavazza, Alberto Corrà, Elena Biancamaria Mariotti, Lavinia Quintarelli, Valentina Ruffo Di Calabria, Cristina Aimo, Emiliano Antiga, Marzia Caproni
Lupus erythematosus tumidus (LET) is a subset of cutaneous lupus erythematosus that generally presents with urticaria-like papules and plaques located on sun-exposed areas. Systemic treatment with antimalarials, especially hydroxychloroquine (HCQ), is the first-line systemic therapy for LET. Even if these drugs have a safe profile, side effects such as retinal toxicity, maculopapular rash, gastrointestinal upset, hemolytic anemia and blue-gray discoloration of the skin or the mucous membranes, have been rarely reported in the literature. Herein, we describe a rare case of a 46-year-old smoking woman with LET who developed a generalized myopathy after HCQ treatment.
{"title":"Hydroxychloroquine-induced generalized myopathy in a patient with lupus tumidus: a case report","authors":"Alice Verdelli, Daniela Massi, Vincenza Maio, Gabriele Cavazza, Alberto Corrà, Elena Biancamaria Mariotti, Lavinia Quintarelli, Valentina Ruffo Di Calabria, Cristina Aimo, Emiliano Antiga, Marzia Caproni","doi":"10.4081/dr.2023.9771","DOIUrl":"https://doi.org/10.4081/dr.2023.9771","url":null,"abstract":"Lupus erythematosus tumidus (LET) is a subset of cutaneous lupus erythematosus that generally presents with urticaria-like papules and plaques located on sun-exposed areas. Systemic treatment with antimalarials, especially hydroxychloroquine (HCQ), is the first-line systemic therapy for LET. Even if these drugs have a safe profile, side effects such as retinal toxicity, maculopapular rash, gastrointestinal upset, hemolytic anemia and blue-gray discoloration of the skin or the mucous membranes, have been rarely reported in the literature. Herein, we describe a rare case of a 46-year-old smoking woman with LET who developed a generalized myopathy after HCQ treatment.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135993245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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