Dermatology Reports最新文献

Dear Editor, Loxoscelism, resulting from bites by Loxosceles spiders - particularly Loxosceles reclusa - is characterized by necrotic skin lesions and, in severe cases, systemic symptoms such as hemolysis, acute renal failure, and disseminated intravascular coagulation (DIC). [...].

The use of teledermatology has increased significantly in recent years. The objective of this study was to determine Canadian dermatologists' and dermatology residents' perspectives on teledermatology. An online survey was created to determine participants' teledermatology practice patterns and their perception of the challenges, education, training, and research in teledermatology. The survey was distributed through the Canadian Dermatology Association and by administrative staff at Canadian Dermatology departments. A total of 33 respondents completed the survey: 66.7% of respondents started using teledermatology during the COVID-19 pandemic, and 93.8% reported that teledermatology accounted for 0-25% of their practice. Convenience, access, and safety were identified as the primary advantages of teledermatology. Teledermatology was mainly utilized for medication monitoring or refills and to assess, manage, or follow up on dermatitis, other chronic inflammatory conditions, and pre-diagnosed dermatologic conditions. Poor photo quality (32.3%) and the inability to conduct physical examinations or accurately diagnose conditions (74.2%) were reported as significant challenges. Respondents recommended education on the medicolegal considerations of teledermatology and research on how teledermatology compares to in-person consultations. Overall, teledermatology improves convenience, access to care, and safety for both patients and healthcare professionals. However, addressing challenges related to physical examinations, accurate diagnoses, and photo quality is essential for optimal care delivery.

Bier's spots are rare angiospastic macules often associated with physiologic vasoconstriction. This case report describes a 35-year-old man with chronic myeloid leukemia (CML) treated with nilotinib who developed Bier's spots, a previously unreported adverse effect of the drug. The patient presented with asymptomatic hypopigmented macules on the hands and legs that appeared during venous stasis and resolved with elevation. This case emphasizes the need to recognize potential vascular side effects of tyrosine kinase inhibitors (TKIs) and highlights Bier's spots as a benign but remarkable manifestation in patients undergoing nilotinib therapy.

A 19-year-old female with severe hidradenitis suppurativa (HS), treated with adalimumab for 10 months, developed facial erysipelas following an episode of pharyngitis. The infection presented with fever, severe cough, and a rapidly progressing erythematous plaque with edema on the left cheek, forehead, and periocular region. Laboratory tests confirmed a streptococcal infection. Due to allergies and intolerance to first-line antibiotics, azithromycin was administered, leading to complete resolution. This case highlights the increased risk of severe infections in immunosuppressed patients and underscores the importance of careful antibiotic selection and close monitoring for infections in patients receiving TNF-α inhibitors.

Unusual skin infection localization represents a challenge to physicians regarding presentation and mode of acquisition, which may influence the diagnosis. At the same time, the administration of incorrect drugs due to a misdiagnosis might have a negative impact on the disease course. This article presents two cases detailing the unusual presentation of larva migrans and scabies mite infection in two Italian patients, highlighting the importance of clinical vigilance and comprehensive evaluation of patients. These cases suggest how an accurate diagnosis requires a high index of suspicion and appropriate diagnostic tools, such as dermoscopy, for the prompt recognition of skin infections and the consequent optimal patient outcome.

Petrified ear is a rare clinical entity characterized by the progressive hardening of normal, flexible auricular cartilage, leading to partial or complete auricular stiffness. In many cases, it provides a valuable clinical clue that allows the clinician to detect endocrinopathies (particularly Addison's disease) in a patient who has not received a diagnosis. We present the first documented case of petrified ears, which resulted in the diagnosis of both secondary hypoadrenalism and growth hormone deficiency (GHD). Additionally, we review the relevant literature. Petrified ear syndrome is probably an underreported clinical manifestation of other systemic disorders. It may, at times, serve as a valuable and simple clinical clue to suspect underlying endocrinopathies even in the absence of typical features.

Urticaria is a prevalent inflammatory dermatological condition with a global estimated lifetime prevalence of up to 20%. Yellow urticaria is not a distinct medical condition; rather, it refers to the manifestation of yellow-colored wheals that appear in certain individuals with elevated serum bilirubin levels. This excess bilirubin accumulates in various tissues, including the conjunctiva and skin. The occurrence of yellow urticaria is notably rare and uncommon. In this report, we present a case of yellow-colored urticaria in a patient diagnosed with obstructive biliary stones, complemented by a concise review of previously documented cases in the literature.

This report presents the case of a 22-year-old male with recurrent genital ulcers, oral aphthae, and gastrointestinal ulcerations initially diagnosed as Crohn's disease by gastroenterologists. Despite overlapping clinical and histological features between Crohn's disease and intestinal Behçet's disease, a dermatological consultation raised suspicion for Behçet's, leading to a revised diagnosis. This case highlights the crucial role of dermatologists in preventing misdiagnosis and ensuring effective treatments for complex inflammatory conditions.

Pityriasis rubra pilaris is a rare idiopathic papulosquamous disorder that significantly impacts quality of life and is often refractory to conventional therapies. This study presents a case of successful treatment with an abrocitinib JAK1 inhibitor after several conventional and biologic therapies failed.

We describe the second case of infection by Emergomyces pasteurianus in Italy. The patient presented ulcerated nodular lesions primarily in the forehead, beneath the orbital and nasal areas, but also in the neck and fingers in the early stages. Treatment involved amphotericin B, followed by long-term itraconazole, which resulted in complete clinical resolution. A review of the literature is also included.