Karan Rajalingam, Phillip Johansen, Nicole Levin, Jerry Qi, Oge Marques
Psoriasis is a chronic skin disorder, and patients encounter high physical and psychosocial burdens. Social media forums feature extensive patient-generated comments. We hypothesized that analyzing patient-posted comments using natural language processing would provide insights into patient engagements, sentiments, concerns, and support, which are vital for the holistic management of psoriasis. We collected 32,000 active user comments posted on Reddit-forum. We applied Latent Dirichlet Allocation to categorize posts into popular topics and employed spectral clustering to establish cohesive themes and word representation frequency within these topics. We sorted posts into 29 significant topics of discussion and categorized them into four categories: management (37.48%), emotion (21.57%), presentation (19.79%), and others (3.57%). The frequent posts on management were diet (7.23%), biologics (6.95%), and adverse-effects (3.88%). Emotion category comprised negative sentiments (11.02%), encouragement (5.49%), and gratitude (5.06%). Presentation topic included a discussion of scalp (5.69%), flare-timing (3.63%), and arthritis (2.64%). Others comprised differential-diagnosis (5.01%), leaky gut (4.12%), and referrals (3.70%). This study identified patients’ experiences and perspectives associated with psoriasis, which should be considered to tailor support systems to improve their quality of life.
{"title":"Natural language processing of online support group postings reveals patient perspectives on strategies for managing psoriasis","authors":"Karan Rajalingam, Phillip Johansen, Nicole Levin, Jerry Qi, Oge Marques","doi":"10.4081/dr.2023.9824","DOIUrl":"https://doi.org/10.4081/dr.2023.9824","url":null,"abstract":"Psoriasis is a chronic skin disorder, and patients encounter high physical and psychosocial burdens. Social media forums feature extensive patient-generated comments. We hypothesized that analyzing patient-posted comments using natural language processing would provide insights into patient engagements, sentiments, concerns, and support, which are vital for the holistic management of psoriasis. We collected 32,000 active user comments posted on Reddit-forum. We applied Latent Dirichlet Allocation to categorize posts into popular topics and employed spectral clustering to establish cohesive themes and word representation frequency within these topics. We sorted posts into 29 significant topics of discussion and categorized them into four categories: management (37.48%), emotion (21.57%), presentation (19.79%), and others (3.57%). The frequent posts on management were diet (7.23%), biologics (6.95%), and adverse-effects (3.88%). Emotion category comprised negative sentiments (11.02%), encouragement (5.49%), and gratitude (5.06%). Presentation topic included a discussion of scalp (5.69%), flare-timing (3.63%), and arthritis (2.64%). Others comprised differential-diagnosis (5.01%), leaky gut (4.12%), and referrals (3.70%). This study identified patients’ experiences and perspectives associated with psoriasis, which should be considered to tailor support systems to improve their quality of life.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135981309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Del Rio-Martinez, Patricio Mendoza-Galvez, Victoria Holguin-Montaño, Marcela Santos-Flores
Hyaluronic acid filler, a temporary injectable used for rejuvenating facial treatments, has gained significant popularity over the years due to its nonsurgical approach. While these procedures are generally safe, there are certain complications associated with their application. These complications can be categorized into early-, delayed-, and late-onset reactions. In this case report, we present a 55-year-old female who experienced a delayed hypersensitivity reaction following the application of hyaluronic acid filler, resulting in generalized facial edema.
{"title":"Delayed hypersensitivity reaction of hyaluronic acid filler (VCY-20)","authors":"Christopher Del Rio-Martinez, Patricio Mendoza-Galvez, Victoria Holguin-Montaño, Marcela Santos-Flores","doi":"10.4081/dr.2023.9800","DOIUrl":"https://doi.org/10.4081/dr.2023.9800","url":null,"abstract":"Hyaluronic acid filler, a temporary injectable used for rejuvenating facial treatments, has gained significant popularity over the years due to its nonsurgical approach. While these procedures are generally safe, there are certain complications associated with their application. These complications can be categorized into early-, delayed-, and late-onset reactions. In this case report, we present a 55-year-old female who experienced a delayed hypersensitivity reaction following the application of hyaluronic acid filler, resulting in generalized facial edema.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135979418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Ho Kwak, Chan Ho Na, Bong Seok Shin, Min Sung Kim, Hoon Choi
Dear Editor, Pyoderma gangrenosum(PG) is a rare neutrophilic dermatosis that causes the development of painful ulcers on the skin, initially starting with nodules or abscesses, and quickly progressing at the peripheral regions into ulcers.1 The exact cause is not yet known, and 20-30% of patients are said to experience a pathergy phenomenon in which lesions occur in the sites of previous trauma.2 In addition, pyoderma gangrenosum is accompanied by systemic diseases, such as Crohn's disease or inflammatory colitis, rheumatoid arthritis, and hyperthyroidism.3 Although numerous reports indicate that pyoderma gangrenosum is associated with systemic diseases,4 case reports on the association of pyoderma gangrenosum with skin diseases, especially blistering disorders, are very rare. [...]
{"title":"Pyoderma gangrenosum developed from aggravated pemphigus foliaceous after dog bite","authors":"Jun Ho Kwak, Chan Ho Na, Bong Seok Shin, Min Sung Kim, Hoon Choi","doi":"10.4081/dr.2023.9633","DOIUrl":"https://doi.org/10.4081/dr.2023.9633","url":null,"abstract":"Dear Editor, Pyoderma gangrenosum(PG) is a rare neutrophilic dermatosis that causes the development of painful ulcers on the skin, initially starting with nodules or abscesses, and quickly progressing at the peripheral regions into ulcers.1 The exact cause is not yet known, and 20-30% of patients are said to experience a pathergy phenomenon in which lesions occur in the sites of previous trauma.2 In addition, pyoderma gangrenosum is accompanied by systemic diseases, such as Crohn's disease or inflammatory colitis, rheumatoid arthritis, and hyperthyroidism.3 Although numerous reports indicate that pyoderma gangrenosum is associated with systemic diseases,4 case reports on the association of pyoderma gangrenosum with skin diseases, especially blistering disorders, are very rare. [...]","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135979444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dario Graceffa, Martina Silvestri, Norma Cameli, Viviana Lora, Antonio Cristaudo, Claudio Bonifati, Carlo Cota, Pierluigi Saraceni
Dear Editor, Hidradenitis suppurativa (HS) or acne inversus, is a chronic inflammatory cutaneous disease with a significant negative impact on the patient's quality of life, from a psychological, social and occupational point of view. The disease mainly affects the female sex and occurs between puberty and 40 years of age. It is estimated that in Europe the prevalence of the disease in the general population is 1%.1 Recent studies have shown a high incidence of inflammatory arthritis, in particular spondyloarthritis, in patients with HS.2 In this report, we present 18 cases of patients with hidradenitis suppurativa, visited at the San Gallicano Dermatological Institute, who presented joint symptoms. [...]
{"title":"Can hydradenitis suppurativa be associated with inflammatory joint involvement? Report of a case series and review of the literature.","authors":"Dario Graceffa, Martina Silvestri, Norma Cameli, Viviana Lora, Antonio Cristaudo, Claudio Bonifati, Carlo Cota, Pierluigi Saraceni","doi":"10.4081/dr.2023.9815","DOIUrl":"https://doi.org/10.4081/dr.2023.9815","url":null,"abstract":"Dear Editor, Hidradenitis suppurativa (HS) or acne inversus, is a chronic inflammatory cutaneous disease with a significant negative impact on the patient's quality of life, from a psychological, social and occupational point of view. The disease mainly affects the female sex and occurs between puberty and 40 years of age. It is estimated that in Europe the prevalence of the disease in the general population is 1%.1 Recent studies have shown a high incidence of inflammatory arthritis, in particular spondyloarthritis, in patients with HS.2 In this report, we present 18 cases of patients with hidradenitis suppurativa, visited at the San Gallicano Dermatological Institute, who presented joint symptoms. [...]","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"365 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135980972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11eCollection Date: 2024-09-02DOI: 10.4081/dr.2024.9815
Dario Graceffa, Martina Silvestri, Norma Cameli, Viviana Lora, Antonio Cristaudo, Claudio Bonifati, Carlo Cota, Pier Luigi Saraceni
{"title":"Can hydradenitis suppurativa be associated with inflammatory joint involvement? Report of a case series and review of the literature.","authors":"Dario Graceffa, Martina Silvestri, Norma Cameli, Viviana Lora, Antonio Cristaudo, Claudio Bonifati, Carlo Cota, Pier Luigi Saraceni","doi":"10.4081/dr.2024.9815","DOIUrl":"10.4081/dr.2024.9815","url":null,"abstract":"","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"16 3","pages":"9815"},"PeriodicalIF":2.3,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Buffon, Michele Parietti, Andrea Carugno, Elisa Robustelli Test, Angelo Valerio Marzano, Paolo Sena, Pamela Vezzoli
Linear immunoglobulin (Ig) A disease (LAD) is a rare autoimmune blistering dermatosis caused by linear deposition of IgA1 along the dermoepidermal junction of skin and mucosae. It can affect both children and adults. Although idiopathic in most cases, it can also be associated with infections, malignancies, or drug administration. Among medications, antibiotics are most commonly responsible, particularly vancomycin. We report the case of a 51-year-old female patient who developed mucocutaneous LAD after oral metronidazole administration, which was confirmed by histopathological examination and direct immunofluorescence of one of the bullous lesions. Lesions rapidly cleared after metronidazole discontinuation and a short course of oral methylprednisolone and dapsone. To our knowledge, this is the third reported case of metronidazole-induced LAD, and the first in which metronidazole was not administered in combination with other antibiotics such as ceftriaxone.
{"title":"Metronidazole-induced linear immunoglobulin A disease in a patient suffering from ulcerative colitis: a case report and focused review of the literature","authors":"Stefano Buffon, Michele Parietti, Andrea Carugno, Elisa Robustelli Test, Angelo Valerio Marzano, Paolo Sena, Pamela Vezzoli","doi":"10.4081/dr.2023.9831","DOIUrl":"https://doi.org/10.4081/dr.2023.9831","url":null,"abstract":"Linear immunoglobulin (Ig) A disease (LAD) is a rare autoimmune blistering dermatosis caused by linear deposition of IgA1 along the dermoepidermal junction of skin and mucosae. It can affect both children and adults. Although idiopathic in most cases, it can also be associated with infections, malignancies, or drug administration. Among medications, antibiotics are most commonly responsible, particularly vancomycin. We report the case of a 51-year-old female patient who developed mucocutaneous LAD after oral metronidazole administration, which was confirmed by histopathological examination and direct immunofluorescence of one of the bullous lesions. Lesions rapidly cleared after metronidazole discontinuation and a short course of oral methylprednisolone and dapsone. To our knowledge, this is the third reported case of metronidazole-induced LAD, and the first in which metronidazole was not administered in combination with other antibiotics such as ceftriaxone.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136283194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29eCollection Date: 2024-09-02DOI: 10.4081/dr.2024.9793
Vittoria Cioppa, Pietro Rubegni, Ernesto De Piano
{"title":"Delayed breast cellulitis post nipple-sparing mastectomy surgery.","authors":"Vittoria Cioppa, Pietro Rubegni, Ernesto De Piano","doi":"10.4081/dr.2024.9793","DOIUrl":"10.4081/dr.2024.9793","url":null,"abstract":"","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"16 3","pages":"9793"},"PeriodicalIF":2.3,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ernesto De Piano, Vittoria Cioppa, Valentina Ongaro, Filomena Russo, Pietro Rubegni, Clelia Miracco
Not available
不可用
{"title":"Definitive histology control after Mohs micrographic surgery: pleonastic or not?","authors":"Ernesto De Piano, Vittoria Cioppa, Valentina Ongaro, Filomena Russo, Pietro Rubegni, Clelia Miracco","doi":"10.4081/dr.2023.9827","DOIUrl":"https://doi.org/10.4081/dr.2023.9827","url":null,"abstract":"Not available","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136283375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delayed breast cellulitis post nipple-sparing mastectomy surgery","authors":"Vittoria Cioppa, Pietro Rubegni, E. De Piano","doi":"10.4081/dr.2023.9793","DOIUrl":"https://doi.org/10.4081/dr.2023.9793","url":null,"abstract":"Not available","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42101161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29eCollection Date: 2024-09-02DOI: 10.4081/dr.2024.9827
Ernesto De Piano, Vittoria Cioppa, Valentina Ongaro, Filomena Russo, Pietro Rubegni, Clelia Miracco
{"title":"Definitive histology control after Mohs micrographic surgery: pleonastic or not?","authors":"Ernesto De Piano, Vittoria Cioppa, Valentina Ongaro, Filomena Russo, Pietro Rubegni, Clelia Miracco","doi":"10.4081/dr.2024.9827","DOIUrl":"10.4081/dr.2024.9827","url":null,"abstract":"","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":"16 3","pages":"9827"},"PeriodicalIF":2.3,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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