Extensive research has been published on atopic dermatitis (AD), a prevalent skin condition amongst pediatricians. To assess the pediatric representation in the most cited literature on AD, using bibliometric analysis. Web of Science citation indexing database was used to identify publications with "atopic" and "dermatitis" or "eczema" in their title. Results were ranked by their Annual citation(Ac) and refined to the 100 topmost cited articles in the non-refined pediatric category and the top five journals in the categories of general medicine, dermatology, and pediatrics, by impact factor. 28,360 publications were retrieved. The metrics were significantly higher in dermatology, compared to pediatric and general categories [(RTC = 0.899, p < .001), (RAC = 0.795, p < .001), (Rusage count = 0.639, p < .001)] and [(RTC = 0.417, p < .001), (RAC = 0.392, p < .001), (Rusage count = 0.279, p < .001)]. This analysis is the first to highlight the underrepresentation of AD publications in the pediatric literature, which might impact the clinicians' and patients' level of care and AD annual societal expenditure.
特应性皮炎（AD）是儿科医生中普遍存在的一种皮肤病，有关特应性皮炎的研究成果已广泛发表。通过文献计量学分析，评估儿科在特应性皮炎被引用最多的文献中的代表性。使用 Web of Science 引文索引数据库识别标题中包含 "特应性"、"皮炎 "或 "湿疹 "的出版物。研究结果按年度引文（Ac）进行排序，并按影响因子细化为非细化儿科类别中被引用次数最多的 100 篇文章，以及普通医学类、皮肤病学类和儿科类中被引用次数最多的 5 种期刊。共检索到 28,360 篇出版物。皮肤病学的指标明显高于儿科和普通类[(RTC = 0.899, p < .001), (RAC = 0.795, p < .001), (Rusage count = 0.639, p < .001)] 和[(RTC = 0.417, p < .001), (RAC = 0.392, p < .001), (Rusage count = 0.279, p < .001)]。该分析首次强调了儿科文献中有关注意力缺失症的论文数量不足，这可能会影响临床医生和患者的护理水平以及注意力缺失症的年度社会支出。
{"title":"Underrepresentation of atopic dermatitis publications in pediatric journals: a bibliometric analysis","authors":"Barak Zlakishvili, Sarah Weissmann, Amir Horev","doi":"10.4081/dr.2024.9932","DOIUrl":"https://doi.org/10.4081/dr.2024.9932","url":null,"abstract":"Extensive research has been published on atopic dermatitis (AD), a prevalent skin condition amongst pediatricians. To assess the pediatric representation in the most cited literature on AD, using bibliometric analysis. Web of Science citation indexing database was used to identify publications with \"atopic\" and \"dermatitis\" or \"eczema\" in their title. Results were ranked by their Annual citation(Ac) and refined to the 100 topmost cited articles in the non-refined pediatric category and the top five journals in the categories of general medicine, dermatology, and pediatrics, by impact factor. 28,360 publications were retrieved. The metrics were significantly higher in dermatology, compared to pediatric and general categories [(RTC = 0.899, p < .001), (RAC = 0.795, p < .001), (Rusage count = 0.639, p < .001)] and [(RTC = 0.417, p < .001), (RAC = 0.392, p < .001), (Rusage count = 0.279, p < .001)]. This analysis is the first to highlight the underrepresentation of AD publications in the pediatric literature, which might impact the clinicians' and patients' level of care and AD annual societal expenditure.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140711961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Florine Le Lay, Marianna Deparis, Sylvie Fraitag, Anne Dompmartin
Ataxia telangiectasia (AT) is a rare autosomal recessive primary immunodeficiency disorder (PID) resulting from a mutation in the ATM gene, which is involved in DNA repair. We describe the case of a young girl with cutaneous granulomas that developed after childhood vaccinations. Immunohistochemistry revealed granulomas induced by the rubella virus vaccine. This finding raises the question of live rubella vaccine strains safety in immunocompromised children.
共济失调毛细血管扩张症（AT）是一种罕见的常染色体隐性原发性免疫缺陷病（PID），由参与 DNA 修复的 ATM 基因突变引起。我们描述了一个在儿童接种疫苗后出现皮肤肉芽肿的年轻女孩的病例。免疫组化显示，肉芽肿由风疹病毒疫苗诱发。这一发现提出了免疫力低下儿童接种风疹活疫苗株的安全性问题。
{"title":"Rubella virus vaccine-induced granulomas: a case in children with ataxia-telangiectasia","authors":"Florine Le Lay, Marianna Deparis, Sylvie Fraitag, Anne Dompmartin","doi":"10.4081/dr.2024.9864","DOIUrl":"https://doi.org/10.4081/dr.2024.9864","url":null,"abstract":"Ataxia telangiectasia (AT) is a rare autosomal recessive primary immunodeficiency disorder (PID) resulting from a mutation in the ATM gene, which is involved in DNA repair. We describe the case of a young girl with cutaneous granulomas that developed after childhood vaccinations. Immunohistochemistry revealed granulomas induced by the rubella virus vaccine. This finding raises the question of live rubella vaccine strains safety in immunocompromised children.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140715742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 74-year-old male presented to the dermatology department with tumor formation located in the left auricle area, measuring 2 cm in size. The tumor exhibited surface erosions and periphereal erythema. Additionally, in the right lower eyelid and temporal regions, clinically suspected lesions for squamous cell carcinomas were noted. [...]
{"title":"Modified advancement transposition flap for squamous cell carcinoma with periauricular location","authors":"Georgi Tchernev, S. Kordeva","doi":"10.4081/dr.2024.9977","DOIUrl":"https://doi.org/10.4081/dr.2024.9977","url":null,"abstract":"A 74-year-old male presented to the dermatology department with tumor formation located in the left auricle area, measuring 2 cm in size. The tumor exhibited surface erosions and periphereal erythema. Additionally, in the right lower eyelid and temporal regions, clinically suspected lesions for squamous cell carcinomas were noted. [...]","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140729113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The skin moisturizing function decline with age, leading to skin dryness in approximately 40% of the olderly. Various lifestyle habits may affect the skin moisturizing function, however it is not clear which ones are particularly relevant. A cross-sectional study was conducted between September and December 2023, involving individuals aged 65 years and older. Self-administered questionnaire were employed to collect information on lifestyle habits. Stratum corneum hydration (SC hydration), as an indicator of skin hydration, was measured and analyzed using multiple regression. A total of 124 individuals participated in the study, with a mean age of 83.6 years. Daily use of moisturizer (p=0.024) and activity level (p=0.002) demonstrated significant associations with increased SC hydration. Although not statistically significant, smoking exhibited a trend towards decreased SC hydration (p=0.173). The findings of this study suggest that, among various lifestyle habits, exercise and daily moisturizing contribute to enhanced SC hydration. These results suggest that lifestyle modifications may improve the skin moisturizing function of olderly.
{"title":"Association between lifestyle and skin moisturizing function in community-dwelling older adults","authors":"Ryo Oizumi, Rie Shibata","doi":"10.4081/dr.2024.9964","DOIUrl":"https://doi.org/10.4081/dr.2024.9964","url":null,"abstract":"The skin moisturizing function decline with age, leading to skin dryness in approximately 40% of the olderly. Various lifestyle habits may affect the skin moisturizing function, however it is not clear which ones are particularly relevant. A cross-sectional study was conducted between September and December 2023, involving individuals aged 65 years and older. Self-administered questionnaire were employed to collect information on lifestyle habits. Stratum corneum hydration (SC hydration), as an indicator of skin hydration, was measured and analyzed using multiple regression. A total of 124 individuals participated in the study, with a mean age of 83.6 years. Daily use of moisturizer (p=0.024) and activity level (p=0.002) demonstrated significant associations with increased SC hydration. Although not statistically significant, smoking exhibited a trend towards decreased SC hydration (p=0.173). The findings of this study suggest that, among various lifestyle habits, exercise and daily moisturizing contribute to enhanced SC hydration. These results suggest that lifestyle modifications may improve the skin moisturizing function of olderly.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140736373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni Sarracco, Fabio Rinaldi, Francesco Cusano
Cutaneous squamous cell carcinoma (cSCC) is a nonmelanoma skin cancer whose lesions mostly arise on lightexposed sites. Patients with compromised immunity, Fitzpatrick I or II skin phototype, and previous burn scars or radiations are more at risk of developing it. The treatment of choice for cSCC is surgery; however nonsurgical options are generally reserved for patients who refuse a very invasive treatment or cannot tolerate a surgical procedure. We report a case of cSCC successfully treated with intralesional methotrexate.
{"title":"A case of grade 3 squamous cell carcinoma successfully treated with methotrexate","authors":"Giovanni Sarracco, Fabio Rinaldi, Francesco Cusano","doi":"10.4081/dr.2024.9647","DOIUrl":"https://doi.org/10.4081/dr.2024.9647","url":null,"abstract":"Cutaneous squamous cell carcinoma (cSCC) is a nonmelanoma skin cancer whose lesions mostly arise on lightexposed sites. Patients with compromised immunity, Fitzpatrick I or II skin phototype, and previous burn scars or radiations are more at risk of developing it. The treatment of choice for cSCC is surgery; however nonsurgical options are generally reserved for patients who refuse a very invasive treatment or cannot tolerate a surgical procedure. We report a case of cSCC successfully treated with intralesional methotrexate.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstracts from the Italian Melanoma Intergroup (IMI) XXIX National Congress
意大利黑色素瘤协会（IMI）第二十九届全国大会摘要
{"title":"XXIX Italian Melanoma Intergroup National Congress | 29 September - 1 October 2023, Naples (Italy)","authors":"Italian Melanoma Intergroup (IMI)","doi":"10.4081/dr.2024.9975","DOIUrl":"https://doi.org/10.4081/dr.2024.9975","url":null,"abstract":"Abstracts from the Italian Melanoma Intergroup (IMI) XXIX National Congress","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140436630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Condorelli, A. Paganelli, Chiara Marraccini, Elena Ficarelli, Alfonso Motolese, Luca Contu, Alberico Motolese
Systemic sclerosis (SS) is a complex connective tissue disease characterized by vasculopathy and progressive fibrosis, primarily considered an autoimmune disorder. SS can affect multiple organs and tissues, including the skin, respiratory, gastrointestinal, genitourinary, cardiovascular, and musculoskeletal systems. Skin involvement is common, and SS-related ulcers, especially digital ulcers, occur in roughly 50% of patients. These ulcers not only cause pain but also significantly impact patients' quality of life, and in severe cases, they can lead to infection, gangrene, and amputation. The search for novel therapies for scleroderma-related ulcers remains an ongoing research area. Platelet-rich plasma (PRP) has been investigated as a potential treatment for difficult-to-heal ulcers, including diabetic, pressure, and vascular ulcers. In this study, we share our experience in treating scleroderma ulcers with PRP. Ten patients with confirmed SS and chronic skin ulcers lasting at least six weeks, which had not responded to conventional treatments, were selected for the study. Homologous PRP gel was prepared and applied once a week for up to eight weeks. The ulcers were documented photographically before and after PRP treatment, and pain levels were assessed using a visual analog scale (VAS). We also conducted a systematic review of the literature focusing on the use of PRP in the setting of SS. The results from our casuistry showed that the ten patients, including eight females and two males with a median age of 52.5 years, had ulcer sizes ranging from 0.78 cm2 to 28.26 cm2. The ulcers were located on fingers, legs, and heels, and they were associated with various forms of SS, including limited and diffuse cutaneous involvement. Raynaud's phenomenon was prevalent, and two patients exhibited organ involvement. The average ulcer size at the end of PRP treatment decreased significantly, with a 78% reduction in ulcered area. Pain levels also markedly improved, as indicated by a reduction in VAS scores. With regards to systematic revision of literature, we retrieved 45 cases of SS treated with PRP-based therapeutic regimes. However, only a minority of them (n=16) underwent PRP treatment for the treatment of SS-related ulcers. An improvement in wound size and pain has been documented in all cases. Taken together, these data highlight the potential benefits of using homologous PRP in the treatment of scleroderma ulcers, emphasizing its positive impact on ulcer size reduction and pain relief.
{"title":"Platelet-rich plasma for the treatment of scleroderma-associated ulcers: a single-center experience and literature review","authors":"A. Condorelli, A. Paganelli, Chiara Marraccini, Elena Ficarelli, Alfonso Motolese, Luca Contu, Alberico Motolese","doi":"10.4081/dr.2024.9878","DOIUrl":"https://doi.org/10.4081/dr.2024.9878","url":null,"abstract":"Systemic sclerosis (SS) is a complex connective tissue disease characterized by vasculopathy and progressive fibrosis, primarily considered an autoimmune disorder. SS can affect multiple organs and tissues, including the skin, respiratory, gastrointestinal, genitourinary, cardiovascular, and musculoskeletal systems. Skin involvement is common, and SS-related ulcers, especially digital ulcers, occur in roughly 50% of patients. These ulcers not only cause pain but also significantly impact patients' quality of life, and in severe cases, they can lead to infection, gangrene, and amputation. The search for novel therapies for scleroderma-related ulcers remains an ongoing research area. Platelet-rich plasma (PRP) has been investigated as a potential treatment for difficult-to-heal ulcers, including diabetic, pressure, and vascular ulcers. In this study, we share our experience in treating scleroderma ulcers with PRP. Ten patients with confirmed SS and chronic skin ulcers lasting at least six weeks, which had not responded to conventional treatments, were selected for the study. Homologous PRP gel was prepared and applied once a week for up to eight weeks. The ulcers were documented photographically before and after PRP treatment, and pain levels were assessed using a visual analog scale (VAS). We also conducted a systematic review of the literature focusing on the use of PRP in the setting of SS. The results from our casuistry showed that the ten patients, including eight females and two males with a median age of 52.5 years, had ulcer sizes ranging from 0.78 cm2 to 28.26 cm2. The ulcers were located on fingers, legs, and heels, and they were associated with various forms of SS, including limited and diffuse cutaneous involvement. Raynaud's phenomenon was prevalent, and two patients exhibited organ involvement. The average ulcer size at the end of PRP treatment decreased significantly, with a 78% reduction in ulcered area. Pain levels also markedly improved, as indicated by a reduction in VAS scores. With regards to systematic revision of literature, we retrieved 45 cases of SS treated with PRP-based therapeutic regimes. However, only a minority of them (n=16) underwent PRP treatment for the treatment of SS-related ulcers. An improvement in wound size and pain has been documented in all cases. Taken together, these data highlight the potential benefits of using homologous PRP in the treatment of scleroderma ulcers, emphasizing its positive impact on ulcer size reduction and pain relief.","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140443930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-16eCollection Date: 2024-06-14DOI: 10.4081/dr.2023.9891
Ernesto De Piano, Pietro Rubegni, Vittoria Cioppa
{"title":"A spear flap surgical revision.","authors":"Ernesto De Piano, Pietro Rubegni, Vittoria Cioppa","doi":"10.4081/dr.2023.9891","DOIUrl":"10.4081/dr.2023.9891","url":null,"abstract":"","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11228572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 55-year-old male presented with a recurrent infiltrative basal cell carcinoma of the right nasal ala. Previous incomplete excision was repaired with second intention healing resulting in a contracted ala with columellar deviation and nostril asymmetry. [...]
{"title":"A spear flap surgical revision","authors":"E. De Piano, Pietro Rubegni, Vittoria Cioppa","doi":"10.4081/dr.2024.9891","DOIUrl":"https://doi.org/10.4081/dr.2024.9891","url":null,"abstract":"A 55-year-old male presented with a recurrent infiltrative basal cell carcinoma of the right nasal ala. Previous incomplete excision was repaired with second intention healing resulting in a contracted ala with columellar deviation and nostril asymmetry. [...]","PeriodicalId":11049,"journal":{"name":"Dermatology Reports","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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