Pub Date : 2023-03-16DOI: 10.2174/04666230316121757
A. A. Zaabi, R. Pradhan, L. Ahmed, N. A. Al Kaabi, Waddah Ibrahim El Subki
To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted. Real-world evidence from the Middle East about the effectiveness of COVID-19 vaccination is still lacking. We included patients admitted to two tertiary hospitals from October 2020 to July 2022. Patients were categorized into non-vaccinated, partially-vaccinated, and fully-vaccinated groups. To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted. A total of 2277 cases were included, with 27.49% being non-vaccinated. The monthly trend of admitted patients dropped from 1264 (56.50%) cases in the first half of 2021 to 194 (8.67%) cases in the first half of 2022, with a reduction rate of 84.65%. The trend of ICU admission followed the overall hospital admission rate, with an overall CFR of 0.88%, 95% CI (0.54% to 1.35%), and a virulence rate of 1.76%, 95% CI (1.26% to 2.38%). The incidence of ICU admission in the unvaccinated group was 4.79%, compared to 0% and 0.97% in the partially-vaccinated and fully-vaccinated groups, respectively (p <0.001). The CFR was significantly (p <0.001) higher in the unvaccinated group 2.88%, 95% CI (1.71 to 4.51) than in the partially-vaccinated 0%, 95% CI (0% to 0.59%) and fully-vaccinated groups 0.19%, 95% CI (0.02% to 0.70%). Among the study population, COVID-19 vaccines showed promising efficacy in reducing the trend of COVID-19-related hospitalization, ICU admission, and mortality. Full vaccination might reduce the burden of COVID-19 on healthcare. A total of 2277 cases were included, with 27.49 None
{"title":"Impact of COVID-19 Vaccination on the Trend of Hospital Admission and Mortality in Two Tertiary Care Hospitals in the United Arab Emirates: A Retrospective Study","authors":"A. A. Zaabi, R. Pradhan, L. Ahmed, N. A. Al Kaabi, Waddah Ibrahim El Subki","doi":"10.2174/04666230316121757","DOIUrl":"https://doi.org/10.2174/04666230316121757","url":null,"abstract":"\u0000\u0000To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted.\u0000\u0000\u0000\u0000Real-world evidence from the Middle East about the effectiveness of COVID-19 vaccination is still lacking.\u0000\u0000\u0000\u0000We included patients admitted to two tertiary hospitals from October 2020 to July 2022. Patients were categorized into non-vaccinated, partially-vaccinated, and fully-vaccinated groups.\u0000\u0000\u0000\u0000To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted.\u0000\u0000\u0000\u0000A total of 2277 cases were included, with 27.49% being non-vaccinated. The monthly trend of admitted patients dropped from 1264 (56.50%) cases in the first half of 2021 to 194 (8.67%) cases in the first half of 2022, with a reduction rate of 84.65%. The trend of ICU admission followed the overall hospital admission rate, with an overall CFR of 0.88%, 95% CI (0.54% to 1.35%), and a virulence rate of 1.76%, 95% CI (1.26% to 2.38%). The incidence of ICU admission in the unvaccinated group was 4.79%, compared to 0% and 0.97% in the partially-vaccinated and fully-vaccinated groups, respectively (p <0.001). The CFR was significantly (p <0.001) higher in the unvaccinated group 2.88%, 95% CI (1.71 to 4.51) than in the partially-vaccinated 0%, 95% CI (0% to 0.59%) and fully-vaccinated groups 0.19%, 95% CI (0.02% to 0.70%).\u0000\u0000\u0000\u0000Among the study population, COVID-19 vaccines showed promising efficacy in reducing the trend of COVID-19-related hospitalization, ICU admission, and mortality. Full vaccination might reduce the burden of COVID-19 on healthcare.\u0000\u0000\u0000\u0000A total of 2277 cases were included, with 27.49\u0000\u0000\u0000\u0000None\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124002192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-13DOI: 10.2174/04666230313100005
M. Nasir, Saeed Alzaabi
Eosinophilic cystitis is a rare inflammatory cystitis of unknown origin. Common symptoms include urinary frequency, urgency, pain, and recurrent urinary tract infections. Currently used treatments include corticosteroids, anti-inflammatory drugs, antihistamines, and antibiotics. Here we present a case of successful treatment of eosinophilic cystitis with mepolizumab. A 41-year-old female presented with urinary frequency, urgency, and suprapubic pain. She underwent multiple tests including cystoscopy and biopsy, which revealed a diagnosis of eosinophilic cystitis in 2000. She was initially managed with oral antihistamines and oral steroids. However, over the years her symptoms increased in frequency, intensity, and duration. Montelukast 10 mg daily started which did not show any improvement. In 2017 Mepolizumab 100 mg every 4 weeks started. The patient noted improvement after a few months, and she was tolerating her injections well without side effects and had no further flares of her condition. We present a case of eosinophilic cystitis which was refractory to multiple treatments and responded well to mepolizumab. There are no definite guidelines for the management of EC and there is no curative treatment for this disease. Mepolizumab is an anti-IL-5 monoclonal antibody and the use of mepolizumab in the management of EC that is refractory to treatment have been reported in a few cases. The use of mepolizumab has been described in different diseases associated with eosinophilic inflammation such as severe eosinophilic asthma, eosinophilic esophagitis, eosinophilic chronic obstructive pulmonary disease, and severe nasal polyposis. Mepolizumab can be considered a treatment option in EC cases refractory to the standard treatment. At this time, larger studies are needed to evaluate the efficacy and safety of mepolizumab in EC.
{"title":"A Case of Eosinophilic Cystitis treated with Mepolizumab","authors":"M. Nasir, Saeed Alzaabi","doi":"10.2174/04666230313100005","DOIUrl":"https://doi.org/10.2174/04666230313100005","url":null,"abstract":"\u0000\u0000Eosinophilic cystitis is a rare inflammatory cystitis of unknown origin. Common symptoms include urinary frequency, urgency, pain, and recurrent urinary tract infections. Currently used treatments include corticosteroids, anti-inflammatory drugs, antihistamines, and antibiotics. Here we present a case of successful treatment of eosinophilic cystitis with mepolizumab.\u0000\u0000\u0000\u0000A 41-year-old female presented with urinary frequency, urgency, and suprapubic pain. She underwent multiple tests including cystoscopy and biopsy, which revealed a diagnosis of eosinophilic cystitis in 2000. She was initially managed with oral antihistamines and oral steroids. However, over the years her symptoms increased in frequency, intensity, and duration. Montelukast 10 mg daily started which did not show any improvement. In 2017 Mepolizumab 100 mg every 4 weeks started. The patient noted improvement after a few months, and she was tolerating her injections well without side effects and had no further flares of her condition.\u0000\u0000\u0000\u0000We present a case of eosinophilic cystitis which was refractory to multiple treatments and responded well to mepolizumab. There are no definite guidelines for the management of EC and there is no curative treatment for this disease. Mepolizumab is an anti-IL-5 monoclonal antibody and the use of mepolizumab in the management of EC that is refractory to treatment have been reported in a few cases. The use of mepolizumab has been described in different diseases associated with eosinophilic inflammation such as severe eosinophilic asthma, eosinophilic esophagitis, eosinophilic chronic obstructive pulmonary disease, and severe nasal polyposis.\u0000\u0000\u0000\u0000Mepolizumab can be considered a treatment option in EC cases refractory to the standard treatment. At this time, larger studies are needed to evaluate the efficacy and safety of mepolizumab in EC.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124730340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-08DOI: 10.2174/04666230308144244
T. Chand, Norbert Dreier, Urfan Ul Haq, F. Hachem, Vikram Kumar
Pulmonary metastasis of pregnancy-related rare gestational trophoblastic disease is common, and a patient’s rapid clinical deterioration leads to a poor prognosis. We report a case of a non-pregnant woman with severe respiratory symptoms masquerading as pulmonary infection who was diagnosed with pulmonary metastasis of the gestational trophoblastic disease. The timely diagnosis of pulmonary metastasis was the key aspect in the management of our case, and she survived and was discharged to home after a long hospitalization course.
{"title":"Diagnostic and Management Challenges of Rapid Lung Metastasis of Gestational Trophoblastic Neoplasia after a Non-molar Pregnancy: A Case Report","authors":"T. Chand, Norbert Dreier, Urfan Ul Haq, F. Hachem, Vikram Kumar","doi":"10.2174/04666230308144244","DOIUrl":"https://doi.org/10.2174/04666230308144244","url":null,"abstract":"\u0000\u0000Pulmonary metastasis of pregnancy-related rare gestational trophoblastic disease is common, and a patient’s rapid clinical deterioration leads to a poor prognosis.\u0000\u0000\u0000\u0000We report a case of a non-pregnant woman with severe respiratory symptoms masquerading as pulmonary infection who was diagnosed with pulmonary metastasis of the gestational trophoblastic disease.\u0000\u0000\u0000\u0000The timely diagnosis of pulmonary metastasis was the key aspect in the management of our case, and she survived and was discharged to home after a long hospitalization course.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114198584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-08DOI: 10.2174/04666230308141033
I. Vogiatzis, T. Konstantinou, E. Sdogkos
Drug-induced thrombocytopenia (DIT) is a condition characterized by low platelet count after administration of a variety of drugs. It is most commonly seen in patients treated with heparin. Its diagnosis is complicated when more than one DIT-causing drug is co-administered. Patients with thrombocytopenia may present with minor or major hemorrhages, depending on the severity of the recess of the platelets. We herein report an uncommon presentation of acute IIb/IIIa glycoprotein inhibitor-induced thrombocytopenia in a 50-year-old male who suffered from myocardial infarction. Serial complete blood counts revealed low platelet counts, rising after discontinuation of the administered IIb/IIIa inhibitor. Recovery was prompt, complete, and sustained with minimal costs. This report highlights the importance of prompt recognition of severe thrombocytopenia caused by IIb/IIIa inhibitors, particularly tirofiban, by measuring platelet count before and after the initiation of tirofiban, as it can be resolved by the interruption of its infusion and early supportive treatment.
{"title":"Acute Thrombocytopenia after Administration of Heparin and Tirofiban: Differential Diagnosis and Treatment","authors":"I. Vogiatzis, T. Konstantinou, E. Sdogkos","doi":"10.2174/04666230308141033","DOIUrl":"https://doi.org/10.2174/04666230308141033","url":null,"abstract":"\u0000\u0000Drug-induced thrombocytopenia (DIT) is a condition characterized by low platelet count after administration of a variety of drugs. It is most commonly seen in patients treated with heparin. Its diagnosis is complicated when more than one DIT-causing drug is co-administered. Patients with thrombocytopenia may present with minor or major hemorrhages, depending on the severity of the recess of the platelets.\u0000\u0000\u0000\u0000We herein report an uncommon presentation of acute IIb/IIIa glycoprotein inhibitor-induced thrombocytopenia in a 50-year-old male who suffered from myocardial infarction. Serial complete blood counts revealed low platelet counts, rising after discontinuation of the administered IIb/IIIa inhibitor. Recovery was prompt, complete, and sustained with minimal costs.\u0000\u0000\u0000\u0000This report highlights the importance of prompt recognition of severe thrombocytopenia caused by IIb/IIIa inhibitors, particularly tirofiban, by measuring platelet count before and after the initiation of tirofiban, as it can be resolved by the interruption of its infusion and early supportive treatment.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133938576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-02DOI: 10.2174/04666230302120808
N. Khan, Ajwan Abdulmonem Hubail Al-Najar, Tanzima Tabassum, Fathima Leila Thaliffdeen, Safa Jawad Kadhum, A. S. Karanghadan
Smoking in any form is a significant risk factor for developing cardiovascular diseases, chronic obstructive pulmonary disease, lung cancer, and other oxidative damage-induced diseases. The increasing global trend of E-cigarettes has led traditional smokers to perceive them as a safer option. Smoking in any form is a significant risk factor in developing cardiovascular diseases, chronic obstructive pulmonary disease, lung cancer, and oxidative damage. The global trend in E-cigarettes has led traditional smokers to believe it to be the safer option as it does not burn tobacco. This study aimed to compare the levels of malondialdehyde (MDA) as a marker of oxidative damage and high-sensitivity C-reactive protein (hs-CRP) as a marker of inflammation between pure E-cigarette users and tobacco poly-users (smoking combinations of traditional products). Moreover, it also evaluated the influence of Body Mass Index, frequency, and duration of vaping/smoking on these biomarkers. This study aimed to compare the differences in the levels of Malondialdehyde (MDA) as a marker of oxidative damage and high sensitivity C-reactive protein (hs-CRP) as a marker of inflammation between Pure E-cigarette users and polyusers who smoke combinations of different types of tobacco. Further, observe the influence of Body Mass Index, frequency, and duration of vaping/smoking on the biomarkers between the two groups. This analytical cross-sectional pilot study included 40 males aged 18-25 (20 pure E-cigarette users and 20 tobacco poly-users). MDA and hs-CRP were estimated on serum, and SPSS-Version 28.0.1.1 was used for data analysis. Mean hs-CRP and MDA levels for the two groups were compared using the Mann-Whitney-U test. This analytical cross-sectional pilot study was conducted with 40 males aged 18-25 (20 Pure E-cigarette users and 20 tobacco polyusers). MDA and hs-CRP were estimated on serum using standard procedures. SPSS Version 28.0.1.1 was used for data analysis. Mean hs-CRP and MDA levels were recorded for the two groups, and a comparison was made using the Mann-Whitney test. Mean level of hs-CRP between the two groups was not significantly different. However, MDA levels were lower in pure E-cigarette users than in tobacco poly-users, especially among those with normal BMI and those who vaped/smoked more frequently and for a longer duration The mean level of hs-CRP between both groups was not significantly different; however, MDA levels were lower in Pure E-cigarette users than in tobacco polyusers, especially among those with normal BMI, those who vaped/smoked more frequently, and those who have been vaping/smoking for years. Oxidative damage was lesser for pure E-cigarette users and could potentially be the less harmful option than tobacco poly-use. However, E-cigarettes are not the safest substitute for conventional smoking as it causes a similar extent of risk for inflammation-related CVD. Findings need further exploration to study the lo
{"title":"Electronic Cigarettes Versus Tobacco Poly Use: Reduced Oxidative Stress but Similar Inflammatory Effect","authors":"N. Khan, Ajwan Abdulmonem Hubail Al-Najar, Tanzima Tabassum, Fathima Leila Thaliffdeen, Safa Jawad Kadhum, A. S. Karanghadan","doi":"10.2174/04666230302120808","DOIUrl":"https://doi.org/10.2174/04666230302120808","url":null,"abstract":"\u0000\u0000Smoking in any form is a significant risk factor for developing cardiovascular diseases, chronic obstructive pulmonary disease, lung cancer, and other oxidative damage-induced diseases. The increasing global trend of E-cigarettes has led traditional smokers to perceive them as a safer option.\u0000\u0000\u0000\u0000Smoking in any form is a significant risk factor in developing cardiovascular diseases, chronic obstructive pulmonary disease, lung cancer, and oxidative damage. The global trend in E-cigarettes has led traditional smokers to believe it to be the safer option as it does not burn tobacco.\u0000\u0000\u0000\u0000This study aimed to compare the levels of malondialdehyde (MDA) as a marker of oxidative damage and high-sensitivity C-reactive protein (hs-CRP) as a marker of inflammation between pure E-cigarette users and tobacco poly-users (smoking combinations of traditional products). Moreover, it also evaluated the influence of Body Mass Index, frequency, and duration of vaping/smoking on these biomarkers.\u0000\u0000\u0000\u0000This study aimed to compare the differences in the levels of Malondialdehyde (MDA) as a marker of oxidative damage and high sensitivity C-reactive protein (hs-CRP) as a marker of inflammation between Pure E-cigarette users and polyusers who smoke combinations of different types of tobacco. Further, observe the influence of Body Mass Index, frequency, and duration of vaping/smoking on the biomarkers between the two groups.\u0000\u0000\u0000\u0000This analytical cross-sectional pilot study included 40 males aged 18-25 (20 pure E-cigarette users and 20 tobacco poly-users). MDA and hs-CRP were estimated on serum, and SPSS-Version 28.0.1.1 was used for data analysis. Mean hs-CRP and MDA levels for the two groups were compared using the Mann-Whitney-U test.\u0000\u0000\u0000\u0000This analytical cross-sectional pilot study was conducted with 40 males aged 18-25 (20 Pure E-cigarette users and 20 tobacco polyusers). MDA and hs-CRP were estimated on serum using standard procedures. SPSS Version 28.0.1.1 was used for data analysis. Mean hs-CRP and MDA levels were recorded for the two groups, and a comparison was made using the Mann-Whitney test.\u0000\u0000\u0000\u0000Mean level of hs-CRP between the two groups was not significantly different. However, MDA levels were lower in pure E-cigarette users than in tobacco poly-users, especially among those with normal BMI and those who vaped/smoked more frequently and for a longer duration\u0000\u0000\u0000\u0000The mean level of hs-CRP between both groups was not significantly different; however, MDA levels were lower in Pure E-cigarette users than in tobacco polyusers, especially among those with normal BMI, those who vaped/smoked more frequently, and those who have been vaping/smoking for years.\u0000\u0000\u0000\u0000Oxidative damage was lesser for pure E-cigarette users and could potentially be the less harmful option than tobacco poly-use. However, E-cigarettes are not the safest substitute for conventional smoking as it causes a similar extent of risk for inflammation-related CVD. Findings need further exploration to study the lo","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132427138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-02DOI: 10.2174/04666230302122204
Rohan Rishabh Susarla, Rania Zein Eldin, Ritika Coelho
The COVID-19 pandemic has dominated the last two years of the life of young individuals from every aspect. Medical illness associated with COVID-19 is only one element of the detrimental impact that it has had. The psychological, educational, and social aspects of young individuals have been affected with potentially far-reaching effects. The aim of this review is to determine the negative impact of COVID-19 in each of these areas and inform future practices or policies on the management of young individuals impacted by COVID-19 or future pandemics of this magnitude. We have collated and analyzed data available on the psychosocial, educational, and social aspects of young individuals in an attempt to understand the negative impact of COVID-19 on this group. Data were collected from an extensive Medline search of relevant articles relating to the effect of COVID-19 on individuals less than eighteen years. Our results show that although young individuals experienced a milder form of COVID-19 in the pandemic, conditions, such as anxiety, depression, and loss of routine, have caused considerable comorbidities in this population. Young individuals have also experienced a greater rise in obesity and a higher incidence of myopia. A key finding of this review showed that children with special needs experienced a lack of continuity of care. Additionally, distant and digital learning presented challenges for children from different backgrounds. Concerns regarding wider issues, such as finance, have also directly impacted young individuals. Vaccination for COVID-19 among children has also raised important ethical issues. COVID-19 has negatively impacted the psychological, physical, and emotional needs of young individuals with potentially far-reaching consequences. A combined psychosocial and clinical approach to tackling the specific needs of young individuals is essential to support the needs and management of individuals affected by the pandemic. The findings of our review recommend measures to include balancing screen time with outdoor activity and encouraging the continued education of children regarding good health practices and vaccination in particular. We hope that this will inform future practices or policies on the management of young individuals impacted by COVID-19 or future pandemics of this magnitude.
{"title":"Effects of COVID-19 Pandemic on Young Individuals - A Mini Review","authors":"Rohan Rishabh Susarla, Rania Zein Eldin, Ritika Coelho","doi":"10.2174/04666230302122204","DOIUrl":"https://doi.org/10.2174/04666230302122204","url":null,"abstract":"\u0000\u0000The COVID-19 pandemic has dominated the last two years of the life of young individuals from every aspect. Medical illness associated with COVID-19 is only one element of the detrimental impact that it has had. The psychological, educational, and social aspects of young individuals have been affected with potentially far-reaching effects. The aim of this review is to determine the negative impact of COVID-19 in each of these areas and inform future practices or policies on the management of young individuals impacted by COVID-19 or future pandemics of this magnitude.\u0000\u0000\u0000\u0000We have collated and analyzed data available on the psychosocial, educational, and social aspects of young individuals in an attempt to understand the negative impact of COVID-19 on this group. Data were collected from an extensive Medline search of relevant articles relating to the effect of COVID-19 on individuals less than eighteen years.\u0000\u0000\u0000\u0000Our results show that although young individuals experienced a milder form of COVID-19 in the pandemic, conditions, such as anxiety, depression, and loss of routine, have caused considerable comorbidities in this population. Young individuals have also experienced a greater rise in obesity and a higher incidence of myopia. A key finding of this review showed that children with special needs experienced a lack of continuity of care. Additionally, distant and digital learning presented challenges for children from different backgrounds. Concerns regarding wider issues, such as finance, have also directly impacted young individuals. Vaccination for COVID-19 among children has also raised important ethical issues.\u0000\u0000\u0000\u0000COVID-19 has negatively impacted the psychological, physical, and emotional needs of young individuals with potentially far-reaching consequences. A combined psychosocial and clinical approach to tackling the specific needs of young individuals is essential to support the needs and management of individuals affected by the pandemic. The findings of our review recommend measures to include balancing screen time with outdoor activity and encouraging the continued education of children regarding good health practices and vaccination in particular. We hope that this will inform future practices or policies on the management of young individuals impacted by COVID-19 or future pandemics of this magnitude.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"214 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117098107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-23DOI: 10.2174/04666230223103243
Shriya Devendra Tayade, Vaishnavi Bose, Ashna Ameer, Maryam Essa Alfard Alali, M. Abdulrahim
Omental infarction is an entity that seldom manifests with gastrointestinal symptoms and often presents a diagnostic challenge. Due to its non-specific presentation, it is usually not included as a differential diagnosis of acute abdomen, especially in an emergency setting. We present the case of a 38-year-old overweight female, seen in the emergency department, with a complaint of sudden onset of worsening epigastric abdominal pain for four days. The pain became more localized at the right iliac fossa two days before the admission. A physical examination revealed severe right iliac fossa tenderness and positive rebound tenderness. A computed tomography of the abdomen was done and showed a localized area of mesenteric fat stranding in the right lumbar region reaching up to the inferior border of the right lobe of the liver with adjacent peritoneal fold thickening, likely suggesting inflammatory etiology. However, the appendix was visualized normally with a mild enhancement of the distal part suggesting secondary mild acute appendicitis. A decision for diagnostic laparoscopy was made, where we found a 4x4 cm infarcted greater omental segment, which was excised and sent for histopathology. Idiopathic omental infarction is a rare cause of acute abdomen in adults and needs to be considered as a potential differential diagnosis, especially if the clinical finding does not correspond with common conditions, like acute appendicitis.
{"title":"Laparoscopic Approach to a Patient with Omental Infarction: A Case Report","authors":"Shriya Devendra Tayade, Vaishnavi Bose, Ashna Ameer, Maryam Essa Alfard Alali, M. Abdulrahim","doi":"10.2174/04666230223103243","DOIUrl":"https://doi.org/10.2174/04666230223103243","url":null,"abstract":"\u0000\u0000Omental infarction is an entity that seldom manifests with gastrointestinal symptoms and often presents a diagnostic challenge. Due to its non-specific presentation, it is usually not included as a differential diagnosis of acute abdomen, especially in an emergency setting.\u0000\u0000\u0000\u0000We present the case of a 38-year-old overweight female, seen in the emergency department, with a complaint of sudden onset of worsening epigastric abdominal pain for four days. The pain became more localized at the right iliac fossa two days before the admission. A physical examination revealed severe right iliac fossa tenderness and positive rebound tenderness. \u0000A computed tomography of the abdomen was done and showed a localized area of mesenteric fat stranding in the right lumbar region reaching up to the inferior border of the right lobe of the liver with adjacent peritoneal fold thickening, likely suggesting inflammatory etiology. However, the appendix was visualized normally with a mild enhancement of the distal part suggesting secondary mild acute appendicitis. \u0000A decision for diagnostic laparoscopy was made, where we found a 4x4 cm infarcted greater omental segment, which was excised and sent for histopathology.\u0000\u0000\u0000\u0000Idiopathic omental infarction is a rare cause of acute abdomen in adults and needs to be considered as a potential differential diagnosis, especially if the clinical finding does not correspond with common conditions, like acute appendicitis.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131466863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-08DOI: 10.2174/04666230208125739
Ramya Kundayi Ravi, Huda Mohamed Ali Rasheed, Mona Gamal Mohamed
The COVID-19 pandemic remains a major public health. There are still many mysteries about the virus and remains out of control in many parts of the world, therefore, it has been declared a worldwide pandemic by the WHO. Hence it is important to devise and implement strategies to promote vaccination across all age groups including children. The study aimed to evaluate the parental acceptability and concerns towards vaccinating their children against COVID-19. The study adopted a cross-sectional design and information regarding sociodemographic details, acceptability, and concerns towards vaccinating their children that were collected using a structured questionnaire, administered to parents using online and paper-based methods. A total of 366 parents were selected using purposive sampling from the Emirate of Ras Al Khaimah, from November 2021 to February 2022. Of all, 5.3% (56) of the parents expressed a high level of concern regarding vaccinating their children against COVID-19 while 80.6% (295) expressed a medium level and 4.1% (15) expressed a low level of concern. Parental acceptability was found to be medium and high among 71 % (260) and 8.8% (69) of the parents respectively as opposed to 10.1% (37) who were reluctant (low) to get their children vaccinated. The most important concerns for the low acceptance of COVID-19 vaccination were safety, side effects, and effectiveness of the vaccination. The study reveals the need to initiate more targeted interventions to improve the acceptability and alleviate the concerns of parents about vaccinating their children against COVID-19.
{"title":"Acceptability and Concerns Towards Covid -19 Vaccination among Parents; A Cross - Sectional Survey in Ras Al-Khaimah, United Arab Emirates","authors":"Ramya Kundayi Ravi, Huda Mohamed Ali Rasheed, Mona Gamal Mohamed","doi":"10.2174/04666230208125739","DOIUrl":"https://doi.org/10.2174/04666230208125739","url":null,"abstract":"\u0000\u0000The COVID-19 pandemic remains a major public health. There are still many mysteries about the virus and remains out of control in many parts of the world, therefore, it has been declared a worldwide pandemic by the WHO. Hence it is important to devise and implement strategies to promote vaccination across all age groups including children.\u0000\u0000\u0000\u0000The study aimed to evaluate the parental acceptability and concerns towards vaccinating their children against COVID-19.\u0000\u0000\u0000\u0000The study adopted a cross-sectional design and information regarding sociodemographic details, acceptability, and concerns towards vaccinating their children that were collected using a structured questionnaire, administered to parents using online and paper-based methods. A total of 366 parents were selected using purposive sampling from the Emirate of Ras Al Khaimah, from November 2021 to February 2022.\u0000\u0000\u0000\u0000Of all, 5.3% (56) of the parents expressed a high level of concern regarding vaccinating their children against COVID-19 while 80.6% (295) expressed a medium level and 4.1% (15) expressed a low level of concern. Parental acceptability was found to be medium and high among 71 % (260) and 8.8% (69) of the parents respectively as opposed to 10.1% (37) who were reluctant (low) to get their children vaccinated. The most important concerns for the low acceptance of COVID-19 vaccination were safety, side effects, and effectiveness of the vaccination.\u0000\u0000\u0000\u0000The study reveals the need to initiate more targeted interventions to improve the acceptability and alleviate the concerns of parents about vaccinating their children against COVID-19.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129657398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-03DOI: 10.2174/04666230203113909
Shahbaz Haroon, S. Khatavkar, Chhaya. M Suryawanshi, Deepali Rahul Patil
A multidisciplinary team that includes an endocrinologist, radiologist, anesthesiologist, and surgeon is a prerequisite for adrenal gland surgeries. The prime indications for adrenal gland surgery can include both hormonal and non-hormonal secreting tumors. Adrenal hormone-secreting tumors usually present to the anesthesiologist with a unique set of challenges that require a good preoperative evaluation and hemodynamic control, corrections of all electrolytes and metabolic imbalances, a carefully planned anesthetic strategy, detailed knowledge about the specific diseases, maintaining of postoperative adrenal function, and finally a good collaboration with other involved colleagues. This review will mainly focus on endocrine issues and anesthetic management during the resection of a hormone-secreting adrenal gland tumor. This is a case report of a 1.5-year-old boy weighing 13.5 kg who was admitted to our hospital with complaints of an increase in height and weight more than appropriate for age, macroglossia, facial oedema, abnormally enlarged genitals and development of pubic hair for 6 months. On examination along with signs of precocious puberty, he had presented raised blood pressure for which he was started on medication. On ultrasonography, a 6*4 cm mass was seen in the right supra renal fossa which was confirmed on the CECT scan. He underwent surgery for the excision of the tumor mass under general anesthesia with a regional blockade (epidural). The histopathological report of the tumor specimen revealed Adrenocortical Carcinoma. The child required post-operative steroid treatment and subsequently was started on chemotherapy as well. The perioperative medical management of active Adreno Cortical Carcinomas is complex enough, but anesthesia causes even more substantial changes in physiology. Treatment with steroids helps to maintain hemodynamics to a great extent.
{"title":"Anesthetic management of a child with adrenocortical virilizing tumour excision","authors":"Shahbaz Haroon, S. Khatavkar, Chhaya. M Suryawanshi, Deepali Rahul Patil","doi":"10.2174/04666230203113909","DOIUrl":"https://doi.org/10.2174/04666230203113909","url":null,"abstract":"\u0000\u0000A multidisciplinary team that includes an endocrinologist, radiologist, anesthesiologist, and surgeon is a prerequisite for adrenal gland surgeries. The prime indications for adrenal gland surgery can include both hormonal and non-hormonal secreting tumors. Adrenal hormone-secreting tumors usually present to the anesthesiologist with a unique set of challenges that require a good preoperative evaluation and hemodynamic control, corrections of all electrolytes and metabolic imbalances, a carefully planned anesthetic strategy, detailed knowledge about the specific diseases, maintaining of postoperative adrenal function, and finally a good collaboration with other involved colleagues. This review will mainly focus on endocrine issues and anesthetic management during the resection of a hormone-secreting adrenal gland tumor.\u0000\u0000\u0000\u0000This is a case report of a 1.5-year-old boy weighing 13.5 kg who was admitted to our hospital with complaints of an increase in height and weight more than appropriate for age, macroglossia, facial oedema, abnormally enlarged genitals and development of pubic hair for 6 months. On examination along with signs of precocious puberty, he had presented raised blood pressure for which he was started on medication.\u0000\u0000\u0000\u0000On ultrasonography, a 6*4 cm mass was seen in the right supra renal fossa which was confirmed on the CECT scan. He underwent surgery for the excision of the tumor mass under general anesthesia with a regional blockade (epidural). The histopathological report of the tumor specimen revealed Adrenocortical Carcinoma. The child required post-operative steroid treatment and subsequently was started on chemotherapy as well.\u0000\u0000\u0000\u0000The perioperative medical management of active Adreno Cortical Carcinomas is complex enough, but anesthesia causes even more substantial changes in physiology. Treatment with steroids helps to maintain hemodynamics to a great extent.\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117240114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-03DOI: 10.2174/04666230203113102
Faraz Ahmed Baig, Faraz Hassan Mirza, S. Syed, Ashok Kumar V, Moazam Ali Shahid
Presepsin is a soluble analog of CD14, recently validated as a new biomarker for sepsis. Different cut-off levels of Presepsin for the diagnosis of sepsis have been proposed however, the optimum threshold for early clinical discrimination of sepsis from non-infectious conditions remains unknown. Presepsin is a soluble analog of CD14, recently validated as a new biomarker for sepsis. Different cut-off levels of Presepsin for the diagnosis of sepsis have been proposed, however the optimum threshold for early clinical discrimination of sepsis from non-infectious conditions remained unknown. This work was undertaken to define the reference interval of Presepsin for Sepsis according to the CLSI C28-A3c approved guideline. This study evaluated the reference interval of Presepsin for early diagnosis and differentiation of Sepsis. Reference individuals (N=72) receiving in-patient care at ICU for sepsis and complications were selected for the study. Presepsin concentrations were measured by enzyme-linked immunosorbent assay. Reference limits were calculated using the non-parametric robust method. Reference individuals (N=72) receiving in-patient care at ICU for sepsis and complications were selected for the study. Presepsin concentrations were measured by enzyme linked immunosorbent assay. Reference limits were calculated using the non-parametric robust method. Overall, the reference range for Presepsin in sepsis patients was 24.2 -872.2 pg/mL (90% confidence interval). Peak values for males were relatively higher than for females and the presepsin concentrations were influenced by age. Overall, the reference range for the Presepsin in sepsis patients was 24.2 -872.2 pg/mL (90% confidence interval). Peak values for males were relatively higher than females and the presepsin concentrations were influenced by age. Proposed reference interval could assist in accurate and early diagnosis of sepsis which would eventually improve the outcome in patients of all age groups. Proposed reference interval could assist in accurate and early diagnosis of sepsis which would eventually improve outcome in patients of all age groups
{"title":"Standardized Criterion of Presepsin Reference Interval for Accurate and Early Diagnosis of Sepsis","authors":"Faraz Ahmed Baig, Faraz Hassan Mirza, S. Syed, Ashok Kumar V, Moazam Ali Shahid","doi":"10.2174/04666230203113102","DOIUrl":"https://doi.org/10.2174/04666230203113102","url":null,"abstract":"\u0000\u0000Presepsin is a soluble analog of CD14, recently validated as a new biomarker for sepsis. Different cut-off levels of Presepsin for the diagnosis of sepsis have been proposed however, the optimum threshold for early clinical discrimination of sepsis from non-infectious conditions remains unknown.\u0000\u0000\u0000\u0000Presepsin is a soluble analog of CD14, recently validated as a new biomarker for sepsis. Different cut-off levels of Presepsin for the diagnosis of sepsis have been proposed, however the optimum threshold for early clinical discrimination of sepsis from non-infectious conditions remained unknown.\u0000\u0000\u0000\u0000This work was undertaken to define the reference interval of Presepsin for Sepsis according to the CLSI C28-A3c approved guideline.\u0000\u0000\u0000\u0000This study evaluated the reference interval of Presepsin for early diagnosis and differentiation of Sepsis.\u0000\u0000\u0000\u0000Reference individuals (N=72) receiving in-patient care at ICU for sepsis and complications were selected for the study. Presepsin concentrations were measured by enzyme-linked immunosorbent assay. Reference limits were calculated using the non-parametric robust method.\u0000\u0000\u0000\u0000Reference individuals (N=72) receiving in-patient care at ICU for sepsis and complications were selected for the study. Presepsin concentrations were measured by enzyme linked immunosorbent assay. Reference limits were calculated using the non-parametric robust method.\u0000\u0000\u0000\u0000Overall, the reference range for Presepsin in sepsis patients was 24.2 -872.2 pg/mL (90% confidence interval). Peak values for males were relatively higher than for females and the presepsin concentrations were influenced by age.\u0000\u0000\u0000\u0000Overall, the reference range for the Presepsin in sepsis patients was 24.2 -872.2 pg/mL (90% confidence interval). Peak values for males were relatively higher than females and the presepsin concentrations were influenced by age.\u0000\u0000\u0000\u0000Proposed reference interval could assist in accurate and early diagnosis of sepsis which would eventually improve the outcome in patients of all age groups.\u0000\u0000\u0000\u0000Proposed reference interval could assist in accurate and early diagnosis of sepsis which would eventually improve outcome in patients of all age groups\u0000","PeriodicalId":110816,"journal":{"name":"New Emirates Medical Journal","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116916369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：