Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dth2a.4
Maria-Pilar Urizar, Álvaro de la Peña, E. Gambra, A. de Castro, S. Marcos, A. Curatolo
We experimentally verify the design of a low-cost scanner that performs dynamic whole-eye scans without requiring any moving component. We present beam profiles and OCT images in an ex vivo rabbit eye.
{"title":"A low-cost, non-mechanical optical beam scanner: experimental proof-of-concept for whole-eye OCT imaging","authors":"Maria-Pilar Urizar, Álvaro de la Peña, E. Gambra, A. de Castro, S. Marcos, A. Curatolo","doi":"10.1364/boda.2023.dth2a.4","DOIUrl":"https://doi.org/10.1364/boda.2023.dth2a.4","url":null,"abstract":"We experimentally verify the design of a low-cost scanner that performs dynamic whole-eye scans without requiring any moving component. We present beam profiles and OCT images in an ex vivo rabbit eye.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126453495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/ntm.2023.ntu3c.2
Shuhao Shen, E. Du, Kai Long, Nanguang Chena
We have implemented structured illumination in a fast-scanning confocal microscope. Significant reduction in background and noise has been accomplished. It is further augmented by image resan to enable real-time acquisition of super-resolution images.
{"title":"Fast structured illumination microscopy for deep tissue super-resolution imaging","authors":"Shuhao Shen, E. Du, Kai Long, Nanguang Chena","doi":"10.1364/ntm.2023.ntu3c.2","DOIUrl":"https://doi.org/10.1364/ntm.2023.ntu3c.2","url":null,"abstract":"We have implemented structured illumination in a fast-scanning confocal microscope. Significant reduction in background and noise has been accomplished. It is further augmented by image resan to enable real-time acquisition of super-resolution images.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126351656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We investigate individual collagen fibrils using polarization SHG microscopy and find that polarization SHG is sensitive to changes in fibril structure and orientation.
我们使用偏振SHG显微镜观察单个胶原原纤维，发现偏振SHG对原纤维结构和取向的变化很敏感。
{"title":"Characterizing Hydration and Buckling in Individual Collagen Fibrils with Polarization Second Harmonic Generation Microscopy","authors":"Macaulay Harvey, R. Cisek, L. Kreplak, D. Tokarz","doi":"10.1364/omp.2023.om2e.3","DOIUrl":"https://doi.org/10.1364/omp.2023.om2e.3","url":null,"abstract":"We investigate individual collagen fibrils using polarization SHG microscopy and find that polarization SHG is sensitive to changes in fibril structure and orientation.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126765044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jtu4b.8
S. H. Kim, Ludguier D. Montejo, A. Hielscher
This work focuses on the evaluation of frequency-domain 3rd-order simplified spherical harmonics (FD-SP3) model based image reconstruction with respect to its clinical utility to diagnose rheumatoid arthritis (RA). The results presented here show that the FD-SP3 model achieves clinically relevant sensitivity (88%) and specificity (93%) that compare favorably to the ERT while maintaining significant computational advantage over the ERT.
{"title":"Diagnostic Performance of the Frequency-Domain Third- Order Simplified Spherical Harmonics (SP3) Model on Rheumatoid Arthritis in Finger Joints","authors":"S. H. Kim, Ludguier D. Montejo, A. Hielscher","doi":"10.1364/boda.2023.jtu4b.8","DOIUrl":"https://doi.org/10.1364/boda.2023.jtu4b.8","url":null,"abstract":"This work focuses on the evaluation of frequency-domain 3rd-order simplified spherical harmonics (FD-SP3) model based image reconstruction with respect to its clinical utility to diagnose rheumatoid arthritis (RA). The results presented here show that the FD-SP3 model achieves clinically relevant sensitivity (88%) and specificity (93%) that compare favorably to the ERT while maintaining significant computational advantage over the ERT.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114417950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/omp.2023.otu3e.3
J. Torra, C. Flors
We explore the use of fluorogenic amyloid probes in two super-resolution methods. A spatial resolution of 45–70 nm, low image background and long term imaging can be achieved, expanding the toolbox of super-resolution labels.
{"title":"Unconventional fluorophores for super-resolution microscopy","authors":"J. Torra, C. Flors","doi":"10.1364/omp.2023.otu3e.3","DOIUrl":"https://doi.org/10.1364/omp.2023.otu3e.3","url":null,"abstract":"We explore the use of fluorogenic amyloid probes in two super-resolution methods. A spatial resolution of 45–70 nm, low image background and long term imaging can be achieved, expanding the toolbox of super-resolution labels.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132657072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erwan Stourm, M. Lepers, Jacques Robert, S.N. Chormaic, K. Mølmer, É. Brion
We investigate how van der Waals interaction between Rydberg atoms is modified in the vicinity of an optical nanofiber with respect to free-space. This work paves the way to promising light-matter interfaces for quantum technologies.
{"title":"Rydberg Atoms In the Vicinity of an Optical Nanofiber","authors":"Erwan Stourm, M. Lepers, Jacques Robert, S.N. Chormaic, K. Mølmer, É. Brion","doi":"10.1364/oma.2023.aw1d.1","DOIUrl":"https://doi.org/10.1364/oma.2023.aw1d.1","url":null,"abstract":"We investigate how van der Waals interaction between Rydberg atoms is modified in the vicinity of an optical nanofiber with respect to free-space. This work paves the way to promising light-matter interfaces for quantum technologies.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114076076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We review recent experimental studies of an information engine, the modern realization of Maxwell’s demon. We show how to maximize performance, even with noisy measurements. Environments with added nonequilibrium fluctuations increase work-extraction rates.
{"title":"Information engines based on optical traps and feedback","authors":"Tushar K. Saha, J. Bechhoefer","doi":"10.1364/oma.2023.am4d.1","DOIUrl":"https://doi.org/10.1364/oma.2023.am4d.1","url":null,"abstract":"We review recent experimental studies of an information engine, the modern realization of Maxwell’s demon. We show how to maximize performance, even with noisy measurements. Environments with added nonequilibrium fluctuations increase work-extraction rates.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122469775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The goal of this work is to develop a tethered fluorescence instrument for directly measuring dynamic changes in circulating tumor cell numbers in the bloodstream in awake, freely moving mice in vivo.
{"title":"Tethered Fluorescence Instrument for Continuous Detection of Circulating Tumor Cell Numbers in Awake Mice","authors":"Jane Lee, C. Bellini, M. Niedre","doi":"10.1364/omp.2023.om4e.5","DOIUrl":"https://doi.org/10.1364/omp.2023.om4e.5","url":null,"abstract":"The goal of this work is to develop a tethered fluorescence instrument for directly measuring dynamic changes in circulating tumor cell numbers in the bloodstream in awake, freely moving mice in vivo.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124045858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/oma.2023.atu1d.2
Rachel E. Gariepy, Alexander B. Bard, P. Pauzauskie
Yttrium lithium fluoride crystals doped with 10% ytterbium have undergone a synthetic conjugation procedure to coat them with horseradish peroxidase. The crystals have been shown via mean fluorescence spectroscopy to still undergo photothermal cooling despite their coating of materials that photothermally heat.
{"title":"Optical Refrigeration of Enzyme-Coated Rare-Earth-Doped Fluorides","authors":"Rachel E. Gariepy, Alexander B. Bard, P. Pauzauskie","doi":"10.1364/oma.2023.atu1d.2","DOIUrl":"https://doi.org/10.1364/oma.2023.atu1d.2","url":null,"abstract":"Yttrium lithium fluoride crystals doped with 10% ytterbium have undergone a synthetic conjugation procedure to coat them with horseradish peroxidase. The crystals have been shown via mean fluorescence spectroscopy to still undergo photothermal cooling despite their coating of materials that photothermally heat.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"10 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129079354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/brain.2023.bm2b.3
W. O’Brien, A. Ortega, D. Rogers, M. Yücel, A. von Lühmann, S. Kiran, T. Ellis, D. Somers, A. Cronin-Golomb, D. Boas, B. Zimmermann
NinjaNIRS seeks to provide an open-source ecosystem to increase adoption of functional near-infrared spectroscopy (fNIRS) with integrated EEG in the real world. Co-location and high module count enables high-density, whole-head coverage of both modalities.
{"title":"NinjaNIRS: An Open-Source Ecosystem for Wearable, Whole-Head and High Density fNIRS with EEG Co-Localization","authors":"W. O’Brien, A. Ortega, D. Rogers, M. Yücel, A. von Lühmann, S. Kiran, T. Ellis, D. Somers, A. Cronin-Golomb, D. Boas, B. Zimmermann","doi":"10.1364/brain.2023.bm2b.3","DOIUrl":"https://doi.org/10.1364/brain.2023.bm2b.3","url":null,"abstract":"NinjaNIRS seeks to provide an open-source ecosystem to increase adoption of functional near-infrared spectroscopy (fNIRS) with integrated EEG in the real world. Co-location and high module count enables high-density, whole-head coverage of both modalities.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129257838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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