Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jw2a.2
Bingxue Liu, D. Boas, Xiaojun Cheng
We present a short-separation speckle contrast optical spectroscopy (ss-SCOS) system to enhance the static and slow tissue components with the multi-exposure time-based speckle contrast model to extract both the slow tissue and fast blood flow dynamics.
{"title":"Measurements of slow tissue dynamics with short-separation speckle contrast optical spectroscopy","authors":"Bingxue Liu, D. Boas, Xiaojun Cheng","doi":"10.1364/boda.2023.jw2a.2","DOIUrl":"https://doi.org/10.1364/boda.2023.jw2a.2","url":null,"abstract":"We present a short-separation speckle contrast optical spectroscopy (ss-SCOS) system to enhance the static and slow tissue components with the multi-exposure time-based speckle contrast model to extract both the slow tissue and fast blood flow dynamics.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128199889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dtu3a.5
CINDY (XIN) Chen, George T. Funkenbusch, Adam Wax
We propose to use holographic cytometry to evaluate sickle cell disease patient samples and develop artificial intelligence that can screen for sickling phenotypes.
我们建议使用全息细胞术来评估镰状细胞病患者的样本，并开发人工智能，可以筛选镰状细胞表型。
{"title":"High throughput QPM for Sickle Cell Disease Detection","authors":"CINDY (XIN) Chen, George T. Funkenbusch, Adam Wax","doi":"10.1364/boda.2023.dtu3a.5","DOIUrl":"https://doi.org/10.1364/boda.2023.dtu3a.5","url":null,"abstract":"We propose to use holographic cytometry to evaluate sickle cell disease patient samples and develop artificial intelligence that can screen for sickling phenotypes.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134346555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dtu2a.6
M. Mujat, Ankit H. Patel, N. Iftimia
Simultaneous multi-channels offset imaging provides isotropic images of retinal microstructures free of directionality artifacts and enables phase imaging in the living eye with enhanced visualization contrast.
{"title":"Retinal Phase Imaging with Multi-Channel AOSLO","authors":"M. Mujat, Ankit H. Patel, N. Iftimia","doi":"10.1364/boda.2023.dtu2a.6","DOIUrl":"https://doi.org/10.1364/boda.2023.dtu2a.6","url":null,"abstract":"Simultaneous multi-channels offset imaging provides isotropic images of retinal microstructures free of directionality artifacts and enables phase imaging in the living eye with enhanced visualization contrast.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134556189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/omp.2023.oth1e.1
Natalie Won, Josephine La Macchia, Anjola Adewale, Mandolin L Bartling, Esmat Najjar, B. Wilson, Jonathan C. Irish, M. Daly
Image quantification of fluorophore concentration based on phase-shifted sinusoidal patterns projected onto the surgical field. Results analyzed in an oral cancer mouse model and optical phantoms derived from tongue cancer patients.
{"title":"Quantitative Spatial Frequency Domain Fluorescence Imaging for Surgical Guidance: Fluorophore Concentration Estimation in Pre-Clinical Cancer Models","authors":"Natalie Won, Josephine La Macchia, Anjola Adewale, Mandolin L Bartling, Esmat Najjar, B. Wilson, Jonathan C. Irish, M. Daly","doi":"10.1364/omp.2023.oth1e.1","DOIUrl":"https://doi.org/10.1364/omp.2023.oth1e.1","url":null,"abstract":"Image quantification of fluorophore concentration based on phase-shifted sinusoidal patterns projected onto the surgical field. Results analyzed in an oral cancer mouse model and optical phantoms derived from tongue cancer patients.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133028556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/omp.2023.oth1e.6
Fernando Ivich, I. Calderon, H. Clark, M. Niedre
We present ‘ratiometric diffuse in vivo flow cytometry’ (R-DiFC), the aim of which is to measure fluorescent signals from circulating optical microsensors for continuous in vivo quantification of blood sodium levels.
{"title":"Ratiometric Diffuse in vivo Flow Cytometry for Quantification of Blood Sodium Levels Using Circulating Fluorescent Microsensors","authors":"Fernando Ivich, I. Calderon, H. Clark, M. Niedre","doi":"10.1364/omp.2023.oth1e.6","DOIUrl":"https://doi.org/10.1364/omp.2023.oth1e.6","url":null,"abstract":"We present ‘ratiometric diffuse in vivo flow cytometry’ (R-DiFC), the aim of which is to measure fluorescent signals from circulating optical microsensors for continuous in vivo quantification of blood sodium levels.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132065947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erwan Stourm, M. Lepers, Jacques Robert, S.N. Chormaic, K. Mølmer, É. Brion
We investigate how van der Waals interaction between Rydberg atoms is modified in the vicinity of an optical nanofiber with respect to free-space. This work paves the way to promising light-matter interfaces for quantum technologies.
{"title":"Rydberg Atoms In the Vicinity of an Optical Nanofiber","authors":"Erwan Stourm, M. Lepers, Jacques Robert, S.N. Chormaic, K. Mølmer, É. Brion","doi":"10.1364/oma.2023.aw1d.1","DOIUrl":"https://doi.org/10.1364/oma.2023.aw1d.1","url":null,"abstract":"We investigate how van der Waals interaction between Rydberg atoms is modified in the vicinity of an optical nanofiber with respect to free-space. This work paves the way to promising light-matter interfaces for quantum technologies.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114076076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We review recent experimental studies of an information engine, the modern realization of Maxwell’s demon. We show how to maximize performance, even with noisy measurements. Environments with added nonequilibrium fluctuations increase work-extraction rates.
{"title":"Information engines based on optical traps and feedback","authors":"Tushar K. Saha, J. Bechhoefer","doi":"10.1364/oma.2023.am4d.1","DOIUrl":"https://doi.org/10.1364/oma.2023.am4d.1","url":null,"abstract":"We review recent experimental studies of an information engine, the modern realization of Maxwell’s demon. We show how to maximize performance, even with noisy measurements. Environments with added nonequilibrium fluctuations increase work-extraction rates.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122469775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The goal of this work is to develop a tethered fluorescence instrument for directly measuring dynamic changes in circulating tumor cell numbers in the bloodstream in awake, freely moving mice in vivo.
{"title":"Tethered Fluorescence Instrument for Continuous Detection of Circulating Tumor Cell Numbers in Awake Mice","authors":"Jane Lee, C. Bellini, M. Niedre","doi":"10.1364/omp.2023.om4e.5","DOIUrl":"https://doi.org/10.1364/omp.2023.om4e.5","url":null,"abstract":"The goal of this work is to develop a tethered fluorescence instrument for directly measuring dynamic changes in circulating tumor cell numbers in the bloodstream in awake, freely moving mice in vivo.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124045858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/oma.2023.atu1d.2
Rachel E. Gariepy, Alexander B. Bard, P. Pauzauskie
Yttrium lithium fluoride crystals doped with 10% ytterbium have undergone a synthetic conjugation procedure to coat them with horseradish peroxidase. The crystals have been shown via mean fluorescence spectroscopy to still undergo photothermal cooling despite their coating of materials that photothermally heat.
{"title":"Optical Refrigeration of Enzyme-Coated Rare-Earth-Doped Fluorides","authors":"Rachel E. Gariepy, Alexander B. Bard, P. Pauzauskie","doi":"10.1364/oma.2023.atu1d.2","DOIUrl":"https://doi.org/10.1364/oma.2023.atu1d.2","url":null,"abstract":"Yttrium lithium fluoride crystals doped with 10% ytterbium have undergone a synthetic conjugation procedure to coat them with horseradish peroxidase. The crystals have been shown via mean fluorescence spectroscopy to still undergo photothermal cooling despite their coating of materials that photothermally heat.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"10 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129079354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/brain.2023.bm2b.3
W. O’Brien, A. Ortega, D. Rogers, M. Yücel, A. von Lühmann, S. Kiran, T. Ellis, D. Somers, A. Cronin-Golomb, D. Boas, B. Zimmermann
NinjaNIRS seeks to provide an open-source ecosystem to increase adoption of functional near-infrared spectroscopy (fNIRS) with integrated EEG in the real world. Co-location and high module count enables high-density, whole-head coverage of both modalities.
{"title":"NinjaNIRS: An Open-Source Ecosystem for Wearable, Whole-Head and High Density fNIRS with EEG Co-Localization","authors":"W. O’Brien, A. Ortega, D. Rogers, M. Yücel, A. von Lühmann, S. Kiran, T. Ellis, D. Somers, A. Cronin-Golomb, D. Boas, B. Zimmermann","doi":"10.1364/brain.2023.bm2b.3","DOIUrl":"https://doi.org/10.1364/brain.2023.bm2b.3","url":null,"abstract":"NinjaNIRS seeks to provide an open-source ecosystem to increase adoption of functional near-infrared spectroscopy (fNIRS) with integrated EEG in the real world. Co-location and high module count enables high-density, whole-head coverage of both modalities.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129257838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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