Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dth2a.7
Khushmeet Dhaliwal, Ehsan Imani, C. Hudson, K. Bizheva
Visual stimulus-induced changes in the human retinal blood flow were measured with a combined SD-OCT + ERG system.
使用SD-OCT + ERG联合系统测量视觉刺激引起的人视网膜血流变化。
{"title":"Stimulus-induced changes in human retinal blood flow measured with a combined OCT+ERG system","authors":"Khushmeet Dhaliwal, Ehsan Imani, C. Hudson, K. Bizheva","doi":"10.1364/boda.2023.dth2a.7","DOIUrl":"https://doi.org/10.1364/boda.2023.dth2a.7","url":null,"abstract":"Visual stimulus-induced changes in the human retinal blood flow were measured with a combined SD-OCT + ERG system.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125365958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua Pace, Srinivasarao Madduri, Shivakrishna Kallepu, P. Low, M. Niedre
The goal of this research is to develop a method to label, detect, and count circulating tumor cells directly in vivo with an injectable folate-receptor targeted fluorescent molecular probe and near infrared (NIR) light.
{"title":"Fluorescent Molecular Labeling and In Vivo Detection of Circulating Tumor Cells in Mice","authors":"Joshua Pace, Srinivasarao Madduri, Shivakrishna Kallepu, P. Low, M. Niedre","doi":"10.1364/omp.2023.ow1e.5","DOIUrl":"https://doi.org/10.1364/omp.2023.ow1e.5","url":null,"abstract":"The goal of this research is to develop a method to label, detect, and count circulating tumor cells directly in vivo with an injectable folate-receptor targeted fluorescent molecular probe and near infrared (NIR) light.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133626250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a comparative study on optical trapping dynamics for polystyrene and silica micro-particles under both continuous wave and pulsed excitations. The effect of optical nonlinearity under femtosecond pulsed excitation on trapping efficiency is investigated.
{"title":"Effect of optical nonlinearity in trapping dynamics of polystyrene and silica micro-particles under femtosecond pulsed excitation: A comparative study","authors":"S. Yadav, Abdul Alim, A. De","doi":"10.1364/oma.2023.aw1d.3","DOIUrl":"https://doi.org/10.1364/oma.2023.aw1d.3","url":null,"abstract":"We present a comparative study on optical trapping dynamics for polystyrene and silica micro-particles under both continuous wave and pulsed excitations. The effect of optical nonlinearity under femtosecond pulsed excitation on trapping efficiency is investigated.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133985760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jtu4a.2
F. Pisano, Liam Collard, M. Kashif, Antonio Balena, M. Pisanello, Di Zheng, F. De Angelis, M. Grande, C. Ciracì, M. de Vittorio, F. Pisanello
We present a strategy to enhance the performances of optical neural implants using the interaction of light guided in multimode fibers with angle- and wavelength-dependent resonances supported by integrated plasmonic metasurfaces.
{"title":"Augmented optical neural implants using plasmonic nanomodulators integrated on multimode fibers","authors":"F. Pisano, Liam Collard, M. Kashif, Antonio Balena, M. Pisanello, Di Zheng, F. De Angelis, M. Grande, C. Ciracì, M. de Vittorio, F. Pisanello","doi":"10.1364/boda.2023.jtu4a.2","DOIUrl":"https://doi.org/10.1364/boda.2023.jtu4a.2","url":null,"abstract":"We present a strategy to enhance the performances of optical neural implants using the interaction of light guided in multimode fibers with angle- and wavelength-dependent resonances supported by integrated plasmonic metasurfaces.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131791909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dm4a.2
Siddra Maryam, Daniyal Ghauri, S. Sekar, E. Fahy, M. Nogueira, Huihui Lu, Flavien Beffara, Georges Humbert, R. Burke, L. Feeley, P. Sheahan, R. N. Ríordáin, S. Andersson-Engels, K. Kho, Rekha Gautam
This study aims to develop a multimodal scheme for diagnosing oral cancer non-invasively in its early stages and to assess the performance of an integrated diagnostic platform comprising of Raman and diffuse reflectance spectroscopy systems.
{"title":"Non-Invasive multimodal spectroscopic Diagnosis for Early-Stage Oral Cancer","authors":"Siddra Maryam, Daniyal Ghauri, S. Sekar, E. Fahy, M. Nogueira, Huihui Lu, Flavien Beffara, Georges Humbert, R. Burke, L. Feeley, P. Sheahan, R. N. Ríordáin, S. Andersson-Engels, K. Kho, Rekha Gautam","doi":"10.1364/boda.2023.dm4a.2","DOIUrl":"https://doi.org/10.1364/boda.2023.dm4a.2","url":null,"abstract":"This study aims to develop a multimodal scheme for diagnosing oral cancer non-invasively in its early stages and to assess the performance of an integrated diagnostic platform comprising of Raman and diffuse reflectance spectroscopy systems.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131864730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dw1a.5
V. Perekatova, A. Kostyuk, M. Kirillin, E. Sergeeva, D. Kurakina, Olga Shemagina, A. Orlova, A. Khilov, I. Turchin
A VIS-NIR experimental setup for diffuse reflectance spectroscopy with a fiber-optic probe employing a self-calibrating approach has been created and demonstrated high robustness to various instrumental perturbations in source and detector channels.
{"title":"Broadband diffuse reflectance spectroscopy system with a self-calibrating fiber-optic probe","authors":"V. Perekatova, A. Kostyuk, M. Kirillin, E. Sergeeva, D. Kurakina, Olga Shemagina, A. Orlova, A. Khilov, I. Turchin","doi":"10.1364/boda.2023.dw1a.5","DOIUrl":"https://doi.org/10.1364/boda.2023.dw1a.5","url":null,"abstract":"A VIS-NIR experimental setup for diffuse reflectance spectroscopy with a fiber-optic probe employing a self-calibrating approach has been created and demonstrated high robustness to various instrumental perturbations in source and detector channels.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113993407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jtu4b.8
S. H. Kim, Ludguier D. Montejo, A. Hielscher
This work focuses on the evaluation of frequency-domain 3rd-order simplified spherical harmonics (FD-SP3) model based image reconstruction with respect to its clinical utility to diagnose rheumatoid arthritis (RA). The results presented here show that the FD-SP3 model achieves clinically relevant sensitivity (88%) and specificity (93%) that compare favorably to the ERT while maintaining significant computational advantage over the ERT.
{"title":"Diagnostic Performance of the Frequency-Domain Third- Order Simplified Spherical Harmonics (SP3) Model on Rheumatoid Arthritis in Finger Joints","authors":"S. H. Kim, Ludguier D. Montejo, A. Hielscher","doi":"10.1364/boda.2023.jtu4b.8","DOIUrl":"https://doi.org/10.1364/boda.2023.jtu4b.8","url":null,"abstract":"This work focuses on the evaluation of frequency-domain 3rd-order simplified spherical harmonics (FD-SP3) model based image reconstruction with respect to its clinical utility to diagnose rheumatoid arthritis (RA). The results presented here show that the FD-SP3 model achieves clinically relevant sensitivity (88%) and specificity (93%) that compare favorably to the ERT while maintaining significant computational advantage over the ERT.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114417950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dw4a.4
Elizabeth Aguilar, E. Guevara, Guadalupe Donjuán-Loredo, R. Espinosa‐Tanguma, Roberto Salgado Delgado, M. Ramírez-Elías
Steatosis is when the liver accumulates more than 5% of its total weight in fat. Raman imaging was used to evaluate the molecular content of ex vivo rat liver tissue samples, where proteins and fatty acids were found in abundance.
{"title":"Analysis of Non-Alcoholic Fatty Liver Through Intensity Maps Applying Raman Spectroscopy","authors":"Elizabeth Aguilar, E. Guevara, Guadalupe Donjuán-Loredo, R. Espinosa‐Tanguma, Roberto Salgado Delgado, M. Ramírez-Elías","doi":"10.1364/boda.2023.dw4a.4","DOIUrl":"https://doi.org/10.1364/boda.2023.dw4a.4","url":null,"abstract":"Steatosis is when the liver accumulates more than 5% of its total weight in fat. Raman imaging was used to evaluate the molecular content of ex vivo rat liver tissue samples, where proteins and fatty acids were found in abundance.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123229051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dm2a.5
Z. Guang, Y. Reddy, S. Balakirsky, Konrad Ahlin, Francisco E. Robles
We develop an epi-mode quantitative phase imaging device to characterize cell structure and dynamic activity. It is composed of an optical imager using quantitative oblique back-illumination microscopy and a hyper redundant, high degree-of-freedom snake robot.
{"title":"Epi-Mode Quantitative Phase Imaging to Characterize Cell Structure and Dynamics with a Flexible Snake Robot","authors":"Z. Guang, Y. Reddy, S. Balakirsky, Konrad Ahlin, Francisco E. Robles","doi":"10.1364/boda.2023.dm2a.5","DOIUrl":"https://doi.org/10.1364/boda.2023.dm2a.5","url":null,"abstract":"We develop an epi-mode quantitative phase imaging device to characterize cell structure and dynamic activity. It is composed of an optical imager using quantitative oblique back-illumination microscopy and a hyper redundant, high degree-of-freedom snake robot.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121806214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jw2b.3
Meimei Lai, Erem Ujah, G. Slaughter
Tapered optical fiber (TOF) was successfully fabricated for refractive index glucose sensing. AuNPs decorated TOF introduced localized surface plasmon resonance. Optical transmission with an ultralow-power beam showed AuNPs enhanced the sensitivity by 4 times (2032%/RIU).
{"title":"Ultralow Power Refractive Index Tapered Optical Fiber Glucose Sensor","authors":"Meimei Lai, Erem Ujah, G. Slaughter","doi":"10.1364/boda.2023.jw2b.3","DOIUrl":"https://doi.org/10.1364/boda.2023.jw2b.3","url":null,"abstract":"Tapered optical fiber (TOF) was successfully fabricated for refractive index glucose sensing. AuNPs decorated TOF introduced localized surface plasmon resonance. Optical transmission with an ultralow-power beam showed AuNPs enhanced the sensitivity by 4 times (2032%/RIU).","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"152 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124232335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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