Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dw3a.3
A. S, Nirmalya Ghosh, N. Le, Ruikang K Wang
We propose a scheme for polarization sensitive measurements with fiber based optical coherence tomography based on the nonreciprocal behavior of Faraday rotator to measure the 3 X 3 Mueller matrix of the sample.
{"title":"Mueller matrix measurement using Faraday rotator-based fiber polarization sensitive optical coherence tomography","authors":"A. S, Nirmalya Ghosh, N. Le, Ruikang K Wang","doi":"10.1364/boda.2023.dw3a.3","DOIUrl":"https://doi.org/10.1364/boda.2023.dw3a.3","url":null,"abstract":"We propose a scheme for polarization sensitive measurements with fiber based optical coherence tomography based on the nonreciprocal behavior of Faraday rotator to measure the 3 X 3 Mueller matrix of the sample.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114691558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jtu4b.30
I. Kosik, R. Weersink, S. Ghai, Andrew Effat, Theo Husby, Brian Wilson
We present deep tissue (> 2 cm), widefield (5 cm x 5cm) real-time (10 Hz) photoacoustic thermometry in ex-vivo tissue phantoms as well as first in-patient diffuse optical monitoring of photothermal therapy for prostate cancer.
{"title":"A Photothermal Therapy Guidance System with Photoacoustic Thermometry and Diffuse Optical Tomography","authors":"I. Kosik, R. Weersink, S. Ghai, Andrew Effat, Theo Husby, Brian Wilson","doi":"10.1364/boda.2023.jtu4b.30","DOIUrl":"https://doi.org/10.1364/boda.2023.jtu4b.30","url":null,"abstract":"We present deep tissue (> 2 cm), widefield (5 cm x 5cm) real-time (10 Hz) photoacoustic thermometry in ex-vivo tissue phantoms as well as first in-patient diffuse optical monitoring of photothermal therapy for prostate cancer.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114711342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.jtu4b.11
Stephani Edwina Lucia, Jehwi Jeon, Jieun Choi, Pilhan Kim
Longitudinal cellular-level imaging of pancreatic tumor microenvironment at the same site in the pancreas of preclinical mouse model was achieved by using intravital dual-mode two- photon and confocal microscope combined with pancreas imaging window.
{"title":"Intravital Longitudinal Visualization of Pancreatic Ductal Adenocarcinoma Tumor Microenvironment","authors":"Stephani Edwina Lucia, Jehwi Jeon, Jieun Choi, Pilhan Kim","doi":"10.1364/boda.2023.jtu4b.11","DOIUrl":"https://doi.org/10.1364/boda.2023.jtu4b.11","url":null,"abstract":"Longitudinal cellular-level imaging of pancreatic tumor microenvironment at the same site in the pancreas of preclinical mouse model was achieved by using intravital dual-mode two- photon and confocal microscope combined with pancreas imaging window.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126288775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/brain.2023.bw3b.6
B. Rózsa, Z. Szadai, L. Judák, B. Chiovini, G. Juhász, Katalin Ócsai, D. Pálfi, Zsolt Mezriczky, Gergely Szalay, G. Katona, Anna Mihály, Áron Szepesi, Z. Mucsi, B. Roska, H. Pi, Quentin Chevy, Florin Albeanu, Adam Kepecs
Acousto-optical microscopy is a powerful tool to study spare networks and extensive dendritic arborization from the cortex of behaving animals. We used this novel approach for imaging dendrites and somata of sparse interneuron populations in a combination with auditory discrimination and detection tasks. Our results shed light of not yet known subcellular and network mechanisms from multiple brain regions.
{"title":"Imaging of dendrites and sparse interneuronal networks with 3D random access microscopy","authors":"B. Rózsa, Z. Szadai, L. Judák, B. Chiovini, G. Juhász, Katalin Ócsai, D. Pálfi, Zsolt Mezriczky, Gergely Szalay, G. Katona, Anna Mihály, Áron Szepesi, Z. Mucsi, B. Roska, H. Pi, Quentin Chevy, Florin Albeanu, Adam Kepecs","doi":"10.1364/brain.2023.bw3b.6","DOIUrl":"https://doi.org/10.1364/brain.2023.bw3b.6","url":null,"abstract":"Acousto-optical microscopy is a powerful tool to study spare networks and extensive dendritic arborization from the cortex of behaving animals. We used this novel approach for imaging dendrites and somata of sparse interneuron populations in a combination with auditory discrimination and detection tasks. Our results shed light of not yet known subcellular and network mechanisms from multiple brain regions.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126475536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riley J. Deutsch, Roujia Wang, Enakshi D Sunassee, Megan C. Madonna, B. Crouch, N. Ramanujam
We developed an approach to quantify intratumoral metabolic heterogeneity of in vivo tumor models by leveraging a computationally designed multi-scale microscope and a suite of exogenous fluorescent contrast agents to provide functional and structural information.
{"title":"Development of a multi-scale platform to quantify metabolic heterogeneity in vivo","authors":"Riley J. Deutsch, Roujia Wang, Enakshi D Sunassee, Megan C. Madonna, B. Crouch, N. Ramanujam","doi":"10.1364/omp.2023.ow1e.3","DOIUrl":"https://doi.org/10.1364/omp.2023.ow1e.3","url":null,"abstract":"We developed an approach to quantify intratumoral metabolic heterogeneity of in vivo tumor models by leveraging a computationally designed multi-scale microscope and a suite of exogenous fluorescent contrast agents to provide functional and structural information.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131515634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/oma.2023.atu1d.4
Chenglong Zhao, Geonsoo Jin, T. Huang
Optical imaging with nanoscale resolution and a large field of view are highly desirable optical imaging. This talk introduces an acoustofluidic scanning nanoscope that can achieve both super-resolution and large field-of-view imaging.
{"title":"Acoustofluidic Scanning Nanoscope for Large Field-of-view Imaging","authors":"Chenglong Zhao, Geonsoo Jin, T. Huang","doi":"10.1364/oma.2023.atu1d.4","DOIUrl":"https://doi.org/10.1364/oma.2023.atu1d.4","url":null,"abstract":"Optical imaging with nanoscale resolution and a large field of view are highly desirable optical imaging. This talk introduces an acoustofluidic scanning nanoscope that can achieve both super-resolution and large field-of-view imaging.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133513582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dw4a.7
Dibbyan Mazumder, Oybek Kholiqov, V. Srinivasan
We demonstrate an interferometric near-infrared spectroscopy (iNIRS) instrument, operating simultaneously at two wavelengths, for quantification of optical properties of turbid media. Measurements are demonstrated on a fluid phantom.
{"title":"Dual-wavelength interferometric near-infrared spectroscopy (iNIRS)","authors":"Dibbyan Mazumder, Oybek Kholiqov, V. Srinivasan","doi":"10.1364/boda.2023.dw4a.7","DOIUrl":"https://doi.org/10.1364/boda.2023.dw4a.7","url":null,"abstract":"We demonstrate an interferometric near-infrared spectroscopy (iNIRS) instrument, operating simultaneously at two wavelengths, for quantification of optical properties of turbid media. Measurements are demonstrated on a fluid phantom.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133519423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dtu3a.3
Aidan M. Therien, Jingpeng Hu, Shuyang Fang, K. Myers, C. Hendon
High resolution collagen fiber organization is a prime metric for evaluating uterine health. In this research, computational methods for collagen fiber orientation analysis of registered and stitched ultra-large OCT uterine volumes were developed.
{"title":"Deep Learning enabled comprehensive tissue architecture and fiber analysis of the human uterus","authors":"Aidan M. Therien, Jingpeng Hu, Shuyang Fang, K. Myers, C. Hendon","doi":"10.1364/boda.2023.dtu3a.3","DOIUrl":"https://doi.org/10.1364/boda.2023.dtu3a.3","url":null,"abstract":"High resolution collagen fiber organization is a prime metric for evaluating uterine health. In this research, computational methods for collagen fiber orientation analysis of registered and stitched ultra-large OCT uterine volumes were developed.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133457164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1364/boda.2023.dth2c.4
Alexis Coullomb, Peter T. Brown, D. Shepherd
A new spot decoding method allows to infer at scale and more accurately mRNA species from 3D spots localized with a physics-based approach in big datasets of barcoded RNA-FISH experiments.
{"title":"Localization-based spot decoding for accurate multiplexed RNA-FISH at scale","authors":"Alexis Coullomb, Peter T. Brown, D. Shepherd","doi":"10.1364/boda.2023.dth2c.4","DOIUrl":"https://doi.org/10.1364/boda.2023.dth2c.4","url":null,"abstract":"A new spot decoding method allows to infer at scale and more accurately mRNA species from 3D spots localized with a physics-based approach in big datasets of barcoded RNA-FISH experiments.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133470076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We have developed a laser speckle imaging method based on selected plane illumination. Optical sectioning is achieved for 3D quantitative flow imaging.
本文提出了一种基于选定平面照明的激光散斑成像方法。光学切片实现了三维定量流成像。
{"title":"Laser speckle imaging with tilted plane illumination","authors":"Kai Long, Shuhao Shen, E. Du, Nanguang Chen","doi":"10.1364/ntm.2023.nw3c.3","DOIUrl":"https://doi.org/10.1364/ntm.2023.nw3c.3","url":null,"abstract":"We have developed a laser speckle imaging method based on selected plane illumination. Optical sectioning is achieved for 3D quantitative flow imaging.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131319027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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