Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100982
Tao Xiong, Yuxi Wang, Xuan Zhang, Xiangling Wang, Hong Zhang, Weiqun Cao, Yi Tao, Liang Shen, Genfu Chen
{"title":"Establishment and characterization of an in vitro model for NTCP substrate and inhibition assessment","authors":"Tao Xiong, Yuxi Wang, Xuan Zhang, Xiangling Wang, Hong Zhang, Weiqun Cao, Yi Tao, Liang Shen, Genfu Chen","doi":"10.1016/j.dmpk.2023.100982","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100982","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100975
Bhargavi Srija Ramisetty, Sihyung Yang, Michael Zhuo Wang
{"title":"Physiologically based pharmacokinetic model for miltefosine in mice","authors":"Bhargavi Srija Ramisetty, Sihyung Yang, Michael Zhuo Wang","doi":"10.1016/j.dmpk.2023.100975","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100975","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100948
Xiangling Wang, Haijuan Liu, Yilin Wei, Jie Wang, Nan Zhao, Yi Tao, Liang Shen, Genfu Chen
{"title":"Development of plasma stability assay for oligonucleotides","authors":"Xiangling Wang, Haijuan Liu, Yilin Wei, Jie Wang, Nan Zhao, Yi Tao, Liang Shen, Genfu Chen","doi":"10.1016/j.dmpk.2023.100948","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100948","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100961
Shugo Yamashita, Shunsuke Kimura, Akiko Kiriyama
{"title":"An approach using a gamma-distributed delay model to evaluate the anticancer effect of doxorubicin-encapsulated polymeric micelles by predictive pharmacokinetic-pharmacodynamic modeling","authors":"Shugo Yamashita, Shunsuke Kimura, Akiko Kiriyama","doi":"10.1016/j.dmpk.2023.100961","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100961","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100963
Jessica Rehmel, Maria Posada
{"title":"Verification of a physiologically based pharmacokinetic model of caffeine that incorporates mechanistic descriptors of absorption","authors":"Jessica Rehmel, Maria Posada","doi":"10.1016/j.dmpk.2023.100963","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100963","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100935
Mario Oeren, Peter Walton, Sylvia Kaempf, James Suri, David Ponting, Peter Hunt, Tamsin Mansley, Matthew Segall
{"title":"From quantum mechanics to metabolism pathways","authors":"Mario Oeren, Peter Walton, Sylvia Kaempf, James Suri, David Ponting, Peter Hunt, Tamsin Mansley, Matthew Segall","doi":"10.1016/j.dmpk.2023.100935","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100935","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100958
Gianna Ferron, Stefan Linehan, Tim Ragan, Dylan Garceau, Kevin Elk, Mike Sasner
{"title":"A novel 3D imaging pipeline for analyzing efficacy of compounds on amyloid-beta plaque dynamics in preclinical alzheimer’s disease animal models","authors":"Gianna Ferron, Stefan Linehan, Tim Ragan, Dylan Garceau, Kevin Elk, Mike Sasner","doi":"10.1016/j.dmpk.2023.100958","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100958","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141064212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100964
Yifan Gong, Ken Korzekwa, Swati Nagar
{"title":"Evaluating the impact of glycocalyx on partitioning and distribution of basic drugs","authors":"Yifan Gong, Ken Korzekwa, Swati Nagar","doi":"10.1016/j.dmpk.2023.100964","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100964","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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