Titrimetric methods for determining the concentration of quaternary ammonium salts and polyhexamethylenebiguanide hydrochloride in the presence of a disinfectant are described. In addition, as auxiliary components, the agent contains a nonionic surfactant and an alkyl polyglucoside and a disodium salt of ethylenediaminetetraacetic acid as a complexing agent. The main differences between the methods proposed by us for the determination of quaternary ammonium salts and polyhexamethylenebiguanide hydrochloride is the use of not sodium dodecyl sulfate as a titrant, but a solution of the disinfectant itself, which greatly facilitated the visual fixation of the equivalence point. In addition, the volume of the indicator (methylene blue and bromophenol blue) was selected in such a way that the exposure between the portions of the added titrant was not prolonged, because this would increase the overall duration of the analysis. When titrating with polyhexamethylenebiguanide hydrochloride, the volume of the indicator is selected in such a way as to minimize the interfering effect of HR, which are also part of disinfectants. The reproducibility of the developed methods has been confirmed in accredited laboratories of the relevant state institutions of the Republic of Belarus. Metrological characteristics of the developed methods: accuracy index±3.7 %, reproducibility index 4.0 %, n = 17, P = 0.95 – to determine the QAS; accuracy index±4.2 %, reproducibility index 5.5 %, n = 17, P = 0.95 – for the determination of PHMBG.
描述了在消毒剂存在下测定季铵盐和聚己二胍盐酸盐浓度的滴定法。此外，作为辅助组分，该剂含有非离子表面活性剂和烷基聚葡萄糖苷和乙二胺四乙酸二钠盐作为络合剂。我们所提出的测定季铵盐和聚六亚甲基二胍盐酸盐的方法的主要区别在于，不是使用十二烷基硫酸钠作为滴定剂，而是使用消毒剂本身的溶液，这大大方便了等当点的视觉固定。此外，指示剂(亚甲基蓝和溴酚蓝)的体积选择时，添加的滴定剂部分之间的暴露时间不会延长，因为这会增加分析的总体持续时间。用盐酸聚六亚二胍滴定时，指示剂的体积选择应尽量减少HR的干扰作用，HR也是消毒剂的一部分。所开发方法的可重复性已在白俄罗斯共和国有关国家机构的认可实验室中得到证实。所建立方法的计量特性:准确度指数为±3.7%，重现性指数为4.0%，n = 17, P = 0.95 -测定QAS;准确度为±4.2%，重现性为5.5%，n = 17, P = 0.95。
{"title":"Determination of quaternary ammonium salts and polyhexamethylene biguanide hydrochloride in the coexistence in disinfectants and their biocidal activity","authors":"Yuliya Vladimirovna Matveichuk, Llc «Nordkhim», Dmitrii Vladislavovich Stanishevsky, Yu. V. Shabeka","doi":"10.35411/2076-457x-2021-2-5-10","DOIUrl":"https://doi.org/10.35411/2076-457x-2021-2-5-10","url":null,"abstract":"Titrimetric methods for determining the concentration of quaternary ammonium salts and polyhexamethylenebiguanide hydrochloride in the presence of a disinfectant are described. In addition, as auxiliary components, the agent contains a nonionic surfactant and an alkyl polyglucoside and a disodium salt of ethylenediaminetetraacetic acid as a complexing agent. The main differences between the methods proposed by us for the determination of quaternary ammonium salts and polyhexamethylenebiguanide hydrochloride is the use of not sodium dodecyl sulfate as a titrant, but a solution of the disinfectant itself, which greatly facilitated the visual fixation of the equivalence point. In addition, the volume of the indicator (methylene blue and bromophenol blue) was selected in such a way that the exposure between the portions of the added titrant was not prolonged, because this would increase the overall duration of the analysis. When titrating with polyhexamethylenebiguanide hydrochloride, the volume of the indicator is selected in such a way as to minimize the interfering effect of HR, which are also part of disinfectants. The reproducibility of the developed methods has been confirmed in accredited laboratories of the relevant state institutions of the Republic of Belarus. Metrological characteristics of the developed methods: accuracy index±3.7 %, reproducibility index 4.0 %, n = 17, P = 0.95 – to determine the QAS; accuracy index±4.2 %, reproducibility index 5.5 %, n = 17, P = 0.95 – for the determination of PHMBG.","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78876527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.35411/2076-457x-2021-2-30-36
T. A. Davlianidze
Knockdown resistance to pyrethroids and pyrethrins is the first sign of insecticide resistance, suggesting a decrease in insect nervous system sensitivity. On the Russian market of insecticides, there are many products in the aerosol package intended for the destruction of flying insects, which include pyrethroids, which provide a quick knockdown effect in insecticide susceptible insect strains. In resistant populations, in many cases, the reversibility of paralysis is observed, which indicates insufficient effectiveness of insecticidal products. The insecticidal activity of four products in aerosol package containing pyrethroids or pyrethrins in various concentrations on houseflies in natural populations was studied in comparison with the insecticide susceptible against laboratory on strain S-NIID. The most effective formulation was on the basis of natural pyrethrins. The reversibility of paralysis of resistant populations was detected using all aerosols and amounted to 0–37 % for the Kaluga strain, 10–93 % for the Krasnogorsk, KSK-1 0–87 %, KSK-2 20–99 %, S-NIID 0 %.
{"title":"Reversibility of the knockdown effect at application of aerosols against pyrethroid-resistant house flies","authors":"T. A. Davlianidze","doi":"10.35411/2076-457x-2021-2-30-36","DOIUrl":"https://doi.org/10.35411/2076-457x-2021-2-30-36","url":null,"abstract":"Knockdown resistance to pyrethroids and pyrethrins is the first sign of insecticide resistance, suggesting a decrease in insect nervous system sensitivity. On the Russian market of insecticides, there are many products in the aerosol package intended for the destruction of flying insects, which include pyrethroids, which provide a quick knockdown effect in insecticide susceptible insect strains. In resistant populations, in many cases, the reversibility of paralysis is observed, which indicates insufficient effectiveness of insecticidal products. The insecticidal activity of four products in aerosol package containing pyrethroids or pyrethrins in various concentrations on houseflies in natural populations was studied in comparison with the insecticide susceptible against laboratory on strain S-NIID. The most effective formulation was on the basis of natural pyrethrins. The reversibility of paralysis of resistant populations was detected using all aerosols and amounted to 0–37 % for the Kaluga strain, 10–93 % for the Krasnogorsk, KSK-1 0–87 %, KSK-2 20–99 %, S-NIID 0 %.","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88642591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.35411/2076-457x-2021-2-10-15
M. V. Bidevkina, Tatyana Nikolaevna Potapova, M. V. Matrosenko
InVitro laboratory has investigated and made comparative analysis of irritant effect of disinfectants on rabbits. Main active substances of studied skin antiseptics were: alcohols, chlorhexidine bigluconate, alkyldimethylbenzylammonium chloride, didecyldimethylammonium chloride, N,N-bis(3-aminopropyl)dodecylamine. Has been developed method for evaluating the irritant effect of skin antiseptics on bull sperm suspensions.
{"title":"Assessment of the safety of skin antiseptics by the method of in vitro","authors":"M. V. Bidevkina, Tatyana Nikolaevna Potapova, M. V. Matrosenko","doi":"10.35411/2076-457x-2021-2-10-15","DOIUrl":"https://doi.org/10.35411/2076-457x-2021-2-10-15","url":null,"abstract":"InVitro laboratory has investigated and made comparative analysis of irritant effect of disinfectants on rabbits. Main active substances of studied skin antiseptics were: alcohols, chlorhexidine bigluconate, alkyldimethylbenzylammonium chloride, didecyldimethylammonium chloride, N,N-bis(3-aminopropyl)dodecylamine. Has been developed method for evaluating the irritant effect of skin antiseptics on bull sperm suspensions.","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87037625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.35411/2076-457x-2021-2-15-22
O. Eremina, V. V. Olifer
Comparative efficacy of neonicotinoid-based baits (thiamethoxam, imidacloprid, acetamiprid) intended for control of the Pharaoh ant was studied. The death of workers, queens and brood occurs within 2–4 weeks. The minimum effective concentrations of thiamethoxam and imidacloprid in granulated sugar, which ensure the death of ant colonies in the presence and absence of an alternative food, were revealed. Under laboratory conditions, when the colonies of the Pharaoh ant were fed with such baits, after 4 weeks of the experiment the depletion of the colony was noted (death of queens was 75–100 %, and critical decrease in the number of live workers and brood was occured). Dry sugar baits based on 0.1–1.0 % acetamiprid have no significant effect on the viability of the ant colony.
{"title":"The study of neonicotinoids baits on susceptible laboratory culture of pharaoh ants","authors":"O. Eremina, V. V. Olifer","doi":"10.35411/2076-457x-2021-2-15-22","DOIUrl":"https://doi.org/10.35411/2076-457x-2021-2-15-22","url":null,"abstract":"Comparative efficacy of neonicotinoid-based baits (thiamethoxam, imidacloprid, acetamiprid) intended for control of the Pharaoh ant was studied. The death of workers, queens and brood occurs within 2–4 weeks. The minimum effective concentrations of thiamethoxam and imidacloprid in granulated sugar, which ensure the death of ant colonies in the presence and absence of an alternative food, were revealed. Under laboratory conditions, when the colonies of the Pharaoh ant were fed with such baits, after 4 weeks of the experiment the depletion of the colony was noted (death of queens was 75–100 %, and critical decrease in the number of live workers and brood was occured). Dry sugar baits based on 0.1–1.0 % acetamiprid have no significant effect on the viability of the ant colony.","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87294069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.35411/2076-457x-2021-2-36-43
S. A. Roslavtseva, A. I. Frolova, M. A. Alekseev
Literature on distribution of invasive mosquito species that are vectors of especially dangerous infections (dengue, Chikungunya, Zika, yellow fever, and Japanese encephalitis) in the Europe and Russia was briefly reviewed. Global warming of the climate as well as an increase in the volume of world trade and the biological characteristics of mosquitoes contribute to the widespread of these species on territories of many countries and continents
{"title":"New data on distribution of invasive mosquito species in the Europe and in Russia","authors":"S. A. Roslavtseva, A. I. Frolova, M. A. Alekseev","doi":"10.35411/2076-457x-2021-2-36-43","DOIUrl":"https://doi.org/10.35411/2076-457x-2021-2-36-43","url":null,"abstract":"Literature on distribution of invasive mosquito species that are vectors of especially dangerous infections (dengue, Chikungunya, Zika, yellow fever, and Japanese encephalitis) in the Europe and Russia was briefly reviewed. Global warming of the climate as well as an increase in the volume of world trade and the biological characteristics of mosquitoes contribute to the widespread of these species on territories of many countries and continents","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81549046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-01DOI: 10.35411/2076-457x-2020-2-69-74
V. A. Tsurkan
{"title":"Clinical and epidemiological aspects of driving and dissemination of tuberculosis infection in psychiatric hospitals","authors":"V. A. Tsurkan","doi":"10.35411/2076-457x-2020-2-69-74","DOIUrl":"https://doi.org/10.35411/2076-457x-2020-2-69-74","url":null,"abstract":"","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85368557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resistance of non-tuberculosis mycobacteria to chemical and physical means of disinfection (literature review)Оценка устойчивости нетуберкулёзных микобактерий к дезинфицирующим средствам: обзор эпидемиологических исследованийState Research Center of Applied Microbiology and Biotechnology of Rospotre","authors":"Tanzilya Khafizovna Amirova, Ilya Vladimirovich Petrov, L. Petrova, Firuza Salavatovna Petrova","doi":"10.35411/2076-457x-2020-2-5-16","DOIUrl":"https://doi.org/10.35411/2076-457x-2020-2-5-16","url":null,"abstract":"","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80494733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-01DOI: 10.35411/2076-457x-2020-2-63-69
V. P. Popov, Nadezhda Aleksandrovna Malitskaya, S. V. Ryabov
{"title":"Natural centers of tularemia of Sakhalin region","authors":"V. P. Popov, Nadezhda Aleksandrovna Malitskaya, S. V. Ryabov","doi":"10.35411/2076-457x-2020-2-63-69","DOIUrl":"https://doi.org/10.35411/2076-457x-2020-2-63-69","url":null,"abstract":"","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80590243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-01DOI: 10.35411/2076-457x-2020-2-56-62
N.M. Ermakov, A. Matrosov
{"title":"Approbation of Devices for Disinsection of Burrows of Small Mammals in the Gorno-Altai High-Mountain Natural Plague Focus","authors":"N.M. Ermakov, A. Matrosov","doi":"10.35411/2076-457x-2020-2-56-62","DOIUrl":"https://doi.org/10.35411/2076-457x-2020-2-56-62","url":null,"abstract":"","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88014549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-27DOI: 10.35411/2076-457x-2019-3-60-68
Anastasia V. Ilyakova, N. Shestopalov, L. Fedorova
{"title":"The collection of microorganisms cultures at the Scientic Research Disinfectology Institute","authors":"Anastasia V. Ilyakova, N. Shestopalov, L. Fedorova","doi":"10.35411/2076-457x-2019-3-60-68","DOIUrl":"https://doi.org/10.35411/2076-457x-2019-3-60-68","url":null,"abstract":"","PeriodicalId":11317,"journal":{"name":"Disinfection affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73408343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：