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Disc-Oedema Toxoplasmosis. 椎间盘水肿弓形虫病。
IF 0.8 Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI: 10.1080/01658107.2023.2242969
Parthopratim Dutta Majumder, Jyotirmay Biswas
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引用次数: 0
We'll never have a model of an AI major-general: Artificial Intelligence, command decisions, and kitsch visions of war. 我们永远不会有人工智能少将的模型:人工智能、指挥决策,以及对战争的俗套想象。
IF 1.9 Pub Date : 2023-08-07 eCollection Date: 2024-01-01 DOI: 10.1080/01402390.2023.2241648
Cameron Hunter, Bleddyn E Bowen

Military AI optimists predict future AI assisting or making command decisions. We instead argue that, at a fundamental level, these predictions are dangerously wrong. The nature of war demands decisions based on abductive logic, whilst machine learning (or 'narrow AI') relies on inductive logic. The two forms of logic are not interchangeable, and therefore AI's limited utility in command - both tactical and strategic - is not something that can be solved by more data or more computing power. Many defence and government leaders are therefore proceeding with a false view of the nature of AI and of war itself.

军事人工智能乐观主义者预测未来人工智能将协助或做出指挥决策。而我们认为,从根本上讲,这些预测都是危险的错误。战争的本质要求基于归纳逻辑做出决策,而机器学习(或 "狭义人工智能")则依赖于归纳逻辑。这两种逻辑形式不能互换,因此,人工智能在战术和战略指挥方面的作用有限,这不是更多数据或更强计算能力就能解决的问题。因此,许多国防和政府领导人对人工智能和战争本身的性质持有错误的看法。
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引用次数: 0
Microbial Biocatalysis within Us: The Underexplored Xenobiotic Biotransformation Potential of the Urinary Tract Microbiota. 我们体内的微生物生物催化:泌尿道微生物群未被充分开发的异种生物转化潜力。
IF 1.2 Pub Date : 2023-06-28 DOI: 10.2533/chimia.2023.424
Thierry D Marti, Milo R Schärer, Serina L Robinson

Enzymatic biotransformation of xenobiotics by the human microbiota mediates diet-drug-microbe-host interactions and affects human health. Most research on xenobiotics has focused on the gut microbiota while neglecting other body sites, yet over two-thirds of pharmaceuticals are primarily excreted in urine. As a result, the urinary microbiota is exposed to many xenobiotics in much higher concentrations than in the gut. Microbial xenobiotic biocatalysis in the bladder has implications for urinary tract infections and the emergence of antibiotic resistance. However, we have limited knowledge of biotransformations catalyzed by the urinary microbiota. In this perspective, we investigated differences in physicochemical conditions and microbial community composition between the gut and urinary tract. We used a comparative enzyme class mining approach to profile the distribution of xenobiotic-transforming enzyme homologs in genomes of urinary bacteria. Our analysis revealed a discontinuous distribution of enzyme classes even among closely related organisms. We detected diverse amidase homologs involved in pharmaceutical and dietary additive biotransformation pathways, pinpointing microbial candidates to validate for their involvement in xenobiotic transformations in urine. Overall, we highlight the biocatalytic potential of urinary tract bacteria as a lens to study how the human microbiota may respond and adapt to xenobiotic inputs.

人类微生物群对异种生物的酶促生物转化介导饮食-药物-微生物-宿主相互作用并影响人类健康。大多数关于外源药物的研究都集中在肠道微生物群上,而忽略了身体的其他部位,然而超过三分之二的药物主要通过尿液排出。因此,尿液微生物群暴露于许多浓度比肠道高得多的异种抗生素中。膀胱内的微生物异种生物催化对尿路感染和抗生素耐药性的出现有影响。然而,我们对尿液微生物群催化的生物转化的知识有限。从这个角度来看,我们研究了肠道和泌尿道之间的理化条件和微生物群落组成的差异。我们使用比较酶类挖掘方法来分析泌尿细菌基因组中异种转化酶同源物的分布。我们的分析显示,即使在密切相关的生物体中,酶类的分布也是不连续的。我们检测了参与药物和膳食添加剂生物转化途径的多种酰胺酶同源物,确定了微生物候选物,以验证它们参与尿液中的异种转化。总的来说,我们强调了尿路细菌的生物催化潜力,作为研究人类微生物群如何响应和适应外来生物输入的透镜。
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引用次数: 0
Preface 前言
Pub Date : 2023-04-28 DOI: 10.1051/e3sconf/202339700001
N. Novitsky, B. Serttter, V. R. Chupin, E. Khaltar, L. Korelstein, V. A. Stennikov, M. Sukharev
Euro Asia Civil Engineering Forum (EACEF) was founded in 2006 in Stuttgart – Germany. The founders of EACEF are Prof. Dr.-Ing. Harianto Hardjasaputra, Professor of Pembangunan Jaya University – Indonesia, and Prof. Dr.-Ing. Karl-Heinz Reineck, Senior Lecturer of the University of Stuttgart-Germany. Both would like to further their many years of cooperation with their international colleagues (especially those from Europe and Asia) through EACEF. EACEF is a forum to promote cooperation and understanding between European and Asian countries, focusing on Civil Engineering expertise. EACEF will play an essential role as the bridge between these two continents in linking European and Asian Civil Engineers, especially those committed to sustainable development and environmentally friendly buildings. The conference has been conducted biannually since 2007 in Jakarta, Indonesia, and has been conducted in several countries as well. The details of previous conferences can be found at https://eacef.com/. As the biannual conference, the 8th EACEF conference should be conducted in September 2021. However, due to the COVID-19 pandemic, the EACEF committee decided to postpone the 8th EACEF conference to October 2022. This Proceeding contains papers based on invited keynote speeches and oral presentations at the 8th EACEF conference 2022 “Advanced and Innovative Technology for Sustainable Infrastructure”. The event was held on October 4th-5th 2022 at OST Eastern Switzerland University of Applied Sciences, Switzerland and on October 12th-13th at University of Atma Jaya Yogyakarta, Indonesia. The event covered several topics: “Structural Engineering”, “Construction Material”, “Construction Management”, “Infrastructure Engineering”, and “Geotechnical Engineering”. The conference started with plenary sessions of keynote speakers on October 4th-5th 2022 (online presentation) and followed by technical sessions on October 12th-13th 2022 (hybrid presentation) which were divided into three parallel sessions. Each keynote speech took 30 minutes for presentation and discussion while speakers in technical sessions were given 10 minutes and 5 minutes for presentation and discussion, respectively. There was a total of 13 keynote speakers and 64 presenters which consist of both academicians and professionals from Indonesia as well as other countries such as China, Germany, Japan, Switzerland, Morocco, United States of America, Malaysia, Brunei Darussalam, United Kingdom, and Australia. Zoom video conferencing application was used in the event which served the event very well. Finally, please allow us to thank all participants in the 8th EACEF conference 2022. We hope that the conference is beneficial in sharing advanced knowledge in the field of Civil Engineering. We would also like to thank our colleagues who have organized the conference. Indeed, it was a successful conference. Last but not least, we also would like to express our gratitude for the sponsors that have supp
欧亚土木工程论坛(EACEF)于2006年在德国斯图加特成立。中华教育促进会的创始人是英博士教授。Harianto Hardjasaputra,印尼彭邦古南贾亚大学教授。Karl-Heinz Reineck,德国斯图加特大学高级讲师。双方都希望通过EACEF与国际同行(特别是来自欧洲和亚洲的同行)进一步深化多年的合作。EACEF是一个促进欧洲和亚洲国家之间的合作和理解的论坛,专注于土木工程专业知识。EACEF将在这两个大洲之间发挥重要的桥梁作用,将欧洲和亚洲的土木工程师,特别是那些致力于可持续发展和环保建筑的土木工程师联系起来。自2007年以来,该会议每两年在印度尼西亚雅加达举行一次,并在几个国家举行。以前会议的详细信息可在https://eacef.com/上找到。作为两年一度的会议,第八届会议将于2021年9月举行。但是,由于新冠肺炎疫情,EACEF委员会决定将第八届EACEF会议推迟到2022年10月举行。本论文集收录了2022年第八届EACEF会议“可持续基础设施的先进和创新技术”的受邀主题演讲和口头报告。该活动于2022年10月4日至5日在瑞士OST东瑞士应用科学大学和10月12日至13日在印度尼西亚的Atma Jaya日惹大学举行。会议涵盖了多个主题:“结构工程”、“建筑材料”、“施工管理”、“基础设施工程”和“岩土工程”。会议从2022年10月4日至5日的主题演讲全体会议(在线演讲)开始,随后是2022年10月12日至13日的技术会议(混合演讲),分为三个平行会议。主题演讲的发言和讨论时间为30分钟,技术发言的发言和讨论时间分别为10分钟和5分钟。会议共有13位主讲人和64位演讲人,其中包括来自印度尼西亚以及中国、德国、日本、瑞士、摩洛哥、美利坚合众国、马来西亚、文莱达鲁萨兰国、联合王国和澳大利亚等其他国家的院士和专业人士。本次活动中使用了Zoom视频会议应用,很好的服务了本次活动。最后,请允许我们感谢参加2022年第八届东亚经济论坛会议的所有与会者。我们希望这次会议对分享土木工程领域的先进知识是有益的。我们还要感谢组织这次会议的同事们。的确,这是一次成功的会议。最后但并非最不重要的是,我们还要对支持这次会议的赞助者表示感谢。EACEF 2022编辑名单、主讲人名单、指导委员会名单、国际科学委员会名单、组织委员会名单见此pdf。
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引用次数: 0
Accuracy and Utility of Internet Image Search as a Learning Tool for Retinal Pathology. 将互联网图像搜索作为视网膜病理学学习工具的准确性和实用性。
Pub Date : 2023-04-12 eCollection Date: 2023-01-01 DOI: 10.1055/s-0043-1768025
Lucy V Cobbs, Hytham Al-Hindi, Cherie Fathy, Raziyeh Mahmoudzadeh, Tara Uhler, David Xu

Purpose  Ophthalmology residency training heavily relies on visual and pattern recognition-based learning. In parallel with traditional reference texts, online internet search via Google Image Search (GIS) is commonly used and offers an accessible fund of reference images for ophthalmology trainees seeking rapid exposure to images of retinal pathology. However, the accuracy and quality of this tool within this context is unknown. We aim to evaluate the accuracy and quality of GIS images of selected retinal pathologies. Methods  A cross-sectional study was performed of GIS of 15 common and 15 rare retinal diseases drawn from the American Academy of Ophthalmology residency textbook series. A total of 300 evaluable image results were assessed for accuracy of images and image source accountability in consultation with a vitreoretinal surgeon. Results  A total of 377 images were reviewed with 77 excluded prior to final analysis. A total of 288 (96%) search results accurately portrayed the retinal disease being searched, whereas 12 (4%) were of an erroneous diagnosis. More images of common retinal diseases were from patient education Web sites than were images of rare diseases ( p  < 0.01). Significantly more images of rare retinal diseases were found in peer-reviewed sources ( p  = 0.01). Conclusions  GIS search results yielded a modest level of accuracy for the purposes of ophthalmic education. Despite the ease and rapidity of accessing multimodal retinal imaging examples, this tool may best be suited as a supplementary resource for learning among residents due to limited accuracy, lack of sufficient supporting information, and the source Web site's focus on patient education.

目的 眼科住院医师培训在很大程度上依赖于以视觉和模式识别为基础的学习。在使用传统参考文献的同时,通过谷歌图像搜索(GIS)进行的在线互联网搜索也被广泛使用,这为寻求快速接触视网膜病理学图像的眼科受训人员提供了可获取的参考图像资源。然而,这一工具在这方面的准确性和质量尚不清楚。我们旨在评估选定视网膜病变 GIS 图像的准确性和质量。方法 我们对美国眼科学会住院医师系列教材中 15 种常见和 15 种罕见视网膜疾病的 GIS 进行了横断面研究。在咨询玻璃体视网膜外科医生后,对总共 300 张可评估的图像结果进行了评估,以确定图像的准确性和图像来源的可靠性。结果 共审查了 377 幅图像,其中 77 幅在最终分析前被排除。共有 288 张(96%)搜索结果准确描述了所搜索的视网膜疾病,而 12 张(4%)诊断有误。来自患者教育网站的常见视网膜疾病图片多于罕见疾病图片(P P = 0.01)。结论 GIS 搜索结果在眼科教育方面具有一定的准确性。尽管获取多模态视网膜成像示例既方便又快捷,但由于准确性有限、缺乏足够的支持信息以及源网站侧重于患者教育,该工具可能最适合作为住院医师学习的补充资源。
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引用次数: 0
Optimal scheduling of regional integrated energy system considering multiple uncertainties 考虑多不确定性的区域综合能源系统最优调度
Pub Date : 2023-04-01 DOI: 10.1051/E3SCONF/202125602027
H. Xiao, Feiyu Long, Linjun Zeng, Wenqin Zhao, J. Wang, Yihang Li
Integrated energy system (IES) is an effective way to realize the efficient utilization of energy. Under the deregulated electricity market, IES operator gains profits by providing customers with energy service, including electricity, heat or cooling energy. With the deepening of market reform, higher penetration rate of renewable energy, economic risks embed in the IES. Based on this, an optimal scheduling model of regional IES considering uncertainties is proposed, aiming at maximizing the profits. Scenario analysis method has been adopted to model the uncertainties: Markov-Chain-Monte-Carlo (MCMC) sampling method, which has a better performance in fitting the probability distribution, is utilized to generate scenarios; K-means clustering method is applied to narrow down the sampling sets. By replacing the parameters in the deterministic model with the sampling sets, a series of optimal results can be achieved. The case study shows that the cooling storage tank can improve the economic benefits about 4.97% by converting electricity to cooling energy at lower price period and releasing energy at peak hours. Besides, through the proposed optimization model, operators can have a straight understanding of the venture brought by the uncertainties and a more reliable scheduling result is formed for reference.
综合能源系统是实现能源高效利用的有效途径。在解除管制的电力市场下,IES运营商通过向客户提供包括电力、热能或冷能在内的能源服务来获得利润。随着市场改革的深入,可再生能源的渗透率越来越高,经济风险嵌入IES。在此基础上,提出了一个考虑不确定性的区域IES最优调度模型,旨在实现利润最大化。采用情景分析方法对不确定性进行建模:采用马尔可夫链蒙特卡罗(MCMC)采样方法生成情景,该方法在拟合概率分布方面具有较好的性能;采用K-means聚类方法对样本集进行了缩小。通过用采样集替换确定性模型中的参数,可以获得一系列优化结果。案例研究表明,该储冷罐在较低的电价周期内将电力转化为冷却能源,并在高峰时段释放能源,可提高经济效益约4.97%。此外,通过所提出的优化模型,运营商可以直接了解不确定性带来的风险,并形成更可靠的调度结果供参考。
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引用次数: 10
Environmental Aspects of Sustainable Regional Development 可持续区域发展的环境因素
Pub Date : 2023-02-28 DOI: 10.1051/e3sconf/202337103074
E. Karanina, K. Kartavykh
The aim of the present research is to educe the environmental aspects of sustainable development of the regional areas. At present the ecological factors determine largely the opportunities for the economic strength of the regional systems. The article presents the index calculation of the environmental sustainability of the regional system using the example of the Kirov Region. As a result of the research, it was defined that the development of the ecological situation in the region is inclined to be sustainable, and at the same time it is uptrending. The main factors that hamper the improvement in the development of the environmental sustainability of the regional system were educed, some solutions of the problems were offered.
本研究的目的是探讨区域可持续发展的环境因素。目前,生态因素在很大程度上决定了区域系统经济实力的机会。本文以基洛夫地区为例,提出了区域系统环境可持续性指标的计算方法。研究结果表明,该区域生态状况的发展既具有可持续发展的趋势,又具有上升趋势。分析了影响区域系统环境可持续性发展的主要因素,并提出了解决问题的对策。
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引用次数: 0
Community based Asian agrifuture: how it can be achieved 以社区为基础的亚洲农业未来:如何实现
Pub Date : 2023-02-28 DOI: 10.1051/e3sconf/202018701003
N. Ito
Asia is one of the most productive agricultural regions in the world, however the quality control of agricultural food products should be severely and strictly managed from the view point of food security and safety due to the increase of food feeding demand to cover the drastic and rapidly increase of world human population in recent years. In this paper the current status of Asian agriculture is overviewed first, then the Asian agrifuture is discussed and proposed from the community based viewpoint how it should / can be promoted and achieved.
亚洲是世界上最具生产力的农业地区之一,但由于近年来世界人口的急剧增长,粮食喂养需求的增加,从粮食安全的角度来看,应严格管理农产品的质量控制。本文首先概述了亚洲农业的现状,然后从基于社区的角度讨论了亚洲农业的未来,并提出了如何促进和实现亚洲农业的未来。
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引用次数: 0
Virtual Art Exhibition to Encourage Traditional Culture Knowledge for Generation-Z 虚拟艺术展览鼓励z世代了解传统文化
Pub Date : 2023-01-01 DOI: 10.1051/e3sconf/202338804009
A. Kurniawan
Indonesia as a country that has a lot of traditional cultures, requires attention especially among generation-Z to maintain its sustainability. In many cases, various Indonesian cultures are often claimed by other countries as part of their culture, sometimes for the political purposes, economic, or even industrial motives. Thus, it is important to introduce and strengthen the traditional cultures knowledge, especially to generation-Z as the nation's successors. This study was conducted by creating a virtual gallery exhibition as a manifestation of new media forms that can adapt to the trends from generation-Z. The virtual gallery contains traditional attractions, culinary, dance, tourism, music, folklores, and ethnic houses. Some contents in this virtual gallery applies augmented reality technology with image tracking based. This research used mix method with qualitative and quantitative approach to explore the generation-Z expression. Results, virtual gallery gives an effective penetration to increase the traditional culture knowledge among generation- Z.
印度尼西亚作为一个拥有许多传统文化的国家,需要特别关注z世代,以保持其可持续性。在许多情况下,不同的印尼文化经常被其他国家声称为他们文化的一部分,有时是出于政治目的,经济,甚至是工业动机。因此,介绍和加强传统文化知识是很重要的,尤其是对z世代作为国家的继承者。本研究通过创建一个虚拟画廊展览,作为适应z世代趋势的新媒体形式的表现。虚拟画廊包含传统景点、烹饪、舞蹈、旅游、音乐、民间传说和民族房屋。该虚拟图库中的部分内容采用了基于图像跟踪的增强现实技术。本研究采用定性与定量相结合的混合方法对z代表达进行了研究。结果:虚拟画廊对增加Z世代的传统文化知识提供了有效的渗透。
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引用次数: 0
Digital Learning Experience among Newbie Entrepreneurs 新企业家的数字化学习经验
Pub Date : 2023-01-01 DOI: 10.1051/e3sconf/202338804037
M. Herlina, Banu Rinaldi, A. Rahmasari
Entrepreneurship is essential to Indonesia's economic development. It is evidenced by 99.9 percent of all Indonesian firms are micro, small, and medium-sized enterprises (MSMEs). Young generations play an essential part in entrepreneurial ventures since they are more likely to start a new business than older generations. Moreover, Gen Y and Gen Z are more adept with digital learning behaviors. This study adds significantly to the existing entrepreneurial literature by examining social media learning on knowledge-based activities. The Rasch model was used in this study. It evaluated social media as a digital platform where newbie entrepreneurs can use resources and capabilities through knowledge-based activities to develop digital learning among them. The study's outcomes demonstrate a significant difference in exploitative behaviors between gen Y and gen Z. On the contrary, there are no significant differences in both generations' explorative and knowledge-sharing behaviors. It means they have the same level of explorative and knowledge-sharing behaviors.
企业家精神对印尼经济发展至关重要。99.9%的印尼企业是微型、小型和中型企业(MSMEs),这证明了这一点。年轻一代在创业中起着至关重要的作用,因为他们比老一辈更有可能创办新企业。此外,Y世代和Z世代更擅长数字化学习行为。本研究通过考察社交媒体学习对知识型活动的影响,对现有创业文献有了重大补充。本研究采用Rasch模型。它将社交媒体评价为一个数字平台,新手企业家可以通过以知识为基础的活动利用资源和能力,在他们之间发展数字学习。研究结果表明,Y世代和z世代在剥削行为上存在显著差异,相反,两代人在探索和知识共享行为上没有显著差异。这意味着他们具有相同水平的探索和知识共享行为。
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引用次数: 0
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