Emerging Infectious Diseases最新文献

Human granulocytic anaplasmosis is a tickborne infection characterized by fever, thrombocytopenia, leukopenia, transaminitis, or a combination of those. Treatment must be prompt and appropriately targeted to prevent clinical decompensation. We discuss an unusual cluster of 16 probable cases in Ontario, Canada, during June–August 2021.

We identified hepatitis E virus (HEV) 3ra, a potentially zoonotic subtype, in rabbits in Ukraine, which highlights their potential role as reservoirs. Screening of rabbit fecal samples identified HEV-3ra. Public health services in this country should improve HEV surveillance and expand HEV sampling.

The 2058T macrolide resistance–associated mutation in 23S rRNA has emerged in Mycoplasma genitalium in France. Using mgpB typing, we documented the spread of a macrolide- and moxifloxacin-resistant ST159 clone, harboring the A2058T and ParC Ser83Ile mutations. In France, that clone is likely circulating among men who have sex with men.

Serum samples from wild mammals inhabiting Alaska, USA, showed that 4 species, including Ursus arctos bears and Vulpes vulpes foxes, were exposed to influenza A(H5N1) viruses. Results indicated some mammals in Alaska survived H5N1 virus infection. Surveillance efforts may be improved by incorporating information on susceptibility and detectable immune responses among wild mammals.

We report Sindbis virus circulation in the Netherlands based on serologic evidence found in 12 wild birds and 3 horses (2021–2022). Tested mosquitoes were molecularly negative, and humans were serologically negative. Veterinarians and health practitioners in the Netherlands should be aware of the importance of surveillance for Sindbis virus.

Prion diseases, including chronic wasting disease (CWD), are caused by prions, which are misfolded aggregates of normal cellular prion protein. Prions possess many characteristics that distinguish them from conventional pathogens, in particular, an extraordinary recalcitrance to inactivation and a propensity to avidly bind to surfaces. In middle to late stages of CWD, prions begin accumulating in cervid muscle tissues. Those features collectively create scenarios in which occupational hazards arise for workers processing venison and pose risks to consumers through direct prion exposure through ingestion and cross-contamination of food products. In this study, we demonstrate that steel and plastic surfaces used in venison processing can be directly contaminated with CWD prions and that cross-contamination of CWD-negative venison can occur from equipment that had previously been used with CWD-positive venison. We also show that several decontaminant solutions (commercial bleach and potassium peroxymonosulfate) are efficacious for prion inactivation on those same surfaces.

Brucella suis infection in the United States is typically from feral swine exposure. We describe a case of B. suis cardiac implantable device infection in a man exposed to meat and blood from feral swine in Florida, USA. The infection was diagnosed using culture, molecular diagnostics, and whole-genome sequencing.

The bacterium Treponema pallidum pertenue causes yaws in humans and nonhuman primates. We describe 33% T. pallidum pertenue seropositivity in 9 species of nonhuman primates in Uganda and Rwanda, seroconversion during a lethal outbreak and a novel bacterial genomic lineage. Yaws may threaten both public health and conservation in the region.

Long-term serologic surveillance of red-legged partridges suggests emergence of Bagaza virus in Portugal in 2021, associated with disease outbreaks in this species. Results also reveal sporadic circulation of Usutu virus and endemic circulation of West Nile virus, highlighting the role of red-legged partridges in the transmission and maintenance cycle and as sentinels of orthoflaviviruses.