Pub Date : 2026-01-01Epub Date: 2025-12-22DOI: 10.1016/j.eimc.2025.503044
Iñaki Comas
{"title":"Increasing clinical and public health role of Mycobacterium tuberculosis genomics","authors":"Iñaki Comas","doi":"10.1016/j.eimc.2025.503044","DOIUrl":"10.1016/j.eimc.2025.503044","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503044"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-23DOI: 10.1016/j.eimc.2025.503049
Verónica Andrade-Amaráz, José Pedro Elizalde-Díaz
Introduction
Dengue virus infection remains a major public health challenge in tropical regions, with heterogeneous progression to severe disease.
Methods
We conducted a prospective longitudinal study of 362 laboratory-confirmed dengue patients, stratified by sex and the presence of warning signs. Serial hematological, hepatic and renal markers were collected over 96 h (at 24 h, 48 h, 72 h, and 96 h after symptom onset) to analyze their dynamic evolution.
Results
Patients with warning signs persisting beyond 48 h exhibited progressive hematological and hepatic deterioration, unlike those without warning signs. This was characterized by progressively declining platelet and neutrophil counts, elevated hematocrit, and rising AST/ALT levels. These worsening trends were more pronounced in women, who also showed a higher prevalence of warning signs (32% vs 25% in men).
Conclusion
The persistence of warning signs beyond 48 h represents a clinically relevant threshold for hematological and hepatic deterioration, supporting the need for protocolized monitoring – including serial platelet counts, hematocrit, and liver enzymes – during this critical window to enable early intervention in high-risk patients.
{"title":"Dengue warning signs persisting post-48 h demand monitoring to avert severe complications","authors":"Verónica Andrade-Amaráz, José Pedro Elizalde-Díaz","doi":"10.1016/j.eimc.2025.503049","DOIUrl":"10.1016/j.eimc.2025.503049","url":null,"abstract":"<div><h3>Introduction</h3><div>Dengue virus infection remains a major public health challenge in tropical regions, with heterogeneous progression to severe disease.</div></div><div><h3>Methods</h3><div>We conducted a prospective longitudinal study of 362 laboratory-confirmed dengue patients, stratified by sex and the presence of warning signs. Serial hematological, hepatic and renal markers were collected over 96<!--> <!-->h (at 24<!--> <!-->h, 48<!--> <!-->h, 72<!--> <!-->h, and 96<!--> <!-->h after symptom onset) to analyze their dynamic evolution.</div></div><div><h3>Results</h3><div>Patients with warning signs persisting beyond 48<!--> <!-->h exhibited progressive hematological and hepatic deterioration, unlike those without warning signs. This was characterized by progressively declining platelet and neutrophil counts, elevated hematocrit, and rising AST/ALT levels. These worsening trends were more pronounced in women, who also showed a higher prevalence of warning signs (32% vs 25% in men).</div></div><div><h3>Conclusion</h3><div>The persistence of warning signs beyond 48<!--> <!-->h represents a clinically relevant threshold for hematological and hepatic deterioration, supporting the need for protocolized monitoring – including serial platelet counts, hematocrit, and liver enzymes – during this critical window to enable early intervention in high-risk patients.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503049"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-23DOI: 10.1016/j.eimc.2025.503051
María Asunción Pérez-Jacoiste Asín , Andrea Navarro Flores , Anatolio Alonso Crespo , Ana Pérez-Ayala , Irene Losada Galván , Begoña de Dios , Pilar Hernández-Jiménez , Manuel Gil-Mosquera , Francisco Jiménez-Morillas , Carlos Lumbreras , Manuel Lizasoain , Juan María Herrero-Martínez
Introduction
The number of cases of malaria is increasing in Spain due to tourism and migration. Unfamiliarity with this disease may lead doctors to misrecognize its severity and over-/under-treat it. We aimed to analyse the adequacy of treatment according to malaria severity.
Methods
Single-centre retrospective study at “Hospital 12 de Octubre” (Madrid). We identified all patients over 16-years-old with symptomatic malaria from January 2015 to December 2023. The severity of malaria was defined according to WHO criteria. Parenteral artesunate was the treatment of choice for severe malaria. Oral artemisinin combination or atovaquone/proguanil were used for non-severe malaria.
Results
We identified 64 patients (median age 39,5 years (IQR 32,25-47), 75% Visiting Friends and Relatives. Malaria was severe in 15 patients (23.4%). Antimalarial treatment was adequate to severity in 46 patients (71.8%). Three cases classified as severe malaria received oral treatment while 15 cases apparently non-severe received parenteral artesunate. Those who received oral treatment for severe malaria had been misclassified (mild epistaxis, chronic renal insufficiency, and 3.5% parasitaemia in an immigrant). Among those treated parenterally for non-severe malaria, four had oral intolerance and in the remaining eleven, there was an overuse of artesunate. The main reason for artesunate overuse was the presence of thrombocytopenia (median platelet-count: 33,000/mm3, IQR: 28,000-51,000/mm3).
Conclusions
Antimalarial treatments were mostly adequate, especially in severe cases. The most common reason for artesunate overuse was the presence of thrombocytopenia, which is not included in the WHO criteria for severe malaria.
{"title":"Adecuación del tratamiento de la malaria de acuerdo con los criterios de gravedad definidos por la Organización Mundial de la Salud en un país no endémico","authors":"María Asunción Pérez-Jacoiste Asín , Andrea Navarro Flores , Anatolio Alonso Crespo , Ana Pérez-Ayala , Irene Losada Galván , Begoña de Dios , Pilar Hernández-Jiménez , Manuel Gil-Mosquera , Francisco Jiménez-Morillas , Carlos Lumbreras , Manuel Lizasoain , Juan María Herrero-Martínez","doi":"10.1016/j.eimc.2025.503051","DOIUrl":"10.1016/j.eimc.2025.503051","url":null,"abstract":"<div><h3>Introduction</h3><div>The number of cases of malaria is increasing in Spain due to tourism and migration. Unfamiliarity with this disease may lead doctors to misrecognize its severity and over-/under-treat it. We aimed to analyse the adequacy of treatment according to malaria severity.</div></div><div><h3>Methods</h3><div>Single-centre retrospective study at “Hospital 12 de Octubre” (Madrid). We identified all patients over 16-years-old with symptomatic malaria from January 2015 to December 2023. The severity of malaria was defined according to WHO criteria. Parenteral artesunate was the treatment of choice for severe malaria. Oral artemisinin combination or atovaquone/proguanil were used for non-severe malaria.</div></div><div><h3>Results</h3><div>We identified 64 patients (median age 39,5 years (IQR 32,25-47), 75% <em>Visiting Friends and Relatives</em>. Malaria was severe in 15 patients (23.4%). Antimalarial treatment was adequate to severity in 46 patients (71.8%). Three cases classified as severe malaria received oral treatment while 15 cases apparently non-severe received parenteral artesunate. Those who received oral treatment for severe malaria had been misclassified (mild epistaxis, chronic renal insufficiency, and 3.5% parasitaemia in an immigrant). Among those treated parenterally for non-severe malaria, four had oral intolerance and in the remaining eleven, there was an overuse of artesunate. The main reason for artesunate overuse was the presence of thrombocytopenia (median platelet-count: 33,000/mm3, IQR: 28,000-51,000/mm3).</div></div><div><h3>Conclusions</h3><div>Antimalarial treatments were mostly adequate, especially in severe cases. The most common reason for artesunate overuse was the presence of thrombocytopenia, which is not included in the WHO criteria for severe malaria.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503051"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-21DOI: 10.1016/j.eimc.2025.503046
José Miguel Gómez Verdú , Sergio Alemán Belando
{"title":"Reply to “Factors associated with glucocorticoid dosing in treating patients with noncritical COVID-19 pneumonia: Insights from an artificial intelligence-based CT imaging analysis”","authors":"José Miguel Gómez Verdú , Sergio Alemán Belando","doi":"10.1016/j.eimc.2025.503046","DOIUrl":"10.1016/j.eimc.2025.503046","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503046"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-21DOI: 10.1016/j.eimc.2025.503034
Javier García-Abellán, Mar Masiá, Félix Gutiérrez
{"title":"Absceso hepático amebiano tras las inundaciones ocasionadas por la DANA de octubre de 2024 en Valencia, España: un caso centinela de riesgo parasitario emergente en entornos no endémicos","authors":"Javier García-Abellán, Mar Masiá, Félix Gutiérrez","doi":"10.1016/j.eimc.2025.503034","DOIUrl":"10.1016/j.eimc.2025.503034","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503034"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-22DOI: 10.1016/j.eimc.2025.503057
Lucía Cayuela , Clara Peiró Villalba , Beatriz Valle Borrego , Aurelio Cayuela
Introduction
This study aimed to describe national and regional trends in infective endocarditis (IE) mortality in Spain.
Methods
This ecological study analyzed IE mortality trends in Spain from 1999 to 2023 using data from the Spanish National Institute of Statistics. Age-standardized mortality rates (ASMRs) were calculated using direct standardization to the 2013 European Standard Population. Joinpoint regression analysis identified significant shifts in trend trajectories, calculating Annual Percentage Change (APC) and Average Annual Percent Change (AAPC). Regional disparities were assessed using Standardized Mortality Ratios (SMRs) for 2023.
Results
Between 1999 and 2023, 29,766 IE deaths occurred in Spain; 58.0% were women, and 89.0% were aged ≥65 years. Men's ASMR increased from 2.46 to 2.95 per 100,000 (AAPC: +1.2%), showing significant rise from 1999 to 2010 (APC: +2.1%) followed by stabilization. Conversely, women's ASMR declined from 2.60 to 2.00 per 100,000 (AAPC: −0.5%), with initial increase (1999–2017, APC: +0.9%) followed by marked decline (2017–2023, APC: −4.9%).
Regional variations were notable. Among men, Galicia (AAPC: +3.7%) and Asturias (+3.4%) showed steepest increases, while Castile and León declined (−3.0%). In 2023, Navarre (SMR: 2.01) and Galicia (SMR: 1.93) had nearly double national IE mortality risk. For women, Galicia had most pronounced increase (AAPC: 4.1%), while significant declines occurred in Castile and León (AAPC: −4.1%). In 2023, Navarre (SMR: 2.46) and Galicia (SMR: 2.00) exhibited significantly elevated mortality.
Conclusions
IE mortality in Spain exhibits complex sex-specific trends and persistent regional disparities, underscoring the need for targeted, equitable public health interventions.
{"title":"Regional and sex differences in infective endocarditis mortality in Spain","authors":"Lucía Cayuela , Clara Peiró Villalba , Beatriz Valle Borrego , Aurelio Cayuela","doi":"10.1016/j.eimc.2025.503057","DOIUrl":"10.1016/j.eimc.2025.503057","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to describe national and regional trends in infective endocarditis (IE) mortality in Spain.</div></div><div><h3>Methods</h3><div>This ecological study analyzed IE mortality trends in Spain from 1999 to 2023 using data from the Spanish National Institute of Statistics. Age-standardized mortality rates (ASMRs) were calculated using direct standardization to the 2013 European Standard Population. Joinpoint regression analysis identified significant shifts in trend trajectories, calculating Annual Percentage Change (APC) and Average Annual Percent Change (AAPC). Regional disparities were assessed using Standardized Mortality Ratios (SMRs) for 2023.</div></div><div><h3>Results</h3><div>Between 1999 and 2023, 29,766 IE deaths occurred in Spain; 58.0% were women, and 89.0% were aged ≥65 years. Men's ASMR increased from 2.46 to 2.95 per 100,000 (AAPC: +1.2%), showing significant rise from 1999 to 2010 (APC: +2.1%) followed by stabilization. Conversely, women's ASMR declined from 2.60 to 2.00 per 100,000 (AAPC: −0.5%), with initial increase (1999–2017, APC: +0.9%) followed by marked decline (2017–2023, APC: −4.9%).</div><div>Regional variations were notable. Among men, Galicia (AAPC: +3.7%) and Asturias (+3.4%) showed steepest increases, while Castile and León declined (−3.0%). In 2023, Navarre (SMR: 2.01) and Galicia (SMR: 1.93) had nearly double national IE mortality risk. For women, Galicia had most pronounced increase (AAPC: 4.1%), while significant declines occurred in Castile and León (AAPC: −4.1%). In 2023, Navarre (SMR: 2.46) and Galicia (SMR: 2.00) exhibited significantly elevated mortality.</div></div><div><h3>Conclusions</h3><div>IE mortality in Spain exhibits complex sex-specific trends and persistent regional disparities, underscoring the need for targeted, equitable public health interventions.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503057"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-26DOI: 10.1016/j.eimc.2025.503032
Valeria Ferrando-Mérida , Marina Machado , Carmen Cuenca , Rubén Alonso , Patricia Muñoz , Emilio Bouza
Introduction
Persistent Staphylococcus aureus bacteremia (SAB) is associated with high mortality and requires prompt identification and control of the infectious source. Prostatic abscesses, though rare, are an underrecognized cause of persistent SAB, especially in patients with urinary symptoms and comorbidities.
Methods
We present two cases of persistent methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia in which no initial focus was identified despite extensive evaluation. Further investigation led to the diagnosis of prostatic abscesses as the underlying source.
Results
Both patients underwent transurethral drainage of the abscesses in combination with prolonged antibiotic therapy. This combined approach resulted in resolution of the bacteremia and favorable clinical outcomes.
Conclusions
Prostatic abscesses should be considered in the differential diagnosis of persistent SAB, particularly in patients with suggestive urinary symptoms or risk factors. Timely recognition and appropriate source control through surgical drainage and antibiotics are essential for achieving clinical cure.
{"title":"Prostatic abscesses as a cause of persistent Staphylococcus aureus bacteremia","authors":"Valeria Ferrando-Mérida , Marina Machado , Carmen Cuenca , Rubén Alonso , Patricia Muñoz , Emilio Bouza","doi":"10.1016/j.eimc.2025.503032","DOIUrl":"10.1016/j.eimc.2025.503032","url":null,"abstract":"<div><h3>Introduction</h3><div>Persistent <em>Staphylococcus aureus</em> bacteremia (SAB) is associated with high mortality and requires prompt identification and control of the infectious source. Prostatic abscesses, though rare, are an underrecognized cause of persistent SAB, especially in patients with urinary symptoms and comorbidities.</div></div><div><h3>Methods</h3><div>We present two cases of persistent methicillin-susceptible <em>Staphylococcus aureus</em> (MSSA) bacteremia in which no initial focus was identified despite extensive evaluation. Further investigation led to the diagnosis of prostatic abscesses as the underlying source.</div></div><div><h3>Results</h3><div>Both patients underwent transurethral drainage of the abscesses in combination with prolonged antibiotic therapy. This combined approach resulted in resolution of the bacteremia and favorable clinical outcomes.</div></div><div><h3>Conclusions</h3><div>Prostatic abscesses should be considered in the differential diagnosis of persistent SAB, particularly in patients with suggestive urinary symptoms or risk factors. Timely recognition and appropriate source control through surgical drainage and antibiotics are essential for achieving clinical cure.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503032"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-20DOI: 10.1016/j.eimc.2025.503027
Mario Fernández-Ruiz , Rafael San-Juan , María Milagro Montero , José Ramón Paño-Pardo , Jordi Carratalà , Jesús Fortún , Miguel Salavert , Julián Torre-Cisneros , José María Aguado , en representación de los miembros del Grupo OPENIN («Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones»)
Due to its high incidence, urinary tract infection (UTI) is a common cause of health resources utilization and antibiotic prescription in both outpatient and inpatient settings. The OPENIN («Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones») Group is composed of Infectious Diseases specialists and Microbiologists and aims at generating recommendations that can contribute to improve the approach to processes with high impact on the health system based on a review of the best available evidence. The second Group meeting (held in October 2024) sought to answer the following questions: Can we optimize the syndromic and microbiological diagnosis of UTI? Is it possible to improve antibiotic treatment practices? And finally, are the different interventions (non-pharmacological measures, antibiotic prophylaxis, bacterial vaccines or probiotics, among others) effective in reducing the risk of recurrences? The present review summarizes the literature scrutinized for that meeting and offers a series of expert recommendations.
尿路感染（UTI）由于其高发病率，是门诊和住院卫生资源利用和抗生素处方的常见原因。OPENIN（«Optimización de procesos clínicos para el diagnóstico y tratamiento de infeciones»）小组由传染病专家和微生物学家组成，旨在根据对现有最佳证据的审查，提出有助于改进对卫生系统有重大影响的过程的方法的建议。第二次小组会议（于2024年10月举行）旨在回答以下问题：我们能否优化尿路感染的综合征和微生物诊断？是否有可能改进抗生素治疗方法？最后，不同的干预措施（非药物措施、抗生素预防、细菌疫苗或益生菌等）是否能有效降低复发风险？本评论总结了为该会议审查的文献，并提出了一系列专家建议。
{"title":"¿Cómo podemos optimizar el abordaje diagnóstico y terapéutico de la infección de tracto urinario? Una opinión de expertos","authors":"Mario Fernández-Ruiz , Rafael San-Juan , María Milagro Montero , José Ramón Paño-Pardo , Jordi Carratalà , Jesús Fortún , Miguel Salavert , Julián Torre-Cisneros , José María Aguado , en representación de los miembros del Grupo OPENIN («Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones»)","doi":"10.1016/j.eimc.2025.503027","DOIUrl":"10.1016/j.eimc.2025.503027","url":null,"abstract":"<div><div>Due to its high incidence, urinary tract infection (UTI) is a common cause of health resources utilization and antibiotic prescription in both outpatient and inpatient settings. The OPENIN («Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones») Group is composed of Infectious Diseases specialists and Microbiologists and aims at generating recommendations that can contribute to improve the approach to processes with high impact on the health system based on a review of the best available evidence. The second Group meeting (held in October 2024) sought to answer the following questions: Can we optimize the syndromic and microbiological diagnosis of UTI? Is it possible to improve antibiotic treatment practices? And finally, are the different interventions (non-pharmacological measures, antibiotic prophylaxis, bacterial vaccines or probiotics, among others) effective in reducing the risk of recurrences? The present review summarizes the literature scrutinized for that meeting and offers a series of expert recommendations.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503027"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-12-22DOI: 10.1016/j.eimc.2025.503043
Carmen Frías Ruiz , Gema García de la Rosa , Noelia Hernando Parreño , Francisco Martínez Bugallo
{"title":"Desenmascarando al patógeno oculto: hemólisis masiva y sepsis fulminante","authors":"Carmen Frías Ruiz , Gema García de la Rosa , Noelia Hernando Parreño , Francisco Martínez Bugallo","doi":"10.1016/j.eimc.2025.503043","DOIUrl":"10.1016/j.eimc.2025.503043","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"44 1","pages":"Article 503043"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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