Pub Date : 2025-11-01DOI: 10.1016/j.eimc.2025.06.006
Hinpetch Daungsupawong , Viroj Wiwanitkit
{"title":"Emergence of Oropouche virus among international travelers: Correspondence","authors":"Hinpetch Daungsupawong , Viroj Wiwanitkit","doi":"10.1016/j.eimc.2025.06.006","DOIUrl":"10.1016/j.eimc.2025.06.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 9","pages":"Page 628"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145425735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.eimc.2025.09.001
Fabrizio Maggi , Daniele Focosi
{"title":"Anelloviruses as a marker of immunosuppression and inflammation in different clinical settings","authors":"Fabrizio Maggi , Daniele Focosi","doi":"10.1016/j.eimc.2025.09.001","DOIUrl":"10.1016/j.eimc.2025.09.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 9","pages":"Pages 552-554"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145425738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.eimc.2025.06.007
Carlos Iniesta , Victoria Hernando , Inma Jarrín , Santiago Pérez de la Cámara , Javier De la Torre-Lima , Vicent Villanueva , Mª Isabel Mayorga , Josefina Belda , Maribel Soteras , Álvaro Torres Lana , Aitziber Echeverria , Olga Monteagudo-Piqueras , Henar Marcos , Wafa Ben Cheikh , Julián-Alexander Portocarrero-Núñez , Débora Álvarez-del Arco , Asunción Diaz , Julia del Amo , SIPrEP
Objectives
Pre-exposure prophylaxis (PrEP) has been available in Spain since November 2019 and implemented nationally in 2021. Monitoring the implementation process is essential to optimize the strategy. This manuscript describes the Spanish PrEP Programme Information System (SIPrEP), its methodology, and characteristics of PrEP users from November 2019 to May 2024.
Methods
Nationwide open cohort that collects data on persons ≥16 years who were prescribed PrEP in Spain. The study included participants with public program PrEP prescriptions since November 1, 2019. The project was piloted and fully implemented in July 2020.
Results
By May 2024, 28,798 people received public program PrEP in Spain, and 4159 users were included in SIPrEP. Most were men (99%, n = 4117), primarily gay, bisexual, and other men who have sex with men (GBMSM) (97%, n = 4005), with a median age of 36 years (IQR: 30–43). Most were born in Spain (74%, n = 3075), and 36% (n = 1503) had university education. Referrals came from STI centers (19%, n = 805) and primary care (20%, n = 820). At entry, 8% (n = 348) had syphilis, 7% chlamydia (n = 270) and 7% (n = 300) had gonococcal infection. Among users, 15% (n = 642) discontinued PrEP, and 34% (n = 216) of them restarted later. There were four HIV seroconversions (incidence 0.12/100 person-years [95% CI: 0.05–0.33]).
Conclusions
SIPrEP provides valuable real-world data for optimizing interventions but requires improved national coverage.
{"title":"SIPrEP: A tool to monitor HIV pre-exposure prophylaxis in Spain","authors":"Carlos Iniesta , Victoria Hernando , Inma Jarrín , Santiago Pérez de la Cámara , Javier De la Torre-Lima , Vicent Villanueva , Mª Isabel Mayorga , Josefina Belda , Maribel Soteras , Álvaro Torres Lana , Aitziber Echeverria , Olga Monteagudo-Piqueras , Henar Marcos , Wafa Ben Cheikh , Julián-Alexander Portocarrero-Núñez , Débora Álvarez-del Arco , Asunción Diaz , Julia del Amo , SIPrEP","doi":"10.1016/j.eimc.2025.06.007","DOIUrl":"10.1016/j.eimc.2025.06.007","url":null,"abstract":"<div><h3>Objectives</h3><div>Pre-exposure prophylaxis (PrEP) has been available in Spain since November 2019 and implemented nationally in 2021. Monitoring the implementation process is essential to optimize the strategy. This manuscript describes the Spanish PrEP Programme Information System (SIPrEP), its methodology, and characteristics of PrEP users from November 2019 to May 2024.</div></div><div><h3>Methods</h3><div>Nationwide open cohort that collects data on persons ≥16 years who were prescribed PrEP in Spain. The study included participants with public program PrEP prescriptions since November 1, 2019. The project was piloted and fully implemented in July 2020.</div></div><div><h3>Results</h3><div>By May 2024, 28,798 people received public program PrEP in Spain, and 4159 users were included in SIPrEP. Most were men (99%, <em>n</em> <!-->=<!--> <!-->4117), primarily gay, bisexual, and other men who have sex with men (GBMSM) (97%, <em>n</em> <!-->=<!--> <!-->4005), with a median age of 36 years (IQR: 30–43). Most were born in Spain (74%, <em>n</em> <!-->=<!--> <!-->3075), and 36% (<em>n</em> <!-->=<!--> <!-->1503) had university education. Referrals came from STI centers (19%, <em>n</em> <!-->=<!--> <!-->805) and primary care (20%, <em>n</em> <!-->=<!--> <!-->820). At entry, 8% (<em>n</em> <!-->=<!--> <!-->348) had syphilis, 7% chlamydia (<em>n</em> <!-->=<!--> <!-->270) and 7% (<em>n</em> <!-->=<!--> <!-->300) had gonococcal infection. Among users, 15% (<em>n</em> <!-->=<!--> <!-->642) discontinued PrEP, and 34% (<em>n</em> <!-->=<!--> <!-->216) of them restarted later. There were four HIV seroconversions (incidence 0.12/100 person-years [95% CI: 0.05–0.33]).</div></div><div><h3>Conclusions</h3><div>SIPrEP provides valuable real-world data for optimizing interventions but requires improved national coverage.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 8","pages":"Pages 515-522"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.eimc.2025.06.015
Daniel N. Marco , Julie Castiaux , Sara Fernández , Eric Mariotte
{"title":"Hairy cell leukemia, Legionella and ibrutinib: Old friends and a new foe","authors":"Daniel N. Marco , Julie Castiaux , Sara Fernández , Eric Mariotte","doi":"10.1016/j.eimc.2025.06.015","DOIUrl":"10.1016/j.eimc.2025.06.015","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 8","pages":"Pages 537-539"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.eimc.2025.04.001
Phillipe Calpe Delgado , Patricia Muñoz , Alberto Pizarro Portillo , Virginia Álvarez Rodríguez , Ángel Iván Díaz Salado , Isabel Arenas Berenguer , Marta Álvarez Alonso , Esther Gargallo García , Fátima Fernández Salgado , Alma Elena Real Martín , Irene Cabrera Rodrigo , Anaura Carrasquel Regalade , María Ángeles Moreno Planelles , Margarita Jurado Otero , Rodrigo Sanz Lorente , Luis Pérez Ordoño , Ana Carrero Fernández , Juan González del Castillo , en representación de la red VIH de Madrid
Introduction
The «Leave your mark» program launched recommendations for HIV screening in emergency departments (ED) when patients presented with certain conditions. It is unknown whether the profile of patients diagnosed in the ED is similar to those reported for general population in epidemiological reports.
Methods
Retrospective study evaluating the characteristics of patients with new HIV diagnosed in 17 ED over a one-year period was developed. Demographic data (sex at birth, age, country of birth), sexual and risk behaviour, diagnosis in ED, number of emergency visits in previous 5 years, time from the ED to the specific HIV consultation, and from ED to start antiretroviral treatment were recorded. Information on the first CD4 and viral load was also collected.
Results
A total of 169 patients were included. There were 122 (72.2%) migrants, 57 (32.5%) heterosexual, and injection drug use was the transmission route in 14 (8.3%) cases. Data reported for the general population were 49.8%, 25.7%, and 1.7%, respectively. Late diagnosis was found in 80 (47.3%) patients (reported figures by the Ministry, 48.7%). Compared to Spanish, migrant were more frequently women (13.1% vs. 6.4%), heterosexual (38.5% vs. 21.3%), and had worse immunological status (median CD4 count of 310 [IQR 132-457] vs. 444 [IQR 215-607]).
Conclusion
ED can play a key role in diagnosing a different patient profile that may not seek care at other healthcare levels.
{"title":"Caracterización de los nuevos diagnósticos de VIH realizados en los servicios de urgencias hospitalarios a partir del programa «Deja tu huella»","authors":"Phillipe Calpe Delgado , Patricia Muñoz , Alberto Pizarro Portillo , Virginia Álvarez Rodríguez , Ángel Iván Díaz Salado , Isabel Arenas Berenguer , Marta Álvarez Alonso , Esther Gargallo García , Fátima Fernández Salgado , Alma Elena Real Martín , Irene Cabrera Rodrigo , Anaura Carrasquel Regalade , María Ángeles Moreno Planelles , Margarita Jurado Otero , Rodrigo Sanz Lorente , Luis Pérez Ordoño , Ana Carrero Fernández , Juan González del Castillo , en representación de la red VIH de Madrid","doi":"10.1016/j.eimc.2025.04.001","DOIUrl":"10.1016/j.eimc.2025.04.001","url":null,"abstract":"<div><h3>Introduction</h3><div>The «Leave your mark» program launched recommendations for HIV screening in emergency departments (ED) when patients presented with certain conditions. It is unknown whether the profile of patients diagnosed in the ED is similar to those reported for general population in epidemiological reports.</div></div><div><h3>Methods</h3><div>Retrospective study evaluating the characteristics of patients with new HIV diagnosed in 17 ED over a one-year period was developed. Demographic data (sex at birth, age, country of birth), sexual and risk behaviour, diagnosis in ED, number of emergency visits in previous 5<!--> <!-->years, time from the ED to the specific HIV consultation, and from ED to start antiretroviral treatment were recorded. Information on the first CD4 and viral load was also collected.</div></div><div><h3>Results</h3><div>A total of 169 patients were included. There were 122 (72.2%) migrants, 57 (32.5%) heterosexual, and injection drug use was the transmission route in 14 (8.3%) cases. Data reported for the general population were 49.8%, 25.7%, and 1.7%, respectively. Late diagnosis was found in 80 (47.3%) patients (reported figures by the Ministry, 48.7%). Compared to Spanish, migrant were more frequently women (13.1% vs. 6.4%), heterosexual (38.5% vs. 21.3%), and had worse immunological status (median CD4 count of 310 [IQR 132-457] vs. 444 [IQR 215-607]).</div></div><div><h3>Conclusion</h3><div>ED can play a key role in diagnosing a different patient profile that may not seek care at other healthcare levels.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 8","pages":"Pages 496-503"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.eimc.2025.01.006
María Ezquerra Marigómez , María José Cárdenas-Isasi , Marta Rosas Cancio-Suárez
{"title":"Relatos de la piel: manifestaciones dermatológicas tras un viaje a Colombia","authors":"María Ezquerra Marigómez , María José Cárdenas-Isasi , Marta Rosas Cancio-Suárez","doi":"10.1016/j.eimc.2025.01.006","DOIUrl":"10.1016/j.eimc.2025.01.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 8","pages":"Pages 529-530"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.eimc.2025.03.004
Manuel Rosa-Fraile , Juan-Ignacio Alós
{"title":"Estreptococo grupo B y antibióticos beta-lactámicos, un nuevo paradigma","authors":"Manuel Rosa-Fraile , Juan-Ignacio Alós","doi":"10.1016/j.eimc.2025.03.004","DOIUrl":"10.1016/j.eimc.2025.03.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 8","pages":"Pages 534-535"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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