Pub Date : 2024-08-01DOI: 10.1016/j.eimc.2024.06.001
Esteban Martinez
{"title":"Vaccination in adults with HIV in Spain: Where are we?","authors":"Esteban Martinez","doi":"10.1016/j.eimc.2024.06.001","DOIUrl":"10.1016/j.eimc.2024.06.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 337-338"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141774391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01DOI: 10.1016/j.eimc.2024.03.009
Javier Velasco Montes , Silvia González Díez , Elena Rivas Cilleros
{"title":"Sobre las limitaciones del diagnóstico de meningitis tuberculosa","authors":"Javier Velasco Montes , Silvia González Díez , Elena Rivas Cilleros","doi":"10.1016/j.eimc.2024.03.009","DOIUrl":"10.1016/j.eimc.2024.03.009","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Page 395"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141774393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2023.11.002
Laura Batista Amaral , Fabianne Carlesse , Luana Rossato
The occurrence of mucormycosis has been observed in individuals with COVID-19. However, there is limited information on the epidemiological factors, presentation, diagnostic certainty, and outcome of this infection in children. PubMed, MEDLINE, Scopus, Embase, Web of Science, LitCovid, and back-references of the identified manuscripts were systematically searched from December 2019 to March 2023. We have identified 14 cases of pediatric mucormycosis in patients with COVID-19. The median age of patients was 10.7 years. Among these cases, 10 were associated with active COVID-19. In 7 cases, the patients had pre-existing diabetes mellitus and concomitant diabetic ketoacidosis. Corticosteroids were administered to treat COVID-19 in 7 of the patients. The most common clinical presentation of the disease was rhino-orbital cerebral mucormycosis. Seven patients died (50%). Given the high mortality rate, clinicians should maintain a high level of clinical suspicion of mucormycosis in pediatric patients with COVID-19.
{"title":"Pediatric mucormycosis associated with COVID-19: A systematic review of clinical cases","authors":"Laura Batista Amaral , Fabianne Carlesse , Luana Rossato","doi":"10.1016/j.eimc.2023.11.002","DOIUrl":"10.1016/j.eimc.2023.11.002","url":null,"abstract":"<div><p>The occurrence of mucormycosis has been observed in individuals with COVID-19. However, there is limited information on the epidemiological factors, presentation, diagnostic certainty, and outcome of this infection in children. PubMed, MEDLINE, Scopus<span>, Embase, Web of Science, LitCovid, and back-references of the identified manuscripts were systematically searched from December 2019 to March 2023. We have identified 14 cases of pediatric mucormycosis in patients with COVID-19. The median age of patients was 10.7 years. Among these cases, 10 were associated with active COVID-19. In 7 cases, the patients had pre-existing diabetes mellitus and concomitant diabetic ketoacidosis. Corticosteroids were administered to treat COVID-19 in 7 of the patients. The most common clinical presentation of the disease was rhino-orbital cerebral mucormycosis. Seven patients died (50%). Given the high mortality rate, clinicians should maintain a high level of clinical suspicion of mucormycosis in pediatric patients with COVID-19.</span></p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 321-326"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139056782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2024.01.009
Paula de la Matta Farrando , Maria Teresa Suay Torres , Anna Sabater Sabaté , Victoria Trenchs Sainz de la Maza , Carles Luaces Cubells , Susanna Hernández Bou
Introduction
Acute respiratory infections (ARI) are a common cause of inappropriate antibiotic prescription (ATB) in pediatrics. FebriDx® is a rapid diagnostic test that differentiates between viral and bacterial infections. The objective is to analyse the impact of FebriDx® on ATB prescription when managing febrile ARI.
Methods
Prospective study carried out in patients aged 1-< 18 years with febrile ARI in the emergency department. FebriDx® was performed and the impact on management was evaluated at follow-up.
Results
A total of 216 patients were included. Clinical assessment and FebriDx® result coincided in 174 (80.5%) cases. A modification of the initial therapeutic plan was made in 22 (52.4%) of the 42 discordant ones (10.2% of the overall patients). In pneumonia the impact was 34.5%; in all cases it involved not prescribing ATB.
Conclusion
FebriDx® could be a useful tool in the management of pediatric patients with febrile ARI to optimize ATB prescription.
{"title":"Evaluación de FebriDx® para el manejo de niños con infección respiratoria aguda febril","authors":"Paula de la Matta Farrando , Maria Teresa Suay Torres , Anna Sabater Sabaté , Victoria Trenchs Sainz de la Maza , Carles Luaces Cubells , Susanna Hernández Bou","doi":"10.1016/j.eimc.2024.01.009","DOIUrl":"10.1016/j.eimc.2024.01.009","url":null,"abstract":"<div><h3>Introduction</h3><p>Acute respiratory infections (ARI) are a common cause of inappropriate antibiotic prescription (ATB) in pediatrics. FebriDx® is a rapid diagnostic test that differentiates between viral and bacterial infections. The objective is to analyse the impact of FebriDx® on ATB prescription when managing febrile ARI.</p></div><div><h3>Methods</h3><p>Prospective study carried out in patients aged 1-<<!--> <!-->18 years with febrile ARI in the emergency department. FebriDx® was performed and the impact on management was evaluated at follow-up.</p></div><div><h3>Results</h3><p>A total of 216 patients were included. Clinical assessment and FebriDx® result coincided in 174 (80.5%) cases. A modification of the initial therapeutic plan was made in 22 (52.4%) of the 42 discordant ones (10.2% of the overall patients). In pneumonia the impact was 34.5%; in all cases it involved not prescribing ATB.</p></div><div><h3>Conclusion</h3><p>FebriDx® could be a useful tool in the management of pediatric patients with febrile ARI to optimize ATB prescription.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 313-316"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140046032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2024.02.004
María Jesús Castaño , María Jesús Alcaraz , Eliseo Albert , David Navarro
{"title":"Pitfalls in the interpretation of results returned by multiplex real-time PCR panels in the diagnosis of non-gonococcal male urethritis: The case of Ureaplasma urealyticum","authors":"María Jesús Castaño , María Jesús Alcaraz , Eliseo Albert , David Navarro","doi":"10.1016/j.eimc.2024.02.004","DOIUrl":"10.1016/j.eimc.2024.02.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 333-334"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140092213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2023.04.004
María Liébana-Rodríguez , Esther Recacha-Villamor , Carmen Díaz-Molina , Patricia Pérez-Palacios , Lina Martín-Hita , Francisca Enríquez-Maroto , José Gutiérrez-Fernández
Objectives
Klebsiella oxytoca can cause nosocomial infections, affecting vulnerable newborns. There are few studies describing nosocomial outbreaks in the neonatal intensive care units (NICU). In this study, a systematic review of the literature was carried out to know the main characteristics of these outbreaks and the evolution of one is described.
Methods
We conducted a systematic review in the Medline database up to July 2022, and present a descriptive study of an outbreak with 21 episodes in the NICU of a tertiary hospital, between September 2021 and January 2022.
Results
Nine articles met the inclusion criteria. The duration of outbreaks was found to be variable, of which 4 (44.4%) lasted for a year or more. Colonization (69%) was more frequent than infections (31%) and the mortality rate was 22.4%. In studies describing sources, the most frequent was the environmental origin (57.1%). In our outbreak there were 15 colonizations and 6 infections. The infections were mild conjunctivitis without sequelae. Molecular typing analysis made it possible to detect 4 different clusters.
Conclusions
There is an important variability in the evolution and results of the published outbreaks, highlighting a greater number of colonized, use of pulsed-field gel electrophoresis (PFGE) techniques for molecular typing and implementation of control measures. Finally, we describe an outbreak in which 21 neonates were affected with mild infections, resolved without sequelae and whose control measures were effective.
{"title":"Brotes por Klebsiella oxytoca en unidades de cuidados intensivos neonatales: análisis de un brote en un hospital de tercer nivel y revisión sistemática","authors":"María Liébana-Rodríguez , Esther Recacha-Villamor , Carmen Díaz-Molina , Patricia Pérez-Palacios , Lina Martín-Hita , Francisca Enríquez-Maroto , José Gutiérrez-Fernández","doi":"10.1016/j.eimc.2023.04.004","DOIUrl":"10.1016/j.eimc.2023.04.004","url":null,"abstract":"<div><h3>Objectives</h3><p><em>Klebsiella oxytoca</em> can cause nosocomial infections, affecting vulnerable newborns. There are few studies describing nosocomial outbreaks in the neonatal intensive care units (NICU). In this study, a systematic review of the literature was carried out to know the main characteristics of these outbreaks and the evolution of one is described.</p></div><div><h3>Methods</h3><p>We conducted a systematic review in the Medline database up to July 2022, and present a descriptive study of an outbreak with 21 episodes in the NICU of a tertiary hospital, between September 2021 and January 2022.</p></div><div><h3>Results</h3><p>Nine articles met the inclusion criteria. The duration of outbreaks was found to be variable, of which 4 (44.4%) lasted for a year or more. Colonization (69%) was more frequent than infections (31%) and the mortality rate was 22.4%. In studies describing sources, the most frequent was the environmental origin (57.1%). In our outbreak there were 15 colonizations and 6 infections. The infections were mild conjunctivitis without sequelae. Molecular typing analysis made it possible to detect 4 different clusters.</p></div><div><h3>Conclusions</h3><p>There is an important variability in the evolution and results of the published outbreaks, highlighting a greater number of colonized, use of pulsed-field gel electrophoresis (PFGE) techniques for molecular typing and implementation of control measures. Finally, we describe an outbreak in which 21 neonates were affected with mild infections, resolved without sequelae and whose control measures were effective.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 294-301"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134518282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2024.01.010
Elisa González de Herrero , Victoriano Moreno , María Luisa Martín-Pena , Enrique Ruiz de Gopegui
{"title":"Una causa inesperada de miopericarditis en un paciente inmunodeprimido","authors":"Elisa González de Herrero , Victoriano Moreno , María Luisa Martín-Pena , Enrique Ruiz de Gopegui","doi":"10.1016/j.eimc.2024.01.010","DOIUrl":"10.1016/j.eimc.2024.01.010","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 331-332"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140126948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2023.11.004
Mar Redero Cascón , Inmaculada Izquierdo , Juan Luis Muñoz Bellido , Moncef Belhassen-Garcia
{"title":"Una interesante pareja de baile en un inmigrante subsahariano","authors":"Mar Redero Cascón , Inmaculada Izquierdo , Juan Luis Muñoz Bellido , Moncef Belhassen-Garcia","doi":"10.1016/j.eimc.2023.11.004","DOIUrl":"10.1016/j.eimc.2023.11.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 327-328"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139410792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2023.04.002
Enrique Contreras-Macías , María de las Aguas Robustillo-Cortés , Ramón Morillo-Verdugo
Objectives
The patient living with HIV (PLWH) profile has changed and with it, the importance of patient-oriented pharmaceutical care (PC) has been highlighted, for which the stratification tool of the Capacity-Motivation-Opportunity (CMO) PC model helps us which adapts to the needs of each patient. To assess the true relevance, our main objective is to evaluate the differences of one-year mortality among PLWH stratified according to this model.
Methods
A single-center observational analytical survival research study including adult PLWH on antiretroviral therapy (ART) from January-2021 to January-2022 treated at hospital pharmacy outpatient service according to CMO pharmaceutical care model.
Results
A total of 428 patients were included, a median age of 51 years (interquartile range 42–57 year). Overall, the number of patients stratified according to the CMO PC model was 86.2% at level 3, 9.8% at level 2, and 4.0% at level 1. Cox proportional hazard model that included the stratification level was associated with a higher mortality, whose level 1 patients had a 99.7% higher mortality (Hazard ratio = 0.0003; 95%CI: 0.001–0.027).
Conclusions
To sum up, mortality of-one year differs when comparing the PC strata of level 1 and non-level 1, although being similar in age and other clinical conditions. This result suggests that the multidimensional stratification tool, included in the CMO PC model, could be used to modulate the patients intensity follow-up and design interventions more tailored to their needs.
目的艾滋病病毒感染者(PLWH)的情况发生了变化,以患者为导向的药物治疗(PC)的重要性也随之凸显,能力-动机-机会(CMO)PC 模型的分层工具可以帮助我们适应每位患者的需求。为了评估其真正的相关性,我们的主要目标是评估根据该模型进行分层的 PLWH 一年死亡率的差异。结果 共纳入 428 名患者,中位年龄为 51 岁(四分位距为 42-57 岁)。总体而言,根据 CMO PC 模型进行分层的患者中,86.2% 的患者处于 3 级,9.8% 的患者处于 2 级,4.0% 的患者处于 1 级。结论综上所述,尽管年龄和其他临床条件相似,但将 PC 分层 1 级和非 PC 分层 1 级的患者进行比较,其一年的死亡率是不同的。这一结果表明,CMO PC 模型中包含的多维分层工具可用于调整患者的随访强度,并设计出更符合患者需求的干预措施。
{"title":"Correlates of one-year mortality among patients living with HIV according to the stratification level of the pharmaceutical care model","authors":"Enrique Contreras-Macías , María de las Aguas Robustillo-Cortés , Ramón Morillo-Verdugo","doi":"10.1016/j.eimc.2023.04.002","DOIUrl":"10.1016/j.eimc.2023.04.002","url":null,"abstract":"<div><h3>Objectives</h3><p>The patient living with HIV (PLWH) profile has changed and with it, the importance of patient-oriented pharmaceutical care (PC) has been highlighted, for which the stratification tool of the Capacity-Motivation-Opportunity (CMO) PC model helps us which adapts to the needs of each patient. To assess the true relevance, our main objective is to evaluate the differences of one-year mortality among PLWH stratified according to this model.</p></div><div><h3>Methods</h3><p>A single-center observational analytical survival research study including adult PLWH on antiretroviral therapy<span> (ART) from January-2021 to January-2022 treated at hospital pharmacy outpatient service according to CMO pharmaceutical care model.</span></p></div><div><h3>Results</h3><p><span>A total of 428 patients were included, a median age of 51 years (interquartile range 42–57 year). Overall, the number of patients stratified according to the CMO PC model was 86.2% at level 3, 9.8% at level 2, and 4.0% at level 1. Cox proportional hazard model that included the stratification level was associated with a higher mortality, whose level 1 patients had a 99.7% higher mortality (Hazard ratio</span> <!-->=<!--> <!-->0.0003; 95%CI: 0.001–0.027).</p></div><div><h3>Conclusions</h3><p>To sum up, mortality of-one year differs when comparing the PC strata of level 1 and non-level 1, although being similar in age and other clinical conditions. This result suggests that the multidimensional stratification tool, included in the CMO PC model, could be used to modulate the patients intensity follow-up and design interventions more tailored to their needs.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 302-307"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41882137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.eimc.2023.04.009
Albert Bernet Sánchez , Alba Bellés Bellés , Mercè García González , Laura Minguell Domingo , Eduard Solé Mir
Introduction
Respiratory syncytial virus (RSV) is the main cause of severe bronchiolitis, especially in infants. The aim of this study is to assess whether codetection of RSV and other respiratory viruses could affect the severity of this infection comparing with unique RSV detection.
Methods
A prospective study from 2016 to 2019 including children under 2 years who were admitted in the Emergency Service of the Hospital Universitari Arnau de Vilanova de Lleida (Spain) was performed. Nasopharyngeal samples from all patients were sent to the laboratory for RSV real-time PCR detection (GeneXpert®). A multiplex PCR that detects other respiratory viruses was done in all RSV-positive samples. Patients’ medical records were checked to collect clinical data (hospital length of stay, BROSJOD score, ICU admission, need for ventilatory support or transfer to a reference hospital). Patients were divided in 2 groups: infants with unique RSV detection and infants with viral codetection. Bivariant analyses were performed to analyze the data obtained.
Results
During the period of study 437 RSV bronchiolitis were diagnosed. In 199 of them (177/437; 45.5%) another respiratory virus was detected concomitantly. Bivariant analyses do not show statistically significant differences between both groups.
Conclusions
Viral codetection in infants with RSV bronchiolitis is frequent. However, it does not seems to affect the severity of this infection.
{"title":"Relevancia clínica de la codetección viral en lactantes con bronquiolitis por virus respiratorio sincitial","authors":"Albert Bernet Sánchez , Alba Bellés Bellés , Mercè García González , Laura Minguell Domingo , Eduard Solé Mir","doi":"10.1016/j.eimc.2023.04.009","DOIUrl":"10.1016/j.eimc.2023.04.009","url":null,"abstract":"<div><h3>Introduction</h3><p>Respiratory syncytial virus (RSV) is the main cause of severe bronchiolitis, especially in infants. The aim of this study is to assess whether codetection of RSV and other respiratory viruses could affect the severity of this infection comparing with unique RSV detection.</p></div><div><h3>Methods</h3><p>A prospective study from 2016 to 2019 including children under 2 years who were admitted in the Emergency Service of the Hospital Universitari Arnau de Vilanova de Lleida (Spain) was performed. Nasopharyngeal samples from all patients were sent to the laboratory for RSV real-time PCR detection (GeneXpert®). A multiplex PCR that detects other respiratory viruses was done in all RSV-positive samples. Patients’ medical records were checked to collect clinical data (hospital length of stay, BROSJOD score, ICU admission, need for ventilatory support or transfer to a reference hospital). Patients were divided in 2 groups: infants with unique RSV detection and infants with viral codetection. Bivariant analyses were performed to analyze the data obtained.</p></div><div><h3>Results</h3><p>During the period of study 437 RSV bronchiolitis were diagnosed. In 199 of them (177/437; 45.5%) another respiratory virus was detected concomitantly. Bivariant analyses do not show statistically significant differences between both groups.</p></div><div><h3>Conclusions</h3><p>Viral codetection in infants with RSV bronchiolitis is frequent. However, it does not seems to affect the severity of this infection.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 308-312"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121298669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}