Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"Inflammation in HIV: A persistent challenge","authors":"Julia Barrado , Vicente Estrada","doi":"10.1016/j.eimc.2024.09.007","DOIUrl":"10.1016/j.eimc.2024.09.007","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Page 467"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respuesta a «Caracterización de las infecciones de herida entre pacientes procedentes de la guerra ruso-ucraniana en un hospital Role 4»","authors":"María del Mar Rodero Roldán , Valentín Yuste Benavente , Ana Isabel López Calleja , Juan Manuel García-Lechuz","doi":"10.1016/j.eimc.2024.06.014","DOIUrl":"10.1016/j.eimc.2024.06.014","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Page 542"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent invasive pneumococcal disease (RIPD) in an immunocompromised patient","authors":"Ivonne Andrea Torres Jiménez , Sara de Miguel García , Julio Sempere García , Juan Carlos Sanz Moreno","doi":"10.1016/j.eimc.2024.06.004","DOIUrl":"10.1016/j.eimc.2024.06.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 533-535"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meningitis tuberculosa por Mycobacterium africanum en España, a propósito de un caso","authors":"Nuria Torrellas Bertran , Gemma Garcia Continente , Oscar Villarreal","doi":"10.1016/j.eimc.2024.06.007","DOIUrl":"10.1016/j.eimc.2024.06.007","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 536-538"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad predictiva de mortalidad de las escalas qSOFA, NEWS y GYM en el paciente anciano con infección en urgencias: estudio EDEN-5","authors":"","doi":"10.1016/j.eimc.2023.07.004","DOIUrl":"10.1016/j.eimc.2023.07.004","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the prognostic accuracy of the scores NEWS, qSOFA, GYM used in hospital emergency department (ED) in the assessment of elderly patients who consult for an infectious disease.</div></div><div><h3>Methods</h3><div>Data from the EDEN (Emergency Department and Elderly Needs) cohort were used. This retrospective cohort included all patients aged ≥<!--> <!-->65<!--> <!-->years seen in 52 Spanish EDs during two weeks (from 1/4/2019 to 7/4/2019 and 30/3/2020 to 5/4/2020) with an infectious disease diagnosis in the emergency department. Demographic variables, comorbidities, Charlson and Barthel index and needed scores parameters were recorded. The predictive capacity for 30-day mortality of each scale was estimated by calculating the area under the receiver operating characteristic (ROC) curve, and sensitivity and specificity were calculated for different cut-off points. The primary outcome variable was 30-day mortality.</div></div><div><h3>Results</h3><div>Six thousand fifty-four patients were analyzed. Median age was 80<!--> <!-->years (IQR 73-87) and 45.3% women. Nine hundred and ninety-three (16.4%) patients died. NEWS score had better AUC than qSOFA (0.765; 95%<!--> <!-->CI: 0.725-0.806, vs. 0.700; 95%<!--> <span>C</span>I: 0.653-0.746; <em>P</em> <!-->&lt;<!--> <!-->.001) and GYM (0.716; 95%<!--> <!-->CI: 0.675-0.758; <em>P</em> <!-->=<!--> <!-->.024), and there was no difference between qSOFA and GYM (<em>P</em> <!-->=<!--> <!-->.345). The highest sensitivity scores for 30-day mortality were GYM ≥<!--> <!-->1 point (85.4%) while the qSOFA score ≥<!--> <!-->2 points showed high specificity. In the case of the NEWS scale, the cut-off point ≥<!--> <!-->4 showed high sensitivity, while the cut-off point NEWS ≥<!--> <!-->8 showed high specificity.</div></div><div><h3>Conclusion</h3><div>NEWS score showed the highest predictive capacity for 30-day mortality. GYM score ≥<!--> <!-->1 showed a great sensitivity, while qSOFA ≥<!--> <!-->2 scores provide the highest specificity but lower sensitivity.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 468-477"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135852634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes and practices in HIV-related chronic inflammation and cardiovascular risk in Spain","authors":"","doi":"10.1016/j.eimc.2023.07.005","DOIUrl":"10.1016/j.eimc.2023.07.005","url":null,"abstract":"<div><h3>Background</h3><div>People with HIV (PWH) in suppressive antiretroviral treatment suffer from chronic inflammation-related comorbidities, mainly cardiovascular diseases. However, given the lack of specific evidence about inflammation in PWH, clinical guidelines do not provide recommendations for the management of this issue. To date, physician awareness of inflammation in PWH remains unclear. We analyzed the knowledge, attitudes, and practices (KAP) related to inflammation, particularly in the clinical management of PWH, of infectious disease specialists (IDS)/internists compared to other specialists treating inflammation directly (rheumatologists) or its cardiovascular consequences (cardiologists).</div></div><div><h3>Methods</h3><div>A committee of IDS/internists treating PWH, cardiologists, and rheumatologists designed the KAP questionnaire. The survey was completed by 405 participants (135 physicians per specialty) stratified by Spanish geography, hospital size, and number of PWH under care (IDS/internists only).</div></div><div><h3>Results</h3><div>IDS/internists treating PWH scored higher than cardiologists and rheumatologists on knowledge of inflammation (5.5<!--> <!-->±<!--> <!-->1.4 out of 8 points vs. 5.2<!--> <!-->±<!--> <!-->1.3 and 4.6<!--> <!-->±<!--> <!-->1.4 points, respectively; <em>p</em> <!-->&lt;<!--> <!-->0.05). Nevertheless, rheumatologists showed the most proactive attitude toward inflammation (i.e., biomarkers monitoring, anti-inflammatory drug prescription and cardiologist referral), followed by cardiologists and IDS/internists (13<!--> <!-->±<!--> <!-->3 of a total of 16 points vs. 11<!--> <!-->±<!--> <!-->3 and 10<!--> <!-->±<!--> <!-->3.3 points, respectively; <em>p</em> <!-->&lt;<!--> <!-->0.05), irrespective of hospital size and years of experience. Most IDS/internists (59%) include inflammation in their therapeutic recommendations. However, in IDS/internists treating PWH, we observed a negative correlation between years of experience and concern about the clinical consequences of inflammation.</div></div><div><h3>Conclusion</h3><div>Our findings show that, compared to other specialists, infectious disease specialists/internists have high knowledge about inflammation in HIV infection, but, in the absence of scientific evidence to base their decisions on inflammatory markers, the therapeutic implications are scarce. The results support the need for more evidence on the monitoring and treatment of inflammation in PWH.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 484-491"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and microbiological characteristics of Eggerthella lenta causing bacteremia","authors":"Domingo Fernández Vecilla ,&nbsp;Mikel Joseba Urrutikoetxea Gutiérrez ,&nbsp;Mary Paz Roche Matheus ,&nbsp;Felicitas Elena Calvo Muro ,&nbsp;José Luis Díaz de Tuesta del Arco","doi":"10.1016/j.eimc.2024.05.003","DOIUrl":"10.1016/j.eimc.2024.05.003","url":null,"abstract":"<div><div><span><em>Eggerthella lenta</em></span><span> is an obligate anaerobic, Gram-positive bacilli, belonging to the human microbiota of gastrointestinal and female reproductive tracts, oral cavity and prostate gland. In this article, we aim to describe clinical and microbiological characteristics of seven </span><em>E. lenta</em> strains causing bacteremia. We conducted a descriptive retrospective study including all <em>E. lenta</em> strains causing bacteremia, from February 2019 to August 2023 at the Basurto University Hospital. Seven patients were included in the study with a mean age of 72.7 years. Six patients presented risk factors associated with bacterial infections. All patients were admitted to the hospital because of suspicious of bloodstream infection associated with abdominal symptoms for intravenous antibiotic treatment. Four <em>E. lenta</em> isolates were resistant to penicillin, while all isolates presented high MICs to piperacillin/tazobactam and low MICs to amoxicillin/clavulanic acid. All patients recovered without no complications.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 512-515"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The current status of arboviruses with major epidemiological significance in Europe","authors":"Fernando de la Calle-Prieto ,&nbsp;Marta Arsuaga ,&nbsp;Graciela Rodríguez-Sevilla ,&nbsp;Nancy Sandoval Paiz ,&nbsp;Marta Díaz-Menéndez","doi":"10.1016/j.eimc.2024.09.002","DOIUrl":"10.1016/j.eimc.2024.09.002","url":null,"abstract":"<div><div>Currently, an increasing impact of some arboviruses has been observed in Europe, mainly Dengue (DENV), Chikungunya (CHIKV), Zika (ZIKV), West Nile (WNV), and Crimean-Congo hemorrhagic fever (CCHFV) analyzed through a One Health perspective that considers their expansion across the continent. Arboviruses are primarily transmitted by vectors such as mosquitoes and ticks, with human activities and climate change playing crucial roles in their spread. The review highlights the ecological and epidemiological aspects of arboviruses, emphasizing the roles of diverse hosts and reservoirs, including humans, animals, and vectors, in their life cycles. The influence of climate change on the ecology of the vector, which potentially favors the arbovirus transmission, is also reviewed. Focusing on diagnosis, prevention and in the absence of specific treatments, the importance of understanding vector–host interactions and environmental impacts to develop effective control and prevention strategies is emphasized. Ongoing research on vaccines and therapies is crucial to mitigate the public health impact of these diseases.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 516-526"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caracterización de las infecciones de herida entre pacientes procedentes de la guerra ruso-ucraniana en un hospital Role 4","authors":"Rafael García-Cañas ,&nbsp;Francisco Javier Areta-Jiménez","doi":"10.1016/j.eimc.2024.06.013","DOIUrl":"10.1016/j.eimc.2024.06.013","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 540-542"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¿Fascitis necrosante por una picadura de araña?","authors":"","doi":"10.1016/j.eimc.2024.01.006","DOIUrl":"10.1016/j.eimc.2024.01.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 529-530"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}