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What for developmentalism in psychiatry? 精神病学中的发展主义是什么?
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-05-09 DOI: 10.1007/s00787-024-02453-3
Yann Craus
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引用次数: 0
Expanding the clinical phenotype of SHANK2-related disorders: childhood apraxia of speech in a patient with a novel SHANK2 pathogenic variant. 扩展 SHANK2 相关疾病的临床表型:一名患有新型 SHANK2 致病变异体的儿童语言障碍患者。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-05-03 DOI: 10.1007/s00787-024-02452-4
Elisa Granocchio, Luca Andreoli, Santina Magazù, Daniela Sarti, Emanuela Leonardi, Alessandra Murgia, Claudia Ciaccio
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引用次数: 0
Optimal exercise intensity for improving executive function in patients with attention deficit hyperactivity disorder: systematic review and network meta-analysis. 改善注意力缺陷多动障碍患者执行功能的最佳运动强度:系统综述和网络荟萃分析。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-06-26 DOI: 10.1007/s00787-024-02507-6
Ji-Wei Chen, Wen-Qian Du, Kun Zhu

This study aimed to compare and rank the effectiveness of optimal exercise intensity in improving executive function in patients with ADHD (Attention deficit hyperactivity disorder, ADHD) through a comprehensive comparison of direct and indirect evidence. A systematic search was performed in five electronic databases to explore the optimal exercise intensity for improving executive function in patients with ADHD by directly and indirectly comparing a variety of exercise intervention intensities. In addition, the isolated effects of exercise on improving executive function in patients with ADHD were explored through classical meta-analysis of paired direct comparisons. Twenty-nine studies were retrieved and included in this study. Classical paired meta-analysis showed that for the patients with ADHD in the age group of 7-17 years, statistical difference was observed for all the parameters of exercise interventions (intensity, frequency, period, and training method), the three dimensions of executive function, the use of medication or not, the high and low quality of the methodological approach. Network meta-analysis showed that high-intensity exercise training was optimal for improving working memory (97.4%) and inhibitory function (85.7%) in patients with ADHD. Meanwhile, moderate-intensity exercise training was optimal for improving cognitive flexibility (77.3%) in patients with ADHD. Moderate to high intensity exercise training shows potential for improving executive function in these patients. Therefore, we recommend applying high-intensity exercise intervention to improve executive function in patients with ADHD to achieve substantial improvement.

本研究旨在通过对直接和间接证据进行综合比较,对最佳运动强度在改善多动症(注意缺陷多动障碍,ADHD)患者执行功能方面的效果进行比较和排序。本研究在五个电子数据库中进行了系统性检索,通过直接和间接比较各种运动干预强度,探索改善多动症患者执行功能的最佳运动强度。此外,还通过配对直接比较的经典荟萃分析,探讨了运动对改善多动症患者执行功能的单独效果。本研究共检索并纳入了 29 项研究。经典配对荟萃分析表明,对于 7-17 岁年龄组的多动症患者,运动干预的所有参数(强度、频率、周期和训练方法)、执行功能的三个维度、是否使用药物、方法质量的高低均存在统计学差异。网络荟萃分析表明,高强度运动训练对改善多动症患者的工作记忆(97.4%)和抑制功能(85.7%)效果最佳。同时,中等强度的运动训练对改善多动症患者的认知灵活性(77.3%)效果最佳。中高强度的运动训练显示出改善这些患者执行功能的潜力。因此,我们建议采用高强度运动干预来改善多动症患者的执行功能,以取得实质性改善。
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引用次数: 0
Paternal intelligence affects school grades in children with and without ADHD - a register-based study. 父亲智力对患有和不患有多动症儿童学习成绩的影响--一项基于登记的研究。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-06-27 DOI: 10.1007/s00787-024-02510-x
Andrea Markkula, Kajsa Igelström, He Zhang, Andrea Johansson Capusan

ADHD profoundly impacts educational attainment, quality of life, and health in young adults. However, certain subgroups of ADHD patients seem to do quite well, potentially due to differences in intelligence and socioeconomic status. Here we used paternal intelligence from the Swedish Defence Conscription and Assessment register, to investigate the role of genetic propensity for intelligence, on school performance in a large cohort of ADHD patients and matched controls. Patients treated for ADHD in Linköping, Sweden between 1995 and 2020 (n = 3262), sex- and age-matched controls (n = 9591) as well as their parents and siblings were identified using regional and national registers. Socioeconomic and demographic data, ADHD diagnosis and treatment and school grades at age 16 for the study population were extracted from Swedish National registers. We explored the associations between paternal intelligence and child school performance using linear mixed models and mediation analyses, taking a wide range of potential covariates into account. Results indicate that paternal intelligence was positively associated with standardized school grades in their offspring (Zadjusted=0.09, 95%CI 0.07, 0.10). This effect was present in both ADHD patients and controls, but ADHD patients had significantly lower standardized grades (Zadjusted=-1.03, 95%CI -1.08, -0.98). Child ADHD did not serve as a mediator for how paternal intelligence affected school grades. Our findings indicate that ADHD prevents children from reaching their academic potential at all levels of paternal intelligence. Increased understanding of the contributions of ADHD, intelligence, and SES to functional outcomes can help clinicians to better personalize interventions to the unique preconditions in each patient.

多动症对青少年的教育程度、生活质量和健康产生了深远的影响。然而,某些亚群的多动症患者似乎表现很好,这可能与智力和社会经济地位的差异有关。在此,我们利用瑞典国防征兵和评估登记册中的父系智力数据,研究了智力遗传倾向对一大批多动症患者和匹配对照组的学习成绩的影响。我们通过地区和国家登记册确定了1995年至2020年间在瑞典林雪平接受治疗的多动症患者(3262人)、性别和年龄匹配的对照组(9591人)及其父母和兄弟姐妹。研究对象的社会经济和人口数据、多动症诊断和治疗以及 16 岁时的在校成绩均来自瑞典国家登记册。我们使用线性混合模型和中介分析探讨了父亲智力与子女学习成绩之间的关系,并考虑了各种潜在的协变量。结果表明,父亲的智力与其后代的标准化学校成绩呈正相关(Zadjusted=0.09,95%CI 0.07,0.10)。这一效应在多动症患者和对照组中都存在,但多动症患者的标准化成绩明显较低(Zadjusted=-1.03,95%CI-1.08,-0.98)。儿童多动症并不是父亲智力影响学习成绩的中介因素。我们的研究结果表明,在父亲智力的各个水平上,多动症都会阻碍儿童发挥其学习潜能。进一步了解多动症、智力和社会经济地位对功能性结果的影响,有助于临床医生更好地针对每个患者的独特先决条件进行个性化干预。
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引用次数: 0
Identifying studies examining the validity of instruments for use as outcome measures in child and adolescent forensic mental health services: a systematic review. 确定用于儿童和青少年法医心理健康服务结果测量工具有效性的研究:系统性综述。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-08-07 DOI: 10.1007/s00787-024-02514-7
Graham Walker, Naomi Wilson, Clare S Allely, Allan Thomson, Helen Smith, Jason Lang

Background: Outcome measurement in child and adolescent forensic mental health services can support service improvement, research, and patient progress evaluation. This systematic review aimed to identify studies which validate structured instruments available for use as outcome measures in the child and adolescent forensic mental health service cohort and assess the quality of these studies.

Methods: A systematic review was conducted following PRISMA guidelines. Studies were identified by searching six online databases in November 2023. The quality and risk of bias of each study meeting inclusion criteria was independently assessed by two authors using the Crowe Critical Appraisal Tool. Results were synthesised narratively.

Results: A total of eight studies were identified which met inclusion criteria. These looked at six instruments which primarily focused on outcome measures in the areas of treatment motivation, level of functioning, psychiatric symptoms, care needs and response to social situations. Papers scored between 17/40 and 30/40 on the Crowe Critical Appraisal Tool. Studies were rated as low (n = 1), moderate (n = 6), high (n = 1) or very high quality (n = 0).

Conclusions: Despite the large number of structured instruments potentially available, evidence for their use as outcome measures in child and adolescent forensic mental health services is limited. Future research should aim to validate current structured instruments for use in the forensic child and adolescent setting, with consideration of whether new instruments should be developed specifically for this group. Such instruments should be developed with both young people as service users and professionals who will be utilising the instrument in mind.

背景:对儿童和青少年法医精神健康服务的结果进行测量,可以为服务改进、研究和患者进展评估提供支持。本系统性综述旨在确定哪些研究验证了可用作儿童和青少年法医精神健康服务结果测量的结构化工具,并评估这些研究的质量:方法:按照 PRISMA 指南进行了系统性综述。2023 年 11 月,通过搜索六个在线数据库确定了相关研究。符合纳入标准的每项研究的质量和偏倚风险均由两位作者使用克罗批判性评估工具进行独立评估。结果以叙述的方式进行综合:共有八项研究符合纳入标准。这些研究考察了六种工具,主要集中在治疗动机、功能水平、精神症状、护理需求和对社会环境的反应等方面的结果测量。论文在克罗批判性评价工具中的得分介于 17/40 和 30/40 之间。研究被评为低质量(n = 1)、中等质量(n = 6)、高质量(n = 1)或极高质量(n = 0):尽管有大量结构化工具可供使用,但将其作为儿童和青少年法医心理健康服务的结果测量工具的证据却很有限。未来的研究应着眼于验证当前结构化工具在儿童和青少年法医环境中的应用,并考虑是否应专门为这一群体开发新的工具。在开发此类工具时,既要考虑到作为服务使用者的青少年,也要考虑到使用工具的专业人员。
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引用次数: 0
Post-traumatic stress disorder in children after discharge from the pediatric intensive care unit: a scoping review. 儿科重症监护室出院后儿童的创伤后应激障碍:范围界定综述。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-06-25 DOI: 10.1007/s00787-024-02505-8
Maoting Tang, Ping Lei Chui, Mei Chan Chong, Xianliang Liu

As the prevalence of post-traumatic stress disorder (PTSD) among children discharged from pediatric intensive care unit (PICU) continues to rise, corresponding research efforts have also increased. This scoping review aimed to review the PTSD prevalence, influencing factors, and tools used for PTSD measurements in children discharged from the PICU. This review employed the five-stage framework proposed by Arksey and O'Malley. The data sources included PubMed, Web of Science, Ovid, ScienceDirect, Springer, Scopus, CNKI, and WANFANG. Studies in English or Chinese published up to September 2023 were eligible for inclusion. The search yielded a total of 3536 results, with 31 articles meeting the inclusion criteria. The included studies reported that the prevalence of PTSD ranged from a minimum of 13% to a maximum of 84.6%. Risk factors for PTSD included medical interventions, child-related factors, and family environment. A total of 17 assessment tools for PTSD in PICU patients were reported. Given the significance of PTSD in this pediatric population, further attention, research, and intervention are warranted to help alleviate the burden of PTSD.

随着创伤后应激障碍(PTSD)在儿科重症监护病房(PICU)出院儿童中的患病率持续上升,相应的研究工作也随之增加。本范围界定综述旨在回顾创伤后应激障碍的患病率、影响因素以及用于测量 PICU 出院儿童创伤后应激障碍的工具。本综述采用了 Arksey 和 O'Malley 提出的五阶段框架。数据来源包括 PubMed、Web of Science、Ovid、ScienceDirect、Springer、Scopus、CNKI 和 WANFANG。截至 2023 年 9 月发表的英文或中文研究均符合纳入条件。搜索结果共计 3536 条,其中 31 篇符合纳入标准。纳入的研究报告显示,创伤后应激障碍的发病率最低为 13%,最高为 84.6%。创伤后应激障碍的风险因素包括医疗干预、儿童相关因素和家庭环境。共有 17 项针对 PICU 患者创伤后应激障碍的评估工具被报道。鉴于创伤后应激障碍在儿科人群中的重要性,我们有必要进一步关注、研究和干预,以帮助减轻创伤后应激障碍的负担。
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引用次数: 0
The associations between interparental conflict and adolescent adjustment: a cross-lagged panel network analysis. 父母间冲突与青少年适应之间的关联:跨滞后面板网络分析。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-07-22 DOI: 10.1007/s00787-024-02525-4
Wenqing Li, Meiru Deng, Pei Wang, Xiaoyu Li, Yingchao Zhang, Yinqiu Zhao, Chi Yang, Jianbing Li

Extensively studied in interparental relationship literature suggests interparental conflict is a risk factor for adolescent adjustment, but the specific, dimension level relationships between interparental conflict and adolescent adjustment remain unclear. This study explored the interactions between the various dimensions of interparental conflict and adolescent adjustment in Chinese adolescents. A total of 1870 Chinese adolescents (42.27% males; Mage = 16.18, SD = 0.43, range = 15-18) completed a survey at two time points spaced three months apart. Data was analyzed using both cross-sectional and longitudinal network analysis. The cross-sectional network analysis found that resolution has the greatest connections with the dimensions of adolescent adjustment, suggesting that adolescents reporting high resolution are more prone to experience concurrent poor adjustment and therefore should be a primary focus of attention. The longitudinal network analysis revealed that, in general, previous hyperactivity-inattention is a significant and strong predictor of future interparental conflict, underscoring a child-driven effect. Meanwhile, prosocial behavior contributes to decreases in both interparental conflict and adjustment problems over time. These findings highlight the importance of addressing hyperactivity-inattention and cultivating prosocial behavior in adolescents as key intervention points-these can help resolve conflicts between parents and reduce adjustment problems for adolescents.

父母间关系的广泛研究表明,父母间冲突是青少年适应的一个危险因素,但父母间冲突与青少年适应之间具体的、维度层面的关系仍不清楚。本研究探讨了中国青少年父母间冲突的各个维度与青少年适应之间的相互作用。共有1870名中国青少年(42.27%为男性;年龄=16.18,标准差=0.43,范围=15-18岁)在两个时间点完成了调查,时间间隔为三个月。我们采用横向和纵向网络分析方法对数据进行了分析。横向网络分析发现,分辨力与青少年适应能力的各个维度有着最大的联系,这表明报告高分辨力的青少年更容易同时出现适应能力差的情况,因此应该成为关注的重点。纵向网络分析显示,一般来说,以前的过度活跃-注意力不集中是未来父母间冲突的一个重要且强有力的预测因素,这突出了儿童驱动效应。同时,随着时间的推移,亲社会行为有助于减少父母间的冲突和适应问题。这些发现凸显了解决青少年过度活跃-注意力不集中问题和培养亲社会行为作为关键干预点的重要性--它们有助于解决父母之间的冲突和减少青少年的适应问题。
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引用次数: 0
Why do young men not seek help for affective mental health issues? A systematic review of perceived barriers and facilitators among adolescent boys and young men. 年轻男性为何不寻求情感心理健康问题的帮助?对青春期男孩和青年男子感知到的障碍和促进因素的系统性研究。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-07-14 DOI: 10.1007/s00787-024-02520-9
Ayesha Sheikh, Chloe Payne-Cook, Stephen Lisk, Ben Carter, June S L Brown

Men are less likely to seek help for their mental health than women, but less is known about the specific patterns of help-seeking in adolescent boys and young men. This is concerning as adolescent boys and young men have high suicide rates but a low take-up of services. It is therefore of particular importance that the access needs of this group are understood. This review sought to identify the barriers and facilitators faced by adolescent boys and young men in help-seeking for affective mental health disorders. A search of the PubMed, APA PsycInfo, and Cochrane databases identified 3961 articles, of which 12 met the inclusion criteria. Six of the studies were qualitative, five were quantitative and one used mixed methods. Two authors independently extracted data and assessed the quality of the articles. Five key themes were identified, including the impact of social norms, with the subthemes of conformity to masculine norms and self-stigma, limited availability of information about mental health, and 'male-friendly' mental health literacy campaigns. Other themes referred to the help-seeking preferences of adolescent boys and young men, in terms of informal or formal and online or offline help-seeking. Some of the factors were well-researched (e.g., conformity to masculine norms as a barrier) whereas other factors (e.g., self-compassion as a facilitator) were less researched. These barriers and facilitators need to be considered in the development of future strategies to improve the help-seeking behaviour of adolescent boys and young men.

与女性相比,男性在心理健康方面寻求帮助的可能性较低,但人们对青春期男孩和青年男性寻求帮助的具体模式却知之甚少。这一点令人担忧,因为青春期男孩和青年男子的自杀率很高,但接受服务的比例却很低。因此,了解这一群体的求助需求尤为重要。本综述旨在确定青春期男孩和青年男子在寻求情感性精神障碍帮助时所面临的障碍和促进因素。通过对 PubMed、APA PsycInfo 和 Cochrane 数据库的检索,我们发现了 3961 篇文章,其中 12 篇符合纳入标准。其中六项研究为定性研究,五项研究为定量研究,一项研究采用了混合方法。两位作者独立提取数据并评估文章质量。研究确定了五个关键主题,包括社会规范的影响,以及符合男性规范和自我污名化、心理健康信息的有限可得性和 "男性友好 "心理健康扫盲运动等副主题。其他主题则涉及少男少女在非正式或正式、在线或离线求助方面的偏好。对其中一些因素进行了深入研究(例如,符合男性规范是一种障碍),而对其他因素(例如,自我同情是一种促进因素)的研究较少。在制定未来战略以改善青春期男孩和青年男子的求助行为时,需要考虑这些障碍和促进因素。
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引用次数: 0
The iceberg model of suicidal ideation and behaviour in Danish adolescents: integration of national registry and self-reported data within a national birth cohort. 丹麦青少年自杀意念和行为的冰山模型:整合全国出生队列中的国家登记数据和自我报告数据。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-06-25 DOI: 10.1007/s00787-024-02503-w
Stine Danielsen, Katrine Strandberg-Larsen, Keith Hawton, Merete Nordentoft, Annette Erlangsen, Trine Madsen

Hospital records are used to identify suicide attempts in many countries but not all individuals present to hospital after a suicide attempt i.e., suggesting a 'hidden number'. Our aim was to present the prevalence of suicide ideation, plans, attempts, and suicides among Danish adolescents, including attempts not resulting in hospital contact. The study population consisted of participants in the Danish National Birth Cohort participating in an 18-year follow-up, with individual-level linkage to national register data. Prevalence was estimated with a variable with mutually exclusive categories ranging from no suicidality to self-reported suicide ideation, -plans, -attempt and hospital-recorded suicide attempt and stratified on sex and parental income. The 'hidden number' was estimated as the ratio between suicide attempts with and without hospital contact. Among 47 858 participants, all aged 18-years, 36% girls and 28% boys reported suicide ideation at least once in their life. In addition, 6% girls and 3% boys had either reported or been recorded with a suicide attempt. For every attempt recorded in the hospital setting, two girls (ratio, 1:2) and six boys (ratio, 1:6) reported having attempted suicide without hospital contact. The prevalence of any suicide attempt was 8% and 3% in the lowest and highest income group, respectively. Before age 18, 0·011% girls and 0·016% boys had died by suicide. In conclusion, suicidal ideation and behaviour are common in adolescents and there is a substantial 'hidden number' of adolescents with suicide attempt. These results emphasize the need for early age suicide preventive interventions in community-settings e.g., school environments.

在许多国家,医院记录被用于识别自杀未遂事件,但并非所有的人在自杀未遂后都会到医院就诊,这就意味着存在 "隐性数字"。我们的目的是揭示丹麦青少年自杀意念、自杀计划、自杀未遂和自杀的发生率,包括未导致接触医院的自杀未遂。研究对象包括丹麦全国出生队列中参加了 18 年随访的参与者,并与全国登记数据建立了个人层面的联系。流行率是通过一个变量估算的,该变量具有相互排斥的类别,从无自杀倾向到自我报告的自杀意念、自杀计划、自杀未遂以及医院记录的自杀未遂,并根据性别和父母收入进行分层。隐性数字 "是指曾与医院接触和未与医院接触的自杀未遂事件之间的比率。在年龄均为 18 岁的 47 858 名参与者中,有 36% 的女孩和 28% 的男孩表示在其一生中至少有过一次自杀念头。此外,6% 的女孩和 3% 的男孩曾报告或记录过自杀未遂。在医院环境中,每有一次自杀未遂记录,就有两名女孩(比例为 1:2)和六名男孩(比例为 1:6)报告在未接触医院的情况下企图自杀。在最低收入组和最高收入组中,自杀未遂的发生率分别为 8%和 3%。在 18 岁之前,0-011% 的女孩和 0-016% 的男孩死于自杀。总之,自杀意念和行为在青少年中很常见,有自杀企图的青少年 "隐性人数 "很多。这些结果表明,有必要在社区环境(如学校环境)中采取早期自杀预防干预措施。
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引用次数: 0
The global prevalence of mental health disorders among runaway and homeless youth: A meta-analysis. 全球离家出走和无家可归青少年的心理健康障碍患病率:荟萃分析。
IF 6 2区 医学 Q1 PEDIATRICS Pub Date : 2025-02-01 Epub Date: 2024-07-12 DOI: 10.1007/s00787-024-02519-2
Bahram Armoon, Amir Ghadipasha, Rasool Mohammadi, Alain Lesage, Javad Harooni, Mark D Griffiths

A meta-analysis was performed to identify the pooled prevalence of mental health disorders (MHDs) among runaway and homeless youth (RHY). Relevant studies published between December 1, 1985, and October 1, 2023, were identified in the PubMed, Scopus, Web of Science, and Cochrane Library databases. A preliminary screening of 11,266 papers resulted in the inclusion of 101 studies. The pooled-prevalence estimates were obtained using a random-effects model. The findings showed varying lifetime prevalence rates of MHDs: 47% (conduct disorders and psychological distress), 43% (depression), 34% (major depressive disorders), 33% (post-traumatic stress disorder), 27% (personality disorders), 25% (attention-deficit/hyperactivity disorder), 23% (bipolar disorders), 22% (anxiety), 21% (oppositional defiant disorders), 15% (anorexia), 15% (adjustment disorders), 14% (dysthymia), 11% (schizophrenia), 9% (obsessive-compulsive disorders), and 8% (gambling disorder). The current prevalence rates were: 31% (depression), 23% (major depressive disorder), 23% (anxiety), 21% (post-traumatic stress disorder), 16% (attention-deficit/hyperactivity disorder), 15% (bipolar disorder), 13% (personality disorders), 13% (oppositional defiant disorders), 8% (schizophrenia), and 6% (obsessive-compulsive disorders). Regular screening and the implementation of evidence-based treatments and the promotion of integration and coordination between mental health services for adolescent minors and young adults with other service systems are recommended.

我们进行了一项荟萃分析,以确定离家出走和无家可归青少年(RHY)中精神健康失调(MHD)的总体患病率。在 PubMed、Scopus、Web of Science 和 Cochrane Library 数据库中查找了 1985 年 12 月 1 日至 2023 年 10 月 1 日期间发表的相关研究。经过对 11,266 篇论文的初步筛选,最终纳入了 101 项研究。采用随机效应模型得出了汇总流行率估计值。研究结果表明,儿童多动症的终生患病率各不相同:47%(行为障碍和心理困扰)、43%(抑郁症)、34%(重度抑郁症)、33%(创伤后应激障碍)、27%(人格障碍)、25%(注意力缺陷/多动症)、23%(双相情感障碍)、22%(焦虑症)、21%(对立违抗障碍)、15%(厌食症)、15%(适应障碍)、14%(癔症)、11%(精神分裂症)、9%(强迫症)和 8%(赌博障碍)。目前的患病率为31%(抑郁症)、23%(重度抑郁症)、23%(焦虑症)、21%(创伤后应激障碍)、16%(注意力缺陷/多动障碍)、15%(双相情感障碍)、13%(人格障碍)、13%(对立违抗障碍)、8%(精神分裂症)和 6%(强迫症)。建议定期进行筛查,实施循证治疗,促进未成年人和青少年精神健康服务与其他服务系统的整合与协调。
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