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A rare cause of stricture and ulcer in the colon: Chronic graft versus host disease 引起结肠狭窄和溃疡的罕见原因:慢性移植物抗宿主病
Pub Date : 2021-08-25 DOI: 10.17941/agd.980428
O. Coşkun, D. Yılmaz, F. Özen, M. Çapraz
Often during routine gastroenterology examinations, ulcers and strictures in the colon and small intestine are encountered in patients. Differential diagnosis of ulcers in these patients may not always be easy. Graft-versushost disease (GVHD) is a serious complication that can be life-threatening after allogeneic bone marrow transplantation (1). Since the introduction of modern immunosuppressive treatment regimens, clinical symptoms, radiographic and histological findings are rarely seen in chronic graft-versus-host disease (CGVHD) (2). However, CGVHD patients often present with various gastrointestinal symptoms such as esophageal reflux, dysphagia, bloating, weight loss, and diarrhea (2). Edema, erythema, diffuse polypoid lesions, multiple ulcers, and strictures in the mucosa can be observed in the endoscopic examination of intestinal GVHD (3).
通常在常规胃肠检查中,患者会遇到结肠和小肠溃疡和狭窄。这些患者的溃疡鉴别诊断可能并不总是容易的。移植物抗宿主病(GVHD)是同种异体骨髓移植后可能危及生命的严重并发症(1)。自从引入现代免疫抑制治疗方案以来,慢性移植物抗宿主病(CGVHD)的临床症状、影像学和组织学表现都很少见(2)。然而,CGVHD患者经常出现各种胃肠道症状,如食管反流、吞咽困难、腹胀、体重减轻和腹泻(2)。内镜下检查肠道GVHD可观察到黏膜红斑、弥漫性息肉样病变、多发溃疡和狭窄(3)。
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引用次数: 0
Laparoskopik cerrahide izoperistaltik intra-korporeal çift lineer stapler anastomoz: Erken oral beslenme; hızlı, kolay ve güvenilir teknik
Pub Date : 2021-08-25 DOI: 10.17941/agd.980422
Erol Pi̇şki̇n, Volkan Oter, Muhammet Kadri Çolakoğlu, Yigit Mehmet Ozgun, O. Aydin, E. Bostanci
Background and Aims: Minimally invasive surgery is associated with short-term recovery and better functional results in gastrointestinal sys-tem cancer surgery. It is applied in gastric and colon cancer surgery without compromising long-term oncological results. This study exam- ines patients who underwent anastomosis with the double linear stapler technique with isoperistaltic intracorporeal ileocolic and isoperistaltic colocolic anastomosis after laparoscopic radical distal Billroth 2 and laparoscopic right-left hemicolectomy. Material and Method: Thirteen patients who underwent anastomosis with the double linear stapler technique in our clinic between December 2019 and March 2021 were included in this study. All procedures were performed entirely laparoscopically, and anastomoses were completed intracorporeally with the assistance of a stapler. Results: The mean age of 13 patients in whom we performed the described anastomosis was 51.31 ± 16.84 years. Ten (76.9%) patients were male, and three (23.1%) were female. The median duration of the anastomosis was 12.38 ± 3.09 minutes. The median operation time was 13 minutes (min-max) (8–19 minutes). While no perioperative complications developed in 12 (92.3%) patients during anastomosis, perioperative intraluminal hemorrhage was observed in one (7.7%) patient. This hemorrhage was treated medically with fol-low-up. No relaparotomy was required for any patient. Conclusion: This stapler anastomosis technique can be performed quickly and easily in the reconstruction phase after laparoscopy. We think it can be done safely concerning anastomotic leakage.
背景与目的:微创手术在胃肠道肿瘤手术中具有短期恢复和较好的功能效果。它被应用于胃癌和结肠癌手术,而不会影响长期的肿瘤结果。本研究对腹腔镜下根治性远端Billroth 2和腹腔镜左右半结肠切除术后行双线吻合器吻合、肠腔内等径回结肠和肠腔内等径结肠吻合的患者进行了研究。材料与方法:选取2019年12月至2021年3月在我院行双线吻合器吻合术的13例患者作为研究对象。所有手术完全在腹腔镜下进行,吻合在吻合器的协助下在体内完成。结果:13例患者的平均年龄为51.31±16.84岁。男性10例(76.9%),女性3例(23.1%)。吻合时间中位数为12.38±3.09分钟。中位手术时间13分钟(min-max)(8-19分钟)。12例(92.3%)患者在吻合过程中未出现围手术期并发症,1例(7.7%)患者出现围手术期腔内出血。该出血经随访治疗。所有患者均无需再开腹手术。结论:吻合器吻合术可在腹腔镜术后重建阶段快速简便地进行吻合术。对于吻合口漏,我们认为是安全的。
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引用次数: 0
Atypically located spider angioma 位置不典型的蜘蛛血管瘤
Pub Date : 2021-05-14 DOI: 10.17941/AGD.931889
Şehmus Ölmez, B. Sarıtaş, Çisem Kzildağ, M. Mülayim
To the Editor, A spider angioma or spider naevus is a type of telangiectasis found slightly beneath the skin surface, often containing a central arteriole and many small vessels which radiate outwards like a spider's web. Applying pressure to the center of the lesion leads to fading of the lesion. Spider angioma is a common presentation of liver cirrhosis, especially alcoholic cirrhosis. Spider angiomas are found only in the distribution of the superior vena cava, and are thus commonly found on the face, neck, upper chest and upper arm. Spider angioma is rarely observed on hand (1, 2). Here, we report a a very rare case with spider angioma on back of hand. A 54-year-old male patient admitted to our clinic with icterus and ascites. The patient had a diagnosis of alcoholic liver cirrhosis one month before. On physical examination, he had icterus and ascites. He had spider angiomas on his back, neck and on the back of his right hand, just proximal to second metacarpophalangeal joint (Figure 1). The patient’s Child Turcotte Pugh score (CTP) and model for end stage liver disease (MELD) scores were 12 and 22, respectively. Abdomen ultrasound showed cirrhosis with massive ascites. Endoscopy revealed grade 1 esophageal varices and portal hypertensive gastropathy. The patient gave written consent regarding this article. Spider angioma appears frequently in alcoholic cirrhotic or noncirrhotic alcoholic liver diseases with deuteriation of liver functions. Although, the exact cause of SA is not known, there have been many theories of possible etiologic factors such as disturbance of sex hormones (increased level of luteinizing hormone, decreased level of testosterone and a higher estradiol/testosterone ratio), angiogenesis, vasodilation, alcohol abuse, hyperdynamic circulation state, and liver dysfunction[3, 4]. The number and size of SA are correlated with the degree of liver disease (1, 3, 4). Our patient was a heavy drinker and had alcoholic liver cirrhosis with high CTP and MELD score. Although, our patient had multiple telangiectasias, it is a very rare finding of SA, observed on back of hand.
蜘蛛血管瘤或蜘蛛痣是一种毛细血管扩张,发现于皮肤表面下,通常包含一个中心小动脉和许多像蜘蛛网一样向外辐射的小血管。对病灶中心施加压力会导致病灶褪色。蜘蛛血管瘤是肝硬化的常见表现,尤其是酒精性肝硬化。蜘蛛状血管瘤仅见于上腔静脉分布,因此常见于面部、颈部、上胸部和上臂。蜘蛛状血管瘤很少在手部观察到(1,2)。在这里,我们报告一个非常罕见的手背蜘蛛状血管瘤病例。一位54岁男性患者因黄疸和腹水入院。患者一个月前被诊断为酒精性肝硬化。经体格检查,他有黄疸和腹水。患者的背部、颈部、右手背部、第二掌指关节近端有蜘蛛血管瘤(图1)。患者的Child Turcotte Pugh评分(CTP)和终末期肝病模型(MELD)评分分别为12分和22分。腹部超声显示肝硬化伴大量腹水。内镜检查显示1级食管静脉曲张和门脉高压性胃病。病人对这篇文章给予了书面同意。蜘蛛血管瘤常见于酒精性肝硬化或非肝硬化酒精性肝病伴肝功能恶化。虽然SA的确切病因尚不清楚,但有许多可能的病因理论,如性激素紊乱(黄体生成素水平升高、睾酮水平降低和雌二醇/睾酮比升高)、血管生成、血管舒张、酗酒、高动力循环状态和肝功能障碍[3,4]。SA的数量和大小与肝脏疾病的程度相关(1,3,4)。我们的患者是重度饮酒者,患有酒精性肝硬化,CTP和MELD评分较高。虽然,我们的病人有多个毛细血管扩张,这是一个非常罕见的发现SA,观察到手背。
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引用次数: 0
Chilaiditi sendromu ve mide kanseri
Pub Date : 2021-05-14 DOI: 10.17941/AGD.931870
Serdar Özdemir, Abuzer Ozkan
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引用次数: 1
Hepatitis C Virus Epidemiology in Yemen: Systematic Review 也门丙型肝炎病毒流行病学:系统评价
Pub Date : 2021-05-04 DOI: 10.17941/AGD.923259
A. Almahbashi
Results: Forty-nine (49) studies were matching the inclusion and exclusion criteria from the four databases. After analyzing these 49 studies we found that in the general group of the population the prevalence was ranged between 0.07%-8.5%. Where the highest prevalence was in pregnant women (up to 8.5%) then the public (up to 6%) then blood donors and children up to 3% and 2.8% respectively. In the intermediate-risk group, hepatitis C virus infection prevalence was ranged between 1.03%-3.5% where all population was from the health department workers. In the high-risk group, the range was between 6.4%-62.7%, and the highest prevalence was recorded in liver disease patients. In the patient’s group the range of hepatitis C virus infection prevalence was between 0%-46%, while the sickle cell anemia patients were the lowest prevalence the chronic renal failure patients had the highest prevalence. Conclusion: This systemic review demonstrates a high prevalence of hepatitis C infection in Yemen. There is also a need to expand the scope of research and pay attention to new research groups and other cities to get a more comprehensive idea of the prevalence of the hepatitis C virus in Yemen.
结果:49项研究符合四个数据库的纳入和排除标准。在分析这49项研究后,我们发现在人群的一般组中患病率在0.07%-8.5%之间。在孕妇中患病率最高(高达8.5%),其次是公众(高达6%),然后是献血者和儿童,分别高达3%和2.8%。在中等危险人群中,丙型肝炎病毒感染率在1.03%-3.5%之间,所有人群均为卫生部门工作人员。在高危人群中,患病率范围在6.4%-62.7%之间,其中肝病患者的患病率最高。患者组丙型肝炎病毒感染率在0% ~ 46%之间,镰状细胞性贫血患者最低,慢性肾衰竭患者最高。结论:本系统综述显示也门丙型肝炎感染的高流行率。还需要扩大研究范围,并注意新的研究小组和其他城市,以便更全面地了解也门丙型肝炎病毒的流行情况。
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引用次数: 0
Mide hiperplastik polipleri ve öncül lezyonlarının değerlendirilmesi
Pub Date : 2021-04-28 DOI: 10.17941/AGD.927776
Rıfat Peksöz, Ali Mizrak
Giris ve Amac: Mide poliplerinin yaklasik %75-90 kadarini hiperplastik polipler olusturur. Kronik inflamasyon nedenli epitelin asiri rejenerasyonuna bagli, foveolar hiperplazi ve kronik gastrit sonrasinda bu oncul lezyonlardan hiperplastik polipler olusur. Bu calismada mide hiperplastik polipler ve oncul lezyonlarinin Helicobacter pylori ile iliskisi ve bu lezyonlarin intestinal metaplazi, atrofi durumlarinin literatur bilgileri esliginde tartisilmasi amaclanmistir. Gerec ve Yontem: Mus Devlet Hastanesi Endoskopi unitesinde Ocak 2016-Ocak 2020 tarihleri arasinda ozofagogastroduodenoskopi yapilan 7903 hastadan endoskopik gorunumu polipoid yapida olan 172 hastanin histopatolojileri degerlendirildi. Hastalarin yasi, cinsiyeti, basvuru sikâyeti, polipoid gorunumlu lezyonun yeri, lezyonlarin histopatolojik tipi kaydedildi. Bulgular: 172 hastaya polipektomi yapildi. Hastalarin 71’i erkek (%41.2), 101’i kadin (%58.8) olup, yas ortalamalari 49.4 ± 15 (19-83) yildi. Hastalar reaktif polipoid lezyonlar; foveolar hiperplazi 57 hasta, kronik gastrit 53 hasta ve gercek polipoid 62 hasta (en sik hiperplastik polip 47 hasta %75) olarak iki gruba ayrildi. Polipoid gorunumlu lezyonlar en fazla antrumda lokalize idi. Hastalarin basvuru sikayeti her iki grupta en fazla dispepsi idi. Gercek polip lezyonlarinin capi, reaktif polipoid lezyonlarin capindan istatistiksel olarak buyuk saptandi (p 0.05). Sonuc: Hiperplastik polipler ve oncul lezyonlarinin prekanseroz durumlar olan atrofi ve intestinal metaplazi oranlari arasinda anlamli fark saptanmamistir. Bu yuzden endoskopide saptanan lezyonlardan tani ve displazinin varligini saptamak icin biyopsi alinmali ya da eksize edilmeli ve Helicobacter pylori saptanan hastalar tedavi edilmelidir.
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引用次数: 0
Cerrahi prosedürler öncesi anti-HCV taraması: Hastalar yeterince bilgi sahibi mi?
Pub Date : 2021-04-28 DOI: 10.17941/AGD.930893
Nilay Daniş, A. Arslan, Murat Abdullah Buyruk, Fulya Günşar, A. Zeytinoğlu, İ. Altuğlu, U. Akarca
Giris ve Amac: Direkt etkili anti viral ilaclarin kullanilmasiyla, hepatit C virusu enfeksiyonunun tedavisinde basari orani %100’e yaklasmistir. Bununla birlikte, bircok hasta teshis konulmayi beklemektedir. Biz mevcut calismada cerrahi oncesi hepatit C virusu taramasi yapilan hastalarda anti-hepatit C virusu ve hepatit C virus-RNA pozitifliginin prevalansini belirlemeyi ve hastaligindan habersiz olan hastalarin oranini arastirmayi amacladik. Gerec ve Yontem: 2012-2015 yillari arasinda cerrahi kliniklerinde anti-hepatit C virusu pozitif saptanan hastalar, hepatit C virus-RNA pozitifligi ve tedavi gecmisi acisindan arastirildi. Hepatit C virus-RNA pozitifligi acisindan hastane kayitlari tarandi. Tedavi bilgilerine Medula Sisteminden (Sosyal Guvenlik Sisteminden entegre bir veri tabani) ulasildi. Tedavisiz anti-hepatit C virusu pozitif hastalara telefonla pozitiflikten haberdar olup olmadiklari soruldu. Bulgular: 4 yil boyunca 19627 hasta anti-hepatit C virusu pozitifligi acisindan tarandi. 158 hastada (%0.8) anti-hepatit C virusu pozitif bulundu (76 erkek, 82 kadin; yas: 58.2 ± 17.6). Hepatit C virus-RNA 83 hastada bakilmisti, 75 hastada hepatit C virus-RNA testi yoktu. Ulasilabilen 58 hastanin sadece 14’u anti-hepatit C virusu pozitif oldugunu biliyordu. Diger 44 hasta gastroenteroloji veya enfeksiyon hastaliklari polikliniklerine basvurmalari konusunda uyarildi. Sonuc: Cerrahi girisim uygulanan 19627 hastanin %0.8’inde anti-hepatit C virusu genel Turkiye nufusuna benzer oranda pozitif bulunmustur. Hastalarin neredeyse yarisinda hepatit C virus-RNA test edilmemis ve cogu hasta hepatit C virusu-RNA’nin test edilmesi ve izlenmesi gerektigi bilgisine sahip degildir. Anti- hepatit C virusunun cerrahi oncesi taranmasi yeni hastalarin tespiti acisindan yetersiz bulunmustur.
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引用次数: 1
Massive gastrointestinal bleeding due to rectovaginal fistula: A rare case report 直肠阴道瘘致消化道大出血1例
Pub Date : 2021-01-11 DOI: 10.17941/agd.1052909
Şehmus Ölmez, S. Baş, Nevin AKÇAER ÖZTÜRK, O. Dilek, B. Sarıtaş
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引用次数: 0
Dieulafoy lezyonu tanılı hastalarda endoskopik tedavi başarısı ve takip sonuçları
Pub Date : 2020-12-25 DOI: 10.17941/agd.836616
Göktuğ Şirin, Ali Duman, Hasan Yılmaz, S. Balci, Ayça Haktanir, Emrullah Dengeşik, Kenan Özendi, Altay Çelebi, Sadettin Hülagü
{"title":"Dieulafoy lezyonu tanılı hastalarda endoskopik tedavi başarısı ve takip sonuçları","authors":"Göktuğ Şirin, Ali Duman, Hasan Yılmaz, S. Balci, Ayça Haktanir, Emrullah Dengeşik, Kenan Özendi, Altay Çelebi, Sadettin Hülagü","doi":"10.17941/agd.836616","DOIUrl":"https://doi.org/10.17941/agd.836616","url":null,"abstract":"","PeriodicalId":118745,"journal":{"name":"Akademik Gastroenteroloji Dergisi","volume":"269 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121984537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malign ile benign portal ven trombozunun ayrımında 3 Tesla manyetik rezonans görüntülemede difüzyon ağırlıklı görüntülemenin rolü
Pub Date : 2020-12-25 DOI: 10.17941/agd.839289
Ezgi Guler, Egemen Öztürk, M. Yuksel, Timur Köse, Mustafa Harman, A. Özütemiz, Nevra Elmas
Background and Aims: The purpose of this study was to evaluate the use of diffusion-weighted imaging at 3 Tesla magnetic resonance imaging in differentiating malignant from benign portal vein thrombo- sis. Materials and Method: Abdominal magnetic resonance imaging examinations obtained at 3 Tesla magnetic resonance imaging unit be- tween January 2011 and December 2016 were reviewed retrospective-ly to identify the cases with portal vein thrombosis. Portal vein thrombosis was considered malignant if it enhanced ≥15% on arterial phase contrast-enhanced images relative to precontrast images. Moreover, the diameter of the portal vein involved with the thrombus was mea-sured, and the signal intensity of the portal vein thrombosis on diffu- sion-weighted images was recorded. The apparent diffusion coefficient values for malignant and benign portal vein thrombosis were calculated by two independent readers. Results: In this study, 23 patients with malignant portal vein thrombosis [19 men, 4 women; median age 63 years (52–83)] and 14 patients with benign portal vein thrombosis (5 men, 9 women; median age 65 years 47–82)] were identified. Statis-tically significant difference was observed in signal intensity on diffu-sion-weighted images (p < 0.05) between malignant and benign portal vein thrombosis. The mean apparent diffusion coefficient values for malignant portal vein thrombosis were significantly lower than those for benign portal vein thrombosis (p < 0.05). Furthermore, there was a high agreement on the calculation of apparent diffusion coefficient values (R 1 : 0.948) between the two readers. Sensitivity and specifici- ty values were both 100% for the diagnosis of malignant portal vein thrombosis when the apparent diffusion coefficient value was ≤1.4 x 10 –3 mm 2 /s. Conclusion: Thus, diffusion-weighted imaging at 3 Tesla magnetic resonance imaging is beneficial for the differentiation of malignant and benign portal vein thrombosis. Characterization of portal vein thrombosis using its signal intensity on diffusion-weighted images and apparent diffusion coefficient values is important in patients in whom the use of contrast media is contraindicated.
背景和目的:本研究的目的是评价3特斯拉磁共振弥散加权成像在鉴别门静脉血栓形成的良恶性中的应用。材料与方法:回顾性分析2011年1月至2016年12月在3台特斯拉磁共振成像仪进行的腹部磁共振成像检查,确定门静脉血栓形成病例。如果门静脉血栓形成在动脉期增强图像上相对于造影前图像增强≥15%,则认为门静脉血栓形成是恶性的。测量受累门静脉的直径,记录门静脉血栓在弥散加权图像上的信号强度。恶性和良性门静脉血栓的表观扩散系数值由两位独立的阅读者计算。结果:本组23例恶性门静脉血栓患者[男19例,女4例;中位年龄63岁(52 ~ 83岁)],良性门静脉血栓形成14例(男5例,女9例;中位年龄65岁(47-82岁)]。恶性门静脉血栓形成与良性门静脉血栓形成弥散加权像信号强度差异有统计学意义(p < 0.05)。恶性门静脉血栓的平均表观扩散系数值明显低于良性门静脉血栓(p < 0.05)。此外,在表观扩散系数的计算上,两种读者有很高的一致性(r1: 0.948)。当表观扩散系数≤1.4 × 10 - 3mm2 /s时,诊断门静脉恶性血栓的敏感性和特异性均为100%。结论:3特斯拉磁共振弥散加权成像有利于门静脉血栓的良恶性鉴别。门静脉血栓形成的信号在弥散加权图像上的信号强度和表观弥散系数值在使用造影剂禁忌的患者中是很重要的。
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引用次数: 0
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