{"title":"Zosteriform cutaneous metastasis: a case report of ovarian neoplasms.","authors":"Xinjie Deng, Yan Chen, Zhenchun Lei, Yunsheng Xu","doi":"10.1684/ejd.2024.4708","DOIUrl":"10.1684/ejd.2024.4708","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 3","pages":"332-334"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The interplay between dermocosmetics and pharmacotherapy in the management of scalp seborrheic dermatitis.","authors":"Lidia Rudnicka","doi":"10.1684/ejd.2024.4715","DOIUrl":"10.1684/ejd.2024.4715","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 S1","pages":"3"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thilo Gambichler, Mira H Sandersfeld, Jörg Schaller, Thorsten Wiech, Tom Zimmermann, Fedai Özcan, Laura Susok
{"title":"Adult Henoch-Schönlein purpura complicated by IgA-nephritis in a patient with mantle cell lymphoma and Graves disease.","authors":"Thilo Gambichler, Mira H Sandersfeld, Jörg Schaller, Thorsten Wiech, Tom Zimmermann, Fedai Özcan, Laura Susok","doi":"10.1684/ejd.2024.4692","DOIUrl":"10.1684/ejd.2024.4692","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 3","pages":"318-320"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Onychomycosis, a fungal nail infection, is primarily caused by dermatophytes, yeasts, and non-dermatophyte moulds (NDMs). The incidence of this disease and the predominance of specific pathogens vary across different regions and evolve. This study aimed to elucidate the epidemiology of onychomycosis and the pattern of causative pathogens in Beijing, and to ascertain the in vitro antifungal susceptibility profiles of Trichophyton rubrum against itraconazole (ITR), terbinafine (TER), and fluconazole (FLU). Involving 245 patients of onychomycosis with positive fungal culture results, the study implemented internal transcribed spacer (ITS) sequencing of ribosomal DNA (rDNA) on all collected samples. The mean age of the participants was 37.93 ± 13.73 years, with a male-to-female ratio of 1.53:1. The prevalence of toenail infections was significantly higher than that of fingernails. Distal and lateral subungual onychomycosis (DLSO) were the most frequent clinical classifications. PCR results indicated that dermatophytes were the most prevalent pathogens, followed by yeasts and NDMs, among which T. rubrum was the most dominant dermatophyte. TER demonstrated high sensitivity to T. rubrum. However, in clinical settings, some patients with onychomycosis exhibit a poor response to TER treatment. The relationship between in vitro antifungal sensitivity and clinical effectiveness is complex, and understanding the link between in vitro MIC values and clinical efficacy requires further investigation.
甲癣是一种指甲真菌感染，主要由皮真菌、酵母菌和非皮真菌霉菌（NDM）引起。这种疾病在不同地区的发病率和特定病原体的占主导地位各不相同，并在不断演变。本研究旨在阐明北京地区甲癣的流行病学和致病病原体的模式，并确定红癣毛癣菌（Trichophyton rubrum）对伊曲康唑（ITR）、特比萘芬（TER）和氟康唑（FLU）的体外抗真菌药敏谱。该研究涉及 245 名真菌培养结果呈阳性的甲癣患者，对所有采集的样本进行了核糖体 DNA (rDNA) 内部转录间隔 (ITS) 测序。参与者的平均年龄为（37.93 ± 13.73）岁，男女比例为 1.53:1。趾甲感染率明显高于指甲感染率。远端和外侧甲下真菌病（DLSO）是最常见的临床分类。PCR 结果显示，皮癣菌是最常见的病原体，其次是酵母菌和 NDM，其中红癣菌是最主要的皮癣菌。TER 显示出对红癣菌的高度敏感性。然而，在临床环境中，一些甲癣患者对 TER 的治疗反应不佳。体外抗真菌敏感性与临床疗效之间的关系非常复杂，因此需要进一步研究体外 MIC 值与临床疗效之间的联系。
{"title":"Clinico-mycological study of onychomycosis and in vitro antifungal susceptibility of Trichophyton rubrum.","authors":"Xin Huang, Qian Wang, Qiu-Hong Yan, Sen Feng, Guo-Qiang Zhang, Xiao-Ying Yuan","doi":"10.1684/ejd.2024.4678","DOIUrl":"10.1684/ejd.2024.4678","url":null,"abstract":"<p><p>Onychomycosis, a fungal nail infection, is primarily caused by dermatophytes, yeasts, and non-dermatophyte moulds (NDMs). The incidence of this disease and the predominance of specific pathogens vary across different regions and evolve. This study aimed to elucidate the epidemiology of onychomycosis and the pattern of causative pathogens in Beijing, and to ascertain the in vitro antifungal susceptibility profiles of Trichophyton rubrum against itraconazole (ITR), terbinafine (TER), and fluconazole (FLU). Involving 245 patients of onychomycosis with positive fungal culture results, the study implemented internal transcribed spacer (ITS) sequencing of ribosomal DNA (rDNA) on all collected samples. The mean age of the participants was 37.93 ± 13.73 years, with a male-to-female ratio of 1.53:1. The prevalence of toenail infections was significantly higher than that of fingernails. Distal and lateral subungual onychomycosis (DLSO) were the most frequent clinical classifications. PCR results indicated that dermatophytes were the most prevalent pathogens, followed by yeasts and NDMs, among which T. rubrum was the most dominant dermatophyte. TER demonstrated high sensitivity to T. rubrum. However, in clinical settings, some patients with onychomycosis exhibit a poor response to TER treatment. The relationship between in vitro antifungal sensitivity and clinical effectiveness is complex, and understanding the link between in vitro MIC values and clinical efficacy requires further investigation.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 3","pages":"260-266"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin-Yi Hou, Shu-Lan Yao, Jing-Yu Wang, Jin Zhang, Fei-Fei Liu, Bin Lu
{"title":"Cutaneous Rosai-Dorfman-Destombes disease in a child: a case report and brief review.","authors":"Xin-Yi Hou, Shu-Lan Yao, Jing-Yu Wang, Jin Zhang, Fei-Fei Liu, Bin Lu","doi":"10.1684/ejd.2024.4710","DOIUrl":"10.1684/ejd.2024.4710","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 3","pages":"329-330"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"sQuiz your knowledge! Acral haemorrhagic macules and vesicles.","authors":"Bárbara V Granja, Diana Martins, Nuno P Gomes","doi":"10.1684/ejd.2024.4718","DOIUrl":"10.1684/ejd.2024.4718","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 3","pages":"343-344"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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