F. Martínez Soriano, A. Blasco-Serra, E. González-Soler, Salvador Hernández-Sánchez, Alfonso A. Valverde Navarro
Classical studies pointed out to a possible division of rodents’ pineal parenchyma in various regions and layers, also observing variations in nuclear sizes that could depend on luminosity cycles. The aim of this study is to analyze the morphological changes of nuclear sizes of pinealocytes that occur in the pineal gland of albino rats during different hours of the day, seasons and photoperiods, taking into account the different layers and regions. We studied differences on karyometric indices of pinealocytes of the peripheral (cortical) and central (medullary) layers of pineal gland in order to analyze the circadian and seasonal modifications, and establish whether these are indicative of functional differences between proximal, intermediate, and distal portions. Results showed that the total karyometric values of the distal area are clearly higher than those of the other two areas, and in turn those of the intermediate area are also significantly higher than those of the pars proximalis; and also, that there are significant differences between the peripheral and central karyometric indices of all the pineal regions analyzed. Moreover, there are significant evolutionary circadian, photophasic and seasonal differences between regions and the pineal layers analyzed.
{"title":"Topographic morphometry of the pineal gland of the rat. A 24-hours period, light-dark cycle and seasonal study","authors":"F. Martínez Soriano, A. Blasco-Serra, E. González-Soler, Salvador Hernández-Sánchez, Alfonso A. Valverde Navarro","doi":"10.52083/xdns9336","DOIUrl":"https://doi.org/10.52083/xdns9336","url":null,"abstract":"Classical studies pointed out to a possible division of rodents’ pineal parenchyma in various regions and layers, also observing variations in nuclear sizes that could depend on luminosity cycles. The aim of this study is to analyze the morphological changes of nuclear sizes of pinealocytes that occur in the pineal gland of albino rats during different hours of the day, seasons and photoperiods, taking into account the different layers and regions. We studied differences on karyometric indices of pinealocytes of the peripheral (cortical) and central (medullary) layers of pineal gland in order to analyze the circadian and seasonal modifications, and establish whether these are indicative of functional differences between proximal, intermediate, and distal portions. Results showed that the total karyometric values of the distal area are clearly higher than those of the other two areas, and in turn those of the intermediate area are also significantly higher than those of the pars proximalis; and also, that there are significant differences between the peripheral and central karyometric indices of all the pineal regions analyzed. Moreover, there are significant evolutionary circadian, photophasic and seasonal differences between regions and the pineal layers analyzed.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"189 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75012554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leflunomide is an antirheumatic drug commonly used by females, as this disease is common in females and there are chances of pregnancy while taking this medication in initial months of pregnancy this commonly prescribed drug lacks studies related to its teratogenic potential. Present study was conducted to know about its teratogenicity in mice embryos. Pregnant mice were exposed to Leflunomide by oral route on gestational days 6 to 11 either as single dose in one of the gestational days or continuous doses. The embryos were collected on day 19 of gestation, were measured and examined for external anomalies. Findings suggested that Leflunomide was embryo lethal when given as continuous dose as there were 100% resorption of embryos. In the single dose group, maximum resorptions were found when was given in early pregnancy. Other anomalies included malrotated limbs, open eyes, kinking of tails, defect in anterior abdominal wall and visceroptosis and anencephaly. these anomalies were noted in embryos exposed to leflunomide only on gestational days 7 and 8. The above findings suggest that leflunomide interferes with embryonic growth It also interferes with neural tube closure leading to anencephaly. Findings of open eyes and kinking tails suggest that the drug may affect epithelial and mesodermal growth. Leflunomide perhaps interferes with the lateral folding of the embryo leading to defect in the anterior abdominal wall and visceroptosis. The present study concludes that Leflunomide is teratogenic and embryolethal in mice and should be avoided in human pregnancy.
{"title":"Gross congenital abnormalities induced by leflunomide in mice embryos","authors":"K. Pandey, Nishtha K. Singh, A. Nayak, C. Mohanty","doi":"10.52083/wnei1659","DOIUrl":"https://doi.org/10.52083/wnei1659","url":null,"abstract":"Leflunomide is an antirheumatic drug commonly used by females, as this disease is common in females and there are chances of pregnancy while taking this medication in initial months of pregnancy this commonly prescribed drug lacks studies related to its teratogenic potential. Present study was conducted to know about its teratogenicity in mice embryos. Pregnant mice were exposed to Leflunomide by oral route on gestational days 6 to 11 either as single dose in one of the gestational days or continuous doses. The embryos were collected on day 19 of gestation, were measured and examined for external anomalies. Findings suggested that Leflunomide was embryo lethal when given as continuous dose as there were 100% resorption of embryos. In the single dose group, maximum resorptions were found when was given in early pregnancy. Other anomalies included malrotated limbs, open eyes, kinking of tails, defect in anterior abdominal wall and visceroptosis and anencephaly. these anomalies were noted in embryos exposed to leflunomide only on gestational days 7 and 8. The above findings suggest that leflunomide interferes with embryonic growth It also interferes with neural tube closure leading to anencephaly. Findings of open eyes and kinking tails suggest that the drug may affect epithelial and mesodermal growth. Leflunomide perhaps interferes with the lateral folding of the embryo leading to defect in the anterior abdominal wall and visceroptosis. The present study concludes that Leflunomide is teratogenic and embryolethal in mice and should be avoided in human pregnancy.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"45 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81142249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The dissection course plays a central role in teaching anatomy and body donors are also needed in clinical-anatomical courses. In order to reduce formaldehyde exposure of students, participants and staff during these courses, we employed fixation solutions with low formaldehyde content. In this study, we present two ethanol-based protocols, and elucidate their suitability for the dissection process and compliance with occupational exposure limits for formaldehyde and other hazardous substances. Body donors were fixed according to an ethanol- based fixation protocol for the dissection course or an ethanol-glycerin-based fixation protocol for specialist training courses. The quality of fixation was determined during the dissection process. Exposure to hazardous substances (formaldehyde, ethanol, 2-phenoxyethanol) was measured in a regular dissection course setting at different locations (room-related and person-related measurements), and exposure indices were calculated. The quality of fixation of both methods was good and fulfilled all requirements of the student dissection course and the specialist training courses, respectively. Exposure to all hazardous substances remained well below the exposure limits. Room-related air concentration measurements were 0.073/0.058 mg/m³ (2016/2017) for formaldehyde and 65/107 mg/m³ (2016/2017) for ethanol. Person-related measurements amounted to 0.107-0.229 mg/m³ for formaldehyde and 268- 388 mg/m³ for ethanol. Room-related and person- related concentrations of 2-phenoxyethanol remained below the detection limit. The ethanol-based embalming protocols presented here offer a good alternative for the different applications. The protocols are discussed regarding current regulations and further measures to reduce formaldehyde exposure.
{"title":"Measuring low formaldehyde exposure values in the dissection hall after embalming human body donors with ethanol-based fixation methods","authors":"Anke Schnapper-Isl, Frank Klose, A. Schmiedl","doi":"10.52083/cyoj3969","DOIUrl":"https://doi.org/10.52083/cyoj3969","url":null,"abstract":"The dissection course plays a central role in teaching anatomy and body donors are also needed in clinical-anatomical courses. In order to reduce formaldehyde exposure of students, participants and staff during these courses, we employed fixation solutions with low formaldehyde content. In this study, we present two ethanol-based protocols, and elucidate their suitability for the dissection process and compliance with occupational exposure limits for formaldehyde and other hazardous substances. Body donors were fixed according to an ethanol- based fixation protocol for the dissection course or an ethanol-glycerin-based fixation protocol for specialist training courses. The quality of fixation was determined during the dissection process. Exposure to hazardous substances (formaldehyde, ethanol, 2-phenoxyethanol) was measured in a regular dissection course setting at different locations (room-related and person-related measurements), and exposure indices were calculated. The quality of fixation of both methods was good and fulfilled all requirements of the student dissection course and the specialist training courses, respectively. Exposure to all hazardous substances remained well below the exposure limits. Room-related air concentration measurements were 0.073/0.058 mg/m³ (2016/2017) for formaldehyde and 65/107 mg/m³ (2016/2017) for ethanol. Person-related measurements amounted to 0.107-0.229 mg/m³ for formaldehyde and 268- 388 mg/m³ for ethanol. Room-related and person- related concentrations of 2-phenoxyethanol remained below the detection limit. The ethanol-based embalming protocols presented here offer a good alternative for the different applications. The protocols are discussed regarding current regulations and further measures to reduce formaldehyde exposure.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"92 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77699723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Moreno-Salinas, J. Treviño-Gonzalez, C. Casas-Murillo, K. Aguilar-Morales, R. Pinales-Razo, Miguel De La Parra-Marquez, Rodrigo E Elizondo-Omaña, S. Guzmán-López, A. Quiroga-Garza
The buccal fat pad (BFP), is an adipose tissue located in the cheek, with complex morphology. Oral bichatectomy is a frequent aesthetic procedure with possible complications. Our objective was to determine the volume and its relationship with the upper 2nd molar and the facial artery (FA). A cross-sectional, observational study was performed. Computed tomography was used to obtain 3D images to determine volume, length, and width. Distances from the 2nd molar to each extension, and the nearest distance to the FA were measured. A total of 106 BFP (70 male) were included. The mean age was 51±21. The mean volume, length, and width were 13.8±5.4 ml, 72.9±10.7 mm, and 21.4±5.6 mm, respectively. The BFP extends mainly cephalically and caudally from the second molar, reaching upto 8.5 cm and 32 ml. The mean distance between the second molar and FA was 12.9 mm, but as close as 3 mm. The FA had a mean distance of 2.1mm to the nearest BFP extension, with 42.5% in intimate contact, and another 9.4% crossing the center of the masseter extension. There were no statistically significant differences between sexes. The BFP has a dynamic shape with highly variable size and volume. The FA is often at risk of damage during procedures due to proximity
{"title":"Anatomy of the buccal fat pad for structures at risk during bichatectomy","authors":"A. Moreno-Salinas, J. Treviño-Gonzalez, C. Casas-Murillo, K. Aguilar-Morales, R. Pinales-Razo, Miguel De La Parra-Marquez, Rodrigo E Elizondo-Omaña, S. Guzmán-López, A. Quiroga-Garza","doi":"10.52083/nsqz9800","DOIUrl":"https://doi.org/10.52083/nsqz9800","url":null,"abstract":"The buccal fat pad (BFP), is an adipose tissue located in the cheek, with complex morphology. Oral bichatectomy is a frequent aesthetic procedure with possible complications. Our objective was to determine the volume and its relationship with the upper 2nd molar and the facial artery (FA). A cross-sectional, observational study was performed. Computed tomography was used to obtain 3D images to determine volume, length, and width. Distances from the 2nd molar to each extension, and the nearest distance to the FA were measured. A total of 106 BFP (70 male) were included. The mean age was 51±21. The mean volume, length, and width were 13.8±5.4 ml, 72.9±10.7 mm, and 21.4±5.6 mm, respectively. The BFP extends mainly cephalically and caudally from the second molar, reaching upto 8.5 cm and 32 ml. The mean distance between the second molar and FA was 12.9 mm, but as close as 3 mm. The FA had a mean distance of 2.1mm to the nearest BFP extension, with 42.5% in intimate contact, and another 9.4% crossing the center of the masseter extension. There were no statistically significant differences between sexes. The BFP has a dynamic shape with highly variable size and volume. The FA is often at risk of damage during procedures due to proximity","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"525 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73540309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
While anatomy has been taught by means of traditional methods for centuries, today anatomy education methods are developing with various digital educational resources. Therefore, determining the trends of publications on the use of technology in anatomy education can provide a roadmap for future studies on this topic. This study aims to conduct a bibliometric analysis of the documents about technology in anatomy education. Using the bibliometric analysis method, 437 documents between 1987 and 2021 were included in the study. Publications in journals indexed in Web of Science were reviewed in terms of the country, journal, citation, year, author, keywords, co-authorship, co-occurrence, and co-citation. The H-index value of the publications was 47, and the total number of citations was 8501. The publications highlight an exponential increase in the last few years, as well as the prominence of a particular journal and countries such as the USA, England or Australia. Wilson TD was the most prolific author in the field. According to the co-occurrence analysis, it is observed that the terms “gross anatomy education”, and “medical education” are frequently used by the authors. In the last few years, 3D printing, virtual reality, augmented reality and social media were selected in anatomy education. This study identified the main research hotspots related to the use of technology in anatomy education. The findings can also help provide new directions and ideas for future research.
几个世纪以来，解剖学一直是通过传统方法进行教学的，而今天，解剖学教育方法正在随着各种数字化教育资源的发展而发展。因此，确定在解剖学教育中使用技术的出版物的趋势可以为该主题的未来研究提供路线图。本研究旨在对解剖学教学中有关技术的文献进行文献计量学分析。采用文献计量分析方法，将1987 - 2021年间的437篇文献纳入研究。根据国家、期刊、引文、年份、作者、关键词、合著、共现、共被引等方面对Web of Science收录期刊的出版物进行了综述。论文的h指数值为47，总被引次数为8501。这些出版物强调了过去几年的指数增长，以及特定期刊和美国、英国或澳大利亚等国家的突出地位。威尔逊是该领域最多产的作家。根据共现性分析，作者经常使用“大体解剖教育”和“医学教育”这两个词。在过去的几年里，解剖学教育选择了3D打印、虚拟现实、增强现实和社交媒体。本研究明确了技术在解剖学教育中应用的主要研究热点。这些发现也有助于为未来的研究提供新的方向和思路。
{"title":"Bibliometric and visualized analysis of global research on technology in anatomy education from 1987 to 2021","authors":"Y. E. Kundakcı, E. Atay","doi":"10.52083/hnny3374","DOIUrl":"https://doi.org/10.52083/hnny3374","url":null,"abstract":"While anatomy has been taught by means of traditional methods for centuries, today anatomy education methods are developing with various digital educational resources. Therefore, determining the trends of publications on the use of technology in anatomy education can provide a roadmap for future studies on this topic. This study aims to conduct a bibliometric analysis of the documents about technology in anatomy education. Using the bibliometric analysis method, 437 documents between 1987 and 2021 were included in the study. Publications in journals indexed in Web of Science were reviewed in terms of the country, journal, citation, year, author, keywords, co-authorship, co-occurrence, and co-citation. The H-index value of the publications was 47, and the total number of citations was 8501. The publications highlight an exponential increase in the last few years, as well as the prominence of a particular journal and countries such as the USA, England or Australia. Wilson TD was the most prolific author in the field. According to the co-occurrence analysis, it is observed that the terms “gross anatomy education”, and “medical education” are frequently used by the authors. In the last few years, 3D printing, virtual reality, augmented reality and social media were selected in anatomy education. This study identified the main research hotspots related to the use of technology in anatomy education. The findings can also help provide new directions and ideas for future research.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"127 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80243870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to reveal differences in the mandibular corpus and ramus measurements, volume (VOM), and gross weight of the mandible (GWOM) between the low and high gonial angles (L-GA and H-GA, respectively) in adult mandibles, and to evaluate the correlations between GAs and the measurement variables. Twenty-nine dried adult human complete dentate mandibles (L-GA ≤ 120°: 13 mandibles; H-GA: 125° ≥ GA: 16 mandibles) were measured using a lateral radiograph image-processing system, digital Vernier calipers, and an electric balance. The total length of the mandible (TLOM), corpus length (mental foramen– gonion [MeF’-Go’], mental foramen–mandibular foramen [MeF’-MaF’], and mandibular foramen–gonion [MaF’-Go’]), inter-ramus (bicondylar, bicoronion, and bigonion) widths (BiCoW, BiCorW, and BiGoW), GA width (GAW), condylar perpendicular height (CPH), the VOM, and GWOM were measured. Data were assessed using the exact binomial test, Mann–Whitney U test and Pearson’s correlation coefficient test. The MeF’- Go’ and MaF’-Go’, three inter-ramus widths, GAW, CPH, VOM, and GWOM in the L-GA group were significantly larger than those in the H-GA group. Significant negative correlations were found between GA size and multiple variables other than TLOM and BiCorW. Therefore, GA size was closely related to the enlarged morphometric dimensions of both the GA and the mandibular ramus in the posterior region of the mandibular corpus, as well as the volume and weight of the mandible, but it was not related to TLOM. These results indicate that the evaluation of GA size is useful for strategic dental treatment.
{"title":"Variations in corpus and ramus measurements based on gonial angles in adult complete dentate mandibles","authors":"Ken Hiratsuka, S. Osato","doi":"10.52083/awym4087","DOIUrl":"https://doi.org/10.52083/awym4087","url":null,"abstract":"This study aimed to reveal differences in the mandibular corpus and ramus measurements, volume (VOM), and gross weight of the mandible (GWOM) between the low and high gonial angles (L-GA and H-GA, respectively) in adult mandibles, and to evaluate the correlations between GAs and the measurement variables. Twenty-nine dried adult human complete dentate mandibles (L-GA ≤ 120°: 13 mandibles; H-GA: 125° ≥ GA: 16 mandibles) were measured using a lateral radiograph image-processing system, digital Vernier calipers, and an electric balance. The total length of the mandible (TLOM), corpus length (mental foramen– gonion [MeF’-Go’], mental foramen–mandibular foramen [MeF’-MaF’], and mandibular foramen–gonion [MaF’-Go’]), inter-ramus (bicondylar, bicoronion, and bigonion) widths (BiCoW, BiCorW, and BiGoW), GA width (GAW), condylar perpendicular height (CPH), the VOM, and GWOM were measured. Data were assessed using the exact binomial test, Mann–Whitney U test and Pearson’s correlation coefficient test. The MeF’- Go’ and MaF’-Go’, three inter-ramus widths, GAW, CPH, VOM, and GWOM in the L-GA group were significantly larger than those in the H-GA group. Significant negative correlations were found between GA size and multiple variables other than TLOM and BiCorW. Therefore, GA size was closely related to the enlarged morphometric dimensions of both the GA and the mandibular ramus in the posterior region of the mandibular corpus, as well as the volume and weight of the mandible, but it was not related to TLOM. These results indicate that the evaluation of GA size is useful for strategic dental treatment.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"42 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78705852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teratoma means “A malformed body part of a monster” in Greek. A cervical teratoma is a very rare congenital tumor in the neck. These tumors tend to be large, disfiguring masses – partly solid and partly fluid. They make it impossible for a newborn to breathe upon birth. Knowledge of basic embryology of the brachial apparatus is necessary to understand neck malformations and congenital abnormalities. Here, a recent observation of this exceptional case is described. A pregnant woman, gravida 2, presented with pain abdomen in the 37th week of gestation. A male, living baby was delivered by caesarean section. A well-defined mass was present in the anterior neck region. A diagnosis of giant congenital cervical teratoma with airway compromise was made. The baby was intubated but could not survive. The objective of this study is the significance of a thorough knowledge of anatomy and embryology to prevent any late diagnosis or misdiagnosis. This report aims to create awareness about embryological development of a fetus to enhance the clinical recognition of this rare disorder, to highlight their occurrence in our locale, and to reiterate the associated management challenges in resource-limited settings. The present case highlights the importance of regular antenatal checkups, with timely ultrasounds, so that such congenital defects can be diagnosed prenatally and their management can be planned accordingly.
{"title":"Congenital cervical teratoma – an amalgamation of embryology with clinical findings","authors":"Fariha Sabeen","doi":"10.52083/dhmy7841","DOIUrl":"https://doi.org/10.52083/dhmy7841","url":null,"abstract":"Teratoma means “A malformed body part of a monster” in Greek. A cervical teratoma is a very rare congenital tumor in the neck. These tumors tend to be large, disfiguring masses – partly solid and partly fluid. They make it impossible for a newborn to breathe upon birth. Knowledge of basic embryology of the brachial apparatus is necessary to understand neck malformations and congenital abnormalities. Here, a recent observation of this exceptional case is described. A pregnant woman, gravida 2, presented with pain abdomen in the 37th week of gestation. A male, living baby was delivered by caesarean section. A well-defined mass was present in the anterior neck region. A diagnosis of giant congenital cervical teratoma with airway compromise was made. The baby was intubated but could not survive. The objective of this study is the significance of a thorough knowledge of anatomy and embryology to prevent any late diagnosis or misdiagnosis. This report aims to create awareness about embryological development of a fetus to enhance the clinical recognition of this rare disorder, to highlight their occurrence in our locale, and to reiterate the associated management challenges in resource-limited settings. The present case highlights the importance of regular antenatal checkups, with timely ultrasounds, so that such congenital defects can be diagnosed prenatally and their management can be planned accordingly.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"4 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78964933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Keleş, Mustafa YILMAZ, C. Kadıyoran, D. A. Saygın
The deep femoral artery and its branches are vital for the arterial circulation of the lower extremity. The aim of the current study is to obtain morphometric and morphological data on the deep femoral artery and its branches and to investigate their clinical importance in the Turkish population. Morphometric measurements of the deep femoral artery and femoral artery were performed. The diameters of the femoral artery and deep femoral artery were measured in the axial plane. Classification was made according to the size of these diameters. A morphological classification was obtained by examining the variations of the deep femoral artery branches. The distance from the origin of the deep femoral artery to the midpoint of the inguinal ligament was 39.56 ± 8.52 mm, and the distances from the origin of the lateral circumflex femoral artery to the medial circumflex femoral artery were 17.15 ± 4.79 mm and 12.52 ± 4.58 mm, respectively. The study results show that there was a significant difference between genders in terms of the diameters measured. In the classification made by using the diameters, Type D (39%) had the highest rate, whereas Type C had the lowest rate (7.3%). According to the morphological classification, Type I (52.1%) was the most common in all individuals, and Type V and Type VII (2.3%) were the least common. Our study includes both morphometric and morphological information about the femoral artery and deep femoral artery of the Turkish population. We consider that the current study will be useful for cardiologists, interventional radiologists, orthopedists, and regional surgeons in clinical practice.
{"title":"Deep femoral artery branching by MDCT in a Turkish population and its potential clinical implications","authors":"A. Keleş, Mustafa YILMAZ, C. Kadıyoran, D. A. Saygın","doi":"10.52083/xsan1528","DOIUrl":"https://doi.org/10.52083/xsan1528","url":null,"abstract":"The deep femoral artery and its branches are vital for the arterial circulation of the lower extremity. The aim of the current study is to obtain morphometric and morphological data on the deep femoral artery and its branches and to investigate their clinical importance in the Turkish population. Morphometric measurements of the deep femoral artery and femoral artery were performed. The diameters of the femoral artery and deep femoral artery were measured in the axial plane. Classification was made according to the size of these diameters. A morphological classification was obtained by examining the variations of the deep femoral artery branches. The distance from the origin of the deep femoral artery to the midpoint of the inguinal ligament was 39.56 ± 8.52 mm, and the distances from the origin of the lateral circumflex femoral artery to the medial circumflex femoral artery were 17.15 ± 4.79 mm and 12.52 ± 4.58 mm, respectively. The study results show that there was a significant difference between genders in terms of the diameters measured. In the classification made by using the diameters, Type D (39%) had the highest rate, whereas Type C had the lowest rate (7.3%). According to the morphological classification, Type I (52.1%) was the most common in all individuals, and Type V and Type VII (2.3%) were the least common. Our study includes both morphometric and morphological information about the femoral artery and deep femoral artery of the Turkish population. We consider that the current study will be useful for cardiologists, interventional radiologists, orthopedists, and regional surgeons in clinical practice.","PeriodicalId":11978,"journal":{"name":"European journal of anatomy","volume":"98 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80556162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel E Jen, Maimuna A Adam, S. Garba, M. Attah, N. Dibal
Ground leaves of Lawsonia inermis (LI) made into a paste has been used from the Bronze Age as cosmetic application. Para-Phenylenediamine (PPD) is an organic compound that is added to LI to increase its aesthetic appearance and longevity. Addition of PPD increases the possibility of allergic contact dermatitis from LI tattoo combinations, and may be absorbed through the skin, affecting body organs. The current study was conducted to determine the effect of this mixture on the histology of skin, liver and kidney tissue. Thirty albino rats were grouped into five groups. The treatment protocol included a control group (I), application of LI paste alone for a period of two weeks (II), and four weeks (III), and a combination of LI and PPD for two weeks (IV), and four weeks (V). All rats in each group had an area on the lumbar region shaved and marked, and the paste was applied to this region. The rats were sacrificed after the experimental period and the tissues of interest removed for further histological and morphometric analysis. Application of LI alone caused no observable histological changes, however, in combination with PPD, LI caused thinning of the epidermis, reduction in the quantity of collagen fibers in the dermis, distorted the arrangement of hepatocytes, caused infiltration of inflammatory cells into the liver tissue and distortion in the arrangement of renal tubular epithelial cells. The longer the exposure to LI and PPD, the more alteration to the normal histology of tissues.
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