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Background parenchymal enhancement in CEM and MRI: Is there always a high agreement? 背景：CEM和MRI的实质增强：是否总是高度一致？
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111903
Francesca Ferrara , Ambra Santonocito , William Vogel , Charlotte Trombadori , Calogero Zarcaro , Michael Weber , Panagiotis Kapetas , Thomas H. Helbich , Pascal A.T. Baltzer , Paola Clauser

Introduction

Background parenchymal enhancement (BPE) refers to the physiological enhancement of breast fibroglandular tissue. This study aimed to determine the agreement of BPE evaluation between contrast enhanced mammography (CEM) and magnetic resonance imaging (MRI) and investigate potential confounders.

Materials and methods

This retrospective, IRB-approved study included women recalled from screening or with inconclusive findings on mammography and/or ultrasound, who underwent both CEM and MRI between 2018 and 2022. Imaging protocols followed international recommendations. Two breast radiology fellows assessed density and BPE on CEM and MRI using BI-RADS, evaluating the early post-contrast acquisition (EP). In addition, BPE on MRI was assessed in the late post-contrast acquisition (LP). Data on menopausal status, breast thickness, and compression force were retrieved. Univariate and multivariate analyses were used.

Results

343 patients were consecutively enrolled. Post-menopausal patients showed lower BPE levels (p < 0.001). Agreement on BPE levels between CEM and MRI in the EP was fair (R1 κ = 0.342, R2 κ = 0.383). In the LP agreement was moderate for R1 (κ = 0.432) and fair for R2 (κ 0.368). There was a significant correlation between BPE and density in CEM (R1 ρ 0.399, R2 ρ 0.441; p < 0.001). A negative correlation was found on CEM between BPE and compression force (ρ −0.100, p = 0.001). Inter-reader agreement was high with both modalities (CEM κ = 0.678, MRI-EP κ = 0.690, MRI-EP κ = 0.692).

Conclusions

The agreement of BPE assessment between MRI and CEM was fair to moderate and reproducibility among readers was high. Compression force and mammographic breast density seem to influence BPE levels in CEM.
简介：背景实质增强是指乳腺纤维腺组织的生理增强。本研究旨在确定对比增强乳房x线摄影（CEM）和磁共振成像（MRI）之间BPE评估的一致性，并调查潜在的混杂因素。材料和方法：这项经irb批准的回顾性研究纳入了2018年至2022年期间接受CEM和MRI检查的从筛查中召回或乳房x光检查和/或超声检查结果不确定的女性。成像方案遵循国际建议。两名乳腺放射学研究员使用BI-RADS评估CEM和MRI上的密度和BPE，评估早期对比后获取（EP）。此外，在造影后获取（LP）后期，对MRI上的BPE进行评估。检索绝经状态、乳房厚度和压缩力的数据。采用单因素和多因素分析。结果：343例患者连续入组。结论：MRI和CEM对BPE评估的一致性为中等至中等，读者的重复性高。压缩力和乳房x线摄影密度似乎影响CEM的BPE水平。
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引用次数: 0
Navigating the ethical and regulatory landscape of AI integration in radiology 引导人工智能在放射学中的整合的伦理和监管格局。
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111910
Yanxia Jia , Liang Han , Yilong Dai , Chengqiang Jin
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引用次数: 0
Peritherapeutic intra-arterial flow changes predict long-term stent patency in patients with severe intracranial artery stenosis receiving PTAS 在接受PTAS治疗的严重颅内动脉狭窄患者中，围治疗期动脉内血流变化可预测支架的长期通畅。
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111913
Feng-Chi Chang , Chia-Jen Wu , Kan Ling , Ting-Yi Chen , Jiing-Feng Lirng , Chia-Hung Wu

Background and purpose

The quantitative intra-arterial flow dynamics following percutaneous transluminal angioplasty and stenting (PTAS) for severe intracranial artery stenosis have never been investigated. We aimed to evaluate peritherapeutic intracranial artery flow dynamics following PTAS with quantitative magnetic resonance angiography (qMRA) to predict long-term stent patency.

Design

This is a prospective, single-center study.

Methods

We recruited participants with severe symptomatic stenosis from intracranial internal carotid artery (ICA) to M1 segment of middle cerebral artery (MCA) between 2018 and 2022. qMRA was performed before (preprocedural), within 24 h after (early postprocedural) and 12 months after (delayed postprocedural) PTAS, and parameters including bilateral M1 segments and basilar artery (BA) flow were recorded. The calibrated M1 ratio was calculated using contralateral M1 (cM1) and BA (cMB) flows as references. We assessed differences in qMRA parameters between subjects with and without significant 12-month in-stent restenosis (ISR).

Results

Forty-four subjects (12 with + 32 without ISR ≥ 50 %) were included. The early postprocedural M1 flow was higher than preprocedural M1 flow in subjects with (p = 0.030) and without (p = 0.031) ISR. The early postprocedural healthy-side M1 flow was lower than preprocedural healthy-side M1 flow (p = 0.014) in subjects without ISR. Both the early (p < 0.001) and delayed (p = 0.014) cM1s were greater than the preprocedural cM1. The residual stenosis grade was positively correlated with delayed postprocedural cM1 in all subjects (r2 = 0.190; p = 0.003).

Conclusions

The cM1 and a distinct flow dynamic pattern on early qMRA (within 24 h after PTAS) may predict 12-month ISR.
背景与目的：经皮腔内血管成形术和支架植入术（PTAS）治疗严重颅内动脉狭窄后的定量动脉内血流动力学从未被研究过。我们的目的是通过定量磁共振血管造影（qMRA）评估PTAS后围治疗期颅内动脉血流动力学，以预测长期支架通畅。设计：这是一项前瞻性单中心研究。方法：我们招募了2018年至2022年期间颅内颈内动脉（ICA）至大脑中动脉（MCA） M1段严重症状性狭窄的参与者。术前、术后早期、术后12个月分别行qMRA，记录双侧M1段及基底动脉（BA）血流参数。校正后的M1比率以对侧M1 （cM1）和BA （cMB）流为参考计算。我们评估了有12个月支架内再狭窄（ISR）和没有明显再狭窄（ISR）受试者之间qMRA参数的差异。结果：纳入44例受试者（12例+ 32例，无ISR≥50%）。有ISR （p = 0.030）和无ISR （p = 0.031）的受试者术后早期M1流高于术前M1流。无ISR的患者术后早期健康侧M1血流明显低于术前（p = 0.014）。早期(p 2 = 0.190；p = 0.003)。结论：早期qMRA （PTAS后24小时内）的cM1和明显的血流动力学模式可以预测12个月的ISR。
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引用次数: 0
Coronary artery calcification severity in long term breast cancer survivors treated with isolated contemporary radiotherapy: Relation to dose and CV risk factors 接受孤立当代放射治疗的长期乳腺癌幸存者冠状动脉钙化严重程度：与剂量和CV危险因素的关系
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111909
Pauline Krug , Xavier Geets , Martine Berlière , François Duhoux , Christophe Beauloye , Agnès Pasquet , David Vancraeynest , Anne-Catherine Pouleur , Bernhard L. Gerber , FESC FACC FAHA

Background

Ancillary breast cancer (BC) radiation therapy (RT), particularly associated with chemotherapy, increases the risk of coronary artery disease (CAD). However, it remains unclear whether this risk also applies to isolated contemporary radiotherapy without chemotherapy.

Methods

Seventy-five BC patients (35 left-sided and 40 right-sided) treated with RT and available dosimetry, prospectively underwent Agatston calcium score (CAC) and coronary CT angiography (CTCA) a median of 11 ± 1 years later and were compared to 75 age- and cardiovascular (CV) risk factor-matched female controls without a history of cancer.

Results

BC patients and controls had similar ages (62 ± 7 vs. 61 ± 7 years, p = 0.63), CV risk factors and estimated Score2/OP risk (3.8 % IQR 2.6–6 vs. 3.3 % IQR 2.3–5.4, p = 0.52). CAC scores (0 IQR 0–79 vs. 0 IQR 0–34, p = 0.62) and age-predicted percentile CAC scores (p = 0.61) were similar between BC patients and controls, with no significant difference between left- and right-sided RT. Multivariable analysis revealed that CAC scores in BC patients were predicted only by a family history of CAD and by Score-2/OP risk, but not by cardiac radiation exposure. By CTCA 68 % of BC patients had no or very mild coronary disease, and only 14 % had more than moderate stenosis (>50 %), which was predicted by CAC scores > 79 (AUC = 0.97).

Conclusion

Eleven years post-treatment with isolated contemporary RT for BC, patients exhibited similar CAC severity as age- and risk factor-matched controls. CAC was associated only with CV risk factors, but not radiation dose, suggesting contemporary RT for BC is not linked to higher subclinical CAD prevalence.
背景：辅助乳腺癌（BC）放射治疗（RT），特别是与化疗相关，增加冠状动脉疾病（CAD）的风险。然而，尚不清楚这种风险是否也适用于不加化疗的孤立当代放疗。方法：75例BC患者（35例左侧和40例右侧）接受RT和可用剂量法治疗，在中位11±1年后进行Agatston钙评分（CAC）和冠状动脉CT血管造影（CTCA），并与75例年龄和心血管（CV）危险因素匹配的无癌症史的女性对照进行比较。结果：BC患者和对照组具有相似的年龄（62±7岁vs 61±7岁，p = 0.63）、CV危险因素和Score2/OP估计风险（3.8% IQR 2.6-6 vs 3.3% IQR 2.3-5.4, p = 0.52）。CAC评分（0 IQR 0-79 vs 0 IQR 0-34, p = 0.62）和年龄预测百分位数CAC评分（p = 0.61）在BC患者和对照组之间相似，左右侧rt之间无显著差异。多变量分析显示，BC患者的CAC评分仅由CAD家族史和Score-2/OP风险预测，而与心脏辐射暴露无关。到CTCA时，68%的BC患者没有或非常轻微的冠状动脉疾病，只有14%的患者有中度以上的狭窄（bbb50 %），这是由CAC评分bbb79 （AUC = 0.97）预测的。结论：接受孤立的BC当代RT治疗11年后，患者的CAC严重程度与年龄和危险因素匹配的对照组相似。CAC仅与心血管危险因素相关，而与辐射剂量无关，这表明当代BC放疗与亚临床CAD患病率升高无关。
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引用次数: 0
Increasing joy of reading and the impact of scientific articles– the benefits of RadioComics 增加阅读的乐趣和科学文章的影响-无线电漫画的好处。
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111862
Isabel Molwitz , Ingrid Boehm
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引用次数: 0
Contrast-enhanced pseudo-CT of finger joints: Improved diagnostic confidence for detection of inflammatory erosions 手指关节增强伪ct：提高炎性糜烂检测的诊断信心。
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111856
Christoph Stern , Georg C. Feuerriegel , Christoph Germann , Stefan Sommer , Daniel Nanz , Reto Sutter

Purpose

To evaluate the interest of additional pseudo-CT images to standard clinical contrast-enhanced MR images (CE-MRI) in the detection of inflammatory erosions and to differentiate them from intraosseous ganglia at the finger joints.

Method

47 prospectively included patients with suspected or diagnosed rheumatoid arthritis received a CE-MRI of the fingers. Additionally, pseudo-CT images were derived from non-contrast MRI (pCT) and from contrast-enhanced MRI data (CE-pCT) using a high-resolution gradient-echo 3D fast low-angle shot sequence (FLASH), respectively. CE-MRI, pCT, and CE-pCT images were evaluated for erosions and intraosseous ganglia at the metacarpophalangeal and proximal interphalangeal joints by two musculoskeletal radiologists. Findings were defined on CE-MRI by an experienced independent 3rd reader which served as reference standard. Diagnostic confidence (1 = worst, 4 = best) was rated for 3 different image sets (1 = CE-MRI, 2 = CE-MRI + pCT, 3 = CE-MRI + CE-pCT) and compared.

Results

Reference standard revealed 44 erosions and 37 intraosseous ganglia on CE-MRI. Diagnostic confidence for CE-MRI was moderate for erosions (both readers) and intraosseous ganglia (reader 2). For the combination of CE-MRI and pCT, high confidence levels were observed for erosions for both readers (median 3 (Q1–Q3: 2.5–3) and 3 (3–3); p<.001 and p<.001) and for intraosseous ganglia for reader 2 (3 (3–3); p<.001). CE-MRI combined with CE-pCT showed very high confidence levels for both readers for erosions (4 (3–4) and 4 (4–4); p<.001 and p<.001) and for intraosseous ganglia (4 (4–4) and 4 (4–4); p<.001 and p<.001).

Conclusions

Pseudo-CT combined with CE-MRI increases the confidence in detection of inflammatory erosions at the finger joints, with CE-pCT being superior to pCT.
目的：评价在标准临床增强磁共振成像（CE-MRI）基础上附加伪ct图像对炎性糜烂的检测价值，并将其与手指关节骨内神经节区分开来。方法：前瞻性纳入47例疑似或诊断为类风湿关节炎的患者，接受手指CE-MRI检查。此外，伪ct图像分别来自使用高分辨率梯度回波3D快速低角度拍摄序列（FLASH）的非对比MRI （pCT）和对比增强MRI数据（CE-pCT）。由两名肌肉骨骼放射科医生评估掌指关节和近端指间关节的糜烂和骨内神经节的CE-MRI、pCT和CE-pCT图像。结果由经验丰富的独立第三阅读者作为参考标准在CE-MRI上定义。对3个不同图像集（1 = CE-MRI, 2 = CE-MRI + pCT, 3 = CE-MRI + CE-pCT）的诊断置信度（1 =最差，4 =最好）进行评分并进行比较。结果：参考标准CE-MRI显示糜烂44处，骨内神经节37处。CE-MRI对糜烂（两个读卡器）和骨内神经节（读卡器2）的诊断置信度中等。对于CE-MRI和pCT的结合，两个读卡器对糜烂的诊断置信度都很高(中位数为3 （Q1-Q3: 2.5-3）和3 (3-3)；结论：伪ct联合CE-MRI可提高手指关节炎性糜烂的检测置信度，CE-pCT优于pCT。
{"title":"Contrast-enhanced pseudo-CT of finger joints: Improved diagnostic confidence for detection of inflammatory erosions","authors":"Christoph Stern ,&nbsp;Georg C. Feuerriegel ,&nbsp;Christoph Germann ,&nbsp;Stefan Sommer ,&nbsp;Daniel Nanz ,&nbsp;Reto Sutter","doi":"10.1016/j.ejrad.2024.111856","DOIUrl":"10.1016/j.ejrad.2024.111856","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the interest of additional pseudo-CT images to standard clinical contrast-enhanced MR images (CE-MRI) in the detection of inflammatory erosions and to differentiate them from intraosseous ganglia at the finger joints.</div></div><div><h3>Method</h3><div>47 prospectively included patients with suspected or diagnosed rheumatoid arthritis received a CE-MRI of the fingers. Additionally, pseudo-CT images were derived from non-contrast MRI (pCT) and from contrast-enhanced MRI data (CE-pCT) using a high-resolution gradient-echo 3D fast low-angle shot sequence (FLASH), respectively. CE-MRI, pCT, and CE-pCT images were evaluated for erosions and intraosseous ganglia at the metacarpophalangeal and proximal interphalangeal joints by two musculoskeletal radiologists. Findings were defined on CE-MRI by an experienced independent 3rd reader which served as reference standard. Diagnostic confidence (1 = worst, 4 = best) was rated for 3 different image sets (1 = CE-MRI, 2 = CE-MRI + pCT, 3 = CE-MRI + CE-pCT) and compared.</div></div><div><h3>Results</h3><div>Reference standard revealed 44 erosions and 37 intraosseous ganglia on CE-MRI. Diagnostic confidence for CE-MRI was moderate for erosions (both readers) and intraosseous ganglia (reader 2). For the combination of CE-MRI and pCT, high confidence levels were observed for erosions for both readers (median 3 (Q1–Q3: 2.5–3) and 3 (3–3); <em>p&lt;</em>.001 and <em>p&lt;</em>.001) and for intraosseous ganglia for reader 2 (3 (3–3); <em>p&lt;</em>.001). CE-MRI combined with CE-pCT showed very high confidence levels for both readers for erosions (4 (3–4) and 4 (4–4); <em>p&lt;</em>.001 and <em>p&lt;</em>.001) and for intraosseous ganglia (4 (4–4) and 4 (4–4); <em>p&lt;</em>.001 and <em>p&lt;</em>.001).</div></div><div><h3>Conclusions</h3><div>Pseudo-CT combined with CE-MRI increases the confidence in detection of inflammatory erosions at the finger joints, with CE-pCT being superior to pCT.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111856"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT perfusion and MRI: A combined approach for hepatocellular carcinoma diagnosis and follow-up after locoregional treatment
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2025.111928
Georgios Kalarakis , Evangelia G. Chryssou , Kostas Perisinakis , Michail E. Klontzas , Dimitrios Samonakis , Adam Hatzidakis

Objective

CT liver perfusion (CTLP) has been well validated for hepatocellular carcinoma (HCC) detection, characterization, and treatment response evaluation. However, its role in HCC management algorithms remains unclear. This study aims to assess the diagnostic performance of CTLP alone or as an adjunct to MRI in patients considered for- or undergoing locoregional treatment for HCC.

Material and Methods

Thirty-nine patients under HCC surveillance (36 male, 31 cirrhotic, 16 pretreatment, 19 post-transarterial chemoembolization, 2 post-ablation) underwent MRI and CTLP in a single center within a 45-day interval. Two readers identified and characterized all observations on MRI using Liver Imaging Reporting and Data System (LI-RADS) v2018 criteria. CTLP assessment was based on Mean Slope of Increase (MSI), Time To Peak (TTP), Hepatic arterial Blood Flow (HaBF) and Hepatic Arterial Fraction (HAF) maps and established cut-offs. Diagnostic performance of MRI, CTLP, and their combination was evaluated for treated and untreated lesions using imaging or pathology as reference standard.

Results

Of the total 33 treated and 61 untreated lesions, 13 and 41 were considered viable HCCs. CTLP demonstrated 75.9 % sensitivity and 95 % specificity compared to 72.2 % and 100 % for MRI (p > 0.05). Combining both modalities increased sensitivity to 85.2 % (p < 0.05) and maintained specificity at 97.5 % (p > 0.05). The combined approach led to an LR category change in 5 treated and 19 untreated lesions and affected management in 5 cases.

Conclusion

CTLP and MRI have comparable diagnostic performance for HCC. A combined approach improves sensitivity, without sacrificing specificity. This approach might enable more efficient patient selection for early and individualized loco-regional treatment.
{"title":"CT perfusion and MRI: A combined approach for hepatocellular carcinoma diagnosis and follow-up after locoregional treatment","authors":"Georgios Kalarakis ,&nbsp;Evangelia G. Chryssou ,&nbsp;Kostas Perisinakis ,&nbsp;Michail E. Klontzas ,&nbsp;Dimitrios Samonakis ,&nbsp;Adam Hatzidakis","doi":"10.1016/j.ejrad.2025.111928","DOIUrl":"10.1016/j.ejrad.2025.111928","url":null,"abstract":"<div><h3>Objective</h3><div>CT liver perfusion (CTLP) has been well validated for hepatocellular carcinoma (HCC) detection, characterization, and treatment response evaluation. However, its role in HCC management algorithms remains unclear. This study aims to assess the diagnostic performance of CTLP alone or as an adjunct to MRI in patients considered for- or undergoing locoregional treatment for HCC.</div></div><div><h3>Material and Methods</h3><div>Thirty-nine patients under HCC surveillance (36 male, 31 cirrhotic, 16 pretreatment, 19 post-transarterial chemoembolization, 2 post-ablation) underwent MRI and CTLP in a single center within a 45-day interval. Two readers identified and characterized all observations on MRI using Liver Imaging Reporting and Data System (LI-RADS) v2018 criteria. CTLP assessment was based on Mean Slope of Increase (MSI), Time To Peak (TTP), Hepatic arterial Blood Flow (HaBF) and Hepatic Arterial Fraction (HAF) maps and established cut-offs. Diagnostic performance of MRI, CTLP, and their combination was evaluated for treated and untreated lesions using imaging or pathology as reference standard.</div></div><div><h3>Results</h3><div>Of the total 33 treated and 61 untreated lesions, 13 and 41 were considered viable HCCs. CTLP demonstrated 75.9 % sensitivity and 95 % specificity compared to 72.2 % and 100 % for MRI (p &gt; 0.05). Combining both modalities increased sensitivity to 85.2 % (p &lt; 0.05) and maintained specificity at 97.5 % (p &gt; 0.05). The combined approach led to an LR category change in 5 treated and 19 untreated lesions and affected management in 5 cases.</div></div><div><h3>Conclusion</h3><div>CTLP and MRI have comparable diagnostic performance for HCC. A combined approach improves sensitivity, without sacrificing specificity. This approach might enable more efficient patient selection for early and individualized loco-regional treatment.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111928"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiological evaluation of pelvic venous Disorders: A comprehensive review
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2025.111940
Weili Yang , Linglin Sun , YanQiao Shi , Tao Ye , Qiang Li
Pelvic venous disorder (PVD) is a common gynecological disorder caused by chronic pelvic venous congestion. Clinically, it primarily manifests as lower abdominal pain, lower back pain, dyspareunia, increased menstrual flow, and increased vaginal discharge, though positive physical signs are few. The gynecological examination may reveal bilateral ovarian tenderness. The clinical symptoms of PVD are nonspecific and overlap with those of other gynecological conditions, leading to a high rate of missed diagnoses and making accurate diagnoses challenging. The exact etiology of PVD is not fully understood, and there is currently no comprehensive diagnostic standard. Radiology plays a crucial role in the diagnosis and treatment of PVD. Through invasive or non-invasive imaging techniques, pelvic lesions can be assessed, providing precise guidance for clinical treatment and evaluation of therapeutic efficacy. This review introduces the causes of PVD, the advantages and disadvantages of various non-invasive and invasive imaging examinations, and the key diagnostic points. The aim of this review is to help clinicians and radiologists better understand the disease and improve the accuracy of imaging diagnosis.
{"title":"Radiological evaluation of pelvic venous Disorders: A comprehensive review","authors":"Weili Yang ,&nbsp;Linglin Sun ,&nbsp;YanQiao Shi ,&nbsp;Tao Ye ,&nbsp;Qiang Li","doi":"10.1016/j.ejrad.2025.111940","DOIUrl":"10.1016/j.ejrad.2025.111940","url":null,"abstract":"<div><div>Pelvic venous disorder (PVD) is a common gynecological disorder caused by chronic pelvic venous congestion. Clinically, it primarily manifests as lower abdominal pain, lower back pain, dyspareunia, increased menstrual flow, and increased vaginal discharge, though positive physical signs are few. The gynecological examination may reveal bilateral ovarian tenderness. The clinical symptoms of PVD are nonspecific and overlap with those of other gynecological conditions, leading to a high rate of missed diagnoses and making accurate diagnoses challenging. The exact etiology of PVD is not fully understood, and there is currently no comprehensive diagnostic standard. Radiology plays a crucial role in the diagnosis and treatment of PVD. Through invasive or non-invasive imaging techniques, pelvic lesions can be assessed, providing precise guidance for clinical treatment and evaluation of therapeutic efficacy. This review introduces the causes of PVD, the advantages and disadvantages of various non-invasive and invasive imaging examinations, and the key diagnostic points. The aim of this review is to help clinicians and radiologists better understand the disease and improve the accuracy of imaging diagnosis.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111940"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MRI and ADC histogram features as predictors of distant metastasis and prognosis in alveolar soft tissue sarcomas
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2024.111907
Fan Meng , Junhui Yuan , Shaobo Fang , Yue Wu , Dongqiu Shan , Nannan Shao , Xuejun Chen

Objective

To evaluate the value of pre-treatment MRI features and whole-volume apparent diffusion coefficient (ADC) histogram parameters in predicting distant metastasis and prognosis in alveolar soft part sarcoma (ASPS).

Methods

A retrospective analysis was performed on 43 patients with histologically confirmed ASPS, including 25 with metastasis and 18 without at the time of diagnosis. All patients underwent routine MRI, including diffusion-weighted imaging (DWI) and enhanced T1-weighted imaging. Clinical data and MRI features of the primary tumor were recorded. MATLAB software was used to analyze ADC histogram parameters. Differences in clinical data and MRI features between the metastasis and non-metastasis groups were assessed using t-tests or chi-square tests. Histogram parameters were compared using independent t-tests or Mann-Whitney U tests. Multivariate binary logistic regression analysis was used to identify independent factors associated with metastasis and to establish a combined model. Receiver operating characteristic (ROC) analysis evaluated the diagnostic performance of independent factors and the combined model. Kaplan-Meier analysis and Cox proportional hazards models assessed the risk of distant metastasis and overall survival (OS).

Results

Significant differences were found between the metastasis and non-metastasis groups in tumor size, heterogeneous signal intensity on T2WI, peritumoral edema, and peritumoral enhancement (P = 0.014, 0.001, 0.019, and < 0.001, respectively). The metastasis group had lower ADCmean and ADC50th values (P = 0.001, 0.046, respectively). Logistic regression identified tumor size, peritumoral enhancement, and ADCmean as independent predictors of metastasis. The combined model showed the highest AUC (0.872, 95 % CI: 0.735–0.954). Size and ADCmean were independent factors for OS.

Conclusion

MRI features and ADC histogram parameters can effectively predict distant metastasis and prognosis in ASPS.
{"title":"MRI and ADC histogram features as predictors of distant metastasis and prognosis in alveolar soft tissue sarcomas","authors":"Fan Meng ,&nbsp;Junhui Yuan ,&nbsp;Shaobo Fang ,&nbsp;Yue Wu ,&nbsp;Dongqiu Shan ,&nbsp;Nannan Shao ,&nbsp;Xuejun Chen","doi":"10.1016/j.ejrad.2024.111907","DOIUrl":"10.1016/j.ejrad.2024.111907","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the value of pre-treatment MRI features and whole-volume apparent diffusion coefficient (ADC) histogram parameters in predicting distant metastasis and prognosis in alveolar soft part sarcoma (ASPS).</div></div><div><h3>Methods</h3><div>A retrospective analysis was performed on 43 patients with histologically confirmed ASPS, including 25 with metastasis and 18 without at the time of diagnosis. All patients underwent routine MRI, including diffusion-weighted imaging (DWI) and enhanced T1-weighted imaging. Clinical data and MRI features of the primary tumor were recorded. MATLAB software was used to analyze ADC histogram parameters. Differences in clinical data and MRI features between the metastasis and non-metastasis groups were assessed using t-tests or chi-square tests. Histogram parameters were compared using independent t-tests or Mann-Whitney U tests. Multivariate binary logistic regression analysis was used to identify independent factors associated with metastasis and to establish a combined model. Receiver operating characteristic (ROC) analysis evaluated the diagnostic performance of independent factors and the combined model. Kaplan-Meier analysis and Cox proportional hazards models assessed the risk of distant metastasis and overall survival (OS).</div></div><div><h3>Results</h3><div>Significant differences were found between the metastasis and non-metastasis groups in tumor size, heterogeneous signal intensity on T2WI, peritumoral edema, and peritumoral enhancement (<em>P</em> = 0.014, 0.001, 0.019, and &lt; 0.001, respectively). The metastasis group had lower ADCmean and ADC50th values (<em>P</em> = 0.001, 0.046, respectively). Logistic regression identified tumor size, peritumoral enhancement, and ADCmean as independent predictors of metastasis. The combined model showed the highest AUC (0.872, 95 % CI: 0.735–0.954). Size and ADCmean were independent factors for OS.</div></div><div><h3>Conclusion</h3><div>MRI features and ADC histogram parameters can effectively predict distant metastasis and prognosis in ASPS.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"183 ","pages":"Article 111907"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143159516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiothoracic manifestations of storage diseases in adults: A pictorial review
IF 3.2 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Journal of Radiology
Pub Date : 2025-02-01 DOI: 10.1016/j.ejrad.2025.111955
Rebecca Darracott , Robert M. Cooper , Raad Mohiaddin , Tomas Franquet , Monika Radike
Storage diseases are a diverse group of conditions marked by abnormal accumulations of substances like glycogen, fatty acids, and proteins in various tissues, including the heart and lungs. These rare diseases can pose significant diagnostic challenges due to their broad range of clinical presentations and involvement of multiple organs. Identification of key imaging findings can aid in early diagnosis and guide management. In this review, we present the cardiothoracic manifestations of these storage diseases, using imaging examples to highlight their clinical relevance.
{"title":"Cardiothoracic manifestations of storage diseases in adults: A pictorial review","authors":"Rebecca Darracott ,&nbsp;Robert M. Cooper ,&nbsp;Raad Mohiaddin ,&nbsp;Tomas Franquet ,&nbsp;Monika Radike","doi":"10.1016/j.ejrad.2025.111955","DOIUrl":"10.1016/j.ejrad.2025.111955","url":null,"abstract":"<div><div>Storage diseases are a diverse group of conditions marked by abnormal accumulations of substances like glycogen, fatty acids, and proteins in various tissues, including the heart and lungs. These rare diseases can pose significant diagnostic challenges due to their broad range of clinical presentations and involvement of multiple organs. Identification of key imaging findings can aid in early diagnosis and guide management. In this review, we present the cardiothoracic manifestations of these storage diseases, using imaging examples to highlight their clinical relevance.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"184 ","pages":"Article 111955"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143337584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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