European Journal of Radiology最新文献

{"title":"Establishing updated diagnostic reference levels for interventional radiology: a national Italian survey incorporating procedure complexity indices – Part II: interventional neuroradiology","authors":"Monica Cavallari ,&nbsp;Loredana D’Ercole ,&nbsp;Sveva Grande ,&nbsp;Catherine Klersy ,&nbsp;Renato Padovani ,&nbsp;Antonio Orlacchio ,&nbsp;Gaetano Compagnone ,&nbsp;Antonella Rosi ,&nbsp;Alessandra Palma","doi":"10.1016/j.ejrad.2026.112662","DOIUrl":"10.1016/j.ejrad.2026.112662","url":null,"abstract":"<div><h3>Introduction</h3><div>To update the Italian Diagnostic Reference Levels (NDRLs) in interventional neuroradiology, the Istituto Superiore di Sanità coordinated a working group with consolidated expertise in this field. Establishing DRLs in interventional procedures is particularly challenging due to the complexity influenced by clinical and technical factors. For this reason, aim of this work is to provide DRLs that also take into account procedure complexity.</div></div><div><h3>Material and methods</h3><div>Data were collected from 20 Italian hospitals concerning cerebral angiography(CA), embolization of cerebral aneurysms (ECA), and Mechanical Thrombectomy (MT). For each procedure, Air-Kerma (K_a,r), Kerma-Area-Product(P_KA), and Fluoroscopy Time(FT) were recorded.</div><div>Data related to patient age, sex, and radiological equipment were registered. Additionally, for CA number of arteries evaluated, diagnostic priority (elective or emergency), and study type were documented. For ECA, aneurysm status, dome-to-neck ratio, aneurysm size, aneurysm location, and aneurysm morphology were recorded. For MT, collected data included occlusion type, thrombus location, and use of a stent retriever.</div></div><div><h3>Results</h3><div>P_KA distributions were analysed with non-parametric tests and generalized linear regression models to identify clinical and technical factors affecting dosimetry. Log transformations helped develop a complexity score to classify procedures. The new NDRLs are 191 Gy.cm² for CA (71 Gy.cm² for simple, 117 Gy.cm² for medium, 198 Gy.cm² for complex), 252 Gy.cm² for ECA (136 Gy.cm² for simple, 174 Gy.cm² medium, 268 Gy.cm² complex) and 169 Gy.cm² for MT (71 Gy.cm² for simple, 132 Gy.cm² for medium, 169 Gy.cm² for complex).</div></div><div><h3>Conclusion</h3><div>This study establishes updated national diagnostic reference levels for interventional neuroradiology in Italy through a comprehensive complexity-stratified approach. The research demonstrates the critical importance of regular DRL updates to reflect evolving practice patterns and technological advances, offering a more nuanced framework that recognizes the inherent variability of neuro interventional procedures across different complexity tiers.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112662"},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146009466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of photon counting CT for the assessment of native heart valves","authors":"Charles Mayard ,&nbsp;Salim Si-Mohamed ,&nbsp;Angèle Houmeau ,&nbsp;Cyril Prieur ,&nbsp;Jean-Nicolas Dacher ,&nbsp;Loic Boussel ,&nbsp;Philippe Douek ,&nbsp;Sara Boccalini","doi":"10.1016/j.ejrad.2026.112661","DOIUrl":"10.1016/j.ejrad.2026.112661","url":null,"abstract":"<div><h3>Objectives</h3><div>Systematic data about whether photon counting detector CT (PCD-CT) could improve the assessment of native heart valves is lacking. Thus, the aim of this study was to assess the performances of PCD-CT for the evaluation of native heart valves as compared to energy integrating detector CT (EID-CT).</div></div><div><h3>Methods</h3><div>Patients necessitating coronary artery CT were prospectively included (February 2021 to December 2022) to undergo an ECG-gated PCD-CT and EID-CT. A subjective assessment of the sharpness and conspicuity of each of the components of the four valves was performed with a 4-point scale. The number of small structures of the valvular apparati was calculated. The number of calcifications per leaflet and their localization within the thickness of the aortic leaflets were noted. The volume of the calcifications and the full width at mid weight (FWMH) of the aortic valve were calculated.</div></div><div><h3>Results</h3><div>Thirty-three patients (62 ± 13 years; 88 % men) were included. Conspicuity of aortic, mitral, and pulmonary valvular structures was increased with PCD-CT (all &lt; 0.05) except for the aortic right-non-coronary commissure and the pulmonary right-left commissure (p = 0.06 and p = 0.07). Sharpness was superior for all the borders and the commissures of the aortic and mitral valve (all p &lt; 0.05). More fine structures (nodules, chordae) and calcifications were visible with PCD-CT. The precise localization of the calcifications could be assessed with PCD-CT in most cases (70 %) while the volumes were similar (p = 0.07). FWMH was lower with PCD-CT (1.7(IQ = 1.1) vs 2.5 mm (IQ = 1.3); p &lt; 0.01).</div></div><div><h3>Conclusions</h3><div>PCD-CT yielded better subjective and objective image quality of native aortic, mitral and pulmonary valves and allowed for more structures to be detected compared to EID-CT. This might result in earlier, improved diagnosis of valve pathologies.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112661"},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring white matter abnormalities in different subtypes of spastic cerebral palsy using fixel-based analysis","authors":"Chih-Chien Tsai ,&nbsp;Chia-Ling Chen ,&nbsp;Chih-Hua Yeh ,&nbsp;Yao-Liang Chen ,&nbsp;Yu-Chun Lin ,&nbsp;Jur-Shan Cheng ,&nbsp;Jiun-Jie Wang","doi":"10.1016/j.ejrad.2025.112636","DOIUrl":"10.1016/j.ejrad.2025.112636","url":null,"abstract":"<div><h3>Purpose</h3><div>To examine the white matter integrity in participants with cerebral palsy (CP) and among its different subtypes through diffusion MRI.</div></div><div><h3>Methods</h3><div>34 participants with CP (19 boys, 15 girls; mean age: 13.9 ± 3.6 years) and 27 typically developing (TD) participants (14 boys, 13 girls; mean age: 14.5 ± 3.2 years) were enrolled. Diffusion-weighted and T2-weighted images were obtained. Clinical assessments included Gross Motor Function Classification System, Manual Ability Classification System, and Bimanual Fine Motor Function test. Diffusion-weighted images were analyzed by fixel-based analysis and Tract-based spatial statistics. Lesion map was calculated from the T2-weighted images.</div><div>Differences in fixel-based metrics between CP or its subtype to TD participants, and among different subtypes, were evaluated through connectivity-based fixel enhancement and non-parametric permutation testing. The association of fixel-based metrics with clinical assessment scores was examined through general linear model.</div></div><div><h3>Results</h3><div>White matter damage can be noticed in CP participants, including corpus callosum, corticospinal tract, thalamic radiation, and optic radiation, when compared to TD participants. Fixel-based analysis detected additional regions in genu of corpus callosum. Fixel-based metrics in thalamic radiation and corticospinal tract were related to the severity of the motor impairment. Participants with diplegia had damage in the body of the corpus callosum and optic radiation when compared to those with hemiplegia.</div></div><div><h3>Conclusion</h3><div>Fixel-based<!--> <!-->analysis is sensitive to identify subtle white matter alterations that vary by CP<!--> <!-->subtype. The microstructural and macrostructural integrity of the corticospinal<!--> <!-->tract and thalamic<!--> <!-->radiation could be considered as promising image-based biomarkers to enhance clinical assessment.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112636"},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive quantitative and qualitative assessment of TGSE-BLADE DWI in postoperative imaging following intracranial tumor resection","authors":"Christer Ruff ,&nbsp;Till-Karsten Hauser ,&nbsp;Paula Bombach ,&nbsp;Daniel Vogl ,&nbsp;Constantin Roder ,&nbsp;Frank Paulsen ,&nbsp;Deborah Staber ,&nbsp;Vivien Richter ,&nbsp;Leonie Zerweck ,&nbsp;Ulrike Ernemann ,&nbsp;Georg Gohla","doi":"10.1016/j.ejrad.2026.112659","DOIUrl":"10.1016/j.ejrad.2026.112659","url":null,"abstract":"<div><h3>Purpose</h3><div>Postoperative MRI plays a pivotal role in assessing residual disease and planning therapy after intracranial tumor resection. As acute perioperative infarction may mimic enhancing and non-enhancing tumor tissue in follow-up imaging, the initial postoperative MRI examination is essential for this purpose. However, conventional DWI techniques like RESOLVE are often impaired by artifacts from intracranial air. This study compares RESOLVE DWI with TGSE-BLADE DWI within early postoperative scans to improve diagnostic confidence in identifying ischemic changes.</div></div><div><h3>Method</h3><div>In a retrospective, institutional review board–approved study, 33 patients (mean age 52.3 ± 25.1 years) underwent a 1.5-Tesla MRI within 48 h of resection. RESOLVE and TGSE-BLADE DWI sequences were acquired in the same orientation and slice thickness of 5 mm. Two neuroradiologists blindly evaluated geometric distortion, susceptibility artifacts, overall image quality, and diagnostic confidence. Quantitative analysis included measuring signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values, image quality metrics and resection defect dimensions against T1-weighted images.</div></div><div><h3>Results</h3><div>TGSE-BLADE DWI exhibited significantly reduced geometric distortions and susceptibility artifacts near the resection site compared with RESOLVE DWI, producing superior qualitative image quality and diagnostic confidence (p &lt; 0.001). Conversely, RESOLVE DWI yielded slightly higher SNR and CNR. Measurements of the resection defect on TGSE-BLADE DWI closely matched those on T1-weighted images (p = 0.974), while RESOLVE DWI showed a significant discrepancy (p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>TGSE-BLADE DWI significantly minimizes artifacts and geometric distortions in intracranial postoperative imaging, thereby improving the detection of perioperative ischemic changes. This robust technique serves as an effective alternative to conventional EPI-based sequences in challenging settings with pronounced B₀ inhomogeneities, ultimately enhancing diagnostic confidence and patient care.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112659"},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal predictive value of MOLLI T1 mapping imaging for minimal clinically important difference after surgery for cervical spondylotic myelopathy","authors":"Ruo-Yu Wang ,&nbsp;Xiao-Dan Mu ,&nbsp;Yu-Jin Zhang ,&nbsp;Yi-Fei Peng ,&nbsp;Yue Liu ,&nbsp;Zi-Bo Wang ,&nbsp;Wei Yan ,&nbsp;Li Zhang","doi":"10.1016/j.ejrad.2026.112660","DOIUrl":"10.1016/j.ejrad.2026.112660","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the predictive value of MOLLI T₁ mapping imaging for the longitudinal changes in Minimal Clinical Important Difference (MCID) after surgery for patients with Cervical Spondylotic Myelopathy (CSM).</div></div><div><h3>Methods</h3><div>A prospective study enrolled 163 surgically treated CSM patients (October 2022–October 2023). All underwent preoperative conventional MRI and MOLLI T₁ mapping. The MCID was determined based on the difference in Modified Japanese Orthopedic Association (m JOA) scores before and at 3, 6, and 12 months after surgery. Patients with an MCID less than 2 were defined as the poor prognosis group, while those with an MCID of 2 or higher were defined as the good prognosis group. Patients were classified into the good prognosis and poor prognosis groups at 3, 6,12 months postoperatively. The differences in conventional MRI features and T₁ values between the two groups at these time points were compared. Univariate and multivariate logistic regression identified recovery predictors, with forest plots generated. Receiver operating characteristic (ROC) curve analysis assessed diagnostic performance.</div></div><div><h3>Results</h3><div>At 3 months, (27 good vs 136 poor). Only T₂WI hyperintensity differed between groups [Area under the receiver operating characteristic curve (AUC)=0.597, cut off = 0.1942; sensitivity = 40.74 %, specificity = 78.68 %]. At 6 months (60 good vs 103 poor), T₁ values showed significance (AUC = 0.690, cut off = 0.3091; sensitivity = 83.33 %, specificity = 47.57 %). At 12 months (100 good vs 63 poor), T₁ values demonstrated superior prediction (AUC = 0.875,cut off = 0.6389; sensitivity = 75.00 %, specificity = 88.89 %).</div></div><div><h3>Conclusion</h3><div>MOLLI T₁ mapping effectively predicts CSM recovery at 6,12 months postoperatively, with optimal diagnostic performance at 12 months.</div></div><div><h3>Critical relevance statement</h3><div>This study first employs MRI T₁ mapping to predict MCID outcomes in CSM patients, demonstrating its high predictive value for favorable postoperative prognosis and providing a reliable imaging parameter for outcome assessment.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112660"},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of diagnostic capability and subtypes classification for inguinal hernias between upright and supine ADCTs","authors":"Masahiko Nomura ,&nbsp;Takeshi Yoshikawa ,&nbsp;Takahiro Ueda ,&nbsp;Yoshiyuki Ozawa ,&nbsp;Hirona Kimata ,&nbsp;Yuya Ito ,&nbsp;Kenji Fujii ,&nbsp;Naruomi Akino ,&nbsp;Daisuke Takenaka ,&nbsp;Yoshiharu Ohno","doi":"10.1016/j.ejrad.2025.112647","DOIUrl":"10.1016/j.ejrad.2025.112647","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to directly compare diagnostic capability of inguinal herniation between upright area-detector CT (ADCT) and conventional supine ADCT under the Valsalva maneuver.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included 209 patients with 360 inguinal herniations and 123 patients without inguinal hernias. All patients underwent supine and upright ADCT for the evaluation of abdominal wall hernias within one week between May 2023 and March 2024. From this cohort, a total of 120 of 360 inguinal hernias and 120 of 304 non-inguinal hernias were computationally selected, and the probability of hernia was visually assessed by two board-certified general and abdominal radiologists with 5-point scales to assess subtypes of herniation. The final score for each hernia was determined as consensus of two investigators. To determine the capability of diagnosis for inguinal herniation in selected lesion groups, diagnostic performance was compared between upright and supine ADCTs using an ROC analysis. Then, sensitivity (SE), specificity (SP), and accuracy (AC) for differentiation of inguinal from non-inguinal hernias were compared between the two methods using McNemar’s test.</div></div><div><h3>Results</h3><div>The area under the curve (AUC) of upright ADCT (AUC = 0.96) was significantly larger than that of supine ADCT (AUC = 0.93, p &lt; 0.0001). Sensitivity (SE) and accuracy (AC) of upright ADCT (SE: 87.5 %, AC: 93.8 %) were significantly higher than those of supine ADCT (SE: 73.3 %, p &lt; 0.0001; AC: 86.7 %, p &lt; 0.0001).</div></div><div><h3>Conclusion</h3><div>Upright ADCT has better potential for the diagnosis and subtype classification of inguinal herniation than conventional supine ADCT when applied under the Valsalva maneuver.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112647"},"PeriodicalIF":3.3,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive MRI assessment of cerebrospinal fluid pressure in different phases of Ménière’s disease: a prospective study","authors":"Yongjia Chen ,&nbsp;Lu Jiang ,&nbsp;Zequn Nie ,&nbsp;Jing Liu ,&nbsp;Bo Pang ,&nbsp;Shuai Zhang ,&nbsp;Yijiang Bai ,&nbsp;Heng Liu ,&nbsp;Zihang Guo ,&nbsp;Jilin Nie ,&nbsp;Shuangyuan Zhou ,&nbsp;Lingyun Mei","doi":"10.1016/j.ejrad.2026.112658","DOIUrl":"10.1016/j.ejrad.2026.112658","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to determine whether there are differences of cerebrospinal fluid pressure (CSF-P) on patients with Ménière’s disease (MD) during different phases.</div></div><div><h3>Methods</h3><div>Noninvasive CSF-P measurement was performed using MRI with a fat-suppressed fast recovery fast spin echo T2-weighted sequence, with the optic nerve subarachnoid space width (ONSASW) posterior to the globe serving as an indicator. Endolymphatic hydrops (EH) grades and hearing thresholds were analysed to investigate the potential correlations with CSF-P.</div></div><div><h3>Results</h3><div>A total of 66 participants were included. At the location of 3 mm behind the globe, the ONSASW and CSF-P were significantly smaller in the acute phase of MD group compared to both the remission phase of MD group (<em>p</em> &lt; 0.001, <em>p</em> = 0.005, respectively) and control group (<em>p</em> &lt; 0.001, <em>p</em> = 0.043, respectively). No statistically significant differences were found between the remission phase of MD group and the control group (both <em>p</em> &gt; 0.05). Statistically significant correlation between CSF-P and hearing threshold was exclusively observed during the acute phase, with a correlation coefficient of 0.479 (<em>p</em> = 0.024). No significant associations between CSF-P and EH grades in both the two MD groups (all <em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>The study suggests that patients with MD experience a reduction in intracranial pressure during acute episodes, and these fluctuations may indicate hearing threshold variations in early-stage of patients.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"195 ","pages":"Article 112658"},"PeriodicalIF":3.3,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145921121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation segmentectomy for treatment of hepatic oligometastases greater than 3 cm","authors":"Qian Yu ,&nbsp;Ali Ahmed ,&nbsp;Wali Badar ,&nbsp;Daniel Kwak ,&nbsp;Aaron William Lyon ,&nbsp;Yating Wang ,&nbsp;Carla Harmath ,&nbsp;Mikin Patel ,&nbsp;Divya Kumari ,&nbsp;Thuong Van Ha ,&nbsp;Osman Ahmed","doi":"10.1016/j.ejrad.2026.112657","DOIUrl":"10.1016/j.ejrad.2026.112657","url":null,"abstract":"<div><h3>Purpose</h3><div>The effectiveness of percutaneous thermoablation as curative treatment of hepatic oligometastases greater than 3 cm can be limited by the ability to achieve adequate ablation coverage. Radiation segmentectomy (RS) using yttrium-90 (Y90) microspheres is an established treatment and potentially curative for hepatocellular carcinoma (HCC) up to 8 cm. This study evaluates the safety and effectiveness of RS for secondary liver tumors larger than 3 cm.</div></div><div><h3>Methods</h3><div>A retrospective review at a single institution was performed from December 2017 to February 2024 to include patients treated with transarterial radioembolization (TARE) for liver metastases using glass Y90 microspheres. RS was defined as a target dose &gt; 200 Gy to no more than two liver segments. The following outcomes were retrieved: overall survival (OS), radiologic response, progression-free survival (PFS), adverse events, and 3-month serum toxicity.</div></div><div><h3>Results</h3><div>A total of 14 patients (mean age: 64.2 ± 18.5, M:F = 5:9) with secondary liver tumors (mean diameter: 4.7 ± 1.4 cm; single hepatic lesion: 57.1 %[8/14]), including 5 colorectal cancer (35.7 %), 2 renal cell carcinoma (14.3 %), 2 uveal melanoma (14.3 %), 2 adenoid cystic carcinoma (14.3 %), 1 pancreatic adenocarcinoma (7.1 %), 1 endometrial carcinoma (7.1 %), and 1 tonsillar adenocarcinoma (7.1 %). The mean segmentectomy dose was 352.6 ± 149.1 Gy. Response rate and disease control rate were 42.9 % (6/14) and 85.7 % (12/14), respectively. The 1-yr and 3-yr target tumor response rates were 51.4 % (95 %CI: 21.9–74.8 %) and 34.2 % (95 %CI: 7.1–64.9 %), respectively, with a median PFS of 16.3 months 95 %CI: 5.4 months-not reached). The 1-yr and 3-yr OS were 80.8 % (95 %CI: 42.4–94.9 %) and 40.4 % (95 %CI: 9.8–70.2 %), respectively, with a median OS of 24.3 months (95 %CI: 8.9-not reached). One patient developed grade 3 thrombocytopenia, requiring holding of systemic treatment (7.1 %). No additional grade 3 or above adverse events occurred.</div></div><div><h3>Conclusion</h3><div>Preliminary results suggest that RS is a feasible treatment option for secondary liver tumors &gt; 3 cm with few major adverse events.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112657"},"PeriodicalIF":3.3,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic navigation-assisted radio-frequency ablation of lung tumors: a pilot study","authors":"Yi Fang ,&nbsp;Milan Sigdel ,&nbsp;Manoj Sigdel ,&nbsp;Madan Sigdel ,&nbsp;Roshan Bhattarai ,&nbsp;Mikias Legesse Gebremedhin ,&nbsp;Zhanguo Sun ,&nbsp;Xinwei Han ,&nbsp;Dechao Jiao","doi":"10.1016/j.ejrad.2026.112655","DOIUrl":"10.1016/j.ejrad.2026.112655","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the feasibility and safety of percutaneous radiofrequency ablation (RFA) of lung tumors under the guidance of robotic navigation system.</div></div><div><h3>Material and methods</h3><div>From January 2022 to December 2023, 62 cases with solitary lung tumors who underwent RFA procedure at our department and were divided into two groups: the robotic navigation assisted puncture (RNAP) group (n = 26) and manual puncture (MP) group (n = 36). Two groups were compared in terms of technical success (TS), puncture scoring (PS), CT scan times, Total procedure time (TPT), puncture time (PT), radiation exposure (RE), complete ablation (CA) rate and local tumor progression rate (LTP) rate.</div></div><div><h3>Results</h3><div>PS, PT, total number of CT scans, and RE showed significance between patients in the RNAP compared to those in the MP group (15/8/2/1 vs. 6/8/18/4, P = <strong>&lt;0.001</strong>; 13.71 min vs. 16.97 mins, P <strong>&lt; 0.01</strong>; 4.57 vs 6.94, P <strong>&lt; 0.01</strong>; 2215.38 vs. 4615 mGy.cm, P <strong>&lt; 0.01</strong>). TS, TPT, major complications, CA rate and LTP rate showed no difference (100 % vs.100 %; 40.52 min vs. 42.53 min; 11.53 % vs. 11.11 %; 88.46 % vs. 86.11 %; 11.53 % % vs. 13.88 %; respectively, and all P &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>Robotic navigation-assisted radiofrequency ablation of lung tumors is a feasible and safe technique. It can minimize needle adjustments, thereby shortening puncture time and reducing radiation exposure for patients.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"195 ","pages":"Article 112655"},"PeriodicalIF":3.3,"publicationDate":"2026-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast enhancement potential of food-based imaging agents in cholangiopancreatography and digestive tract investigations using MRI: A systematic literature review and meta-analysis","authors":"Samuel Dushimirimana ,&nbsp;Edozie Iweka ,&nbsp;Hannah Rickman ,&nbsp;Benard Ohene-Botwe ,&nbsp;Theophilus N. Akudjedu","doi":"10.1016/j.ejrad.2025.112633","DOIUrl":"10.1016/j.ejrad.2025.112633","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the contrast enhancement potential of food-based substances (FBS) as clinical imaging agents in MR cholangiopancreatography (MRCP) and digestive tract investigations.</div></div><div><h3>Methods</h3><div>A systematic literature search was conducted using a pre-defined strategy and inclusion criteria to identify relevant articles<strong>.</strong> Two review authors independently screened and selected papers for inclusion, conducted risk of bias assessment using ROBINS-I (Risk of Bias In Non-randomised Studies of Interventions) tool and assessed certainty of evidence using the Cochrane’s GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Areas of disagreement were resolved through consensus and the involvement of a third reviewer. The data obtained were <em>meta</em>-analysed using both random and fixed effects models with inverse variance methods, depending on the included studies’ methodological heterogeneity, to estimate the pooled mean difference and odds ratio.</div></div><div><h3>Results</h3><div>16 studies (1360 participants) were included in this review. Eight studies each examined the effectiveness of FBS for contrast enhancement in MRCP and MRE, respectively. The pooled mean differences between MRCP with pineapple juice and non-contrast MRCP were 1.04 (95 % CI: 0.23, 1.84; I² = 96 %, p &lt; 0.01) for bile duct visibility and 0.95 (95 % CI: 0.04, 1.85; I² = 95 %, p &lt; 0.01) for pancreatic duct visibility. Compared to non-contrast MRCP, MRCP with pineapple juice showed improved pancreaticobiliary duct visibility (Combined odds ratio, 5.01; 95 % CI: 2.34, 10.64; p &lt; 0.0001). However, when compared with synthetic contrast agents, there is a lower likelihood of obtaining excellent quality MRE images with food-based contrast agents (FBCAs) (odds ratio, 0.36; 95 % CI: 0.18, 0.73, 0.73; p = 0.004). A generally high safety and acceptance profile was reported across the included studies for FBCAs. The certainty of the evidence obtained was considered moderate across all outcomes.</div></div><div><h3>Conclusion</h3><div>Oral administration of pineapple juice improves the diagnostic quality of MRCP investigations, while the contrast enhancement potential of FBS is limited in MRE studies. The high heterogeneity of results and moderate certainty of the evidence, however, require a cautious admission of results. Therefore, further research is necessary to gain a comprehensive understanding of the reliability of FBS in these MRI investigations, as well as in other imaging modalities that are yet to be explored.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"195 ","pages":"Article 112633"},"PeriodicalIF":3.3,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145921188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}