Pub Date : 2026-01-02DOI: 10.1016/j.fitote.2026.107083
Hao Yu , Qiao Wu , Siqi Chen , Yuanyuan Li , Leiling Shi , Zhonghao Sun , Haifeng Wu , Min Ma , Zhaocui Sun , Xudong Xu
Three novel meroterpenoids with unique benzo-fused 10-membered carbocycle skeletons, named tricholactones A-C (1–3), along with four known cyclic dipeptides (4–7), were isolated from the fungus Tricholoma sp. HD0815–7. Their chemical structures and absolute configurations were characterized by comprehensive analysis of HR-ESI-MS, 1D- and 2D-NMR and quantum mechanical electronic circular dichroism (ECD). Compounds 1–3 are novel natural meroterpenoids containing terpenoid scaffolds, phenols units and amino acid residues. Moreover, compound 3 features an unprecedented pentacyclic ring system (8/6/10/5/3) among these 10-membered carbocycle meroterpenoids. All isolated compounds 1–7 were tested for their cytotoxic activity. The results revealed that compound 2 exhibited strong cytotoxicity activity against HGC-27 cells with IC50 values of 2.34 ± 0.32 μM.
{"title":"Three novel meroterpenoids with unique benzo-fused 10-membered carbocycle skeletons from the fungus Tricholoma sp. HD0815–7","authors":"Hao Yu , Qiao Wu , Siqi Chen , Yuanyuan Li , Leiling Shi , Zhonghao Sun , Haifeng Wu , Min Ma , Zhaocui Sun , Xudong Xu","doi":"10.1016/j.fitote.2026.107083","DOIUrl":"10.1016/j.fitote.2026.107083","url":null,"abstract":"<div><div>Three novel meroterpenoids with unique benzo-fused 10-membered carbocycle skeletons, named tricholactones A-C (<strong>1–3</strong>), along with four known cyclic dipeptides (<strong>4–7</strong>), were isolated from the fungus <em>Tricholoma</em> sp. HD0815–7. Their chemical structures and absolute configurations were characterized by comprehensive analysis of HR-ESI-MS, 1D- and 2D-NMR and quantum mechanical electronic circular dichroism (ECD). Compounds <strong>1–3</strong> are novel natural meroterpenoids containing terpenoid scaffolds, phenols units and amino acid residues. Moreover, compound <strong>3</strong> features an unprecedented pentacyclic ring system (8/6/10/5/3) among these 10-membered carbocycle meroterpenoids. All isolated compounds <strong>1–7</strong> were tested for their cytotoxic activity. The results revealed that compound <strong>2</strong> exhibited strong cytotoxicity activity against HGC-27 cells with IC<sub>50</sub> values of 2.34 ± 0.32 μM.</div></div>","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"189 ","pages":"Article 107083"},"PeriodicalIF":2.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-02DOI: 10.1016/j.fitote.2026.107084
Yadong Lv , Guiping Wu , Fenglin Gu , Xin Lu , Jinglin Zhang , Zhiqiang Niu , Xu Wang , Fei Xu , Fenglun Zhang , Xiaode Huang , Yunhe Lian , Zhanjiao Wei , Fu Li , Haifeng Wu , Weicheng Hu
Four previously undescribed alkamides (1–4) were isolated from the fruits of Piper nigrum. Their chemical structures were elucidated using HRESIMS, NMR, and optical rotation analyses. A classical NLRP3 inflammasome activation model was established by priming macrophages with LPS followed by nigericin stimulation. Compounds 1–4 exhibited markedly stronger inhibition than the reference compound piperine. Molecular docking further revealed their binding modes within the NACHT domain of NLRP3. All four derivatives displayed higher docking scores than piperine, with compound 2 showing the strongest predicted binding affinity. Molecular dynamics simulations have verified that the molecule had good binding free energy with NLRP3 and indicated the key amino acids involved in the binding. These findings enrich the structural diversity of piperine derivatives and expand the molecular scaffold available for further structure–activity relationship studies, thereby providing a solid molecular basis for the rational design and synthesis of new piperine-derived NLRP3 inhibitors.
{"title":"Alkamides from Piper nigrum and their potential inhibitory effect on NLRP3 inflammatory activation","authors":"Yadong Lv , Guiping Wu , Fenglin Gu , Xin Lu , Jinglin Zhang , Zhiqiang Niu , Xu Wang , Fei Xu , Fenglun Zhang , Xiaode Huang , Yunhe Lian , Zhanjiao Wei , Fu Li , Haifeng Wu , Weicheng Hu","doi":"10.1016/j.fitote.2026.107084","DOIUrl":"10.1016/j.fitote.2026.107084","url":null,"abstract":"<div><div>Four previously undescribed alkamides (<strong>1</strong>–<strong>4</strong>) were isolated from the fruits of <em>Piper nigrum</em>. Their chemical structures were elucidated using HRESIMS, NMR, and optical rotation analyses. A classical NLRP3 inflammasome activation model was established by priming macrophages with LPS followed by nigericin stimulation. Compounds <strong>1</strong>–<strong>4</strong> exhibited markedly stronger inhibition than the reference compound piperine. Molecular docking further revealed their binding modes within the NACHT domain of NLRP3. All four derivatives displayed higher docking scores than piperine, with compound <strong>2</strong> showing the strongest predicted binding affinity. Molecular dynamics simulations have verified that the molecule had good binding free energy with NLRP3 and indicated the key amino acids involved in the binding. These findings enrich the structural diversity of piperine derivatives and expand the molecular scaffold available for further structure–activity relationship studies, thereby providing a solid molecular basis for the rational design and synthesis of new piperine-derived NLRP3 inhibitors.</div></div>","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"189 ","pages":"Article 107084"},"PeriodicalIF":2.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-02DOI: 10.1016/j.fitote.2026.107082
Abdoulaye Segda , Priya Tufail , Roland Nâg-Tiéro Méda , Aneela Fayaz , Benjamin Kouliga Koama , Georges Anicet Ouédraogo , Humera Jahan , M. Iqbal Choudhary
The present study investigated the antiglycation activities of extracts and fractions of Phyllanthus amarus, Chrysanthellum americanum, Striga hermonthica and, based on cytotoxicity results, evaluated the anti-inflammatory potential of the ethyl acetate fraction of Striga hermonthica (EtOAc-Sh) in AGE-challenged THP-1 monocytes. The in vitro methylglyoxal (MGO)-bovine serum albumin (BSA) assay revealed notable inhibition of AGE formation by EtOAc-Sh (IC50 = 100.1 ± 0.001 μg/mL; quercetin 1.23 μM, gallic acid 0.131 μM, rutin 0.0021 μM), with rutin used as the standard (IC50 = 402 ± 0.30 μM). Cell metabolic assay showed EtOAc-Sh was non-cytotoxic to HepG2 hepatocytes (∼ 94 % cell viability at 250 μg/mL), and THP-1 monocytes (≥ 90 % cell viability at 500 μg/mL). Moreover, EtOAc-Sh significantly (p < 0.001) reduced the AGE-mediated ROS production (83 % at 100 μg/mL), as compared to apocynin (69 % at 100 μM). Furthermore, EtOAc-Sh suppressed the NF-κB (p65) (RFU: 9.18 at 100 μg/mL) activation, as compared to PDTC (RFU: 6.97) at 100 μM. EtOAc-Sh also significantly (p < 0.001) reduced the COX-2 levels (1.52-fold decrease at 100 μg/mL; PDTC, 1.68-fold decrease) in THP-1 monocytes, while significantly (p < 0.001) reversing the AGE-induced suppression of COX-1 levels (1.89-fold increase at 100 μg/mL; PDTC, 1.88-fold increase) at 100 μM. HPLC-UV analysis identified quercetin, gallic acid, and rutin, as the active constituents of the EtOAc-Sh fraction. These findings suggest that EtOAc-Sh fraction as a potential antiglycation, and anti-inflammatory agent, which supporting the traditional use of Striga hermonthica in diabetes management in Burkina Faso.
{"title":"Ethyl acetate fraction of Striga hermonthica (Delile) Benth. inhibits AGEs-mediated inflammatory markers in THP-1 monocytes","authors":"Abdoulaye Segda , Priya Tufail , Roland Nâg-Tiéro Méda , Aneela Fayaz , Benjamin Kouliga Koama , Georges Anicet Ouédraogo , Humera Jahan , M. Iqbal Choudhary","doi":"10.1016/j.fitote.2026.107082","DOIUrl":"10.1016/j.fitote.2026.107082","url":null,"abstract":"<div><div>The present study investigated the antiglycation activities of extracts and fractions of <em>Phyllanthus amarus</em>, <em>Chrysanthellum americanum</em>, <em>Striga hermonthica</em> and, based on cytotoxicity results, evaluated the anti-inflammatory potential of the ethyl acetate fraction of <em>Striga hermonthica</em> (<em>EtOAc-Sh</em>) in AGE-challenged THP-1 monocytes. The <em>in vitro</em> methylglyoxal (MGO)-bovine serum albumin (BSA) assay revealed notable inhibition of AGE formation by <em>EtOAc-Sh</em> (IC<sub>50</sub> = 100.1 ± 0.001 μg/mL; quercetin 1.23 μM, gallic acid 0.131 μM, rutin 0.0021 μM), with rutin used as the standard (IC<sub>50</sub> = 402 ± 0.30 μM). Cell metabolic assay showed <em>EtOAc-Sh</em> was non-cytotoxic to HepG2 hepatocytes (∼ 94 % cell viability at 250 μg/mL), and THP-1 monocytes (≥ 90 % cell viability at 500 μg/mL). Moreover, <em>EtOAc-Sh</em> significantly (<em>p <</em> 0.001) reduced the AGE-mediated ROS production (83 % at 100 μg/mL), as compared to apocynin (69 % at 100 μM). Furthermore, <em>EtOAc-Sh</em> suppressed the NF-κB (p<sup>65</sup>) (RFU: 9.18 at 100 μg/mL) activation, as compared to PDTC (RFU: 6.97) at 100 μM. <em>EtOAc-Sh</em> also significantly (<em>p</em> < 0.001) reduced the COX-2 levels (1.52-fold decrease at 100 μg/mL; PDTC, 1.68-fold decrease) in THP-1 monocytes, while significantly (<em>p</em> < 0.001) reversing the AGE-induced suppression of COX-1 levels (1.89-fold increase at 100 μg/mL; PDTC, 1.88-fold increase) at 100 μM. HPLC-UV analysis identified quercetin, gallic acid, and rutin, as the active constituents of the <em>EtOAc-Sh</em> fraction. These findings suggest that <em>EtOAc-Sh</em> fraction as a potential antiglycation, and anti-inflammatory agent, which supporting the traditional use of <em>Striga hermonthica</em> in diabetes management in Burkina Faso.</div></div>","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"189 ","pages":"Article 107082"},"PeriodicalIF":2.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-02DOI: 10.1016/j.fitote.2026.107087
Yan Li , Tiantian Dong , Tangtang He , Yurong Zhao , Chenxi Yang , Hanlu Xiao , Ruiwen Mo , Jun Chen , Jie Dong
Calvatia lilacina (CL), a traditional Chinese medicinal fungus, has been extensively used for wound healing for centuries. However, the specific effective components of CL remain unclear. This study investigated the phytochemical composition and diabetic wound healing activities of a novel ethanol extract-derived fractions from CL (CLP2). UHPLC-TOF-MS/MS phytochemical analysis revealed 14 active components in CLP2. HPLC analysis showed that ergosterol was the most prevalent component in CLP2, with a content of 837.3 μg/mg. CLP2 significantly accelerated wound healing in db/db diabetic mice, facilitated re-epithelialization and inhibited the polarization of M1 macrophages, downregulated the transcription levels of the inflammatory cytokines, and promoted the expression of anti-inflammatory factors. In vitro tests indicated that CLP2 can promote the proliferation and migration of mouse skin fibroblasts, suppress the expression of M1 macrophage-associated pro-inflammatory cytokines, and enhance M2 polarization. Additionally, in vivo and in vitro experiments confirmed that CLP2 accelerated diabetic wound healing by suppressing M1 macrophages and promoting the polarization of macrophages towards the M2 phenotype, facilitating a faster transition from the inflammatory stage to the proliferative stage. These results highlight CLP2 as a potential therapeutic intervention for diabetic wound healing.
{"title":"Topical application of Calvatia lilacina ethanol extract-derived fraction promotes diabetic wound healing","authors":"Yan Li , Tiantian Dong , Tangtang He , Yurong Zhao , Chenxi Yang , Hanlu Xiao , Ruiwen Mo , Jun Chen , Jie Dong","doi":"10.1016/j.fitote.2026.107087","DOIUrl":"10.1016/j.fitote.2026.107087","url":null,"abstract":"<div><div><em>Calvatia lilacina</em> (CL), a traditional Chinese medicinal fungus, has been extensively used for wound healing for centuries. However, the specific effective components of CL remain unclear. This study investigated the phytochemical composition and diabetic wound healing activities of a novel ethanol extract-derived fractions from CL (CLP2). UHPLC-TOF-MS/MS phytochemical analysis revealed 14 active components in CLP2. HPLC analysis showed that ergosterol was the most prevalent component in CLP2, with a content of 837.3 μg/mg. CLP2 significantly accelerated wound healing in db/db diabetic mice, facilitated re-epithelialization and inhibited the polarization of M1 macrophages, downregulated the transcription levels of the inflammatory cytokines, and promoted the expression of anti-inflammatory factors. <em>In vitro</em> tests indicated that CLP2 can promote the proliferation and migration of mouse skin fibroblasts, suppress the expression of M1 macrophage-associated pro-inflammatory cytokines, and enhance M2 polarization. Additionally, <em>in vivo</em> and <em>in vitro</em> experiments confirmed that CLP2 accelerated diabetic wound healing by suppressing M1 macrophages and promoting the polarization of macrophages towards the M2 phenotype, facilitating a faster transition from the inflammatory stage to the proliferative stage. These results highlight CLP2 as a potential therapeutic intervention for diabetic wound healing.</div></div>","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"189 ","pages":"Article 107087"},"PeriodicalIF":2.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-02DOI: 10.1016/j.fitote.2026.107085
Yuxin Xie , Gaoyang Lin , Chuanlong Guo , Jin Tian , Lin Long , Lili Zhao , Longjiang Huang , Hongmei Wei , Jun Xiao , Xuemao Liu
This study aims to elucidate the molecular mechanisms by which the traditional Chinese medicine Gu-Jin-Xiao-Ji Decoction (GJXJD) enhances the anti-tumor efficacy of PD-1 inhibitors in lung cancer and to characterize its major chemical components. The major components of GJXJD were identified and quantitatively analyzed using ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS). A mouse Lewis lung carcinoma (LLC) subcutaneous xenograft model was established, and high-throughput transcriptome sequencing was performed. Combined treatment with GJXJD and a PD-1 inhibitor significantly suppressed tumor growth, achieving a tumor inhibition rate of 54.48 %, which was substantially higher than that of either monotherapy (GJXJD: 27.58 %; anti-PD-1: 25.76 %). Transcriptomic analysis indicated notable enrichment and downregulation of the PI3K/AKT signaling pathway. Immunohistochemistry revealed inhibition of the PI3K/AKT/NF-κB axis and subsequent downregulation of PD-L1 expression. GJXJD treatment increased spleen and thymus indices, reduced serum IL-17 levels by approximately 40 %, and promoted the secretion of IL-2, IFN-γ, and TNF-α by about 1.5- to 2-fold. Enhanced infiltration of CD3+, CD4+, and CD8+ T cells were observed in tumor tissues, with CD8+ T cell infiltration increasing by over 3-fold in the combination group. H&E staining showed no significant pathological changes in major organs. These findings demonstrate that GJXJD potentiates the anti-tumor effect of PD-1 inhibitors by inhibiting the PI3K/AKT/NF-κB pathway, reducing PD-L1 expression, and ameliorating immune evasion. The identified active components provide a chemical basis for its efficacy, supporting GJXJD as a promising adjuvant agent for lung cancer immunotherapy.
{"title":"Gu-Jin-Xiao-Ji Decoction potentiates anti-PD-1 immunotherapy in lung cancer by inhibiting the PI3K/AKT/NF-κB/PD-L1 axis","authors":"Yuxin Xie , Gaoyang Lin , Chuanlong Guo , Jin Tian , Lin Long , Lili Zhao , Longjiang Huang , Hongmei Wei , Jun Xiao , Xuemao Liu","doi":"10.1016/j.fitote.2026.107085","DOIUrl":"10.1016/j.fitote.2026.107085","url":null,"abstract":"<div><div>This study aims to elucidate the molecular mechanisms by which the traditional Chinese medicine Gu-Jin-Xiao-Ji Decoction (GJXJD) enhances the anti-tumor efficacy of PD-1 inhibitors in lung cancer and to characterize its major chemical components. The major components of GJXJD were identified and quantitatively analyzed using ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS). A mouse Lewis lung carcinoma (LLC) subcutaneous xenograft model was established, and high-throughput transcriptome sequencing was performed. Combined treatment with GJXJD and a PD-1 inhibitor significantly suppressed tumor growth, achieving a tumor inhibition rate of 54.48 %, which was substantially higher than that of either monotherapy (GJXJD: 27.58 %; anti-PD-1: 25.76 %). Transcriptomic analysis indicated notable enrichment and downregulation of the PI3K/AKT signaling pathway. Immunohistochemistry revealed inhibition of the PI3K/AKT/NF-κB axis and subsequent downregulation of PD-L1 expression. GJXJD treatment increased spleen and thymus indices, reduced serum IL-17 levels by approximately 40 %, and promoted the secretion of IL-2, IFN-γ, and TNF-α by about 1.5- to 2-fold. Enhanced infiltration of CD3<sup>+</sup>, CD4<sup>+</sup>, and CD8<sup>+</sup> T cells were observed in tumor tissues, with CD8<sup>+</sup> T cell infiltration increasing by over 3-fold in the combination group. H&E staining showed no significant pathological changes in major organs. These findings demonstrate that GJXJD potentiates the anti-tumor effect of PD-1 inhibitors by inhibiting the PI3K/AKT/NF-κB pathway, reducing PD-L1 expression, and ameliorating immune evasion. The identified active components provide a chemical basis for its efficacy, supporting GJXJD as a promising adjuvant agent for lung cancer immunotherapy.</div></div>","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"189 ","pages":"Article 107085"},"PeriodicalIF":2.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.fitote.2025.106991
Shihao Zhang , Ding Liu , Dongyan Guo , Chongbo Zhao , Yajun Shi , Junbo Zou , Huanxian Shi , Jiangxue Cheng , Jing Sun , Xiaofei Zhang
{"title":"Corrigendum to “Pharmacodynamic effects and mechanism of Pueraria lobata-Schisandra chinensis combination in the treatment of alcoholic liver disease” [Fitoterapia 187 (2025) 106873]","authors":"Shihao Zhang , Ding Liu , Dongyan Guo , Chongbo Zhao , Yajun Shi , Junbo Zou , Huanxian Shi , Jiangxue Cheng , Jing Sun , Xiaofei Zhang","doi":"10.1016/j.fitote.2025.106991","DOIUrl":"10.1016/j.fitote.2025.106991","url":null,"abstract":"","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"188 ","pages":"Article 106991"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145548837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.fitote.2025.107037
Wei Su , Hanwen Yuan , Muhammad Aamer , Xudong Zhou , Kang Zhou , Ling Li , Yupei Yang , Qingling Xie , Shiqi Liu , Gang Fu , Yu Mao , Bin Li , Wei Wang
{"title":"Corrigendum to “Isolation and characterization of xuetonlignans L-P, previously undescribed spirobenzofuranoid dibenzocyclooctadiene lignans from the fruits of Kadsura heteroclita” [Fitoterapia 185 (2025) 106726]","authors":"Wei Su , Hanwen Yuan , Muhammad Aamer , Xudong Zhou , Kang Zhou , Ling Li , Yupei Yang , Qingling Xie , Shiqi Liu , Gang Fu , Yu Mao , Bin Li , Wei Wang","doi":"10.1016/j.fitote.2025.107037","DOIUrl":"10.1016/j.fitote.2025.107037","url":null,"abstract":"","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"188 ","pages":"Article 107037"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.fitote.2025.106953
Mahmoud Moustafa , Walaa S. Aboelmaaty , Weaam Ebrahim , Reham Hassan Mekky , Mohamed A. Tammam , Amr El-Demerdash , Ahmed M. Zaghloul
{"title":"Corrigendum to “Chemical profiling of Lycium shawii via RP-HPLC-QTOF-MS and MS/MS: Unveiling its in-vivo wound-healing potential supported by molecular docking investigations” [Fitoterapia 185 (2025) 106749]","authors":"Mahmoud Moustafa , Walaa S. Aboelmaaty , Weaam Ebrahim , Reham Hassan Mekky , Mohamed A. Tammam , Amr El-Demerdash , Ahmed M. Zaghloul","doi":"10.1016/j.fitote.2025.106953","DOIUrl":"10.1016/j.fitote.2025.106953","url":null,"abstract":"","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":"188 ","pages":"Article 106953"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号