European review for medical and pharmacological sciences最新文献

Objective: The aim of this study was to observe the clinical efficacy and safety of minimally invasive posterior cervical foraminotomy (MI-PCF) and anterior cervical discectomy and fusion (ACDF) in the treatment of single-level unilateral cervical radiculopathy (SLUCR).

Patients and methods: We retrospectively analyzed 81 patients with SLUCR in two hospitals from February 2020 to February 2022, including the MI-PCF group (n=40) and the ACDF group (n=41). The differences in neck and shoulder pain, visual analog score (VAS), upper limb radiating pain (VAS), and neck disability index (NDI) were compared. Operative time, intraoperative bleeding, hospital stay, and complications were also compared between the two groups.

Results: The degree of neck and shoulder pain relief at 1 day postoperatively was better in the ACDF group than in the MI-PCF group (p<0.05), while there were no significant differences between the two groups in terms of neck and shoulder pain relief at 1 month, 3 months, 6 months, and 12 months postoperatively, (p>0.05). There were no significant differences in the relief of upper limb radiating pain and the decrease of NDI scores between the two groups at 1 day, 1 month, 3 months, 6 months, and 12 months after surgery (p>0.05). The patients in MI-PCF group had shorter operative time, less bleeding, and shorter hospital stay, which were statistically different (p<0.05). There was no statistical difference in the complication rate between the two groups, (p>0.05).

Conclusions: The clinical efficacy and safety of MI-PCF and ACDF in the treatment of SLUCR are satisfactory, meanwhile, MI-PCF has shorter operative time, less bleeding and shorter hospital stay than ACDF, which is worthy of clinical promotion.

Objective: The study aimed to evaluate the effect of the SYNTAX score (SS) calculated before percutaneous intervention on survival in a group of young patients with acute coronary syndrome (ACS).

Patients and methods: Our study is a retrospective study. Patients between the ages of 18 and 45 who applied to Private Yalova Atakent Hospital Cardiology Clinic with ACS and underwent percutaneous coronary intervention between 01.01.2017 and 01.12.2023 were included in the study. Patients aged 45 and under who presented with acute syndrome and underwent coronary angiography were evaluated. Patients' history of major cardiac adverse events (MACE) was evaluated. Demographic characteristics, laboratory findings, echocardiographic parameters, and SS of the patients were recorded. SS was calculated from the coronary angiography images of the patients.

Results: 140 patients were included in the study. 70.0% (n=98) of the cases were diagnosed with ST-elevation myocardial infarction (STE-MI), 28.6% (n=40) with non-ST-elevation myocardial infarction (NSTE-MI)-unstable angina pectoris (USAP), and 1.4% with cardiac arrest (n=2). 28.6% (n=40) of the patients had MACE. There was a statistically significant correlation between SS and MACE (r=0.525 p=0.001). An SS value of 23.15 had 77.5% sensitivity and 60.8% specificity in predicting MACE. There was a statistically significant negative correlation between SS and ejection fraction (EF) (r=-0.584, p=0.001). EF<40.5 predicted mortality with 77.7% sensitivity and 69.4% specificity (AUC 0.710, p=0.01, 95% CI 0.615-0.825).

Conclusions: SYNTAX Score and EF have predictive value in predicting MACE and mortality in young ACS patients. Different scoring systems are needed to predict MACE and mortality after ACS in young patients.

The article "Regulation of miRNAs on c-met protein expression in ovarian cancer and its implication", by H. Liu, S.-R. Li, Q. Si, published in Eur Rev Med Pharmacol Sci 2017; 21 (15): 3353-3359-PMID: 28829508 has been retracted by the Editor in Chief. Following some concerns raised on PubPeer regarding a possible manipulation in Figure 5 (link: https://pubpeer.com/publications/7B6E6E6679990661654EBCAF472921), the Editor in Chief has started an investigation to assess the validity of the results as well as possible figure manipulation. The authors were informed about the journal's investigation but remained unresponsive and have not provided the manuscript's raw data. The journal's investigation revealed a figure overlap between panels pcDNA3.1-EGFP and pcDNA3.1-EGFP-204-up in Figure 5. Consequently, the Editor in Chief mistrusts the results presented and has decided to retract the article. This article has been retracted. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/13200.

Objective: Viral infections are an important cause of exacerbation in bronchiectasis patients. We aimed to determine the influence of the COVID-19 pandemic on adult bronchiectasis patients and whether there was a relationship between the clinical parameters and the COVID-19 infection.

Patients and methods: In this retrospective observational study, 547 bronchiectasis patients were included. Demographic characteristics, vaccination status, Bronchiectasis Severity Index (BSI), FACED and Reiff scores, and clinical and laboratory parameters during COVID-19 infection were evaluated.

Results: The median age was 56, and 49.2% of the patients were male. The COVID-19 infection rate was 27.6%. 431 (78.8%) patients had at least one dose of the COVID-19 vaccine. The patients were divided into two groups according to their COVID-19 infection status. Emergency admission was significantly higher in the COVID-19-infected group. There was no statistical difference with other clinical factors. The COVID-19-infected patients were divided into home treatment and hospital/intensive care unit (ICU) treatment groups. There was a statistically significant difference between the two groups regarding advanced age, male gender, presence of asthma, long-term oxygen therapy (LTOT) and non-invasive mechanic ventilator (NIMV) usage, sputum culture positivity, BSI and FACED scores, and multiple laboratory parameters (ferritin, C-reactive protein, eosinophil). In logistic regression analysis, BSI was found as a risk factor [OR 1.252 (1.077-1.456), p=0.004] and eosinophilia as a protective factor [OR 0.986 (0.973-0.999), p=0.030] for hospital/ICU admission.

Conclusions: Frequent emergency visits might increase the risk of COVID-19 infection in bronchiectasis patients. BSI was found to be an independent risk factor, and blood eosinophilia could play a protective role in hospital/ICU admission for COVID-19 infection.

The article "Imipenem-resistance in Serratia marcescens is mediated by plasmid expression of KPC-2", by W.-Q. Su, Y.-Q. Zhu, N.-M. Deng, L. Li, published in Eur Rev Med Pharmacol Sci 2017; 21 (7): 1690- 1694-PMID: 28429335 has been retracted by the Editor in Chief. Following some concerns raised on PubPeer (link: https://pubpeer.com/publications/F7E91E2863540C7CB030B86E16917F), the Editor in Chief has started an investigation to assess the validity of the results as well as possible figure and data manipulation. The authors were informed about the journal's investigation but have remained unresponsive and have not provided the manuscript's raw data. Therefore, the validity of the overall results could not be verified. The journal's investigation revealed that Figures 2 and 3 have been computer-generated. Additionally, Figure 1 was duplicated from a previously published article. Moreover, several terminology inaccuracies were identified within the manuscript. Consequently, the Editor in Chief mistrusts the results presented and has decided to retract the article. This article has been retracted. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/12540.

The article "LINC01116 promotes the proliferation and inhibits the apoptosis of gastric cancer cells" by J. Chen, Z.-H. Yuan, X.-H. Hou, M.-H. Shi, R. Jiang, published in Eur Rev Med Pharmacol Sci 2020; 24 (4): 1807-1814-DOI: 10.26355/eurrev_202002_20358-PMID: 32141549 has been retracted by the Editor in Chief. Following the journal's investigation, due to concerns raised regarding non-verifiable nucleotide sequences and cell lines used in the article, the editorial team has contacted the authors to provide a reply regarding the above-mentioned issues. The authors revealed that they suspected errors in the experimental process as early as 2021. After repeated literature reviews and reproducibility experiments, the authors still believe that the paper's conclusions are inaccurate and need further revision. Consequently, the Editor in Chief mistrusts the results presented and has decided to retract the article. This article has been retracted. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/20358.

The article "Interferon-γ affects leukemia cell apoptosis through regulating Fas/FasL signaling pathway" by H.-L. Xia, C.-J. Li, X.-F. Hou, H. Zhang, Z.-H. Wu, J. Wang, published in Eur Rev Med Pharmacol Sci 2017; 21 (9): 2244-2248 - PMID: 28537657 has been retracted by the Editor in Chief. Following some concerns raised on PubPeer (link: https://pubpeer.com/publications/2F360E066992B4078059C72F8530B3), the Editor in Chief has started an investigation to assess the validity of the results as well as possible figure manipulation. The authors have been informed about the journal's investigation but remained unresponsive and have not provided the study's raw data. The journal's investigation revealed a duplicated area in Figure 1 between panels 100 U/mL and 1000 U/mL. Consequently, the Editor in Chief mistrusts the results presented and has decided to retract the article. This article has been retracted. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/12706.

The article "Valsartan reduces AT1-AA-induced apoptosis through suppression oxidative stress mediated ER stress in endothelial progenitor cells" by Z.-C. Wang, J. Qi, L.-M. Liu, J. Li, H.-Y. Xu, B. Liang, B. Li, published in Eur Rev Med Pharmacol Sci 2017; 21 (5): 1159-1168 - PMID: 28338173 has been retracted by the Editor in Chief. Following some concerns raised on PubPeer (link: https://pubpeer.com/publications/8FA8D4C63DE61DDB6C89537AD04B24), the Editor in Chief has started an investigation to assess the validity of the results as well as possible figure manipulation. The authors have been informed about the journal's investigation but remained unresponsive and have not provided the study's raw data. The journal's investigation revealed a Figure duplication in Figure 2C between panels AT1-AA (2.5 µM), AT1-AA (5 µM), AT1-AA (10 µM), and AT1-AA+Valsartan. Consequently, the Editor in Chief mistrusts the results presented and has decided to retract the article. This article has been retracted. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/12342.

The article "Study on the expression and mechanism of inflammatory factors in the brain of rats with cerebral vasospasm" by Q. Huang, G. Wang, Y.-L. Hu, J.-X. Liu, J. Yang, S. Wang, H.-B. Zhang, published in Eur Rev Med Pharmacol Sci 2017; 21 (12): 2887-2894 - PMID: 28682429 has been retracted by the Editor in Chief. Following some concerns raised on PubPeer (link: https://pubpeer.com/publications/48E37B385D83F1B09741B2B06B39C3), the Editor in Chief has started an investigation to assess the validity of the results as well as possible figure manipulation. The authors have been informed about the journal's investigation but remained unresponsive and have not provided the study's raw data. The journal's investigation uncovered a duplication between Figure 2A and Figure 1D with a previously published article (https://doi.org/10.1371/journal.pone.0096212). Additionally, duplications were identified between panels b, c, d, f, g, and h of Figure 3A and Figure 6B, C, D, F, G, and H, respectively, of the same previously published article (https://doi.org/10.1371/journal.pone.0096212). Consequently, the Editor in Chief mistrusts the results presented and has decided to retract the article. This article has been retracted. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/12948.

Objective: Assisted Reproductive Technologies (ART) are considered to be the most effective treatment option for unexplained infertility. This study aims to investigate the pregnancy outcomes of women who received in-vitro fertilization-embryo transfer (IVF-ET) treatment for unexplained infertility and the contributing factors affecting these outcomes.

Patients and methods: The present study included 789 consecutive women with unexplained infertility who were treated with IVF-ET at the ART Clinic of the Health Sciences University, Ankara Etlik Zübeyde Hanım Gynecology Training and Research Hospital between January 2007 and December 2019. The contributing factors affecting these outcomes, such as body mass index (BMI), basal follicle-stimulating hormone (FSH), and antimullerian hormone (AMH), were evaluated retrospectively.

Results: Clinical pregnancy per cycle was 19.8% among patients recruited. No statistically significant difference was detected in terms of age, infertility duration, and BMI of the patients who achieved pregnancy and who failed to get pregnant after IVF-ET treatment. The basal FSH level was found to be significantly lower (p=0.001), and the AMH level was significantly higher in patients who had clinical pregnancy (p=0.001). The basal AMH cut-off value was calculated to be 3.34 ng/mL, and the basal FSH cut-off value was calculated as 7.26 IU/L for the prediction of clinical pregnancy.

Conclusions: IVF-ET treatment can be applied as a successful treatment option in unexplained infertility cases. Although the basal FSH and AMH values ​are not the cut-off values that have high sensitivity and specificity, they are considered to be associated with pregnancy rates.