Pub Date : 2026-02-20DOI: 10.1016/j.fertnstert.2026.02.024
Jose Carugno, Nash S. Moawad, Emad Mikhail
{"title":"Operating in Two Worlds: Gynecologic Surgery for the Gravid Uterus","authors":"Jose Carugno, Nash S. Moawad, Emad Mikhail","doi":"10.1016/j.fertnstert.2026.02.024","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2026.02.024","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"18 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146777367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-20DOI: 10.1016/j.fertnstert.2026.02.025
Kiley Hunkler, David Boedeker, Kelby Bulles, Joshua Combs, Jill Brown
{"title":"Preimplantation genetic testing for BRCA-1 and risk-reducing surgery is more cost-effective at age 35 than age 40","authors":"Kiley Hunkler, David Boedeker, Kelby Bulles, Joshua Combs, Jill Brown","doi":"10.1016/j.fertnstert.2026.02.025","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2026.02.025","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"9 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146777368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-19DOI: 10.1016/j.fertnstert.2026.02.023
Lan N Vuong, Minh H N Nguyen, Toan D Pham, Nghia A Nguyen, Nam T Nguyen, Van T T Tran, Tuong M Ho
{"title":"Development of children born from capacitation in vitro maturation vs. in vitro fertilization: 5-year follow-up of a randomized controlled trial.","authors":"Lan N Vuong, Minh H N Nguyen, Toan D Pham, Nghia A Nguyen, Nam T Nguyen, Van T T Tran, Tuong M Ho","doi":"10.1016/j.fertnstert.2026.02.023","DOIUrl":"10.1016/j.fertnstert.2026.02.023","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146776196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-18DOI: 10.1016/j.fertnstert.2026.02.019
Suzan Abd Elgani, Adi Dayan-Schwartz, Maya Muhlbauer Avni, David Danon, Liron Kogan
<p><strong>Objective: </strong>To describe the diagnostic process and a structured, stepwise laparoscopic excision of a noncommunicating rudimentary uterine horn containing an ongoing pregnancy with cardiac activity, demonstrating how expert transvaginal and 3-dimensional ultrasound can guide early diagnosis and safe minimally invasive surgical management.</p><p><strong>Design: </strong>Detailed case report with diagnostic imaging, stepwise operative video, and structured 5-step surgical technique.</p><p><strong>Subjects: </strong>A 31-year-old G2P1 woman with a history of a prior low-transverse cesarean delivery presented to the emergency department with suspected ectopic pregnancy. She was hemodynamically stable with no active vaginal bleeding or acute abdominal pain. Detailed history revealed asymptomatic presentation; routine first-trimester ultrasound performed for dating had raised suspicion of an ectopic pregnancy. On physical examination, the cervix was single and the os closed; bimanual examination revealed mild adnexal tenderness on the left but no peritoneal signs. TVUS performed by a radiologist with expertise in complex pelvic anomalies demonstrated a right unicornuate uterus with normal endometrial thickness and no intrauterine gestational sac. A separate, left-sided gestational sac measuring 20 mm was identified, surrounded by a thick myometrial mantle (approximately 15 mm), with no continuity to the endometrial cavity or main uterine cornu. The gestational sac contained a yolk sac and a fetal pole, with a crown-rump length consistent with approximately 7 weeks and 6 days of gestation, and demonstrated confirmed cardiac activity. Color and spectral Doppler demonstrated robust arterial flow surrounding the gestational sac, indicating a rich vascular supply to the rudimentary horn. Three-dimensional ultrasound reconstructions confirmed the uterine anatomy as unicornuate with a noncommunicating rudimentary horn. Given the early gestational age, hemodynamic stability, clear diagnostic features on expert transvaginal and 3D ultrasound (single cervix, noncommunicating sac, robust vascularity, known unicornuate anatomy), and the time-sensitive nature of the condition, same-day laparoscopic management was chosen. Preoperative magnetic resonance imaging (MRI) was not pursued because transvaginal ultrasound provided clear anatomic delineation, including characterization of the attachment between the rudimentary horn and the unicornuate uterus, assessment of vascular supply, and evaluation of surrounding pelvic anatomy for surgical planning. Medical management with methotrexate was considered inappropriate, as it was unlikely to provide definitive treatment and carried a risk of treatment prolongation and unexpected rupture. This management aligns with published case series where expert ultrasound diagnosis is confirmed intraoperatively, and MRI is reserved as an adjunct in cases of diagnostic uncertainty (1-3).</p><p><strong>Intervention: </
{"title":"Laparoscopic excision of a noncommunicating rudimentary horn containing an ongoing pregnancy with cardiac activity: a structured minimally invasive approach.","authors":"Suzan Abd Elgani, Adi Dayan-Schwartz, Maya Muhlbauer Avni, David Danon, Liron Kogan","doi":"10.1016/j.fertnstert.2026.02.019","DOIUrl":"10.1016/j.fertnstert.2026.02.019","url":null,"abstract":"<p><strong>Objective: </strong>To describe the diagnostic process and a structured, stepwise laparoscopic excision of a noncommunicating rudimentary uterine horn containing an ongoing pregnancy with cardiac activity, demonstrating how expert transvaginal and 3-dimensional ultrasound can guide early diagnosis and safe minimally invasive surgical management.</p><p><strong>Design: </strong>Detailed case report with diagnostic imaging, stepwise operative video, and structured 5-step surgical technique.</p><p><strong>Subjects: </strong>A 31-year-old G2P1 woman with a history of a prior low-transverse cesarean delivery presented to the emergency department with suspected ectopic pregnancy. She was hemodynamically stable with no active vaginal bleeding or acute abdominal pain. Detailed history revealed asymptomatic presentation; routine first-trimester ultrasound performed for dating had raised suspicion of an ectopic pregnancy. On physical examination, the cervix was single and the os closed; bimanual examination revealed mild adnexal tenderness on the left but no peritoneal signs. TVUS performed by a radiologist with expertise in complex pelvic anomalies demonstrated a right unicornuate uterus with normal endometrial thickness and no intrauterine gestational sac. A separate, left-sided gestational sac measuring 20 mm was identified, surrounded by a thick myometrial mantle (approximately 15 mm), with no continuity to the endometrial cavity or main uterine cornu. The gestational sac contained a yolk sac and a fetal pole, with a crown-rump length consistent with approximately 7 weeks and 6 days of gestation, and demonstrated confirmed cardiac activity. Color and spectral Doppler demonstrated robust arterial flow surrounding the gestational sac, indicating a rich vascular supply to the rudimentary horn. Three-dimensional ultrasound reconstructions confirmed the uterine anatomy as unicornuate with a noncommunicating rudimentary horn. Given the early gestational age, hemodynamic stability, clear diagnostic features on expert transvaginal and 3D ultrasound (single cervix, noncommunicating sac, robust vascularity, known unicornuate anatomy), and the time-sensitive nature of the condition, same-day laparoscopic management was chosen. Preoperative magnetic resonance imaging (MRI) was not pursued because transvaginal ultrasound provided clear anatomic delineation, including characterization of the attachment between the rudimentary horn and the unicornuate uterus, assessment of vascular supply, and evaluation of surrounding pelvic anatomy for surgical planning. Medical management with methotrexate was considered inappropriate, as it was unlikely to provide definitive treatment and carried a risk of treatment prolongation and unexpected rupture. This management aligns with published case series where expert ultrasound diagnosis is confirmed intraoperatively, and MRI is reserved as an adjunct in cases of diagnostic uncertainty (1-3).</p><p><strong>Intervention: </","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-18DOI: 10.1016/j.fertnstert.2026.01.013
Allison Eubanks, Kurt T Barnhart
{"title":"Responsible use of artificial intelligence in manuscript preparation: guidance from Fertility and Sterility.","authors":"Allison Eubanks, Kurt T Barnhart","doi":"10.1016/j.fertnstert.2026.01.013","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2026.01.013","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-17DOI: 10.1016/j.fertnstert.2026.01.006
ASRM Ethics Committee, Sigal Klipstein M.D., Sina Abhari M.D., Paula Amato M.D., Aishwarya Arjunan M.S. M.P.H., Tolulope Bakare M.D., Kim Bergman Ph.D., Michelle Bayefsky M.D., Zeki Beyhan Ph.D., Katherine Cameron M.D., Susan Crockin J.D., Jessica Goldstein R.N., Insoo Hyun Ph.D., Jennifer Kawwass M.D., Joshua Morris M.D., Jeanne O’Brien M.D., Torie Comeaux Plowden M.D. M.P.H., Gwendolyn Quinn Ph.D., Robert Rebar M.D., Jared Robins M.D. M.B.A., Chevis N. Shannon Dr.PH. M.P.H. M.B.A., Michael Thomas M.D., Sean Tipton M.A.
In vitro gametogenesis represents a potentially groundbreaking advancement in reproductive medicine, but one that faces major challenges before it can be implemented in humans. Scientific, ethical, and societal implications must be carefully considered before clinical application.
{"title":"Ethical considerations of in vitro gametogenesis: an Ethics Committee opinion","authors":"ASRM Ethics Committee, Sigal Klipstein M.D., Sina Abhari M.D., Paula Amato M.D., Aishwarya Arjunan M.S. M.P.H., Tolulope Bakare M.D., Kim Bergman Ph.D., Michelle Bayefsky M.D., Zeki Beyhan Ph.D., Katherine Cameron M.D., Susan Crockin J.D., Jessica Goldstein R.N., Insoo Hyun Ph.D., Jennifer Kawwass M.D., Joshua Morris M.D., Jeanne O’Brien M.D., Torie Comeaux Plowden M.D. M.P.H., Gwendolyn Quinn Ph.D., Robert Rebar M.D., Jared Robins M.D. M.B.A., Chevis N. Shannon Dr.PH. M.P.H. M.B.A., Michael Thomas M.D., Sean Tipton M.A.","doi":"10.1016/j.fertnstert.2026.01.006","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2026.01.006","url":null,"abstract":"In vitro gametogenesis represents a potentially groundbreaking advancement in reproductive medicine, but one that faces major challenges before it can be implemented in humans. Scientific, ethical, and societal implications must be carefully considered before clinical application.","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"11 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146209072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-17DOI: 10.1016/j.fertnstert.2026.02.021
Christos Venetis, Kokkoni Kiose, Maria Apostolidou, Evangelia Katsika, Julia Bosdou, George Lainas, Efstratios Kolibianakis
<p><strong>Importance: </strong>Frozen-thawed embryo transfer cycles have risen substantially. Synchronization between the embryo and endometrium is achieved via natural or artificial hormonal preparation. Emerging data associate artificial regimens with hypertensive disorders, potentially favoring natural cycles. Because of their limited scheduling flexibility, modified natural cycles (mNCs) have been proposed, although equivalence in live birth outcomes remains unconfirmed.</p><p><strong>Objective: </strong>To identify whether there is a difference in the probability of live birth between women undergoing frozen embryo transfer (FET) in the mNC and those in the natural cycle (NC).</p><p><strong>Data sources: </strong>A literature search was conducted until October 2024 in MEDLINE, Embase, Cochrane CENTRAL, Scopus, Web of Science and Clinicaltrials.gov to identify eligible randomized controlled trials (RCTs).</p><p><strong>Study selection and synthesis: </strong>Data were independently extracted by three reviewers. Quality and trustworthiness were assessed using the RoB2 tool and the Trustworthiness in RAndomised Controlled Trials (TRACT) checklist, respectively. Sensitivity analysis was performed by excluding studies with a high risk of bias. Meta-analysis was performed using the random or fixed effects model depending on the presence or absence of significant statistical (I<sup>2</sup>>50%) or clinical heterogeneity.</p><p><strong>Main outcomes: </strong>The primary outcome was live birth. Secondary outcomes included clinical and ongoing pregnancy, cycle cancellation, and miscarriage.</p><p><strong>Results: </strong>Six RCTs (n = 1,708) (published between 2010 and 2024) were identified. Three RCTs were deemed to have a high risk of bias. All studies were considered trustworthy for inclusion in the meta-analysis according to the TRACT checklist. No significant difference was observed in live birth rates (risk ratio [RR]: 0.93, 95% confidence interval [CI]: 0.74-1.17; I<sup>2</sup> = 0%, 4 studies, n = 1,280; [sensitivity analysis: RR: 0.90, 95% CI: 0.32-2.52; I<sup>2</sup> = 0%, 2 studies, n = 1,060]), ongoing pregnancy rates (RR: 0.74, 95% CI: 0.37-1.51; I<sup>2</sup> = 1%, 3 studies, n = 536), and clinical pregnancy rates (RR: 0.86, 95% CI: 0.67-1.10; I<sup>2</sup> = 0%, 4 studies, n = 648). Similarly, no significant difference was observed in cycle cancellation rates and miscarriage rates. The sensitivity analysis, performed by excluding the three studies deemed to be at high risk of bias, did not materially alter the results obtained for all the aforementioned outcomes.</p><p><strong>Conclusion and relevance: </strong>Clinicians and patients should be informed that, on the basis of the best available evidence, frozen-thawed embryo transfer in mNC results in comparable live birth rates with NC, making it a pragmatic option for scheduling or convenience.</p><p><strong>Trial registration: </strong>The protocol for the systematic review was reg
{"title":"Modified natural vs. natural cycle for endometrial preparation in frozen embryo transfer: a meta-analysis.","authors":"Christos Venetis, Kokkoni Kiose, Maria Apostolidou, Evangelia Katsika, Julia Bosdou, George Lainas, Efstratios Kolibianakis","doi":"10.1016/j.fertnstert.2026.02.021","DOIUrl":"10.1016/j.fertnstert.2026.02.021","url":null,"abstract":"<p><strong>Importance: </strong>Frozen-thawed embryo transfer cycles have risen substantially. Synchronization between the embryo and endometrium is achieved via natural or artificial hormonal preparation. Emerging data associate artificial regimens with hypertensive disorders, potentially favoring natural cycles. Because of their limited scheduling flexibility, modified natural cycles (mNCs) have been proposed, although equivalence in live birth outcomes remains unconfirmed.</p><p><strong>Objective: </strong>To identify whether there is a difference in the probability of live birth between women undergoing frozen embryo transfer (FET) in the mNC and those in the natural cycle (NC).</p><p><strong>Data sources: </strong>A literature search was conducted until October 2024 in MEDLINE, Embase, Cochrane CENTRAL, Scopus, Web of Science and Clinicaltrials.gov to identify eligible randomized controlled trials (RCTs).</p><p><strong>Study selection and synthesis: </strong>Data were independently extracted by three reviewers. Quality and trustworthiness were assessed using the RoB2 tool and the Trustworthiness in RAndomised Controlled Trials (TRACT) checklist, respectively. Sensitivity analysis was performed by excluding studies with a high risk of bias. Meta-analysis was performed using the random or fixed effects model depending on the presence or absence of significant statistical (I<sup>2</sup>>50%) or clinical heterogeneity.</p><p><strong>Main outcomes: </strong>The primary outcome was live birth. Secondary outcomes included clinical and ongoing pregnancy, cycle cancellation, and miscarriage.</p><p><strong>Results: </strong>Six RCTs (n = 1,708) (published between 2010 and 2024) were identified. Three RCTs were deemed to have a high risk of bias. All studies were considered trustworthy for inclusion in the meta-analysis according to the TRACT checklist. No significant difference was observed in live birth rates (risk ratio [RR]: 0.93, 95% confidence interval [CI]: 0.74-1.17; I<sup>2</sup> = 0%, 4 studies, n = 1,280; [sensitivity analysis: RR: 0.90, 95% CI: 0.32-2.52; I<sup>2</sup> = 0%, 2 studies, n = 1,060]), ongoing pregnancy rates (RR: 0.74, 95% CI: 0.37-1.51; I<sup>2</sup> = 1%, 3 studies, n = 536), and clinical pregnancy rates (RR: 0.86, 95% CI: 0.67-1.10; I<sup>2</sup> = 0%, 4 studies, n = 648). Similarly, no significant difference was observed in cycle cancellation rates and miscarriage rates. The sensitivity analysis, performed by excluding the three studies deemed to be at high risk of bias, did not materially alter the results obtained for all the aforementioned outcomes.</p><p><strong>Conclusion and relevance: </strong>Clinicians and patients should be informed that, on the basis of the best available evidence, frozen-thawed embryo transfer in mNC results in comparable live birth rates with NC, making it a pragmatic option for scheduling or convenience.</p><p><strong>Trial registration: </strong>The protocol for the systematic review was reg","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-14DOI: 10.1016/j.fertnstert.2026.02.018
J Preston Parry, Stephanie Estes, Ted L Anderson
{"title":"Rethinking do no harm.","authors":"J Preston Parry, Stephanie Estes, Ted L Anderson","doi":"10.1016/j.fertnstert.2026.02.018","DOIUrl":"10.1016/j.fertnstert.2026.02.018","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-11DOI: 10.1016/j.fertnstert.2026.01.035
David Boedeker, Michael J. Tucker, Kate Devine
{"title":"In ART, does the quarterback really need a left tackle?","authors":"David Boedeker, Michael J. Tucker, Kate Devine","doi":"10.1016/j.fertnstert.2026.01.035","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2026.01.035","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"118 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146152740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-11DOI: 10.1016/j.fertnstert.2026.02.004
Dongming Liu, Yaxing Guo, Ziyi Fan, Yang Wang
{"title":"An intraoperative localization method and a stepwise surgical technique for hysteroscopic treatment of International Federation of Gynecology and Obstetrics type 3 fibroid","authors":"Dongming Liu, Yaxing Guo, Ziyi Fan, Yang Wang","doi":"10.1016/j.fertnstert.2026.02.004","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2026.02.004","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"60 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146153311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}