首页 > 最新文献

Forensic science international最新文献

英文 中文
Surface preparation in serial number recovery: Its effect on accuracy and recovery times 序列号回收中的表面处理:对准确性和回收次数的影响
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-21 DOI: 10.1016/j.forsciint.2025.112741
J.R. Waszczuk , S. Bottrill , J. Raymond , C. Roux , S. Chadwick
A common recommendation when undertaking serial number restorations is to prepare the materials surface to a ‘mirror-like’ finish through various means including polishing. However, altered serial numbers are rarely defaced uniformly. Hence there are instances of forensic examiners not able to adequately level (polish) the materials surface without also potentially removing deformation detail that is needed to successfully restore the pre-defaced marking. To assess the importance of polishing in serial number restorations, 118 sample plates were stamped, obliterated, and then chemically etched. 59 plates were left with the coarse grinding marks from the obliteration process then restored, whilst the remaining 59 were treated with Brasso® polish and increasing grit from 120 to 1200 grit sandpaper, prior to restoration. Recovery times and accuracies of participant interpretations were recorded. The polished plates were found to take significantly less time to restore compared to the unpolished, but also appeared to provide no difference with the accuracy of interpretations. This study found that surface preparation (polishing) prior to serial number restoration (chemical etching) did not provide any increase in participant accuracy. This work further provided surface topographies of both polished and unpolished surfaces, which may be of assistance for practitioners undertaking laboratory based serial number restorations.
在进行序列号修复时,一个常见的建议是通过包括抛光在内的各种方法将材料表面准备成“镜面”。然而,更改的序列号很少被统一污损。因此,有些情况下,法医审查员无法充分平整(抛光)材料表面,同时也可能去除成功恢复预污损标记所需的变形细节。为了评估抛光在序列号修复中的重要性,对118个样品板进行了冲压、擦除,然后进行化学蚀刻。59块板留下了抹掉过程中留下的粗磨痕迹,然后进行修复,而其余59块板在修复之前使用Brasso®抛光并将砂纸的砂度从120增加到1200。记录参与者解释的恢复时间和准确性。研究发现,与未抛光的盘子相比,抛光的盘子恢复所需的时间要少得多,但在解释的准确性方面似乎也没有区别。本研究发现,序列号恢复(化学蚀刻)之前的表面处理(抛光)并没有提供任何参与者准确性的增加。这项工作进一步提供了抛光和未抛光表面的表面形貌,这可能有助于从业者进行基于实验室的序列号修复。
{"title":"Surface preparation in serial number recovery: Its effect on accuracy and recovery times","authors":"J.R. Waszczuk ,&nbsp;S. Bottrill ,&nbsp;J. Raymond ,&nbsp;C. Roux ,&nbsp;S. Chadwick","doi":"10.1016/j.forsciint.2025.112741","DOIUrl":"10.1016/j.forsciint.2025.112741","url":null,"abstract":"<div><div>A common recommendation when undertaking serial number restorations is to prepare the materials surface to a ‘mirror-like’ finish through various means including polishing. However, altered serial numbers are rarely defaced uniformly. Hence there are instances of forensic examiners not able to adequately level (polish) the materials surface without also potentially removing deformation detail that is needed to successfully restore the pre-defaced marking. To assess the importance of polishing in serial number restorations, 118 sample plates were stamped, obliterated, and then chemically etched. 59 plates were left with the coarse grinding marks from the obliteration process then restored, whilst the remaining 59 were treated with Brasso® polish and increasing grit from 120 to 1200 grit sandpaper, prior to restoration. Recovery times and accuracies of participant interpretations were recorded. The polished plates were found to take significantly less time to restore compared to the unpolished, but also appeared to provide no difference with the accuracy of interpretations. This study found that surface preparation (polishing) prior to serial number restoration (chemical etching) did not provide any increase in participant accuracy. This work further provided surface topographies of both polished and unpolished surfaces, which may be of assistance for practitioners undertaking laboratory based serial number restorations.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"379 ","pages":"Article 112741"},"PeriodicalIF":2.5,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Origin traceability of Amur tiger hair using stable isotope ratio mass spectrometry 用稳定同位素比值质谱法测定东北虎毛发的来源溯源
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-21 DOI: 10.1016/j.forsciint.2025.112736
Lin Feng , Chenjie Wei , Xianhe Deng , Yajun Li , Hongcheng Mei , Hongling Guo , Jiwei Qi , Xinghu Qin , Conghe Zhang , Jun Zhu , Can Hu
As an endangered species, the Amur tiger (Panthera tigris altaica) faces severe threats to its survival from illegal poaching and cross-border smuggling, which also undermines biodiversity. Traceability detection of Amur tigers is crucial for combating such crimes; however, current traceability efforts primarily rely on witness testimony, lacking scientific and technological support. To address this gap, this study pioneers the application of Isotope Ratio Mass Spectrometry (IRMS) in the field of forensic science, focusing on Amur tiger hair to develop a traceability technology. Hair samples were collected from 20 Amur tigers across 10 zoos in different regions of China, and their stable isotope abundance values were analyzed. The results showed no significant differences in δ¹³C, δ¹⁵N, δ²H, and δ¹⁸O values among different hair samples from the same individual. For different individuals in the same zoo, the isotope abundance values of their hair were dominated by the feeding conditions, with only minor variations. Additionally, the isotope abundance values of Amur tiger hair from different zoos exhibited characteristic distributions. The reasons for the differences were discussed, and the Amur tiger hairs from different zoos were differentiated. The stable isotope traceability technology for Amur tiger hair established in this study provides key technical support for combating illegal poaching and trade of Amur tigers in the forensic science field. It also offers a reference for the traceability detection of other endangered species.
作为濒危物种,东北虎(Panthera tigris altaica)的生存面临着非法偷猎和跨境走私的严重威胁,这也破坏了生物多样性。对东北虎的追踪检测对于打击此类犯罪至关重要;然而,目前的溯源工作主要依靠证人证词,缺乏科学技术支持。为了解决这一空白,本研究率先将同位素比质谱(IRMS)应用于法医学领域,重点研究东北虎毛发的可追溯性技术。研究人员采集了中国10个动物园20只东北虎的毛发样本,分析了它们的稳定同位素丰度值。结果显示,同一个体不同头发样本的δ¹³C、δ¹5 N、δ²H和δ¹⁸O值无显著差异。同一动物园不同个体毛发的同位素丰度值主要受饲养条件的影响,差异较小。此外,不同动物园东北虎毛发的同位素丰度值也呈现出特征分布。讨论了产生差异的原因,并对不同动物园的东北虎毛发进行了区分。本研究建立的东北虎毛发稳定同位素溯源技术,为法医学领域打击非法盗猎和贸易提供了关键技术支撑。为其他濒危物种的可追溯性检测提供参考。
{"title":"Origin traceability of Amur tiger hair using stable isotope ratio mass spectrometry","authors":"Lin Feng ,&nbsp;Chenjie Wei ,&nbsp;Xianhe Deng ,&nbsp;Yajun Li ,&nbsp;Hongcheng Mei ,&nbsp;Hongling Guo ,&nbsp;Jiwei Qi ,&nbsp;Xinghu Qin ,&nbsp;Conghe Zhang ,&nbsp;Jun Zhu ,&nbsp;Can Hu","doi":"10.1016/j.forsciint.2025.112736","DOIUrl":"10.1016/j.forsciint.2025.112736","url":null,"abstract":"<div><div>As an endangered species, the Amur tiger (<em>Panthera tigris altaica</em>) faces severe threats to its survival from illegal poaching and cross-border smuggling, which also undermines biodiversity. Traceability detection of Amur tigers is crucial for combating such crimes; however, current traceability efforts primarily rely on witness testimony, lacking scientific and technological support. To address this gap, this study pioneers the application of Isotope Ratio Mass Spectrometry (IRMS) in the field of forensic science, focusing on Amur tiger hair to develop a traceability technology. Hair samples were collected from 20 Amur tigers across 10 zoos in different regions of China, and their stable isotope abundance values were analyzed. The results showed no significant differences in <em>δ</em>¹³C, <em>δ</em>¹⁵N, <em>δ</em>²H, and <em>δ</em>¹⁸O values among different hair samples from the same individual. For different individuals in the same zoo, the isotope abundance values of their hair were dominated by the feeding conditions, with only minor variations. Additionally, the isotope abundance values of Amur tiger hair from different zoos exhibited characteristic distributions. The reasons for the differences were discussed, and the Amur tiger hairs from different zoos were differentiated. The stable isotope traceability technology for Amur tiger hair established in this study provides key technical support for combating illegal poaching and trade of Amur tigers in the forensic science field. It also offers a reference for the traceability detection of other endangered species.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"379 ","pages":"Article 112736"},"PeriodicalIF":2.5,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physicochemical changes to surface deposited decomposing bone over different timescales: Investigating the influence of bone fractures and the use of non-destructive analytical techniques 在不同时间尺度上沉积的分解骨表面的物理化学变化:研究骨折的影响和使用非破坏性分析技术
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-21 DOI: 10.1016/j.forsciint.2025.112743
C. Mein, J.R. Jones, C. Tennick, A. Williams
Considerations on the drivers of bone diagenesis have received a lot of attention, yet there is still more to understand, particularly in relation to chemical changes that can occur post-mortem, and the rate at which these occur. The physicochemical composition of bone is altered during the post-depositional period, leading to a more thermodynamically stable crystal lattice, thus increasing the long-term survivability of the bone. Research has shown the potential for soft tissue trauma to affect the decomposition process, but the effect of bone trauma and fractures on diagenesis has not yet been considered. Most bone diagenesis research uses destructive analytical techniques, resulting in the loss of samples and the inability to perform repeat analyses. Presented here is a study investigating changes in the physicochemical composition of disarticulated Sus scrofa ribs, with and without fractures, using non-destructive analytical techniques. The aim was to explore the timescales in which physicochemical changes occur and to investigate the potential influence of bone fractures. Intact (control) or fractured (blunt-force or sharp-force) bone samples were deposited on a grassy surface for up to 240 days. Physicochemical changes to the bone sections were analysed using scanning electron microscopy – energy dispersive spectroscopy and Fourier transform infrared spectroscopy with attenuated total reflectance. It was hypothesised that physicochemical changes could be quantified in < 240 days using these techniques, and that the presence of fractures would affect the observed changes. Statistically significant (p < 0.05) losses in Na, K, and Mg and increases in crystallinity were seen over time, as well as significant changes in carbonate content and a significant loss of proteins. Differences physicochemical composition were observed between the undamaged and fractured samples, and the samples with BFT appeared to be the least affected for many elemental and IR parameters indicating BFT could potentially inhibit physicochemical change. The analysis of Na and K showed potential for PMI estimation, as these changed significantly over time, but as these were influenced by the presence of bone fractures, more research is needed fully understand how different variables can affect physicochemical change in bone, particularly the presence of bone fractures/damage.
关于骨成岩的驱动因素的考虑已经受到了很多关注,但仍有更多的东西需要理解,特别是与死后可能发生的化学变化有关,以及这些变化发生的速度。在沉积后的时期,骨的物理化学成分发生了改变,导致了一个更热力学稳定的晶格,从而增加了骨的长期存活能力。研究表明,软组织创伤可能影响分解过程,但骨创伤和骨折对成岩作用的影响尚未得到考虑。大多数骨成岩研究使用破坏性分析技术,导致样品丢失和无法进行重复分析。本文介绍了一项研究,利用非破坏性分析技术,研究了有和没有骨折的断节Sus scrofa肋骨的物理化学成分的变化。目的是探索物理化学变化发生的时间尺度,并调查骨折的潜在影响。完整(对照)或骨折(钝力或利器)的骨样本在草地表面沉积长达240天。利用扫描电子显微镜-能量色散光谱和衰减全反射傅里叶变换红外光谱分析了骨切片的物理化学变化。假设使用这些技术可以在<; 240天内量化物理化学变化,并且裂缝的存在会影响观察到的变化。随着时间的推移,Na、K和Mg的损失和结晶度的增加在统计学上具有显著意义(p <; 0.05),碳酸盐含量也发生了显著变化,蛋白质的损失也显著。在未损伤和破裂样品之间观察到物理化学成分的差异,并且BFT样品对许多元素和IR参数的影响最小,表明BFT可能抑制物理化学变化。Na和K的分析显示了PMI估计的潜力,因为它们随着时间的推移而显著变化,但由于它们受到骨折存在的影响,因此需要更多的研究来充分了解不同变量如何影响骨的物理化学变化,特别是骨折/损伤的存在。
{"title":"Physicochemical changes to surface deposited decomposing bone over different timescales: Investigating the influence of bone fractures and the use of non-destructive analytical techniques","authors":"C. Mein,&nbsp;J.R. Jones,&nbsp;C. Tennick,&nbsp;A. Williams","doi":"10.1016/j.forsciint.2025.112743","DOIUrl":"10.1016/j.forsciint.2025.112743","url":null,"abstract":"<div><div>Considerations on the drivers of bone diagenesis have received a lot of attention, yet there is still more to understand, particularly in relation to chemical changes that can occur post-mortem, and the rate at which these occur. The physicochemical composition of bone is altered during the post-depositional period, leading to a more thermodynamically stable crystal lattice, thus increasing the long-term survivability of the bone. Research has shown the potential for soft tissue trauma to affect the decomposition process, but the effect of bone trauma and fractures on diagenesis has not yet been considered. Most bone diagenesis research uses destructive analytical techniques, resulting in the loss of samples and the inability to perform repeat analyses. Presented here is a study investigating changes in the physicochemical composition of disarticulated <em>Sus scrofa</em> ribs, with and without fractures, using non-destructive analytical techniques. The aim was to explore the timescales in which physicochemical changes occur and to investigate the potential influence of bone fractures. Intact (control) or fractured (blunt-force or sharp-force) bone samples were deposited on a grassy surface for up to 240 days. Physicochemical changes to the bone sections were analysed using scanning electron microscopy – energy dispersive spectroscopy and Fourier transform infrared spectroscopy with attenuated total reflectance. It was hypothesised that physicochemical changes could be quantified in &lt; 240 days using these techniques, and that the presence of fractures would affect the observed changes. Statistically significant (<em>p</em> &lt; 0.05) losses in Na, K, and Mg and increases in crystallinity were seen over time, as well as significant changes in carbonate content and a significant loss of proteins. Differences physicochemical composition were observed between the undamaged and fractured samples, and the samples with BFT appeared to be the least affected for many elemental and IR parameters indicating BFT could potentially inhibit physicochemical change. The analysis of Na and K showed potential for PMI estimation, as these changed significantly over time, but as these were influenced by the presence of bone fractures, more research is needed fully understand how different variables can affect physicochemical change in bone, particularly the presence of bone fractures/damage.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"379 ","pages":"Article 112743"},"PeriodicalIF":2.5,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of firearm toolmarks identification: Progress, challenges, and perspectives 枪支工具标记识别综述:进展、挑战和前景。
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-20 DOI: 10.1016/j.forsciint.2025.112735
Yiran Xin, Yunqi Tang, Yaping Luo, Kang Wang
Firearm toolmarks identification has evolved through two major technological paradigms. During the traditional morphology-based phase, investigators relied on two-dimensional microscopic imaging together with the Consecutive Matching Striae method. This approach entailed manually comparing the striated and impressed microscopic marks on bullets and cartridge cases to attribute them to a specific firearm. However, its inherent subjectivity and the lack of statistical quantification drew judicial scrutiny. Recent breakthroughs in three-dimensional microscopic imaging—specifically confocal microscopy, scanning electron microscopy, and micro-computed tomography—have prompted a paradigm shift toward probabilistic assessment frameworks grounded in likelihood ratios. This involves extracting 3D topographical features from firearm marks using deep learning and the Congruent Matching Cells method. By constructing probabilistic models under the hypotheses of "same-source" and "different-source" origin using Bayesian statistics, this approach transforms identification conclusions into quantifiable LR values, significantly enhancing objectivity and credibility in court. Current research focuses on developing automated identification systems and improving algorithm interpretability to meet the transparency demands of legal settings. Future directions must address challenges like multimodal data fusion and the identification of non-standardized firearms (e.g., homemade, improvised, or additive manufactured weapons). By integrating 3D topography, material composition, and dynamic behavior data, this aims to solve the attribution difficulties posed by novel criminal tools like 3D-printed weapons, thereby driving the field toward intelligent and standardized development. This paper systematically analyzes the logical progression of this two-phase technological evolution, providing a theoretical foundation for building a verifiable, high-reliability firearm identification system.
枪支工具标记的识别已经通过两种主要的技术范式发展。在传统的基于形态学的阶段,研究人员依赖于二维显微成像和连续匹配条纹方法。这种方法需要手动比较子弹和弹壳上的条纹和刻痕显微标记,以确定它们属于特定的枪支。然而,其固有的主观性和缺乏统计量化引起了司法审查。最近在三维显微成像方面的突破——特别是共聚焦显微镜、扫描电子显微镜和微计算机断层扫描——促使了一种范式的转变,即以似然比为基础的概率评估框架。这包括使用深度学习和一致匹配单元方法从枪支痕迹中提取3D地形特征。该方法利用贝叶斯统计构建“同源”和“异源”起源假设下的概率模型,将鉴定结论转化为可量化的LR值,显著提高了法庭的客观性和可信度。目前的研究重点是开发自动识别系统和提高算法的可解释性,以满足法律设置的透明度要求。未来的方向必须解决诸如多模态数据融合和识别非标准化枪支(如自制、简易或增材制造武器)等挑战。通过整合3D地形、材料成分和动态行为数据,解决3D打印武器等新型犯罪工具带来的归因难题,推动该领域向智能化、规范化方向发展。本文系统分析了这两阶段技术演进的逻辑进程,为构建可验证、高可靠性的枪支识别系统提供了理论基础。
{"title":"A review of firearm toolmarks identification: Progress, challenges, and perspectives","authors":"Yiran Xin,&nbsp;Yunqi Tang,&nbsp;Yaping Luo,&nbsp;Kang Wang","doi":"10.1016/j.forsciint.2025.112735","DOIUrl":"10.1016/j.forsciint.2025.112735","url":null,"abstract":"<div><div>Firearm toolmarks identification has evolved through two major technological paradigms. During the traditional morphology-based phase, investigators relied on two-dimensional microscopic imaging together with the Consecutive Matching Striae method. This approach entailed manually comparing the striated and impressed microscopic marks on bullets and cartridge cases to attribute them to a specific firearm. However, its inherent subjectivity and the lack of statistical quantification drew judicial scrutiny. Recent breakthroughs in three-dimensional microscopic imaging—specifically confocal microscopy, scanning electron microscopy, and micro-computed tomography—have prompted a paradigm shift toward probabilistic assessment frameworks grounded in likelihood ratios. This involves extracting 3D topographical features from firearm marks using deep learning and the Congruent Matching Cells method. By constructing probabilistic models under the hypotheses of \"same-source\" and \"different-source\" origin using Bayesian statistics, this approach transforms identification conclusions into quantifiable LR values, significantly enhancing objectivity and credibility in court. Current research focuses on developing automated identification systems and improving algorithm interpretability to meet the transparency demands of legal settings. Future directions must address challenges like multimodal data fusion and the identification of non-standardized firearms (e.g., homemade, improvised, or additive manufactured weapons). By integrating 3D topography, material composition, and dynamic behavior data, this aims to solve the attribution difficulties posed by novel criminal tools like 3D-printed weapons, thereby driving the field toward intelligent and standardized development. This paper systematically analyzes the logical progression of this two-phase technological evolution, providing a theoretical foundation for building a verifiable, high-reliability firearm identification system.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"379 ","pages":"Article 112735"},"PeriodicalIF":2.5,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145603363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Petechiae in non-fatal strangulation: Prevalence, predictors and time-dependent detectability in forensic assessment 非致命勒死中的瘀点:在法医评估中的患病率、预测因素和随时间变化的可检出性。
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-19 DOI: 10.1016/j.forsciint.2025.112730
Julia Babigian , Luca Berti , Lars Oesterhelweg , Alberto Amadasi
Petechiae are a key yet inconsistently observed finding following non-fatal strangulation, and their detection is influenced by both anatomical location and time since the event. This variability complicates forensic evaluation. This retrospective cohort study analysed 541 adult cases assessed at the Violence Protection Ambulatory of Charité Berlin between 2017 and 2023. The presence of petechiae was evaluated according to location and time interval to examination. Associations with clinical symptoms and external signs were examined using logistic regression, generalised estimating equations, and receiver operating characteristic (ROC) analysis. Petechiae were observed in 10 % of cases (54/541) and were significantly associated with shorter intervals between the event and examination (mean: 26 h vs. 61 h, p < 0.001), with a cut-off of 41.5 h (AUC 0.73 (95 % CI 0.6739–0.7953)). Early detectability was most common in the conjunctiva, while petechiae in the posterior ear region persisted longer (OR = 27.65). Clinical symptoms such as dyspnoea, hoarseness, and dysphagia were also associated with the presence of petechiae. A two-item risk score combining dyspnoea and absence of external skin findings achieved an AUC of 0.72. These findings suggest that petechiae are both time- and site-dependent and that clinical symptoms and external signs may support early identification. The proposed score provides a practical tool to aid forensic assessment in cases of suspected strangulation.
瘀点是在非致命勒死后观察到的关键但不一致的发现,它们的检测受到解剖位置和事件发生后的时间的影响。这种可变性使法医鉴定复杂化。这项回顾性队列研究分析了2017年至2023年在柏林慈善机构暴力保护门诊评估的541例成人病例。根据检查的位置和时间间隔来评估斑点的存在。使用逻辑回归、广义估计方程和受试者工作特征(ROC)分析来检验与临床症状和外部体征的关联。10 %的病例(54/541)观察到瘀点,并且与事件和检查之间的较短间隔显著相关(平均:26 h对61 h, p
{"title":"Petechiae in non-fatal strangulation: Prevalence, predictors and time-dependent detectability in forensic assessment","authors":"Julia Babigian ,&nbsp;Luca Berti ,&nbsp;Lars Oesterhelweg ,&nbsp;Alberto Amadasi","doi":"10.1016/j.forsciint.2025.112730","DOIUrl":"10.1016/j.forsciint.2025.112730","url":null,"abstract":"<div><div>Petechiae are a key yet inconsistently observed finding following non-fatal strangulation, and their detection is influenced by both anatomical location and time since the event. This variability complicates forensic evaluation. This retrospective cohort study analysed 541 adult cases assessed at the Violence Protection Ambulatory of Charité Berlin between 2017 and 2023. The presence of petechiae was evaluated according to location and time interval to examination. Associations with clinical symptoms and external signs were examined using logistic regression, generalised estimating equations, and receiver operating characteristic (ROC) analysis. Petechiae were observed in 10 % of cases (54/541) and were significantly associated with shorter intervals between the event and examination (mean: 26 h vs. 61 h, p &lt; 0.001), with a cut-off of 41.5 h (AUC 0.73 (95 % CI 0.6739–0.7953)). Early detectability was most common in the conjunctiva, while petechiae in the posterior ear region persisted longer (OR = 27.65). Clinical symptoms such as dyspnoea, hoarseness, and dysphagia were also associated with the presence of petechiae. A two-item risk score combining dyspnoea and absence of external skin findings achieved an AUC of 0.72. These findings suggest that petechiae are both time- and site-dependent and that clinical symptoms and external signs may support early identification. The proposed score provides a practical tool to aid forensic assessment in cases of suspected strangulation.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112730"},"PeriodicalIF":2.5,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145573381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implication of GHB in proactive drug facilitated crime in Paris, France GHB在法国巴黎主动毒品促进犯罪中的意义。
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-18 DOI: 10.1016/j.forsciint.2025.112734
Léo Dubois , Romain Magny , Laurence Labat , Clément Augustin , Tiffany Pinto , Jennifer Truchot , Marc Liautard , Pascal Houzé , Laurène Dufayet

Objective

To assess the proportion of suspected pro-active drug facilitated crime (DFC) cases involving GHB through an appropriate toxicological assessment for any adult presenting as a victim of proactive DFC within 10 h at the Department of Forensic Medicine (DFM) of Hôtel-Dieu hospital or the emergency departments of Hôtel-Dieu and Cochin hospitals, Paris, France.

Methodology

Adults presenting at the DFM of Hôtel-Dieu hospital or the emergency departments of Hôtel-Dieu and Cochin for suspected proactive DFC were included. Blood and urine samples were sent to the toxicology laboratory of Lariboisière for a toxicological assessment, including GHB measurement and screening using high-performance liquid chromatography coupled with high-resolution mass spectrometry (LC-ESI-HRMS/MS). Cannabinoid’s plasma concentration and urine confirmation were performed using LC-ESI-HRMS/MS. Other compounds were quantified by liquid chromatography-tandem mass spectrometry. This study was approved by the AP-HP Centre Research Ethics Committee, registered under IRB #00011928, and listed in the AP-HP general treatment registry

Results

A total of 49 individuals were included in the study. The mean sampling time was 6.0 h. The sex ratio was 0.33, and the median age was 24.11 years. Voluntary consumption of psychoactive substances in the hours before the event were frequently reported by the patients (91.8 % for ethanol, 20.4 % for illicit substances and 12.2 % for medication with potential psychoactive effects). Six patients tested positive for GHB in urine (mean: 576.3 mg/L), and three were also positive in blood (mean: 46 mg/L). Among them, none reported voluntary GHB consumption. Additionally, undeclared PAS were detected in five other patients, including benzodiazepines and non-therapeutic PAS, suggesting cases of proactive DFC. Overall, proactive DFC was probable in 11 cases and opportunistic DFC in 17 cases.

Conclusion

Our results show a significant proportion of probable GHB-related proactive DFC cases, often within a chemsex context. Further studies, in collaboration with emergency services are necessary to better understand this rising phenomenon and GHB might be under detected in DFC cases due to its pharmacokinetic properties.
目的:通过对法国巴黎Hôtel-Dieu医院法医学部(DFM)或Hôtel-Dieu和Cochin医院急诊科在10 小时内出现的主动药物促进犯罪(DFC)受害者的成人进行适当的毒理学评估,评估涉及GHB的疑似主动药物促进犯罪(DFC)案件的比例。方法:纳入在Hôtel-Dieu医院DFM或Hôtel-Dieu和Cochin的急诊科就诊的疑似主动性DFC的成年人。血液和尿液样本被送到lariboisi毒理学实验室进行毒理学评估,包括使用高效液相色谱和高分辨率质谱(LC-ESI-HRMS/MS)进行GHB测量和筛选。采用LC-ESI-HRMS/MS对大麻素血药浓度和尿液进行确证。其他化合物采用液相色谱-串联质谱法定量。本研究已获AP-HP中心研究伦理委员会批准,注册编号为IRB #00011928,并列入AP-HP一般治疗注册表。结果:共有49名受试者纳入本研究。平均采样时间为6.0 h。性别比为0.33,中位年龄为24.11岁。患者经常报告在事件发生前数小时内自愿使用精神活性物质(酒精91.8% %,非法物质20.4% %,具有潜在精神作用的药物12.2 %)。6名患者尿液中GHB检测呈阳性(平均:576.3 mg/L), 3名患者血液中GHB检测呈阳性(平均:46 mg/L)。其中,没有人报告自愿使用GHB。此外,在其他5例患者中检测到未申报的PAS,包括苯二氮卓类药物和非治疗性PAS,提示主动性DFC病例。总体而言,11例为主动DFC, 17例为机会性DFC。结论:我们的结果显示了很大一部分可能与ghb相关的前瞻性DFC病例,通常在化学性背景下。需要与急救部门合作开展进一步研究,以更好地了解这一日益增加的现象,并且由于其药代动力学特性,在DFC病例中可能无法检测到GHB。
{"title":"Implication of GHB in proactive drug facilitated crime in Paris, France","authors":"Léo Dubois ,&nbsp;Romain Magny ,&nbsp;Laurence Labat ,&nbsp;Clément Augustin ,&nbsp;Tiffany Pinto ,&nbsp;Jennifer Truchot ,&nbsp;Marc Liautard ,&nbsp;Pascal Houzé ,&nbsp;Laurène Dufayet","doi":"10.1016/j.forsciint.2025.112734","DOIUrl":"10.1016/j.forsciint.2025.112734","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the proportion of suspected pro-active drug facilitated crime (DFC) cases involving GHB through an appropriate toxicological assessment for any adult presenting as a victim of proactive DFC within 10 h at the Department of Forensic Medicine (DFM) of Hôtel-Dieu hospital or the emergency departments of Hôtel-Dieu and Cochin hospitals, Paris, France.</div></div><div><h3>Methodology</h3><div>Adults presenting at the DFM of Hôtel-Dieu hospital or the emergency departments of Hôtel-Dieu and Cochin for suspected proactive DFC were included. Blood and urine samples were sent to the toxicology laboratory of Lariboisière for a toxicological assessment, including GHB measurement and screening using high-performance liquid chromatography coupled with high-resolution mass spectrometry (LC-ESI-HRMS/MS). Cannabinoid’s plasma concentration and urine confirmation were performed using LC-ESI-HRMS/MS. Other compounds were quantified by liquid chromatography-tandem mass spectrometry. This study was approved by the AP-HP Centre Research Ethics Committee, registered under IRB #00011928, and listed in the AP-HP general treatment registry</div></div><div><h3>Results</h3><div>A total of 49 individuals were included in the study. The mean sampling time was 6.0 h. The sex ratio was 0.33, and the median age was 24.11 years. Voluntary consumption of psychoactive substances in the hours before the event were frequently reported by the patients (91.8 % for ethanol, 20.4 % for illicit substances and 12.2 % for medication with potential psychoactive effects). Six patients tested positive for GHB in urine (mean: 576.3 mg/L), and three were also positive in blood (mean: 46 mg/L). Among them, none reported voluntary GHB consumption. Additionally, undeclared PAS were detected in five other patients, including benzodiazepines and non-therapeutic PAS, suggesting cases of proactive DFC. Overall, proactive DFC was probable in 11 cases and opportunistic DFC in 17 cases.</div></div><div><h3>Conclusion</h3><div>Our results show a significant proportion of probable GHB-related proactive DFC cases, often within a chemsex context. Further studies, in collaboration with emergency services are necessary to better understand this rising phenomenon and GHB might be under detected in DFC cases due to its pharmacokinetic properties.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112734"},"PeriodicalIF":2.5,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145573369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mechanisms of forensic vacuum metal deposition (fVMD): A literature review 法医真空金属沉积(fVMD)机制的文献综述。
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-18 DOI: 10.1016/j.forsciint.2025.112733
Aaron Dove , Benoit Daoust , Andreas Ruëdiger
Since the early 1970s, forensic vacuum metal deposition (fVMD) has been used in operational casework. It is renowned for its sensitivity and ability to work on aged impressions and difficult substrates. However, the precise mechanism by which this development occurs remains unclear. This article examines the current literature on fVMD to see what is known about the technique, what is unclear, and what are the next steps that should be taken. This review shows that, while the operational utility of the technique is not in question, none of the currently posited theories can explain all the observed phenomena. They are therefore, at best, incomplete, and further research is required.
自20世纪70年代初以来,法医真空金属沉积(fVMD)已用于实际案件工作。它以其敏感性和能力而闻名,可以在老化的印痕和困难的基材上工作。然而,这种发展发生的确切机制尚不清楚。本文研究了当前关于fVMD的文献,以了解关于该技术的已知内容,不清楚的内容以及应该采取的下一步措施。这篇综述表明,虽然该技术的操作效用没有问题,但目前假设的理论都不能解释所有观察到的现象。因此,它们充其量是不完整的,需要进一步的研究。
{"title":"The mechanisms of forensic vacuum metal deposition (fVMD): A literature review","authors":"Aaron Dove ,&nbsp;Benoit Daoust ,&nbsp;Andreas Ruëdiger","doi":"10.1016/j.forsciint.2025.112733","DOIUrl":"10.1016/j.forsciint.2025.112733","url":null,"abstract":"<div><div>Since the early 1970s, forensic vacuum metal deposition (fVMD) has been used in operational casework. It is renowned for its sensitivity and ability to work on aged impressions and difficult substrates. However, the precise mechanism by which this development occurs remains unclear. This article examines the current literature on fVMD to see what is known about the technique, what is unclear, and what are the next steps that should be taken. This review shows that, while the operational utility of the technique is not in question, none of the currently posited theories can explain all the observed phenomena. They are therefore, at best, incomplete, and further research is required.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112733"},"PeriodicalIF":2.5,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145563455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons from the “Trial of the Century” and early forensic science efforts: Beginnings of U.S. forensic science and the little-known role of the National Bureau of Standards 从“世纪审判”和早期法医学努力中吸取的教训:美国法医学的开端和国家标准局鲜为人知的作用。
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-17 DOI: 10.1016/j.forsciint.2025.112732
John M. Butler
This article briefly discusses early pioneers in Europe and the United States involved in forensic science (also known then as criminalistics or police science), as well as a 1929 European tour by Calvin Goddard that would link efforts and raise awareness of activities on both sides of the Atlantic Ocean. High profile crimes often propel disciplines in forensic science to make significant progress. The first so-called “Crime of the Century” involved kidnapping the 20-month-old son of famous aviator Charles Lindbergh from his second-story nursery on the evening of March 1, 1932. This set in motion a large investigation that would lead to the “Trial of the Century” almost three years later. Forensic science evidence in the form of handwriting comparisons with 15 ransom notes and analysis of a ladder left at the crime scene would play key roles in the conviction of Bruno Richard Hauptmann. Widespread media attention and publicly available records, some which have only recently come to light, provide opportunities to consider how this investigation and trial contributed to the development and foundations of early forensic science in the United States. Lessons from the study of early forensic science efforts can benefit this field today. In particular, the little-known roles of the National Bureau of Standards (NBS) and a physicist named Wilmer Souder in the Lindbergh baby kidnapping case. Today, almost a century later, NBS, now known as the National Institute of Standards and Technology (NIST), continues to make important advances in forensic science research, standards, and scientific foundation studies.
本文简要讨论了欧洲和美国早期从事法医学(当时也被称为犯罪学或警务学)的先驱,以及1929年加尔文·戈达德(Calvin Goddard)的欧洲之旅,这次旅行将把大西洋两岸的努力联系起来,提高了人们对法医学活动的认识。重大犯罪往往推动法医学学科取得重大进展。第一起所谓的“世纪犯罪”是1932年3月1日晚上,著名飞行员查尔斯·林德伯格在二楼的托儿所绑架了他20个月大的儿子。这引发了一场大规模的调查,这场调查将导致近三年后的“世纪审判”。对15张勒索信的笔迹比对以及对犯罪现场留下的梯子的分析等法医学证据将在布鲁诺·理查德·豪普特曼的定罪中发挥关键作用。广泛的媒体关注和公开的记录,其中一些是最近才曝光的,提供了机会来考虑这次调查和审判是如何为美国早期法医学的发展和基础做出贡献的。早期法医学研究的经验教训对今天的这一领域有益。尤其是美国国家标准局(NBS)和物理学家威尔默·苏德(Wilmer Souder)在林德伯格婴儿绑架案中鲜为人知的角色。近一个世纪后的今天,NBS,即现在的国家标准与技术研究院(NIST),继续在法医学研究、标准和科学基础研究方面取得重要进展。
{"title":"Lessons from the “Trial of the Century” and early forensic science efforts: Beginnings of U.S. forensic science and the little-known role of the National Bureau of Standards","authors":"John M. Butler","doi":"10.1016/j.forsciint.2025.112732","DOIUrl":"10.1016/j.forsciint.2025.112732","url":null,"abstract":"<div><div>This article briefly discusses early pioneers in Europe and the United States involved in forensic science (also known then as criminalistics or police science), as well as a 1929 European tour by Calvin Goddard that would link efforts and raise awareness of activities on both sides of the Atlantic Ocean. High profile crimes often propel disciplines in forensic science to make significant progress. The first so-called “Crime of the Century” involved kidnapping the 20-month-old son of famous aviator Charles Lindbergh from his second-story nursery on the evening of March 1, 1932. This set in motion a large investigation that would lead to the “Trial of the Century” almost three years later. Forensic science evidence in the form of handwriting comparisons with 15 ransom notes and analysis of a ladder left at the crime scene would play key roles in the conviction of Bruno Richard Hauptmann. Widespread media attention and publicly available records, some which have only recently come to light, provide opportunities to consider how this investigation and trial contributed to the development and foundations of early forensic science in the United States. Lessons from the study of early forensic science efforts can benefit this field today. In particular, the little-known roles of the National Bureau of Standards (NBS) and a physicist named Wilmer Souder in the Lindbergh baby kidnapping case. Today, almost a century later, NBS, now known as the National Institute of Standards and Technology (NIST), continues to make important advances in forensic science research, standards, and scientific foundation studies.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112732"},"PeriodicalIF":2.5,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145563474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sudden unexpected death in infancy (SUDI) and myocarditis: State of the art and medico-legal implications. A systematic review 婴儿猝死(SUDI)和心肌炎:最新进展和医学法律意义。系统回顾
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-16 DOI: 10.1016/j.forsciint.2025.112731
Elena Giovannini , Maria Paola Bonasoni , Simone Santelli , Ester Maria Cavalli , Giovanni Dal Lago , Susi Pelotti , Paolo Fais
Sudden infant deaths should be recognized as a public health concern, and understanding their underlying causes is crucial to elucidate this still poorly understood phenomenon. Despite efforts and standardized diagnostic protocols including autopsies and laboratory tests, the causes of sudden infant death often remain unclear in the 75 % of the cases. The aim of this review is to analyze the available data on SUDI associated with myocarditis, offering forensic pathologists a comprehensive overview of this topic, with a particular focus not only on pathophysiological and clinical implications but also on medico-legal aspects. This systematic review included articles concerning SUDI related to myocarditis, in particular etiopathogenesis, diagnosis, consequences and medico-legal implications. The research was carried out on articles written in English published between January 1990 and December 2024. A total of 557 studies were found through the electronic search and 11 studies were included after cross-referenced research on the references of the examined full-text articles. A total of 31 studies were included in this systematic review. The study showed that a definitive diagnosis of myocarditis should only be established when all necessary criteria have been met, given the potential liability implications of asserting a specific cause of death in an infant condition that remains the subject of ongoing debate and research. To optimize this process, the inclusion of expert pediatric pathologists in multidisciplinary teams is strongly recommended to standardize analytical methods and guide autopsy, histological, and genetic examinations based on the unique characteristics of the pediatric population.
婴儿猝死应被视为一个公共卫生问题,了解其潜在原因对于阐明这一仍知之甚少的现象至关重要。尽管努力和标准化的诊断方案,包括尸检和实验室检查,在75% %的病例中,婴儿猝死的原因仍然不清楚。本综述的目的是分析与心肌炎相关的SUDI的现有数据,为法医病理学家提供这一主题的全面概述,特别关注的不仅是病理生理和临床意义,还有医学法律方面。本系统综述纳入了与心肌炎相关的SUDI,特别是其发病机制、诊断、后果和法医学意义。这项研究是对1990年1月至2024年12月期间发表的英文文章进行的。通过电子检索共检索到557项研究,通过对被检查全文文章的参考文献进行交叉参考研究,纳入了11项研究。本系统综述共纳入31项研究。该研究表明,只有在满足所有必要标准的情况下,才能确定心肌炎的明确诊断,因为在婴儿情况下断言特定的死亡原因可能涉及责任问题,这仍然是正在进行辩论和研究的主题。为了优化这一过程,强烈建议将儿科病理学专家纳入多学科团队,以标准化分析方法,并根据儿科人群的独特特征指导尸检、组织学和遗传检查。
{"title":"Sudden unexpected death in infancy (SUDI) and myocarditis: State of the art and medico-legal implications. A systematic review","authors":"Elena Giovannini ,&nbsp;Maria Paola Bonasoni ,&nbsp;Simone Santelli ,&nbsp;Ester Maria Cavalli ,&nbsp;Giovanni Dal Lago ,&nbsp;Susi Pelotti ,&nbsp;Paolo Fais","doi":"10.1016/j.forsciint.2025.112731","DOIUrl":"10.1016/j.forsciint.2025.112731","url":null,"abstract":"<div><div>Sudden infant deaths should be recognized as a public health concern, and understanding their underlying causes is crucial to elucidate this still poorly understood phenomenon. Despite efforts and standardized diagnostic protocols including autopsies and laboratory tests, the causes of sudden infant death often remain unclear in the 75 % of the cases. The aim of this review is to analyze the available data on SUDI associated with myocarditis, offering forensic pathologists a comprehensive overview of this topic, with a particular focus not only on pathophysiological and clinical implications but also on medico-legal aspects. This systematic review included articles concerning SUDI related to myocarditis, in particular etiopathogenesis, diagnosis, consequences and medico-legal implications. The research was carried out on articles written in English published between January 1990 and December 2024. A total of 557 studies were found through the electronic search and 11 studies were included after cross-referenced research on the references of the examined full-text articles. A total of 31 studies were included in this systematic review. The study showed that a definitive diagnosis of myocarditis should only be established when all necessary criteria have been met, given the potential liability implications of asserting a specific cause of death in an infant condition that remains the subject of ongoing debate and research. To optimize this process, the inclusion of expert pediatric pathologists in multidisciplinary teams is strongly recommended to standardize analytical methods and guide autopsy, histological, and genetic examinations based on the unique characteristics of the pediatric population.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112731"},"PeriodicalIF":2.5,"publicationDate":"2025-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145576242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluative sub-source and activity level reporting in Austria, Germany and Switzerland 在奥地利,德国和瑞士评估子源和活动水平报告。
IF 2.5 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2025-11-15 DOI: 10.1016/j.forsciint.2025.112729
Aileen Sorg , Katja Anslinger , Petra Böhme , Lisa Dierig , Miriam Ender , Melanie Grabmüller , Galina Kulstein , Manuel Pfeifer , Ulrike Schmidt , Iris Schulz , Maria Seidel , Christina Stein , Richard Zehner , Martin Zieger
An increasing number of scientific studies in the field of forensic genetics suggest that questions arising in courtrooms have shifted in recent years from "Whose DNA is it?" to "How did that person's DNA get there?", or, expressed in the terminology of the field, from questions at the sub-source level to questions at the activity level. The increasing number of studies on TPPR (transfer, persistence, prevalence, recovery) of DNA are of great help to answer such questions at the activity level. However, to date, little information is available about the actual numbers of cases in which activity level assessments were of relevance for the court. It must be considered an open question whether this increasing interest in activity level reporting (ALR) in the scientific community is based on an actual increase of requests for reporting in casework, or whether it is currently rather driven by a greater awareness for the complexity of DNA reporting in the academic arena itself. To assess this question for a part of Central Europe, we conducted an online survey in fourteen institutes in the German-speaking region of Switzerland, in Austria and in Germany over three months in spring 2024. Although the participants believe that ALR is useful for the evaluation of DNA evidence, they also report having limited knowledge therein and that it is in fact rarely requested in practice. No significant increase in ALR reporting was noted by the participants we surveyed over the last ten years. In addition to the development of ALR reporting, we also assessed evaluative sub-source level reporting (ESSLR) to monitor the potential effect of the advent of probabilistic genotyping on numbers of likelihood ratio (LR) calculations. It appears that most participating institutions still use binary/semi-continuous calculation software rather than fully continuous models. There has been no significant increase or decrease in LR calculations for single/major profiles, nor for DNA mixtures. The absence of ALR requests together with a constant number of ESSLR calculations thereby strongly suggests that the perceived shift from (sub-)sub-source level reporting to activity level reporting did not (yet) happen in German-speaking countries.
法医遗传学领域越来越多的科学研究表明,近年来法庭上出现的问题已经从“这是谁的DNA ?”转变为“那个人的DNA是如何到达那里的?”,或者,用该领域的术语来说,从子来源层面的问题转变为活动层面的问题。越来越多的DNA TPPR(转移、持续、流行、恢复)研究有助于在活性水平上回答这些问题。但是,迄今为止,关于活动水平评估与法院有关的案件的实际数目的资料很少。科学界对活动水平报告(ALR)日益增长的兴趣是基于案例工作中报告要求的实际增加,还是目前由学术领域本身对DNA报告复杂性的更大认识所驱动,这必须被视为一个悬而未决的问题。为了评估中欧部分地区的这个问题,我们在瑞士德语区、奥地利和德国的14个研究所进行了一项在线调查,调查时间为2024年春季的三个月。虽然参与者认为ALR对DNA证据的评估是有用的,但他们也报告说他们在这方面的知识有限,实际上在实践中很少要求。在过去十年中,我们调查的参与者没有注意到ALR报告的显著增加。除了发展ALR报告外,我们还评估了评估性子源水平报告(ESSLR),以监测概率基因分型的出现对似然比(LR)计算数量的潜在影响。似乎大多数参与机构仍然使用二进制/半连续计算软件,而不是全连续模型。对于单一/主要谱,以及DNA混合物,LR计算没有显著的增加或减少。因此,缺乏ALR请求以及固定数量的ESSLR计算强烈表明,在德语国家,从(次)子源级报告到活动级报告的感知转变(尚未)发生。
{"title":"Evaluative sub-source and activity level reporting in Austria, Germany and Switzerland","authors":"Aileen Sorg ,&nbsp;Katja Anslinger ,&nbsp;Petra Böhme ,&nbsp;Lisa Dierig ,&nbsp;Miriam Ender ,&nbsp;Melanie Grabmüller ,&nbsp;Galina Kulstein ,&nbsp;Manuel Pfeifer ,&nbsp;Ulrike Schmidt ,&nbsp;Iris Schulz ,&nbsp;Maria Seidel ,&nbsp;Christina Stein ,&nbsp;Richard Zehner ,&nbsp;Martin Zieger","doi":"10.1016/j.forsciint.2025.112729","DOIUrl":"10.1016/j.forsciint.2025.112729","url":null,"abstract":"<div><div>An increasing number of scientific studies in the field of forensic genetics suggest that questions arising in courtrooms have shifted in recent years from \"Whose DNA is it?\" to \"How did that person's DNA get there?\", or, expressed in the terminology of the field, from questions at the sub-source level to questions at the activity level. The increasing number of studies on TPPR (transfer, persistence, prevalence, recovery) of DNA are of great help to answer such questions at the activity level. However, to date, little information is available about the actual numbers of cases in which activity level assessments were of relevance for the court. It must be considered an open question whether this increasing interest in activity level reporting (ALR) in the scientific community is based on an actual increase of requests for reporting in casework, or whether it is currently rather driven by a greater awareness for the complexity of DNA reporting in the academic arena itself. To assess this question for a part of Central Europe, we conducted an online survey in fourteen institutes in the German-speaking region of Switzerland, in Austria and in Germany over three months in spring 2024. Although the participants believe that ALR is useful for the evaluation of DNA evidence, they also report having limited knowledge therein and that it is in fact rarely requested in practice. No significant increase in ALR reporting was noted by the participants we surveyed over the last ten years. In addition to the development of ALR reporting, we also assessed evaluative sub-source level reporting (ESSLR) to monitor the potential effect of the advent of probabilistic genotyping on numbers of likelihood ratio (LR) calculations. It appears that most participating institutions still use binary/semi-continuous calculation software rather than fully continuous models. There has been no significant increase or decrease in LR calculations for single/major profiles, nor for DNA mixtures. The absence of ALR requests together with a constant number of ESSLR calculations thereby strongly suggests that the perceived shift from (sub-)sub-source level reporting to activity level reporting did not (yet) happen in German-speaking countries.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112729"},"PeriodicalIF":2.5,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145556525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Forensic science international
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1