首页 > 最新文献

Forensic science international最新文献

英文 中文
Culmination of molecular genomic techniques in forensic crime investigation 分子基因组技术在法医犯罪调查中的应用。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-18 DOI: 10.1016/j.forsciint.2024.112302
Sanmitro Bhattacherjee , Susmita Mukherjee , Asmita Podder , Sonali Paul
The advancements in the sectors of forensic science along with biological sciences has proved to be a cornerstone in serving justice to people across the world. Genes are the coding languages that the body uses to define the definite characteristics of a human being that differentiates that being amongst million others. Now, to distinguish and get hands on the criminals, unique techniques are developed and introduced in the market to be implemented in the real world in order to handout proper verdict by the judicial system. This paper deals with few of those molecular biology techniques that are implemented in forensics to unfold the reality of the cases. The paper discusses the basics, principles, pros, and cons along with the future aspects of the techniques with the reader and aims at clarifying the concept of analysis of the DNA. Techniques such as PCR, STR, mtDNA, NGS along with forensic DNA database CODIS are analysed in the paper which showcase the importance of the presence of a technique with a database for an optimal inference of the results.
事实证明,法医学和生物科学界的进步是为全世界人民伸张正义的基石。基因是人体用来确定人的明确特征的编码语言,它将人与其他人区分开来。现在,为了分辨和抓捕罪犯,市场上开发和引进了独特的技术,以便在现实世界中实施,由司法系统做出正确的判决。本文论述了在法医学中用于揭示案件真相的几种分子生物学技术。本文与读者讨论了这些技术的基本原理、原理、利弊和未来发展,旨在阐明 DNA 分析的概念。文中分析了 PCR、STR、mtDNA、NGS 等技术以及法医 DNA 数据库 CODIS,展示了一种技术和一个数据库对于最佳推断结果的重要性。
{"title":"Culmination of molecular genomic techniques in forensic crime investigation","authors":"Sanmitro Bhattacherjee ,&nbsp;Susmita Mukherjee ,&nbsp;Asmita Podder ,&nbsp;Sonali Paul","doi":"10.1016/j.forsciint.2024.112302","DOIUrl":"10.1016/j.forsciint.2024.112302","url":null,"abstract":"<div><div>The advancements in the sectors of forensic science along with biological sciences has proved to be a cornerstone in serving justice to people across the world. Genes are the coding languages that the body uses to define the definite characteristics of a human being that differentiates that being amongst million others. Now, to distinguish and get hands on the criminals, unique techniques are developed and introduced in the market to be implemented in the real world in order to handout proper verdict by the judicial system. This paper deals with few of those molecular biology techniques that are implemented in forensics to unfold the reality of the cases. The paper discusses the basics, principles, pros, and cons along with the future aspects of the techniques with the reader and aims at clarifying the concept of analysis of the DNA. Techniques such as PCR, STR, mtDNA, NGS along with forensic DNA database CODIS are analysed in the paper which showcase the importance of the presence of a technique with a database for an optimal inference of the results.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"366 ","pages":"Article 112302"},"PeriodicalIF":2.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental time pattern of Thanatophilus sinuatus at different constant and variable temperatures Thanatophilus sinuatus 在不同恒温和变温条件下的发育时间模式。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-16 DOI: 10.1016/j.forsciint.2024.112301
Shipeng Shao , Gengwang Hu , Liangliang Li , Yundi Gao , Ruonan Zhang , Siqi Liu , Hongfei Xu , Shuixiu Xia , Yu Wang
As a forensically important species, Thanatophilus sinuatus (Fabricius, 1775) (Coleoptera: Staphylinidae) is often active and widely distributed on animal and human carcasses. Although there is developmental data available for this species under small-group feeding conditions, there is still a lack of data on the developmental time of this species under aggregate feeding conditions, focusing on each developmental stage. Also, there are no studies on the development of this species under variable temperatures. Thus, this study focused on the aggregate rearing of T. sinuatus in China at seven constant temperatures and three variable temperatures from 16 to 34 °C, recording the developmental duration and accumulated degree days (ADD) of each developmental stage in detail. Additionally, body length, head capsule width and mesonotum width were measured at different times, and the survival rate was calculated for each stage. Based on the above data, an isomorphen diagram, the linear thermal summation models, the curvilinear Optim SSI models, and a survival curve were established and the head capsule width and mesonotum width were cluster analyzed to identify between instars. In addition, differences in total developmental time between constant and variable temperatures under the same mean temperature were compared to provide more comprehensive developmental data for estimating postmortem interval (PMI) using this species.
Thanatophilus sinuatus(Fabricius,1775 年)(鞘翅目:蝶形目)是一种重要的法医物种,经常活跃在动物和人类尸体上,分布广泛。虽然目前已有该物种在小群取食条件下的发育数据,但仍缺乏该物种在大群取食条件下各发育阶段的发育时间数据。此外,也没有关于该物种在不同温度条件下发育的研究。因此,本研究重点研究了中国在 7 个恒定温度和 3 个从 16 ℃ 到 34 ℃ 的变化温度条件下聚养 T. sinuatus 的情况,详细记录了每个发育阶段的发育持续时间和累积度日(ADD)。此外,还测量了不同时期的体长、头囊宽度和中鳞宽度,并计算了各阶段的存活率。根据上述数据,建立了等体图、线性热和模型、曲线 Optim SSI 模型和存活率曲线,并对头囊宽度和中鳞宽度进行聚类分析,以确定不同龄期之间的差异。此外,还比较了在相同平均温度下,恒温和变温在总发育时间上的差异,为利用该物种估计死后间隔(PMI)提供了更全面的发育数据。
{"title":"Developmental time pattern of Thanatophilus sinuatus at different constant and variable temperatures","authors":"Shipeng Shao ,&nbsp;Gengwang Hu ,&nbsp;Liangliang Li ,&nbsp;Yundi Gao ,&nbsp;Ruonan Zhang ,&nbsp;Siqi Liu ,&nbsp;Hongfei Xu ,&nbsp;Shuixiu Xia ,&nbsp;Yu Wang","doi":"10.1016/j.forsciint.2024.112301","DOIUrl":"10.1016/j.forsciint.2024.112301","url":null,"abstract":"<div><div>As a forensically important species, <em>Thanatophilus sinuatus</em> (Fabricius, 1775) (Coleoptera: Staphylinidae) is often active and widely distributed on animal and human carcasses. Although there is developmental data available for this species under small-group feeding conditions, there is still a lack of data on the developmental time of this species under aggregate feeding conditions, focusing on each developmental stage. Also, there are no studies on the development of this species under variable temperatures. Thus, this study focused on the aggregate rearing of <em>T. sinuatus</em> in China at seven constant temperatures and three variable temperatures from 16 to 34 °C, recording the developmental duration and accumulated degree days (ADD) of each developmental stage in detail. Additionally, body length, head capsule width and mesonotum width were measured at different times, and the survival rate was calculated for each stage. Based on the above data, an isomorphen diagram, the linear thermal summation models, the curvilinear Optim SSI models, and a survival curve were established and the head capsule width and mesonotum width were cluster analyzed to identify between instars. In addition, differences in total developmental time between constant and variable temperatures under the same mean temperature were compared to provide more comprehensive developmental data for estimating postmortem interval (PMI) using this species.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"366 ","pages":"Article 112301"},"PeriodicalIF":2.2,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detected substance abuse among injecting drug users through analysis of used syringes in Tunisia 通过分析突尼斯使用过的注射器发现注射吸毒者滥用药物的情况。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-15 DOI: 10.1016/j.forsciint.2024.112299
Bilel Moslah , Omar Smaoui , Thomas Néfau , Houyem Boukassoula , Nadia chaouali , Meriem Laaribi , Mohamed Anouar Nouioui , Dorra Amira , Abderrazek Hedhili

Background and aims

Injecting drug use poses significant public health risks due to unsafe practices such as syringe sharing, reuse, and risky sexual behaviors, which increase the transmission of bloodborne viruses. In Tunisia, limited data on injecting drug use hinders the development of informed health and harm reduction policies.

Methods

A syringe collection campaign was conducted in Tunis in November 2022. The used syringes were provided by the Tunisian Association for Information and Orientation on AIDS and Addiction (ATIOST), a harm-reduction service. These syringes had been distributed to people who inject drugs (PWID) as part of a mobile syringe exchange program. The objective of the study was to analyze the contents of the used syringes to gain further insights into drug use patterns among PWID. The residual substances in the syringes were examined using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), in accordance with the standardized protocol of the European Syringe Collection and Analysis Project Enterprise (ESCAPE).

Results

A total of 261 syringes from five collection sites were analyzed. Among these, 87 % contained at least one psychoactive substance, while 32 % contained more than two psychoactive substances. The most frequently identified psychoactive substances were buprenorphine (50.28 %), amphetamine (11.65 %) and tramadol (9.66 %). No substances were detected in 34 syringes.

Conclusion

This method provides rapid data on drug use trends in specific regions and timeframes, revealing differences that can inform tailored prevention and harm reduction strategies. Such analyses are valuable for comparative studies across countries in the European Neighbourhood Policy (ENP-South) region.
背景和目的:由于共用注射器、重复使用注射器和危险的性行为等不安全行为,注射吸毒带来了巨大的公共卫生风险,加剧了血液传播病毒的传播。在突尼斯,有关注射吸毒的数据有限,这阻碍了知情健康和减少伤害政策的制定:方法:2022 年 11 月在突尼斯开展了注射器收集活动。使用过的注射器由突尼斯艾滋病和毒瘾信息与指导协会(ATIOST)提供,这是一项减少伤害的服务。作为流动注射器交换计划的一部分,这些注射器已分发给注射吸毒者(PWID)。研究的目的是分析使用过的注射器中的成分,以进一步了解注射吸毒者的吸毒模式。根据欧洲注射器收集和分析项目企业(ESCAPE)的标准化方案,采用超高效液相色谱-串联质谱法(UPLC-MS/MS)对注射器中的残留物质进行了检测:共分析了来自五个收集点的 261 支注射器。其中,87%的注射器至少含有一种精神活性物质,32%的注射器含有两种以上的精神活性物质。最常发现的精神活性物质是丁丙诺啡(50.28%)、苯丙胺(11.65%)和曲马多(9.66%)。34 支注射器中未检测出任何药物:这种方法可以快速提供特定地区和时间段内毒品使用趋势的数据,揭示差异,为有针对性的预防和减少伤害策略提供信息。这种分析对于欧洲睦邻政策(ENP-South)地区各国之间的比较研究很有价值。
{"title":"Detected substance abuse among injecting drug users through analysis of used syringes in Tunisia","authors":"Bilel Moslah ,&nbsp;Omar Smaoui ,&nbsp;Thomas Néfau ,&nbsp;Houyem Boukassoula ,&nbsp;Nadia chaouali ,&nbsp;Meriem Laaribi ,&nbsp;Mohamed Anouar Nouioui ,&nbsp;Dorra Amira ,&nbsp;Abderrazek Hedhili","doi":"10.1016/j.forsciint.2024.112299","DOIUrl":"10.1016/j.forsciint.2024.112299","url":null,"abstract":"<div><h3>Background and aims</h3><div>Injecting drug use poses significant public health risks due to unsafe practices such as syringe sharing, reuse, and risky sexual behaviors, which increase the transmission of bloodborne viruses. In Tunisia, limited data on injecting drug use hinders the development of informed health and harm reduction policies.</div></div><div><h3>Methods</h3><div>A syringe collection campaign was conducted in Tunis in November 2022. The used syringes were provided by the Tunisian Association for Information and Orientation on AIDS and Addiction (ATIOST), a harm-reduction service. These syringes had been distributed to people who inject drugs (PWID) as part of a mobile syringe exchange program. The objective of the study was to analyze the contents of the used syringes to gain further insights into drug use patterns among PWID. The residual substances in the syringes were examined using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), in accordance with the standardized protocol of the European Syringe Collection and Analysis Project Enterprise (ESCAPE).</div></div><div><h3>Results</h3><div>A total of 261 syringes from five collection sites were analyzed. Among these, 87 % contained at least one psychoactive substance, while 32 % contained more than two psychoactive substances. The most frequently identified psychoactive substances were buprenorphine (50.28 %), amphetamine (11.65 %) and tramadol (9.66 %). No substances were detected in 34 syringes.</div></div><div><h3>Conclusion</h3><div>This method provides rapid data on drug use trends in specific regions and timeframes, revealing differences that can inform tailored prevention and harm reduction strategies. Such analyses are valuable for comparative studies across countries in the European Neighbourhood Policy (ENP-South) region.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112299"},"PeriodicalIF":2.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Findings of synthetic cathinones in post-mortem toxicology 尸检毒理学对合成卡西酮的发现。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-15 DOI: 10.1016/j.forsciint.2024.112297
Pirkko Kriikku , Ilkka Ojanperä
Synthetic cathinones (SCs) are a group of new psychoactive substances with amphetamine-like effects but generally higher potency. The aim of this study was to assess the incidence and significance of SCs in post-mortem (PM) investigations in Finland, focusing on the three most prevalent substances: α-PVP, α-PHP, and α-PiHP. All PM cases positive for SCs during 2018–2023 were investigated with respect to cause and manner of death, PM blood and urine concentrations, and concomitant use of other drugs of abuse. There were 136 findings of α-PVP, α-PHP, or α-PiHP in 118 death cases, in which the median age at death was 35 years and 82 % were males. Concomitant opioids, stimulants, or sedatives were found in 69–92 % of cases, and cannabis in 39–47 %. In two cases (1.7 %), SCs were the only findings of abused drugs. Thirty-four fatal poisonings (29 %) were identified in which at least one of the three SCs was implicated in the cause of death. The median (range) femoral blood concentrations of α-PVP, α-PHP, and α-PiHP in these poisoning cases were 0.18 (0.03–2.6) mg/L, 0.16 (0.02–0.58) mg/L, and 0.14 (0.03–2.1) mg/L, respectively. α-PVP, α-PHP and α-PiHP were found in 4.0 % of all drug abuse cases and in 2.7 % of all fatal poisonings related to drug abuse, while for amphetamine/methamphetamine, these figures were 44 % and 21 %, respectively. Despite their lower prevalence in PM cases, SCs appear to have similar abuse liability and similar drug use patterns to amphetamine.
合成卡西酮(SC)是一组新的精神活性物质,具有类似苯丙胺的效果,但一般药效更高。本研究旨在评估芬兰尸检(PM)中SCs的发生率和重要性,重点关注三种最普遍的物质:α-PVP、α-PHP和α-PiHP。对2018-2023年期间所有SCs阳性的PM病例进行了调查,调查内容包括死因和死亡方式、PM血液和尿液浓度以及同时使用其他滥用药物的情况。在118例死亡病例中有136例发现α-PVP、α-PHP或α-PiHP,其中死亡年龄中位数为35岁,82%为男性。在 69-92% 的病例中发现了阿片类药物、兴奋剂或镇静剂,在 39-47% 的病例中发现了大麻。在两个病例(1.7%)中,仅发现了 SCs。在已查明的 34 例致命中毒事件(29%)中,死因至少与三种 SCs 中的一种有关。在这些中毒病例中,α-PVP、α-PHP 和 α-PiHP 的股静脉血浓度中位数(范围)分别为 0.18(0.03-2.6)毫克/升、0.16(0.02-0.58)毫克/升和 0.14(0.03-2.1)毫克/升。在所有药物滥用病例中发现α-PVP、α-PHP和α-PiHP的比例分别为4.0%和2.7%,而苯丙胺/甲基苯丙胺的比例分别为44%和21%。尽管SC在PM病例中的流行率较低,但其滥用责任和药物使用模式似乎与苯丙胺相似。
{"title":"Findings of synthetic cathinones in post-mortem toxicology","authors":"Pirkko Kriikku ,&nbsp;Ilkka Ojanperä","doi":"10.1016/j.forsciint.2024.112297","DOIUrl":"10.1016/j.forsciint.2024.112297","url":null,"abstract":"<div><div>Synthetic cathinones (SCs) are a group of new psychoactive substances with amphetamine-like effects but generally higher potency. The aim of this study was to assess the incidence and significance of SCs in post-mortem (PM) investigations in Finland, focusing on the three most prevalent substances: α-PVP, α-PHP, and α-PiHP. All PM cases positive for SCs during 2018–2023 were investigated with respect to cause and manner of death, PM blood and urine concentrations, and concomitant use of other drugs of abuse. There were 136 findings of α-PVP, α-PHP, or α-PiHP in 118 death cases, in which the median age at death was 35 years and 82 % were males. Concomitant opioids, stimulants, or sedatives were found in 69–92 % of cases, and cannabis in 39–47 %. In two cases (1.7 %), SCs were the only findings of abused drugs. Thirty-four fatal poisonings (29 %) were identified in which at least one of the three SCs was implicated in the cause of death. The median (range) femoral blood concentrations of α-PVP, α-PHP, and α-PiHP in these poisoning cases were 0.18 (0.03–2.6) mg/L, 0.16 (0.02–0.58) mg/L, and 0.14 (0.03–2.1) mg/L, respectively. α-PVP, α-PHP and α-PiHP were found in 4.0 % of all drug abuse cases and in 2.7 % of all fatal poisonings related to drug abuse, while for amphetamine/methamphetamine, these figures were 44 % and 21 %, respectively. Despite their lower prevalence in PM cases, SCs appear to have similar abuse liability and similar drug use patterns to amphetamine.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112297"},"PeriodicalIF":2.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outside-in hair contamination by blood containing opiates and opioids 含有鸦片制剂和阿片类药物的血液对头发的外源性污染。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-15 DOI: 10.1016/j.forsciint.2024.112298
Alexandre Czech , Julien Scala-Bertola , Elise Pape , Allan Kolodziej , Nathalie Tscheiller , Jean-Yves Jouzeau , Elodie Marchand , Nicolas Gambier
Hair analysis for drugs has become extensively used for forensic investigation in recent years. To best interpret hair drug content in post-mortem conditions, the extent of external contamination by biological fluids, such as blood, must be taken into account to avoid false positive results. The present study evaluated opiates and opioids incorporation into hair from blood containing different concentrations of morphine (MOR), 6-mono-acetyl morphine (6-AM), codeine (COD), dihydrocodeine (DHC), tramadol (TRA), oxycodone (OXY), methadone (MET), 2-ethylidene-1,5-dimethyl-3,3- diphenyl pyrrolidine (EDDP), buprenorphine (BUP) and norbuprenorphine (NBUP). The hair strands contaminated by brief soaking into blood were stored at room temperature (RT) or at 4°C during 6 hours, 1, 3, 7 or 14 days. After decontamination by extensive washing, we show that all opiates and opioids were incorporated into hair within a few hours at RT and 4°C, without significant changes over time. The concentrations of opiates and opioids in hair reached the cut-off levels established by the Society of Hair Testing (SoHT) for therapeutic (MET, COD), or toxic or lethal (all other molecules) blood concentrations. The metabolite to parent drug concentration ratios were determined for NBUP/BUP, MOR/6-AM and EDDP/MET and could be helpful as indicators of blood external contamination.
近年来,毛发毒品分析已广泛用于法医调查。为了最好地解释死后毛发中的药物含量,必须考虑到血液等生物液体的外部污染程度,以避免出现假阳性结果。本研究评估了血液中不同浓度的吗啡(MOR)、6-单乙酰吗啡(6-AM)、可待因(COD)和二氢可待因(DHC)在毛发中的鸦片制剂和阿片类药物含量、在血液中含有不同浓度的吗啡(MOR)、6-单乙酰吗啡(6-AM)、可待因(COD)、双氢可待因(DHC)、曲马多(TRA)、羟考酮(OXY)、美沙酮(MET)、2-亚乙基-1,5-二甲基-3,3-二苯基吡咯烷(EDDP)、丁丙诺啡(BUP)和去甲丁丙诺啡(NBUP)的毛发。被血液短暂浸泡污染的发丝在室温(RT)或 4°C 下分别保存 6 小时、1 天、3 天、7 天或 14 天。经过大量清洗去污后,我们发现所有阿片剂和阿片类药物都在室温和 4 摄氏度下的几小时内融入头发中,随着时间的推移没有发生显著变化。头发中阿片剂和阿片类药物的浓度达到了毛发检测协会(SoHT)为治疗性(MET、COD)或毒性或致死性(所有其他分子)血药浓度设定的临界水平。测定了 NBUP/BUP、MOR/6-AM 和 EDDP/MET 的代谢物与母体药物浓度比,可作为血液外部污染的指标。
{"title":"Outside-in hair contamination by blood containing opiates and opioids","authors":"Alexandre Czech ,&nbsp;Julien Scala-Bertola ,&nbsp;Elise Pape ,&nbsp;Allan Kolodziej ,&nbsp;Nathalie Tscheiller ,&nbsp;Jean-Yves Jouzeau ,&nbsp;Elodie Marchand ,&nbsp;Nicolas Gambier","doi":"10.1016/j.forsciint.2024.112298","DOIUrl":"10.1016/j.forsciint.2024.112298","url":null,"abstract":"<div><div>Hair analysis for drugs has become extensively used for forensic investigation in recent years. To best interpret hair drug content in post-mortem conditions, the extent of external contamination by biological fluids, such as blood, must be taken into account to avoid false positive results. The present study evaluated opiates and opioids incorporation into hair from blood containing different concentrations of morphine (MOR), 6-mono-acetyl morphine (6-AM), codeine (COD), dihydrocodeine (DHC), tramadol (TRA), oxycodone (OXY), methadone (MET), 2-ethylidene-1,5-dimethyl-3,3- diphenyl pyrrolidine (EDDP), buprenorphine (BUP) and norbuprenorphine (NBUP). The hair strands contaminated by brief soaking into blood were stored at room temperature (RT) or at 4°C during 6 hours, 1, 3, 7 or 14 days. After decontamination by extensive washing, we show that all opiates and opioids were incorporated into hair within a few hours at RT and 4°C, without significant changes over time. The concentrations of opiates and opioids in hair reached the cut-off levels established by the Society of Hair Testing (SoHT) for therapeutic (MET, COD), or toxic or lethal (all other molecules) blood concentrations. The metabolite to parent drug concentration ratios were determined for NBUP/BUP, MOR/6-AM and EDDP/MET and could be helpful as indicators of blood external contamination.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112298"},"PeriodicalIF":2.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of visible-light and infrared photography for visualizing hematomas postmortem 比较可见光和红外线摄影对尸检血肿的观察效果。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-15 DOI: 10.1016/j.forsciint.2024.112300
Joel Bottoni , Thomas Rost , Holger Wittig , Melanie Bauer , Eva Scheurer , Claudia Lenz
Photography is essential in forensic medicine documentation. While visible-light photography uses the human eye's spectrum (approximately 380–780 nm), infrared (IR) photography captures wavelengths invisible to the naked eye (approximately 700–1100 nm). This study aimed to assess the reliability of IR photography in detecting subcutaneous hematomas in deceased individuals. In postmortem examinations of 23 individuals with different skin tones, 43 hematomas were evaluated; for ethical reasons, hematomas on the face, neck, hands, or feet were excluded. Standardized photographs were taken using two different cameras: a Nikon D810 (visible-light) and a Nikon D800E modified with a 700 nm IR filter. Subsequently, tissue samples including the hematomas were excised. Hematoma density was assessed on paraffin-embedded samples using a Keyence VHX 5000 digital microscope. Raw IR photographs were processed with Photoshop to obtain tonal values of the darkest hematoma spot and the brightest spot of the surrounding intact tissue. Visual inspection of the excised samples confirmed that infrared photography accurately depicted 100 % of the 43 hematomas, whereas using visible-light photography, only 53.5 % were well visible and 46.5 % poorly visible. Tonal values correlated positively with microscopic densities of the hematomas, yielding a moderate to strong linear correlation coefficient of 0.70 (p < 0.001). In conclusion, IR photography is highly reliable in visualizing subcutaneous hematomas and has clear advantages over visible-light photography. Our results suggest that IR photography could be valuable as an additional tool in depicting suspected hematomas in living individuals.
摄影在法医学记录中至关重要。可见光摄影使用的是人眼的光谱(约 380-780 纳米),而红外线(IR)摄影捕捉的是肉眼看不见的波长(约 700-1100 纳米)。本研究旨在评估红外摄影在检测死者皮下血肿方面的可靠性。在对 23 名不同肤色的死者进行的尸检中,对 43 个血肿进行了评估;出于道德原因,脸部、颈部、手部或脚部的血肿未包括在内。我们使用两台不同的相机拍摄了标准化照片:尼康 D810(可见光)和尼康 D800E(改装了 700 纳米红外滤光片)。随后,切除包括血肿在内的组织样本。使用 Keyence VHX 5000 数码显微镜评估石蜡包埋样本的血肿密度。使用 Photoshop 对原始红外照片进行处理,以获得血肿最暗处和周围完整组织最亮处的色调值。对切除样本的目视检查证实,红外摄影准确描绘了 43 个血肿中的 100%,而使用可见光摄影时,只有 53.5% 的血肿清晰可见,46.5% 的血肿模糊不清。色调值与血肿的显微密度呈正相关,线性相关系数为 0.70(p<0.05)。
{"title":"Comparison of visible-light and infrared photography for visualizing hematomas postmortem","authors":"Joel Bottoni ,&nbsp;Thomas Rost ,&nbsp;Holger Wittig ,&nbsp;Melanie Bauer ,&nbsp;Eva Scheurer ,&nbsp;Claudia Lenz","doi":"10.1016/j.forsciint.2024.112300","DOIUrl":"10.1016/j.forsciint.2024.112300","url":null,"abstract":"<div><div>Photography is essential in forensic medicine documentation. While visible-light photography uses the human eye's spectrum (approximately 380–780 nm), infrared (IR) photography captures wavelengths invisible to the naked eye (approximately 700–1100 nm). This study aimed to assess the reliability of IR photography in detecting subcutaneous hematomas in deceased individuals. In postmortem examinations of 23 individuals with different skin tones, 43 hematomas were evaluated; for ethical reasons, hematomas on the face, neck, hands, or feet were excluded. Standardized photographs were taken using two different cameras: a Nikon D810 (visible-light) and a Nikon D800E modified with a 700 nm IR filter. Subsequently, tissue samples including the hematomas were excised. Hematoma density was assessed on paraffin-embedded samples using a Keyence VHX 5000 digital microscope. Raw IR photographs were processed with Photoshop to obtain tonal values of the darkest hematoma spot and the brightest spot of the surrounding intact tissue. Visual inspection of the excised samples confirmed that infrared photography accurately depicted 100 % of the 43 hematomas, whereas using visible-light photography, only 53.5 % were well visible and 46.5 % poorly visible. Tonal values correlated positively with microscopic densities of the hematomas, yielding a moderate to strong linear correlation coefficient of 0.70 (p &lt; 0.001). In conclusion, IR photography is highly reliable in visualizing subcutaneous hematomas and has clear advantages over visible-light photography. Our results suggest that IR photography could be valuable as an additional tool in depicting suspected hematomas in living individuals.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"366 ","pages":"Article 112300"},"PeriodicalIF":2.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forensic footwear examination: A systematic review of the existing literature 法医鞋类检验:现有文献的系统回顾。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-14 DOI: 10.1016/j.forsciint.2024.112295
Danyela Kellett , Sanaz Zolghadriha , Ruth Morgan , David Lagnado , Sherry Nakhaeizadeh
Systematic reviews have been shown to be useful tools mainly in terms of identifying research areas, but the approach is less common in forensic science. Systematic reviews in forensic science have generally focused on topics closely linked to medicine or to the general practice of forensic science, such as cognitive bias or misleading evidence. The value of a systematic review is dependent on its transparency and reproducibility and, it is therefore of benefit to follow established guidelines, such as those published by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This paper applies these guidelines to conduct an effective systematic review of the types of research that have addressed forensic footwear examination. Using this approach, it was found that overall, there is a significant body of research that has been undertaken addressing forensic footwear examination, with 427 papers in the scope of the systematic review. The results showed that the largest proportion of papers published reported the use of an algorithm to produce an automated system to code footwear marks (25.1 %). However, only a small number of papers (1.2 %) related to the actual coding process with limited research into the use of footwear intelligence (2.1 %) and linking of scenes (0.7 %) which would follow on from pattern coding. Papers relating to the recovery and enhancement of footwear marks most frequently reported in the areas of casting (7.3 %), photography (6.3 %), chemical enhancement of marks in blood (5.9 %) and other chemical enhancement (5.6 %). A relatively small proportion of papers identified considered interpretation (15.5 %) and the characteristics of a footwear mark (12.2 %), with the former predominantly focused on general interpretation (5.9 %) and the latter on damage or randomly acquired features (6.1 %). Overall, the review suggested that more research is needed to address the use of footwear intelligence; to understand the properties of footwear prints used to compare and evaluate footwear marks; and to develop a robust, transparent and consistent method to interpret and express the significance of a footwear comparison. The latter would facilitate the clear and unambiguous communication of findings to the Criminal Justice System as a whole, including the expression of the uncertainty of the evidence.
系统综述主要在确定研究领域方面被证明是有用的工具,但这种方法在法医学中并不常见。法医学中的系统综述通常侧重于与医学或法医学一般实践密切相关的主题,如认知偏差或误导性证据。系统性综述的价值取决于其透明度和可重复性,因此,遵循既定的指导方针是有益的,例如 Cochrane 协作组织发布的指导方针和系统性综述和元分析首选报告项目(PRISMA)。本文运用这些指南对法医鞋类检查的研究类型进行了有效的系统综述。通过这种方法,我们发现,总体而言,针对法医鞋类检查的研究数量可观,有 427 篇论文纳入了系统综述的范围。结果显示,在已发表的论文中,使用算法生成鞋印自动编码系统的论文所占比例最大(25.1%)。然而,只有少数论文(1.2%)与实际编码过程有关,对鞋类智能的使用(2.1%)和场景链接(0.7%)的研究有限,而这是模式编码的后续工作。有关恢复和增强鞋印的论文最常见的领域是铸造(7.3%)、摄影(6.3%)、血印化学增强(5.9%)和其他化学增强(5.6%)。在已鉴定的论文中,考虑解释(15.5 %)和鞋印特征(12.2 %)的论文所占比例相对较小,前者主要集中于一般解释(5.9 %),后者主要集中于损坏或随机获得的特征(6.1 %)。总体而言,审查建议需要开展更多研究,以解决鞋类情报的使用问题;了解用于比较和评估鞋类印记的鞋类指纹的特性;以及制定一种可靠、透明和一致的方法来解释和表达鞋类比较的意义。后者将有助于向整个刑事司法系统明确无误地传达调查结果,包括表达证据的不确定性。
{"title":"Forensic footwear examination: A systematic review of the existing literature","authors":"Danyela Kellett ,&nbsp;Sanaz Zolghadriha ,&nbsp;Ruth Morgan ,&nbsp;David Lagnado ,&nbsp;Sherry Nakhaeizadeh","doi":"10.1016/j.forsciint.2024.112295","DOIUrl":"10.1016/j.forsciint.2024.112295","url":null,"abstract":"<div><div>Systematic reviews have been shown to be useful tools mainly in terms of identifying research areas, but the approach is less common in forensic science. Systematic reviews in forensic science have generally focused on topics closely linked to medicine or to the general practice of forensic science, such as cognitive bias or misleading evidence. The value of a systematic review is dependent on its transparency and reproducibility and, it is therefore of benefit to follow established guidelines, such as those published by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This paper applies these guidelines to conduct an effective systematic review of the types of research that have addressed forensic footwear examination. Using this approach, it was found that overall, there is a significant body of research that has been undertaken addressing forensic footwear examination, with 427 papers in the scope of the systematic review. The results showed that the largest proportion of papers published reported the use of an algorithm to produce an automated system to code footwear marks (25.1 %). However, only a small number of papers (1.2 %) related to the actual coding process with limited research into the use of footwear intelligence (2.1 %) and linking of scenes (0.7 %) which would follow on from pattern coding. Papers relating to the recovery and enhancement of footwear marks most frequently reported in the areas of casting (7.3 %), photography (6.3 %), chemical enhancement of marks in blood (5.9 %) and other chemical enhancement (5.6 %). A relatively small proportion of papers identified considered interpretation (15.5 %) and the characteristics of a footwear mark (12.2 %), with the former predominantly focused on general interpretation (5.9 %) and the latter on damage or randomly acquired features (6.1 %). Overall, the review suggested that more research is needed to address the use of footwear intelligence; to understand the properties of footwear prints used to compare and evaluate footwear marks; and to develop a robust, transparent and consistent method to interpret and express the significance of a footwear comparison. The latter would facilitate the clear and unambiguous communication of findings to the Criminal Justice System as a whole, including the expression of the uncertainty of the evidence.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112295"},"PeriodicalIF":2.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
According to forensic science recommendations, are carbon dots capable of reliably developing latent fingerprints? 根据法医学建议,碳点是否能够可靠地显现潜在指纹?
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-12 DOI: 10.1016/j.forsciint.2024.112291
Daniel da Silva Carvalho , Bernardo José Munhoz Lobo , Atailson Oliveira da Silva , Marcelo Henrique Sousa , Sebastião William da Silva
Carbon dots (CDs) are zero-dimensional carbon nanomaterials that have been subject of considerable interest due to their remarkable electronic and optical characteristics. Their adjustable properties have gathered attention in different fields, including biological sensing, drug delivery, photodynamic therapy, photocatalysis, solar cells, and latent fingerprint development. In forensic science, the frequently reported outstanding photoluminescence behavior and biocompatibility of CDs are particularly important. Therefore, the objective of this systematic review was to assess the reliability of the results presented in studies proposing CD-based solutions for latent fingerprint development. By standardizing procedures, forensic science guidelines are valuable references that provide a framework for comparing new development materials with established ones. These publications were used to generate key points that allowed for a more objective evaluation of the reviewed studies. Our analysis revealed that most of the studies were conducted under rather limited conditions, with significant potential for bias in the presentation and evaluation of the new results achieved by the new CD-based developmental materials.
碳点(CD)是一种零维碳纳米材料,因其显著的电子和光学特性而备受关注。它们的可调节性能在生物传感、药物输送、光动力疗法、光催化、太阳能电池和潜指纹开发等不同领域引起了人们的关注。在法医学中,经常报道的 CD 的出色光致发光性能和生物相容性尤为重要。因此,本系统综述的目的是评估提出基于光盘的潜伏指纹显现解决方案的研究结果的可靠性。通过标准化程序,法医学指南是宝贵的参考资料,为比较新的显影材料和已有材料提供了框架。我们利用这些出版物生成要点,以便对所审查的研究进行更客观的评估。我们的分析表明,大多数研究都是在相当有限的条件下进行的,在介绍和评价基于 CD 的新显影材料所取得的新成果时,很可能会出现偏差。
{"title":"According to forensic science recommendations, are carbon dots capable of reliably developing latent fingerprints?","authors":"Daniel da Silva Carvalho ,&nbsp;Bernardo José Munhoz Lobo ,&nbsp;Atailson Oliveira da Silva ,&nbsp;Marcelo Henrique Sousa ,&nbsp;Sebastião William da Silva","doi":"10.1016/j.forsciint.2024.112291","DOIUrl":"10.1016/j.forsciint.2024.112291","url":null,"abstract":"<div><div>Carbon dots (CDs) are zero-dimensional carbon nanomaterials that have been subject of considerable interest due to their remarkable electronic and optical characteristics. Their adjustable properties have gathered attention in different fields, including biological sensing, drug delivery, photodynamic therapy, photocatalysis, solar cells, and latent fingerprint development. In forensic science, the frequently reported outstanding photoluminescence behavior and biocompatibility of CDs are particularly important. Therefore, the objective of this systematic review was to assess the reliability of the results presented in studies proposing CD-based solutions for latent fingerprint development. By standardizing procedures, forensic science guidelines are valuable references that provide a framework for comparing new development materials with established ones. These publications were used to generate key points that allowed for a more objective evaluation of the reviewed studies. Our analysis revealed that most of the studies were conducted under rather limited conditions, with significant potential for bias in the presentation and evaluation of the new results achieved by the new CD-based developmental materials.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112291"},"PeriodicalIF":2.2,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-mortem iris biometrics – Field, applications and methods 死后虹膜生物识别技术--领域、应用和方法。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-12 DOI: 10.1016/j.forsciint.2024.112293
Mateusz Trokielewicz , Piotr Maciejewicz , Adam Czajka
Post-mortem iris recognition (PMIR) is a recently developed area of expertise falling into the broader category of biometric methods utilizing human iris features for the purpose of automatic or semi-automatic establishing or confirming one’s identity. Yet, contrary to traditional iris recognition applied to living individuals, post-mortem biometrics presents forensic experts and scientists with challenges that have previously been unknown and require novel approaches and development of new skills. This paper summarizes the current state of the art of research in this area, both with respect to studies exploring the feasibility of iris recognition in a forensic setting, as well as the challenges still pervasive in the scientific community and potential ways to overcome them. We argue that post-mortem iris biometrics can serve both as a way for improving iris recognition, as well as provide forensic examiners tools for extending knowledge and skills in their respective field.
死后虹膜识别(PMIR)是最近发展起来的一个专业领域,属于利用人体虹膜特征自动或半自动确定或确认身份的生物识别方法的大类。然而,与应用于活人的传统虹膜识别技术不同,死后生物识别技术给法医专家和科学家带来了以前未知的挑战,需要新方法和新技能的开发。本文总结了这一领域的研究现状,既包括探索法医环境下虹膜识别可行性的研究,也包括科学界仍然普遍存在的挑战以及克服这些挑战的潜在方法。我们认为,死后虹膜生物识别技术既可以作为提高虹膜识别率的一种方法,也可以为法医检验人员提供扩展各自领域知识和技能的工具。
{"title":"Post-mortem iris biometrics – Field, applications and methods","authors":"Mateusz Trokielewicz ,&nbsp;Piotr Maciejewicz ,&nbsp;Adam Czajka","doi":"10.1016/j.forsciint.2024.112293","DOIUrl":"10.1016/j.forsciint.2024.112293","url":null,"abstract":"<div><div>Post-mortem iris recognition (PMIR) is a recently developed area of expertise falling into the broader category of biometric methods utilizing human iris features for the purpose of automatic or semi-automatic establishing or confirming one’s identity. Yet, contrary to traditional iris recognition applied to living individuals, post-mortem biometrics presents forensic experts and scientists with challenges that have previously been unknown and require novel approaches and development of new skills. This paper summarizes the current state of the art of research in this area, both with respect to studies exploring the feasibility of iris recognition in a forensic setting, as well as the challenges still pervasive in the scientific community and potential ways to overcome them. We argue that post-mortem iris biometrics can serve both as a way for improving iris recognition, as well as provide forensic examiners tools for extending knowledge and skills in their respective field.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112293"},"PeriodicalIF":2.2,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smart tech meets forensics: Enhancing crime scene investigation with digital simulations 智能技术与法医学的结合:利用数字模拟加强犯罪现场调查。
IF 2.2 3区 医学 Q1 MEDICINE, LEGAL Pub Date : 2024-11-12 DOI: 10.1016/j.forsciint.2024.112296
Jing Ma
This study proposes the integration of artificial intelligence (AI), specifically reinforcement learning and immersive human-computer interaction, to enhance crime scene investigation (CSI) training and assessment in public security colleges and universities. By incorporating these technologies, the aim is to provide a more systematic, scientific, and efficient learning experience for students, while ensuring fair and impartial evaluation. The technical roadmap and implementation strategy for applying AI and immersive interaction in CSI training are outlined, along with an application plan for different stages of the training and assessment process. This integration seeks to standardize and optimize CSI training, improving both intelligence and efficiency while ensuring fairness in evaluations.
本研究建议整合人工智能(AI),特别是强化学习和沉浸式人机交互,以加强公安院校的犯罪现场调查(CSI)培训和评估。通过融入这些技术,旨在为学生提供更系统、更科学、更高效的学习体验,同时确保评价的公平公正。本文概述了在 CSI 培训中应用人工智能和沉浸式交互的技术路线图和实施策略,以及培训和评估过程不同阶段的应用计划。这种整合旨在规范和优化 CSI 培训,提高智能和效率,同时确保评估的公平性。
{"title":"Smart tech meets forensics: Enhancing crime scene investigation with digital simulations","authors":"Jing Ma","doi":"10.1016/j.forsciint.2024.112296","DOIUrl":"10.1016/j.forsciint.2024.112296","url":null,"abstract":"<div><div>This study proposes the integration of artificial intelligence (AI), specifically reinforcement learning and immersive human-computer interaction, to enhance crime scene investigation (CSI) training and assessment in public security colleges and universities. By incorporating these technologies, the aim is to provide a more systematic, scientific, and efficient learning experience for students, while ensuring fair and impartial evaluation. The technical roadmap and implementation strategy for applying AI and immersive interaction in CSI training are outlined, along with an application plan for different stages of the training and assessment process. This integration seeks to standardize and optimize CSI training, improving both intelligence and efficiency while ensuring fairness in evaluations.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"365 ","pages":"Article 112296"},"PeriodicalIF":2.2,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Forensic science international
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1