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Polyphenol-polysaccharide interactions: molecular mechanisms and potential applications in food systems - a comprehensive review. 多酚-多糖相互作用:分子机制及其在食品系统中的潜在应用综述。
IF 5.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-01-01 Epub Date: 2025-08-29 DOI: 10.1186/s43014-025-00322-3
Fereidoon Shahidi, Kerthika Devi Athiyappan

Polyphenols, a major class of plant secondary metabolites, are well known for their diverse bioactive properties. It has also been established that polyphenols interact with other macromolecules, such as proteins, polysaccharides, and lipids in the food matrix. Among the primary metabolites of the plant, carbohydrates play a significant role. Polyphenols and polysaccharides form complexes upon interaction; this interaction could be through covalent or non-covalent bonds, such as electrostatic, hydrophobic, van der Waals forces, and hydrogen bonding. These polysaccharide-polyphenol complexes exhibit enhanced bioactivity and influence the digestibility of complex macronutrients (such as proteins and polysaccharides), as well as their biological efficacy, bioavailability, and stability. Despite their numerous benefits and potential applications, the underlying mechanisms of interaction and complex formation between polysaccharides and polyphenols, as well as the influence of their structural parameters, remain underexplored. This comprehensive review summarizes the basic molecular-level implications of polysaccharides and polyphenols, exploring their potential applications in the food industry, and provides a basic understanding of their occurrence in various food matrices, characteristics of both polyphenols and polysaccharides that influence their interaction mechanisms, and detection under laboratory conditions. The review aims to bridge the gap between the molecular-level understanding of the complex and the development of potential nutraceuticals and functional food ingredients based on polysaccharide-polyphenol complexation.

Graphical abstract:

多酚是一类重要的植物次生代谢产物,具有多种生物活性。研究还发现,多酚与食物基质中的蛋白质、多糖和脂质等其他大分子相互作用。在植物的初级代谢产物中,碳水化合物起着重要的作用。多酚和多糖相互作用形成配合物;这种相互作用可以通过共价键或非共价键进行,如静电、疏水、范德华力和氢键。这些多糖-多酚复合物表现出增强的生物活性,并影响复合宏量营养素(如蛋白质和多糖)的消化率,以及它们的生物功效、生物利用度和稳定性。尽管多糖和多酚有许多好处和潜在的应用,但它们之间相互作用和复合物形成的潜在机制,以及它们的结构参数的影响,仍未得到充分的探索。本文综述了多糖和多酚在分子水平上的基本意义,探讨了它们在食品工业中的潜在应用,并对它们在各种食品基质中的存在、影响它们相互作用机制的多酚和多糖的特性以及在实验室条件下的检测提供了基本的了解。本文旨在弥合对多糖-多酚络合物的分子水平认识与基于多糖-多酚络合物的潜在营养保健和功能性食品成分开发之间的差距。图形化的简介:
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引用次数: 0
How to assess antioxidant activity? Advances, limitations, and applications of in vitro, in vivo, and ex vivo approaches. 如何评估抗氧化活性?体外、体内和离体方法的进展、局限性和应用。
IF 5.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-01-01 Epub Date: 2025-10-29 DOI: 10.1186/s43014-025-00326-z
Fereidoon Shahidi, Amal Samarasinghe

Antioxidants are crucial in combating oxidative stress-a key factor in chronic diseases like cancer and neurodegeneration-while also playing vital roles in food preservation, functional food, and nutraceutical development. Their efficacy is assessed through in vitro (e.g., DPPH, FRAP), in situ, ex vivo, and in vivo models, as well as animal and human clinical trials, each offering unique advantages but facing challenges in standardization and physiological relevance. Advances in microfluidics, AI, and nanotechnology are enabling high-throughput screening, while omics integration provides deeper mechanistic insights. This review explores current methodologies, applications in food and pharmaceuticals, and emerging trends, emphasizing the need for rigorous clinical validation and personalized approaches to bridge the gap between laboratory research and real-world antioxidant therapies.

Graphical abstract:

抗氧化剂在对抗氧化应激(癌症和神经退行性疾病等慢性疾病的关键因素)方面至关重要,同时在食品保存、功能性食品和营养品开发方面也起着至关重要的作用。通过体外(如DPPH、FRAP)、原位、离体和体内模型以及动物和人体临床试验来评估它们的疗效,每种方法都具有独特的优势,但在标准化和生理相关性方面面临挑战。微流体、人工智能和纳米技术的进步使高通量筛选成为可能,而组学集成提供了更深入的机制见解。这篇综述探讨了目前的方法,在食品和药品中的应用,以及新兴的趋势,强调需要严格的临床验证和个性化的方法来弥合实验室研究和现实世界的抗氧化治疗之间的差距。图形化的简介:
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引用次数: 0
The impact of consumer in-home cooking methods on the physicochemical, sensory, and nutritional attributes of plant-based meat analogues (PBMAs) and meat: a review. 消费者家庭烹饪方法对植物性肉类类似物(pbma)和肉类的理化、感官和营养属性的影响:综述
IF 5.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-01-01 Epub Date: 2025-09-23 DOI: 10.1186/s43014-025-00312-5
Inchara N Yoganarasimhaswamy, Yashodha Panagodage, Dominic Agyei, Marcia English, Biniam Kebede

The global demand for Plant-based meat analogues (PBMAs) is rising due to increasing vegetarianism, health and environmental concerns, and animal-welfare issues. However, PBMAs encounter several challenges that limit widespread acceptance, including inadequate physico-chemical, sensory, and nutritional attributes, and concerns about over-processing and potential food-safety risks. To address these challenges, initiatives such as using high-quality raw materials, blending various plant protein sources, and employing innovative processing techniques are underway. Consumer acceptance of PBMAs also depends on the type of in-home cooking method used to prepare these foods, and the goal in many cases is for the quality attributes after cooking to resemble that of meat. The objective of this review is to compare the effects of in-home cooking methods on the quality of meat products to better understand how PBMAs will perform relative to their animal-based counterparts. Here, research articles that evaluate the impact of different cooking methods (e.g., baking and pan-frying) on the quality of meat and PBMAs were systematically summarized and compared to demonstrate trends in changes related to the physicochemical, sensory, and nutritional attributes of these products. The results revealed that the type of cooking method significantly influenced consumers' acceptance of meat and PBMAs. Changes in physical properties such as cooking loss and water holding capacity (WHC) can affect texture and were dependent on cooking temperatures. However, these changes were not independent of the protein source (PBMAs) or muscle type (meat). For example, cooking at 70 °C decreased the amount of sulfhydryl content in PBMAs compared to pork and beef burgers (20 µmol/g vs. 65 µmol/g protein, respectively). Conversely, when cooking temperatures (> 120 °C) were used, maillard reaction resulted in favourable sensory (appearance and flavour) attributes in both types of products, however, in the presence of sugars and the amino acid asparagine, concerns about the presence of chemical hazards such as acrylamide increased. Microwave cooking also increased WHC and oil absorption properties of plant proteins which improved the mouthfeel of PMBAs. In conclusion, there is a need to optimize in-home cooking techniques to enhance desirable textures and flavours in PBMAs which will improve consumer acceptability of these products.

Graphical abstract:

由于素食主义、健康和环境问题以及动物福利问题的增加,全球对植物性肉类类似物(pbma)的需求正在上升。然而,pbma遇到了一些限制广泛接受的挑战,包括物理化学,感官和营养属性的不足,以及对过度加工和潜在食品安全风险的担忧。为了应对这些挑战,诸如使用高质量原材料、混合各种植物蛋白来源和采用创新加工技术等举措正在进行中。消费者对pbma的接受程度还取决于用于准备这些食物的家庭烹饪方法的类型,在许多情况下,其目标是烹饪后的质量属性与肉类相似。本综述的目的是比较家庭烹饪方法对肉制品质量的影响,以更好地了解pbma相对于动物性同类产品的表现。本文系统总结和比较了不同烹饪方法(如烘焙和煎炸)对肉类和pbma品质影响的研究文章,以展示这些产品的理化、感官和营养属性的变化趋势。结果显示,烹饪方法的类型显著影响消费者对肉类和pbma的接受程度。物理性质的变化,如蒸煮损失和保水能力(WHC)会影响质地,并取决于蒸煮温度。然而,这些变化并非与蛋白质来源(pbma)或肌肉类型(肉)无关。例如,与猪肉和牛肉汉堡相比,70°C烹饪降低了pbma中巯基含量(分别为20 μ mol/g和65 μ mol/g蛋白质)。相反,当使用烹饪温度(bb0 - 120°C)时,美拉德反应在两种类型的产品中都产生了良好的感官(外观和风味)属性,然而,在存在糖和氨基酸天冬酰胺的情况下,对丙烯酰胺等化学危害存在的担忧增加了。微波蒸煮还提高了植物蛋白的WHC和吸油性能,改善了pmba的口感。总之,有必要优化家庭烹饪技术,以增强pbma的理想质地和风味,从而提高消费者对这些产品的接受度。图形化的简介:
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引用次数: 0
Salmon processing discards: a potential source of bioactive peptides – a review 鲑鱼加工废弃物:生物活性肽的潜在来源--综述
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-07 DOI: 10.1186/s43014-023-00197-2
Vegneshwaran V. Ramakrishnan, A. Hossain, D. Dave, Fereidoon Shahidi
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引用次数: 0
Comparison of nutritional values of Mucuna pruriens L. (velvet bean) seeds with the most preferred legume pulses 绒豆种子与最受欢迎的豆类的营养价值比较
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-06 DOI: 10.1186/s43014-023-00187-4
Florence Boniface, W. Washa, S. Nnungu
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引用次数: 0
Antioxidant capacity of sesamol in Caenorhabditis elegans model system 芝麻酚在秀丽隐杆线虫模型系统中的抗氧化能力
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-05 DOI: 10.1186/s43014-023-00186-5
Jinian Huang, Shuning Qi, Qiang Sun, Guohui Song, Jixing Tang, Yuquan Duan
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引用次数: 0
Nutritional composition and mineral profile of leaves of Moringa oleifera provenances grown in Gaborone, Botswana 博茨瓦纳哈博罗内种植的油辣木叶片的营养成分和矿物质特征
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-04 DOI: 10.1186/s43014-023-00183-8
Eng P. Masitlha, E. Seifu, D. Teketay
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引用次数: 0
Quality of cultured eels as affected by pollution sources and risk assessment of dioxins and dioxin-like polychlorinated biphenyls 受污染源影响的养殖鳗鱼质量以及二恶英和二恶英类多氯联苯的风险评估
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-03 DOI: 10.1186/s43014-023-00182-9
Hao Liu, Jianan Chen, Meng Dong, Jie Pang, Lei Qin, Xuhui Huang
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引用次数: 0
Phenolic-rich lees from Philippine rice wine (tapuy) increases Caenorhabditis elegans lifespan in spite of having low antioxidant activity 菲律宾米酒(tapuy)中富含酚类的酒糟尽管抗氧化活性低,却能延长秀丽隐杆线虫的寿命
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-02 DOI: 10.1186/s43014-023-00181-w
Sean Philippe L. Chua, Lesley Dale Umayat, Paul Mark B. Medina
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引用次数: 0
Degree of food processing and breast cancer risk: a prospective study in 9 European countries. 食品加工程度与乳腺癌风险:9 个欧洲国家的前瞻性研究。
IF 4 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-01-01 Epub Date: 2024-10-09 DOI: 10.1186/s43014-024-00264-2
Manon Cairat, Sahar Yammine, Thibault Fiolet, Agnès Fournier, Marie-Christine Boutron-Ruault, Nasser Laouali, Francesca Romana Mancini, Gianluca Severi, Fernanda Morales Berstein, Fernanda Rauber, Renata Bertazzi Levy, Guri Skeie, Kristin Benjaminsen Borch, Anne Tjønneland, Lene Mellemkjær, Yan Borné, Ann H Rosendahl, Giovanna Masala, Maria Teresa Giraudo, Maria Santucci de Magistris, Verena Katzke, Rashmita Bajracharya, Carmen Santiuste, Pilar Amiano, Stina Bodén, Carlota Castro-Espin, Maria-Jose Sánchez, Mathilde Touvier, Mélanie Deschasaux-Tanguy, Bernard Srour, Matthias B Schulze, Marcela Guevara, Nathalie Kliemann, Jessica Blanco Lopez, Aline Al Nahas, Kiara Chang, Eszter P Vamos, Christopher Millett, Elio Riboli, Alicia K Heath, Carine Biessy, Vivian Viallon, Corinne Casagrande, Genevieve Nicolas, Marc J Gunter, Inge Huybrechts

Recent epidemiological studies have suggested a positive association between ultra-processed food consumption and breast cancer risk, although some studies also reported no association. Furthermore, the evidence regarding the associations between intake of food with lower degrees of processing and breast cancer risk is limited. Thus, we investigated the associations between dietary intake by degree of food processing and breast cancer risk, overall and by breast cancer subtypes in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Dietary intake of EPIC participants was assessed via questionnaires at baseline. More than 11,000 food ingredients were classified into four groups of food processing levels using the NOVA classification system: unprocessed/minimally processed (NOVA 1), culinary ingredients (NOVA 2), processed (NOVA 3) and ultra-processed (NOVA 4). Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of breast cancer per standard deviation increase in daily consumption (grams) of foods from each NOVA group. The current analysis included 14,933 breast cancer cases, diagnosed among the 318,686 EPIC female participants, (median follow-up of 14.9 years). No associations were found between breast cancer risk and the level of dietary intake from NOVA 1 [HR per 1 SD=0.99 (95% CI 0.97 - 1.01)], NOVA 2 [HR per 1 SD =1.01 (95% CI 0.98 - 1.03)] and NOVA 4 [HR per 1 SD =1.01 (95% CI 0.99 - 1.03)] foods. However, a positive association was found between NOVA 3 and breast cancer risk [HR per 1 SD =1.05 (95% CI 1.03 - 1.07)] which became non-significant after adjustment for alcohol intake [HR per 1 SD =1.01 (95% CI 0.98 - 1.05)] or when beer and wine were excluded from this group [HR per 1 SD =0.99 (95% CI 0.97 - 1.01)]. The associations did not differ by breast cancer subtype, menopausal status or body mass index. Findings from this large-scale prospective study suggest that the positive association between processed food intake and breast cancer risk was likely driven by alcoholic beverage consumption.

Graphical abstract:

Supplementary information: The online version contains supplementary material available at 10.1186/s43014-024-00264-2.

最近的流行病学研究表明,食用超加工食品与患乳腺癌的风险呈正相关,但也有一些研究报告称两者之间没有关联。此外,有关摄入加工程度较低的食物与乳腺癌风险之间关系的证据也很有限。因此,我们在欧洲癌症与营养前瞻性调查(EPIC)研究中调查了按食品加工程度划分的膳食摄入量与乳腺癌风险之间的关系,包括总体风险和乳腺癌亚型风险。EPIC 参与者的膳食摄入量在基线时通过问卷进行评估。采用NOVA分类系统将11000多种食品成分按食品加工程度分为四组:未加工/微加工(NOVA 1)、烹饪成分(NOVA 2)、加工(NOVA 3)和超加工(NOVA 4)。采用 Cox 比例危险模型估算了每增加一个标准差的 NOVA 组食品日消耗量(克)患乳腺癌的危险比 (HRs) 和 95% 置信区间 (CIs)。本次分析包括 318,686 名 EPIC 女性参与者中确诊的 14,933 例乳腺癌病例(中位数随访时间为 14.9 年)。未发现乳腺癌风险与 NOVA 1 [HR per 1 SD=0.99 (95% CI 0.97 - 1.01)]、NOVA 2 [HR per 1 SD =1.01 (95% CI 0.98 - 1.03)]和 NOVA 4 [HR per 1 SD =1.01 (95% CI 0.99 - 1.03)]食物的膳食摄入水平之间存在关联。然而,NOVA 3与乳腺癌风险之间存在正相关[HR per 1 SD =1.05 (95% CI 1.03 - 1.07)],但在调整酒精摄入量[HR per 1 SD =1.01 (95% CI 0.98 - 1.05)]或将啤酒和葡萄酒排除在外[HR per 1 SD =0.99 (95% CI 0.97 - 1.01)]后,这种正相关变得不显著。乳腺癌亚型、绝经状态或体重指数的不同,两者之间的关系也不尽相同。这项大规模前瞻性研究的结果表明,加工食品摄入量与乳腺癌风险之间的正相关很可能是由酒精饮料摄入量引起的:在线版本包含补充材料,可查阅 10.1186/s43014-024-00264-2。
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Food Production, Processing and Nutrition
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