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Flow velocity and implication on particle size of bottom sediment in the commodore channel lagos, southwestern nigeria 奈及利亚西南部拉各斯准将水道底沉积物流速及其对颗粒大小的影响
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.3
R. A, M. A. S
Flow velocity generally influences the erosion, transport and deposition of sediments. Flow velocity and in relation to particle size distribution in the Commodore channel was investigated with the Acoustic doppler current profiler (ADCP), echosounder and veen van grab. Those equipment were deployed through a low draft survey boat to acquire acoustic and sediment data covering the study area. The ADCP measured the current velocity along fourteen established transect lines while twenty surface sediments samples were collected along the banks and center of the channel respectively. Sediment samples were analyzed for grain size distributions and mineralogicaly composition while the acoustics data were analyzed with Matlab software to produce velocity profiles for the channel area. The study aimed to determine the magnitude and direction of flow of water along the channel with a view to ascertain the sediment transport process.  Results indicated no significant difference in flow velocities along the different channel points. The flow velocity was however slightly higher around the channel mouth than in mid and upper reaches of the channel. The flow velocities showed negative correlation of (– 0.54 and – 0.28) with the sediment characteristics indicating that the sediment particle size distributions is unrelated to the flow velocity. This anomaly in the equilibrium flow velocity suggest  the impact of dredging and the continuous ebbing and flooding of tidal water which resulted to reworking of the sediment particle sizes prior to deposition. The sediment distributions were fine sand, moderately sorted, fine skewed with leptokurtic peaked. Significant fractions of the sediments were deposited in fluvial and shallow marine environments while a few were deposited in the beach and turbidity environment.  Sediments and acoustic data interpreted from the study suggest that sediment supply to the area was by fluvial processes through the barrier lagoon drainage basin.
流速一般影响沉积物的侵蚀、搬运和沉积。使用声学多普勒电流剖面仪(ADCP)、回声测深仪和均匀面包车抓斗研究了Commodore通道中的流速及其与粒径分布的关系。这些设备通过一艘低吃水调查船部署,以获取覆盖研究区域的声学和沉积物数据。ADCP沿着14条既定的样线测量流速,同时分别沿着河岸和河道中心收集了20个表层沉积物样本。对沉积物样品进行粒度分布和矿物组成分析,同时利用Matlab软件对声学数据进行分析,得出河道区域的流速剖面。研究的目的是确定沿河道水流的大小和方向,以确定泥沙的搬运过程。结果表明,沿不同通道点的流速无显著差异。而河口附近的流速略高于中上游的流速。流速与泥沙特征呈负相关(- 0.54和- 0.28),表明泥沙粒度分布与流速无关。平衡流速的这种异常表明疏浚的影响和潮汐水的持续退潮和淹没导致沉积前沉积物粒度的重新加工。沉积物分布为细砂、中等分选、细斜、细峰顶。大部分沉积物沉积在河流和浅海环境中,少量沉积在海滩和浑浊环境中。从研究中解释的沉积物和声学数据表明,该地区的沉积物供应是通过屏障泻湖流域的河流作用。
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引用次数: 0
On the use of arima and garch in modelling nigeria’s naira – us dollar monthly exchange rates 关于使用arima和garch对尼日利亚奈拉-美元每月汇率进行建模
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.9
Ahmad Nafisat Tanko, Musa G K, Musa Salisu Auta
This paper aimed at modelling the volatility of monthly average official exchange rate (Naira/USD) using the Autoregressive Integrated Moving Average (ARIMA) and Generalized Autoregressive Conditional Heteroscedasticity (GARCH) for the period January, 1981 to December, 2021. The data for the study was obtained from Central Bank of Nigeria 2021 Statistical Bulletin. The time plot, Augmented Dickey Fuller (ADF) and Phillip’s Perron (PP) were used to check for the Stationarity of the Series. It was discovered that the series is not stationary, thus the need for differencing to make it stationary. Based on the findings of the study, it was concluded that the ARIMA (0, 2,2) and GARCH (1,1) with Student’s t-distribution are the optimal models for modeling monthly average official exchange rates return (Naira/USD) in Nigeria.
本文旨在利用自回归综合移动平均(ARIMA)和广义自回归条件异方差(GARCH)对1981年1月至2021年12月期间的月平均官方汇率(奈拉/美元)的波动率进行建模。该研究的数据来自尼日利亚中央银行2021年统计公报。时间图、ADF和PP分别用于检验序列的平稳性。人们发现这个级数是不平稳的,因此需要用微分使它平稳。根据研究结果,得出的结论是,具有学生t分布的ARIMA(0,2,2)和GARCH(1,1)是建模尼日利亚月平均官方汇率回报(奈拉/美元)的最佳模型。
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引用次数: 0
Heteroscedasticity of unknown form: a comparison of five heteroscedasticity-consistent covariance matrix (hccm) estimators 未知形式的异方差:五种异方差一致协方差矩阵(hccm)估计量的比较
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.10
Nwangburuka C, Ijomah M A, N. M T
Regression model applications frequently involve violations of the homoscedasticity assumption and the presence of high leverage points (HLPs). The Heteroscedasticity-Consistent Covariance Matrix (HCCM) estimator's impact in the presence of heteroscedasticity of an unknown form was investigated in this study. The effectiveness of five variations of HCCM namely White’s estimator (HC0), White-Hinkley (HC1), Mackinnon White (HC2), Davison –Mackinnon (HC3), and Cribari-Neto (HC4) were accessed to identify the optimal Heteroscedasticity-Consistent Covariance Matrix (HCCM) estimator. In the study a simulated dataset was analysed using the Econometric View Software Version 12. The Breush-Pagan Godfery’s test for heteroscedasticity was applied and p-value of 0.0123 was obtained indicating presence of heteroscedasticity in the model. Applying the HCCM estimators and comparing the Heteroskedasticity-consistent standard errors estimates showed that HCO had 124.104, HC1 had 1189.222, HC2 had 1175.282, HC3 had 1106.94 and HC4 had 1140.707. These results reveal that HC3 and HC4 produced smaller errors compared to HC0, HC1 and HC2. The study hence comes to the conclusion that when doing inferential tests using OLS regression, the use of HCSE estimator increases the researcher's confidence in the accuracy and potency of those tests. This study therefore suggests that to ensure that findings are not affected by heteroscedasticity; researchers should use HCCM estimator but precisely HC3 and HC4, as the presented better results in comparison to others.  
回归模型应用经常涉及违反均方差假设和高杠杆点(hlp)的存在。本研究探讨了异方差-一致协方差矩阵(HCCM)估计量在存在未知形式异方差时的影响。利用White’s estimator (HC0)、White- hinkley (HC1)、Mackinnon White (HC2)、Davison -Mackinnon (HC3)和Cribari-Neto (HC4)这5种HCCM变量的有效性来确定最优异方差-一致协方差矩阵(HCCM)估计量。在研究中,模拟数据集使用计量经济学视图软件版本12进行分析。采用brush - pagan Godfery检验,p值为0.0123,表明模型存在异方差。应用HCCM估计量,比较异方差一致的标准误差估计,HCO为124.104,HC1为1189.222,HC2为1175.282,HC3为1106.94,HC4为1140.707。这些结果表明,与HC0、HC1和HC2相比,HC3和HC4产生的误差较小。因此,研究得出的结论是,当使用OLS回归进行推理测试时,使用HCSE估计器增加了研究人员对这些测试的准确性和效力的信心。因此,本研究建议,为了确保研究结果不受异方差的影响;研究人员应该使用HCCM估计器,但准确地说是HC3和HC4,因为与其他估计器相比,它们的结果更好。
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引用次数: 0
Haematinic and immunomodulatory effects of leaf extract of gongronema latifolium following the onslaught of mucosa ulceration in wistar rats 黄竹叶提取物对wistar大鼠黏膜溃疡侵袭后的血液和免疫调节作用
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.6
Dasofunjo Kayode, Timothy Francisca M, Eyam John A, Asuquo Ukorebi U, Usin Saviour G, Ogri Maryval O, Andem Iyang E, Odu Franklin O, Osim Markpeace E, Mgbe Patience T
Helicobacter pylori (H. pylori) infection is a global public health problem; a higher burden of the infection was reported in developing countries including Nigeria and Cameroun. It has been associated with several gastrointestinal diseases, and recently implicated with some haematological abnormalities. This research was carried out to determine the effect of ethanol extract of Gongronema latifolium on haematological parameters of ulcerated Wistar rats.. The experiment was carried out on thirty-six (36) healthy male Wistar rats of weight ranges from (180-200) g. The rats were divide into six (6) groups of six (6) each. Group A served as  normal control, Group B (standard control), C and D was treated with100 and 200mg/kg body weight of extract of Gongronema latifolium respectively, Group E and F, was induced with ulcer and treated with   200 and 400mg/kg body weight of extract of Gongronema latifolium respectively .The extract was administered orally for 14 days. After 14 days of administration all rats were fasted for 14 hours, the rats were sacrificed and the blood was collected by cardiac puncture. Blood samples collected in to EDTA bottles were analyzed for haematological profile. The extract showed a significant increase in (p<0.05) in LYM, RBC, PLT, PCV, MXD, Hb, of the ulcerated rats when compared with the normal and standard control. However, the extracts of G. latifolium showed a significant decrease in (p>0.05) in WBC and HCT when compared with the normal control. This present study suggests that the extract of Gongronema latifolium following the onslaught of mucosa might fight against foreign infection possibly by phagocytosis or by generating antibodies that might enhance immune response possibly by immunomodulatory or suppressant or adjuvant action or by generating antibodies that might enhance immune response and might be a panacea to anaemic condition following mucosa ulceration.  
幽门螺杆菌感染是一个全球性的公共卫生问题;据报告,尼日利亚和喀麦隆等发展中国家的感染负担较高。它与几种胃肠道疾病有关,最近还与一些血液学异常有关。本研究旨在探讨红竹醇提物对溃疡大鼠血液学指标的影响。实验选用体重180-200 g的健康雄性Wistar大鼠36只,分为6组,每组6只。A组为正常对照组,B组(标准对照组)、C组和D组分别给予100和200mg/kg体重的红麻提取物治疗,E组和F组分别给予200和400mg/kg体重的红麻提取物治疗,灌胃14 D。给药14 d后,各组大鼠禁食14 h,处死,穿刺取血。收集的血液样本在EDTA瓶进行血液学分析。与正常对照组相比,该提取物显著提高了WBC和HCT (p0.05)。本研究提示,在粘膜遭受攻击后,红叶提取物可能通过吞噬作用或产生抗体来对抗外来感染,这种抗体可能通过免疫调节、抑制或辅助作用增强免疫反应,或者产生抗体来增强免疫反应,可能是治疗粘膜溃疡后贫血的灵丹妙药。
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引用次数: 0
Effect of placental location on intra-uterine growth restriction and gestational hypertension 胎盘位置对子宫内生长受限和妊娠期高血压的影响
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.12
Samuel Archibong Efanga, Akintunde Olusijibomi Akintomide, Samson Omini Paulinus, Okon Asuquo Okon
OBJECTIVES: To evaluate the relationship between uterine placental location and fetal growth restriction and gestational hypertension. MATERIALS AND METHOD: A prospective cross-sectional study done in the Department of Radiology of the University of Calabar Teaching Hospital (UCTH), Calabar, within a 4-month period. The study involved a total of 100 singleton pregnant women between 20 to 40 weeks of gestation who were aged 20 to 39 years. Analysis of the data was done using the statistical package for social science (SPSS) version 20 Inc. Chicago, IL. RESULTS: The frequency distribution of the placental locations were: anterior – 35%, postero-fundal – 36%, antero-fundal – 18% and posterior – 11%. The highest mean head circumference to abdominal circumference ratio (HC/AC) was seen in subjects with posterior placental location (1.03 ± 0.09), lowest mean estimated fetal weight (EFW) was seen in subjects with antero-fundal placental location (1.87 ± 0.92 kg) while the highest mean systolic and diastolic blood pressure were seen in subjects with postero-fundal placental location (113.89 ± 10.50 mmHg and 66.61 ± 7.07 mmHg) respectively. The lowest mean HC/AC was noted in subjects with anterior placental location (1.01 ± 0.08), the highest EFW was noted in subjects with postero-fundal placental location (2.26 ± 1.03 kg) while the lowest mean systolic and diastolic blood pressure were noted in subjects with posterior placental location (109.09 ± 5.39 mmHg and 61.82 ± 4.05 mmHg) respectively. There was no significant correlation between placental location and HC/AC, EFW, systolic blood pressure and diastolic blood pressure (p = 0.744, p = 0.567, p = 0.671, p = 0.936) respectively. CONCLUSION: Placental location in the uterus has no relationship with intrauterine growth restriction and the development of gestational hypertension in the second half of singleton pregnancies.  
目的:探讨子宫胎盘位置与胎儿生长受限及妊娠期高血压的关系。材料和方法:在卡拉巴大学教学医院(UCTH)放射科进行的一项前瞻性横断面研究,为期4个月。该研究共涉及100名怀孕20至40周、年龄在20至39岁之间的单胎孕妇。数据的分析是使用社会科学统计软件包(SPSS)版本20 Inc.。结果:胎盘位置的频率分布为:前位- 35%,后基底位- 36%,前基底位- 18%,后基底位- 11%。平均头围/腹围比(HC/AC)以胎盘后位最高(1.03±0.09),平均估计胎儿体重(EFW)以胎盘前位最低(1.87±0.92 kg),平均收缩压和舒张压以胎盘后位最高(113.89±10.50 mmHg和66.61±7.07 mmHg)。平均HC/AC在胎盘前位组最低(1.01±0.08),EFW在胎盘后位组最高(2.26±1.03 kg),平均收缩压和舒张压在胎盘后位组最低(109.09±5.39 mmHg和61.82±4.05 mmHg)。胎盘位置与HC/AC、EFW、收缩压、舒张压均无显著相关性(p = 0.744, p = 0.567, p = 0.671, p = 0.936)。结论:单胎妊娠后半期胎盘在子宫内的位置与宫内生长受限及妊娠高血压的发生无关。
{"title":"Effect of placental location on intra-uterine growth restriction and gestational hypertension","authors":"Samuel Archibong Efanga, Akintunde Olusijibomi Akintomide, Samson Omini Paulinus, Okon Asuquo Okon","doi":"10.4314/gjpas.v29i1.12","DOIUrl":"https://doi.org/10.4314/gjpas.v29i1.12","url":null,"abstract":"OBJECTIVES: To evaluate the relationship between uterine placental location and fetal growth restriction and gestational hypertension. \u0000MATERIALS AND METHOD: A prospective cross-sectional study done in the Department of Radiology of the University of Calabar Teaching Hospital (UCTH), Calabar, within a 4-month period. The study involved a total of 100 singleton pregnant women between 20 to 40 weeks of gestation who were aged 20 to 39 years. Analysis of the data was done using the statistical package for social science (SPSS) version 20 Inc. Chicago, IL. \u0000RESULTS: The frequency distribution of the placental locations were: anterior – 35%, postero-fundal – 36%, antero-fundal – 18% and posterior – 11%. The highest mean head circumference to abdominal circumference ratio (HC/AC) was seen in subjects with posterior placental location (1.03 ± 0.09), lowest mean estimated fetal weight (EFW) was seen in subjects with antero-fundal placental location (1.87 ± 0.92 kg) while the highest mean systolic and diastolic blood pressure were seen in subjects with postero-fundal placental location (113.89 ± 10.50 mmHg and 66.61 ± 7.07 mmHg) respectively. The lowest mean HC/AC was noted in subjects with anterior placental location (1.01 ± 0.08), the highest EFW was noted in subjects with postero-fundal placental location (2.26 ± 1.03 kg) while the lowest mean systolic and diastolic blood pressure were noted in subjects with posterior placental location (109.09 ± 5.39 mmHg and 61.82 ± 4.05 mmHg) respectively. There was no significant correlation between placental location and HC/AC, EFW, systolic blood pressure and diastolic blood pressure (p = 0.744, p = 0.567, p = 0.671, p = 0.936) respectively. \u0000CONCLUSION: Placental location in the uterus has no relationship with intrauterine growth restriction and the development of gestational hypertension in the second half of singleton pregnancies. \u0000 ","PeriodicalId":12516,"journal":{"name":"Global Journal of Pure and Applied Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84948735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uv-spectroscopic and iodometric back titration analysis of total caffeine content of energy drinks available in markets in cross river state, south-south, nigeria 尼日利亚南南克罗斯河州市场上出售的能量饮料中咖啡因总含量的紫外光谱和碘量反滴定分析
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.1
F. C Asogwa, G. W Ugodi, R. S Ebugosi, I. N Achara, H. N Achieti Atim
Caffeine is an active ingredient of energy drinks that is often consumed to improve cognizance and physical cum mental alertness. This research aims to quantitatively analyze the caffeine content in serving volumes of energy drinks by spectrophotometric and iodometric back titration methods. In the spectrophotometric method, the determination of caffeine content was carried out using a maximum wavelength of 270 nm. The results show that the caffeine contents of the energy drinks were 37.40 mg/200 mL (Passion) < 64.73 mg/250 mL (Bullet) < 82.70 mg/355 mL (Power Horse) < 86.30 mg/400 mL (Predator) < 114.68 mg/500 mL (Fearless) while the iodometric back titration method showed 57.50 mg/250 mL, 165.00 mg/500 mL, 160.00 mg/400 mL, 117.15 mg/355 mL and 40 mg/200 mL respectively for Bullet, fearless, Predator, Power Horse and Passion. The labeled claims on the energy drinks were 78.75 mg/250 mL, 157.50 mg/500 mL, 120.00 mg/400 mL, 133.60 mg/355 mL and 50 mg/200 mL respectively for Bullet, fearless, Predator, Power Horse and Passion which indicates that manufacturers reported higher values of caffeine content in their product possibly to make it attractive to consumers.
咖啡因是能量饮料中的一种活性成分,经常被用来提高认知能力和身心警觉性。本研究旨在用分光光度法和碘量反滴定法定量分析功能饮料中咖啡因的含量。分光光度法测定咖啡因的含量,最大波长为270 nm。结果表明,能量饮料的咖啡因含量分别为37.40 mg/200 mL (Passion) < 64.73 mg/250 mL (Bullet) < 82.70 mg/355 mL (Power Horse) < 86.30 mg/400 mL (Predator) < 114.68 mg/500 mL (Fearless),而碘量反滴定法测定的结果显示,Bullet、Fearless、Predator、Power Horse和Passion的咖啡因含量分别为57.50 mg/250 mL、165.00 mg/500 mL、160.00 mg/400 mL、117.15 mg/355 mL和40 mg/200 mL。Bullet、fearless、Predator、Power Horse和Passion的能量饮料标签分别为78.75 mg/250 mL、157.50 mg/500 mL、120.00 mg/400 mL、133.60 mg/355 mL和50 mg/200 mL,这表明生产商在其产品中报告了较高的咖啡因含量,可能是为了吸引消费者。
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引用次数: 0
Comparative study of the effects of simulation models on the electronic and electrical parameters of a silicon pv cell 模拟模型对硅光伏电池电学参数影响的比较研究
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.5
Kpéli Esso Ehanam Tchedre, M. Savadogo, Guy Serge Tchouadep, I. Zerbo, M. Zoungrana
  For silicon solar cells simulation studies, one dimensional (1D), two dimensional 2D) and t   hree dimensional (3D) models are used. Depending of model proposed and assumptions done for the study, the electronic and electrical parameters and then the performance of the solar cell can be influenced. This situation raises the problem of the relevance of the choice of the study model and the quality of the resulting results. This work, propose comparative study of the electronic and electric parameters of 1D model, 3D analytical model and 3D empirical model. In this study, continuity equations of excess minority electrons are solved for 1D and 3D models and analytical expressions of electronic parameters (density of electrons δ, intrinsic junction recombination velocity Sf0 and recombination velocity at back surface Sb) and electric parameters (Jsc, Voc, η) are derived. The influence of the model chosen on the electric and electronic parameters of the PV cell have been presented. It appears in this study that the choice of the simulation model has a large influence on the electronic and electrical parameters the PV cell. The one-dimensional formulation (1D) overestimates the solar cell efficiency comparatively to the three-dimensional (3D) formulations. The study put in evidence also that for the same grain size, the solar cell efficiency resulting of 3D classical formulation is overestimates than one resulting of 3D empirical formulation.    
对于硅太阳能电池的模拟研究,使用一维(1D),二维(2D)和三维(3D)模型。根据所提出的模型和所做的假设,可以影响太阳能电池的电子和电气参数,进而影响太阳能电池的性能。这种情况提出了研究模型的选择和结果质量的相关性问题。本文提出了对一维模型、三维解析模型和三维经验模型的电、电参数进行比较研究。在本研究中,求解了一维和三维模型中过量少数电子的连续性方程,推导了电子参数(电子密度δ、本征结复合速度Sf0和后表面复合速度Sb)和电参数(Jsc、Voc、η)的解析表达式。给出了模型的选择对光伏电池电学参数的影响。在本研究中可以看出,仿真模型的选择对光伏电池的电子和电气参数有很大的影响。与三维(3D)配方相比,一维配方(1D)高估了太阳能电池效率。研究还表明,在相同晶粒尺寸的情况下,三维经典配方的太阳能电池效率比三维经验配方的效率要高。
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引用次数: 0
Evaluation of serum cotinine, total protein, thiocyanate, neuron specific enolase and uric acid levels of cigarette smokers in calabar metropolis, nigeria: a cross sectional study 尼日利亚卡拉巴尔市吸烟者血清可替宁、总蛋白、硫氰酸盐、神经元特异性烯醇化酶和尿酸水平的评估:一项横断研究
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.7
Eworo R E, Fabian U A, Thomas C, Luke U O, Usoro C A, Johnson D D, Egom O U, Ntamu A N, Nsonwu Anyanwu C A
Cigarette smoke contains harmful chemicals with deleterious health effects leading to oxidative stress and neuronal damage. This study investigated the levels of serum cotinine (COT), thiocyanate (thioc), uric acid (UA), neuron specific enolase (NSE), and the association between these variables in cigarette smokers. This cross sectional study enrolled 60 cigarette smokers and 45 non-smokers as participants. Serum thiocyanate and UA were estimated by colorimetric methods. Serum cotinine and NSE were determined by ELISA methods. Height and weight were measured and BMI computed. Data were analyzed using Student’s t-test, ANOVA, and Pearson’s correlation at P<0.05. Serum cotinine, thioc and NSE concentrations were significantly higher while BMI and UA levels were significantly lower (P<0.05) in smokers than in the controls. Age was not significantly different between the two groups (P>0.05). Age, COT, UA, thioc and NSE vary significantly (P<0.05) between the light, moderate and heavy cigarette smokers. From the least significant difference post hoc analyses, the mean age and UA level of light smoker were significantly higher (P<0.05) compared with the moderate smokers, while COT level of moderate smokers was significantly higher (P<0.05) compared with light smokers. Neuron specific enolase level of moderate cigarette smokers was higher (P>0.05) compared with the light smokers. The mean age of light smokers was significantly higher (P<0.05) compared with the heavy smokers, while the COT, thioc and NSE levels of light smokers were significantly lower (P<0.05) compared with the heavy smokers. Serum UA, thioc and NSE levels of moderate smokers were significantly lower (P<0.05), than those of the heavy smokers. Significant negative correlations were observed between age and COT (r = -0.554, P<0.001), age and thioc (r = -0.421, P= 0.001), age and NSE (r = -0.346, P=0.001), age against smoking pack years (r = -0.623, P<0.001) respectively. Significant positive correlations were observed between serum thioc and NSE (r = 0.324, P=0.012), COT against smoking pack years (r = 0.399, P=0.002), and NSE against smoking pack years (r = 0.311, P=0.015), correspondingly. This study has shown that high levels of cotinine and thiocyanate are associated with increased levels of neuron specific enolase, smoking pack years and decreased uric acid in smokers.
香烟烟雾中含有有害的化学物质,对健康有害,会导致氧化应激和神经元损伤。本研究调查了吸烟者血清中可替宁(COT)、硫氰酸盐(thioc)、尿酸(UA)、神经元特异性烯醇化酶(NSE)的水平,以及这些变量之间的关系。这项横断面研究招募了60名吸烟者和45名不吸烟者作为参与者。用比色法测定血清硫氰酸盐和尿酸。ELISA法测定血清可替宁和NSE。测量身高和体重,计算BMI。数据分析采用学生t检验、方差分析和Pearson相关(P0.05)。年龄、COT、UA、bmi、NSE与轻度吸烟者比较差异有统计学意义(P0.05)。轻度吸烟者的平均年龄显著高于重度吸烟者(P<0.05),轻度吸烟者的COT、thioc和NSE水平显著低于重度吸烟者(P<0.05)。中度吸烟者血清UA、thin、NSE水平显著低于重度吸烟者(P<0.05)。年龄与COT (r = -0.554, P<0.001)、年龄与体重(r = -0.421, P=0.001)、年龄与NSE (r = -0.346, P=0.001)、年龄与吸烟包年限(r = -0.623, P<0.001)呈显著负相关。血清浓度与NSE (r = 0.324, P=0.012)、COT与吸烟包年限(r = 0.399, P=0.002)、NSE与吸烟包年限(r = 0.311, P=0.015)呈显著正相关。这项研究表明,高水平的可替宁和硫氰酸盐与吸烟者神经元特异性烯醇化酶水平升高、吸烟年限和尿酸降低有关。
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引用次数: 0
Environmental pollution as health depreciator: the case of household generator use in nigeria 环境污染作为健康折旧:以尼日利亚家用发电机使用为例
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.2
O. O C, O. O O, Falana A R, Adeoye A S, O. J O, Marizu J T
The peculiarities of poor electricity generation and distribution which has resulted in high reliance on generators is implicated in the profile of Nigeria’s environmental pollution situation. Still, the consequences of the pervasive use of generators on health is yet to be optimally captured empirically, and macro-wise. Hence, this work was designed to examine correlations between generator use and some selected indices of- health. depreciator. Cross national, secondary data used were extracted from the 2018/19 Nigerian General Household Survey Panel Component (the 2018/19 GHS-Panel). Data on generator use and some selected indices of ill-health were subjected to descriptive and Spearman rank correlational analysis. Results indicated that generator is owned in 24.6% of Nigerian households. Only 55.4% of households have access to electricity; 11.3% and 12.4% of them primarily and secondarily rely on generators respectively. Male and female respondents reporting any health problem was 22.6% and 22.5% respectively, of which only 20.5% consulted a health practitioner. Respondents reporting drug purchase were 28.8%.  Primary reliance on generator significantly and positively correlated with consultation with health practitioner (r = .879, p< 0.05), female health problems (r = .862, p< 0.05), drug purchase (r = .700, p< 0.05), cost of medication (r = .700, p< 0.05), male health problems (r = .667, p = 0.05) and cost of consultation (r = .667, p = 0.05). On the other hand, the use of generator as a secondary or other source of electricity is only significantly and positively related to cost of medication (r = .733, p< 0.05) and drug purchase (r = .717, p< 0.05). Generators are leading assets whose use is becoming a significant element of the Nigerian way of life. Marginal or zero reliance on generator for access to electricity would have kept the Nigerian people healthier than they are currently. Certainly, generator use is a vast sponsor of ill-health and a vicious depreciator of health in Nigeria.
尼日利亚环境污染状况的概况涉及到发电和配电状况不佳的特点,造成对发电机的高度依赖。尽管如此,普遍使用发电机对健康的影响仍有待从经验和宏观角度得到最佳把握。因此,这项工作旨在检查发电机使用与某些选定的健康指数之间的相关性。depreciator。所使用的跨国二手数据取自2018/19年尼日利亚综合家庭调查小组组成部分(2018/19年ghs小组)。发电机使用数据和一些选定的不健康指标进行描述性和斯皮尔曼秩相关分析。结果表明,24.6%的尼日利亚家庭拥有发电机。只有55.4%的家庭用上了电;其中主要依靠发电机的占11.3%,次要依靠发电机的占12.4%。报告有任何健康问题的男性和女性受访者分别为22.6%和22.5%,其中只有20.5%的人咨询过保健医生。受访者表示购买过药品的占28.8%。初级依赖发生器与咨询医生(r = .879, p< 0.05)、女性健康问题(r = .862, p< 0.05)、药品购买(r = .700, p< 0.05)、用药费用(r = .700, p< 0.05)、男性健康问题(r = .667, p = 0.05)、咨询费用(r = .667, p = 0.05)呈显著正相关。另一方面,发电机作为二次电源或其他电源使用仅与用药费用(r = .733, p< 0.05)和药品购买(r = .717, p< 0.05)呈显著正相关。发电机是领先的资产,其使用正在成为尼日利亚生活方式的重要组成部分。在获得电力方面对发电机的依赖很少或不依赖将使尼日利亚人民比现在更健康。当然,在尼日利亚,发电机的使用是健康状况不佳的主要原因,也是健康状况恶性贬值的原因。
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引用次数: 0
Enhancement of oxidative stress, oxidative dna damage and lowered pefr in gasoline station attendants in calabar metropolis 卡拉巴尔市加油站服务人员氧化应激增强、氧化dna损伤及降低pefr
Pub Date : 2023-05-16 DOI: 10.4314/gjpas.v29i1.8
Eworo R E, Nsonwu Anyanwu C A, Usoro C A, Thomas C, Fabian U A, Johnson D D, Usoro C A O
Exposure to gasoline fumes through inhalation or accidental ingestion has been associated with chronic inflammatory reactions leading to oxidative stress, oxidative DNA damage and increased risk of chronic lung conditions and cancer. This study assessed the peak expiratory flow rate (PEFR) and biomarkers of oxidative stress (total antioxidant capacity (TAC), total plasma peroxides (TPP), oxidative stress index (OSI)), oxidative DNA damage (8-hydroxy-2-deoxyguanosine (8-OHdG)), 1-hydroxypyrene and urine creatinine in Gasoline Station Attendants. A total of 100 consenting adults, aged 18-60 years, comprising 50 gasoline station attendants and 50 non-gasoline station attendants (controls) were enrolled into this comparative cross-sectional study. The PEFR was determined using the peak flow meter, TAC, TPP and creatinine by colorimetry, 8-OHdG by enzyme linked immunosorbent assay (ELISA), 1-hydroxypyrene (1-HOP) by high performance liquid chromatography and OSI by calculation. Data was analysed using unpaired Student t-test and Pearson's correlation analysis at p<0.05. The body mass index, TPP, OSI and 8-OHdG levels were significantly higher and TAC and PEFR lower in gasoline pump attendants compared to the control groups (p<0.05). Positive correlations were observed between TPP and years at work (r=0.638, p=0.000), between TPP and OSI (r=0.282, p=0.047) and negative correlation between TAC and OSI (r=-0.555, p=0.000) only in gasoline station attendants. Exposure to gasoline is associated with increased lipid peroxidation and oxidative DNA damage, reduced lung function and depletion of antioxidants which may result in oxidative stress and increased risk for the development of chronic lung conditions in gasoline station attendants.  
通过吸入或意外摄入接触汽油烟雾与导致氧化应激、氧化DNA损伤和慢性肺病和癌症风险增加的慢性炎症反应有关。本研究评估了加油站服务员呼气峰流量(PEFR)和氧化应激生物标志物(总抗氧化能力(TAC)、总血浆过氧化物(TPP)、氧化应激指数(OSI))、氧化DNA损伤(8-羟基-2-脱氧鸟苷(8-OHdG))、1-羟基芘和尿肌酐。共有100名年龄在18-60岁之间的成年人,包括50名加油站服务员和50名非加油站服务员(对照组)被纳入这项比较横断面研究。PEFR采用峰值流量法测定,TAC、TPP和肌酐采用比色法测定,8-OHdG采用酶联免疫吸附法(ELISA)测定,1-羟基芘(1-HOP)采用高效液相色谱法测定,OSI计算法测定。数据分析采用unpaired Student t检验和Pearson相关分析,p<0.05。与对照组相比,汽油泵组的体重指数、TPP、OSI和8-OHdG水平显著升高,TAC和PEFR水平显著降低(p<0.05)。TPP与工作年限呈正相关(r=0.638, p=0.000), TPP与OSI呈正相关(r=0.282, p=0.047),而TAC与OSI仅在加油站服务员中呈负相关(r=-0.555, p=0.000)。接触汽油会增加脂质过氧化和氧化性DNA损伤,降低肺功能和消耗抗氧化剂,这可能导致氧化应激,增加加油站服务员患慢性肺病的风险。
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引用次数: 0
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Global Journal of Pure and Applied Sciences
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